Research Explorer

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Researcher

Dirk Van Haver

Publications & Research Data

Awards & Distinctions

39 Results

2009

Development of Analogues of 1 alpha,25-Dihydroxyvitamin D-3 with Biased Side-Chain Orientation: C20 Methylated Des-C,D-homo Analogues

Freek VrielynckDirk Van HaverMaurits VandewalleLieve VerlindenAnnemieke VerstuyfRoger BouillonGianluca CrocePierre De Clercq

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

2007

Mechanism and potential of the growth-inhibitory actions of vitamin D and analogs

G EELENC GYSEMANSL VERLINDENE VANOIRBEEKPierre De ClercqDirk Van HaverC MATHIEUR BOUILLONA VERSTUYF

A1 Journal Article in CURRENT MEDICINAL CHEMISTRY

The development of CD-ring modified analogs of 1 alpha,25-dihydroxyvitamin D

Pierre De ClercqFrederik De BuysserGarrett MinneW SCHEPENSFreek VrielynckDirk Van HaverM VANDEWALLEA VERSTUYFR BOUILLON

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

2006

Asymmetric synthesis of (7aS)-7a-methyl-4,5,7,7a-tetrahydro-1H-indene-2,6-dione and useful derivatives thereof

Samuël DeminDirk Van HaverPierre De Clercq

A1 Journal Article in MOLECULES

Synthesis of spiro[4.5] decane CF-ring analogues of 1 alpha,25-dihydroxyvitamin D-3

Wim SchepensDirk Van HaverMaurits VandewalleR BOUILLONA VERSTUYFPierre De Clercq

A1 Journal Article in ORGANIC LETTERS

2004

Biological activity and conformational analysis of C20 and C14 epimers of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs

Pierre De ClercqIbrahim MuradLing-Jie GaoYong-Jun ChenDirk Van HaverMaurits VandewalleAnnemieke VerstuyfLieve VerlindenChristel VerbovenRoger Bouillon

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1 α,25-dihydroxyvitamin D3 : cis-perhydrindane CE-ring analogues

Samuël DeminDirk Van HaverMaurits VandewallePierre De ClercqR BouillonA Verstuyf

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1 α,25-dihydroxyvitamin D3 : spiro[5.5]undecane CF-ring analogues

Wim SchepensDirk Van HaverMaurits VandewallePierre De ClercqR BouillonA Verstuyf

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

2003

Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity

L VerlindenS VerstuyfC VerbovenG EelenC De RanterLJ GaoY ChenIbrahim MuradM ChoiK Yamamoto et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis and binding affinity studies of muscarinic receptor antagonists related to dehydrohimbacine

LJ GaoGunther Van CauwenbergeNoël HostenDirk Van HaverM WaelbroeckPierre De Clercq

A1 Journal Article in ARKIVOC

Synthesis, biological activity, and conformational analysis of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs

YJ CHENLJ GAOIbrahim MuradA VERSTUYFL VERLINDENC VERBOVENR BOUILLOND VITERBOM MILANESIODirk Van Haver et al.

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

2002

A novel short convergent entry into himbacine derivatives

G Van CauwenbergeLJ GaoDirk Van HaverM MilanesioD ViterboPierre De Clercq

A1 Journal Article in ORGANIC LETTERS

An intramolecular Furan-Diene Diels-Alder approach to 11-oxo 10 alpha-steroids

Sandra ClaeysDirk Van HaverPierre De ClercqM MILANESIOD VITERBO

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Evaluation of a two-stage screening procedure in the combinatorial search for serine protease-like activity

Annemieke MadderL LIHilde De MuynckNadia FarcyDirk Van HaverFranky FantG VANHOENACKERPatrick SandraAP DAVISPierre De Clercq

A1 Journal Article in JOURNAL OF COMBINATORIAL CHEMISTRY

Synthesis and affinity studies of himbacine derived muscarinic receptor antagonists

LJ GAOM WAELBROECKSven HofmanDirk Van HaverM MILANESIOD VITERBOPierre De Clercq

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

2001

A short intramolecular Diels-Alder route to himbacine derivatives

Sven HofmanLJ GAOHilde Van DingenenN HOSTENDirk Van HaverPierre De ClercqM MILANESIOD VITERBO

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Development of analogues of 1 alpha,25-dihydroxyvitamin D-3 with biased side chain orientation : methylated des-C,D-homo analogues

Stefan GabrielsDirk Van HaverMaurits VandewallePierre De ClercqA VERSTUYFR BOUILLON

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

2000

Biological activity of CD-ring modified 1 alpha,25-dihydroxyvitamin D analogues : C-ring and five-membered D-ring analogues

A VERSTUYFL VERLINDENE VAN ETTENL SHIYS WUChristiaan D'HalleweynDirk Van HaverGD ZHUYJ CHENXM ZHOU et al.

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

1999

On the unexpected stereochemical outcome of the magnesium in methanol : conjugate reduction of an exocyclic alpha,beta-unsaturated ester

Stefan GabrielsDirk Van HaverMaurits VandewallePierre De ClercqDavide Viterbo

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis, biological activity, and conformational analysis of four seco-D-15,19-bisnor-1 alpha,25-dihydroxyvitamin D analogues, diastereomeric at C17 and C20

XM ZHOUGD ZHUDirk Van HaverMaurits VandewallePierre De ClercqA VERSTUYFR BOUILLON

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

1998

On the use of volume maps in the conformational analysis of vitamin D analogs

Dirk Van HaverPierre De Clercq

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1997

Mechanism of esterification of 1,3-dimethylamino alcohols by N-acetylimidazole in acetonitrile and the influence of alkyl and geminal dialkyl substitution upon the rate

Annemieke MadderS SEBASTIANDirk Van HaverPierre De ClercqH MASKILL

A1 Journal Article in JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2

Synthesis of CD-ring modified 1 alpha,25-dihydroxy vitamin D analogues : five-membered D-ring analogues

W YongS LingChristiaan D'HalleweynDirk Van HaverPierre De ClercqMaurits Vandewalle

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1994

11-fluoro-1-alpha-hydroxyvitamin D-3 : the quest for experimental evidence of the folded vitamin-D conformation

GD ZHUDirk Van HaverH JURRIAANSPierre De Clercq

A1 Journal Article in TETRAHEDRON

Intramolecular diels-alder reaction of 8-trifluoromethyl-1,3,8-nonatrienes : an access to angular trifluoromethylated hydrindenes

GD ZHUBart Van LanckerDirk Van HaverPierre De Clercq

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1993

Chemical properties of the natural neurotoxin of Lathyrus sativus 3-N-oxalyl-2,3-diamino-propanoic acid (β-ODAP), its nontoxic 2-N-oxalyl isomer, and its hydrolysis product 2,3-diamino-propanoic acid (DAPRO) by 1H- and 13C-NMR spectroscopy

André De BruynDirk Van HaverFernand LambeinBM Abegaz

A2 Journal Article in NATURAL TOXINS

1992

Synthesis of (C-11)-substituted analogues of 1α,25-dihydroxyvitamin D3

Christiaan D'HalleweynDirk Van HaverJohan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1989

The synthesis of 4 desoxy-2-azapodophyllotoxins

Johan Van der EyckenJean-Paul BosmansDirk Van HaverMaurits VandewalleA HulkenbergW VeermanR Nieuwenhuizen

A1 Journal Article in TETRAHEDRON LETTERS

1988

Drug distribution in dog brain studied by positron emission tomography

P AgonR BraeckmanDirk Van HaverH DenutteP GoethalsH DoncheFranklin VermeulenJoris DemanJean Kaufman

A1 Journal Article in BIOPHARMACEUTICS & DRUG DISPOSITION

1985

Production of C-11-labeled quinidine and tamoxifen

Dirk Van HaverTineke Van de WalleGuido SlegersCarlo Vandecasteele

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Routine production of 2-deoxy-D-[1-11C]glucose : an alternative

Dirk Van HaverN.A. RabiMaurits VandewalleP GoethalsCarlo Vandecasteele

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Routine production of H11CN and [11C]-1-Aminocyclopentanecarboxylic acid

JOHAN SAMBRECarlo VandecasteelePatrick GoethalsN.A. RabiDirk Van HaverGuido Slegers

A1 Journal Article in INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES

1983

Remote-controlled production of 11C-antipyrine

Dirk Van HaverPierre De ClercqMaurits VandewalleTony VandewalleCarlo Vandecasteele

1982

Remote-controlled production of [11C]antipyrine

Dirk Van HaverPierre De ClercqT Van de WalleC Vandecasteele

A1 Journal Article in INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES

1977

1H NMR spectral parameters and configurational assignment of the isomeric 1,4-diacetoxy-2-t-butyl-3-methylcyclopentanes

Dirk Van HaverM SamsonMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

Conformational analysis of prostaglandins F1 based on proton nuclear magnetic resonance spectral data

Pierre De ClercqM SamsonDirk TavernierDirk Van HaverMaurits Vandewalle

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

1975

Cyclopentanones : XII. An alternative synthesis of prostaglandins involving catalytic hydrogenation of 2, 3-dialkyl-4-dihydroxy-2-cyclopentenones

R. CoenPierre De ClercqDirk Van HaverMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIÉTÉS CHIMIQUES BELGES

1974

Configurational assignment and 1H-NMR spectral parameters of the isomeric 1,4-diacetoxy-2,3-dimethylcyclopentanes

Dirk Van HaverDirk TavernierMarc AnteunisMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

Cyclopentanones—VIII : stereochemistry of the lithium-liquid ammonia reduction of 2,3-dialkyl-4-hydroxy-2-cyclopentenones

Pierre De ClercqDirk Van HaverDirk TavernierM Vandewalle

A1 Journal Article in TETRAHEDRON