Research Explorer

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Researcher

Dariusz Ratman

Awards & Distinctions

18 Results

2019

Mechanisms underlying the functional cooperation between PPARα and GRα to attenuate inflammatory responses

Nadia BougarneViacheslav MylkaDariusz RatmanIlse BeckJonathan ThommisLode De CauwerJan TavernierBart StaelsClaude LibertKarolien De Bosscher

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2018

The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages

Viacheslav MylkaJulie DeckersDariusz RatmanLode De CauwerJonathan ThommisRiet De RyckeFrancis ImpensClaude LibertJan TavernierWim Vanden Berghe et al.

A1 Journal Article in AUTOPHAGY

2017

Compound A influences gene regulation of the dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment

Sofie DesmetNadia BougarneLaura Van MoortelLode De CauwerJonathan ThommisM VuylstekeDariusz RatmanR HoutmanJan TavernierKarolien De Bosscher

A1 Journal Article in SCIENTIFIC REPORTS

Coregulator profiling of the glucocorticoid receptor in lymphoid malignancies

Dorien ClarisseJonathan ThommisKarlien Van WesemaelRene HoutmanDariusz RatmanJan TavernierFritz OffnerIlse BeckKarolien De Bosscher

A1 Journal Article in ONCOTARGET

Interleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia

Oonagh PaerewijckBrecht MaertensLeentje DreesenFrederik Van MeulderIris PeelaersDariusz RatmanRobert W LiErik LubbertsKarolien De BosscherPeter Geldhof

A1 Journal Article in SCIENTIFIC REPORTS

Semi-synthetic sapogenin exerts neuroprotective effects by skewing the brain ischemia reperfusion transcriptome towards inflammatory resolution

Laura García-PupoJeney Ramírez SánchezDariusz RatmanClaudina Perez NovoKen DeclerckKarolien De BosscherMarios Nektarios MarkakisGerrit BeemsterArmando ZaldoYanier Nuñez Figueredo et al.

A1 Journal Article in BRAIN BEHAVIOR AND IMMUNITY

2016

Activation of the glucocorticoid receptor in acute inflammation : the SEDIGRAM concept

Karolien De BosscherIlse BeckDariusz RatmanWim Vanden BergheClaude Libert

A1 Journal Article in TRENDS IN PHARMACOLOGICAL SCIENCES

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα

Dariusz RatmanViacheslav MylkaNadia BougarneMichal PawlakSandrine CaronNathalie HennuyerRéjane PaumelleLode De CauwerJonathan ThommisMark H Rider et al.

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Unraveling the role of IL-17A in the intestinal immune response against the protozoan parasite Giardia muris by an RNA sequencing approach

Oonagh PaerewijckLeentje DreesenFrederik Van MeulderDariusz RatmanKarolien De BosscherRW LiPeter Geldhof

2015

Analysis of the protective immune response following intramuscular vaccination of calves against the intestinal parasite Cooperia oncophora

Frederik Van MeulderDariusz RatmanStefanie Van CoppernolleJimmy BorlooRW LiKoen ChiersWim Van Den BroeckKarolien De BosscherEdwin ClaereboutPeter Geldhof

A1 Journal Article in INTERNATIONAL JOURNAL FOR PARASITOLOGY

The transcriptional co-regulation of hepatic lipid metabolism by GR and PPARα

Dariusz RatmanKarolien De BosscherJan Tavernier

Unraveling the role of IL-17A in the intestinal immune response against the protozoan parasite Giardia muris by an RNA sequencing approach

Oonagh PaerewijckLeentje DreesenFrederik Van MeulderDariusz RatmanKarolien De BosscherRW LiPeter Geldhof

2014

Determining the coregulator profile of the endogenous glucocorticoid receptor in lymphoid malignancies using MARCoNI

Dorien ClarisseDariusz RatmanSofie DesmetJonathan ThommisRené HoutmanKarolien De BosscherIlse Beck

Hypoxia-inducible lipid droplet-associated (HILPDA) Is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion

Frits MattijssenAnastasia GeorgiadiTresty AndasarieEwa SzalowskaAnnika ZotaAnja Krones-HerzigChristoph HeierDariusz RatmanKarolien De BosscherLing Qi et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological levels of withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells

Katarzyna Szarc vel SzicKen Op De BeeckDariusz RatmanAn WoutersIlse BeckKen DeclerckKaren HeyninckErik FransenMarc BrackeKarolien De Bosscher et al.

A1 Journal Article in PLOS ONE

Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1

Karolien De BosscherIlse BeckLien DejagerNadia BougarneAnthoula GaigneauxSebastien ChateauvieuxDariusz RatmanMarc BrackeJan TavernierWim Vanden Berghe et al.

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

The increasing complexity of glucocorticoid receptor signaling and regulation

Sofie DesmetIlse BeckNadia BougarneDorien ClarisseJulie DeckersDariusz RatmanJan TavernierKarolien De Bosscher

A2 Journal Article in PROCEEDINGS OF THE BELGIAN ROYAL ACADEMIES OF MEDICINE

2013

How glucocorticoid receptors modulate the activity of other transcription factors: a scope beyond tethering

Dariusz RatmanWim Vanden BergheLien DejagerClaude LibertJan TavernierIlse BeckKarolien De Bosscher

A1 Journal Article in MOLECULAR AND CELLULAR ENDOCRINOLOGY