Research Explorer

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Researcher

Claus Bachert

970 Results

2023

Differential protease content of mast cells and the processing of IL-33 in Alternaria alternata induced allergic airway inflammation in mice

Olga KryskoDarya KorsakovaAndrea Renate TeufelbergerAmse De MeyerJill SteelsNatalie De RuyckJudith van OvostSharon Van NevelGabriële HoltappelsFrauke Coppieters et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Effects of biologics treatment in type 2-high chronic rhinosinusitis with nasal polyp patients

Sharon Van NevelTim MeeseGabriële HoltappelsNatalie De RuyckStijn VanheeNan ZhangFilip Van NieuwerburghClaus Bachert

Endotypes of chronic rhinosinusitis based on inflammatory and remodeling factors

Xiangdong WangYutong SimaYan ZhaoNan ZhangMing ZhengKun DuMin WangYue WangYun HaoYing Li et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

2022

A diagnostic model for predicting type 2 nasal polyps using biomarkers in nasal secretion

Zaichuan WangQiqi WangSu DuanYuling ZhangLimin ZhaoShujian ZhangLiusiqi HaoYan LiXiangdong WangChenshuo Wang et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

AROMA : real-world global registry of dupilumab for chronic rhinosinusitis with nasal polyps

Shahid SiddiquiClaus BachertAdam M. ChakerJoseph K. HanPeter HellingsAnju T. PetersEnrico HefflerSiddhesh KamatHaixin ZhangScott Nash et al.

A1 Journal Article in ERJ OPEN RESEARCH

Advances in chronic rhinosinusitis in 2020 and 2021

Zhaofeng XuYanran HuangTim DelemarreCarlo CavaliereNan ZhangClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Association between outdoor air pollution and chronic rhinosinusitis patient reported outcomes

S. PeetersC. WangE. M. BijnensD. M. A. BullensW. J. FokkensClaus BachertPeter HellingsT. S. NawrotS. F. Seys

A1 Journal Article in ENVIRONMENTAL HEALTH

Chemokine expression-based endotype clustering of chronic rhinosinusitis

Ulrike Förster-RuhrmannAgnieszka J. SzczepekGreta PierchallaJoachim W. FluhrMetin ArtucTorsten ZuberbierClaus BachertHeidi Olze

A1 Journal Article in JOURNAL OF PERSONALIZED MEDICINE

Chronic rhinosinusitis : natural history, impact on health-related quality of life, and patient perspectives

Asif Hameed KhanClaus BachertThibaut Van Zele

DC vaccines loaded with glioma cells killed by photodynamic therapy induce Th17 anti-tumor immunity and provide a four-gene signature for glioma prognosis

Maria VedunovaVictoria TurubanovaOlga VershininaMariia SaviukIuliia EfimovaTatiana MishchenkoRobrecht RaedtAnne VralChristian VanhoveDaria Korsakova et al.

A1 Journal Article in CELL DEATH & DISEASE

Differentiating neutrophilic and eosinophilic inflammation in chronic rhinosinusitis

Tim DelemarreClaus BachertElien Gevaert

Dupilumab efficacy and biomarkers in chronic rhinosinusitis with nasal polyps : association between dupilumab treatment effect on nasal polyp score and biomarkers of type 2 inflammation in patients with chronic rhinosinusitis with nasal polyps in the phase 3 SINUS‐24 and SINUS‐52 trials

Claus BachertJonathan CorrenStella E. LeeHaixin ZhangSivan HarelDanen CunoosamyAsif Hameed KhanJuby A. Jacob‐NaraShahid SiddiquiScott Nash et al.

Editorial material

Dupilumab efficacy in chronic rhinosinusitis with nasal polyps from SINUS‐52 is unaffected by eosinophilic status

Shigeharu FujiedaShoji MatsuneSachio TakenoNobuo OhtaMikiya AsakoClaus BachertTomoyuki InoueYoshinori TakahashiHiroyuki FujitaYamo Deniz et al.

A1 Journal Article in ALLERGY

Dupilumab in CRSwNP : responder analysis using clinically meaningful efficacy outcome thresholds

Chien‐Chia ChuangIsabelle GuilleminClaus BachertStella E. LeePeter HellingsWytske J. FokkensNicolas DuvergerChunpeng FanNadia DaizadehNikhil Amin et al.

A1 Journal Article in LARYNGOSCOPE

Dupilumab reduces asthma disease burden and recurrent SCS use in patients with CRSwNP and coexisting asthma

Mark GurnellAndrew Menzies-GowClaus BachertNjira LugogoSeong ChoShahid SiddiquiScott NashHaixin ZhangAsif Hameed KhanJuby Jacob Nara et al.

Dupilumab reduces asthma disease burden and recurrent SCS use in patients with CRSwNP and coexisting asthma

Mark GurnellAndrew Menzies-GowClaus BachertNjira LugogoSeong ChoShahid SiddiquiScott NashHaixin ZhangAsif Hameed KhanJuby Jacob Nara et al.

Efficacy and safety of benralizumab in chronic rhinosinusitis with nasal polyps : a randomized, placebo-controlled trial

Claus BachertJoseph K. HanMartin Y. DesrosiersPhilippe GevaertEnrico HefflerClaire HopkinsJody R. TverskyPeter BarkerDavid CohenClaire Emson et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Efficacy and safety of dupilumab in patients with uncontrolled severe CRSwNP and a clinical diagnosis of NSAID‐ERD : results from two randomized placebo‐controlled phase 3 trials

Joaquim MullolTanya M. LaidlawClaus BachertLeda P. MannentG. Walter CanonicaJoseph K. HanJorge F. MasperoCesar PicadoNadia DaizadehBenjamin Ortiz et al.

A1 Journal Article in ALLERGY

Empfehlungen zur Überprüfung der Wirksamkeit und Verlaufsdokumentation von Dupilumab bei chronischer Rhinosinusitis mit Nasenpolypen (CRSwNP) im deutschen Gesundheitssystem

L. KlimekU. Förster-RuhrmannH. OlzeA. G. BeuleA. M. ChakerJ. HagemannT. HuppertzT. K. HoffmannS. DazertT. Deitmer et al.

A2 Journal Article in LARYNGO-RHINO-OTOLOGIE

Estimating clinically meaningful change of efficacy outcomes in inadequately controlled chronic rhinosinusitis with nasal polyposis

Joseph K. HanClaus BachertStella E. LeeClaire HopkinsEnrico HefflerPeter HellingsAnju T. PetersSiddhesh KamatDiane WhalleyShanshan Qin et al.

A1 Journal Article in LARYNGOSCOPE

Evaluating treatment responses of dupilumab versus omalizumab in type 2 patients : the EVEREST trial

Lucia de Prado GomezAsif Hameed KhanAnju PetersClaus BachertMartin WagenmannEnrico HefflerClaire HopkinsPeter HellingsMei ZhangJun Xing et al.

Evaluating treatment responses of dupilumab versus omalizumab in type 2 patients : the EVEREST trial

Lucia de Prado GomezAsif Hameed KhanAnju PetersClaus BachertMartin WagenmannEnrico HefflerClaire HopkinsPeter HellingsMei ZhangJun Xing et al.

Granulocyte colony-stimulating factor : missing link for stratification of type 2-high and type 2-low chronic rhinosinusitis patients

Sharon Van NevelJozefien DeclercqGabriële HoltappelsBart LambrechtClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-10 family cytokines in chronic rhinosinusitis with nasal polyps : from experiments to the clinic

Lijia XuanNan ZhangXiangdong WangLuo ZhangClaus Bachert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Impact of dupilumab on SNOT-22 sleep and function scores in CRSwNP

William W. BusseAndrew WellmanZuzana DiamantNoam A. CohenAdam M. ChakerClaus BachertShahid SiddiquiHaixin ZhangScott NashAsif Hameed Khan et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Local immunoglobulin E in nasal polyps : role and modulation

Yang ShenNan ZhangYucheng YangSuling HongClaus Bachert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Long-term efficacy and safety of omalizumab for nasal polyposis in an open-label extension study

Philippe GevaertRebecca SaenzJonathan CorrenJoseph K. HanJoaquim MullolStella E. LeeRandall A. OwRui ZhaoMonet HowardKit Wong et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mepolizumab and benralizumab reduce eosinophilic inflammation in nasal polyposis, do neutrophils take over?

Tim DelemarreElien GevaertGabriële HoltappelsNan ZhangHans NauwynckClaus Bachert

Mepolizumab for chronic rhinosinusitis with nasal polyps : treatment efficacy by comorbidity and blood eosinophil count

Claus BachertAna R. SousaJoseph K. HanRodney J. SchlosserLeigh J. SowerbyClaire HopkinsJorge F. MasperoSteven G. SmithOliver KanteDespina E. Karidi-Andrioti et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Olfactory outcomes with dupilumab in chronic rhinosinusitis with nasal polyps

Joaquim MullolClaus BachertNikhil AminMartin DesrosiersPeter W HellingsJoseph K HanRoger JankowskiJan VodickaPhilippe GevaertNadia Daizadeh et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Online education yields significant gains in physicians' knowledge of eosinophil-associated disorders

Adriana StanGillian GriffithJuliette VandenbroucqueClaus Bachert

Phase 3b randomized controlled trial of fevipiprant in patients with nasal polyposis with asthma (THUNDER)

Philippe GevaertClaus BachertJorge Fernando MasperoMandy CuevasDavid SteeleSandip AcharyaPablo Altman

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Physical activity in asthma control and its immune modulatory effect in asthmatic preschoolers

Debbie J. MaurerChengyao LiuParaskevi XepapadakiBarbara StanicClaus BachertSusetta FinottoYa‐Dong GaoAnna GraserTuomas JarttiWalter Kistler et al.

A1 Journal Article in ALLERGY

Rapid and continuing improvements in nasal symptoms with dupilumab in patients with severe CRSwNP

Claus BachertAsif Hameed KhanClaire HopkinsMichael S. BlaissZachary M. SolerScott NashShahid SiddiquiAmy PraestgaardYamo DenizPaul J. Rowe et al.

A1 Journal Article in JOURNAL OF ASTHMA AND ALLERGY

Reboot surgery for chronic rhinosinusitis with nasal polyposis : recurrence and smell kinetics

Sara Costa GomesCarlo CavaliereSimonetta MasieriThibaut Van ZelePhilippe GevaertGabriële HoltappelsNan ZhangPathmanaban RamasamyRichard Louis VoegelsClaus Bachert

A1 Journal Article in EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Respiratory infections and anti-infective medication use from phase 3 dupilumab respiratory studies

Bob GengClaus BachertWilliam W. BussePhilippe GevaertStella E. LeeMichael S. NiedermanZhen ChenXin LuFaisal A. KhokharUpender Kapoor et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Responder analysis to demonstrate the effect of targeting type 2 inflammatory mechanisms with dupilumab across objective and patient‐reported endpoints for patients with severe chronic rhinosinusitis with nasal polyps in the SINUS‐24 and SINUS‐52 studies

Claus BachertAnju T. PetersEnrico HefflerJoseph K. HanHeidi OlzeOliver PfaarChien‐Chia ChuangRaj RoutRicha AttreLedia Goga et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Seasonal distribution of inhaled allergens in allergic asthma patients with or without allergic rhinitis

Ruxian TianYujuan YangLiping LiuYuemei SunNingbo TangYu ZhangNan ZhangXicheng SongClaus Bachert

A1 Journal Article in CHINESE MEDICAL JOURNAL

Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation

Olga KryskoJoshua H. BourneElena KondakovaElena A. GalovaKatharine WhitworthMaddy L. NewbyClaus BachertHarriet HillMax CrispinZania Stamataki et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Symptom free days in patients with severe chronic rhinosinusitis with nasal polyps treated with dupilumab

Claus BachertClaire HopkinsJoseph HanWytske FokkensLeda MannentAsif Hameed KhanJérôme MsihidUrvi MujumdarSiddhesh KamatScott Nash et al.

Symptom free days in patients with severe chronic rhinosinusitis with nasal polyps treated with dupilumab

Claus BachertClaire HopkinsJoseph HanWytske FokkensLeda MannentAsif Hameed KhanJerome MsihidUrvi MujumdarSiddhesh KamatScott Nash et al.

The protease SplB of staphylococcus aureus targets host complement components and inhibits complement-mediated bacterial opsonophagocytosis

Prasad DasariMaria NordengrünCláudia VilhenaLeif SteilGoran AbdurrahmanKristin SurmannVishnu DhopleJulia LahrbergClaus BachertChristine Skerka et al.

A1 Journal Article in JOURNAL OF BACTERIOLOGY

The roles of eosinophils and interleukin‐5 in the pathophysiology of chronic rhinosinusitis with nasal polyps

Philippe GevaertJoseph K. HanSteven G. SmithAna R. SousaPeter H. HowarthSteven W. YanceyRobert ChanClaus Bachert

A1 Journal Article in INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY

2021

A responder analysis to demonstrate Dupilumab treatment effect across objective and patient-reported subjective endpoints for patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP)

Claus BachertAnju PetersEnrico HefflerJoseph HanHeidi OlzeOliver PfaarChien-Chia ChuangRaj RoutRicha AttreLedia Goga et al.

A responder analysis to demonstrate dupilumab treatment effect across objective and patient-reported endpoints for patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP)

Claus BachertAnju T. PetersEnrico HefflerJoseph K. HanHeidi OlzeOliver PfaarShahid SiddiquiRaj Rout

A substantial neutrophilic inflammation as regular part of severe type 2 chronic rhinosinusitis with nasal polyps

Tim DelemarreGabriële HoltappelsNatalie De RuyckNan ZhangHans NauwynckClaus BachertElien Gevaert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

ARIA 2019 : um percurso assistencial integrado para a rinite alérgica em Portugal

Joao A. FonsecaTiago Taveira-GomesAna Margarida PereiraManuel Branco-FerreiraPedro Carreiro-MartinsMagna Alves-CorreiaJaime Correia de SousaElisio CostaOlga LourencoMario Morais-Almeida et al.

A1 Journal Article in ACTA MEDICA PORTUGUESA

ARIA 2019 care pathways for allergic rhinitis in the Kuwait health care system

Mona Al-AhmadJasmina NurkicClaus BachertOliver PfaarHolger J. SchunemannWienczyslawa CzarlewskiAnna BedbrookJean Bosquet

A1 Journal Article in MEDICAL PRINCIPLES AND PRACTICE

ARIA digital anamorphosis : digital transformation of health and care in airway diseases from research to practice

Jean BousquetJosep M. AntoClaus BachertTari HaahtelaTorsten ZuberbierWienczyslawa CzarlewskiAnna BedbrookSinthia Bosnic-AnticevichG. Walter CanonicaVictoria Cardona et al.

A1 Journal Article in ALLERGY

ARIA-EAACI statement on asthma and COVID-19 (June 2, 2020)

Jean BousquetMarek JutelCezmi A. AkdisLudger KlimekOliver PfaarKari C. NadeauThomas EiweggerAnna BedbrookIgnacio J. AnsoteguiJosep M. Anto et al.

A1 Journal Article in ALLERGY

ARIA‐EAACI care pathways for allergen immunotherapy in respiratory allergy

Jean BousquetOliver PfaarIoana AgacheAnna BedbrookCezmi A AkdisG. Walter CanonicaTomas ChivatoMona Al‐AhmadAmir H Abdul LatiffIgnacio J Ansotegui et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Allergen Immunotherapy management during vaccinations : an international survey

Simonetta MasieriClaus BachertPedro OjedaChang-Keun KimCarlo CavaliereGiorgio Ciprandi

A1 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

Allergien der oberen Atemwege

Ludger KlimekClaus Bachert

A2 Journal Article in ALLERGO JOURNAL

Artificial intelligence predicts severity of COVID-19 based on correlation of exaggerated monocyte activation, excessive organ damage and hyperinflammatory syndrome : a prospective clinical study

Olga KryskoElena KondakovaOlga VershininaElena GalovaAnna BlagonravovaEkaterina GorshkovaClaus BachertMikhail IvanchenkoDmitri KryskoMaria Vedunova

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Association between a type 2 inflammatory disease burden score and outcomes among patients with asthma

David PriceAndrew Menzies-GowClaus BachertGiorgio Walter CanonicaJanwillem KocksAsif H KhanFen YePaul J RoweYufang LuSiddhesh Kamat et al.

A1 Journal Article in JOURNAL OF ASTHMA AND ALLERGY

Association between dupilumab effect on nasal polyp score and biomarkers of type 2 inflammation in patients with chronic rhinosinusitis with nasal polyps in the phase 3 SINUS-24 and SINUS-52 trials

Claus BachertJ CorrenSE LeeH ZhangS HarelD CunoosamyAsif Hameed KhanJA Jacob-NaraS SiddiquiS Nash

Burden of disease in chronic rhinosinusitis with nasal polyps

Claus BachertNeil BhattacharyyaMartin DesrosiersAsif H. Khan

A1 Journal Article in JOURNAL OF ASTHMA AND ALLERGY

COVID‐19 pandemic : practical considerations on the organization of an allergy clinic : an EAACI/ARIA position paper

Oliver PfaarLudger KlimekMarek JutelCezmi A. AkdisJean BousquetHeimo BreitenederSharon ChinthrajahZuzana DiamantThomas EiweggerWytske J. Fokkens et al.

A1 Journal Article in ALLERGY

Cabbage and fermented vegetables : from death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

Jean BousquetSusana C. FonsecaAlain VidalAmir Hamzah Abdul LatiffBaharudin AbdullahWerner AbererNancy AbusadaIan AdcockAlejandro AfaniIoana Agache et al.

A1 Journal Article in ALLERGY

Cell death stage dictates the immunogenicity of ferroptotic cancer cells

Iuliia EfimovaElena CatanzaroRobin DemuynckLouis Van der MeerenFrauke CoppietersClaus BachertAndre SkirtachOlga KryskoDmitri Krysko

Clinical correlates of rhinovirus infection in preschool asthma

Tuomas JarttiUnna LiimatainenParaskevi XepapadakiTero VahlbergClaus BachertSusetta FinottoMarek L. KowalskiAnna SobanskaHeikki LukkarinenMaria Pasioti et al.

A1 Journal Article in ALLERGY

Clinical post-approval studies as part of the Therapy Allergen Regulation (TAV) : a systematic review

Andreas HornClaus BachertDetlef Brehmer

A2 Journal Article in ZEITSCHRIFT FUR EVIDENZ FORTBILDUNG UND QUALITAET IM GESUNDHEITSWESEN

Data mining of free-text responses : an innovative approach to analyzing patient perspectives on treatment for chronic rhinosinusitis with nasal polyps in a phase IIa proof-of-concept study for dupilumab

Asif H KhanAdeline AbbeBruno FalissardPaulo CaritaClaus BachertJoaquim MullolMatthew ReaneyJingdong ChaoLeda P MannentNikhil Amin et al.

A1 Journal Article in PATIENT PREFERENCE AND ADHERENCE

Differentiation of COVID‐19 signs and symptoms from allergic rhinitis and common cold : an ARIA‐EAACI‐GA(2)LEN consensus

Jan HagemannGabrielle L. OnoratoMarek JutelCezmi A. AkdisIoana AgacheTorsten ZuberbierWienczyslawa CzarlewskiJoaquim MullolAnna BedbrookClaus Bachert et al.

A1 Journal Article in ALLERGY

Digital Health Europe (DHE) twinning on severe asthma : kick-off meeting report

Jean BousquetAnna BedbrookWienczyslawa CzarlewskiGiuseppe De CarloJoao A. FonsecaMiguel A. González BallesterMaddalena IllarioSeppo KoskinenTiina LaatikainenGabrielle L. Onorato et al.

Dupilumab besitzt einen Zusatznutzen für die Behandlung der chronischen Rhinosinusitis mit Nasenpolypen

L. KlimekA. ChakerT. DeitmerS. K. PlontkeB. WollenbergJulie BousquetClaus Bachert

A1 Journal Article in HNO

Dupilumab improves upper and lower airway disease control in chronic rhinosinusitis with nasal polyps and asthma

Tanya M. LaidlawClaus BachertNikhil AminMartin DesrosiersPeter HellingsJoaquim MullolJorge F. MasperoPhilippe GevaertMei ZhangXuezhou Mao et al.

A1 Journal Article in ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Dupilumab reduces systemic corticosteroid use and sinonasal surgery rate in CRSwNP

M. DesrosiersL.P. MannentN. AminG.W. CanonicaPeter HellingsPhilippe GevaertJ. MullolS.E. LeeS. FujiedaJ.K. Han et al.

A1 Journal Article in RHINOLOGY

EUFOREA expert board meeting on uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) and biologics : definitions and management

Claus BachertJoe K. HanMartin WagenmannWerner HosemannStella E. LeeVibeke BackerJoaquim MullolPhilippe GevaertLudger KlimekEmanuel Prokopakis et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Early but not late ferroptotic cancer cells are immunogenic in vitro and in vivo

Iuliia EfimovaElena CatanzaroLouis Van der MeerenClaus BachertAndre SkirtachOlga KryskoDmitri Krysko

Efficacy of dupilumab in chronic rhinosinusitis with nasal polyps and comorbid asthma by baseline biomarkers of type 2 inflammation: SINUS-24 and SINUS-52 phase 3 trials

J. F. MasperoClaus BachertG. W. CanonicaB. N. SwansonS. H. ChoS. HarelA. JagerschmidtM. ZhangX. MaoL. P. Mannent et al.

Efficacy of dupilumab in patients with a history of prior sinus surgery for chronic rhinosinusitis with nasal polyps

Claire HopkinsMartin WagenmannClaus BachertMartin DesrosiersJoseph K. HanPeter W. HellingsStella E. LeeJerome MsihidAmr RadwanPaul Rowe et al.

A1 Journal Article in INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY

Extent of inflammation in severe nasal polyposis and effect of sinus surgery on inflammation

Karin JonstamSaeed AlsharifStijn BogaertNicole SuchonosGabriële HoltappelsJonas Jae-Hyun ParkClaus Bachert

A1 Journal Article in ALLERGY

Heterogeneity of the pharmacologic treatment of allergic rhinitis in Europe based on MIDAS and OTCims platforms

Jean BousquetDetlef Schröder‐BernhardiClaus BachertG. Walter CanonicaVictoria CardonaElisio M. CostaWienczyslawa CzarlewskiPhilippe DevillierJoao A. FonsecaLudger Klimek et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Immunogenic cell death in photodynamic-induced tumor cells based on photosens and photodithazine

Viktoria TurubanovaIuliia EfimovaTatiana MishchenkoElena CatanzaroIrina BalalaevaClaus BachertOlga KryskoMaria VedunovaDmitri Krysko

Impact of dupilumab on sleep/function scores in patients with chronic rhinosinusitis with nasal polyps

W BusseA WellmanClaus BachertS SiddiquiH ZhangAsif Hameed KhanJ Jacob-NaraP RoweY Deniz

Indirect treatment comparison of biologics in chronic rhinosinusitis with nasal polyps

Anju T. PetersJoseph K. HanPeter HellingsEnrico HefflerPhilippe GevaertClaus BachertYingxin XuChien-Chia ChuangBinod NeupaneJérôme Msihid et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

International consensus statement on allergy and rhinology : rhinosinusitis 2021

Richard R. OrlandiTodd T. KingdomTimothy L. SmithBenjamin BleierAdam DeCondeAmber U. LuongDavid M. PoetkerZachary SolerKevin C. WelchSarah K. Wise et al.

A1 Journal Article in INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY

Involvement of the extracellular matrix proteins periostin and tenascin C in nasal polyp remodeling by regulating the expression of MMPs

Kun DuMin WangNan ZhangPei YuPing WangYing LiXiangdong WangLuo ZhangClaus Bachert

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Management of anaphylaxis due to COVID‐19 vaccines in the elderly

Jean BousquetIoana AgacheHubert BlainMarek JutelMaria Teresa VenturaMargitta WormStefano Del GiaccoAthanasios BenetosMaria Beatrice BiloWienczyslawa Czarlewski et al.

A1 Journal Article in ALLERGY

Management of patients with chronic rhinosinusitis during the COVID-19 pandemic : an EAACI position paper

Ludger KlimekMarek JutelJean BousquetIoana AgacheCezmi A. AkdisValerie HoxPhilippe GevaertPeter Valentin TomazicCarmen RondonCemal Cingi et al.

A1 Journal Article in ALLERGY

Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE) : a randomised, double-blind, placebo-controlled, phase 3 trial

Joseph K HanClaus BachertWytske FokkensMartin DesrosiersMartin WagenmannStella E LeeSteven G SmithNeil MartinBhabita MayerSteven W Yancey et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

Mepolizumab reduces disease symptoms for patients with chronic rhinosinusitis with nasal polyps : data from the SYNAPSE study

Maggie TabbererAndrew TriggWilliam BusseValerie LundJason LeeClaus BachertBrent SeniorKathleen BuchheitZuzana DiamantAna Sousa et al.

Neutrophils affect IL-33 processing in response to the respiratory allergen Alternaria alternata

Sharon Van NevelJudith van OvostGabriële HoltappelsNatalie De RuyckNan ZhangHarald BraunTania MaesClaus BachertOlga Krysko

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Novel porphyrazine-based photodynamic anti-cancer therapy induces immunogenic cell death

Victoria D. TurubanovaTatiana A. MishchenkoV Balalaeva, IrinaIuliia EfimovaNina N. PeskovaLarisa G. KlapshinaSvetlana A. LermontovaClaus BachertOlga KryskoMaria V. Vedunova et al.

A1 Journal Article in SCIENTIFIC REPORTS

Omalizumab or dupilumab for chronic rhinosinusitis with nasal polyposis Reply

Philippe GevaertJonathan CorrenJoaquim MullolJoseph HanStella E. LeeMonica Ligueros-SaylanKit WongTheodore A. OmachiClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Personalized medicine for allergy treatment : allergen immunotherapy still a unique and unmatched model

Cristoforo IncorvaiaMona Al-AhmadIgnacio J. AnsoteguiStefania ArasiClaus BachertCatherine BosJean BousquetAndrzej BozekDavide CaimmiMoises A. Calderon et al.

A1 Journal Article in ALLERGY

Physiology and pathology of eosinophils : recent developments summary of the Focus Workshop organized by DGAKI

Harald RenzClaus BachertClaudia BerekEckard HamelmannFrancesca Levi-SchafferUlrike RaapHans-Uwe SimonSabine PloetzChristian TaubePeter Valent et al.

A1 Journal Article in SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Reducing fungal exposure critical for treating rhinosinusitis with or without polyps [response to letter]

Claus BachertNeil BhattacharyyaMartin DesrosiersAsif Hameed Khan

A1 Journal Article in JOURNAL OF ASTHMA AND ALLERGY

Regulated on activation, normal T cell expressed and secreted (RANTES) drives the resolution of allergic asthma

Nina LiHoomann MirzakhaniAlexander KieferJulia KoelleTytti VuorinenManfred RauhZuqin YangSusanne KrammerParaskevi XepapadakiAnna Lewandowska-Polak et al.

A1 Journal Article in ISCIENCE

Reply to 'type 2 chronic rhinosinusitis with nasal polyps : from phenotype to endotype'

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Rethinking neutrophils and eosinophils in chronic rhinosinusitis

Tim DelemarreBruce S. BochnerHans-Uwe SimonClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Role of biologics in chronic rhinosinusitis with nasal polyposis : state of the art review

Christine KimJoseph HanTara WuClaus BachertWytske FokkensPeter HellingsClaire HopkinsStella LeeJoaquim MullolJivianne T. Lee

A1 Journal Article in OTOLARYNGOLOGY-HEAD AND NECK SURGERY

Single-cell analysis pinpoints distinct populations of cytotoxic CD4(+) T cells and an IL-10(+)CD109(+)TH2 cell population in nasal polyps

Junjie MaChristopher A. TibbittSusanna Kumlien GeorénMurray ChristianBen MurrellLars-Olaf CardellClaus BachertJonathan M. Coquet

A1 Journal Article in SCIENCE IMMUNOLOGY

Surgery in nasal polyp patients : outcome after a minimum observation of 10 years

Stephan VlaminckFrederic AckeEmmanuel ProkopakisKato SpelemanHideyuki KawauchiJean-Christophe van CutsemPeter HellingsMark JorissenSven SeysClaus Bachert et al.

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY & ALLERGY

The SP‐TLR axis, which locally primes the nasal mucosa, is impeded in patients with allergic rhinitis

Olivia LarssonOla SunnergrenClaus BachertSusanna Kumlien GeorénLars Olaf Cardell

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Type 2 inflammatory shift in chronic rhinosinusitis during 2007-2018 in Belgium

K JonstamTim DelemarreGabriële HoltappelsLars-Olaf CardellM WestmanClaus Bachert

A1 Journal Article in LARYNGOSCOPE

What is the contribution of IgE to nasal polyposis?

Claus BachertMarcus MaurerOscar PalomaresWilliam W. Busse

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

2020

Adult chronic rhinosinusitis

Claus BachertBradley MarpleRodney J. SchlosserClaire HopkinsRobert P. SchleimerBart LambrechtBarbara M. BrokerTanya LaidlawWoo-Jung Song

A1 Journal Article in NATURE REVIEWS DISEASE PRIMERS

Aligning the good practice MASK with the objectives of the European Innovation Partnership on Active and Healthy Ageing

J. BousquetJ. FarrellM. IllarioG. L. OnoratoA. BedbrookW. CzarlewskiY. MicheliS. ArnavielheI. J. AnsoteguiJ. M. Anto et al.

A1 Journal Article in ALLERGY ASTHMA & IMMUNOLOGY RESEARCH

Allergic respiratory disease care in the COVID-19 era : a EUFOREA statement

Glenis K. ScaddingPeter HellingsClaus BachertLeif BjermerZuzana DiamantPhilippe GevaertAnette KjeldsenJorge Kleine-TebbeLudger KlimekAntonella Muraro et al.

A1 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

Allergic rhinitis

Jean BousquetJosep M. AntoClaus BachertIlaria BaiardiniSinthia Bosnic-AnticevichG. Walter CanonicaErik MelenOscar PalomaresGlenis K. ScaddingAlkis Togias et al.

A1 Journal Article in NATURE REVIEWS DISEASE PRIMERS

Allergy : a new role for T cell superantigens of Staphylococcus aureus?

Goran AbdurrahmanFrieder SchmiedekeClaus BachertBarbara M. BroekerSilva Holtfreter

A1 Journal Article in TOXINS

An underestimated predictive role for Type 2 inflammation in CRSsNP

Tim DelemarreGabriële HoltappelsNatalie De RuyckClaus BachertElien Gevaert

Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis : an EAACI position paper

Valerie HoxEvelijn LourijsenArnout JordensKristian AasbjergIoana AgacheIsam AlobidClaus BachertKoen BousseryPaloma CampoWytske Fokkens et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis : an EAACI position paper (vol 10, 1, 2020)

Valerie HoxEvelijn LourijsenArnout JordensKristian AasbjergIoana AgacheIsam AlobidClaus BachertKoen BousseryPaloma CampoWytske Fokkens et al.

Biologics for chronic rhinosinusitis with nasal polyps

Claus BachertNan ZhangCarlo CavaliereWen Weiping Wen WeipingElien GevaertOlga Krysko

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

COVID-19 in a patient with severe chronic rhinosinusitis with nasal polyps during therapy with dupilumab

Ulrike Foerster-RuhrmannAgnieszka J. SzczepekClaus BachertHeidi Olze

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis

Elien GevaertTim DelemarreJoyceline De VolderNan ZhangGabriële HoltappelsNatalie De RuyckEmma PerssonInes HeyndrickxKenneth VerstraeteHelena Catharine Aegerter et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Chronic rhinosinusitis : assessment of changes in nociceptive neurons

Stijn BogaertKoen Van CrombruggenGabriële HoltappelsNatalie De RuyckNicole SuchonosJonas Jae-Hyun ParkClaus Bachert

A1 Journal Article in INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY

Clinical research needs for the management of chronic rhinosinusitis with nasal polyps in the new era of biologics : a National Institute of Allergy and Infectious Diseases workshop

Robert NaclerioFuad BaroodyClaus BachertBenjamin BleierLarry BorishErica BrittainGeoffrey ChuppAnat FisherWytske FokkensPhilippe Gevaert et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Continued safety / efficacy of omalizumab in chronic rhinosinusitis with nasal polyps : an open-label extension study

Philippe GevaertR. SaenzJ. CorrenJ. HanJ. MullolS. LeeR. ZhaoM. HowardK. WongL. Islam et al.

Correlation between work impairment, scores of rhinitis severity and asthma using the MASK-air (R) App

Annabelle BedardJosep M. AntoJoao A. FonsecaSylvie ArnavielheClaus BachertAnna BedbrookCarsten Bindslev-JensenSinthia Bosnic-AnticevichVictoria CardonaAlvaro A. Cruz et al.

A1 Journal Article in ALLERGY

Deposition characteristics of a novel intranasal formulation of azelastine hydrochloride plus fluticasone propionate in an anatomic model of the human nasal cavity

Eli O. MeltzerClaus BachertMichael J. MayerFerdinand KopietzArkady KoltunJoachim MausAlexander D. D'Addio

A1 Journal Article in ALLERGY AND ASTHMA PROCEEDINGS

Differential response of C57BL/6 and BALB/c mice in Alternaria alternata-induced allergic airway inflammation

Sharon Van NevelNatalie De RuyckGabriële HoltappelsClaus BachertOlga Krysko

Dupilumab for nasal polyposis : authors' reply

Claus BachertLeda P. Mannent

A1 Journal Article in LANCET

Dupilumab improves asthma control as assessed by total and individual item scores of the 6-item asthma control questionnaire in patients with severe chronic rhinosinusitis with nasal polyps and comorbid asthma : pooled results from the SINUS-24 and SINUS-52 phase 3 studies

Claus BachertJK HanM DesrosiersPW HellingsX MaoM ZhangN AminLP MannentS KamatAsif Hameed Khan

Dupilumab improves health‐related quality of life in patients with chronic rhinosinusitis with nasal polyposis

Claus BachertPeter HellingsJoaquim MullolDaniel L HamilosPhilippe GevaertRobert M NaclerioVijay N JoishJingdong ChaoLeda P MannentNikhil Amin et al.

A1 Journal Article in ALLERGY

Dupilumab is associated with lower rates of respiratory infections in patients with chronic rhinosinusitis with nasal polyps-Safety analysis from the SINUS-52 phase 3 trial

Claus BachertPhilippe GevaertS. E. LeeN. Kanesa-ThasanS. GreenL. P. MannentN. AminZ. ChenX. LuN. Pandit-Abid et al.

Dupilumab rapidly improves sense of smell in patients with severe chronic rhinosinusitis with nasal polyps : pooled results from the SINUS-24 and SINUS-52 phase 3 studies

J. MullolClaus BachertM. DesrosiersJ. K. HanR. JankowskiN. DaizadehN. AminL. P. MannentAsif Hameed KhanS. Kamat

Dupilumab reduces blood and nasal biomarkers of type 2 inflammation in patients with chronic rhinosinusitis with nasal polyps with and without comorbid asthma : SINUS-52 trial

Claus BachertJoaquim MullolNadia DaizadehKelley WolfeBenjamin OrtizRobert JohnsonYamo DenizPaul RoweLeda MannentNikhil Amin et al.

Dupilumab reduces opacification across all sinuses and related symptoms in patients with CRSwNP

Claus BachertS James ZinreichPeter HellingsJoaquim MullolDaniel L HamilosPhilippe GevaertRobert M NaclerioNikhil AminVikay N JoishChunpeng Fan et al.

A1 Journal Article in RHINOLOGY

Efficacy and safety of omalizumab in nasal polyposis : 2 randomized phase 3 trials

Philippe GevaertTheodore A. OmachiJonathan CorrenJoaquim MullolJoseph HanStella E. LeeDerrick KaufmanMonica Ligueros-SaylanMonet HowardRui Zhu et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Endotypes of chronic rhinosinusitis : impact on management

Lars-Olaf CardellPar StjarneKarin JonstamClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Endotypes of chronic rhinosinusitis with nasal polyps : pathology and possible therapeutic implications

Claus BachertBrad MarpleWerner HosemannCarlo CavaliereWeiping WenNan Zhang

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Eosinophil paradox with mepolizumab in chronic rhinosinusitis with nasal polyposis : reply

Peter HowarthClaus BachertAna SousaRobert Chan

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

European position paper on rhinosinusitis and nasal polyps 2020

W. J. FokkensV. J. LundC. HopkinsPeter HellingsR. KernS. ReitsmaS. Toppila-SalmiM. Bernal-SprekelsenJ. MullolI. Alobid et al.

A1 Journal Article in RHINOLOGY

European position paper on rhinosinusitis and nasal polyps 2020

Wytske J. FokkensValerie J. LundClaire HopkinsPeter HellingsRobert KernSietze ReitsmaSanna Toppila-SalmiManuel Bernal-SprekelsenJoaquim MullolIsam Alobid et al.

A1 Journal Article in RHINOLOGY

Evaluating the real-life effect of MP-AzeFlu on asthma control in patients with allergic rhinitis and asthma in UK primary care

H. De JongR. MurrayV CarterD. RyanG. ScaddingW. CanonicaP. SmithU. WahnJ. A. CastilloClaus Bachert et al.

Evaluating the real-life effect of MP-AzeFlu on asthma outcomes in patients with allergic rhinitis and asthma in UK primary care

Hilda J. I. De JongJaco VoorhamGlenis K. ScaddingClaus BachertGiorgio Walter CanonicaPeter SmithUlrich WahnDermot RyanJose A. CastilloVictoria A. Carter et al.

A1 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

Evaluation of in vitro penetration of fluticasone propionate from MP-AzeFlu and fluticasone propionate nasal spray through EpiAirway (TM) 606 tissues using vertical diffusion cells

William E. BergerClaus BachertRobert AllaraArkady KoltunFerdinand KopietzJoachim G. MausAlexander D. D'Addio

A1 Journal Article in JOURNAL OF ASTHMA AND ALLERGY

Evolution of airway inflammation in preschoolers with asthma : results of a two-year longitudinal study

Paraskevi XepapadakiParaskevi KorovessiClaus BachertSusetta FinottoTuomas JarttiJohn LakoumentasMarek L. KowalskiAnna Lewandowska-PolakHeikki LukkarinenNan Zhang et al.

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

Evolution of airway inflammation in preschoolers with asthma-results of a two-year longitudinal study

P. XepapadakiP. KorovessiClaus BachertS. FinottoT. JarttiJ. LakoumentasM. L. KowalskiA. Lewandowska-PolakH. LukkarinenNan Zhang et al.

Functional characterization of the first missense variant in CEP78, a founder allele associated with cone‐rod dystrophy, hearing loss and reduced male fertility

Giulia AscariFrank PeelmanPietro FarinelliToon RosseelNina LambrechtsKirsten A. WunderlichMatias WagnerKonstantinos NikopoulosPernille MartensIrina Balikova et al.

A1 Journal Article in HUMAN MUTATION

Glukokortikoide und Covid-19

Ludger KlimekUlrike Förster-RuhrmannSven BeckerAdam ChakerTilman HuppertzThomas DeitmerHeidi OlzeSebastian StriethMargitta WormEckard Hamelmann et al.

Editorial material

Handling of allergen immunotherapy in the COVID-19 pandemic : an ARIA-EAACI statement

Ludger KlimekMarek JutelCezmi AkdisJean BousquetMubeccel AkdisClaus BachertIoana AgacheIgnacio AnsoteguiAnna BedbrookSinthia Bosnic-Anticevich et al.

A1 Journal Article in ALLERGY

Identification of a novel pathway in immune response towards S. aureus protease like protein D

Olga KryskoAndrea Renate TeufelbergerSharon Van NevelSzanne De GraevePaco HulpiauM. NordengruenB. M. BroekerDmitri KryskoClaus Bachert

Impaired small airway function in non-asthmatic chronic rhinosinusitis with nasal polyps

Kun DuMing ZhengYan ZhaoWenbin XuYun HaoYue WangJinming ZhaoNan ZhangXiangdong WangLuo Zhang et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Indirect treatment comparison of biologics used for the treatment of chronic rhinosinusitis with nasal polyps

A. PetersJ. HanP. HellingsE. HefflerPhilippe GevaertClaus BachertY. XuC. ChuangL. MannentP. Guyot et al.

Intranasal corticosteroids in allergic rhinitis in COVID-19 infected patients : an ARIA-EAACI statement

Jean BousquetCezmi A. AkdisMarek JutelClaus BachertLudger KlimekIoana AgacheIgnacio J. AnsoteguiAnna BedbrookSinthia Bosnic-AnticevichG. Walter Canonica et al.

A1 Journal Article in ALLERGY

Late breaking abstract : add-on mepolizumab for chronic rhinosinusitis with nasal polyps : SYNAPSE study

Claire HopkinsClaus BachertWytske FokkensMartin DesrosiersMartin WagenmannStella LeeAna SousaSteven SmithNeil MartinBhabita Mayer et al.

Linking complement C3 and B cells in nasal polyposis

Ulrike WernerAxel KuenstnerMaren DrenckhanRalph PriesKarl-Ludwig BruchhageHauke S. BuschClaus BachertBarbara Wollenberg

A1 Journal Article in JOURNAL OF IMMUNOLOGY RESEARCH

Managing allergic rhinitis in the pharmacy : an ARIA guide for implementation in practice

Olga LourencoSinthia Bosnic-AnticevichElisio CostaJoao A. FonsecaEnrica MendittoBiljana CvetkovskiVicky KritikosRachel TanAnna BedbrookSophie Scheire et al.

A2 Journal Article in PHARMACY

Mouse strain-dependent difference toward the staphylococcus aureus allergen serine protease-like protein D reveals a novel regulator of IL-33

Andrea Renate TeufelbergerSharon Van NevelPaco HulpiauMaria NordengrünSavvas SavvidesSarah De GraeveSrinivas AkulaGabriële HoltappelsNatalie De RuyckWim Declercq et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Nasal IgE in subjects with allergic and non-allergic rhinitis

Jonas EckrichJulia HinkelAnna FischlEva HerrmannGabriële HoltappelsClaus BachertStefan Zielen

A1 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

Next-generation Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence

Jean BousquetHolger J SchünemannAkdis TogiasClaus BachertMartina ErholaPeter HellingsLudger KlimekOliver PfaarDana WallaceIgnacio Ansotegui et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Next-generation allergic rhinitis care in Singapore : 2019 ARIA care pathways

Xuandao LiuDe Yun WangTze Choong CharnLeslie Timothy KohNeville W. Y. TeoYew Kwang OngMark K. T. ThongClaus BachertOliver PfaarHolger J. Schunemann et al.

A1 Journal Article in ANNALS ACADEMY OF MEDICINE SINGAPORE

Nrf2-interacting nutrients and COVID-19 : time for research to develop adaptation strategies

Jean BousquetJean-Paul CristolAdrian MartineauSusana C. FonsecaAlain VidalHak-Jong ChoiHyun Ju KimVincent Le MoingJacques ReynesAmir Hamzah Abdul Latiff et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Omalizumab improves outcomes in patients with chronic rhinosinusitis with nasal polyps irrespective of asthma status

Claus BachertPhilippe GevaertJonathan CorrenJoaquim MullolJoseph HanRandall OwSanna Toppila-SalmiIsam AlobidDerrick KaufmanBongin Yoo et al.

Omalizumab improves quality of life in patients with chronic rhinosinusitis with nasal polyps and comorbid asthma

Jonathan CorrenClaus BachertPhilippe GevaertJoaquim MullolJoseph HanRandall OwSanna Toppila-SalmiIsam AlobidDerrick KaufmanJessica Braid et al.

Omalizumab responders analysis in nasal polyposis : a supplementary analysis of the co-primary endpoints of POLYP 1 and POLYP 2 trials

J. CorrenP. H. WellingsPhilippe GevaertClaus BachertJ. MullolX. JaumontR. ZhaoR. SaenzL. IslamT. Omachi

Perspective : COVID-19, implications of nasal diseases and consequences for their management

Li JianWei YiNan ZhangWeiping WenOlga KryskoWoo-Jung SongClaus Bachert

Editorial material

Positionspapier : Anwendung von Biologika bei chronischer Rhinosinusitis mit Polyposis nasi (CRSwNP) im deutschen Gesundheitssystem : Empfehlungen des Ärzteverbandes Deutscher Allergologen (AeDA) und der AGs Klinische Immunologie, Allergologie und Umweltmedizin und Rhinologie und Rhinochirurgie der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC)

L. KlimekU. Forster-RuhrmannS. BeckerA. ChakerS. StriethT. K. HoffmannS. DazertT. DeitmerH. OlzeA. Glien et al.

A1 Journal Article in LARYNGO-RHINO-OTOLOGIE

Positionspapier : Empfehlungen zur Behandlung der chronischen Rhinosinusitis während der COVID-19-Pandemie im deutschen Gesundheitssystem : Empfehlungen des Ärzteverbandes Deutscher Allergologen (AeDA) und der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Halschirurgie (DGHNO-KHC) : Diese Empfehlungen basieren auf dem EAACI Positionspapier 'Treatment of chronic rhinosinusitis with nasal polyps (CRSwNP) in the COVID-19 pandemics : an EAACI position paper', Allergy, 2020 und wurden auf die Situation im deutschen Gesundheitswesen angepasst

L. KlimekS. BeckerR. BuhlA. M. ChakerT. HuppertzT. K. HoffmannS. DazertT. DeitmerU. Förster-RuhrmannH. Olze et al.

A1 Journal Article in LARYNGO-RHINO-OTOLOGIE

Positionspapier : Hinweise zur Patienteninformation und -aufklärung vor Anwendung von Biologika bei chronischer Rhinosinusitis mit Polyposis nasi (CRSwNP)* : Empfehlungen des Ärzteverbandes Deutscher Allergologen (AeDA) und der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC) : Teil 1 : Dupilumab

L. KlimekA. G. BeuleU. Foerster-RuhrmannS. BeckerA. ChakerT. HuppertzJ. HagemannT. K. HoffmannS. DazertT. Deitmer et al.

A1 Journal Article in LARYNGO-RHINO-OTOLOGIE

Real-life assessment of chronic rhinosinusitis patients using mobile technology : the mySinusitisCoach project by EUFOREA

Sven F. SeysShana De BontWytske J. FokkensClaus BachertIsam AlobidManuel Bernal-SprekelsenLeif BjermerIna CallebautLars-Olaf CardellSean Carrie et al.

A1 Journal Article in ALLERGY

Rhinology Future Debates 2018, a EUFOREA report

Emmanuel ProkopakisAlexios VardouniotisClaus BachertJean BousquetSean CarriePaolo CastelnuevoJannis ConstantinidisWytske FokkensClaire HopkinsAndreas Leunig et al.

A1 Journal Article in RHINOLOGY

Severe eosinophilic asthma with nasal polyposis : a phenotype for improved sinonasal and asthma outcomes with mepolizumab therapy

Peter HowarthGeoffrey ChuppLinda M. NelsenEric S. BradfordDaniel J. BrattonSteven G. SmithFrank C. AlbersGuy BrusselleClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Stability of regulatory T cells in T helper 2-biased allergic airway diseases

Feng LanNan ZhangClaus BachertLuo Zhang

A1 Journal Article in ALLERGY

Staphylococcus aureus and its IgE-inducing enterotoxins in asthma : current knowledge

Claus BachertMarc HumbertNicola A. HananiaNan ZhangStephen HolgateRoland BuhlBarbara M. Broeker

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Stellungnahme zur Anwendung von Glukokortikosteroiden bei entzündlichen Erkrankungen der oberen Atemwege (u. a. allergische Rhinitis/chronische Rhinosinusitis) während der aktuellen COVID-19-Pandemie : Empfehlungen des Ärzteverbandes Deutscher Allergologen (AeDA), des Deutschen Berufsverbandes der HNO-Ärzte (BVHNO) und der AGs Klinische Immunologie, Allergologie und Umweltmedizin und Rhinologie und Rhinochirurgie der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Halschirurgie (DGHNO-KHC)

L. KlimekU. Foerster-RuhrmannS. BeckerA. ChakerT. HuppertzT. DeitmerH. OlzeS. StriethH. WredeW. Schlenter et al.

Editorial material

The role of regulated on activation, normal T cell expressed and secreted (RANTES) in allergic asthma

N. LiJ. KoelleA. KieferP. XepapadakiM. L. KowalskiClaus BachertT. JarttiT. VuorinenA. Lewandowska-PolakNan Zhang et al.

Translational research into the effects of cigarette smoke on inflammatory mediators and epithelial TRPV1 in Crohn’s disease

Liesbeth AllaisStephanie VerschuereTania MaesRebecca De SmetSarah DevrieseGerard GonzalesHarald PeetersKoen Van CrombruggenClaus BachertMartine De Vos et al.

A1 Journal Article in PLOS ONE

Treatment of allergic rhinitis during and outside the pollen season using mobile technology : a MASK study

A. BedardX. BasaganaJ. M. AntoJ. Garcia-AymerichP. DevillierS. ArnavielheA. BedbrookG. L. OnoratoW. CzarlewskiR. Murray et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Type 2 inflammation in chronic rhinosinusitis without nasal polyps : another relevant endotype

Tim DelemarreGabriële HoltappelsNatalie De RuyckNan ZhangHans NauwynckClaus BachertElien Gevaert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Unravelling the expression of interleukin-9 in chronic rhinosinusitis : a possible role for Staphylococcus aureus

Tim DelemarreNatalie De RuyckGabriële HoltappelsClaus BachertElien Gevaert

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity

Iuliia EfimovaElena CatanzaroLouis Van der MeerenVictoria TurubanovaHamida HammadTatiana MishchenkoMaria VedunovaCarmela FimognariClaus BachertFrauke Coppieters et al.

A1 Journal Article in JOURNAL FOR IMMUNOTHERAPY OF CANCER

mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice

Lien Van HoeckeRein VerbekeDorien De VliegerHeleen DewitteKenny RooseSharon Van NevelOlga KryskoClaus BachertBert SchepensIne Lentacker et al.

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

2019

2019 ARIA : care pathways for allergic rhinitis - Poland

Boleslaw SamolinskiEdyta Krzych-FaltaBarbara PiekarskaAgnieszka LipiecPiotr KunaMaciej KupczykMarek JutelMarek NiedoszytkoEwa JassemMarek L. Kowalski et al.

A2 Journal Article in ALERGOLOGIA POLSKA-POLISH JOURNAL OF ALLERGOLOGY

2019 ARIA Care pathways for allergen immunotherapy

Jean BousquetOliver PfaarAlkis TogiasHolger J SchünemannIgnacio AnsoteguiNikolaos G PapadopoulosIoanna TsiligianniIoana AgacheJosep M AntoClaus Bachert et al.

A1 Journal Article in ALLERGY

A randomized phase 3 study, SINUS-52, evaluating the efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps

Claus BachertMartin DesrosiersJoaquim MullolPeter HellingsAnders CervinLawrence SherJohn V BossoStella E LeeJorge F MasperoShigeharu Fujieda et al.

ARIA-Versorgungspfade für die Allergenimmuntherapie 2019 = 2019 ARIA Care pathways for allergen immunotherapy

J. BousquetO. PfaarA. TogiasH.J. SchünemannI AnsoteguiN.G. PapadopoulosI TsiligianniI AgacheJM antoClaus Bachert et al.

A1 Journal Article in ALLERGOLOGIE

ARIApharmacy 2018 'Allergic rhinitis care pathways for community pharmacy'

Sinthia Bosnic‐AnticevichElisio CostaEnrica MendittoOlga LourençoEttore NovellinoSlawomir BialekVitalis BriedisRoland BuonaiutoHenry ChrystynBiljana Cvetkovski et al.

A1 Journal Article in ALLERGY

Adherence to treatment in allergic rhinitis using mobile technology : the MASK study

Enrica MendittoElisio CostaLuis MidãoSinthia Bosnic‐AnticevichEttore NovellinoSlawomir BialekVitalis BriedisAlpana MairRojin Rajabian‐SoderlundSylvie Arnavielhe et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Allergic Rhinitis and its Impact on Asthma (ARIA) phase 4 (2018) : change management in allergic rhinitis and asthma multimorbidity using mobile technology

Jean BousquetPeter W HellingsIoana AgacheFlore AmatIsabella Annesi-MaesanoIgnacio J AnsoteguiJosep M AntoClaus BachertEric D BatemanAnna Bedbrook et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Baseline characteristics of patients with chronic rhinosinusitis with nasal polyps (with and without asthma) enrolled in SINUS-52 : a randomized, double-blind, phase 3 study of dupilumab

Claus BachertM DesrosiersJ MullolJF MasperoM WagenmannI NiemannAsif Hameed KhanS KamatN AminLP Mannent

Baseline characteristics of phase 3 randomized controlled trials of omalizumab in chronic rhinosinusitis with nasal polyps

Claus BachertPhilippe GevaertJ CorrenJ MullolJ HanR OwI HussainL IslamR FogelD Kaufman et al.

Baseline-Charakteristika von Patienten mit chronischer Rhinosinusitis mit nasalen Polypen (mit und ohne Asthma) in SINUS-52 : einer randomisierten, doppel-blinden, Phase-3-Studie von Dupilumab

Claus BachertM DesrosiersJ MullolJF MasperoM WagenmannI NiemannAsif Hameed KhanS KamatN AminLP Mannent

Biologics for the treatment of chronic rhinosinusitis with nasal polyps : state of the art

Lei RenNan ZhangLuo ZhangClaus Bachert

A1 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

Biologika in der Behandlung der chronischen Rhinosinusitis mit Nasenpolypen : Aktueller Stand

Nan ZhangClaus Bachert

A1 Journal Article in ALLERGOLOGIE

Broad IgG repertoire in patients with chronic rhinosinusitis with nasal polyps regulates proinflammatory IgE responses

Mohamed H ShamjiIrene ThomsenJanice A LayhadiJasper KappenGabriële HoltappelsUmit SahinerAmy SwitzerStephen R DurhamOliver PabstClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Chronic rhinosinusitis with nasal polyps in older adults : clinical presentation, pathophysiology, and comorbidity

Woo-Jung SongJi-Hyang LeeHa-Kyeong WonClaus Bachert

A1 Journal Article in CURRENT ALLERGY AND ASTHMA REPORTS

Comparison of a new Skin Prick Test Tape with the conventional skin prick test

Zhengpeng GongZhijie YangRan WuHuiping YeMin JiaNan ZhangClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Conjunctivitis in dupilumab clinical trials

B. AkinladeE. Guttman‐YasskyM. Bruin‐WellerE.L. SimpsonA. BlauveltM.J. CorkE. PrensP. AsbellE. AkpekJ. Corren et al.

A1 Journal Article in BRITISH JOURNAL OF DERMATOLOGY

Cross-talk between TH2 and TH17 pathways in patients with chronic rhinosinusitis with nasal polyps

Min WangNan ZhangMing ZhengYing LiLingling MengYu RuanJinbo HanNa ZhaoXiangdong WangLuo Zhang et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Development and characterization of DNAzyme candidates demonstrating significant efficiency against human rhinoviruses

Daniel P PotaczekSebastian D UngerNan ZhangStyliani TakaSven MichelNesibe AkdağFeng LanMarkus HelferChristoph HudemannMarkus Eickmann et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Development of antirhinoviral DNAzymes for effective prevention of asthma exacerbations

Daniel P PotaczekSebastian D UngerNan ZhangStyliani TakaSven MichelNesibe AkdagFeng LanMarkus HelferChristoph HudemannMarkus Eickmann et al.

Differentiating eosinophil and neutrophil inflammation in chronic rhinosinusitis with and without nasal polyps

Tim DelemarreGabriële HoltappelsNatalie De RuyckClaus BachertElien Gevaert

Dupilumab efficacy in patients with severe chronic rhinosinusitis with nasal polyposis : pooled results from the SINUS-24 and SINUS-52 phase 3 studies

Claus BachertWJ FokkensR JankowskiAU CervinTM LaidlawSE LeeM ZhangX LuN AminN Patel et al.

Dupilumab improves patient-reported outcomes in chronic Rhinosinusitis with nasal polyps and comorbid asthma : sinus-24/sinus-52 trials

Philippe GevaertClaus BachertM. DesrosiersJ. MullolJ. MasperoM. ZhangX. MaoS. KamatA. KhanN. Amin et al.

Dupilumab improves patient-reported outcomes in patients with chronic rhinosinusitis with nasal polyps and comorbid asthma

Claus BachertPeter HellingsJoaquim MullolRobert M NaclerioJingdong ChaoNikhil AminAnnette GrabherBrian N SwansonJennifer D HamiltonSophie Guillonneau et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Dupilumab reduces local type 2 pro-inflammatory biomarkers in chronic rhinosinusitis with nasal polyposis

Karin JonstamBrian N SwansonLeda P MannentLars-Olaf CardellNian TianYing WangDonghui ZhangChunpeng FanGabriële HoltappelsJennifer D Hamilton et al.

A1 Journal Article in ALLERGY

Dupilumab reduces need for systemic corticosteroid use, sinonasal surgery in patients with severe chronic rhinosinusitis with nasal polyps : pooled results from the SINUS- 24, SINUS- 52 phase 3 studies

M DesrosiersClaus BachertPeter HellingsC HopkinsH OlzeJK HanSE LeeM ZhangX LuN Amin et al.

EPOS2020 : development strategy and goals for the latest European Position Paper on Rhinosinusitis

Wytske FokkensMartin DesrosiersRichard HarveyClaire HopkinsJoaquim MullolCarl PhilpottIsam AlobidWilma Terezinha Anselmo-LimaClaus BachertFuad Baroody et al.

A1 Journal Article in RHINOLOGY

EUFOREA consensus on biologics for CRSwNP with or without asthma

Wytske J FokkensValerie LundClaus BachertJoaquim MullolLeif BjermerJean BousquetGiorgio W CanonicaLauren DeneyerMartin DesrosiersZuzana Diamant et al.

A1 Journal Article in ALLERGY

Efficacy and safety of dupilumab in patients with chronic rhinosinusitis with nasal polyps : results from the randomized phase 3 sinus-24 study

Joseph K HanClaus BachertMartin DesrosiersTanya M LaidlawClaire HopkinsWytske J FokkensPierluigi PaggiaroSeong Ho ChoHeidi OlzeLeon S Greos et al.

Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52) : results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials

Claus BachertJoseph K HanMartin DesrosiersPeter W HellingsNikhil AminStella E LeeJoaquim MullolLeon S GreosJohn V BossoTanya M Laidlaw et al.

A1 Journal Article in LANCET

Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52) : results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials (vol 394, pg 1638, 2019)

Claus BachertJ. K. HanM. Desrosiers

Elevated IgE M1 prime transcripts in nasal tissues in patients with nasal polyps and asthma

Heleen ScheerensAshley SmithOlga LiLee HonigbergJeffrey M HarrisGabriële HoltappelsClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Endoscopic sinus surgery for type‐2 CRS wNP : an endotype‐based retrospective study

Saeed AlsharifKarin JonstamThibaut Van ZelePhilippe GevaertGabriële HoltappelsClaus Bachert

A1 Journal Article in LARYNGOSCOPE

Expansion of the role and functional characterization of a missense variant in CEP78 associated with cone-rod dystrophy and hearing loss

Giulia AscariFrank PeelmanPietro FarinelliToon RosseelNina LambrechtsIrina BalikovaLara DeryckeGabriële HoltappelsOlga KryskoThalia Van Laethem et al.

Expansion of the role and functional characterization of a missense variant in CEP78 associated with cone-rod dystrophy and hearing loss

Giulia AscariFrank PeelmanNina LambrechtsThalia Van LaethemToon RosseelPietro FarinelliDavid CreytensIrina BalikovaJan GerrisClaus Bachert et al.

From ARIA guidelines to the digital transformation of health in rhinitis and asthma multimorbidity

Jean BousquetJosep M AntoClaus BachertSinthia Bosnic-AnticevichMarina ErholaTari HaahtelaPeter HellingsPiotr KunaOliver PfaarBoleslaw Samolinski et al.

Editorial material

Guidance to 2018 good practice : ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma

J BousquetA BedbrookW CzarlewskiGL OnoratoS ArnavielheD LauneE Mathieu-DupasJ FonsecaE CostaO Lourenco et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

IFN-λ1 enhances Staphylococcus aureus clearance in healthy nasal mucosa but not in nasal polyps

Feng LanHua ZhongNan ZhangSebastian L JohnstonWeiping WenNikos PapadopoulosLuo ZhangClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IgE-mediated multimorbidities in allergic asthma and the potential for omalizumab therapy

Marc HumbertJean BousquetClaus BachertOscar PalomaresPascal PfisterIoannis KottakisXavier JaumontSimon Francis ThomsenNikolaos G Papadopoulos

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Immunogenic cell death induced by a new photodynamic therapy based on photosens and photodithazine

Victoria D TurubanovaIrina V BalalaevaTatiana A MishchenkoElena CatanzaroRazan AlzeibakNina N PeskovaIuliia EfimovaClaus BachertElena V MitroshinaOlga Krysko et al.

A1 Journal Article in JOURNAL FOR IMMUNOTHERAPY OF CANCER

Immunologic mechanisms of a short-course of Lolium perenne peptide immunotherapy : a randomized, double-blind, placebo-controlled trial

Hanisah SharifIesha SinghLubna KouserRalph MösgesMarie-Alix BonnyAngeliki KaramaniRebecca V ParkinNicolas BovyUday KishoreAbigail Robb et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Immunomodulatory properties of lolium perenne peptides for the treatment of seasonal allergic rhinitis

JA LayhadiH SharifI SinghA RobbL KouserR ParkinU SahinerA EifanM Penagos PaniaguaG Vila-Nadal et al.

Keratinocyte expression of A20/TNFAIP3 controls skin inflammation associated with atopic dermatitis and psoriasis

Michael DevosDenis A MogilenkoSébastien FleuryBarbara GilbertCoralie BecquartSandrine QuemenerHélène DehondtPeter TougaardBart StaelsClaus Bachert et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Medical algorithm : diagnosis and treatment of chronic rhinosinusitis

Claus BachertNan Zhang

Editorial material

Medication use in patients with chronic rhinosinusitis in Germany : a large retrospective patient-based study

Jonas Jae-Hyun ParkDavid Ulrich SeidelClaus BachertStefan DazertKarel Kostev

A1 Journal Article in RHINOLOGY

Mobile technology in allergic rhinitis : evolution in management or revolution in health and care?

Jean BousquetIgnacio J AnsoteguiJosep M AntoSylvie ArnavielheClaus BachertXavier BasagañaAnnabelle BédardAnna BedbrookMatteo BoniniSinthia Bosnic-Anticevich et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Mobile technology offers novel insights into the control and treatment of allergic rhinitis : the MASK study

Annabelle BédardXavier BasagañaJosep M AntoJudith Garcia-AymerichPhilippe DevillierSylvie ArnavielheAnna BedbrookGabrielle L OnoratoWienczyslawa CzarlewskiRuth Murray et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Nasal polyps and future risk of head and neck cancer : a nationwide population-based cohort study

Hyun Jung KimHyeong Sik AhnTaeuk KangClaus BachertWoo-Jung Song

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Next-generation ARIA care pathways for rhinitis and asthma : a model for multimorbid chronic diseases

J Jean BousquetHolger J SchunemannAlkis TogiasMarina ErholaPeter W HellingsTorsten ZuberbierIoana AgacheIgnacio J AnsoteguiJosep M AntoClaus Bachert et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Next-generation care pathways for allergic rhinitis and asthma multimorbidity : a model for multimorbid non-communicable diseases : meeting report (part 1)

Jean BousquetNhan Pham-ThiAnna BedbrookIoana AgacheIsabella Annesi-MaesanoIgnacio AnsoteguiJosep M AntoClaus BachertSamuel BenvenisteMike Bewick et al.

A1 Journal Article in JOURNAL OF THORACIC DISEASE

Next-generation care pathways for allergic rhinitis and asthma multimorbidity : a model for multimorbid non-communicable diseases : meeting report (part 2)

Jean BousquetNhan Pham-ThiAnna BedbrookIoana AgacheIsabella Annesi-MaesanoIgnacio AnsoteguiJosep M AntoClaus BachertSamuel BenvenisteMike Bewick et al.

A1 Journal Article in JOURNAL OF THORACIC DISEASE

Nonatopic severe asthma might still be atopic : sensitization toward Staphylococcus aureus enterotoxins

Jens SchreiberBarbara M. BrökerRainer EhmannClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Omalizumab efficacy and safety in nasal polyposis : results from two parallel, double-blind, placebo-controlled trials

Philippe GevaertClaus BachertJ. CorrenJ. MullolJ. HanR. OwL. IslamM. HowardR. OwenK. Wong et al.

Patient advisory board for chronic rhinosinusitis : a EUFOREA initiative

B PuginL DeneyerClaus BachertI AlobidJ BousquetG De CarloWJ FokkensS GaneC HopkinsC Holzmeister et al.

A1 Journal Article in RHINOLOGY

Protease/antiprotease network in allergy : the role of Staphylococcus aureus protease-like proteins

Olga KryskoAndrea Renate TeufelbergerSharon Van NevelDmitri KryskoClaus Bachert

A1 Journal Article in ALLERGY

Protein crystallization promotes type 2 immunity and is reversible by antibody treatment

Emma PerssonKenneth VerstraeteInes HeyndrickxElien GevaertHelena Catharine AegerterJean-Michel PercierKim DeswarteKoen VerschuerenAnn DansercoerDelphine Gras et al.

A1 Journal Article in SCIENCE

Real-life assessment of chronic rhinosinusitis patients using mobile technology

SF SeysS De BontJ BousquetClaus BachertWJ FokkensI AgacheM Bernal-SprekelsenI CallebautL CardellS Carrie et al.

Real-world benefits of allergen immunotherapy for birch pollen-associated allergic rhinitis and asthma

Ulrich WahnClaus BachertJoachim HeinrichHartmut RichterStefan Zielen

A1 Journal Article in ALLERGY

Reporting clinical trial results of phytomedicines in acute rhinosinusitis : letter to the Editor regarding Gottschlich S, Röschmann K, Candler H. Adv Ther (2018); 35:1023-1034. doi: 10.1007/s12325-018-0736-7

Claus BachertMayank ThakurSimon WeyersClaudia BittnerDimitri Abramov-Sommariva

A1 Journal Article in ADVANCES IN THERAPY

Rhinology future trends : 2017 EUFOREA debate on allergic rhinitis

Glenis ScaddingJean BousquetClaus BachertWytske J FokkensPeter HellingsEmmanuel ProkopakisOliver PfaarDavid Price

A1 Journal Article in RHINOLOGY

Sensitisation to staphylococcal enterotoxins and asthma severity : a longitudinal study in the EGEA cohort

Ina SintobinValerie SirouxGabriële HoltappelsChristophe PisonRachel NadifJean BousquetClaus Bachert

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Staphylococcus aureus nasal colonization and asthma in adults : systematic review and meta-analysis

Young-Chan KimHa-Kyeong WonJi Won LeeKyoung-Hee SohnMin-Hye KimTae-Bum KimYoon-Seok ChangByung-Jae LeeSang-Heon ChoClaus Bachert et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Staphylococcus aureus orchestrates type 2 airway diseases

Andrea Renate TeufelbergerBarbara M. BrökerDmitri KryskoClaus BachertOlga Krysko

A1 Journal Article in TRENDS IN MOLECULAR MEDICINE

Stepwise approach towards adoption of allergen immunotherapy for allergic rhinitis and asthma patients in daily practice in Belgium : a BelSACI-Abeforcal-EUFOREA statement

PW HellingsB PuginG MariënClaus BachertC BreynaertDM BullensJL CeuppensG ClementT CoxD Ebo et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma

Oliver PfaarClaus BachertPiotr KunaPetr PanznerMária DžupinováLudger KlimekMaroesja J van NimwegenJohan D BootDonghui YuDirk Jan E Opstelten et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Subsetting reveals CD16 high CD62L dim neutrophils in chronic rhinosinusitis with nasal polyps

Julia ArebroCecilia DrakskogOla WinqvistClaus BachertSusanna Kumlien GeorénLars‐Olaf Cardell

A1 Journal Article in ALLERGY

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps

Y ZhangLara DeryckeGabriële HoltappelsXD WangL ZhangClaus BachertNan Zhang

A1 Journal Article in ALLERGY

The GALEN rhinosinusitis cohort : chronic rhinosinusitis with nasal polyps affects health-related quality of life

Asif Hameed KhanThi Minh Thao HuynhGriet VandeplasVijay N JoishLeda P MannentPeter TomassenThibaut Van ZeleLars-Olaf CardellJulia ArebroHeidi Olze et al.

A1 Journal Article in RHINOLOGY

The Global Allergy and Asthma European Network (GALEN) rhinosinusitis cohort : a large European cross-sectional study of chronic rhinosinusitis patients with and without nasal polyps

Asif Hameed KhanGriet VandeplasThi Minh Thao HuynhVijay N. JoishLeda MannentPeter TomassenThibaut Van ZeleLars-Olaf CardellJulia ArebroHeidi Olze et al.

A1 Journal Article in RHINOLOGY

The effect of fine particulate matter on the inflammatory responses in human upper airway mucosa

Hui QingXiangdong WangNan ZhangKaili ZhengKun DuMing ZhengYing LiYu ChangLuo ZhangClaus Bachert

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Twelve-year follow-up study after endoscopic sinus surgery in patients with chronic rhinosinusitis with nasal polyposis

Lien CalusNicholas Van BruaeneCédric BosteelsSarah DejonckheereThibaut Van ZeleGabriële HoltappelsClaus BachertPhilippe Gevaert

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

2018

AIT has long‐term benefits for patients with allergic rhinitis and/or asthma induced by birch family pollen : refinement of real‐world study methodology designed to increase robustness of findings

U WahnClaus BachertJ HeinrichH RichterS Zielen

AIT is associated with reduced risk of asthma medication initiation and evolution up to 6 years after stopping AIT in patients with birch family pollen‐induced allergic rhinitis and/or asthma

S ZielenU WahnClaus BachertH RichterJ Heinrich

ARIA 2016 executive summary : integrated care pathways for predictive, preventive and personalized medicine across the life cycle

T ToJ BouchardLP BouletJ BrozekJ DenburgH SchünemannFER SimonsS WasermanPK KeithI Agache et al.

A2 Journal Article in CANADIAN JOURNAL OF RESPIRATORY CRITICAL CARE AND SLEEP MEDICINE

Activation of activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps

Lotta TengrothJulia ArebroOlivia LarssonClaus BachertSusanna Kumlien GeorénLars-Olaf Cardell

A1 Journal Article in SCIENTIFIC REPORTS

Allergy immunotherapy provides long‐term relief of birch family pollen‐induced allergic rhinitis up to 6 years following treatment cessation : a real‐world dataset analysis

Claus BachertU WahnJ HeinrichH RichterS Zielen

Atopic comorbidities and biomarkers of type 2 inflammation in patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) who failed intranasal corticosteroids

Claus BachertPeter W HellingsJoaquim MullolRobert M NaclerioDaniel L HamilosPhilippe GevaertDongui ZhangAsif KhanChunpeng FanNikhil Amin et al.

Chronic rhinosinusitis with nasal polyps is characterized by dysbacteriosis of the nasal microbiota

Thanit ChalermwatanachaiRamiro Vilchez VargasGabriële HoltappelsTim LacoereRuy JaureguiFrederiek-Maarten KerckhofDietmar H PieperTom Van de WieleMario VaneechoutteThibaut Van Zele et al.

A1 Journal Article in SCIENTIFIC REPORTS

Contribution of repeated infections in asthma persistence from preschool to school age : design and characteristics of the PreDicta cohort

Paraskevi XepapadakiClaus BachertSusetta FinottoTuomas JarttiGeorge N KonstantinouAlexander KieferMarek KowalskiAnna Lewandowska-PolakHeikki LukkarinenEirini Roumpedaki et al.

A1 Journal Article in PEDIATRIC ALLERGY AND IMMUNOLOGY

Current healthcare pathways in the treatment of rhinosinusitis in Germany

Jonas Jae-Hyun ParkClaus BachertStefan DazertKarel KostevDavid Ulrich Seidel

A1 Journal Article in ACTA OTO-LARYNGOLOGICA

Daily allergic multimorbidity in rhinitis using mobile technology : a novel concept of the MASK study

J BousquetP DevillierJM AntoM BewickT HaahtelaS ArnavielheA BedbrookR MurrayM van EerdJA Fonseca et al.

A1 Journal Article in ALLERGY

Development and characterization of effective DNAzymes against human rhinoviruses

DP PotaczekSD UngerNan ZhangS TakaS MichelN AkdagFeng LanM HelferC HudemannM Eickmann et al.

Dietary intake of flavonoids and ventilatory function in European adults : a GA2LEN study

Vanessa Garcia-LarsenNarjis ThawerDavid CharlesAedin CassidyThibaut Van ZeleTrine ThilsingMatti AhlströmTari HaahtelaThomas KeilPaolo Matricardi et al.

A1 Journal Article in NUTRIENTS

Dietary patterns and respiratory health in adults from nine European countries : evidence from the GA²LEN study

Ioannis BakolisRichard HooperClaus BachertBibi LangeTari HaahtelaThomas KeilStephanie HofmaierWytske FokkensBarbara RymarczykChrister Janson et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Dupilumab improves ACQ-5 items in CRSwNP patients with comorbid asthma

Peter HellingsClaus BachertJ MullolD HamilosR NaclerioL MannentN AminC TaniouG PirozziN. Graham et al.

Dupilumab improves mental health measures in patients with chronic rhinosinusitis and nasal polyposis (CRSwNP)

Claus BachertRobert NaclerioPeter HellingsSophie GuillonneauChristine TaniouJaman MaroniPaul RoweLeda MannentNikhil AminSiddesh Kamat et al.

Dupilumab reduces percentage volume of sinuses occupied by disease in patients with CRSwNP

Claus BachertJ ZinreichQ DongC FanD ZhangN AminL Mannent

EAACI guidelines on allergen immunotherapy : executive statement

A MuraroG RobertsS HalkenA AgacheL AngierM Fernandez-RivasR Gerth van WijkM JutelS LauG Pajno et al.

Editorial material

Ectopic lymphoid tissues support local immunoglobulin production in patients with chronic rhinosinusitis with nasal polyps

Jia SongHai WangYa-Na ZhangPing-Ping CaoBo LiaoZhe-Zheng WangLi-Li ShiYin YaoGuan-Ting ZhaiZhi-Chao Wang et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Electronic clinical decision support system for allergic rhinitis management: MASK e-CDSS

Anne-Lise CourbisRuth Brigid MurraySylvie ArnavielheDavide CaimmiAnna BedbrookMichiel Van EerdGovert De VriesGerard DrayIoana AgacheMario Morais-Almeida et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Endotype-driven approach for chronic rhinosinusitis

Claus BachertPeter Tomassen

Bookchapter in Implementing precision medicine in best practices of chronic airway diseases

Endotype-driven care pathways in patients with chronic rhinosinusitis

Claus BachertNan ZhangPeter W HellingsJean Bousquet

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

FcεRI expression and IgE binding by dendritic cells and basophils in allergic rhinitis and upon allergen immunotherapy

Margot BeringsPhilippe GevaertNatalie De RuyckLara DeryckeGabriële HoltappelsC PiletteClaus BachertBart LambrechtMelissa Dullaers

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Geolocation with respect to personal privacy for the Allergy Diary app : a MASK study

D SamrethS ArnavielheF IngenriethA BedbrookGL OnoratoR MurrayR AlmeidaMA MizaniJ FonsecaE Costa et al.

A1 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

Highlights of eosinophilic chronic rhinosinusitis with nasal polyps in definition, prognosis, and advancement

Hongfei LouNan ZhangClaus BachertLuo Zhang

A1 Journal Article in INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY

Immunomodulatory effect of Bifidobacterium breve on experimental allergic rhinitis in BALB/c mice

Jianjun RenYu ZhaoShi HuangDan LvFengling YangLin LouYongbo ZhengJie ZhangShixi LiuNan Zhang et al.

A1 Journal Article in EXPERIMENTAL AND THERAPEUTIC MEDICINE

Impact of chronic rhinosinusitis with nasal polyposis on quality of life by sino-nasal surgery history

Asif Hameed KhanT HuynhS KamatL MannentPeter TomassenThibaut Van ZeleLars-Olaf CardellJ ArebroH OlzeU Foerster-Ruhrmann et al.

In chronic spontaneous urticaria, IgE against staphylococcal enterotoxins is common and functional

S AltrichterT HawroM LiedtkeGabriële HoltappelsClaus BachertPS SkovM Maurer

A1 Journal Article in ALLERGY

Innate lymphoid cells in the upper airways : importance of CD117 and IL-1RI expression

Koen Van CrombruggenSylvie TaveirneGabriële HoltappelsGeorges LeclercqClaus Bachert

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Local IgE in subjects with allergic and non‐allergic rhinitis (LISA)

J HinkelJ EckrichA FischlE HerrmannGabriële HoltappelsClaus BachertS Zielen

Lolium perenne peptides for treatment of grass pollen allergy : a randomized, double-blind, placebo-controlled clinical trial

Mohamed H ShamjiJan CeuppensClaus BachertPeter HellingsGaël PlacierGaëtan ThirionNicolas BovyStephen R DurhamJean DuchateauThierry Legon et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

MASK 2017 : ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence

J BousquetS ArnavielheA BedbrookM BewickD LauneE Mathieu-DupasR MurrayGL OnoratoJL PépinR Picard et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Multivariate analysis of inflammatory endotypes in recurrent nasal polyposis in a Chinese population

Bo WeiFeng LiuJie ZhangYafeng LiuJintao DuShixi LiuNan ZhangClaus BachertJuan Meng

A1 Journal Article in RHINOLOGY

Prospective study on the outcome of the sphenoid drill out procedure

Thibaut Van ZeleBauke PauwelsFrank DewaelePhilippe GevaertClaus Bachert

A1 Journal Article in RHINOLOGY

Rapid onset of action and reduced nasal hyperreactivity : new targets in allergic rhinitis management

Claus BachertJ BousquetP Hellings

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Rhinology future debates 2017 by EUFOREA : novel treatments and surgical solutions in rhinology

Wytske J FokkensBenoit PuginClaus BachertJean BousquetGuy JoosRenaud LouisCharles PiletteOliver PfaarDavid PriceEmmanuel Prokopakis et al.

Editorial material

Rhinovirus species-specific antibodies differentially reflect clinical outcomes in health and asthma

Spyridon MegremisKatarzyna NiespodzianaClarissa CabauatanParaskevi XepapadakiMarek L KowalskiTuomas JarttiClaus BachertSusetta FinottoPeter WestSofia Stamataki et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Risk factors for post-9/11 chronic rhinosinusitis in Fire Department of the City of New York workers

Barbara PutmanRachel Zeig-OwensAnkura SinghCharles B HallTheresa SchwartzMayris P WebberHillel W CohenDavid J PrezantClaus BachertMichael D Weiden

A1 Journal Article in OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Short course of grass allergen peptides immunotherapy over 3 weeks reduces seasonal symptoms in allergic rhinoconjunctivitis with/without asthma : a randomized, multicenter, double-blind, placebo-controlled trial

R MösgesClaus BachertP PanznerMA CalderonL HaazenS PirottonN WatheletSR DurhamM-A BonnyT Legon et al.

A1 Journal Article in ALLERGY

Specific allergy and asthma prevention coming to an age : a milestone in children

Claus BachertCezmi A Akdis

Editorial material

Staphylococcus aureus controls interleukin-5 release in upper airway inflammation

Claus BachertGabriële HoltappelsMaia MerabishviliT MeyerA MurrNan ZhangKoen Van CrombruggenElien GevaertU VölkerBM Bröker et al.

A1 Journal Article in JOURNAL OF PROTEOMICS

Staphylococcus aureus enhances the tight junction barrier integrity in healthy nasal tissue, but not in nasal polyps

Can AltunbulakliRita CostaFeng LanNan ZhangMubeccel AkdisClaus BachertCezmi A Akdis

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Staphylococcus aureus induces a mucosal type 2 immune response via epithelial cell-derived cytokines

Feng LanNan ZhangGabriële HoltappelsNatalie De RuyckOlga KryskoKoen Van CrombruggenHarald BraunSebastian L JohnstonNikos G PapadopoulosLuo Zhang et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Th17 response against mucosal infection in persistent upper airways is partially impaired in viruses and bacteria coinfection condition

F LanL ZhangNan ZhangClaus Bachert

The Allergic Rhinitis and its Impact on Asthma (ARIA) score of allergic rhinitis using mobile technology correlates with quality of life : the MASK study

J BousquetS ArnavielheA BedbrookJ FonsecaM Morais AlmeidaA Todo BomI Annesi-MaesanoD CaimmiP DemolyP Devillier et al.

A1 Journal Article in ALLERGY

The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D

Andrea Renate TeufelbergerMaria NordengrünHarald BraunTania MaesKatrien De GroveGabriële HoltappelsClara O'BrienSharen ProvoostHamida HammadAmanda Gonçalves et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The airway microbiota : association with inflammatory patterns in chronic rhinosinusits

Thanit ChalermwatanachaiClaus BachertThibaut Van Zele

Transfer of innovation on allergic rhinitis and asthma multimorbidity in the elderly (MACVIA-ARIA) - EIP on AHA Twinning Reference Site (GARD research demonstration project)

J BousquetI AgacheMR AlibertiR AnglesI Annesi-MaesanoJM AntoS ArnavielheE AsayagE BacciA Bedbrook et al.

A1 Journal Article in ALLERGY

Treatment of allergic rhinitis using mobile technology with real world data : the MASK observational pilot study

J BousquetS ArnavielheA BedbrookG Alexis-AlexandreM van EerdR MurrayGW CanonicaM IllarioE MendittoG Passalacqua et al.

A1 Journal Article in ALLERGY

mySinusitisCoach : patient empowerment in chronic rhinosinusitis using mobile technology

S. F. SeysJ. BousquetClaus BachertW. J. FokkensI AgacheM. Bernal-SprekelsenI CallebautL. O. CardelS. CarrieP. Castelnuovo et al.

A1 Journal Article in RHINOLOGY

Η αλλεργική ρινίτιδα και η επίδρασή της στο άσθμα (ARIA) στην Ελλάδα Σχέδιο ολοκληρωμένης φροντίδας για την εφαρμογή προγνωστικής Ιατρικής καθ’ όλη τη διάρκεια της ζωής

N. G. PapadopoulosM. DimouT. VontetsianosP. GiallourosM. GagaV DanielidisN. DouladirisM. MakrisN. MikosP. Marangoudakis et al.

A2 Journal Article in ARCHIVES OF HELLENIC MEDICINE

2017

Advances and highlights in allergen immunotherapy: On the way to sustained clinical and immunologic tolerance

Margot BeringsCagatay KaraaslanCan AltunbulakliPhilippe GevaertMübeccel AkdisClaus BachertCezmi A Akdis

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Alcohol hyper-responsiveness in chronic rhinosinusitis with nasal polyps

Els De SchryverLara DeryckePaloma CampoEline GabrielsGuy JoosThibaut Van ZeleClaus BachertPeter W HellingsPhilippe Gevaert

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Allergic rhinitis and its impact on asthma (ARIA) guidelines : 2016 revision

Jan L BrożekJean BousquetIoana AgacheArnav AgarwalClaus BachertSinthia Bosnic-AnticevichRomina Brignardello-PetersenG Walter CanonicaThomas CasaleNiels H Chavannes et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Assessment of efficacy and safety of the herbal medicinal product BNO 1016 in chronic rhinosinusitis

J PalmI SteinerD Abramov-SommarivaA AmmendolaS MitzenheimH SteindlM WonnemannClaus Bachert

A1 Journal Article in RHINOLOGY

Biotherapeutics in chronic rhinosinusitis with and without nasal polyps

Claus BachertPhilippe GevaertPeter Hellings

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Building bridges for innovation in ageing : synergies between action groups of the EIP on AHA

J BousquetM BewickA CanoP EklundG FicoN GoswamiNA GuldemondD HendersonMJ HinkemaG Liotta et al.

A1 Journal Article in JOURNAL OF NUTRITION HEALTH & AGING

CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis : a SUNFRAIL report

J BousquetGL OnoratoClaus BachertM BarboliniA BedbrookL BjermerJ Correia de SousaNH ChavannesAA CruzE De Manuel Keenoy et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Characterization of human and Staphylococcus aureus proteins in respiratory mucosa by in vivo- and immunoproteomics

Frank SchmidtTanja MeyerNandakumar SundaramoorthyStephan MichalikKristin SurmannMaren DepkeVishnu DhopleManuela Gesell SalazarGabriële HoltappelsNan Zhang et al.

A1 Journal Article in JOURNAL OF PROTEOMICS

Chronic rhinosinusitis in Asia

Yuan ZhangElien GevaertHongfei LouXiangdong WangLuo ZhangClaus BachertNan Zhang

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dupilumab improves all ACQ-5 individual items in patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) and asthma : results from a phase 2a trial

Peter HellingsClaus BachertJoaquim MullolDaniel HamilosRobert NaclerioVijay JoishLeda MannentNikhil AminAdeline AbbeChristine Taniou et al.

Dupilumab improves sense of smell and reduces anosmia among patients with nasal polyposis and chronic sinusitis : results from a phase 2a trial

Robert M. NaclerioDaniel L. HamilosBerrylin J. FergusonClaus BachertPeter W. HellingsJoaquim MullolPhilippe GevaertDonghui ZhangAsif Hameed KhanChunpeng Fan et al.

Dust mite allergy in discussion : early diagnosis, better treatment

Eike WuestenbergLudger KlimekClaus BachertBoris HaxelEckard HamelmannOliver PfaarMartin WagenmannJoerg Kleine-Tebbe

A2 Journal Article in ALLERGO JOURNAL

EUFOREA Rhinology Research Forum 2016 : report of the brainstorming sessions on needs and priorities in rhinitis and rhinosinusitis

PW HellingsCA AkdisClaus BachertJ BousquetB PuginG AdriaensenR AdvaniI AgacheC AnjoR Anmolsingh et al.

A1 Journal Article in RHINOLOGY

European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases : report of the European Union Parliament Summit (29 March 2017)

Peter W HellingsDavid BorrelliSirpa PietikainenIoana AgacheCezmi AkdisClaus BachertMichael BewickErna BotjesJannis ConstantinidisWytske Fokkens et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Extent of sinus involvement in patients with bilateral nasal polyposis (NP) : baseline sinus ct scan results from a phase 2a study

Claus BachertS. J. ZinreichPeter HellingsJ. MullolD. L. HamilosPhilippe GevaertR. M. NaclerioN. AminV. N. JoishC. Fan et al.

Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in patients with severe airway inflammation

Elien GevaertNan ZhangOlga KryskoFeng LanGabriële HoltappelsNatalie De RuyckHans NauwynckShida YousefiHans-Uwe SimonClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Google Trends terms reporting rhinitis and related topics differ in European countries

Jean BousquetIoana AgacheJosep M AntoKarl C BergmannClaus BachertIsabella Annesi-MaesanoPhilippe J BousquetGennaro D'AmatoPascal DemolyGovert De Vries et al.

A1 Journal Article in ALLERGY

IL-21 is increased in nasal polyposis and after stimulation with Staphylococcus aureus enterotoxin B

Lien CalusLara DeryckeMelissa DullaersThibaut Van ZeleNatalie De RuyckClaudina Perez NovoGabriële HoltappelsGeert De VosBart LambrechtClaus Bachert et al.

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Is fruit and vegetable intake associated with asthma or chronic rhino-sinusitis in European adults? : results from the Global Allergy and Asthma Network of Excellence (GA²LEN) survey

Vanessa Garcia-LarsenRhonda ArthurJames F PottsPeter H HowarthMatti AhlströmTari HaahtelaCarlos LoureiroAna Todo BomGrzegorz BrożekJoanna Makowska et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Late-onset Inflammatory Airway Disease : from populations to endotypes

Peter TomassenClaus BachertThibaut Van Zele

Low concentration of uncouplers of oxidative phosphorylation decreases the TNF-induced endothelial permeability and lethality in mice

Vlada V ZakharovaOlga Yu PletjushkinaIvan I GalkinRoman A ZinovkinBoris V ChernyakDmitri KryskoClaus BachertOlga KryskoVladimir P SkulachevEkaterina N Popova

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mechanisms of the Development of Allergy (MeDALL) : introducing novel concepts in allergy phenotypes

Josep M AntoJean BousquetMubeccel AkdisCharles AuffrayThomas KeilIsabelle MomasDirkje S PostmaRudolf ValentaMagnus WickmanAnne Cambon-Thomsen et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Missense mutation in CEP78 in a family with cone-rod dystrophy, sensorineural hearing loss, obesity and subfertility

Giulia AscariStijn Van de SompeleLara DeryckeGabriële HoltappelsOlga KryskoJo Van DorpeDavid CreytensThalia Van LaethemIrina BalikovaJan Gerris et al.

Missense mutation in CEP78 in a family with cone-rod dystrophy, sensorineural hearing loss, obesity and subfertility.

Giulia AscariStijn Van de SompeleLara DeryckeGabriële HoltappelsOlga KryskoJo Van DorpeDavid CreytensThalia Van LaethemIrina BalikovaJan Gerris et al.

Multi-morbidities of allergic rhinitis in adults : European Academy of Allergy and Clinical Immunology Task Force report

C CingiPhilippe GevaertR MösgesC RondonV HoxM RudenkoNB MulukG ScaddingF ManoleC Hupin et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Nasal polyposis and asthma : a mechanistic paradigm focusing on Staphylococcus aureus

Claus BachertNan ZhangOlga KryskoKoen Van CrombruggenElien Gevaert

Bookchapter in The nose and sinuses in respiratory disorders

Necroptotic cell death in anti-cancer therapy

Olga KryskoTania Love AaesValerian E KaganKatharina D'HerdeClaus BachertLuc LeybaertPeter VandenabeeleDmitri Krysko

A1 Journal Article in IMMUNOLOGICAL REVIEWS

Non-allergic rhinitis : position paper of the European Academy of Allergy and Clinical Immunology

PW HellingsL KlimekC CingiI AgacheC AkdisClaus BachertJ BousquetP DemolyPhilippe GevaertV Hox et al.

A1 Journal Article in ALLERGY

Pilot study of mobile phone technology in allergic rhinitis in European countries : the MASK-rhinitis study

J BousquetDP CaimmiA BedbrookM BewickPW HellingsP DevillierS ArnavielheClaus BachertKC BergmannGW Canonica et al.

A1 Journal Article in ALLERGY

Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis : a EUFOREA-ARIA-EPOS-AIRWAYS ICP statement

PW HellingsWJ FokkensClaus BachertCA AkdisT BieberI AgacheM Bernal-SprekelsenGW CanonicaP GevaertGuy Joos et al.

A1 Journal Article in ALLERGY

Probiotics-impregnated bedding covers for house dust mite allergic rhinitis : a pilot randomized clinical trial

Margot BeringsAnton JultHanne VermeulenNatalie De RuyckLara DeryckeH UcarP GhekiereR TemmermanJ EllisClaus Bachert et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Probiotics-impregnated bedding covers in house dust mite allergic rhinitis patients : a double-blind, randomised, placebo-controlled, crossover clinical trial

Margot BeringsAnton JultHans VermeulenNatalie De RuyckLara DeryckeH. UcarP. GhekiereR. TemmermanJ. EllisClaus Bachert et al.

Programmed cell death-1 expression correlates with disease severity and IL-5 in chronic rhinosinusitis with nasal polyps

I Kortekaas KrohnS BobicJ DooleyFeng LanNan ZhangClaus BachertB SteelantDM BullensA ListonJL Ceuppens et al.

A1 Journal Article in ALLERGY

Prospective open-label evaluation of long-term low-dose doxycycline for difficult-to-treat chronic rhinosinusitis with nasal polyps

Ana Carolina Pinto Bezerra SoterThiago Freire BezerraRogerio PezatoTatiana Regina Teles AbdoRenata Mendonca PilanFabio de Rezende PinnaPhilippe GevaertThibaut Van ZeleClaus BachertRichard Louis Voegels

A1 Journal Article in RHINOLOGY

Reduced need for surgery in severe nasal polyposis with mepolizumab : randomized trial

Claus BachertAna R SousaValerie J LundGlenis K ScaddingPhilippe GevaertShuaib NasserStephen R DurhamMarjolein E CornetHarsha H KariyawasamJane Gilbert et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Reliable mite-specific IgE testing in nasal secretions by means of allergen microarray

Margot BeringsStefania ArasiNatalie De RuyckSerena PernaYvonne ReschChristian LupinekKuan-Wei ChenSusanne VrtalaGiovanni Battista PajnoClaus Bachert et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rhinology future debates, an EUFOREA report

Wytske J FokkensClaus BachertManuel Bernal-SprekelsenJean BousquetMichel DjandjiAlejandro DorenbaumDorna Hakim-MehrStuart HendryClaire HopkinsAndreas Leunig et al.

A1 Journal Article in RHINOLOGY

Sensitization patterns and minimum screening panels for aeroallergens in self-reported allergic rhinitis in China

Hongfei LouSiyuan MaYan ZhaoFeifei CaoFei HeZhongyan LiuJean BousquetChengshuo WangLuo ZhangClaus Bachert

A1 Journal Article in SCIENTIFIC REPORTS

Serum periostin, IgE, and SE-IgE can be used as biomarkers to identify moderate to severe chronic rhinosinusitis with nasal polyps

Karin JonstamMarit WestmanGabriële HoltappelsCecile TJ HolwegClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus

Sebastian StentzelAndrea Renate TeufelbergerMaria NordengrünJulia KolataFrank SchmidtKoen Van CrombruggenStephan MichalikJana KumpfmüllerSebastian TischerThomas Schweder et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Staphylococcus aureus enterotoxin sensitization is associated with allergic poly-sensitization and allergic multimorbidity in adolescents

M SørensenC KlingenbergM WickmanJUE SollidA-S FurbergClaus BachertJ Bousquet

A1 Journal Article in ALLERGY

Suppression of allergen-induced basophil activation upon treatment with subcutaneous house dust mite immunotherapy: a prospective study

Margot BeringsNatalie De RuyckLara DeryckeGabriële HoltappelsClaus BachertBart LambrechtMelissa DullaersPhilippe Gevaert

The IL-33/ST2 axis is crucial in type 2 airway responses induced by the Staphylococcus aureus protease SpID

Olga KryskoAndrea Renate TeufelbergerMaria NordengrunTania MaesBarbara BrokerClaus Bachert

The effect of systemic treatments on periostin expression reflects their interference with the eosinophilic inflammation in chronic rhinosinusitis with nasal polyps

Emile De SchryverLara DeryckeLien CalusGabriële HoltappelsPeter HellingsThibaut Van ZeleClaus BachertPhilippe Gevaert

A1 Journal Article in RHINOLOGY

Validation of the Global Allergy and Asthma European Network (GA2LEN) chamber for trials in allergy : innovation of a mobile allergen exposure chamber

Torsten ZuberbierMark B AbelsonCezmi A AkdisClaus BachertUwe BergerCarsten Bindslev-JensenGeorg BoelkeJean BousquetGiorgio Walter CanonicaThomas B Casale et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Work productivity in rhinitis using cell phones : the MASK pilot study

J BousquetM BewickS ArnavielheE Mathieu-DupasR MurrayA BedbrookDP CaimmiO VandenplasPW HellingsClaus Bachert et al.

A1 Journal Article in ALLERGY

2016

A randomized, 5-arm dose finding study with a mite allergoid SCIT in allergic rhinoconjunctivitis patients

O PfaarMJ NellJD BootSA VersteegR van ReeA RogerH RiechelmannA SperlJNG Oude ElberinkZ Diamant et al.

A1 Journal Article in ALLERGY

ARIA 2016 : care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle

J BousquetPW HellingsI AgacheA BedbrookClaus BachertKC BergmannM BewickC Bindslev-JensenS Bosnic-AnticevitchC Bucca et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Advances in rhinitis and rhinosinusitis in 2015

Claus BachertElien Gevaert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergy immunotherapy across the life cycle to promote active and healthy ageing : from research to policies

MA CalderonP DemolyT CasaleCA AkdisClaus BachertM BewickBM BilòB BohleS BoniniA Bush et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

An increased prevalence of self-reported allergic rhinitis in major Chinese cities from 2005 to 2011

XD WangM ZhengHF LouCS WangY ZhangMY BoSQ GeNan ZhangL ZhangClaus Bachert

A1 Journal Article in ALLERGY

Barrier function of the nasal mucosa in health and type-2 biased airway diseases

Nan ZhangKoen Van CrombruggenElien GevaertClaus Bachert

A1 Journal Article in ALLERGY

Cellular phenotyping of chronic rhinosinusitis with nasal polyps

Hongfei LouYifan MengYingshi PiaoNan ZhangClaus BachertChengshuo WangLuo Zhang

A1 Journal Article in RHINOLOGY

Chronic rhinosinusitis patients show accumulation of genetic variants in PARS2

Viktor HenmyrChristina Lind-HalldénChrister HalldénTorbjörn SällDaniel CarlbergClaus BachertLars-Olaf Cardell

A1 Journal Article in PLOS ONE

Chronic rhinosinusitis phenotypes : an approach to better medical care for chronic rhinosinusitis

Seong H ChoClaus BachertRichard F Lockey

Editorial material

Cytokine profile of nasal and middle ear polyps in a patient with Woakes' syndrome and eosinophilic otitis media

MARIE DE LOOFEls De LeenheerGabriële HoltappelsClaus Bachert

A2 Journal Article in BMJ CASE REPORTS

Diversity of TH cytokine profiles in patients with chronic rhinosinusitis : a multicenter study in Europe, Asia, and Oceania

Xiangdong WangNan ZhangMingyu BoGabriële HoltappelsMing ZhengHongfei LouHong WangLuo ZhangClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dupilumab improves health-related quality of life and absenteeism in nasal polyposis patients : results from a phase 2a trial

Claus BachertP HellingsJ MullolD HamilosR NaclerioVN JoishL MannentR EvansA AbbeC. Amand et al.

Dupilumab improves patient-reported outcomes in chronic sinusitis with nasal polyps patients with comorbid asthma : results from a phase 2a trial

Claus BachertPeter HellingsJoaquim MullolDaniel HamilosRobert NaclerioVijay N JoishLeda MannentRobert E EvansAnnette GrabherAdeline Abbe et al.

Effect of subcutaneous dupilumab on nasal polyp burden in patients with chronic sinusitis and nasal polyposis : a randomized clinical trial

Claus BachertLeda MannentRobert M NaclerioJoaquim MullolBerrylin J FergusonPhilippe GevaertPeter HellingsLixia JiaoLin WangRobert R Evans et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Hypothesis : may e-cigarette smoking boost the allergic epidemic?

Jean BousquetClaus BachertLaura Crotty AlexanderFrank T Leone

Editorial material

Immunogenic apoptotic cell death and anticancer immunity

Peter VandenabeeleKatrien VandecasteeleClaus BachertOlga KryskoDmitri Krysko

A1 Journal Article in Advances in Experimental Medicine and Biology

Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers

Peter TomassenGriet VandeplasThibaut Van ZeleLars-Olaf CardellJulia ArebroHeidi OlzeUlrike Förster-RuhrmannMarek L KowalskiAgnieszka Olszewska-ZiąberGabriële Holtappels et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Innovative therapeutic targets in chronic sinusitis with nasal polyps

Editorial material

LTD4 and TGF-β1 induce the expression of metalloproteinase-1 in chronic rhinosinusitis via a cysteinyl leukotriene receptor 1-related mechanism

Rogerio PezatoCindy ClaeysGabriële HoltappelsClaus BachertClaudina Perez Novo

A2 Journal Article in SINUSITIS

Lovely image of a Tornwaldt's cyst

MARIE DE LOOFClaus Bachert

A1 Journal Article in INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY

MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis

Jean BousquetHolger J SchünemannPeter W HellingsSylvie ArnavielheClaus BachertAnna BedbrookKarl-Christian BergmannSinthia Bosnic-AnticevichJan BrozekMoises Calderon et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

MP-AzeFlu provides rapid and effective allergic rhinitis control in real life : a pan-European study

Ludger KlimekClaus BachertPar StjärneRalph DollnerPetter LarsenPeter HaahrIoana AgacheGlenis ScaddingDavid Price

A1 Journal Article in ALLERGY AND ASTHMA PROCEEDINGS

Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story Mechanisms of the Development of ALLergy; EUFP7-CP-IP; project no: 261357; 2010-2015

J BousquetJM AntoM AkdisC AuffrayT KeilI MomasDS PostmaR ValentaM WickmanA Cambon-Thomsen et al.

A1 Journal Article in ALLERGY

Phenotypes and emerging endotypes of chronic rhinosinusitis

Claus BachertCezmi A Akdis

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

Respiratory hypersensitivity reactions to NSAIDs in Europe : the global allergy and asthma network (GA2LEN) survey

JS MakowskaP BurneyD JarvisT KeilPeter TomassenJ BislimovskaG BrozekClaus BachertJ BaelumC Bindslev-Jensen et al.

A1 Journal Article in ALLERGY

Rupatadine : global safety evaluation in allergic rhinitis and urticaria

Vanesa González-NúñezClaus BachertJoaquim Mullol

A1 Journal Article in EXPERT OPINION ON DRUG SAFETY

Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)

J BousquetJ FarrellG CrooksP HellingsEH BelM BewickNH ChavannesJ Correia de SousaAA CruzT Haahtela et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

SplD- : a novel inhalant allergen from S. aureus causes Th2 bias in mice

Olga KryskoAndrea Renate TeufelbergerSebastian StentzelKatrien De GroveTania MaesGabriële HoltappelsBarbara BroekerClaus Bachert

Staphylococcal enterotoxin IgE sensitization in late-onset severe eosinophilic asthma in the elderly

W-J SongIna SintobinK-H SohnM-G KangE-J JoS-E LeeM-S YangH-K ParkYE KwonT-B Kim et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Systemic expression of inflammatory mediators in patients with chronic rhinosinusitis and nasal polyps with and without Aspirin Exacerbated Respiratory Disease

Rogerio PezatoMonika Świerczyńska-KrępaEwa Niżankowska-MogilnickaGabriële HoltappelsNatalie De RuyckMarek SanakLara DeryckeKoen Van CrombruggenClaus BachertClaudina Perez Novo

A1 Journal Article in CYTOKINE

Th2 biased upper airway inflammation is associated with an impaired response to viral infection with Herpes simplex virus 1

Feng LanXiang Dong WaneHans NauwynckGabriële HoltappelsLuo ZhangSebastian L JohnstonNikolaos G PapadopoulosClaus BachertNan Zhang

A1 Journal Article in RHINOLOGY

The protease SplD provides a link between asthma and mucosal S. aureus colonization

Andrea Renate TeufelbergerS StentzelHarald BraunTania MaesGabriële HoltappelsSharen ProvoostKatrien De GroveRudi BeyaertDmitri KryskoB Broeker et al.

The quest for autoreactive antibodies in nasal polyps

Els De SchryverLien CalusHenryk BonteNatalie De RuyckHannah GouldErin DonovanDirk ElewautRudolf ValentaIrene MittermannJan Gutermuth et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The response to nasal allergen provocation with grass pollen is reduced in patients with chronic rhinosinusitis with nasal polyposis and grass sensitization

Lien CalusLien DevuystThibaut Van ZeleNatalie De RuyckLara DeryckeClaus BachertPhilippe Gevaert

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

The role of viruses and Staphylococcus aureus in propagating a Th2 response in human nasal polyps

Feng LanClaus BachertNan Zhang

UK prescribing practices as proxy markers of unmet need in allergic rhinitis : a retrospective observational study

David B PriceGlenis ScaddingClaus BachertHesham SalehShuaib NasserVictoria CarterJulie von ZiegenweidtAlice MS DurieuxDermot Ryan

A1 Journal Article in NPJ PRIMARY CARE RESPIRATORY MEDICINE

Viruses and bacteria in Th2-biased allergic airway disease

F LanNan ZhangElien GevaertL ZhangClaus Bachert

A1 Journal Article in ALLERGY

2015

A chest physician's guide to mechanisms of sinonasal disease

V HoxTania MaesWouter HuvenneC Van DrunenJA VanoirbeekGuy JoosClaus BachertW FokkensJL CeuppensB Nemery et al.

A1 Journal Article in THORAX

A common language to assess allergic rhinitis control : results from a survey conducted during EAACI 2013 congress

Peter W HellingsAntonella MuraroWytske FokkensJoaquim MullolClaus BachertG Walter CanonicaDavid PriceNikos PapadopoulosGlenis ScaddingGerd Rasp et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Advances in pharmacotherapy for the treatment of allergic rhinitis; MP29-02 (a novel formulation of azelastine hydrochloride and fluticasone propionate in an advanced delivery system) fills the gaps

Jean BousquetClaus BachertJonathan BernsteinG Walter CanonicaWarner CarrRonald DahlPascal DemolyPhilippe DevillierPeter HellingsWytske Fokkens et al.

A1 Journal Article in EXPERT OPINION ON PHARMACOTHERAPY

Airway inflammation in chronic rhinosinusitis with nasal polyps and asthma: the united airways concept further supported

Kåre HåkanssonClaus BachertLars KongeSimon Francis ThomsenAnders Elm PedersenSteen Seier PoulsenTomas Martin-BertelsenOle WintherVibeke BackerChristian von Buchwald

A1 Journal Article in PLOS ONE

Allergen immunotherapy (AIT) : a prototype of precision medicine

GW CanonicaClaus BachertP HellingsD RyanE ValovirtaM WickmanO De BeaumontJ Bousquet

A1 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

Allergen immunotherapy on the way to product-based evaluation : a WAO statement

Claus BachertMark LarchéSergio BoniniGiorgio Walter CanonicaThomas KündigDesiree Larenas-LinnemannDennis LedfordHugo NeffenRuby PawankarGiovanni Passalacqua

A1 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme

Norbert KrugJens M HohlfeldAnne-Marie KirstenOliver KornmannKai M BeehDominik KappelerStephanie KornStanislav IgnatenkoWolfgang TimmerCordelia Rogon et al.

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE

Allergic sensitization, high local IL-5 and IgE predict surgical outcome 12 years after endoscopic sinus surgery for chronic rhinosinusitis with nasal polyposis

Philippe GevaertLien CalusNicholas Van BruaeneThibaut Van ZeleClaus Bachert

Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? : the MeDALL hypothesis

J BousquetJM AntoM WickmanT KeilR ValentaT HaahtelaK Lodrup CarlsenM van HageC AkdisClaus Bachert et al.

A1 Journal Article in ALLERGY

Association of mucosal organisms with patterns of inflammation in chronic rhinosinusitis

Thanit ChalermwatanachaiNan ZhangGabriële HoltappelsClaus Bachert

A1 Journal Article in PLOS ONE

Association of periostin expression with eosinophilic inflammation in nasal polyps

Min WangXiangdong WangNan ZhangHong WangYing LiErzhong FanLiang ZhangLuo ZhangClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Burden of rhinitis among European Academy of Allergy & Clinical Immunology (EAACI) members

J BousquetClaus BachertD PriceS AcasterN PapadopoulosA Muraro

Characterization of the in vivo immune network of IDO, tryptophan metabolism, PD-L1, and CTLA-4 in circulating immune cells in melanoma

Ines ChevoletReinhart SpeeckaertMax SchreuerB NeynsOlga KryskoClaus BachertB HennartD AllorgeNanja van GeelMireille Van Gele et al.

A1 Journal Article in ONCOIMMUNOLOGY

Clinical significance of plasmacytoid dendritic cells and myeloid-derived suppressor cells in melanoma

Ines ChevoletReinhart SpeeckaertMax SchreuerBart NeynsOlga KryskoClaus BachertMireille Van GeleNanja van GeelLieve Brochez

A1 Journal Article in JOURNAL OF TRANSLATIONAL MEDICINE

Comparison of different medical treatment options for CRSwNP : doxycycline, methylprednisolone, mepolizumab and omalizumab

Els De SchryverThibaut Van ZeleClaus BachertPhilippe Gevaert

Cost-effectiveness of immunotherapy in the treatment of seasonal allergic rhinitis : identifying product-specific parameters of relevance for health care decision-makers and clinicians

Claus BachertJakob Noergaard Andreasen

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Current and future treatment options for adult chronic rhinosinusitis: Focus on nasal polyposis

Claus BachertLuo ZhangPhilippe Gevaert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Current controversies and challenges in allergic rhinitis management

David PricePete SmithPeter HellingsNikos PapadopoulosWytske FokkensAntonella MuraroRuth MurrayAlison ChisholmPascal DemolyGlenis Scadding et al.

A1 Journal Article in EXPERT REVIEW OF CLINICAL IMMUNOLOGY

DNA methylation, bacteria and airway inflammation: latest insights

Claudina Perez NovoClaus Bachert

A1 Journal Article in CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY

Design of a phase III short-term efficacy study with allergen specific immunotherapy in patients with birch pollen induced allergic rhinitis/rhinoconjunctivitis

M van NimwegenO PfaarP KunaP PanznerM DzupinovaD BootClaus Bachert

Differential cytokine profiles upon comparing selective versus classic glucocorticoid receptor modulation in human peripheral blood mononuclear cells and inferior turbinate tissue

Ilse BeckKoen Van CrombruggenGabriële HoltappelsFrançois DaubeufNelly FrossardClaus BachertKarolien De Bosscher

A1 Journal Article in PLOS ONE

Differential expression and release of activin A and follistatin in chronic rhinosinusitis with and without nasal polyps

Yucheng YangNan ZhangKoen Van CrombruggenFeng LanGuohua HuSuling HongClaus Bachert

A1 Journal Article in PLOS ONE

Differential release and deposition of S100A8/A9 proteins in inflamed upper airway tissue

Koen Van CrombruggenThomas VoglClaudina Perez NovoGabriële HoltappelsClaus Bachert

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Dupilumab in chronic sinusitis with nasal polyposis, with and without asthma

Claus BachertL MannentRM NaclerioJ MullolBJ FergusonL JiaoL WangRR EvansG PirozziNM Graham et al.

Effect of budesonide transnasal nebulization in patients with eosinophilic chronic rhinosinusitis with nasal polyps

Chengshuo WangHongfei LouXiangdong WangYang WangErzhong FanYing LiHong WangClaus BachertLuo Zhang

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Effectiveness of MP29-02 for the treatment of allergic rhinitis in real-life: results from a noninterventional study

Ludger KlimekClaus BachertRalph MösgesUllrich MunzelDavid PriceJ Christian VirchowUlrich WahnJean Bousquet

A1 Journal Article in ALLERGY AND ASTHMA PROCEEDINGS

Effects of Bifidobacterium breve feeding strategy and delivery modes on experimental allergic rhinitis mice

Jian-Jun RenZhao YuFeng-Ling YangDan LvShi HungJie ZhangPing LinShi-Xi LiuNan ZhangClaus Bachert

A1 Journal Article in PLOS ONE

Emerging biologics for the treatment of chronic rhinosinusitis

Bauke PauwelsKarin JonstamClaus Bachert

A1 Journal Article in EXPERT REVIEW OF CLINICAL IMMUNOLOGY

Endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers

Peter TomassenClaus Bachert

Herbal drug BNO 1016 is safe and effective in the treatment of acute viral rhinosinusitis

Rainer JundMartin MondiglerHolger StammerPontus StiernaClaus Bachert

A1 Journal Article in ACTA OTO-LARYNGOLOGICA

Identification of gaps in the current allergic rhinitis guidelines and how these can be filled

J BousquetClaus BachertJ MullolD PriceW FokkensP HellingsN PapadopoulosM Antonella

Is immunoglobulin E to Staphylococcus aureus enterotoxins associated with asthma at 20 years?

Ina SintobinThomas KeilSusanne LauLinus GrabenhenrichGabriële HoltappelsAndreas ReichUlrich WahnClaus Bachert

A1 Journal Article in PEDIATRIC ALLERGY AND IMMUNOLOGY

Local immunoglobulin E in the nasal mucosa : clinical implications

Els De SchryverLien DevuystLara DeryckeMelissa DullaersThibaut Van ZeleClaus BachertPhilippe Gevaert

A1 Journal Article in ALLERGY ASTHMA & IMMUNOLOGY RESEARCH

MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation

J BousquetHJ SchunemannJ FonsecaB SamolinskiClaus BachertGW CanonicaT CasaleAA CruzP DemolyP Hellings et al.

A1 Journal Article in ALLERGY

MP29-02* provides a rapid clinically-meaningful response for moderate/severe seasonal allergic rhinitis patients : a meta-analysis

J MullolClaus BachertD PriceG ScaddingHC KuhlJ Bousquet

MP29-02* provides effective AR symptom control in real life in all patient types regardless of predominant nasal symptom or presence of ocular symptoms: results from Germany

Claus BachertR MösgesJC VirchowU WahnHC KuhlL Klimek

MP29-02* provides effective AR symptom control in real life in previous or potential treatment failure patients : results from Germany

JC VirchowL KlimekU WahnR MoesgesHC KuhlClaus Bachert

MP29-02* provides effective AR symptom control in real life regardless of number of previous clinic visits : results from Germany

U WahnClaus BachertJC VirchowR MoesgesHC KuhlL Klimek

MP29-02* provides effective relief in real life in all patients regardless of ARIA-defined severity : results from Germany

L KlimekJC VirchowU WahnR MoesgesH-C KuhlClaus Bachert

MP29-02* provides effective relief in real life in patients previously treated with mono- and multiple-therapy : results from Germany

L KlimekJC VirchowU WahnR MösgesH-C KuhlClaus Bachert

MP29-02*'s advanced delivery system contributes to its efficacy in patients with moderate/severe seasonal allergic rhinitis

Claus BachertGW CanonicaJ MullolD PriceP HellingsG ScaddingU MunzelJ Bousquet

Mite allergen-specific IgE is detectable in bronchial secretions of patients with non-atopic asthma and correlates with mucosal expression of periostin

Jonathan MouthuySophie ViartMaha Z LadjemiBruno DetryMonique HenketClaus BachertRenaud LouisCharles Pilette

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Nasal immunity, rhinitis, rhinosinustis

Claus BachertOlga KryskoPhilippe GevaertMargot BeringsClaudina Perez NovoKoen Van Crombruggen

Bookchapter in Mucosal immunology

Pathophysiologie der chronischen Rhinosinusitis, konservative Therapieoptionen

Claus BachertGabriële Holtappels

A1 Journal Article in LARYNGO-RHINO-OTOLOGIE

Pathophysiology of chronic rhinosinusitis, pharmaceutical therapy options

Claus BachertGabriële Holtappels

A2 Journal Article in GMS CURRENT TOPICS IN OTORHINOLARYNGOLOGY. HEAD AND NECK SURGERY

Predictive significance of tissue eosinophilia for nasal polyp recurrence in the Chinese population

Hongfei LouYifan MengYingshi PiaoChengshuo WangLuo ZhangClaus Bachert

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY & ALLERGY

Prevalence of allergic rhinitis among adults in urban and rural areas of China : a population-based cross-sectional survey

Ming ZhengXiangdong WangMingyu BoKuiji WangYan ZhaoFei HeFeifei CaoLuo ZhangClaus Bachert

A1 Journal Article in ALLERGY ASTHMA & IMMUNOLOGY RESEARCH

Severity of asthma symptoms, lung function and airway inflammation in the PreDicta cohort of preschool-age children with asthma

E RoumpedakiD KarantoumanisP XepapadakiIna SintobinClaus BachertH LukkarinenT JarttiT ZimmermanS FinottoA Sobanska et al.

Staphyloccoccus aureus induces a Th2 response via TSLP and IL-33 release in human airway mucosa

Feng LanNan ZhangGabriële HoltappelsNatalie De RuyckNikolaos G PapadopoulosSebastian L JohnstonClaus Bachert

Staphylococcus aureus enterotoxin B induces airway epithelial barrier dysfunction in vitro

B SteelantFeng LanNan ZhangS SeysI Kortekaas KrohnJL CeuppensClaus BachertC AkdisPW Hellings

TMEM16A-Mediated mucin secretion in IL-13-induced nasal epithelial cells from chronic rhinosinusitis patients

Yu ZhangXiangdong WangHong WangJian JiaoYing LiErzhong FanLuo ZhangClaus Bachert

A1 Journal Article in ALLERGY ASTHMA & IMMUNOLOGY RESEARCH

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in chronic rhinosinusitis with nasal polyps

Yu ZhangLara DeryckeLuo ZhangGabriële HoltappelsXiangdong WangNan ZhangClaus Bachert

The 'GA2LEN Sinusitis Cohort' : an introduction

Griet VandeplasAsif KhanThi Minh HuynhPeter TomassenThibaut Van ZeleLars-Olaf CardellJulia ArebroHeidi OlzeUlrike FoersterMarek Leszek Kowalski et al.

The GALEN sinusitis cohort : impact on quality of life in patients with chronic rhinosinusitis with nasal polyps (CRSwNP)

A KhanGriet VandeplasT HuynhL MannentPeter TomassenThibaut Van ZeleLars-Olaf CardellJ ArebroHeidi OlzeUlrike Foerster et al.

The clinical significance of the pollen calendar of the Western Thrace/northeast Greece region in allergic rhinitis

Michael KatotomichelakisChristos NikolaidisMichael MakrisNan ZhangXenophon AggelidesTheodoros C ConstantinidisClaus BachertVassilios Danielides

A1 Journal Article in INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY

The hidden burden of adult allergic rhinitis : UK healthcare resource utilisation survey

David PriceGlenis ScaddingDermot RyanClaus BachertG Walter CanonicaJoaquim MullolLudger KlimekRichard PitmanSarah AcasterRuth Murray et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

The microbiome of the upper airways : focus on chronic rhinosinusitis

Thanit ChalermwatanachaiLeydi VelasquezClaus Bachert

A1 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

The ‘GA^2LEN sinusitis cohort’ : an introduction

Griet VandeplasAsif Hameed KhanThi Minh Thao HuynhPeter TomassenThibaut Van ZeleLars-Olaf CardellJulia ArebroHeidi OlzeUlrike FoersterMarek Leszek Kowalski et al.

Three dimensional computed tomographic analysis of sinonasal air volume as an objective outcome measure for chronic rhinosinusitis with nasal polyps

B PauwelsF FerreiraW VosC Van HolsbekeJ De BackerLara DeryckeClaus Bachert

Update on rupatadine in the management of allergic disorders

J MullolJ BousquetClaus BachertGW CanonicaA Giménez-ArnauML KowalskiFER SimonsM MaurerD RyanG Scadding

A1 Journal Article in ALLERGY

Use of filter disks or sinus packs for single and repeated measurement of total and house dust mite specific IgE in nasal secretions

Margot BeringsNatalie De RuyckGabriële HoltappelsClaus BachertPhilippe Gevaert

2014

300IR 5-Grass pollen sublingual tablet offers relief from nasal symptoms in patients with allergic rhinitis

Elie SerranoHans Ulrich WahnAlain DidierClaus Bachert

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY & ALLERGY

A new intranasal therapy MP29-02* is more effective than current firstline therapy regardless of season, symptom or severity

Claus BachertD PriceW FokkensP HellingsU MunzelJ Bousquet

Advances in allergen-microarray technology for diagnosis and monitoring of allergy: the MeDALL allergen-chip

Christian LupinekEva WollmannAlexandra BaarSrinita BanerjeeHeimo BreitenederBarbara M BroeckerMerima BublinMirela CurinSabine FlickerTetiana Garmatiuk et al.

A1 Journal Article in METHODS

Assessing allergic rhinitis symptom control using a simple visual analogue scale: the digital solution

J BousquetClaus BachertD PriceS AcasterP Demoly

Atopy, rhinitis, lung function and inflammation in asthmatic preschoolers and healthy controls

E RoumpedakiP XepapadakiP TaprantziTineke DutréClaus BachertH LukkarinenT JarttiA GraserT ZimmermannS Finotto et al.

Cigarette smoke exposure alters the development of inflammation in experimental Crohn-like colitis

Liesbeth AllaisStephanie VerscheureKen BrackeRebecca De SmetDebby LaukensClaus BachertMartine De VosGuy BrusselleClaude Cuvelier

Clinical relevance is associated with allergen-specific wheal size in skin prick testing

T HaahtelaGJ BurbachClaus BachertC Bindslev-JensenS BoniniJ BousquetL Bousquet-RouanetPJ BousquetM BrescianiA Bruno et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Deposition characteristics of a new allergic rhinitis nasal spray (MP29-02*) in an anatomical model of the human nasal cavity

A D'AddioN RuizM MayerS DeClaus BachertJ Bousquet

Differences in initial immunoprofiles between recurrent and nonrecurrent chronic rhinosinusitis with nasal polyps

Thibaut Van ZeleGabriële HoltappelsPhilippe GevaertClaus Bachert

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY & ALLERGY

Different regulation of activin A and follistatin in chronic rhinosinusitis with or without nasal polyps

Y YangNan ZhangF LanKoen Van CrombruggenG HuS HongClaus Bachert

Dose finding study with a subcutaneous specific immunotherapy allergoid in patients with house dust mite induced allergic rhinitis/rhinoconjunctivitis

O PfaarMJ NellJD BootDJE OpsteltenSA VersteegR van ReeA RogerH RiechelmannJNGO ElberinkClaus Bachert

Dynamics of treatment within a year in patients diagnosed with either allergic, non-allergic rhinitis or hay fever over the period 1992-2012

D PriceG ScaddingClaus BachertH SalehS NasserV CarterK BichelD Ryan

Efficacy and safety of immunotherapy in patients with different clinical characteristics

MJ NellO PfaarJD BootE van TwuijverP van OschClaus Bachert

Efficacy of 300IR 5-grass pollen sublingual tablets in the treatment of rhinitis symptoms in patients with grass pollen-induced allergic rhinoconjunctivitis

Claus BachertAlain DidierLaurence AmbroisineKathy AbiteboulRobert K Zeldin

Geographical variation in the prevalence of sensitization to common aeroallergens in adults: the GA²LEN survey

RB NewsonR van ReeB ForsbergC JansonJ LötvallS-E DahlénEM ToskalaJ BaelumGM BrożekL Kasper et al.

A1 Journal Article in ALLERGY

Guideline on allergen-specific immunotherapy in IgE-mediated allergic diseases

Oliver PfaarClaus BachertAlbrecht BufeRoland BuhlChristof EbnerPeter EngFrank FriedrichsThomas FuchsEckard HamelmannDoris Hartwig-Bade et al.

A2 Journal Article in ALLERGO JOURNAL INTERNATIONAL

Immunoregulatory effects of bone marrow-derived mesenchymal stem cells in the nasal polyp microenvironment

Rogerio PezatoDanilo Cândido de AlmeidaThiago Freire BezerraFernando de Sá SilvaClaudina Perez NovoLuis Carlos GregórioRichard Louis VoegelsNiels Olsen CâmaraClaus Bachert

A1 Journal Article in MEDIATORS OF INFLAMMATION

Integrated care pathways for airway diseases (AIRWAYS-ICPs)

J BousquetA AddisI AdcockI AgachéA AgustiA AlonsoI Annesi-MaesanoJM AntoClaus BachertCE Baena-Cagnani et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Intranasal corticosteroid treatment failure in allergic rhinitis : assessment of unmet need by measuring shift to multiple therapies

D PriceG ScaddingClaus BachertH SalehS NasserV CarterJ Von ZiegenweidtD Ryan

Is immunoglobulin E to Staphylococcus aureus enterotoxins associated with asthma at 20 years of age?

Ina SintobinT KeilS LauL GrabenhenrichGabriële HoltappelsA ReichU WahnClaus Bachert

MP29-02 (Dymista®) : eine neue Behandlungsoption für die allergische Rhinitis

L KlimekClaus BachertM WagenmannJ RingO Pfaar

A1 Journal Article in ALLERGOLOGIE

Mixed T helper cell signatures in chronic rhinosinusitis with and without polyps

Lara DeryckeStefanie EyerichKoen Van CrombruggenClaudina Perez NovoGabriële HoltappelsNatalie De RuyckPhilippe GevaertClaus Bachert

A1 Journal Article in PLOS ONE

Real-world effectiveness of a new allergic rhinitis therapy (MP29-02)

L KlimekJC VirchowU WahnR MoesgesU MunzelClaus Bachert

Replication study of genetic variants associated with chronic rhinosinusitis and nasal polyposis

Viktor HenmyrGriet VandeplasChrister HalldenTorbjorn SällHeidi OlzeClaus BachertLars Olaf Cardell

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Staphyloccoccus aureus elicit epithelial cell-derived cytokine productions in human nasal tissue

F LanNan ZhangDX WangOlga KryskoGabriële HoltappelsNG PapadopoulosSL JohnstonClaus Bachert

Staphylococcal enterotoxin sensitization in a community-based population : a potential role in adult-onset asthma

Woo-Jung SongYoon-Seok ChangMin Kyung LimE Hwa YunSae-Hoon KimHye-Ryun KangHeung-Woo ParkPeter TomassenMin-Ho ChoiKyung-Up Min et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Suppression of cytokine release by fluticasone furoate vs. mometasone furoate in human nasal tissue ex-vivo

Nan ZhangKoen Van CrombruggenGabriële HoltappelsFeng LanMichail KatotomichelakisLuo ZhangPetra HöggerClaus Bachert

A1 Journal Article in PLOS ONE

TMEM16A-mediated mucin production in IL-13-induced nasal epithelial cells from chronic rhinosinusitis patients

Y ZhangX WangH WangJ JiaoY LiE FanL ZhangClaus Bachert

The association of asthma, nasal allergies, and positive skin prick tests with obesity, leptin, and adiponectin

RB NewsonM JonesB ForsbergC JansonA BossiosS-E DahlenEM ToskalaA Al-KalemjiML KowalskiB Rymarczyk et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

The development of the MeDALL core questionnaires for a harmonized follow-up assessment of eleven European birth cohorts on asthma and allergies

Cynthia HohmannMariona PinartChristina TischerUlrike GehringJoachim HeinrichInger KullEric MelénHenriette A SmitMaties TorrentAlet H Wijga et al.

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

The effects of smoking on quality of life recovery after surgery for chronic rhinosinusitis

Michael KatotomichelakisEfthimios SimopoulosGregory TripsianisNan ZhangGerasimos DanielidesPanagiota GoumaClaus BachertVassilios Danielides

A1 Journal Article in RHINOLOGY

The expression of dendritic cell subsets in severe chronic rhinosinusitis with nasal polyps is altered

Rogerio PezatoClaudina Perez NovoGabriële HoltappelsNatalie De RuyckKoen Van CrombruggenGeert De VosClaus BachertLara Derycke

A1 Journal Article in IMMUNOBIOLOGY

The importance of local eosinophilia in the surgical outcome of chronic rhinosinusitis : a 3-year prospective observational study

Stephan VlaminckTom VauterinPeter W HellingsMark JorissenFrederic AckePaul Van CauwenbergeClaus BachertPhilippe Gevaert

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY & ALLERGY

The relation of airway obstruction to asthma, chronic rhinosinusitis and age: results from a population survey of adults

D ObasekiJ PottsGuy JoosJ BaelumT HaahtelaM AhlströmP MatricardiU KramerM GjomarkajW Fokkens et al.

A1 Journal Article in ALLERGY

Transforming growth factor-beta 1 pathways in inflammatory airway diseases

Y YangNan ZhangF LanKoen Van CrombruggenL FangG HuS HongClaus Bachert

A1 Journal Article in ALLERGY

Use of paper filter discs for measurement of local biomarkers of nasal mucosal inflammation

Margot BeringsLien CalusLien DevuystThibaut Van ZeleNatalie De RuyckClaus BachertPhilippe Gevaert

Vascular endothelial growth factor receptor 1 expression in nasal polyp tissue

S BobicV HoxI CallebautS VinckierB JonckxJ-M StassenM JorissenPhilippe GevaertP CarmelietClaus Bachert et al.

A1 Journal Article in ALLERGY

2013

A new allergic rhinitis therapy (MP29-02) is more effective than current first line monotherapies in providing allergic rhinitis patients relief from their nasal and ocular symptoms (rTNSS, rT5SS, rT7SS)

G CanonicaJ BousquetJ MullolJC VirchowU MunzelClaus Bachert

A new therapy (MP29-02) is effective for the long-term treatment of chronic rhinitis

D PriceS ShahS BhatiaClaus BachertW BergerJ BousquetW CarrP HellingsU MunzelG Scadding et al.

A1 Journal Article in JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY

Allergic fungal rhinosinusitis: more than a fungal disease?

Tineke DutréSurayie Al DousaryNan ZhangClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Bone grafts engineered from human adipose-derived stem cells in dynamic 3D-environments

Heidi DeclercqTamara De CaluwéOlga KryskoClaus BachertMaria Cornelissen

A1 Journal Article in BIOMATERIALS

Clinically relevant effect of a new intranasal therapy (MP29-02) in allergic rhinitis assessed by responder analysis

Eli MeltzerPaul RatnerClaus BachertWarner CarrWilliam BergerG Walter CanonicaJames HadleyPhil LiebermanFrank C HampelJoaquim Mullol et al.

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Damage‑associated molecular patterns and their receptors in upper airway pathologies

Koen Van CrombruggenFenila JacobNan ZhangClaus Bachert

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Endotypes and phenotypes of chronic rhinosinusitis : a PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology

Cezmi A AkdisClaus BachertCemal CingiMark S DykewiczPeter W HellingsRobert M NaclerioRobert P SchleimerDennis Ledford

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Epithelium and stroma from nasal polyp mucosa exhibits inverse expression of TGF-β1 as compared with healthy nasal mucosa

Leonardo BalsalobreRogerio PezatoClaudina Perez NovoMaria Teresa S AlvesRodrigo P SantosClaus BachertLuc LM Weckx

A1 Journal Article in JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

Forkhead box P3 in human airway regulatory T cells is regulated by suppressor of cytokine signaling

F LanNan ZhangJ ZhangOlga KryskoQ ZhangJ XianLara DeryckeY QiK LiS Liu et al.

Forkhead box protein 3 in human nasal polyp regulatory T cells is regulated by the protein suppressor of cytokine signaling 3

Feng LanNan ZhangJie ZhangOlga KryskoQuanbo ZhangJunming XianLara DeryckeYanyu QiKai LiShixi Liu et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

From phenotype to endotype in chronic rhinosinusitis

Peter TomassenJestinah Mahachie JohnClaus Bachert

Immunomodulatory effects of IL-23 and IL-17 in a mouse model of allergic rhinitis

M WangW ZhangJ ShangJ YangL ZhangClaus Bachert

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Local receptor revision and class switching to IgE in chronic rhinosinusitis with nasal polyps

Philippe GevaertKayhan T Nouri-AriaHuiFen WuClaire E HarperPooja TakharDavid J FearFrederic AckeNatalie De RuyckGraham BanfieldHarsha H Kariyawasam et al.

A1 Journal Article in ALLERGY

Many faces of DAMPs in cancer therapy

Olga KryskoTania Love AaesClaus BachertPeter VandenabeeleDmitri Krysko

A1 Journal Article in CELL DEATH & DISEASE

MicroRNA: a new approach to treat different endotypes of nasal polyps

Peng ZhouShixi LiuClaus Bachert

A1 Journal Article in MEDICAL HYPOTHESES

Nasal allergen provocation test in nasal polyposis with and without allergy

Lien CalusLien DevuystNatalie De RuyckThibaut Van ZeleClaus BachertPhilippe Gevaert

Nasal provocation, skin reactivity and allergen-specific serum IgE levels in allergic rhinitis

M NellD BootHE NienhuisE van TwuijverO PfaarClaus Bachert

Nasopharyngeal bacterial colonization in asthmatic children and healthy controls

E RoumpedakiP XepapadakiA DoudoulakakisE LebessiM PassiotiC SkevakiP TaprantziM TsakanikosM TsoliaT Dutre et al.

Novel efficacy parameters in allergic rhinitis management : results with a new allergic rhinitis therapy (MP29-02)

W CarrGW CanonicaClaus BachertW BergerU MunzelJ Bousquet

Olfactory dysfunction and asthma as risk factors for poor quality of life in upper airway diseases

Michael KatotomichelakisEfthimios SimopoulosNan ZhangGregory TripsianisGerasimos DanielidesMiltos LivaditisClaus BachertVassilios Danielides

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY & ALLERGY

Omalizumab is effective in allergic and nonallergic patients with nasal polyps and asthma

Philippe GevaertLien CalusThibaut Van ZeleKatrien BlommeNatalie De RuyckWOUTER BAUTERSPeter HellingsGuy BrusselleDirk De BacquerPaul Van Cauwenberge et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Polymorphisms in thymic stromal lymphopoietin gene demonstrate a gender and nasal polyposis-dependent association with chronic rhinosinusitis

Yuan ZhangXiangdong WangWei ZhangDemin HanLuo ZhangClaus Bachert

A1 Journal Article in HUMAN IMMUNOLOGY

Pooling birth cohorts in allergy and asthma: European Union-funded initiatives: a MeDALL, CHICOS, ENRIECO, and GA²LEN joint paper

Jean BousquetJosep AntoJordi SunyerMark NieuwenhuijsenMartine VrijheidThomas Keilthe MeDALL Study GroupBart LambrechtClaus Bachertthe GA²LEN Study Group et al.

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Prevalence of allergic sensitization versus allergic rhinitis symptoms in an unselected population

Katrien BlommePeter TomassenHilde LapeereWouter HuvenneMichiel BonnyFrederic AckeClaus BachertPhilippe Gevaert

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Purinergic signaling in inflammatory cells: P2 receptor expression, functional effects, and modulation of inflammatory responses

Fenila JacobClaudina Perez NovoClaus BachertKoen Van Crombruggen

A1 Journal Article in PURINERGIC SIGNALLING

Role of staphylococcal superantigens in airway disease

Wouter HuvennePeter W HellingsClaus Bachert

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Should clinicians use omalizumab for the treatment of nasal polyps?: reply

Lien CalusPeter HellingsGuy BrusselleClaus BachertPhilippe Gevaert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sputum IgE and cytokines in asthma : relationship with sputum cellular profile

Maïté ManiseGabriële HoltappelsKoen Van CrombruggenFlorence SchleichClaus BachertRenaud Louis

A1 Journal Article in PLOS ONE

Staphylococcal enterotoxin B influences the DNA methylation pattern in nasal polyp tissue : a preliminary study

Claudina Perez NovoYuan ZhangSimon DenilGeert TrooskensTim De MeyerWim Van CriekingePaul Van CauwenbergeLuo ZhangClaus Bachert

A1 Journal Article in ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY

Staphylococcus aureus enterotoxin-speciﬁc IgE is associated with asthma in the general population: a GA²LEN study

Peter TomassenD JarvisR NewsonR Van ReeB ForsbergP HowarthC JansonML KowalskiU KrämerPM Matricardi et al.

A1 Journal Article in ALLERGY

TNF/TNF-R1 pathway is involved in doxorubicin-induced acute sterile inflammation

Agnieszka KaczmarekOlga KryskoLiesbeth HeyndrickxTania Love AaesTinneke DelvaeyeClaus BachertLuc LeybaertPeter VandenabeeleDmitri Krysko

A1 Journal Article in CELL DEATH & DISEASE

The Slug Mucosal Irritation (SMI) assay: a tool for the evaluation of nasal discomfort

Joke LenoirClaus BachertJean Paul RemonEls Adriaens

A1 Journal Article in TOXICOLOGY IN VITRO

The adjuvant-like activity of staphylococcal enterotoxin B in a murine asthma model is independent of IL-1R signaling

Olga KryskoTania MaesMaud PlantingaGabriële HoltappelsRosina ImiruPeter VandenabeeleGuy JoosDmitri KryskoClaus Bachert

A1 Journal Article in ALLERGY

The development of nasal polyp disease involves early nasal mucosal inflammation and remodelling

Juan MengPeng ZhouYafeng LiuXuelian YiShixi LiuGabriële HoltappelsClaus BachertNan Zhang

A1 Journal Article in PLOS ONE

The importance of local eosinophilia in the surgical outcome of chronic rhinosinusitis : a 3-year prospective observational study

Stephan VlaminckTom VauterinPeter HellingsMark JorissenFrederic AckePaul Van CauwenbergePhilippe GevaertClaus Bachert

The new allergic rhinitis therapy (MP29-02) effectively treats patients with seasonal allergic rhinitis regardless of their predominant symptom

Claus BachertP LiebermanG ScaddingP RatnerU MunzelJ Bousquet

The pathogenesis of CRS : an update

Claus BachertNada Al BahraniSurayie Al DousaryKoen Van CrombruggenOlga KryskoClaudina Perez NovoNan Zhang

A2 Journal Article in CURRENT OTORHINOLARYNGOLOGY REPORTS

Uncontrolled allergic rhinitis and chronic rhinosinusitis: where do we stand today?

pW HellingsWJ FokkensC AkdisClaus BachertC CingiD Dietz de LoosPhilippe GevaertV HoxL KalogjeraV Lund et al.

A1 Journal Article in ALLERGY

What we should learn from the London Olympics

M BoniniClaus BachertCE Baena-CagnaniA BedbrookJL BrozekGW CanonicaAA CruzWJ FokkensR Gerth van WijkL Grouse et al.

Editorial material

2012

A herbal composition of Scutellaria baicalensis and Eleutherococcus senticosus shows potent anti-inflammatory effects in an ex vivo human mucosal tissue model

Nan ZhangKoen Van CrombruggenGabriële HoltappelsClaus Bachert

A1 Journal Article in EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE

A novel intranasal therapy of azelastine with fluticasone for the treatment of allergic rhinitis

Warner CarrJonathan BernsteinPhil LiebermanEli MeltzerClaus BachertDavid PriceUllrich MunzelJean Bousquet

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs

J BousquetHJ SchunemannB SamolinskiP DemolyCE Baena-CagnaniClaus BachertS BoniniLP BouletPJ BousquetJL Brozek et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma in adults and its association with chronic rhinosinusitis: the GA2LEN survey in Europe

Deborah JarvisRoger NewsonJan LotvallDeniz HastanPeter TomassenT KeilM GjomarkajB ForsbergM GunnbjornsdottirJ Minov et al.

A1 Journal Article in ALLERGY

Bone grafts engineered from human adipose-derived stem cells in dynamic 3d-environments : a top-down versus bottom-up approach

Heidi DeclercqTamara De CaluwéOlga KryskoClaus BachertMaria Cornelissen

Chronic rhinosinusitis and asthma: novel understanding of the role of IgE 'above atopy'

Claus BachertNan Zhang

A1 Journal Article in JOURNAL OF INTERNAL MEDICINE

Chronic rhinosinusitis: from one disease to different phenotypes

Claus BachertNan ZhangThibaut Van ZelePhilippe Gevaert

A1 Journal Article in PEDIATRIC ALLERGY AND IMMUNOLOGY

Clinical efficacy of a dry extract of five herbal drugs in acute viral rhinosinusitis

R JundM MondiglerH SteindlH StammerP StiernaClaus Bachert

A1 Journal Article in RHINOLOGY

Comparison of intranasal azelastine to intranasal fluticasone propionate for symptom control in moderate-to-severe seasonal allergic rhinitis

Warner W CarrPaul RatnerUllrich MunzelRuth MurrayDavid PriceG Walter CanonicaJoaquim MullolJ Christian VirchowPhil LiebermanEli Meltzer et al.

A1 Journal Article in ALLERGY AND ASTHMA PROCEEDINGS

Cytokine profiles in Japanese patients with chronic rhinosinusitis

Takayuki SejimaGabriële HoltappelsHisashi KikuchiShoichiro ImayoshiKeiichi IchimuraClaus Bachert

A1 Journal Article in ALLERGOLOGY INTERNATIONAL

Development of a novel model for comparative evaluation of intranasal pharmacokinetics and effects of anti-allergic nasal sprays

Daniel BaumannClaus BachertPetra Högger

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Die chronische Rhinosinusitis in Europa: eine Zusammenfassung epidemiologischer Arbeiten von GA²LEN

H OlzeT ZuberbierClaus Bachert

A1 Journal Article in ALLERGOLOGIE

EPOS 2012 : European position paper on rhinosinusitis and nasal polyps 2012 : a summary for otorhinolaryngologists

Wytske J FokkensValerie I LundJoachim MullolClaus BachertIsam AlobidFuad BaroodyNoam CohenAnders CervinRichard DouglasPhilippe Gevaert et al.

A1 Journal Article in RHINOLOGY

Efficient derivation of mesenchymal stem cells from human embryonic stem cells for tissue engineering

Heidi DeclercqWai TamOlga KryskoClaus BachertMaria Cornelissen

Episode pattern and healthcare utilisation in patients with seasonal allergic rhinitis

R PitmanN ParachaC ParkerS AcasterClaus BachertJ BousquetD Price

Establishing the place in therapy of bilastine in the treatment of allergic rhinitis according to ARIA: evidence review

Jean BousquetIgnacio AnsóteguiG Walter CanonicaTorsten ZuberbierCarlos E Baena-CagnaniClaus BachertAlvaro A CruzSandra N GonzálezPiotr KunaMario Morais-Almeida et al.

A1 Journal Article in CURRENT MEDICAL RESEARCH AND OPINION

European position paper on rhinosinusitis and nasal polyps 2012

Wytske J FokkensValerie I LundJoachim MullolClaus BachertIsam AlobidFuad BaroodyNoam CohenAnders CervinRichard DouglasPhilippe Gevaert et al.

A1 Journal Article in RHINOLOGY

Executive summary of European Task Force document on diagnostic tools in rhinology

P. W. HellingsG. ScaddingI. AlobidClaus BachertW. J. FokkensR. Gerth van WijkPhilippe GevaertJ. GuilemanyL. KalogjeraV. J. Lund et al.

A1 Journal Article in RHINOLOGY

GA(2)LEN sinusitis cohort study: chronic rhinosinusitis -differentiation based on chemokine pattern and IL-5

H OlzeU FoersterL CardellW FokkensP HellingsM KowalskiJ MullolE ToskalaPeter TomassenClaus Bachert

Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue

XiangDong WangNan ZhangSarah GlorieuxGabriële HoltappelsMario VaneechoutteOlga KryskoLuo ZhangDeMin HanHans NauwynckClaus Bachert

A1 Journal Article in PLOS ONE

IL-17A as a regulator of neutrophil survival in nasal polyp disease of patients with and without cystic fibrosis

Lara DeryckeNan ZhangGabriële HoltappelsTineke DutréClaus Bachert

A1 Journal Article in JOURNAL OF CYSTIC FIBROSIS

IL-21 is increased in nasal polyposis and after stimulation with Staphylococus aureus enterotoxins

Lien CalusIne DeryckeNatalie De RuyckGabriële HoltappelsMelissa DullaersBart LambrechtClaus BachertPhilippe Gevaert

Improvement of chronic rhinitis under aspirin

Christos MerkonidisVolker GudziolMariapaola Paola CecchiniJohannes GerberHan-Seok SeoClaus BachertThomas Hummel

A1 Journal Article in RESPIRATORY CARE

Increased expression of IL-19 in the epithelium of patients with chronic rhinosinusitis and nasal polyps

E PaceV ScafidiD Di BonaL SienaG ChiapparaM FerraroS La GruttaS GallinaR SpecialeA Ballacchino et al.

A1 Journal Article in ALLERGY

Inflammation and remodelling patterns in early stage chronic rhinosinusitis

Nicholas Van BruaeneClaudina Perez NovoKoen Van CrombruggenNatalie De RuyckGabriële HoltappelsPaul Van CauwenbergePhilippe GevaertClaus Bachert

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Intranasal azelastine (2 sprays/nostril twice daily) vs intranasal fluticasone propionate (2 sprays/nostril once daily) for the treatment of patients with seasonal allergic rhinitis over a 14-day period

W CarrP RatnerClaus BachertP LiebermanE MeltzerU MunzelD Price

Intranasal azelastine/fluticasone propionate formulation: a novel therapy for the treatment of chronic rhinitis: safety data from a 12 month-trial

D PriceJ BousquetClaus BachertW BergerW CarrU MunzelP Lieberman

Leitlinie 'Rhinosinusitis' Langfassung: S2-Leitlinie der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- un Hals-Chirurgie

BA StuckClaus BachertP FederspilW HosemannL KlimekR MösgesO PfaarC RudackH SitterM Wagenmann et al.

A1 Journal Article in HNO

Local free light chain expression is increased in chronic rhinosinusitis with nasal polyps

T Groot KormelinkLien CalusNatalie De RuyckGabriële HoltappelsClaus BachertFA RedegeldPhilippe Gevaert

A1 Journal Article in ALLERGY

Local inflammation in chronic upper airway disease

Lien CalusThibaut Van ZeleLara DeryckeOlga KryskoTineke DutréPeter TomassenMelissa DullaersClaus BachertPhilippe Gevaert

A1 Journal Article in CURRENT PHARMACEUTICAL DESIGN

MP29-02 is effective for the symptomatic treatment of seasonal allergic rhinitis even in those with very severe disease: a meta-analysis

J BousquetW CarrJ BernsteinP LiebermanE MeltzerClaus BachertU MunzelD Price

Mometasone furoate nasal spray increases the number of minimal-symptom days in patients with acute rhinosinusitis

Eli O MeltzerDavis GatesClaus Bachert

A1 Journal Article in ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Omalizumab is effective in allergic and non-allergic patients with nasal polyps and asthma

Philippe GevaertLien CalusThibaut Van ZeleKatrien BlommeNatalie De RuyckWOUTER BAUTERSP HellingsDirk De BacquerGuy BrussellePaul Van Cauwenberge et al.

Practical guide to skin prick tests in allergy to aeroallergens

J BousquetL HeinzerlingClaus BachertNG PapadopoulosPJ BousquetPG BurneyGW CanonicaKH CarlsenL CoxT Haahtela et al.

A1 Journal Article in ALLERGY

Prevalence of chronic rhinosinusitis in São Paulo

Renata Ribeiro PilanFabio de Rezende PinnaThiago Freire BezerraRenata Lopes MoriFrancini Grecco PaduaRicardo Ferreira BentoClaudina Perez NovoClaus BachertRichard Louis Voegels

A1 Journal Article in RHINOLOGY

RAGE processing in chronic airway conditions: involvement of Staphylococcus aureus and ECP

Koen Van CrombruggenGabriële HoltappelsNatalie De RuyckLara DeryckePeter TomassenClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rhinosinusitis and asthma

Claus BachertPhilippe GevaertThibaut Van ZeleFrederic Acke

Bookchapter in Scientific basis of healthcare : asthma

Role of Staphylococcus aureus Enterotoxin B in the aggravation of airway inflammation

Wouter HuvenneClaus BachertPeter Hellings

Role of imbalance of eicosanoid pathways and staphylococcal superantigens in chronic rhinosinusitis

Rogerio PezatoMonika Swierczyńska-KrępaEwa Niżankowska-MogilnickaLara DeryckeClaus BachertClaudina Perez Novo

A1 Journal Article in ALLERGY

SIT: efficacy depends on product, not on route of application

Claus BachertG Walter CanonicaAlbrecht Bufe

A1 Journal Article in PEDIATRIC ALLERGY AND IMMUNOLOGY

Severe chronic allergic (and related) diseases : a uniform approach: a MeDALL-GA²LEN-ARIA position paper

J BousquetJM AntoP DemolyHJ SchünemannA TogiasM AkdisC AuffrayClaus BachertT BieberPJ Bousquet et al.

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Single nucleotide polymorphisms in thymic stromal lymphopoietin gene are not associated with allergic rhinitis susceptibility in Chinese subjects

Yuan ZhangXiaohong SongYanming ZhaoLuo ZhangClaus Bachert

A1 Journal Article in BMC MEDICAL GENETICS

Specific IgE against Staphylococcus aureus enterotoxins: an independent risk factor for asthma

Claus BachertKristel Van SteenNan ZhangGabriële HoltappelsTom CattaertBärbel MausRoland BuhlChristian TaubeStephanie KornMarek Kowalski et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Systematic review protocol to define classical IgE-associated diseases from birth to adolescence: the MeDALL study

M PinartD MaierE Gimeno-SantosI SolaJ Garcia-AymerichS GuerraR SteinM BenetK CarlsenM Herr et al.

TGF-beta in chronic sinus diseases: from immuneregulation to remodeling

Nicholas Van BruaeneClaus BachertPhilippe Gevaert

Transforming growth factor-beta1 in inflammatory airway disease: a key for understanding inflammation and remodeling

YC YangNan ZhangKoen Van CrombruggenGH HuSL HongClaus Bachert

A1 Journal Article in ALLERGY

Treatment preferences in patients with moderate-severe seasonal allergic rhinitis: findings of a discrete choice experiment

S AcasterW CarrP LiebermanClaus BachertD Price

Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar

Josep M AntóMariona PinartMübeccel AkdisCharles AuffrayClaus BachertXavier BasagañaKai-Håkon CarlsenStefano GuerraLeena von HertzenSabina Illi et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Wirksamkeit von Präparaten mit nicht modifizierten Allergenen zur sublingualen : Evidenzbewertung anhand klinischer Studien

A1 Journal Article in ALLERGOLOGIE

2011

Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component

Diana MechtcheriakovaYury SobanovGabriele HoltappelsErika BajnaMartin SvobodaMarkus JaritzClaus BachertErika Jensen-Jarolim

A1 Journal Article in PLOS ONE

Adaptive immune responses in Staphylococcus aureus biofilm-associated chronic rhinosinusitis

A ForemanG HoltappelsAJ PsaltisJ Jervis-BardyJ FieldPJ WormaldClaus Bachert

A1 Journal Article in ALLERGY

Alternatively activated macrophages and impaired phagocytosis of S-aureus in chronic rhinosinusitis

Olga KryskoGabriële HoltappelsNan ZhangMalgorzata KubicaKim DeswarteLara DeryckeSofie ClaeysHamida HammadGuy BrussellePeter Vandenabeele et al.

A1 Journal Article in ALLERGY

Assessment of sleep impairment in persistent allergic rhinitis patients using polysomnography

J MengJ XuanX QiaoX LiS LiuKF LukatNan ZhangClaus Bachert

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Association of asthma with IgE to staphylococcal enterotoxins in a GA2LEN population based case-control study

Peter TomassenClaus BachertPeter BurneyDeborah Jarvis

Capsaicin-induced vasodilatation in human nasal vasculature is mediated by modulation of cyclooxygenase-2 activity and abrogated by sulprostone

Koen Van CrombruggenLuc Van NassauwLara DeryckeJean-Piere TimmermansGabriële HoltappelsDavid HallClaus Bachert

A1 Journal Article in NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Chronic rhinosinusitis and nasal polyps: clinical data from the Berlin cohort

Ulrike FoersterPeter TomassenClaus BachertHeidi Olze

Chronic rhinosinusitis in Europe: an underestimated disease: a GA²LEN study

D HastanWJ FokkensClaus BachertRB NewsonJ BislimovskaA BockelbrinkPJ BousquetG BrozekA BrunoSE Dahlén et al.

A1 Journal Article in ALLERGY

Chronic rhinosinusitis in Europe: an underestimated disease: a GA²LEN study

Deniz HastanWytske FokkensClaus BachertPeter TomassenRoger NewsonDeborah JarvisJovanka BislimovskaAngelina BockelbrinkPhilippe-Jean BousquetJean Bousqueta et al.

Clinical and immunological determinants of severe/refractory asthma (SRA): association with Staphylococcal superantigen-specific IgE antibodies

ML KowalskiM CieslakClaudina Perez NovoJS MakowskaClaus Bachert

A1 Journal Article in ALLERGY

Diagnostic tools in Rhinology EAACI position paper

Glenis ScaddingPeter HellingsIsam AlobidClaus BachertWytske FokkensRoy Gert van WijkPhilippe GevaertJosep GuilemanyLivije KalogjeraValerie Lund et al.

A2 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

Efficacy and safety of mometasone furoate nasal spray in the treatment of chronic rhinosinusitis

R MösgesClaus BachertC RudackB HauswaldL KlimekJ SpaethG RaspJ VentK Hörmann

A1 Journal Article in ADVANCES IN THERAPY

Efficacy of second-generation antihistamines in patients with allergic rhinitis and comorbid asthma

Claus BachertJorge Maspero

A1 Journal Article in JOURNAL OF ASTHMA

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

Dmitri KryskoPatrizia AgostinisOlga KryskoAbhishek D GargClaus BachertBart LambrechtPeter Vandenabeele

A1 Journal Article in TRENDS IN IMMUNOLOGY

Epidemiology of upper airway disease in an urban population: smoking is a risk factor for acute and chronic rhinosinusitis

Peter TomassenDeniz HastanNicholas Van BruaeneThibaut Van ZeleWytske FokkensPeter BurneyClaus Bachert

European view on the pathology of chronic rhinosinusitis, nasal polyposis and the impact of staphylococcal enterotoxins: first results of the Ga2len sinusitis cohort study

Peter TomassenLars-Olaf CardellNatalie De RuyckUlrike FoersterWytske FokkensPhilippe GevaertPeter HellingsValérie HoxElina KatainenMarek Kowalski et al.

European view on the pathology of chronic rhinosinusitis, nasal polyposis and the impact of staphylococcal enterotoxins: first results of the Ga2len sinusitis cohort study

Peter TomassenLars-Olaf CardellNatalie De RuyckUlrike FoersterWytske FokkensPhilippe GevaertPeter HellingsValérie HoxElina KatainenMarek Kowalski et al.

Ex-vivo model to stimulate nasal tissue and new therapeutic targets

Joke PatouClaus BachertPhilippe Gevaert

Exacerbation of cigarette smoke-induced pulmonary inflammation by Staphylococcus aureus enterotoxin B in mice

Wouter HuvenneEllen LanckackerOlga KryskoKen BrackeTine DemoorPeter W HellingsGuy BrusselleGuy JoosClaus BachertTania Maes

A1 Journal Article in RESPIRATORY RESEARCH

GA2LEN sinusitis cohort study: chronic Rhinosinusitis with nasal polyps: differentiation based on chemokine pattern

Heidi OlzeUlrike FörsterLars-Olaf CardellWytske FokkensMarek KowalskiPeter HellingsJoaquim MullolElina ToskalaPeter TomassenClaus Bachert

Genetic variation in the toll-like receptor gene family and chronic rhinosinusitis: a GA2LEN pilot study

Daniel NilssonClaus BachertWytske FokkensPeter HellingsMarek KowalskiJoaquim MullolHeidi OlzePeter TomassenElina ToskalaChrister Halldén et al.

Herpes Simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosa

Sarah GlorieuxClaus BachertHerman FavoreelAnnelies VandekerckhoveLennert SteukersAnamaria RekeckiWim Van Den BroeckR ClaytonHans Nauwynck

Herpes simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosa

Sarah GlorieuxClaus BachertHerman FavoreelAnnelies VandekerckhoveLennert SteukersAnamaria RekeckiWim Van Den BroeckJoline GoossensSiska CroubelsReginald F Clayton et al.

A1 Journal Article in PLOS ONE

How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an ARIA-GA2LEN statement

J BousquetHJ SchünemannPJ BousquetClaus BachertGW CanonicaTB CasaleP DemolyS DurhamK-H CarlsenH-J Malling et al.

A1 Journal Article in ALLERGY

Increased nasal IL-5 levels act as a predisposing factor of asthma in southern China reply

Claus BachertNan ZhangGabriële HoltappelsPeter TomassenShixi LiuPing LinJean Bousquet

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine

J BousquetJ AntoC AuffrayM AkdisA Cambon-ThomsenT KeilT HaahtelaBart LambrechtDS PostmaJ Sunyer et al.

A1 Journal Article in ALLERGY

Mepolizumab, a humanized anti-IL-5 mAb, as a treatment option for severe nasal polyposis

Philippe GevaertNicholas Van BruaeneTom CattaertKristel Van SteenThibaut Van ZeleFrederic AckeNatalie De RuyckKatrien BlommeAnna SousaRichard Marshall et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mucosal tissue polyclonal IgE is functional in response to allergen and SEB

Nan ZhangGabriële HoltappelsPhilippe GevaertJoke PatouB DhaliwalHannah GouldClaus Bachert

A1 Journal Article in ALLERGY

Nasal secretion assays predict superantigen involvement in nasal polyposis

Peter TomassenLars-Olaf CardellNatalie De RuyckUlrike FoersterWytske FokkensPhilippe GevaertPeter HellingsValérie HoxElina KatainenMarek Kowalski et al.

Pathogenesis of chronic rhinosinusitis: inflammation

Koen Van CrombruggenNan ZhangPhilippe GevaertPeter TomassenClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pathophysiology of chronic rhinosinusitis

Peter TomassenThibaut Van ZeleNan ZhangClaudina Perez NovoNicholas Van BruaenePhilippe GevaertClaus Bachert

A2 Journal Article in PROCEEDINGS OF THE AMERICAN THORACIC SOCIETY

Staphylococcal enterotoxin specific IgE in serum is linked to severe asthma and nasal polyposis

Peter TomassenLars-Olaf CardellNatalie De RuyckUlrike FörsterWytske FokkensPhilippe GevaertPeter HellingsValérie HoxElina KatainenMarek Kowalski et al.

TLR-2 and TLR-9 are sensors of apoptosis in a mouse model of doxorubicin-induced acute inflammation

Dmitri KryskoAgnieszka KaczmarekOlga KryskoLiesbeth HeyndrickxJerzy WoznickiPieter BogaertAnje CauwelsNozomi TakahashiS MagezClaus Bachert et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

The association between bacterial colonization and inflammatory pattern in Chinese chronic rhinosinusitis patients with nasal polyps

L BaNan ZhangJ MengJ ZhangP LinP ZhouS LiuClaus Bachert

A1 Journal Article in ALLERGY

Therapeutic Index (TIX) for intranasal corticosteroids in the treatment of allergic rhinitis

T SchäferM SchnoorM WagenmannL KlimekClaus Bachert

A1 Journal Article in RHINOLOGY

Tissue remodeling in chronic rhinosinusitis

Nicholas Van BruaeneClaus Bachert

A1 Journal Article in CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY

2010

Bilastine in allergic rhinoconjunctivitis and urticaria

Claus BachertP KunaTorsten Zuberbier

A1 Journal Article in Allergy

CRTH2 mediates the activation of human Th2 cells in response to PGD2 released from IgE/anti-IgE treated nasal polyp tissue

Claudina Perez NovoGabriële HoltappelsShân L VinallLuzheng XueNan ZhangClaus BachertRoy Pettipher

A1 Journal Article in ALLERGY

Chronic sinusitis and rhinitis: clinical terminology 'chronic rhinosinusitis' further supported

Koen Van CrombruggenNicholas Van BruaeneGabriële HoltappelsClaus Bachert

A1 Journal Article in RHINOLOGY

Development and implementation of guidelines in allergic rhinitis: an ARIA-GA2LEN paper

J BousquetHJ SchunemannT ZuberbierClaus BachertCE Baena-CagnaniPJ BousquetJ BrozekGW CanonicaTB CasaleP Demoly et al.

A1 Journal Article in ALLERGY

Different regulation of cigarette smoke induced inflammation in upper versus lower airways

Wouter HuvenneClaudina Perez NovoLara DeryckeNatalie De RuyckOlga KryskoTania MaesNele PauwelsLander RobaysKen BrackeGuy Joos et al.

A1 Journal Article in RESPIRATORY RESEARCH

Efficacy of desloratadine in persistent allergic Rhinitis: a GA(2)LEN study

Jean BousquetClaus BachertGiorgio W CanonicaJoaquim MullolPaul Van CauwenbergeCarsten Bindslev JensenWystke J FokkensJohannes RingPaul KeithGokul Gopalan et al.

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

European view on the immunopathology of nasal polyposis: first results of the GA²LEN sinusitis cohort study

Peter TomassenClaus Bachert

Expression of TGF, matrix metalloproteinases, and tissue inhibitors in Chinese chronic rhinosinusitis

Xiaoyuan LiJuan MengXiaoming QiaoYafeng LuiFeng LiuNan ZhangJie ZhangGabriële HoltappelsBa LuoPeng Zhuo et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

GA(2)LEN/EAACI pocket guide for allergen-specific immunotherapy for allergic rhinitis and asthma

T ZuberbierClaus BachertPJ BousquetG PassalacquaGW CanonicaH MerkM WormU WahnJ Bousquet

A1 Journal Article in ALLERGY

GA²LEN study: prevalence of chronic rhinosinusitis in Europe by EP3OS criteria

Deniz HastanWytske FokkensClaus BachertElina ToskalaRuth HoffmansPeter TomassenJurriaan KokYvette SmuldersJames PottsRoger Newson et al.

Identification of the nasal mucosa as a new target for leptin action

Jasmien TaildemanPieter DemetterIsabelle RottiersGabriële HoltappelsClaus BachertClaude CuvelierClaudina Perez Novo

A1 Journal Article in HISTOPATHOLOGY

Impact of staphylococcus aureus superantigens on inflammation in chronic rhinosinusitis with nasal polyps in a paneuropean population: a Ga2len study

Peter TomassenClaus BachertSinusitis Cohort Study Working Group Ga²len

Impairment of phagocytosis of apoptotic cells and its role in chronic airway diseases

Olga KryskoPeter VandenabeeleDmitri KryskoClaus Bachert

A1 Journal Article in APOPTOSIS

Incidence and risk factors of acute rhinosinusitis in an urban population: a GA²LEN study

Peter TomassenThibaut Van ZeleJestinah MahachieNicholas Van BruaenePeter BurneyWytske FokkensClaus Bachert

Increased serum-soluble interleukin-5 receptor alpha level precedes the development of eczema in children

Aida Semic-JusufagicPhilippe GevaertClaus BachertClare MurrayAngela SimpsonAdnan Custovic

A1 Journal Article in PEDIATRIC ALLERGY AND IMMUNOLOGY

Inflammatory profiles in nasal mucosa of patients with persistent vs intermittent allergic rhinitis

F LiuJ ZhangY LiuNan ZhangGabriële HoltappelsP LinS LiuClaus Bachert

A1 Journal Article in ALLERGY

Oral steroids and doxycycline: Two different approaches to treat nasal polyps

Thibaut Van ZelePhilippe GevaertGabriële HoltappelsAchim BeulePeter John WormaldSusanne MayrGreet HensPeter HellingsFenna EbbensWytske Fokkens et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Plasticity of the dendritic cells to activate T cells in chronic rhinosinusitis

Lara DeryckeClaus BachertGabriële Holtappels

A1 Journal Article in ALLERGY

Praktische Allergologie

Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma

Claus BachertNan ZhangGabriële HoltappelsLizzy De LobelPaul Van CauwenbergeShiXi LiuPing LinJean BousquetKristel Van Steen

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Prevalence and risk factors of upper airway disease and allergy in Europe – the GA2LEN survey in a Belgian urban population.

Peter TomassenPeter BurneyNicholas Van BruaeneClaus Bachert

Remodeling and inflammation in Chinese versus white patients with chronic rhinosinusitis

Nan ZhangShixi LiuPing LinXiaoyuan LiNicholas Van BruaeneJie ZhangThibaut Van ZeleClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rhinosinusitis and asthma : a link for asthma severity

Claus BachertSofie ClaeysPeter TomassenThibaut Van ZeleNan Zhang

A1 Journal Article in CURRENT ALLERGY AND ASTHMA REPORTS

Staphylococcus aureus and chronic airway disease

Lara DeryckeClaudina Perez NovoKoen Van CrombruggenMarie-Noëlle CorriveauClaus Bachert

A2 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

Staphylococcus aureus enterotoxin B augments granulocyte migration and survival via airway epithelial cell activation

Wouter HuvenneIna CallebautKristien ReekmansGreet HensSonja BobicMark JorissenDominique BullensJan CeuppensClaus BachertPeter Hellings

A1 Journal Article in ALLERGY

Staphylococcus aureus enterotoxin B facilitates allergic sensitization in experimental asthma

Wouter HuvenneIna CallebautMaud PlantingaJeroen AJ VanoirbeekOlga KryskoDominique MA BullensPhilippe GevaertPaul Van CauwenbergeBart LambrechtJan L Ceuppens et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Staphylococcus aureus-derived superantigens in nasal polyp disease

Peter TomassenThibaut Van ZelePhilippe GevaertNan ZhangClaudina Perez NovoNicholas Van BruaeneJoke PatouClaus Bachert

Bookchapter in Nasal polyposis : pathogenesis, medical and surgical treatment

T cell inflammatory response, Foxp3 and TNFRS18-L regulation of peripheral blood mononuclear cells from patients with nasal polyps-asthma after staphylococcal superantigen stimulation

Claudina Perez NovoMonica Jedrzejczak-CzechowiczA Lewandowska-PolakCindy ClaeysGabriële HoltappelsPaul Van CauwenbergeML KowalskiClaus Bachert

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Th2-associated immunity to bacteria in teenagers and susceptibility to asthma

Elysia M HollamsBJ HalesClaus BachertWouter HuvenneF ParsonsNH de KlerkM SerralhaBJ HoltS AhlstedtWR Thomas et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

The impact of concomitant rhinitis on asthma-related quality of life and asthma control

O VandenplasM DramaixGuy JoosR LouisA MichilsG VerledenW VinckenAM VintsE HerbotsClaus Bachert

A1 Journal Article in ALLERGY

The prevalence of sensitization and relevant symptoms of allergic rhinitis in an unselected Belgium population

Katrien BlommeHilde LapeereWouter HuvenneMichiel BonnyFrederic AckeClaus BachertPhilippe Gevaert

Uncontrolled allergic rhinitis during treatment and its impact on quality of life: a cluster randomized trial

Philippe J BousquetClaus BachertGiorgo W CanonicaThomas B CasaleJoaquim MullolJean Michel KlossekTorsten ZuberbierJean Bousquet

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

2009

A Review of the Efficacy of Desloratadine, Fexofenadine, and Levocetirizine in the Treatment of Nasal Congestion in Patients With Allergic Rhinitis

A1 Journal Article in CLINICAL THERAPEUTICS

ARIA update 2008: allergic rhinitis and its effect on asthma

J BousquetN KhaltaevAA CruzJ DenburgW FokkensA TogiasT ZuberbierC Baena-CagnaniGW CanonicaC van Weel et al.

A1 Journal Article in ALLERGOLOGIE

Allergology in transition

Thomas WerfelClaus Bachert

Editorial material

Anti-IgE for the Treatment of Allergic Rhinitis and Eventually Nasal Polyps?

Katia VerbruggenPaul Van CauwenbergeClaus Bachert

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Chronic rhinosinusitis with and without nasal polyps: what is the difference?

Wouter HuvenneNicholas Van BruaeneNan ZhangThibaut Van ZeleJoke PatouPhilippe GevaertSofie ClaeysPaul Van CauwenbergeClaus Bachert

A1 Journal Article in Current Allergy and Asthma Reports

Comment on "Potent Phagocytic Activity with impaired Antigen Presentation Identifying Lipopolysaccharide-Tolerant Human Monocytes: Demonstration in Isolated Monocytes from Cystic Fibrosis Patients"

Olga KryskoThibaut Van ZeleSofie ClaeysClaus Bachert

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Comparison of the efficacy and safety of bilastine 20 mg vs desloratadine 5 mg in seasonal allergic rhinitis patients

Claus BachertP KunaF SanquerP IvanV DimitrovMM GorinaP de HeyningA Loureiro

A1 Journal Article in ALLERGY

Decreased FOXP3 protein expression in patients with asthma

Sharen ProvoostTania MaesYannick van DurmePhilippe GevaertClaus BachertC.B. Schmidt-WeberGuy BrusselleGuy JoosKurt Tournoy

A1 Journal Article in Allergy

Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization

Marie-Noelle CorriveauNan ZhangGabriële HoltappelsNadine Van RoyClaus Bachert

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY & ALLERGY

Different regulation of cigarette smoke induced inflammation in upper versus lower airways: findings from a mouse model

Wouter HuvenneClaudina Perez NovoNatalie De RuyckNele PauwelsLander RobaysTania MaesPaul Van CauwenbergeGuy JoosGuy BrusselleClaus Bachert

Differential expression of the interleukin 5 receptor alpha isoforms in blood and tissue eosinophils of nasal polyp patients

Philippe GevaertC. HellmanL. LundbladJ. LundahlGabriële HoltappelsPaul Van CauwenbergeJan TavernierClaus Bachert

A1 Journal Article in ALLERGY

Dissolution in nasal fluid, retention and anti-inflammatory activity of fluticasone furoate in human nasal tissue ex vivo

D BaumannClaus BachertP Hogger

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Effect of corticosteroids on wound healing after endoscopic sinus surgery

M JorissenClaus Bachert

A1 Journal Article in Rhinology

Efficacy and safety of bilastine 20 mg compared with cetirizine 10 mg and placebo for the symptomatic treatment of seasonal allergic rhinitis: a randomized, double-blind, parallel-group study

P KunaClaus BachertZ NowackiPaul Van CauwenbergeI AgacheL FouquertA RogerA SologurenR Valiente

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Efficacy of allergoid preparations for subcutaneous application - Evaluation of evidence in clinical studies

Claus BachertPhilippe GevaertThibaut Van Zele

A1 Journal Article in ALLERGOLOGIE

Efficacy of desloratadine in intermittent allergic rhinitis: a GA2LEN study

J BousquetClaus BachertGW CanonicaJ MullolPaul Van CauwenbergeCB JensenWJ FokkensJ RingP KeithR Lorber et al.

A1 Journal Article in ALLERGY

Enhanced release of IgE-dependent early phase mediators from nasal polyp tissue

Joke PatouGabriële HoltappelsKaren AffleckPhilippe GevaertClaudina Perez NovoPaul Van CauwenbergeClaus Bachert

A1 Journal Article in JOURNAL OF INFLAMMATION-LONDON

GA(2)LEN (Global Allergy and Asthma European Network) addresses the allergy and asthma 'epidemic'

J BousquetPG BurneyT ZuberbierPaul Van CauwenbergeCA AkdisC Bindslev-JensenS BoniniWJ FokkensF KauffmannML Kowalski et al.

A1 Journal Article in ALLERGY

GA2LEN skin test study I: GA superset of LEN harmonization of skin prick testing: novel sensitization patterns for inhalant allergens in Europe

LM HeinzerlingGJ BurbachG EdenharterClaus BachertC Bindslev-JensenS BoniniJ BousquetL Bousquet-RouanetPJ BousquetM Bresciani et al.

A1 Journal Article in ALLERGY

GA2LEN skin test study II: clinical relevance of inhalant allergen sensitizations in Europe

GJ BurbachLM HeinzerlingG EdenharterClaus BachertC Bindslev-JensenS BoniniJ BousquetL Bousquet-RouanetPJ BousquetM Bresciani et al.

A1 Journal Article in ALLERGY

GA2LEN skin test study III: Minimum battery of test inhalent allergens needed in epidemiological studies in patients

PJ BousquetG BurbachLM HeinzerlingG EdenharterClaus BachertC Bindslev-JensenS BoniniL Bousquet-RouanetP DemolyM Bresciani et al.

A1 Journal Article in ALLERGY

Human mast cells express leptin and leptin receptors

Jasmien TaildemanClaudina Perez NovoIsabelle RottiersLiesbeth FerdinandeAnouk WaeytensVeerle De ColvenaerClaus BachertPieter DemetterWim WaelputKatleen Braet et al.

A1 Journal Article in Histochemistry and Cell Biology

Impact Of Allergic Rhinitis On Asthma Control

Claus BachertE HerbotsM DramaixO Vandenplas

Important research questions in allergy and related diseases: 3-chronic rhinosinusitis and nasal polyposis - a GA(2)LEN study

Claus BachertNicholas Van BruaeneE ToskalaNan ZhangH OlzeG ScaddingCM Van DrunenJ MullolL CardellPhilippe Gevaert et al.

A1 Journal Article in ALLERGY

In Subjects with Persistent Allergic Rhinitis (PER) Treated with Desloratadine, Improvements in Total 5-Symptom Scores (T5SS) and Rhinoconjunctivitis Quality of Life Questionnaire-Standardized (RQLQ-S) Correlate with Disease Burden as Measured using a Simple Visual Analog Scale (VAS)

T ZuberbierG CanonicaClaus BachertJ Bousquet

Local Complement Activation in Nasal Polyposis

Thibaut Van ZeleFrauke CoppietersPhilippe GevaertGabriële HoltappelsPaul Van CauwenbergeClaus Bachert

A1 Journal Article in LARYNGOSCOPE

Nasal polyposis and sinusitis

Claus BachertPhilippe GevaertPaul Van Cauwenberge

Bookchapter in Middleton's Allergy: Principles and Practice

Prevalence of Self-Reported Allergic Rhinitis in Eleven Major Cities in China

L ZhangDM HanD HuangYF WuZ DongG XuWJ KongClaus Bachert

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Role of Staphylococcus Aureus Enterotoxin B in allergic sensitization

Wouter HuvenneIna CallebautJeroen VanoirbeekPaul Van CauwenbergePhilippe GevaertClaus BachertJan CeuppensPeter Hellings

TGF-beta signaling and collagen deposition in chronic rhinosinusitis

Nicholas Van BruaeneLara DeryckeClaudina Perez NovoPhilippe GevaertGabriële HoltappelsNatalie De RuyckClaude CuvelierPaul Van CauwenbergeClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The CONSORT statement checklist in allergen-specific immunotherapy: a GA2LEN paper

PJ BousquetJ BrozekClaus BachertT BieberSergio BoniniPeter BurneyM CalderonGiorgio W CanonicaE CompalatiJP Daures et al.

A1 Journal Article in ALLERGY

The effect of topical amphotericin B on inflammatory markers in patients with chronic rhinosinusitis: a multicenter randomized controlled study

Fenna A EbbensChristos GeorgalasSilvia LuitenCornelis M van DrunenLydia BadiaGlenis K ScaddingPeter W HellingsMark JorissenJoaquim MullolAlda Cardesin et al.

A1 Journal Article in LARYNGOSCOPE

The high prevalence of chronic rhinosinusitis in Europe: findings from the GA²LEN questionnaire

Wytske FokkensJurriaan KokClaus Bachert

The high prevalence of chronic rhinosinusitis in Europe: findings from the GA²LEN questionnaire

Jurriaan KokWytske FokkensClaus BachertElina ToskalaDeborah JarvisJean BousquetPeter Burney

The presence of Staphylococcus aureus is not equivalent to an immune reaction to it's enterotoxins

MN CorriveauNan ZhangClaus Bachert

A1 Journal Article in ALLERGY

Treatment of acute rhinosinusitis with the preparation from Pelargonium sidoides EPs 7630: A randomized, double-blind, placebo-controlled trial

Claus BachertA SchapowalP FunkM Kieser

A1 Journal Article in RHINOLOGY

Unmet needs in severe chronic upper airway disease (SCUAD)

Jean BousquetClaus BachertGiorgio CanonicaThomas CasaleAlvaro CruzRichard LockeyTorsten Zuberbier

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

2008

Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)

J. BousquetN. KhaltaevA. A. CruzJ. DenburgW. J. FokkensA. TogiasT. ZuberbierC. E. Baena-CagnaniG. W. CanonicaC. van Weel et al.

A1 Journal Article in ALLERGY

Association of staphylococcus aureus sentizitation with severe asthma

ML KowalskiM CieslakClaudina Perez NovoClaus Bachert

Detection of enterotoxin DNA in Staphylococcus aureus strains obtained from the middle meatus in controls and nasal polyp patients

Thibaut Van ZeleMario VaneechoutteGabriële HoltappelsPhilippe GevaertPaul Van CauwenbergeClaus Bachert

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY

Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease

Nan ZhangThibaut Van ZeleClaudina Perez NovoNicholas Van BruaeneGabriële HoltappelsNatalie De RuyckPaul Van CauwenbergeClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA(2)LEN paper

J BousquetW FokkensP BurneySR DurhamClaus BachertCA AkdisGW CanonicaSE DahlenT ZuberbierT Bieber et al.

A1 Journal Article in ALLERGY

Mepolizumab, a humanised anti-IL-5 monoclonal antibody, as treatment of severe nasal polyposis

Philippe GevaertNicholas Van BruaeneKatrien BlommeAR SOUSARP MARSHALClaus Bachert

Non-allergic perennial rhinitis

Claus BachertNicholas Van Bruaene

Bookchapter in Current Therapy

Non-allergic perennial rhinitis

Bookchapter in Scott-Brown's Otorhinolaryngology

Pilot study using doxycycline-releasing stents to ameliorate postoperative healing quality after sinus surgery

Wouter HuvenneNan ZhangE TijsmaB HissongJ HuurdemanG HoltappelsSofie ClaeysPaul Van CauwenbergeHans NelisTom Coenye et al.

A1 Journal Article in Wound Repair and Regeneration

Claus BachertC Rudack

Bookchapter in Manuale allergologikum

Role of staphylococcal superantigens in upper airway disease

Claus BachertNan ZhangJoke PatouThibaut Van ZelePhilippe Gevaert

A1 Journal Article in CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY

Rupatadine in allergic rhinitis and chronic urticaria

J. MulloJ. BousquetClaus BachertW. G. CanonicaA. Gimenez-ArnauM. L. KowalskiE. Marti-GuadanoM. MaurerC. PicadoG. Scadding et al.

A1 Journal Article in ALLERGY

Staphylococcus aureus Enterotoxin B breaks primary tolerance to ovalbumine

Wouter HuvenneI CALLEBAUTS BOBICB VERBINNENG HENSPaul Van CauwenbergePhilippe GevaertClaus BachertJ CEUPPENSP HELLINGS

Staphylococcus aureus enterotoxin B regulates prostaglandin E-2 synthesis, growth, and migration in nasal tissue fibroblasts

Claudina Perez NovoAnouk WaeytensCindy ClaeysPaul Van CauwenbergeClaus Bachert

A1 Journal Article in JOURNAL OF INFECTIOUS DISEASES

Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps

Joke PatouPhilippe GevaertThibaut Van ZeleGabriële HoltappelsPaul Van CauwenbergeClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

T-cell regulation in chronic paranasal sinus disease

Nicholas Van BruaeneClaudina Perez NovoTomasz M BasinskiThibaut Van ZeleGabriële HoltappelsNatalie De RuyckCarsten Schmidt-WeberCezmi AkdisPaul Van CauwenbergeClaus Bachert et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TGF-beta isoforms and receptors in chronic sinus disease

Nicholas Van BruaeneClaudina Perez NovoPhilippe GevaertGabriële HoltappelsNatalie De RuyckPaul Van CauwenbergeClaus Bachert

Treatment of nasal polyposis with oral methylprednisolone: a double-blind, randomized, placebo-controlled trial with evaluation of clinical and biological activity

Thibaut Van ZelePhilippe GevaertGabriële HoltappelsB AchimP WormaldS MayrG HensP HellingsF EbbenssW Fokkens et al.

2007

Anti-IgE for the treatment of allergic rhinitis - and eventually nasal polyps?

KATIA VERBRUGGENP VAN CAWENBERGEClaus Bachert

A1 Journal Article in ALLERGOLOGIE

Belgian guidelines for the treatment of acute rhinosinusitis in general practice

Claus BachertB BERTRANDJ DAELEM JORISSENP LEFEBVREP ROMBAUXB SCHMELZER

A1 Journal Article in B-ENT

Comparison of solutions for sublingual immunotherapy

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Cost-effectiveness of grass allergen tablet (GRAZAX (R)) for the prevention of seasonal grass pollen induced rhinoconjunctivitis - a Northern European perspective

Claus BachertU VESTENBAEKJ CHRISTENSENUK GRIFFITHSPB POULSEN

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Desloratadine treatment for intermittent and persistent allergic rhinitis: A review

Claus BachertPaul Van Cauwenberge

A1 Journal Article in CLINICAL THERAPEUTICS

EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity

E NIZANKOWSKA-MOGILNICKAG BOCHENEKL MASTALERZM SWIERCZYNSKAC PICADOG SCADDINGML KOWALSKIM SETKOWICZJ RINGK BROCKOW et al.

A1 Journal Article in ALLERGY

Effect of S-aureus enterotoxin B on arachidonic acid metabolism in leukocytes from patients with asthma and nasal polyps

M JEDRZEJCZAKA LEWANDOWSKA-POLAKM KOWALSKIClaudina Perez NovoClaus Bachert

Effect of mometasone furoate nasal spray on quality of life of patients with acute rhinosinusitis

Claus BachertEO MELTZER

A1 Journal Article in RHINOLOGY

Judicious antibiotic use and intranasal corticosteroids in acute rhinosinusitis

CB SMALLClaus BachertVJ LUNDA MOSCATELLOAS NAYAKWE BERGER

A1 Journal Article in AMERICAN JOURNAL OF MEDICINE

Local immunoglobulin production in nasal polyposis is modulated by superantigens

Thibaut Van ZelePhilippe GevaertGabriële HoltappelsPaul Van CauwenbergeClaus Bachert

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Long-term treatment of persistent allergic rhinitis with levocetirizine

Ludger KlimekClaus BachertG. Walter CanonicaStephen R. DurhamJoaquim MullolPaul Van CauwenbergeGenevieve Van Hammee

A1 Journal Article in ALLERGY & CLINICAL IMMUNOLOGY INTERNATIONAL-JOURNAL OF THE WORLD ALLERGY ORGANIZATION

Montelukast inhibits LTD4-TGF beta induced MMP-1 in nasal fibroblasts from chronic rhinosinusitis patients

Claudina Perez NovoCindy ClaeysPaul Van CauwenbergeClaus Bachert

Nonspecific provocation of target organs in allergic diseases: EAACI-GA(2)LEN consensus report

G RASIV BRUSASCOKH CARLSENE CRIMIT POPOVG SCHULTZE-WERNINGHAUSC GRAMICCIONIM BONINID PASSALIClaus Bachert et al.

A1 Journal Article in ALLERGY

Preclinical study of a novel, non-steroidal, plant-derived, anti-inflammatory compound for the treatment of airway disease

Philippe GevaertJoke PatouThibaut Van ZeleGabriële HoltappelsKarolien De BosscherWim Vanden BergheGuy HaegemanClaus Bachert

Present role of sublingual immunotherapy in allergic diseases

I KLEINE-TEBBEClaus BachertKC BERGMANNT BIEBERR BREHLERF FRIEDRICHST FUCHSL KLIMEKMV KOPPU LEPP et al.

Editorial material

Remodelling in nasal polyposis is independent of TH-cell polarisation

Nan ZhangTV ZELEPhilippe GevaertGabriële HoltappelsP VAN CAUWENBERGEClaus Bachert

Rhinosinusitis guidelines of the German society for otorhinolaryngology, head and neck surgery

BA STUCKClaus BachertP FEDERSPILW HOSEMANNL KLIMEKR MOSGESO PFAARC RUDACKH SITTERM WAGENMANN et al.

A1 Journal Article in HNO

Role of Staphylococcal superantigens in airway disease

Claus BachertPhilippe GevaertNan ZhangThibaut Van ZeleClaudina Perez Novo

Bookchapter in Superantigens and superallergens

Role of staphylococcal superantigens in airway disease: a review, part 2: S-aureus enterotoxins in AERD, asthma, early childhood wheezing and COPD

Claus BachertNan ZhangPhilippe GevaertThibaut Van ZeleClaudina Perez Novo

A1 Journal Article in ALLERGOLOGIE

Staphylococcal superantigens in airway disease: a review, part 1: the role of S-aureus enterotoxins in allergic rhinitis and nasal polyps

Claus BachertPhilippe GevaertNan ZhangThibaut Van ZeleClaudina Perez Novo

A1 Journal Article in ALLERGOLOGIE

Staphylococcus Aureus Enterotoxins as Immune Stimulants in Chronic Rhinosinusitis

Claus BachertNan Zhang