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Researcher
Dorien Clarisse
Profile
Projects
Publications
Activities
Awards & Distinctions
39
Results
2024
Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression
Sofie Desmet
Jonathan Thommis
Tineke Vanderhaeghen
Edmee Vandenboorn
Dorien Clarisse
Yunkun Li
Steven Timmermans
Daria Fijalkowska
Dariusz Ratman
Evelien Van Hamme
et al.
A1
Journal Article
in
MOLECULAR METABOLISM
2024
Glucocorticoid receptor signaling : intricacies and therapeutic opportunities
Dorien Clarisse
Laura Van Moortel
Chloé Van Leene
Kris Gevaert
Karolien De Bosscher
A1
Journal Article
in
TRENDS IN BIOCHEMICAL SCIENCES
2024
Unlocking therapeutic potential : exploring cross-talk among emerging nuclear receptors to combat metabolic dysfunction in steatotic liver disease
Milton Boaheng Antwi
Ariann Jennings
Sander Lefere
Dorien Clarisse
Anja Geerts
Lindsey Devisscher
Karolien De Bosscher
A2
Journal Article
in
NPJ METABOLIC HEALTH AND DISEASE
2024
2023
Crosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells
Dorien Clarisse
Stefan Prekovic
Philip Vlummens
Eleni Staessens
Karlien Van Wesemael
Jonathan Thommis
Daria Fijalkowska
Guillaume Acke
Wilbert Zwart
Ilse M. Beck
et al.
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2023
HDAC6 : one protein, two domains, diverse therapeutic opportunities : inhibitor synthesis and validation in cellular disease models
Silke Geurs
Matthias D'hooghe
Karolien De Bosscher
Dorien Clarisse
Dissertation
2023
The zinc-binding group effect : lessons from non-hydroxamic acid vorinostat analogs
Silke Geurs
Dorien Clarisse
Karolien De Bosscher
Matthias D'hooghe
A1
Journal Article
in
JOURNAL OF MEDICINAL CHEMISTRY
2023
2022
Approaches towards tissue‐selective pharmacology of the mineralocorticoid receptor
Dorien Clarisse
Lisa Deng
Karolien De Bosscher
Achim Lother
A1
Journal Article
in
BRITISH JOURNAL OF PHARMACOLOGY
2022
Carboxylic acid bioisosteres in medicinal chemistry : synthesis and properties
Kato Bredael
Silke Geurs
Dorien Clarisse
Karolien De Bosscher
Matthias D'hooghe
A1
Journal Article
in
JOURNAL OF CHEMISTRY
2022
Identification of mercaptoacetamide-based HDAC6 inhibitors via a lean inhibitor strategy : screening, synthesis, and biological evaluation
Silke Geurs
Dorien Clarisse
Freya Baele
Jorick Franceus
Tom Desmet
Karolien De Bosscher
Matthias D'hooghe
A1
Journal Article
in
CHEMICAL COMMUNICATIONS
2022
Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets
Laura Van Moortel
Jonathan Thommis
Brecht Maertens
An Staes
Dorien Clarisse
Delphine De Sutter
Claude Libert
Onno C. Meijer
Sven Eyckerman
Kris Gevaert
et al.
A1
Journal Article
in
BIOMEDICINE & PHARMACOTHERAPY
2022
The ubiquitin binding domain of HDAC6 : a key regulator of aggresomal protein disposal and new therapeutic target to combat multiple myeloma
Silke Geurs
Eleni Staessens
Dorien Clarisse
Karolien De Bosscher
Matthias D'hooghe
C3
Conference
2022
The ubiquitin binding domain of HDAC6 : a key regulator of aggresomal protein disposal and new therapeutic target to combat multiple myeloma
Silke Geurs
Dorien Clarisse
Eleni Staessens
Karolien De Bosscher
Matthias D'hooghe
C3
Conference
2022
2021
How the glucocorticoid receptor contributes to platinum-based therapy resistance in solid cancer
Dorien Clarisse
Karolien De Bosscher
Editorial material
2021
New tricks of our old friend the glucocorticoid receptor : from combating ulcerative colitis to preventing associated colorectal cancer
Dorien Clarisse
Ilse Beck
Editorial material
2021
2020
Latest perspectives on glucocorticoid-induced apoptosis and resistance in lymphoid malignancies
Dorien Clarisse
Fritz Offner
Karolien De Bosscher
A1
Journal Article
in
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
2020
Nuclear receptor crosstalk : defining the mechanisms for therapeutic innovation
Karolien De Bosscher
Sofie Desmet
Dorien Clarisse
Eva Estébanez-Perpiña
Luc Brunsveld
A1
Journal Article
in
NATURE REVIEWS ENDOCRINOLOGY
2020
2018
Effect of combining glucocorticoids with Compound A on glucocorticoid receptor responsiveness in lymphoid malignancies
Dorien Clarisse
Karlien Van Wesemael
Jan Tavernier
Fritz Offner
Ilse Beck
Karolien De Bosscher
A1
Journal Article
in
PLOS ONE
2018
Glucocorticoid resistance in multiple myeloma : mechanistic insights and therapeutic considerations
Dorien Clarisse
Karolien De Bosscher
Ilse Beck
Dissertation
2018
2017
Coregulator profiling of the glucocorticoid receptor in lymphoid malignancies
Dorien Clarisse
Jonathan Thommis
Karlien Van Wesemael
Rene Houtman
Dariusz Ratman
Jan Tavernier
Fritz Offner
Ilse Beck
Karolien De Bosscher
A1
Journal Article
in
ONCOTARGET
2017
2016
Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins
Kamila Skieterska
Ao Shen
Dorien Clarisse
Pieter Rondou
Dasiel Oscar Borroto-Escuela
Béatrice Lintermans
Kjell Fuxe
Yang Kevin Xiang
Kathleen Van Craenenbroeck
A1
Journal Article
in
CELLULAR SIGNALLING
2016
Dexamethasone induces glucocorticoid receptor (GR)-dependent mineralocorticoid receptor (MR) downregulation
Dorien Clarisse
Karolien De Bosscher
Ilse Beck
C3
Conference
2016
Selective glucocorticoid receptor-activating adjuvant therapy in cancer treatments
Nora Sundahl
Dorien Clarisse
Marc Bracke
Fritz Offner
Wim Vanden Berghe
Ilse Beck
A2
Journal Article
in
ONCOSCIENCE
2016
The mineralocorticoid receptor is involved in glucocorticoid resistance
Dorien Clarisse
Fritz Offner
Karolien De Bosscher
Ilse Beck
C3
Conference
2016
2015
Combination of dexamethasone with the selective glucocorticoid receptor modulator, Compound A, does not enhance glucocorticoid responsiveness in lymphoid malignancies
Dorien Clarisse
Fritz Offner
Marc Bracke
Karolien De Bosscher
Ilse Beck
C3
Conference
2015
Dexamethasone induces glucocorticoid receptor (GR)-dependent mineralocorticoid receptor (MR) downregulation
Dorien Clarisse
Karolien De Bosscher
Ilse Beck
C3
Conference
2015
Dexamethasone induces glucocorticoid receptor (GR)-dependent mineralocorticoid receptor (MR) downregulation
Dorien Clarisse
Karolien De Bosscher
Ilse Beck
C3
Conference
2015
Pro-inflammatory cell stress in muscle cells is directed by NFAT5
dr. Sandrine Herbelet
Jens Schmidt
Olivier De Wever
Eline Nys
Laurens Weynants
Dorien Clarisse
Glenn Vergauwen
Boel De Paepe
Jan De Bleecker
C3
Conference
2015
2014
Cofactor profiling of the glucocorticoid receptor from a cellular environment
Sofie Desmet
Lien Dejager
Dorien Clarisse
Jonathan Thommis
Diana Melchers
Niek Bastiaensen
Rob Ruijtenbeek
Ilse Beck
Claude Libert
Renée Houtman
et al.
Bookchapter
in
Steroid receptors : methods and protocols
2014
Determining the cofactor profile of the glucocorticoid receptor in lymphoid malignancies using MARCoNI
Dorien Clarisse
Sofie Desmet
Jonathan Thommis
Ilse Beck
Karolien De Bosscher
C3
Conference
2014
Determining the coregulator profile of the endogenous glucocorticoid receptor in lymphoid malignancies using MARCoNI
Dorien Clarisse
Dariusz Ratman
Sofie Desmet
Jonathan Thommis
René Houtman
Karolien De Bosscher
Ilse Beck
C3
Conference
2014
The increasing complexity of glucocorticoid receptor signaling and regulation
Sofie Desmet
Ilse Beck
Nadia Bougarne
Dorien Clarisse
Julie Deckers
Dariusz Ratman
Jan Tavernier
Karolien De Bosscher
A2
Journal Article
in
PROCEEDINGS OF THE BELGIAN ROYAL ACADEMIES OF MEDICINE
2014
2013
Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation
Ilse Beck
Zuzanna Drebert
Ruben Hoya-Arias
Ali A Bahar
Michael Devos
Dorien Clarisse
Sofie Desmet
Nadia Bougarne
Bart Ruttens
Valerie Gossye
et al.
A1
Journal Article
in
PLOS ONE
2013
Mitogen- and stress-activated protein kinase 1 (MSK1) regulates glucocorticoid response element (GRE) promoter activity in a glucocorticoid concentration-dependent manner
Ilse Beck
Dorien Clarisse
Nadia Bougarne
Sam Okret
Guy Haegeman
Karolien De Bosscher
C3
Conference
2013
Mitogen- and stress-activated protein kinase 1 MSK1 regulates glucocorticoid response element promoter activity in a glucocorticoid concentration-dependent manner
Ilse Beck
Dorien Clarisse
Nadia Bougarne
Sam Okret
Guy Haegeman
Karolien De Bosscher
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACOLOGY
2013
2012
Functional relevance of the KLHL12-mediated D4 dopamine receptor ubiquitination
Kamila Skieterska
Pieter Rondou
Dasiel Oscar Borroto-Escuela
Dorien Clarisse
Béatrice Lintermans
Guy Haegeman
Kjell Fuxe
Kathleen Van Craenenbroeck
C3
Conference
2012
On the track of function of KLHL12-mediated dopamine D4 receptor ubiquitination
Kamila Skieterska
Pieter Rondou
Dasiel Oscar Borroto-Escuela
Dorien Clarisse
Béatrice Lintermans
Guy Haegeman
Kjell Fuxe
Kathleen Van Craenenbroeck
C3
Conference
2012
On the track of function of KLHL12-mediated dopamine D4 receptor ubiquitination
Kamila Skieterska
Pieter Rondou
Dasiel Oscar Borroto-Escuela
Dorien Clarisse
Béatrice Lintermans
Guy Haegeman
Kjell Fuxe
Kathleen Van Craenenbroeck
C3
Conference
2012
The Fukui matrix : Fukui functions exposed!
Patrick Bultinck
Guillaume Acke
Dorien Clarisse
Dimitri Van Neck
Paul W Ayers
C3
Conference
2012
2011
The Fukui matrix : a simple approach to the analysis of the Fukui function and its positive character
Patrick Bultinck
Dorien Clarisse
Paul W Ayers
Ramon Carbo-Dorca Carre
A1
Journal Article
in
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
2011