Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Researcher

Dario Priem

Publications & Research Data

Awards & Distinctions

19 Results

2025

ATG9A-mediated autophagy prevents inflammatory skin disease by limiting TNFR1-driven STING activation and ZBP1-dependent cell death

Dario PriemJon HuygheBarbara GilbertSimon VerdonckTom DelangheBruno VerstraetenEsther HostePeter VandenabeeleJonathan MaelfaitGeert van Loo et al.

A1 Journal Article in IMMUNITY

TAB2 controls a TAK1-independent cell death checkpoint at the level of TNFR1 complex II in the TNF pathway

Tom DelangheMike VadiAnnelore HaemsLisa WijnsInge BruggemanJon HuygheDario PriemPeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2023

Cell death checkpoints in the TNF pathway

Jon HuygheDario PriemMathieu Bertrand

A1 Journal Article in TRENDS IN IMMUNOLOGY

Detoxification mechanisms in the TNF pathway

Jon HuygheMathieu BertrandDario Priem

LC3-independent autophagy is vital to prevent TNF cytotoxicity

Dario PriemJon HuygheMathieu Bertrand

A1 Journal Article in AUTOPHAGY

NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis

Yves DondelingerDario PriemJon HuygheTom DelanghePeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH & DISEASE

Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice

Karel Van DammePieter HertensArne MartensElisabeth GilisDario PriemInge BruggemanAmelie FossoulJozefien DeclercqHelena Catharine AegerterAndy Wullaert et al.

A1 Journal Article in SCIENTIFIC REPORTS

2022

A20 controls RANK-dependent osteoclast formation and bone physiology

Arne MartensPieter HertensDario PriemVagelis RinotasTheodore MeletakosMeropi GennadiLisette Van HoveEls LouagieJulie CoudenysAmélie De Muynck et al.

A1 Journal Article in EMBO REPORTS

ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway.

Jon HuygheDario PriemLisette Van HoveBarbara GilbertJ FritschY UchiyamaEsther HosteGeert van LooMathieu Bertrand

A1 Journal Article in SCIENCE

2021

Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor

Tom DelangheJon HuygheSeungheon LeeDario PriemSamya Van CoillieBarbara GilbertSze Men ChoiPeter VandenabeeleAlexei DegterevGregory D. Cuny et al.

A1 Journal Article in CELL DEATH & DISEASE

2020

A20 and cell death-driven inflammation

Dario PriemGeert van LooMathieu Bertrand

A1 Journal Article in TRENDS IN IMMUNOLOGY

OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis

Lien VerboomArne MartensDario PriemEsther HosteMozes SzeHanna-Kaisa VikkulaLisette Van HoveSofie VoetJana RoelsJonathan Maelfait et al.

A1 Journal Article in CELL REPORTS

The ubiquitin-dependent regulation of the inflammatory response by A20 and MAGED1

Dario PriemMathieu Bertrand

Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities

Arne MartensDario PriemEsther HosteJessica VettersSofie RennenLeen CatrysseSofie VoetLaura DeelenMozes SzeHanna-Kaisa Vikkula et al.

A1 Journal Article in NATURE IMMUNOLOGY

2019

A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

Dario PriemMichael DevosSarah DruwéArne MartensKarolina SlowickaAdrian T TingManolis PasparakisWim DeclercqPeter VandenabeeleGeert van Loo et al.

A1 Journal Article in CELL DEATH & DISEASE

Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation

Yves DondelingerTom DelangheDario PriemMeghan A Wynosky-DolfiDaniel SorobeteaDiego Rojas RiveraPiero GiansantiRia RoelandtJulia GropengiesserKlaus Ruckdeschel et al.

A1 Journal Article in NATURE COMMUNICATIONS

2018

Monitoring RIPK1 phosphorylation in the TNFR1 signaling complex

Dario PriemYves DondelingerMathieu Bertrand

Bookchapter in Programmed necrosis : methods and protocols

2017

MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death

Yves DondelingerTom DelangheDiego Rojas RiveraDario PriemTinneke DelvaeyeInge BruggemanFranky Van HerreweghePeter VandenabeeleMathieu Bertrand

A1 Journal Article in NATURE CELL BIOLOGY

2016

Polyhydramnios, transient antenatal Bartter's syndrome, and MAGED2 mutations

Kamel LaghmaniBodo B BeckSung-Sen YangElie SeaayfanAndrea WenzelBjörn ReuschHelga VitzthumDario PriemSylvie DemaretzKlasien Bergmann et al.

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE