Research Explorer

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Researcher

Dieter Tulkens

Publications & Research Data

Awards & Distinctions

10 Results

2026

A CRISPR-based Xenopus tropicalis model for retroperitoneal liposarcoma with genetic control over the dedifferentiation process

Marthe BoelensDieter TulkensArne ChristiaensWout HoubartSuzan DemuynckDavid CreytensKris Vleminckx

2023

Mutations in the histone methyltransferase Ezh2 drive context-dependent leukemia in Xenopus tropicalis

Dieter TulkensMarthe BoelensThomas NaertMarjolein CarronSuzan DemuynckSylviane DewaeleGert Van IsterdaelDavid CreytensTim PietersSteven Goossens et al.

A1 Journal Article in LEUKEMIA

2022

Engraftment of allotransplanted tumor cells in adult rag2 mutant Xenopus tropicalis

Dieter TulkensDionysia DimitrakopoulouMarthe BoelensTom Van NieuwenhuysenSuzan DemuynckWendy ToussaintDavid CreytensPieter Van VlierbergheKris Vleminckx

A1 Journal Article in CANCERS

Identifying and characterizing EZH2 as a druggable dependency factor for desmoid tumors in a genetic Xenopus tropicalis model for Gardner's Syndrome

Thomas NaertDieter TulkensTom Van NieuwenhuysenJoanna PrzybylSuzan DemuynckMushriq Al-JazraweMatt van de RijnBenjamin AlmanKim De LeenheerPaul Coucke et al.

Uncovering novel cancer driver genes using CRISPR/Cas9 multiplexing in Xenopus tropicalis

Dieter TulkensKris VleminckxPieter Van Vlierberghe

2021

CRISPR-SID : identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping

Thomas NaertDieter TulkensTom Van NieuwenhuysenJoanna PrzybylSuzan DemuynckMatt van de RijnMushriq Al-JazraweBenjamin A. AlmanPaul CouckeKim De Leeneer et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2020

A combined RNA preservation and extraction protocol for gene expression studies in cacao beans

Jocelyn De WeverDieter TulkensJan VerwaerenHelena EveraertHayley RottiersKoen DewettinckSteve LefeverKathy Messens

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos

Thomas NaertDieter TulkensNicole A. EdwardsMarjolein CarronNikko-Ideen ShaidaniMarcin WlizlaAnnekatrien BoelSuzan DemuynckMarko E. HorbPaul Coucke et al.

A1 Journal Article in SCIENTIFIC REPORTS

RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis

Thomas NaertDionysia DimitrakopoulouDieter TulkensSuzan DemuynckMarjolein CarronRivka NoelandersLiza EeckhoutGert Van IsterdaelDieter DeforceChristian Vanhove et al.

A1 Journal Article in ONCOGENE

2019

Xenopus tropicalis : joining the armada in the fight against blood cancer

Dionysia DimitrakopoulouDieter TulkensPieter Van VlierbergheKris Vleminckx

A1 Journal Article in FRONTIERS IN PHYSIOLOGY