Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Researcher

Eef Parthoens

Awards & Distinctions

25 Results

2024

MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids

Georgios MoschonasLouis DelhayeRobin CooremanFranziska HuesersAnayat BhatZoi StylianidouElien De BousserLaure De PryckHanna GrzesikDelphine De Sutter et al.

A1 Journal Article in CELL HOST & MICROBE

2021

Low-grade peripheral inflammation affects brain pathology in the App(NL-G-F)mouse model of Alzheimer's disease

Junhua XieNina GorléCharysse VandendriesscheGriet Van ImschootElien Van WonterghemCaroline Van CauwenbergheEef ParthoensEvelien Van HammeSaskia LippensLien Van Hoecke et al.

A1 Journal Article in ACTA NEUROPATHOLOGICA COMMUNICATIONS

2020

Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation

Jing LiuTim HebbrechtToon BransEef ParthoensSaskia LippensChengnan LiHerlinde De KeersmaeckerWinnok H. De VosStefaan De SmedtRabah Boukherroub et al.

A1 Journal Article in NANO RESEARCH

2019

A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation

Simon TavernierV AthanasopoulosPATRICK VERLOOG BehrensJens StaalDelfien BogaertLeslie NaesensMarieke De BruyneSofie Van GassenEef Parthoens et al.

A1 Journal Article in NATURE COMMUNICATIONS

Epithelial HMGB1 delays skin wound healing and drives tumor initiation by priming neutrophils for NET formation

Esther HosteChristian MaueröderLisette Van HoveLeen CatrysseHanna-Kaisa VikkulaMozes SzeBastiaan MaesDyah KarjosukarsoLiesbet MartensAmanda Gonçalves et al.

A1 Journal Article in CELL REPORTS

Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis

Karolina SlowickaInmaculada Serramito-GómezEmilio Boada-RomeroArne MartensMozes SzeIoanna PettaHanna-Kaisa VikkulaRiet De RyckeEef ParthoensSaskia Lippens et al.

A1 Journal Article in NATURE COMMUNICATIONS

Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture

Nathalia Moraes de VasconcelosNina Van OpdenboschHanne Van GorpEef ParthoensMohamed Lamkanfi

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2018

A CARD9 founder mutation disrupts NF-κB signaling by inhibiting BCL10 and MALT1 recruitment and signalosome formation

Marieke De BruyneLevi HosteDelfien BogaertLien Van den BosscheSimon TavernierEef ParthoensMélanie MigaudDeborah KonopnickiJean Cyr YombiBart Lambrecht et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Repeated photoporation with graphene quantum dots enables homogeneous labeling of live cells with extrinsic markers for fluorescence microscopy

Jing LiuRanhua XiongToon BransSaskia LippensEef ParthoensFrancesca Cella ZanacchiRaffaella MagrassiSantosh K SinghSreekumar KurungotSabine Szunerits et al.

A1 Journal Article in LIGHT-SCIENCE & APPLICATIONS

2017

Oral delivery of Escherichia coli persistently infected with M2e-displaying bacteriophages partially protects against influenza A virus

Lei DengKenny RooseEmma JobRiet De RyckeEvelien Van HammeAmanda GonçalvesEef ParthoensLaetitia CiccheleroNiek SandersWalter Fiers et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival

Simon TavernierFabiola OsorioLana VandersarrenJessica VettersNele VanlangenakkerGert Van IsterdaelKarl VergoteRiet De RyckeEef ParthoensLianne van de Laar et al.

A1 Journal Article in NATURE CELL BIOLOGY

2015

NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest

Vanessa AndriesKarl VandepoeleKatrien StaesGeert BerxPieter BogaertGert Van IsterdaelDaisy GinnebergeEef ParthoensJonathan VandenbusscheKris Gevaert et al.

A1 Journal Article in BMC CANCER

2014

Defects in TAPT1, involved in axial skeletal patterning, cause a complex lethal recessive disorder of skeletal development

Sofie SymoensAileen BarnesCharlotte GistelinckFransiska MalfaitKris VleminckxBrecht GuillemynDelfien SyxWouter SteyaertEef ParthoensMartine Biervliet et al.

The unfolded-protein-response sensor IRE-1α regulates the function of CD8α⁺ dendritic cells

Fabiola OsorioSimon TavernierEik HoffmannYvan SaeysLiesbet MartensJessica VettersIris DelrueRiet De RyckeEef ParthoensPhilippe Pouliot et al.

A1 Journal Article in NATURE IMMUNOLOGY

2012

Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly

Judith VerhelstEef ParthoensBert SchepensWalter FiersXavier Saelens

A1 Journal Article in JOURNAL OF VIROLOGY

2011

Disruption of the SapM locus in Mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis

Nele FestjensPieter BogaertAnjana BatniErica HouthuysEvelyn PletsDieter VanderschaegheBram LaukensBob AsselberghEef ParthoensRiet De Rycke et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

Quinten RemijsenTom Vanden BergheEllen WirawanBob AsselberghEef ParthoensRiet De RyckeSamuel NoppenMichel DelforgeJean WillemsPeter Vandenabeele

A1 Journal Article in CELL RESEARCH

2010

Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features

Tom Vanden BergheNele VanlangenakkerEef ParthoensWies DeckersMichael DevosNele FestjensChris GuerinUT BrunkWim DeclercqPeter Vandenabeele

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

The transcriptional repressor Kaiso localizes at the mitotic spindle and is a constituent of the pericentriolar material

Adelheid SoubryKatrien StaesEef ParthoensSamuel NoppenChristophe StovePieter BogaertJolanda van HengelFrans Van Roy

A1 Journal Article in PLOS ONE

2009

Inhibition of spontaneous neutrophil apoptosis by parabutoporin acts independently of NADPH oxidase inhibition but by lipid raft-dependent stimulation of Akt

Quinten RemijsenTom Vanden BergheEef ParthoensBob AsselberghPeter VandenabeeleJean Willems

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

2008

Methods for distinguishing apoptotic from necrotic cells and measuring their clearance

Dmitri KryskoTom Vanden BergheEef ParthoensKatharina D'HerdePeter Vandenabeele

A1 Journal Article in METHODS IN ENZYMOLOGY

2007

A role for hnRNP C1/C2 and Unr in internal initiation of translation during mitosis

Bert SchepensSandrine TintonYanik BruynoogheEef ParthoensMira HaegmanRudi BeyaertSigrid Cornelis

A1 Journal Article in EMBO JOURNAL

2006

Macrophages use different internalization mechanisms to clear apoptotic and necrotic cells

Dmitri KryskoGeertrui DeneckerNele FestjensSofie GabriëlsEef ParthoensKatharina D'HerdePeter Vandenabeele

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2005

Expression and nuclear location of the transcriptional repressor kaiso is regulated by the tumor microenvironment

Adelheid SoubryJolanda van HengelEef ParthoensC COLPAERTE VAN MARCKD WALTREGNYAB REYNOLDSFrans Van Roy

A1 Journal Article in CANCER RESEARCH

Protein synthesis persists during necrotic cell death

Xavier SaelensNele FestjensEef ParthoensIsabel VanoverbergheMichaël KalaiF VAN KUPPEVELDPeter Vandenabeele

A1 Journal Article in JOURNAL OF CELL BIOLOGY