Research Explorer

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Researcher

Denis De Keukeleire

Publications & Research Data

Awards & Distinctions

240 Results

2021

Relevance of hop terroir for beer flavour

Ann Van HolleHilde MuylleGeert HaesaertDirk NaudtsDenis De KeukeleireIsabel Roldán-RuizAnita Van Landschoot

A1 Journal Article in JOURNAL OF THE INSTITUTE OF BREWING

2019

Single nucleotide polymorphisms and biochemical markers as complementary tools to characterize hops (Humulus lupulus L.) in brewing practice

Ann Van HolleHilde MuylleTom RuttinkAnita Van LandschootGeert HaesaertDirk NaudtsDenis De KeukeleireIsabel Roldán-Ruiz

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

2017

The brewing value of Amarillo hops (Humulus lupulus L.) grown in northwestern USA : a preliminary study of terroir significance

Ann Van HolleAnita Van LandschootIsabel Roldán-RuizDirk NaudtsDenis De Keukeleire

A1 Journal Article in JOURNAL OF THE INSTITUTE OF BREWING

2015

Comparison of the analytical profiles of volatiles in single-hopped worts and beers as a function of the hop variety

Michael DreselTatiana PraetFilip Van OpstaeleAnn Van HolleDirk NaudtsDenis De KeukeleireLuc De CoomanGuido Aerts

A2 Journal Article in BREWING SCIENCE

Evaluation of glycerol profiles in sugarcane spirits (cachacas)

Andre C GarciaFelipe AT SerafimDenis De KeukeleireDouglas W Franco

A1 Journal Article in JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

2013

Characterisation of fresh and aged single-hop beers via hop oil constituents fingerprinting and sensory assessment

Filip Van OpstaeleAnn Van HolleJan Van NieuwenhoveDirk NaudtsDenis De KeukeleireGuido AertsLuc De Cooman

From wort to beer : the evolution of hoppy aroma of single hop beers produced by early kettle hopping, late kettle hopping and dry hopping

Michael DreselTatiana PraetFilip Van OpstaeleAnn Van HolleJan Van NieuwenhoveDirk NaudtsDenis De KeukeleireGuido AertsLuc De Cooman

Investigation of the impact of the hop variety and the hopping technology on the analytical volatile profile of single-hopped worts and beers

Michael DreselFilip Van OpstaeleTatiana PraetBarbara Jaskula-GoirisAnn Van HolleDirk NaudtsDenis De KeukeleireLuc De CoomanGuido Aerts

A2 Journal Article in BREWING SCIENCE

Metabolism of hop-derived bitter acids

Ko CattoorMichael DreselLies De BockKoen BousseryJan Van BocxlaerJean Paul RemonDenis De KeukeleireDieter DeforceThomas HofmannArne Heyerick

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

2012

Analytical and sensory assessment of the flavour stability impact of dry-hopping in single-hop beers

Yvan BorremansFilip Van OpstaeleAnn Van HolleJan Van NieuwenhoveBarbara Jaskula-GoirisJessika De ClippeleerDirk NaudtsDenis De KeukeleireLuc De CoomanGuido Aerts

Fingerprinting of hop oil constituents and sensory evaluation of the essential oil of hop pellets from pure hop varieties and single-hop beers derived thereof

Filip Van OpstaeleYvan BorremansAnn Van HolleJan Van NieuwenhovePieter De PaepeDirk NaudtsDenis De KeukeleireGuido AertsLuc De Cooman

2011

Bioavailability of hop-derived iso-α-acids and reduced derivatives

Ko CattoorJean Paul RemonKoen BousseryJan Van BocxlaerMarc BrackeDenis De KeukeleireDieter DeforceArne Heyerick

A1 Journal Article in FOOD & FUNCTION

2010

A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts

R ErkkolaS VervarckeStijn VansteelandtP RompottiDenis De KeukeleireArne Heyerick

A1 Journal Article in PHYTOMEDICINE

Cloning and molecular analysis of HlbZip1 and HlbZip2 transcription factors putatively involved in the regulation of the lupulin metabolome in hop (Humulus lupulus L.)

Jaroslav MatouśekTomáś KocábekJosef PatzakJan StehlikZoltan FůssyKarel KroftaArne HeyerickIsabel Roldán-RuizLina MaloukhDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Development of a high-throughput LC/APCI-MS method for the determination of thirteen phytoestrogens including gut microbial metabolites in human urine and serum

Ciska WynsSelin BolcaDenis De KeukeleireArne Heyerick

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Disposition of hop prenylflavonoids in human breast tissue

Selin BolcaJinghu LiDejan NikolicNathalie RochePhillip BlondeelSam PossemiersDenis De KeukeleireMarc BrackeArne HeyerickRichard B Van Breemen et al.

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

Disposition of soy isoflavones in normal human breast tissue

Selin BolcaMireia Urpi-SardaPhillip BlondeelNathalie RocheLynn VanhaeckeSam PossemiersNawaf Al-MaharikNigel BottingDenis De KeukeleireMarc Bracke et al.

A1 Journal Article in AMERICAN JOURNAL OF CLINICAL NUTRITION

Transport of hop bitter acids across intestinal Caco-2 cell monolayers

Ko CattoorMarc BrackeDieter DeforceDenis De KeukeleireArne Heyerick

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

2009

A prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts

Alvin IbarraSophie LafayArne HeyerickStefaan VervarckeHerman Depyperemarc brackeDenis De Keukeleire

Cloning and molecular analyses of hop transcription factors

Jaroslav MatoušekThomas KocábekJosef ŠkopekL OrctováJ StehlikZoltan FüssyJosef PatzakKarel KroftaLina MaloukhIsabel Roldán-Ruiz et al.

Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17beta-estradiol equivalents

Selin BolcaCiska WynsSam PossemiersHerman DepypereDenis De KeukeleireMarc BrackeWilly VerstraeteArne Heyerick

A1 Journal Article in JOURNAL OF NUTRITION

Hop (Humulus lupulus)-Derived Bitter Acids as Multipotent Bioactive Compounds

Marjan Van CleemputKo CattoorKarolien De BosscherGuy HaegemanDenis De KeukeleireArne Heyerick

A1 Journal Article in Journal of Natural Products

Hop bitter acids efficiently block inflammation independent of GRα, PPARα, or PPARγ

Marjan Van CleemputArne HeyerickClaude LibertKatrien SwertsJan PhilippéDenis De KeukeleireGuy HaegemanKarolien De Bosscher

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

Identification of full-length cDNA sequences of hop (Humulus lupulus L.) candidate genes of the prenylflavonid pathway

Lina MaloukhJelle De KeukeleireJaroslav MatousekPaul D MatthewsAxel SchwekendiekArne HeyerickDenis De KeukeleireErik Van BockstaeleIsabel Roldán-Ruiz

Microbial activation of mixtures of isoflavones, prenylflavonoids and lignans

Selin BolcaEllen EeckhautArne HeyerickDenis De KeukeleireHerman DepypereMarc BrackeTom Van de WieleWilly Verstraete

Microbial and dietary factors associated with the Equol and 8-prenylnaringenin producer phenotypes

Selin BolcaSam PossemiersWilly VerstraeteTom Van de WieleArne HeyerickDenis De KeukeleireInge HuybrechtsStefaan De HenauwHerman DepypereMarc Bracke

Production of phytoestrogens from hops by intestinal bacteria: from discovery to product development

Sam PossemiersWilly Verstraete

2008

Cellular uptake of soy-derived phytoestrogens in vitro and in human whole blood

Julie Maubachmarc brackeHerman DepypereDenis De KeukeleireArne Heyerick

A2 Journal Article in Journal of Pre-Clinical and Clinical Research

Development of a high-throughput LC-APCI-MS method for the determination of 13 phytoestrogens (including gut microbial metabolites) in human urine and serum

Ciska WynsSelin BolcaDenis De KeukeleireArne Heyerick

Eubacterium limosum activates isoxanthohumol from hops (Humulus lupulus L.) into the potent phytoestrogen 8-prenylnaringenin in vitro and in rat intestine

Sam PossemiersSylvie RABOTJuan carlos ESPINAurelia BRUNEAUCatherine PHILIPPEAntonio GONZALEZ-SARRIASArne HeyerickFrancisco TOMAS-BARBERANDenis De KeukeleireWilly Verstraete

A1 Journal Article in JOURNAL OF NUTRITION

In-vitro and in-vivo evidence for the anti-inflammatory activity of hop bitter acids in mouse

Marjan Van CleemputArne HeyerickClaude LibertDenis De KeukeleireGuy HaegemanKarolien De Bosscher

Metabolism of the lignan macromolecule into enterolignans in the gastrointestinal lumen as determined in the simulator of the human intestinal microbial ecosystem

Ellen EeckhautKarin StruijsSam PossemiersJean-Paul VinckenDenis De KeukeleireWilly Verstraete

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Plant polyphenolics as anti-invasive cancer agents

Marc BrackeBarbara VanhoeckeLara DeryckeSelin BolcaSam PossemiersArne HeyerickChristian StevensDenis De KeukeleireHerman DepypereWilly Verstraete et al.

A1 Journal Article in ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY

Removal of some polycyclic aromatic hydrocarbons from petrochemical wastewater using low-cost adsorbents of natural origin

Rudy CrisafullyMaria Aparecida L. MilhomeRivelino M. CavalcanteEdilberto R. SilveiraDenis De KeukeleireRonaldo F. Nascimento

A1 Journal Article in BIORESOURCE TECHNOLOGY

Simultaneous analysis of riboflavin and aromatic amino acids in beer using fluorescence and multivariate calibration methods

Ewa SikorskaAnna Glisuzynska-SwigloMalgorzata Insinska-RakIgor KhmelinskiiDenis De KeukeleireMarek Sikorski

A1 Journal Article in ANALYTICA CHIMICA ACTA

The prenylated chalcone xanthohumol induces unfolded protein response, autophagy, and cell death in breast cancer cells by proteasome inhibition

Barbara VanhoeckeMireille Van GeleWim MartinetAnne-Sophie Vercoutter-EdouartSofie LustDelphine DebruyneDenis De KeukeleireFritz Offnermarc bracke

Treatment of PC-3 and DU145 prostate cancer cells by prenylflavonoids from hop (Humulus lupulus L.) induces a caspase-independent form of cell death

L DelmulleTom Vanden BergheDenis De KeukeleirePeter Vandenabeele

A1 Journal Article in PHYTOTHERAPY RESEARCH

2007

Constitutive expression of a grapevine stilbene synthase gene in transgenic hop (Humulus lupulus L.) yields resveratrol and its derivatives in substantial quantities

A SCHWEKENDIEKO SPRINGArne HeyerickB PICKELNT PITSCHF PESCHKEDenis De KeukeleireG WEBER

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Discrimination of beer flavours by analysis of volatiles using the mass spectrometer as an electronic nose

E SIKORSKAJ CHMIELEWSKIT GORECKII KHMELINSKIIM SIKORSKIDenis De Keukeleire

A1 Journal Article in JOURNAL OF THE INSTITUTE OF BREWING

HIMyb3, a putative regulatory factor in hop (Humulus lupulus L.), shows diverse biological effects in heterologous transgenotes

J MATOUSEKT KOCABEKJ PATZAKJ SKOPEKL MALOUKHArne HeyerickZ FUSSYIsabel Roldán-RuizDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Microbial and dietary factors are associated with the equol producer phenotype in healthy postmenopausal women

Selin BolcaSam PossemiersAnnelies HerregatInge HuybrechtsArne HeyerickStephanie De VrieseMarian VerbruggenHerman DepypereDenis De KeukeleireMarc Bracke et al.

A1 Journal Article in JOURNAL OF NUTRITION

Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women

Selin BolcaSam PossemiersVeerle MaervoetInge HuybrechtsArne HeyerickStefaan VervaeckeHerman DepypereDenis De KeukeleireMarc BrackeStefaan De Henauw et al.

A1 Journal Article in BRITISH JOURNAL OF NUTRITION

Microbial and dietary factors associated with the equaol and 8-prenylnaringenin poducer phenotypes

Selin BolcaSam PossemiersArne HeyerickInge HuybrechtsHerman DepypereDenis De KeukeleireMarc BrackeStefaan De HenauwWilly VerstraeteTom Van de Wiele

Relevance of organic farming and effect of climatological conditions on the formation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol in hop (Humulus lupulus L.)

Jelle De KeukeleireI JANSSENSArne HeyerickG GHEKIEREJ CAMBIEIsabel Roldán-RuizErik Van BockstaeleDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Withaferin A strongly elicits I kappa B kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity

Mary KailehWim Vanden BergheArne HeyerickJ HORIONJ PIETTEClaude LibertDenis De KeukeleireT ESSAWIGuy Haegeman

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2006

A first prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts

Arne HeyerickS VERVARCKEHerman Depyperemarc brackeDenis De Keukeleire

A1 Journal Article in MATURITAS

Anti-proliferative properties of prenylated flavonoids from hops (Humulus lupulus L.) in human prostate cancer cell lines

L DELMULLEA BELLAHCENEW DHOOGEFrank ComhaireF ROELENSK HUVAEREArne HeyerickV CASTRONOVODenis De Keukeleire

A1 Journal Article in PHYTOMEDICINE

ARE PHYTOESTROGENS OF ANY HELP

Herman DepypereMarc BrackeBarbara VanhoeckeDenis De KeukeleireArne HeyerickSelin BolcaWilly Verstraete

Bioavailability of phytoestrogens from soy and hops

Selin BolcaSam PossemiersArne HeyerickDenis De KeukeleireHerman DepypereMarc BrackeInge HuybrechtsStefaan De HenauwWilly Verstraete

Effects of xanthohumol on human breast cancer cells in vitro : cellular and molecular mechanisms associated with invasion, stress and apoptosis

Barbara VanhoeckeHerman DepypereDenis De Keukeleire

Efficient extraction of High-Quality total RNA from various hop tissues (Humulus lupulus L.)

Jelle De KeukeleireIsabel Roldán-RuizErik Van BockstaeleArne HeyerickDenis De Keukeleire

A1 Journal Article in PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

Exploring the 8-PN producer phenotype: an intervention trial with 50 healthy post-menopausal Caucasian women

Selin BolcaSam PossemiersVeerle MaervoetArne HeyerickDenis De KeukeleireHerman DepypereMarc BrackeInge HuybrechtsTom Van de WieleWilly Verstraete

Exploring the equol producer phenotype: an intervention trial with 100 healthy post-menoapausal Caucasian women

Selin BolcaSam PossemiersAnnelies HerregatArne HeyerickDenis De KeukeleireHerman DepypereMarc BrackeInge HuybrechtsStefaan De HenauwTom Van de Wiele et al.

Flavin-induced photodecomposition of sulfur-containing amino acids is decisive in the formation of beer lightstruck flavor

Kevin HuvaereML ANDERSENMichael StormeJan Van BocxlaerLH SKIBSTEDDenis De Keukeleire

A1 Journal Article in PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Metabolism of the food-associated carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine by human intestinal microbiota

Lynn VanhaeckeNathalie Van HoofW VAN BRABANDTBram SoenenArne HeyerickNorbert De KimpeDenis De KeukeleireWilly VerstraeteTom Van de Wiele

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Monitoring beer during storage by fluorescence spectroscopy

E SIKORSKAT GORECKIIV KHMELINSKIIM SIKORSKIDenis De Keukeleire

A1 Journal Article in FOOD CHEMISTRY

Sequence analysis of a "true" chalcone synthase (chs_H1) oligofamily from hop (Humulus lupulus L.) and PAP1 activation of chs_H1 in heterologous systems

J MATOUSEKL VRBAJ SKOPEKL ORCTOVAK PESINAArne HeyerickD BAULCOMBEDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The prenylflavonoid isoxanthohumol from hops (Humulus lupulus L.) is activated into the potent phytoestrogen 8-prenylnaringenin in vitro and in the human intestine

Sam PossemiersSelin BolcaCharlotte GrootaertArne HeyerickKarel DecroosWillem DhoogeDenis De KeukeleireS RABOTWilly VerstraeteTom Van de Wiele

A1 Journal Article in JOURNAL OF NUTRITION

2005

A safety study of oral tangeretin and xanthohumol administration to laboratory mice

Barbara VanhoeckeFEMKE DELPORTEEva Van BraeckelArne HeyerickHerman DepypereM NUYTINCKDenis De Keukeleiremarc bracke

A1 Journal Article in IN VIVO

Activation of proestrogens from hops (Humulus lupulus L.) by intestinal microbiota; Conversion of isoxanthohumol into 8-prenylnaringenin

Sam PossemiersArne HeyerickVeerle RobbensDenis De KeukeleireWilly Verstraete

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antiinvasive effect of xanthohumol, a prenylated chalcone present in hops (Humulus lupulus L.) and beer

Barbara VanhoeckeLara DeryckeV VAN MARCKHerman DepypereDenis De Keukeleiremarc bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Cloning and molecular analysis of the regulatory factor HiMyb1 in hop (Humulus lupulus L.) and the potential of hop to produce bioactive prenylated flavonoids

J MATOUSEKL VRBAP NOVAKJ PATZAKJelle De KeukeleireJ SKOPEKArne HeyerickIsabel Roldán-RuizDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Estrogenic activity of a polyphenolic extract of the leaves of Epimedium brevicornum

An De NaeyerV POCOCKS MILLIGANDenis De Keukeleire

A1 Journal Article in FITOTERAPIA

Fate of flavins in sensitized photodegradation of isohumulones and reduced derivatives: studies on formation of radicals via EPR combined with detailed product analyses

Arne HeyerickKevin HuvaereDenis De KeukeleireMDE FORBES

A1 Journal Article in PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

New anti-invasive compounds: Results from the Indo-Belgian screening program

Barbara VanhoeckeHerman DepypereA DE BEYTERSK SHARMAVS PARMARDenis De Keukeleiremarc bracke

A1 Journal Article in PURE AND APPLIED CHEMISTRY

Photooxidative degradation of beer bittering principles: A key step on the route to lightstruck flavor formation in beer

Kevin HuvaereML ANDERSENLH SKIBSTEDArne HeyerickDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Phytoestrogens in Cancer Prevention: Characterization and Beneficial Effects of Kurarinone, a New Flavanone and a Major Phytoestrogen Constituent of Sophora flavescens Ait., Chapter 25 in: Phytopharmaceuticals in Cancer Chemoprevention, Debasis Bagchi & Harry G. Preuss (eds), CRC Press, Boca Raton, Florida, USA, 2005 (ISBN: 0-8493-1560-3)

Ann DE NAEYERWim VANDEN BERGHEDenis De KeukeleireGuy Haegeman

Bookchapter in Phytopharmaceuticals in Cancer Chemoprevention

Prenylflavonoids account for intriguing biological activities of hops

Denis De KeukeleireArne Heyerick

Regioselective synthesis and estrogenicity of (+/-)-8-alkyl-5,7-dihydroxy-4-(4-hydroxyphenyl)-3,4-dihydrocoumarins

Frederik RoelensKevin HuvaereWillem DhoogeMarjan Van CleemputF COMHAIREDenis De Keukeleire

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Screening for genes involved in the biosynthesis of prenylated chalcones in hops (Humulus lupulus L.).

Jelle De KeukeleireIsabel Roldán-RuizErik Van BockstaeleArne HeyerickDenis De Keukeleire

2004

Analysis of benzodiazepines in dynamically coated capillaries by CE-DAD, CE-MS and CE-MS2

G VANHOENACKERF DE L'ESCAILLEDenis De KeukeleirePatrick Sandra

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Analysis of iso-alpha-acids and reduced iso-alpha-acids in beer by direct injection and liquid chromatography with ultraviolet absorbance detection or with mass spectrometry

G VANHOENACKERDenis De KeukeleirePatrick Sandra

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Cellular activities related to growth and invasion: targets for flavonoids

Barbara VanhoeckeHerman DepypereDenis De KeukeleireMarc Bracke

Bookchapter in Recent research developments in cell science

De lichtsmaak in bier

Kevin HuvaereDenis De Keukeleire

Distribution of soy-derived phytoestrogens in human breast tissue and biological fluids

J MAUBACHHerman DepypereJan GoemanJohan Van der EyckenArne Heyerickmarc brackePhillip BlondeelDenis De Keukeleire

A1 Journal Article in OBSTETRICS AND GYNECOLOGY

Dynamic coating for fast and reproducible determination of basic drugs by capillary electrophoresis with diode-array detection and mass spectrometry

G VANHOENACKERF DE L'ESCAILLEDenis De KeukeleirePatrick Sandra

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Estrogenic and anticarcinogenic properties of kurarinone, a lavandulyl flavanone from the roots of Sophora flavescens

An De NaeyerWim Vanden BergheV POCOCKS MILLIGANGuy HaegemanDenis De Keukeleire

A1 Journal Article in JOURNAL OF NATURAL PRODUCTS

Fluorescence spectroscopy for characterization and differentiation of beers

E SIKORSKAT GORECKIIV KHMELINSKIIM SIKORSKIDenis De Keukeleire

A1 Journal Article in JOURNAL OF THE INSTITUTE OF BREWING

Influence and effect of thermal treatment in elaboration of regional wood extracts for cachaca

JOS CAMPOSFWB DE AQUINORF DO NASCIMENTOJGM DA COSTADenis De KeukeleireARS DE CASIMIRO

A1 Journal Article in JOURNAL OF FOOD COMPOSITION AND ANALYSIS

New trends in advanced hopping, part 1 : application of pre-isomerized hop extracts

Luc De CoomanGuido AertsFilip Van OpstaeleKoen GoirisEvelien SyrynGert De RouckMarjan De RidderDenis De Keukeleire

A2 Journal Article in CEREVISIA

New trends in advanced hopping, part 2 : application of varietal hop aromas

Luc De CoomanGuido AertsFilip Van OpstaeleKoen GoirisEvelien SyrynGert De RouckMarjan De RidderDenis De Keukeleire

A2 Journal Article in CEREVISIA

Photooxidative degradation of beer bittering principles: product analysis with respect to lightstruck flavour formation

Kevin HuvaereBart SinnaeveJan Van BocxlaerDenis De Keukeleire

A1 Journal Article in PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Riboflavin-sensitized photooxidation of isohumulones and derivatives

Kevin HuvaereK OLSENML ANDERSENLH SKIBSTEDArne HeyerickDenis De Keukeleire

A1 Journal Article in PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Studies on the mechanism of formation on the lightstruck flavor in beer

Kevin HuvaereDenis De Keukeleire

2003

2,5-bis-(2-hydroxybenzoylamino)pentanoic acid, a salicylic acid-metabolite isolated from chicken: Characterization and independent synthesis

Ulrik HillaertKris BaertJ ROZENSKISiska CroubelsDenis De KeukeleirePatrick De BackerSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase

Veerle VanheusdenHélène Munier-LehmannMatheus FroeyenLaurence DuguéArne HeyerickDenis De KeukeleireSylvie PochetRoger BussonPiet HerdewijnSerge Van Calenbergh

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Formation and accumulation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol during flowering of hops (Humulus lupulus L.)

Jelle De KeukeleireG OOMSArne HeyerickIsabel Roldán-RuizErik Van BockstaeleDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Photolysis of hop-derived trans-iso-alpha-acids and trans-tetrahydroiso-alpha-acids: product identification in relation to the lightstruck flavour of beer

Arne HeyerickYN ZHAOPatrick SandraKevin HuvaereFrederik RoelensDenis De Keukeleire

A1 Journal Article in PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Quantitation of soy-derived phytoestrogens in human breast tissue and biological fluids by high-performance liquid chromatography

J MAUBACHmarc brackeArne HeyerickHerman DepypereRudolphe SerreynMarcus MareelDenis De Keukeleire

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Radicaloid-type oxidative decomposition of beer bittering agents revealed

Kevin HuvaereML ANDERSENK OLSENLH SKIBSTEDArne HeyerickDenis De Keukeleire

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

2002

8-prenylnaringenin, the phytooestrogen in hops and beer, may influence the incidence of breast cancer.

Herman DepypereH RONGTom BoterbergR SERREYNChristophe StoveSABINE VAN SLAMBROUCKDenis De KeukeleireMarcus Mareelmarc bracke

Chemotaxonomic features associated with flavonoids of cannabinoid-free cannabis (Cannabis sativa subsp sativa L.) in relation to hops (Humulus lupulus L.).

Gerd VanhoenackerPhilippe Van RompaeyDenis De KeukeleirePatrick Sandra

A1 Journal Article in NATURAL PRODUCT LETTERS

Modulation of the phytoestrogenicity of beer by monoterpene alcohols present in various hop oil fractions

Arne HeyerickDenis De KeukeleireCarlos Van PeteghemSarah De Saeger

A1 Journal Article in JOURNAL OF THE INSTITUTE OF BREWING

Oestrogenic activity of the hop phyto-oestrogen, 8-prenylnaringenin.

S MILLIGANJ KALITAV POCOCKArne HeyerickL DE COOMANHaojing RongDenis De Keukeleire

A1 Journal Article in REPRODUCTION

Quantitation of soy phytoestrogens in human breast tissue and biological fluids.

J MAUBACHHerman DepypereRudolphe SerreynDenis De KeukeleireM MAREELMarcel Bracke

Synthesis of homoceramides, novel ceramide analogues, and their lack of effect on the growth of hippocampal neurons

Steven De JongheInge LamoteK VENKATARAMANSA BOLDINUlrik HillaertJ ROZENSKIC HENDRIXR BUSSONDenis De KeukeleireSerge Van Calenbergh et al.

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

The oxygenated sesquiterpenoid fraction of hops in relation to the spicy hop character of beer

K GoirisM De RidderG De RouckA BoeykensF Van OpstaeleG AertsL De CoomanDenis De Keukeleire

A1 Journal Article in JOURNAL OF THE INSTITUTE OF BREWING

2001

8-Prenylnaringenin, the phytoestrogen in hops and beer, upregulates the function of the E-cadherin/catenin complex in human mammary carcinoma cells

Haojing RongTom BoterbergJulie MaubachChristophe StoveHerman DepypereSéverine Van SlambrouckRudolphe SerreynDenis De KeukeleireMarcus MareelMarc Bracke

A1 Journal Article in EUROPEAN JOURNAL OF CELL BIOLOGY

Capillary zone electrophoresis for the analysis of phthalate-derivatized hydroxyl- and amino-containing compounds.

Gerd VanhoenackerDenis De KeukeleirePatrick Sandra

A1 Journal Article in JOURNAL OF SEPARATION SCIENCE

Comparative study of the stability of iso-a-acids, dihydroiso- a-acids and tetrahydroiso- a -acids during beer ageing

L DE COOMANG AERTSA WITTERSM DE RIDDERA BOEYKENSK GOIRISDenis De Keukeleire

Comparative study of the stability of iso-a-acids, dihydroiso- a-acids and tetrahydroiso- a -acids during beer ageing.

L DE COOMANG AERTSA WITTERSM DE RIDDERA BOEYKENSK GOIRISDenis De Keukeleire

A2 Journal Article in Cerevisiae-Belgian Journal of Brewing and Biotechnology

Comparison of high-performance liquid chromatography - Mass spectroscopy and capillary electrophoresis - Mass spectroscopy for the analysis of phenolic compounds in diethyl ether extracts of red wines.

Gerd VanhoenackerAndré De VilliersKarel LazouDenis De KeukeleirePatrick Sandra

A1 Journal Article in CHROMATOGRAPHIA

Fyto-oestrogenen uit hop

Denis De Keukeleire

A4 Journal Article in FARMA-SFEER

Mechanism for the lightstruck flavor in beer revealed by time-resolved electron paramagnetic resonance.

CS BURNSArne HeyerickDenis De KeukeleireMDE FORBES

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

Prenylated hop flavonoids are key agents in relation to health-beneficial properties of beer

Denis De KeukeleireSR MILLIGANJC KALITAV POCOCKL DE COOMANArne HeyerickHaojing Rong

Single-run capillary electrochromatographic analysis of hop acids and prenylated hop flavonoids.

Gerd VanhoenackerAnna DermauxDenis De KeukeleirePatrick Sandra

A1 Journal Article in JOURNAL OF SEPARATION SCIENCE

Unraveling the mechanism of the lightstruck flavor of beer

Arne HeyerickDenis De Keukeleire

2000

Alterations of the profiles of iso-alpha-acids during beer ageing, marked instability of trans-iso-alpha-acids and implications for beer bitterness consistency in relation to tetrahydroiso-alpha-acids.

L DE COOMANG AERTSH OVERMEIREDenis De Keukeleire

A1 Journal Article in JOURNAL OF THE INSTITUTE OF BREWING

Brazilian beers: Blond is beautiful, dark is dreadful. An expert's view.

Denis De Keukeleire

A1 Journal Article in QUIMICA NOVA

De chemische essentie van hop en bier

Denis De Keukeleire

A4 Journal Article in ESSAYS VOOR HET CHEMIE ONDERWIJS

Evaluatie van de kwaliteit en toepassingen in de brouwerij van geavanceerde hopproducten, gebaseerd op bitterstoffen en aroma's.

A BOEYKENSM DE RIDDERH OVERMEIREL DE COOMANG AERTSDenis De Keukeleire

A2 Journal Article in Cerevisiae-Belgian Journal of Brewing and Biotechnology

Functional properties of hop polyphenols

Denis De KeukeleireLuc De CoomanHJ RONGArne HeyerickJ KALITASR MILLIGAN

Fundamentals of beer and hop chemistry.

Denis De Keukeleire

A1 Journal Article in QUIMICA NOVA

Intramolecular ortho and meta photocycloadditions of 4-phenoxybut-1-enes substituted in the arene residue with carbomethoxy, carbomethoxymethyl, and 2-carbomethoxyethyl groups.

K VIZVARDIS TOPPETGJ HOORNAERTDenis De KeukeleireP BAKOE VAN DER EYCKEN

A1 Journal Article in JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

Quantitation of 8-prenylnaringenin, a novel phytoestrogen in hops (Humulus lupulus L.), hop products, and beers, by benchtop HPLC-MS using electrospray ionization.

Haojing RongYining ZhaoKarel LazouDenis De KeukeleireSR MILLIGANPatrick Sandra

A1 Journal Article in CHROMATOGRAPHIA

Quantitative HPLC analysis of acids in Brazilian cachacas and various spirits using fluorescence detection of their 9-anthrylmethyl esters.

RJ DO NASCIMENTONR CARDOSODenis De KeukeleireBD LIMA-NETODW FRANCO

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Simultaneous analysis of hop acids and prenylated flavanoids by microemulsion electrokinetic chromatography with diode array detection.

Gerd VanhoenackerHaojing RongDenis De KeukeleireWilly BaeyensG VAN DER WEKENP SANDRA

A2 Journal Article in BIOMEDICAL CHROMATOGRAPHY

Synthesis and biological evaluation of ceramide analogues with substituted aromatic rings or an allylic fluoride in the sphingoid moiety.

Ilse Van OvermeireSA BOLDINK VENKATARAMANR ZISLINGSteven De JongheSerge Van CalenberghDenis De KeukeleireAH FUTERMANPiet Herdewijn

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of fluorinated sphinganine and dihydroceramide analogues.

Steven De JongheIlse Van OvermeireSerge Van CalenberghC HENDRIXR BUSSONDenis De KeukeleirePiet Herdewijn

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The endocrine activities of 8-prenylnaringenin and related hop (Humulus lupulus L.) flavonoids.

SR MILLIGANJC KALITAV POCOCKV VAN DE KAUTERJF STEVENSML DEINZERHaojing RongDenis De Keukeleire

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM

1999

5 '-deoxy congeners of 9-(3-amido-3-deoxy-beta-D-xylofuranosyl)-N-6-cyclopentyladenine: New adenosine A(1) receptor antagonists

Serge Van CalenberghA LINKS FUJIKAWAVeerle VanheusdenDenis De KeukeleireA IJZERMANPiet Herdewijn

5 '-Deoxy congeners of 9-(3-amido-3-deoxy-beta-D-xylofuranosyl)-N-6-cyclopentyladenine: New adenosine A(1) receptor antagonists and inverse agonists

Serge Van CalenberghA LINKS FUJIKAWAVeerle VanheusdenDenis De KeukeleireAP IJZERMAN

Chemiluminescence-based liquid chromatographic determination of hydrochlorothiazide and captopril.

Jin OuyangWilly BaeyensJ DELANGHEG VAN DER WEKENW VAN DAELEDenis De KeukeleireAMG CAMPANA

A1 Journal Article in ANALYTICA CHIMICA ACTA

Determination of the hop-derived phytoestrogen, 8-prenylnaringenin, in beer by gas chromatography/mass spectrometry.

J TEKELDenis De KeukeleireHaojing RongEls DaeseleireCarlos Van Peteghem

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effect of aromatic short-chain analogues of ceramide on axonal growth in hippocampal neurons.

Ilse Van OvermeireSA BOLDINFilip DumontSerge Van CalenberghG SLEGERSDenis De KeukeleireAH FUTERMANPiet Herdewijn

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Hop als medicinale plant: sedatieve en oestrogene eigenschappen.

Denis De Keukeleire

A3 Journal Article in S.W.A.V., tijdschrift van de Socio-wetenschappelijke Apothekersvereniging

Identification of a potent phytoestrogen in hops (Humulus lupulus L.) and beer.

SR MILLIGANJC KALITAArne HeyerickHaojing RongL DE COOMANDenis De Keukeleire

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM

Lead optimization of N⁶-cyclopentyl-3'-amido-3'-deoxyxylofuranosyladenines as adenosine A₁ receptor antagonists

Serge Van CalenberghA LinkDenis De KeukeleirePiet Herdewijn

A1 Journal Article in NUCLEOSIDES & NUCLEOTIDES

Sedative and oestrogenic poperties of hops.

Denis De Keukeleire

A2 Journal Article in Revista Italiana EPPOS, Istituto Tetrahedron, Milano, Italy

Structure-activity relationship of short-chain sphingoid bases as inhibitors of sphingosine kinase.

Steven De JongheIlse Van OvermeireS POULTONC HENDRIXR BUSSONSerge Van CalenberghDenis De KeukeleireS SPIEGELPiet Herdewijn

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and apoptogenic activity of fluorinated ceramide and dihydroceramide analogues

Steven De JongheIlse Van OvermeireJ. GunstAndré De BruynC. HendrixSerge Van CalenberghR. BussonDenis De KeukeleireJan PhilippéPiet Herdewijn

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1998

Automated reporting on the quality of hops and hop products.

Denis De KeukeleireFrank DavidK HaghebaertPatrick Sandra

A1 Journal Article in JOURNAL OF THE INSTITUTE OF BREWING

Chemiluminescence-based detection: principles and analytical applications in flowing streams and in immunoassays.

Willy BaeyensSG SCHULMANAC CALOKERINOSY ZHAOAMG CAMPANAK NAKASHIMADenis De Keukeleire

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Flow-injection analysis of hydrochlorothiazide applying sensitised chemiluminescence detection : optimisation in view of narrow-bore HPLC

Jin OuyangWilly BaeyensJoris DelangheGita Van Der WekenDenis De KeukeleireAC Calokerinos

Geavanceerde hopproducten : evaluatie en toepassingsmogelijkheden in KMO brouwerijen

Luc De CoomanGuido AertsH. OvermeireGert De RouckS. SamaeyDenis De Keukeleire

A2 Journal Article in CEREVISIA

Identification of isoflavones in the roots of Pueraria lobata.

Haojing RongJF STEVENSML DEINZERLuc De CoomanDenis De Keukeleire

A1 Journal Article in PLANTA MEDICA

Narrow-bore HPLC analysis of isoflavonoid aglycones and their O- and C-glycosides from Pueraria lobata

Haojing RongDenis De KeukeleireLuc De CoomanWilly BaeyensGuido Van Der Weken

Narrow-bore liquid chromatography coupled to chemiluminescence detection for the analysis of pharmaceutical preparations containing hydrochlorothiazide and captopril

Jin OuyangWilly BaeyensJoris DelangheGuido Van Der WekenDenis De KeukeleireW Van DaeleAM García CampañaAC Calokerinos

Quantitative analysis of hop acids, essential oils and flavonoids as a clue to the identification of hop varieties.

Luc De CoomanE EVERAERTDenis De Keukeleire

A1 Journal Article in PHYTOCHEMICAL ANALYSIS

1997

Access to a new type of homo-C-nucleosides with a 'split' 8-deazapurine via a 1,3-dipolar cycloaddition reaction

Serge Van CalenberghAndré De BruynJan SchramlNorbert BlatonOswald PeetersDenis De KeukeleireRobert BussonPiet Herdewijn

A1 Journal Article in NUCLEOSIDES & NUCLEOTIDES

Access to sterically confined nucleoside analogues via intramolecular photocycloadditions of arene-alkene trichromophores

Wim SaeyensDenis De KeukeleirePiet HerdewijnAndré De Bruyn

A1 Journal Article in BIOMEDICAL CHROMATOGRAPHY

Chiral 2-aryl-2-methyl-2H-1-benzopyrans: Synthesis, characterization of enantiomers, and barriers to thermal racemization.

G HARIEA SAMATR GUGLIELMETTII VANPARYSWim SaeyensDenis De KeukeleireK LORENZA MANNSCHRECK

A1 Journal Article in HELVETICA CHIMICA ACTA

Fully selective intramolecular ortho photocycloaddition of 4-(4-methoxyphenoxy)-3-(N-3-benzoylthymin-1-yl)but-1-ene: An unprecedented benzene-thymine photocycloaddition.

Wim SaeyensR BUSSONJ VANDEREYCKENPiet HerdewijnDenis De Keukeleire

A1 Journal Article in CHEMICAL COMMUNICATIONS

Hop-derived phytoestrogens in beer?

Denis De KeukeleireLuc De CoomanArne HeyerickSR MILLIGAN

Licht en medicijnen

Denis De KeukeleireFrank Moerman

N6-Cyclopentyl-3'-substituted-xylofuranosyladenosines : a new class of non-xanthine adenosine A1 receptor antagonists

Serge Van CalenberghJacobien K von FrijtagDrabbe KünzelNorbert M BlatonOswald M PeetersJef RozenskiArhtur Van AerschotAndré De BruynDenis De KeukeleireAdriaan P IJzeman et al.

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Ortho photocycloaddition of substituted 4-phenoxybut-1-enes. Identification of rearranged photocycloadducts by NMR.

R BUSSONJ SCHRAMLWim SaeyensE VAN DER EYCKENPiet HerdewijnDenis De Keukeleire

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Photochromic behaviour of bis[4-(N,N-dimethylamino)phenyl]-substituted 3H-naphtho[2,1-b]pyran and 2H-1-benzopyran.

G HARIEA SAMATR GUGLIELMETTIDenis De KeukeleireWim SaeyensI VANPARYS

A1 Journal Article in TETRAHEDRON LETTERS

Qualitative and quantitative high-performance liquid chromatographic analysis of aldehydes in Brazilian sugar cane spirits and other distilled alcoholic beverages.

RF NASCIMENTOJC MARQUESBSL NETODenis De KeukeleireDW FRANCO

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

The oestrogen ic activity of hops (Humulus lupulus L.) revisited

Denis De KeukeleireSR MILLIGANLuc De CoomanArne Heyerick

A4 Journal Article in Pharm. Pharmacol. Lett., 7e jg

1996

Conference report on 8th Inter-American Photochemical Society Conference, Foz do Iguaçu, Brazil, 19-24 May 1996

Denis De Keukeleire

Conference report on VIIth International Symposium on Luminescence Spectrometry in Biomedical Analysis, Nice, France, 17-19 April 1996

Denis De Keukeleire

Convenient access to 4,4-disubstituted 4H-chromenes. Synthesis of 4-methyl-4-(4-methoxyphenyl)-benzo[h]-4H-chromene.

Denis De KeukeleireWim Saeyens

A1 Journal Article in SYNTHETIC COMMUNICATIONS

Fractionering van hop voor stabiliteit van de biersmaak en diversificatie van het bieraroma

Denis De Keukeleire

A2 Journal Article in CEREVISIA

Nieuwe hopbereidingen en sensorische aspecten van bier

Denis De Keukeleire

Role of isohumulones and reduced isohumulones in head retention

Denis De Keukeleire

VIIth International symposium on luminescence spectrometry in biomedical analysis : detection techniques and applications in chromatography and capillary electrophoresis : foreword

Willy BaeyensDenis De Keukeleire

Editorial material

1995

A novel approach to differentiate hop varieties using principal component analysis of quantitative bitter acids data

Denis De KeukeleireLuc De CoomanE EVERAERT

Evaluation of 2-iminoimidazolidin-4-one and thymine as respective internal standards for normal-phase and reversed-phase high-performance liquid chromatographic determination of creatinine in human serum

Linda ThienpontKG VANLANDUYTDietmar StöcklWim SaeyensDenis De KeukeleireAndreas De Leenheer

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS

Intramolecular ortho and meta photocycloadditions of 3-alkyl-4-phenoxybut-1-enes

E. VandereyckenDenis De KeukeleireAndré De Bruyn

A1 Journal Article in TETRAHEDRON LETTERS

Photochemistry in Belgium - University of Ghent

Denis De Keukeleire

Photoreactivity of arene-alkene bichromophores containing an aryloxy moiety

Chuan-Yue WangDenis De Keukeleire

Stereochemical features of meta photocycloadducts derived from 3-alkyl-4-phenoxybut-1-enes

Erik Van der EyckenDenis De KeukeleireAndré De BruynJohan Van der EyckenA Gilbert

A1 Journal Article in RECUEIL DES TRAVAUX CHIMIQUES DES PAYS-BAS-JOURNAL OF THE ROYAL NETHERLANDS CHEMICAL SOCIETY

Structural assignment of the intramolecular meta photocycloadduct isomers from 4-phenoxybut-1-enes and 3-benzyloxyprop-1-enes by proton NMR spectroscopy

DC BlakemoreA GilbertAndré De BruynDenis De KeukeleireErik Van der Eycken

A1 Journal Article in MAGNETIC RESONANCE IN CHEMISTRY

1994

Fotochromie en de potentiële industriële toepassingen

I Van ParysDenis De Keukeleire

Intramolecular photocycloaddition reactions of 4-phenoxy-but-l-enes.

Denis De KeukeleireSL HED BLAKEMOREA GILBERT

A1 Journal Article in JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

Quantitative luminescence spectrometry in biomedical analysis

Denis De KeukeleireWilly Baeyens

Separation and quantification of all main hop acids in different hop cultivars by microesmulsion electrokinetic chromatography.

R SZUCSJohan VindevogelE EVERAERTL DECOOMANPatrick SandraDenis De Keukeleire

A1 Journal Article in JOURNAL OF THE INSTITUTE OF BREWING

1993

Chemical and biochemical aspects of neurolathyrism

Jehangir K KhanF. LambeinDenis De Keukeleire

Phenolic markers in chemotaxonomy and plant cultivar recognition

CF VAN SUMERELuc De CoomanE EVERAERTDenis De KeukeleireK VANDE CASTEELE

Phenolic Markers in Chemotaxonomy and Plant cultivar recognition.

CF VAN SUMERELuc De CoomanEls EveraertDenis De KeukeleireK VANDE CASTEELE

Bookchapter in Polyphenolic Phenomena

Photochemical strategies for the construction of polycyclic molecules.

Denis De KeukeleireSL HE

A1 Journal Article in CHEMICAL REVIEWS

SOLVATOCHROMIC AND PHOTOCHROMIC CHARACTERISTICS OF NEW 1,3-DIHYDROSPIRO[2H-INDOLE-2,2'-[2H]-BIPYRIDO[3,2-F][2,3-H][1,4]BENZOXAZINES].

JL POZZOA SAMATR GUGLIELMETTIDenis De Keukeleire

A1 Journal Article in JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2

1992

NMR study of complex triquinanes and bulleranes derived from photoisomerization of aryl-substituted norbornan-2-ones

Denis De KeukeleireSL HeAndré De Bruyn

A1 Journal Article in MAGNETIC RESONANCE IN CHEMISTRY

Photoinduced formation of the dimethyl acetals of norboman-2-one derivatives containing a cyclic ether function in alpha-position.

Denis De KeukeleireY RUYSSCHAERT

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Tandem Norrish Type I reaction and intramolecular arene-alkene meta-photocycloaddition: novel photoisomerization of aryl-substituted norbornan-2-ones to triquinanes.

Denis De KeukeleireSL HE

A1 Journal Article in JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS

The history and analytical chemistry of beer bitter acids

Denis De KeukeleireJohan VindevogelR SzucsPatrick Sandra

A1 Journal Article in TRAC-TRENDS IN ANALYTICAL CHEMISTRY

1991

Charge-asymmetry and charge-alternation concepts in inorganic and organic molecules.

Guido Van HooydonkDenis De Keukeleire

A1 Journal Article in THEOCHEM-JOURNAL OF MOLECULAR STRUCTURE

Charge-asymmetry and charge-alternation concepts in inorganic and organic molecules. Short Communication

Guido Van HooydonkDenis De Keukeleire

A2 Journal Article in Journal of Molecular Structure (Theochem), vol. 251

Chemistry and analysis of hop and beer bitter acids

Maurice VerzeleDenis De Keukeleire

Fluorescence Spectroscopy: An introduction

F DE SCHRYVERDenis De Keukeleire

Bookchapter in Luminescence techniques in chemical and biochemical analysis. Marcel Dekker, Inc., New York

Synthesis and spectrokinetic properties of photochromic spiropyrans. Review.

A SAMATDenis De KeukeleireR GUGLIELMETTI

A2 Journal Article in Bull. Soc. Chim. Belg.

1990

Regioselective and stereoselective control in the alkylation of 1-alkoxy-1,4-cyclohexadienes by the chiral auxiliary approach : enantioselective synthesis of precursors for cis-hydrindanes

Dirk StanssensDenis De KeukeleireMaurits Vandewalle

A1 Journal Article in TETRAHEDRON-ASYMMETRY

1987

A new and facile perhydroazulene formation : the total synthesis of the carotane (+)-daucene

Frans AudenaertDenis De KeukeleireMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

Chelation controlled regioselective alkylation and 1,4 chirality transfer in optically active 1-alkoxy-1,4-cyclohexadienes

D StanssensDenis De KeukeleireMaurits Vandewalle

A1 Journal Article in TETRAHEDRON LETTERS

Chemoselective intramolecular nitrone-olefin cycloaddition : an efficient route to functionalized cis hydrindane systems

Dirk STANSSENSDenis De KeukeleireMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1985

Photoaddition with 1,2-bis(trimethylsiloxy)cyclobutene : a versatile entry to the stereocontrolled total synthesis of various sesquiterpenes and diterpenes

Denis De KeukeleireMartine Van AudenhoveLuc Van HijfteFrans AudenaertMaurits Vandewalle

A1 Journal Article in JOURNAL OF PHOTOCHEMISTRY

The synthetic recogition of photochemical α-cleavage in 2-norbornanones

Denis De KeukeleireLuc QuaghebeurYves RuysschaertPol StormeEric Van der EyckenMaurits Vandewalle

1984

Bicyclic isomerization products of humulone

M van De VeldeDenis De KeukeleireAndré De BruynMaurice Verzele

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Photoaddition with 1,2-bis(trimethylsiloxy)cyclobutene : a versatile entry to the stereocontrolled total synthesis of various sesqui- and diterpenes

Denis De KeukeleireMartine Van AudenhoveLuc Van HijfteFrans AudenaertMaurits Vandewalle

Study of a model system for asymmetric induction in [2C + 2C] photoannelation reactions

Kathleen BruneelDenis De KeukeleireMaurits Vandewalle

A1 Journal Article in JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1

Unusual course of a type II photoreaction

G BlondeelAndré De BruynDenis De Keukeleire

A1 Journal Article in TETRAHEDRON LETTERS

1983

Regioselectivity in the chemical and enzymatic reactions between gluthatione and phenylglycidyl ether

Elfrida Van Den EeckhoutJE SinsheimerWilly BaeyensDenis De KeukeleireAndré De BruynP De Moerloose

A1 Journal Article in ANALYTICAL LETTERS PART A-CHEMICAL ANALYSIS

Regioselectivity in the glutathione-phenylglycidyl ether reaction : 1H NMR characterization of the adduct

André De BruynDenis De KeukeleireElfrida Van Den EeckhoutWilly Baeyens

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1982

Chiral induction in [2C + 2C] photoannelations

Denis De KeukeleireKathleen BruneelMaurits Vandewalle

1981

A short and stereoselective entry into the 2-substituted eudesmane series

Martine Van AudenhoveDenis De KeukeleireMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

The anti-iso-alpha-acids : concept and review of current research

Leo De TaeyeDenis De KeukeleireMaurice Verzele

A2 Journal Article in JOURNAL OF THE AMERICAN SOCIETY OF BREWING CHEMISTS

1980

A (π2+π2) photocycloaddition reaction as a facile route to angularly substituted cis-hydrindanes and cis-decalanes

Martine Van AudenhoveDenis De KeukeleireMaurits Vandewalle

A1 Journal Article in TETRAHEDRON LETTERS

Mass spectrometry used to discriminate between cis-syn-cis and cis-anti-cis photoadducts

Martine Van AudenhoveDenis De KeukeleireMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

The total synthesis of (-)dihydrodictyopterone : a photochemical synthetic approach to sesquiterpenes

Denis De KeukeleireMartine Van AudenhoveMaurits Vandewalle

1979

6,6-Dimethoxy bicyclo[3.2.0]heptan-2-one : an intermediate for prostanoid synthons

Denis De KeukeleireHugo De WildeFrank VerzeleWilfried WyffelsMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Bicyclo[3,2,0]heptan-2-ones : a photochemical route to prostanoid synthons

Maurits VandewalleMagda ClaeysDenis De KeukeleireHugo De WildeRoeland MijngheerDaniël TermontMartine Van AudenhoveFrank VerzeleWilfried Wyffels

Dual pathways in the 'reversed' isomerisation of humulone

Leo De TaeyeDenis De KeukeleireMaurice Verzele

A1 Journal Article in CHEMISTRY & INDUSTRY

Isolation and identification of the anti-isohumulones and the anti-acetylhumulinic acids

Leo De TaeyeDenis De KeukeleireMaurice Verzele

A1 Journal Article in TETRAHEDRON

New members of the hop anti iso-α-acids series

Leo De TaeyeDenis De KeukeleireMaurice Verzele

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1978

On the structure of tricyclodehydroisohumulone

L De TaeyeDenis De KeukeleireAndré De BruynMaurice Verzele

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Regioselectivity in [π2 + π2] photocycloaddition reactions between cyclopent-2-enones and β-oxysubstituted acrylates

Martine Van AudenhoveDaniël TermontDenis De KeukeleireMaurits VandewalleMagda Claeys

A1 Journal Article in TETRAHEDRON LETTERS

Transformation of cyclopent-2-enones into guaianolides, pseudoguaianolides and prostaglandins via (π2 + π2) photocycloaddition reactions

Denis De KeukeleireDaniël TermontMartine Van AudenhoveMaurits Vandewalle

Tricyclo-oxy and tricyclo-peroxycolupulones

Marc De PotterDenis De KeukeleireAndré De BruynMaurice Verzele

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1977

Anti-isohumulone and its derivatives

L De TaeyeDenis De KeukeleireMaurice Verzele

A1 Journal Article in TETRAHEDRON

Differentiation between regio- and stereoisomers of bicyclo[3,2,0]heptanone-2 derivatives by chemical ionization mass spectrometry

D TermontF Van GaeverDenis De KeukeleireM ClaeysMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

New derivatives of the alloisohumulones

Leo De TaeyeDenis De KeukeleireMaurice Verzele

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Photoisomerization in α,β-unsaturated carboxylic acids

Jean-Marie BiotDenis De KeukeleireMaurice Verzele

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Recent developments in hop chemistry

Leo De TaeyeDenis De KeukeleireE. SiaensMaurice Verzele

Regio- and stereo-selectivity in [π2 +π2] photocycloaddition reactions between cyclopent-2-enone and electron-rich alkenes

Daniël TermontDenis De KeukeleireMaurits Vandewalle

A1 Journal Article in JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1

The metal ion catalysed oxidation of hexahydrocolupulone

E SiaensDenis De KeukeleireMaurice Verzele

A1 Journal Article in TETRAHEDRON

1976

2-acyl-4-alk(en)yltetronic acid, a new oxidation product of hop α-acids

Denis De KeukeleireL De TaeyeMaurice Verzele

A1 Journal Article in TETRAHEDRON

On the stability of 4-hydroxyhexahydrocolupulone

E SiaensDenis De KeukeleireMaurice Verzele

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Regio- and stereoselectivity in (2π + 2π) photocycloaddition reactions between 2-cyclopentenone and heteroatom-substituted alkenes

Daniël TermontDenis De KeukeleireMaurits Vandewalle

Regiospecific singlet oxygen oxidation of (-)R-tetrahydrohumulone and hexahydrocolupulone

Denis De KeukeleireE SiaensMaurice Verzele

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1974

The chemical constituents of hops and their contribution to beer

Denis De KeukeleireMaurice Verzele

Bookchapter in Industrial aspects of biochemistry

1972

The absolute configuration of iso-α-acids and derived substances and the implications for α-acids isomerization

Denis De KeukeleireMaurice Verzele

A1 Journal Article in JOURNAL OF THE INSTITUTE OF BREWING

1971

Humulinic acids : X. The hydrogenolysis of humulinic acids

Denis De KeukeleireMaurice Verzele

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

On the hydroxyl group : PMR signals in 2- and 4-acrylresorcinols and the structure of humulone

Denis De KeukeleireR. VanheertumMaurice Verzele

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

The absolute configuration of the isohumulones and humulinic acids

Denis De KeukeleireMaurice Verzele

A1 Journal Article in TETRAHEDRON

1970

The stereochemistry of (-)humulone

Denis De KeukeleireMaurice Verzele

A1 Journal Article in JOURNAL OF THE INSTITUTE OF BREWING

The structure and the absolute configuration of (-)humulone

Denis De KeukeleireMaurice Verzele

A1 Journal Article in TETRAHEDRON

Foreword: Vllth International Symposium on Liminescence Spectrometry in Biomédical Analysis. Detection Techniques and Applications in Chromatography and Capillary Electrophoresis.

Willy BaeyensDenis De Keukeleire

Hops and hop products, Hans Carl, Nürnberg, Duitsland, 1997, pp. 185 ISBN 3-418-00756-2.

JR BENITEZA FORSTERDenis De KeukeleireM MOIRF SCHARPELC VERHAGENKT WESTWOOD

Intramolecular photocycloaddition reactions of 4-phenoxybut-l-enes. J. Photochem. Photobiol. Section A: Chemistry, (1993).

Denis De KeukeleireSL HED BLAKEMOREA GILBERT

A2 Journal Article

NMR studies on complex triquinanes derived from intramolecular arene-alkene meta photocycloaddition reactions. Magn. Reson. Chem., vol. 30, pp. S7-S14 (1992).

Denis De KeukeleireSL HEA DE BRUYN

Novel methodology for unambiguous identification of hop varieties'. Proceedings of the 23rd Convention Australia and New Zealand Section, Institute of Brewing, Sydney, Australia, April 10-15th, 1994, Winetitles -Hyde Park Press, Adelaide, Australia, 1994, pp. 129-132.

Denis De KeukeleireLuc De CoomanE EVERAERTP SANDRAJ VINDEVOGELR SZUCS

Photochemistry of beer. The Spectrum, 1991, 4, 1-7.

Denis De Keukeleire

Phytochemical investigation of Alocasia odora and Euphorbia ebracteolata. Pharmacy World & Science, Suppl. H., vol. 15, p. H7 (1993).

Denis De KeukeleireX WANG

Stereoselective construction of unusual polycyclic systems via intramo lecular meta-photocycloaddition of (but-3-enyl)phenyl ethers. '14th IUPAC' Symposium on Photochemistry, K.U.Leuven, 19-25 July 1992, Abstract, Belgium, 1992.

Denis De KeukeleireHE SHU-LIN

Synthesis of exo-2-(2-hydroxyethyl)biclyclo[3.2.1]oct-6-en-8-one' Photo chemical key steps in organic synthesis, J. Mattay, A.G. Griesbeck, Eds., VCH. Weinheim, Germany, 1994, pp. 178-180.

Denis De Keukeleire

Tandem Norrish Type I reaction and intramolecular arene-alkene meta photocycloaddition: novel photoisomerization of aryl-substituted 2-norborna-nones to triquinanes. J. Chem. Soc, Chem. Commun., pp. 419-420 (1992).

Denis De KeukeleireSL HE

A2 Journal Article

The effects of hops on flavour stability and beer properties. Cerevisia and Biotechnology, vol. 18, nr. 4, pp. 33-46 (1993).

Denis De Keukeleire

The lightstruck flavour of beer. European Photochemistry Assoc' ition Newsletter, N° 49, pp. 28-36 (1993).

Denis De Keukeleire

The synthetic potential of the intramolecular meta photocycloaddition in arenealkene bichromophoric systems containing oxygen in the tether. Aldrichim. Acta, 1994, 27, pp. 59-69.

Denis De Keukeleire