Research Explorer

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Researcher

Delfien Staelens

Publications & Research Data

Awards & Distinctions

10 Results

2025

Aberrant strand transfer events across multiple stages of reverse transcription shape the heterogeneous landscape of the HIV-1 reservoir

Jarryt HardyVirginie MortierYiannis De MeersmanDelfien StaelensEls DemecheleerMarlies SchauvliegeCiel VermeerschElizaveta PadalkoChris Verhofstede

A1 Journal Article in COMMUNICATIONS BIOLOGY

2024

Reverse transcription of plasma-derived HIV-1 RNA generates multiple artifacts through tRNA(Lys-3)-priming

Jarryt HardyEls DemecheleerMarlies SchauvliegeDelfien StaelensVirginie MortierChris Verhofstede

A1 Journal Article in MICROBIOLOGY SPECTRUM

2020

High frequency of new recombinant forms in HIV-1 transmission networks demonstrated by full genome sequencing

Laura HebberechtVirginie MortierKenny DauweMarlies SchauvliegeDelfien StaelensEls DemecheleerKarolien StoffelsFien VanroyeMarie-Luce DelforgeEllen Vancutsem et al.

A1 Journal Article in INFECTION GENETICS AND EVOLUTION

2019

Single genome sequencing of near full-length HIV-1 RNA using a limiting dilution approach

Laura HebberechtLeen VancoillieMarlies SchauvliegeDelfien StaelensEls DemecheleerJarryt HardyVirginie MortierChris Verhofstede

A1 Journal Article in JOURNAL OF VIROLOGICAL METHODS

2018

Frequency of occurrence of HIV-1 dual infection in a Belgian MSM population

Laura HebberechtLeen VancoillieMarlies SchauvliegeDelfien StaelensKenny DauweVirginie MortierChris Verhofstede

A1 Journal Article in PLOS ONE

Meticulous plasma isolation is essential to avoid false low-level viraemia in Roche Cobas HIV-1 viral load assays

Virginie MortierLeen VancoillieKenny DauweDelfien StaelensEls DemecheleerMarlies SchauvliegeSylvie DinakisTom Van MaerkenGéraldine DessillyJean Ruelle et al.

A1 Journal Article in ANTIVIRAL THERAPY

Quantification of total HIV-1 DNA in buffy coat cells, feasibility and potential added value for clinical follow-up of HIV-1 infected patients on ART

Virginie MortierEls DemecheleerDelfien StaelensMarlies SchauvliegeKenny DauweSylvie DinakisLaura HebberechtLeen VancoillieChris Verhofstede

A1 Journal Article in JOURNAL OF CLINICAL VIROLOGY

2016

Deep sequencing of HIV-1 RNA and DNA in newly diagnosed patients with baseline drug resistance showed no indications for hidden resistance and is biased by strong interference of hypermutation

Kenny DauweDelfien StaelensLeen VancoillieVirginie MortierChris Verhofstede

A1 Journal Article in JOURNAL OF CLINICAL MICROBIOLOGY

2013

Frequency and predictors of HIV-1 co-receptor switch in treatment naive patients

Virginie MortierKenny DauweLeen VancoillieDelfien StaelensFilip Van WanzeeleDirk VogelaersLinos VandekerckhoveKristen ChalmetChris Verhofstede

A1 Journal Article in PLOS ONE

2010

Epidemiological study of phylogenetic transmission clusters in a local HIV-1 epidemic reveals distinct differences between subtype B and non-B infections

Kristen ChalmetDelfien StaelensStijn BlotSylvie DinakisJolanda PelgromJean PlumDirk VogelaersLinos VandekerckhoveChris Verhofstede

A1 Journal Article in BMC INFECTIOUS DISEASES