Research Explorer

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Researcher

Dorien Van Lysebetten

Awards & Distinctions

10 Results

2024

CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity

Tingting YeZifu ZhongFederica CappellessoKim DeswarteYong ChenHeleen LauwersEmily De LombaerdeMark GontsarikStefan LienenklausDorien Van Lysebetten et al.

A1 Journal Article in BIOMATERIALS

2021

Lipid-polyglutamate nanoparticle vaccine platform

Dorien Van LysebettenAlessio MalfantiKim DeswarteKaloian KoynovBianka GolbaTingting YeZifu ZhongSabah KasmiAlexander LamootYong Chen et al.

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

2019

Design and synthesis of cyclic peptide-bile acid conjugates for improving the therapeutic potential of peptide drugs

Dorien Van LysebettenAnnemieke MadderBruno De Geest

2018

A thiolactone strategy for straightforward synthesis of disulfide-linked side-chain-to-tail cyclic peptides featuring an N-terminal modification handle

Dorien Van LysebettenStefania FelissatiEirini AntonatouLieselot CarrettePieter EspeelEvelien FocquetFilip Du PrezAnnemieke Madder

A1 Journal Article in CHEMBIOCHEM

NMR structure of μ-conotoxin GIIIC : leucine 18 induces local repacking of the N-terminus resulting in reduced NaV channel potency

Peta J HarveyNyoman D KurniawanRocio K Finol-UrdanetaJeffrey R McArthurDorien Van LysebettenThomas S DashJustine M HillDavid J AdamsThomas DurekDavid J Craik

A1 Journal Article in MOLECULES

2017

Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities

Anish ParmarStephen H PriorAbhishek IyerCharlotte S VincentDorien Van LysebettenEefjan BreukinkAnnemieke MadderEdward J TaylorIshwar Singh

A1 Journal Article in CHEMICAL COMMUNICATIONS

2016

Cyclisation of peptides via a thiolactone strategy

Dorien Van LysebettenStefania FelissatiEvelien FocquetY AbdhouniPieter EspeelLieselot CarretteFilip Du PrezAnnemieke Madder

Efficient total syntheses and biological activities of two teixobactin analogues

Anish ParmarAbhishek IyerCharlotte S VincentDorien Van LysebettenStephen H PriorAnnemieke MadderEdward J TaylorIshwar Singh

A1 Journal Article in CHEMICAL COMMUNICATIONS

2015

Sequence-selective DNA recognition and enhanced cellular up-take by peptide–steroid conjugates

Yara Ruiz GarciaAbhishek IyerDorien Van LysebettenY Vladimir PabonBenoit LouageMalgorzata HoncharenkoBruno De GeestCI Edvard SmithRoger StrömbergAnnemieke Madder

A1 Journal Article in CHEMICAL COMMUNICATIONS

Stapling monomeric GCN4 peptides allows for DNA binding and enhanced cellular uptake

Abhishek IyerDorien Van LysebettenYara Ruiz GarciaBenoit LouageBruno De GeestAnnemieke Madder

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY