Research Explorer

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Researcher

Christophe Stove

Publications & Research Data

Awards & Distinctions

316 Results

2026

Determination of vitamin D and its metabolites using capillary dried blood microsampling : are we there yet?

Liesl HeughebaertRosalie GhesquièreKatleen Van UytfangheChristophe Stove

A1 Journal Article in TALANTA

2025

A f entanyl hapten-displaying lipid nanoparticle vaccine that non-covalently encapsulates a TLR7/8 agonist and T-helper epitope induces protective anti-fentanyl immunity

Zifu ZhongMarie DeventerYong ChenStijn VanheeInés LammensKim DeswarteYi HuangTingting YeHaixiu WangLutz Nuhn et al.

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cardiorespiratory effects of gamma-hydroxybutyric acid during isoflurane anaesthesia in pigs

Charlotte CuypersMathias DevreeseKatleen Van UytfangheChristophe StoveGlenn Van SteenkisteStijn Schauvliege

A1 Journal Article in VETERINARY ANAESTHESIA AND ANALGESIA

Clinical validation of a DBS-based LC-MS/MS method for 25-hydroxyvitamin D : from lab sampling to home sampling

Liesl HeughebaertRosalie GhesquièreChristophe Stove

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Comparative evaluation of approaches to convert microsampled capillary blood concentrations to plasma concentrations : paracetamol and metabolites as a case study

Laura BoffelPieter-Jan De SutterLuc De BaerdemaekerChristophe Stove

A1 Journal Article in AAPS JOURNAL

Estimation of the hematocrit in dried blood microsamples : where are we at?

Liesl HeughebaertLaura BoffelChristophe Stove

A1 Journal Article in MICROCHEMICAL JOURNAL

Folate depletion impact on the cell cycle results in restricted primary root growth in Arabidopsis

Jolien De LepeleireRatnesh MishraJana VerstraeteJosé Antonio Pedroza-GarciaChristophe StoveLieven De VeylderDominique Van Der Straeten

A1 Journal Article in PLANT MOLECULAR BIOLOGY

Identification and investigation of the intrinsic receptor activation potential and metabolization of the new Oxo-Pyridyl synthetic cannabinoid receptor agonist CH-FUBBMPDORA

Marie DeventerMaria Carmela EmanueleBrianna N. StangKatleen Van UytfangheJessica MassonXavier BouvotCatherine LamoureuxAlessandro PropositoFabiano RenieroMargaret V. Holland et al.

A1 Journal Article in DRUG TESTING AND ANALYSIS

Pharmacokinetics of paracetamol and cefazolin in children undergoing minor surgery

Anica De Smet-Van DammeChiel MolletIsis Van herteryckAnnemie BautersAlix HanetMathias DevreeseLaura BoffelChristophe StoveIngeborg DhoogeFrank Plasschaert et al.

Review on activity-based detection of doping substances and growth promotors in biological matrices : do bioassays deserve a place in control programs?

Liesl JanssensPeter Van EenooChristophe Stove

A1 Journal Article in ANALYTICA CHIMICA ACTA

Small changes, big consequences? Assessment of the impact of design changes in microsampling devices

Laura BoffelChristophe Stove

A1 Journal Article in THERAPEUTIC DRUG MONITORING

Studying paracetamol disposition in children using a minimally invasive microsampling technique : a preliminary PK analysis

Isis Van herteryckMathias DevreeseAnnemie BautersEline HermansLaura BoffelChristophe StoveP De PaepeIngeborg DhoogeFrank PlasschaertErik Van Laecke et al.

Synthesis, pharmacological characterization, and binding mode analysis of 8-hydroxy-tetrahydroisoquinolines as 5-HT7 receptor inverse agonists

Camilla B. ChanEline PottieIcaro A. SimonAdrian G. RossebøMatthias M. HerthKasper HarpsøeJesper L. KristensenChristophe StoveChristian B. M. Poulie

A1 Journal Article in ACS CHEMICAL NEUROSCIENCE

To convert or not to convert? Official International Association of Therapeutic Drug Monitoring and Clinical Toxicology guideline : considerations and recommendations for converting capillary blood microsampling concentrations to plasma concentrations

Laura BoffelHanna De BaetsLiesl HeughebaertTheo RispensAnders ÅsbergMaria ShipkovaBrenda C. M. de WinterDirk Jan A. R. MoesAnnick de VriesJan-Willem C. Alffenaar et al.

A1 Journal Article in THERAPEUTIC DRUG MONITORING

Waxy- or putty-like materials as a novel drug preparation for synthetic cannabinoid receptor agonists : petection in prisons and in vitro cannabinoid receptor activity

Axelle TimmermanMarie DeventerRachael AndrewsRobert ReidVictoria MarlandDarren EdwardsChristopher R. PudneyNiamh Nic DaéidChristophe StoveCaitlyn Norman

A1 Journal Article in DRUG TESTING AND ANALYSIS

2024

2-Substituted (N)-methanocarba A(3) adenosine receptor agonists : in silico, in vitro, and in vivo characterization

Dilip K. ToshMatteo PavanChunxia CroninEline PottieTina C. WanEric ChenSarah A. LewickiRyan G. CampbellZhan-Guo GaoJohn A. Auchampach et al.

A2 Journal Article in ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

2-Substituted (N)-methanocarba A3 adenosine receptor agonists : in silico, in vitro, and in vivo characterization

Dilip K. ToshMatteo PavanChunxia CroninEline PottieTina C. WanEric ChenSarah A. LewickiRyan G. CampbellZhan-Guo GaoJohn A. Auchampach et al.

A2 Journal Article in ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

Activity-based detection of synthetic cannabinoid receptor agonists in plant materials

Axelle TimmermanMargot BalcaenVera CoopmanMaarten DegreefEline PottieChristophe Stove

A1 Journal Article in HARM REDUCTION JOURNAL

Characterization of novel nitazene recreational drugs: Insights into their risk potential from in vitro μ-opioid receptor assays and in vivo behavioral studies in mice

Marthe VandeputteGrant C. GlatfelterDonna WaltherNathan K. LayleDanielle M. St. GermaineIstván UjváryDonna M. IulaMichael H. BaumannChristophe Stove

A1 Journal Article in PHARMACOLOGICAL RESEARCH

Comparative pharmacological effects of lisuride and lysergic acid diethylamide revisited

Grant C. GlatfelterEline PottieJohn S. PartillaChristophe StoveMichael H. Baumann

A2 Journal Article in ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

Detection in seized samples, analytical characterization, and in vitro metabolism of the newly emerged 5-bromo-indazole-3-carboxamide synthetic cannabinoid receptor agonists

Caitlyn NormanKristin WeblingOleksandra KyslychenkoRobert ReidAlex J. KrotulskiRyan FarrellMarie DeventerHuiling LiuMatthew J. ConnollyClaude Guillou et al.

A1 Journal Article in DRUG TESTING AND ANALYSIS

Detection of N-desethyl etonitazene in a drug checking sample : chemical analysis and pharmacological characterization of a recent member of the 2-benzylbenzimidazole 'nitazene' class

Manuela C. MontiLiam De VriezeMarthe VandeputteMattias PerssonHenrik GreenChristophe StoveGotz Schlotterbeck

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Elucidating the harm potential of brorphine analogues as new synthetic opioids : synthesis in vitro, and in vivo characterization

Marthe VandeputteSabrine BilelMicaela TirriGiorgia CorliMarta BassiNathan K. LayleAnna FantinatiDonna WaltherDonna M. IulaMichael H. Baumann et al.

A1 Journal Article in NEUROPHARMACOLOGY

In vitro cannabinoid activity profiling of generic ban-evading brominated synthetic cannabinoid receptor agonists and their analogs

Marie DeventerMattias PerssonCaitlyn NormanHuiling LiuMatthew J. ConnollyNiamh Nic DaéidCraig McKenzieHenrik GréenChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

In vitro cannabinoid receptor activity, metabolism, and detection in seized samples of CH-PIATA, a new indole-3-acetamide synthetic cannabinoid

Caitlyn NormanMarie DeventerOlivia DremannRobert ReidKatleen Van UytfangheClaude GuillouInge M. J. VinckierNiamh Nic DaéidAlex KrotulskiChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

In vitro characterization of protonitazene metabolites, using human liver microsomes, and first application to two urines collected from death cases

Alice AmelineLaurie GheddarSimona PichiniChristophe StoveFrederic AknoucheChristophe MaruejoulsJean-Sebastien RaulPascal Kintz

A1 Journal Article in CLINICA CHIMICA ACTA

In vitro structure-activity relationships and forensic case series of emerging 2-benzylbenzimidazole 'nitazene' opioids

Liam De VriezeSara E. WaltonEline PottieDonna PapsunBarry K. LoganAlex J. KrotulskiChristophe StoveMarthe Vandeputte

A1 Journal Article in ARCHIVES OF TOXICOLOGY

In vitro μ-opioid receptor activation potential of U10 and β-U10, positional isomers of the synthetic opioid naphthyl U-47700

Marthe VandeputteChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

Interpreting mono- and poly-SCRA intoxications from an activity-based point of view : JWH-018 equivalents in serum as a comparative measure

Liesl JanssensMichaela J. SommerKatharina Elisabeth GrafingerMaren Hermanns-ClausenVolker AuwärterChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Investigation of the intrinsic cannabinoid activity of hemp-derived and semisynthetic cannabinoids with β-arrestin2 recruitment assays-and how this matters for the harm potential of seized drugs

Liesl JanssensKatleen Van UytfangheJeffrey B. WilliamsKirk W. HeringDonna M. IulaChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Is the stability of folates in dried blood microsamples sufficient to perform home-sampling studies?

Liesl HeughebaertChristophe Stove

A1 Journal Article in ANALYST

Near-infrared-based hematocrit determination of dried blood samples collected by volumetric absorptive microsampling : an in-depth evaluation

Liesl HeughebaertLaura BoffelChristoph LührStijn LambrechtChristophe Stove

A1 Journal Article in MICROCHEMICAL JOURNAL

Nitazene test strips : a laboratory evaluation

Liam De VriezeChristophe StoveMarthe Vandeputte

A1 Journal Article in HARM REDUCTION JOURNAL

Pharmacokinetics of gamma‐hydroxybutyric acid in 6‐week‐old swine (Sus scrofa domesticus) after intravenous and oral administration

Charlotte CuypersMathias DevreeseKatleen Van UytfangheChristophe StoveStijn Schauvliege

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Pharmacokinetics of gamma‐hydroxybutyric acid in 6‐week‐old swine (Sus scrofa domesticus) after intravenous and oral administration

Charlotte CuypersMathias DevreeseKatleen Van UytfangheChristophe StoveStijn Schauvliege

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Pharmacological effects of 2-benzylbenzimidazole opioids emerging in clandestine drug markets worldwide

Michael BaumannDonna WaltherMeng-Hua TsaiLi ChenMarthe VandeputteChristophe StoveLei ShiGrant Glatfelter

Remote HbA1c testing via microsampling : fit for purpose?

Nick VerougstraeteVeronique StoveChristophe Stove

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Selective replacement of cholesterol with cationic amphiphilic drugs enables the design of lipid nanoparticles with improved RNA delivery

Bram BogaertAliona DebisschopThomas EhouarneHannelore Van EeckhoutteJoyceline De VolderAn JacobsEline PottieRiet De RyckeAurélie CrabbéPieter Mestdagh et al.

A1 Journal Article in NANO LETTERS

Self-sampling by adolescents at home : assessment of the feasibility to successfully collect blood microsamples by inexperienced individuals

Laura BoffelAnskje Van MenselJanne PauwelsElly Den HondJos BessemsKatleen Van UytfangheChristophe Stove

A1 Journal Article in AAPS JOURNAL

Simultaneous quantification of seven B vitamins from wheat grains using UHPLC-MS/MS

Da CaoLiesl HeughebaertLaura BoffelChristophe StoveDominique Van Der Straeten

A1 Journal Article in FOOD CHEMISTRY

Synthesis and functional evaluation of synthetic cannabinoid receptor agonists related to ADB-HEXINACA

Eric SparkesAxelle TimmermanJack W. MarkhamRochelle BoydRebecca GordonKatelyn A. WalkerRichard C. KevinDavid E. HibbsSamuel D. BanisterElizabeth A. Cairns et al.

A1 Journal Article in ACS CHEMICAL NEUROSCIENCE

The 'ABC' of split-nanoluciferase HIF heterodimerization bioassays : applications, Benefits & Considerations

Liesl JanssensChristophe Stove

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

The old, the new, the (un)expected : a pharmacological perspective on new synthetic opioids of the post-fentanyl analogue era

Marthe VandeputteChristophe Stove

Untargeted detection of performance-enhancing drugs : versatility of cell-based assays

Liesl JanssensChristophe StovePeter Van Eenoo

When a prophecy comes true : ethyleneoxynitazene as a 'prophetic' member of the emerging class of 2-benzylbenzimidazole 'nitazene' synthetic opioids

Marthe VandeputteGrant GlatfelterDonna WaltherIstván UjváryDonna IulaMichael BaumannChristophe Stove

2023

A protocol for a turbidimetric assay using a Saccharomyces cerevisiae thiamin biosynthesis mutant to estimate total vitamin B1 content in plant tissue samples

Simon StrobbeJana VerstraeteTeresa B. FitzpatrickChristophe StoveDominique Van Der Straeten

A1 Journal Article in PLANT METHODS

Alkoxy chain length governs the potency of 2-benzylbenzimidazole nitazene' opioids associated with human overdose

Grant C. GlatfelterMarthe VandeputteLi ChenDonna WaltherMeng-Hua M. TsaiLei ShiChristophe StoveMichael H. Baumann

A1 Journal Article in PSYCHOPHARMACOLOGY

Application of a fully automated dried blood spot method for therapeutic drug monitoring of immunosuppressants

Sigrid DeprezChristophe Stove

A1 Journal Article in ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Application of non-contact hematocrit prediction technologies to overcome hematocrit effects on immunosuppressant quantification from dried blood spots

Sigrid DeprezLiesl HeughebaertLaura BoffelChristophe Stove

A1 Journal Article in TALANTA

Assay-dependent inverse agonism at the A3 adenosine receptor : when neutral is not neutral

Eline PottieR. Rama SureshKenneth A. JacobsonChristophe Stove

A2 Journal Article in ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

Comparative neuropharmacology of structurally distinct non-fentanyl opioids that are appearing on recreational drug markets worldwide

Marthe VandeputteMeng-Hua M. TsaiLi ChenGrant C. GlatfelterDonna WaltherChristophe StoveLei ShiMichael H. Baumann

A1 Journal Article in DRUG AND ALCOHOL DEPENDENCE

Comparison of near-infrared and UV-vis-based non-contact hematocrit prediction of dried blood spots from patients on immunosuppressants

Sigrid DeprezLiesl HeughebaertLaura BoffelChristophe Stove

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Comprehensive characterization of a systematic library of alkyl and alicyclic synthetic cannabinoids related to CUMYL-PICA, CUMYL-BUTICA, CUMYL-CBMICA, and CUMYL-PINACA

Liesl JanssensAdam AmetovskiEric SparkesRochelle BoydFelcia LaiCallan J. MaloneyDane RhookRoy R. GeronaMatthew ConnollyHuiling Liu et al.

A1 Journal Article in ACS CHEMICAL NEUROSCIENCE

Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs

Marthe VandeputteSara E. WaltonSarah A. ShudaDonna M. PapsunAlex J. KrotulskiChristophe Stove

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Dual-acting small molecules : subtype-selective cannabinoid receptor 2 agonist/butyrylcholinesterase inhibitor hybrids show neuroprotection in an Alzheimer's disease mouse model

Philipp SpatzSophie A. M. SteinmüllerAnna TutovEleonora PoetaAxelle MorilleauAllison CarlesMarie DeventerJulian HofmannChristophe StoveBarbara Monti et al.

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

In vitro and in vivo evaluation of pellotine : a hypnotic lophophora alkaloid

Christian B. M. PoulieCamilla B. ChanAleksandra ParkaMagnus LettorpJosephine VosAmanda RaaschouEline PottieMikkel S. BundgaardLouis M. E. SørensenClaudia R. Cecchi et al.

A2 Journal Article in ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

In vitro characterization of the pyrazole-carrying synthetic cannabinoid receptor agonist 5F-3,5-AB-PFUPPYCA and its structural analogs

Marie DeventerCaitlyn NormanRobert ReidCraig McKenzieNiamh Nic DaeidChristophe Stove

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL

Increasing confidence in a phosphatidylethanol 16:0/18:1 cutoff at 20 ng/mL to support abstinence or minor intake of alcohol

Katleen Van UytfangheChristophe Stove

A1 Journal Article in CLINICAL CHEMISTRY

Liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring of immunosuppressants and creatinine from a single dried blood spot using the Capitainer® qDBS device

Sigrid DeprezKatleen Van UytfangheChristophe Stove

A1 Journal Article in ANALYTICA CHIMICA ACTA

Microsampling at home : a patient-centric approach to monitor cancer therapy and diabetes

Nick VerougstraeteChristophe StoveVeronique StoveAlain Verstraete

Off-target activity of NBOMes and NBOMe analogs at the mu opioid receptor

Marie DeventerMattias PerssonAntonio LausEline PottieAnnelies CannaertGraziella ToccoHenrik GreenChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Pharmacodynamics of 250 mg/kg gamma hydroxy butyric acid (GHB) administered intravenously in 6 pigs undergoing general anesthesia

Charlotte CuypersMathias DevreeseKatleen Van UytfangheChristophe StoveGlenn Van SteenkisteStijn Schauvliege

Structure-activity assessment and in-depth analysis of biased agonism in a set of phenylalkylamine 5‑HT2A receptor agonists

Eline PottieChristian B. M. PoulieIcaro A. SimonKasper HarpsøeLaura D'AndreaIgor V. KomarovDavid E. GloriamAnders A. JensenJesper L. KristensenChristophe Stove

A1 Journal Article in ACS CHEMICAL NEUROSCIENCE

Untargeted detection of HIF stabilizers in doping samples : activity-based screening with a stable in vitro bioassay

Liesl JanssensLaurie De WildePeter Van EenooChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

Visible-light photoswitchable benzimidazole azo-arenes as β-arrestin2-biased selective cannabinoid 2 receptor agonists

Sophie A. M. SteinmüllerJulia FenderMarie DeventerAnna TutovKristina LorenzChristophe StoveJames N. HislopMichael Decker

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2022

A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs

Bram BogaertFelix SauvageRoberta GuagliardoCristina Muntean[missing] Van Phuc NguyenEline PottieMike WelsAn-Katrien MinnaertRiet De RyckeQiangbing Yang et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

A new cannabinoid receptor 1 selective agonist evading the 2021 'China ban': ADB‐FUBIATA

Marie DeventerKatleen Van UytfangheInge M. J. VinckierFabiano RenieroClaude GuillouChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

A novel panel of yeast assays for the assessment of thiamin and its biosynthetic intermediates in plant tissues

Simon StrobbeJana VerstraeteTeresa B. FitzpatrickMaria FaustinoTiago F. LourençoM. Margarida OliveiraChristophe StoveDominique Van Der Straeten

A1 Journal Article in NEW PHYTOLOGIST

A(3) adenosine receptor agonists containing dopamine moieties for enhanced interspecies affinity

Dilip K. ToshVeronica SalmasoRyan G. CampbellHarsha RaoAmelia BitantEline PottieChristophe StoveNaili LiuOksana GavrilovaZhan-Guo Gao et al.

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

An enlightening trip through psychedelic and purinergic signaling

Eline PottieChristophe Stove

Analytical performance of eight enzymatic assays for ethanol in serum evaluated by data from the Belgian external quality assessment scheme

Wim CouckeCorinne CharlierKathleen CroesBoris MahieuHugo NeelsChristophe StoveJan TytgatAndre VanescoteAlain VerstraeteSarah Wille et al.

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Application of a volumetric absorptive microsampling (VAMS)-based method for the determination of paracetamol and four of its metabolites as a tool for pharmacokinetic studies in obese and non-obese patients

Laura BoffelLisa DelahayeLuc De BaerdemaekerChristophe Stove

A1 Journal Article in CLINICAL PHARMACOKINETICS

Are the N-demethylated metabolites of U-47700 more active than their parent compound? In vitro mu-opioid receptor activation of N-desmethyl-U-47700 and N,N-bisdesmethyl-U-47700

Frederike NordmeierAnnelies CannaertChristophe StovePeter H. SchmidtMarkus R. MeyerNadine Schaefer

A1 Journal Article in DRUG TESTING AND ANALYSIS

Cannabinoid receptor activation potential of the next generation, generic ban evading OXIZID synthetic cannabinoid receptor agonists

Marie DeventerKatleen Van UytfangheInge M. J. VinckierFabiano RenieroClaude GuillouChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

Characterization of recent non-fentanyl synthetic opioids via three different in vitro mu-opioid receptor activation assays

Marthe VandeputteMattias PerssonDonna WaltherSvante VikingssonRobert KronstrandMichael H. BaumannHenrik GreenChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Consensus for the use of the alcohol biomarker phosphatidylethanol (PEth) for the assessment of abstinence and alcohol consumption in clinical and forensic practice (2022 Consensus of Basel)

Marc LuginbuhlFriedrich M. WurstFrederike StothWolfgang WeinmannChristophe StoveKatleen Van Uytfanghe

A1 Journal Article in DRUG TESTING AND ANALYSIS

Cov²MS : an automated and quantitative matrix-independent assay for mass spectrometric measurement of SARS-CoV-2 nucleocapsid protein

Bart Van PuyveldeKatleen Van UytfangheLaurence Van OudenhoveRalf GabrielsTessa Van RoyenArne MatthysMorteza RazaviRichard YipTerry PearsonNicolas Drouin et al.

A1 Journal Article in ANALYTICAL CHEMISTRY

Current evolutions, applications, and challenges of phosphatidylethanol analysis for clinical and forensic purposes

Marc LuginbühlKatleen Van UytfangheFrederike StöthFriedrich M. WurstChristophe Stove

A2 Journal Article in WIRES FORENSIC SCIENCE

Development of an indole-amide-based photoswitchable cannabinoid receptor subtype 1 (CB1R) 'Cis-On' Agonist

Diego A. Rodríguez-SoachaSophie A. M. SteinmüllerAli IşbilirJulia FenderMarie DeventerYesid A. RamírezAnna TutovChristoph SotrifferChristophe StoveKristina Lorenz et al.

A1 Journal Article in ACS CHEMICAL NEUROSCIENCE

Discovery of ss-arrestin-biased 25CN-NBOH-derived 5-HT2A receptor agonists

Christian B. M. PoulieEline PottieIcaro A. SimonKasper HarpsoeLaura D'AndreaIgor V. KomarovDavid E. GloriamAnders A. JensenChristophe StoveJesper L. Kristensen

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Dried blood spots for immunosuppressant drug monitoring : towards a more patient-centric follow-up

Sigrid DeprezChristophe StoveAlain VerstraeteVeronique Stove

Enlightening the 'spirit molecule' : photomodulation of the 5-HT2A receptor by a light-controllable N,N-dimethyltryptamine derivative

Hubert GerweFeng HeEline PottieChristophe StoveMichael Decker

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

First identification, chemical analysis and pharmacological characterization of N-piperidinyl etonitazene (etonitazepipne), a recent addition to the 2-benzylbenzimidazole opioid subclass

Marthe VandeputteNick VerougstraeteDonna WaltherGrant C. GlatfelterJeroen MalflietMichael H. BaumannAlain VerstraeteChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

In vitro assays for the functional characterization of (psychedelic) substances at the serotonin receptor 5-HT2AR

Eline PottieChristophe Stove

A1 Journal Article in JOURNAL OF NEUROCHEMISTRY

In vitro functional assays as a tool to study new synthetic opioids at the mu-opioid receptor : potential, pitfalls and progress

Marthe VandeputteLakshmi VasudevanChristophe Stove

A1 Journal Article in PHARMACOLOGY & THERAPEUTICS

In-depth evaluation of automated non-contact reflectance-based hematocrit prediction of dried blood spots

Laura BoffelLiesl HeughebaertStijn LambrechtMarc LuginbuehlChristophe Stove

A1 Journal Article in ANALYST

Linking in vitro and ex vivo CB1 activity with serum concentrations and clinical features in 5F-MDMB-PICA users to better understand SCRAs and their metabolites

Liesl JanssensSimon HudsonDavid M. WoodCaitlin WolfePaul I. DarganChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Machine learning to assist in large-scale, activity-based synthetic cannabinoid receptor agonist screening of serum samples

Liesl JanssensDimitri BoeckaertsSimon HudsonDaria MorozovaAnnelies CannaertDavid M. WoodCaitlin WolfeBernard De BaetsMichiel StockPaul, I Dargan et al.

A1 Journal Article in CLINICAL CHEMISTRY

Monitoring the use of alcohol-A critical overview of the state-of-the-art biomarkers

Katleen Van UytfangheEvy De BoosereChristophe Stove

A2 Journal Article in WILEY INTERDISCIPLINARY REVIEWS: FORENSIC SCIENCE

Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole 'nitazene' synthetic opioid

Marthe VandeputteAlex J. KrotulskiDonna WaltherGrant C. GlatfelterDonna PapsunSara E. WaltonBarry K. LoganMichael H. BaumannChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Phenethyl-4-ANPP : a marginally active byproduct suggesting a switch in illicit fentanyl synthesis routes

Marthe VandeputteAlex J. KrotulskiFabian HulpiaSerge Van CalenberghChristophe Stove

A1 Journal Article in JOURNAL OF ANALYTICAL TOXICOLOGY

Promising tools to facilitate the implementation of TDM of biologics in clinical practice

Rani SoenenChristophe StoveAlessio CapobiancoHanne De SchutterMarie DobbelaereTahmina MahjorMerel FollensJo LambertLynda Grine

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

Set‐up of a population‐based model to verify alcohol abstinence via monitoring of the direct alcohol marker phosphatidylethanol 16:0/18:1

Katleen Van UytfangheLiesl HeughebaertEmmanuel AbatihChristophe Stove

A1 Journal Article in ADDICTION

Structure-activity relationships of valine, tert-leucine, and phenylalanine amino acid-derived synthetic cannabinoid receptor agonists related to ADB-BUTINACA, APP-BUTINACA, and ADB-P7AICA

Eric SparkesElizabeth A. CairnsRichard C. KevinFelcia LaiKatharina Elisabeth GrafingerShuli ChenMarie DeventerRoss EllisonRochelle BoydLewis J. Martin et al.

A1 Journal Article in RSC MEDICINAL CHEMISTRY

The P2Y(2) receptor C-terminal tail modulates but is dispensable for beta-arrestin recruitment

Eline PottieJolien StormeChristophe Stove

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The rise and fall of isotonitazene and brorphine : two recent stars in the synthetic opioid firmament

Marthe VandeputteAlex J. KrotulskiDonna M. PapsunBarry K. LoganChristophe Stove

A1 Journal Article in JOURNAL OF ANALYTICAL TOXICOLOGY

Therapeutic drug monitoring of tyrosine kinase inhibitors using dried blood microsamples

Nick VerougstraeteVeronique StoveAlain VerstraeteChristophe Stove

A1 Journal Article in FRONTIERS IN ONCOLOGY

Toxicological and pharmacological characterization of novel cinnamylpiperazine synthetic opioids in humans and in vitro including 2-methyl AP-237 and AP-238

Melissa F. FogartyMarthe VandeputteAlex J. KrotulskiDonna PapsunSara E. WaltonChristophe StoveBarry K. Logan

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Volumetric absorptive microsampling as a suitable tool to monitor tyrosine kinase inhibitors

Nick VerougstraeteChristophe Stove

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

2021

Alternative sampling devices to collect dried blood microsamples : state-of-the-art

Lisa DelahayeHerman VeenhofBirgit C. P. KochJan-Willem C. AlffenaarRafael LindenChristophe Stove

A1 Journal Article in THERAPEUTIC DRUG MONITORING

Alternative sampling strategies in therapeutic drug monitoring : microsampling growing toward maturity

Lisa DelahayeChristophe Stove

An optimized LC-MS/MS method as a pivotal tool to steer thiamine biofortification strategies in rice

Jana VerstraeteSimon StrobbeDominique Van Der StraetenChristophe Stove

A1 Journal Article in TALANTA

Barriers and opportunities for the clinical implementation of therapeutic drug monitoring in oncology

Bradley D. MenzSophie L. StockerNick VerougstraeteDanijela KocicPeter GalettisChristophe StoveStephanie E. Reuter

A1 Journal Article in BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Cov-MS : a community-based template assay for mass-spectrometry-based protein detection in SARS-CoV-2 patients

Bart Van PuyveldeKatleen Van UytfangheOlivier TytgatLaurence Van OudenhoveRalf GabrielsRobbin BouwmeesterSimon DaledTim Van Den BosschePathmanaban RamasamySigrid Verhelst et al.

A2 Journal Article in JACS AU

Determination of paracetamol and its metabolites via LC-MS/MS in dried blood volumetric absorptive microsamples : a tool for pharmacokinetic studies

Lisa DelahayeLuc De BaerdemaekerChristophe Stove

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Diagnosing intake and rationalizing toxicities associated with 5F-MDMB-PINACA and 4F-MDMB-BINACA abuse

Wen LieEleanor Jing Yi CheongEvelyn Mei Ling GohHooi Yan MoyAnnelies CannaertChristophe StoveEric Chun Yong Chan

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Fully automated dried blood spot extraction coupled to liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring of immunosuppressants

Sigrid DeprezChristophe Stove

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Metabolic engineering of rice endosperm towards higher vitamin B1 accumulation

Simon StrobbeJana VerstraeteChristophe StoveDominique Van Der Straeten

A1 Journal Article in PLANT BIOTECHNOLOGY JOURNAL

Metabolic engineering provides insight into the regulation of thiamin biosynthesis in plants

Simon StrobbeJana VerstraeteChristophe StoveDominique Van Der Straeten

A1 Journal Article in PLANT PHYSIOLOGY

Near-infrared-based hematocrit prediction of dried blood spots : an in-depth evaluation

Lisa DelahayeLiesl HeughebaertChristoph LuhrStijn LambrechtChristophe Stove

A1 Journal Article in CLINICA CHIMICA ACTA

NNL-3 : a synthetic intermediate or a new class of hydroxybenzotriazole esters with cannabinoid receptor activity?

Adam AmetovskiElizabeth A. CairnsKatharina Elisabeth GrafingerAnnelies CannaertMarie DeventerShuli ChenXinyi WuCaitlin E. SheppersonFelcia LaiRoss Ellison et al.

A1 Journal Article in ACS CHEMICAL NEUROSCIENCE

Obituary Peter Blanckaert

Christophe Stove

Patient-centric assessment of thiamine status in dried blood volumetric absorptive microsamples using LC-MS/MS analysis

Jana VerstraeteChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

Patient-centric microsampling strategies : towards resolving the pain(s)

Lisa DelahayeChristophe Stove

Porphyrins produced by acneic Cutibacterium acnes strains activate the inflammasome by inducing K+ leakage

Karl-Jan SpittaelsKatleen Van UytfangheChristos C. ZouboulisChristophe StoveAurélie CrabbéTom Coenye

A1 Journal Article in ISCIENCE

Quantification of eight hematological tyrosine kinase inhibitors in both plasma and whole blood by a validated LC-MS/MS method

Nick VerougstraeteVeronique StoveAlain VerstraeteChristophe Stove

A1 Journal Article in TALANTA

Quantitation of phosphatidylethanol in dried blood after volumetric absorptive microsampling

Katleen Van UytfangheMaria del Mar Ramirez FernandezAurelie De VosSarah M. R. WilleChristophe Stove

A1 Journal Article in TALANTA

Receptor density influences ligand-induced dopamine D2L receptor homodimerization

Mattia FerraioloHicham AtikRomane PonthotInes Belo do NascimentoPauline BeckersChristophe StoveEmmanuel Hermans

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACOLOGY

Report on a new opioid NPS : chemical and in vitro functional characterization of a structural isomer of the MT-45 derivative diphenpipenol

Annelies CannaertFabian HulpiaMartijn RisseeuwKatleen Van UytfangheEric DeconinckSerge Van CalenberghPeter BlanckaertChristophe Stove

A1 Journal Article in JOURNAL OF ANALYTICAL TOXICOLOGY

Self-sampling at home using volumetric absorptive microsampling : coupling analytical evaluation to volunteers’ perception in the context of a large scale study

Katleen Van UytfangheLiesl HeughebaertChristophe Stove

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Sensing an oxygen sensor : development and application of activity-based assays directly monitoring HIF heterodimerization

Liesl JanssensChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

Serotonin 2A receptor (5-HT2AR) activation by 25H-NBOMe positional isomers : in vitro functional evaluation and molecular docking

Eline PottieOlga V. KupriyanovaAsher L. BrandtRobert B. LaprairieVadim A. ShevyrinChristophe Stove

A2 Journal Article in ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

Shape matters : the application of activity-based in vitro bioassays and chiral profiling to the pharmacological evaluation of synthetic cannabinoid receptor agonists in drug-infused papers seized in prisons

Lysbeth H. AntonidesAnnelies CannaertCaitlyn NormanNiamh NicDaeidOliver B. SutcliffeChristophe StoveCraig McKenzie

A1 Journal Article in DRUG TESTING AND ANALYSIS

Simultaneous readout of multiple FRET pairs using photochromism

Thijs RoebroekWim VandenbergFrancois SipieterSiewert HugelierChristophe StoveJin ZhangPeter Dedecker

A1 Journal Article in NATURE COMMUNICATIONS

Synthesis and functional characterization of 2-(2,5-dimethoxyphenyl)-N-(2-fluorobenzyl)ethanamine (25H-NBF) positional isomers

Eline PottieOlga V KupriyanovaVadim A. ShevyrinChristophe Stove

A1 Journal Article in ACS CHEMICAL NEUROSCIENCE

Synthesis, chemical characterization, and mu-opioid receptor activity assessment of the emerging group of 'nitazene' 2-benzylbenzimidazole synthetic opioids

Marthe VandeputteKatleen Van UytfangheNathan LayleDanielle St GermaineDonna IulaChristophe Stove

A1 Journal Article in ACS CHEMICAL NEUROSCIENCE

Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB-4en-PICA, MDMB-4en-PINACA, ADB-4en-PINACA, and MMB-4CN-BUTINACA using a combination of binding and different CB1 receptor activation assays : part III : The G protein pathway and critical comparison of different assays

Katharina Elisabeth GrafingerMarthe VandeputteAnnelies CannaertAdam AmetovskiEric SparkesElizabeth CairnsPatrick Osamu JuchliBelal HaschimiBenedikt PulverSamuel D. Banister et al.

A1 Journal Article in DRUG TESTING AND ANALYSIS

Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB-4en-PICA, MDMB-4en-PINACA, ADB-4en-PINACA, and MMB-4CN-BUTINACA using a combination of binding and different CB1 receptor activation assays-Part II: Structure activity relationship assessment via a beta-arrestin recruitment assay

Katharina GrafingerAnnelies CannaertAdam AmetovskiEric SparkesElizabeth CairnsSamuel D. BanisterVolker AuwarterChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB-4en-PICA, MDMB-4en-PINACA, ADB-4en-PINACA, and MMB-4CN-BUTINACA using a combination of binding and different CB1 receptor activation assays: Part I-Synthesis, analytical characterization, and binding affinity for human CB1 receptors

Edward PikeKatharina GrafingerAnnelies CannaertAdam AmetovskiJia Lin LuoEric SparkesElizabeth A. CairnsRoss EllisonRoy GeronaChristophe Stove et al.

A1 Journal Article in DRUG TESTING AND ANALYSIS

The balance of MU-opioid, dopamine D2 and adenosine A2A heteroreceptor complexes in the ventral striatal-pallidal GABA antireward neurons may have a significant role in morphine and cocaine use disorders

Dasiel O. Borroto-EscuelaKarolina WydraRamon Fores-PonsLakshmi VasudevanWilber Romero-FernandezMalgorzata FrankowskaLuca FerraroSarah BeggiatoMinerva Crespo-RamirezAlicia Rivera et al.

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

The next generation of synthetic cannabinoids : detection, activity, and potential toxicity of pent-4en and but-3en analogues including MDMB-4en-PINACA

Alex J. KrotulskiAnnelies CannaertChristophe StoveBarry K. Logan

A1 Journal Article in DRUG TESTING AND ANALYSIS

Vitamin B1 monitoring : a micronutrient with MACRO challenges

Jana VerstraeteChristophe StoveDominique Van Der Straeten

Volumetric absorptive microsampling (VAMS) as a reliable tool to assess thiamine status in dried blood microsamples : a comparative study

Jana VerstraeteChristophe Stove

A1 Journal Article in AMERICAN JOURNAL OF CLINICAL NUTRITION

Volumetric absorptive microsampling as an alternative tool for biomonitoring of multi-mycotoxin exposure in resource-limited areas

Arnau Vidal CorominasLidia BelovaChristophe StoveMarthe De BoevreSarah De Saeger

A1 Journal Article in TOXINS

2020

A novel nanobody-based bio-assay using functional complementation of a split nanoluciferase to monitor Mu- opioid receptor activation

Lakshmi VasudevanChristophe Stove

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Assessment of biased agonism among distinct synthetic cannabinoid receptor agonist scaffolds

Elise WoutersJolien WalraedMichael Joseph RobertsonMax MeyrathMartyna SzpakowskaAndy ChevignéGeorgios SkiniotisChristophe Stove

A2 Journal Article in ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

Assessment of biased agonism at the A(3) adenosine receptor using beta-arrestin and miniG alpha(i) recruitment assays

Eline PottieDilip K. ToshZhan-Guo GaoKenneth A. JacobsonChristophe Stove

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

Assessment of structure-activity relationships and biased agonism at the Mu opioid receptor of novel synthetic opioids using a novel, stable bio-assay platform

Lakshmi VasudevanMarthe VandeputteMarie DeventerElise WoutersAnnelies CannaertChristophe Stove

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

CNS disorders validation and application of methods for GPCR expression and interactions

René CransChristophe StoveFrancisco Ciruela

Comment on HbA(1c) determination from HemaSpot blood collection devices : comparison of home-prepared dried blood spots with standard venous blood analysis

Nick VerougstraeteVeronique StoveChristophe Stove

A1 Journal Article in DIABETIC MEDICINE

Development, validation and application of an inductively coupled plasma mass spectrometry method to determine cobalt in metal-on-metal prosthesis patients using volumetric absorptive microsampling

Sara CapiauEduardo Bolea FernandezLieve BalcaenCatherine Van Der StraetenAlain VerstraeteFrank VanhaeckeChristophe Stove

A1 Journal Article in TALANTA

Dried blood microsample-assisted determination of vitamins : recent developments and challenges

Jana VerstraeteLaura BoffelChristophe Stove

A1 Journal Article in TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Dried blood microsamples : suitable as an alternative matrix for the quantification of paracetamol-protein adducts?

Lisa DelahayeEvelyn DhontPieter De CockPeter De PaepeChristophe Stove

A1 Journal Article in TOXICOLOGY LETTERS

Dried blood microsampling-based therapeutic drug monitoring of antiepileptic drugs in children with nodding syndrome and epilepsy in Uganda and the Democratic Republic of the Congo

Sofie VelgheLisa DelahayeRodney OgwangAn HotterbeekxRobert ColebundersMichel MandroRichard IdroChristophe Stove

A1 Journal Article in THERAPEUTIC DRUG MONITORING

Evidence of enzyme-mediated transesterification of synthetic cannabinoids with ethanol : potential toxicological impact

Orapan ApirakkanIvana GavrilovicGiuseppe FlorestaCheyanne PierreAnnelies CannaertChristophe StovePaul I DarganDavid A CowanLewis CouchmanVincenzo Abbate

A1 Journal Article in FORENSIC TOXICOLOGY

First report on brorphine : the next opioid on the deadly new psychoactive substance horizon?

Nick VerougstraeteMarthe VandeputteCathelijne LyphoutAnnelies CannaertFabian HulpiaSerge Van CalenberghAlain VerstraeteChristophe Stove

A1 Journal Article in JOURNAL OF ANALYTICAL TOXICOLOGY

Folate control of plant development : from an in depth fundamental exploration towards biotech-based applications in human nutrition

Jolien De LepeleireDominique Van Der StraetenChristophe Stove

Hematocrit prediction in volumetric absorptive microsamples

Sara CapiauChristophe Stove

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Identification of psychedelic new psychoactive substances (NPS) showing biased agonism at the 5-HT2AR through simultaneous use of beta-arrestin 2 and miniG alpha(q) bioassays

Eline PottiePeter DedeckerChristophe Stove

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

In vitro activity profiling of Cumyl-PEGACLONE variants at the CB1 receptor : fluorination versus isomer exploration

Liesl JanssensAnnelies CannaertMatthew J. ConnollyHuiling LiuChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

In vitro functional characterization of a panel of non-fentanyl opioid new psychoactive substances

Marthe VandeputteAnnelies CannaertChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

In vitro structure-activity relationship determination of 30 psychedelic new psychoactive substances by means of beta-arrestin 2 recruitment to the serotonin 2A receptor

Eline PottieAnnelies CannaertChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Kainic acid-induced status epilepticus decreases mGlu5 receptor and phase-specifically downregulates Homer1b/c expression

René CransSofie DaelemansRobrecht RaedtFrancisco CiruelaChristophe Stove

A1 Journal Article in BRAIN RESEARCH

Recent developments in electrochemical detection of illicit drugs in diverse matrices

Esther De RyckeChristophe StovePeter DubruelSarah De SaegerNatalia Beloglazova

A1 Journal Article in BIOSENSORS & BIOELECTRONICS

Report on a novel emerging class of highly potent benzimidazole NPS opioids : chemical and in vitro functional characterization of isotonitazene

Peter BlanckaertAnnelies CannaertKatleen Van UytfangheFabian HulpiaEric DeconinckSerge Van CalenberghChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

Semiquantitative activity-based detection of JWH-018, a synthetic cannabinoid receptor agonist, in oral fluid after vaping

Annelies CannaertMaria del Mar Ramirez FernandezEef L. TheunissenJohannes G. RamaekersSarah WilleChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

Striatal dopamine D-2-Muscarinic Acetylcholine M-1 Receptor-Receptor interaction in a model of movement disorders

René CransElise WoutersMarta Valle-LeonJaume TauraCaio M. MassariVictor Fernandez-DuenasChristophe StoveFrancisco Ciruela

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Synthesis and in vitro cannabinoid receptor 1 activity of recently detected synthetic cannabinoids 4F-MDMB-BICA, 5F-MPP-PICA, MMB-4en-PICA, CUMYL-CBMICA, ADB-BINACA, APP-BINACA, 4F-MDMB-BINACA, MDMB-4en-PINACA, A-CHMINACA, 5F-AB-P7AICA, 5F-MDMB-P7AICA, and 5F-AP7AICA

Annelies CannaertEric SparkesEdward PikeJia Lin LuoAda FangRichard C. KevinRoss EllisonRoy GeronaSamuel D. BanisterChristophe Stove

A1 Journal Article in ACS CHEMICAL NEUROSCIENCE

The first comprehensive LC–MS/MS method allowing dissection of the thiamine pathway in plants

Jana VerstraeteSimon StrobbeDominique Van Der StraetenChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

Toxicokinetics and toxicodynamics of the fentanyl homologs cyclopropanoyl-1-benzyl-4 '-fluoro-4-anilinopiperidine and furanoyl-1-benzyl-4-anilinopiperidine

Tanja M. GampferLea WagmannYu Mi ParkAnnelies CannaertJennifer HerrmannSvenja FischmannFolker WestphalRolf MuellerChristophe StoveMarkus R. Meyer

A1 Journal Article in ARCHIVES OF TOXICOLOGY

2019

Activity-based reporter assays for the screening of abused substances in biological matrices

Annelies CannaertMarthe VandeputteSarah WilleChristophe Stove

A1 Journal Article in CRITICAL REVIEWS IN TOXICOLOGY

Application of an activity-based receptor bioassay to investigate the in vitro activity of selected indole- and indazole-3-carboxamide-based synthetic cannabinoids at CB1 and CB2 receptors

Carolina NobleAnnelies CannaertKristian LinnetChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

Clinical determination of folates : recent analytical strategies and challenges

Jana VerstraeteFilip KiekensSimon StrobbeHans De SteurXavier GellynckDominique Van Der StraetenChristophe Stove

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Comprehensive investigation on synthetic cannabinoids : metabolic behavior and potency testing, using 5F-APP-PICA and AMB-FUBINACA as model compounds

David Fabregat-SafontMarie MardalCarolina NobleAnnelies CannaertChristophe StoveJuan V SanchoKristian LinnetFelix HernandezMaria Ibanez

A1 Journal Article in DRUG TESTING AND ANALYSIS

Distinct dopamine D2 receptor antagonists differentially impact D2 receptor oligomerization

Elise WoutersAdrián Ricarte MarínJames Andrew Rupert DaltonJesús GiraldoChristophe Stove

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dried blood spots in toxicology : towards new insights and new applications

Sara CapiauChristophe StoveAlain VerstraeteVeronique Stove

Editorial: Advances in Analytical Methods for Drugs of Abuse Testing

Shanlin FuChristophe StoveSimon Elliott

Editorial material

Enantiospecific synthesis, chiral separation, and biological activity of four indazole-3-carboxamide-type synthetic cannabinoid receptor agonists and their detection in seized drug samples

Lysbeth H AntonidesAnnelies CannaertCaitlyn NormanLoelia VivesAidan HarrisonAndrew CostelloNiamh Nic DaeidChristophe StoveOliver B SutcliffeCraig McKenzie

A1 Journal Article in FRONTIERS IN CHEMISTRY

Evaluating the applicability of mouse SINEs as an alternative normalization approach for RT-qPCR in brain tissue of the APP23 model for Alzheimer’s disease

Jana JanssensRené CransKathleen Van CraenenbroeckJo VandesompeleChristophe StoveDebby Van DamPeter P. De Deyn

A1 Journal Article in JOURNAL OF NEUROSCIENCE METHODS

Evaluation of the performance and hematocrit independence of the HemaPEN as a volumetric dried blood spot collection device

Sigrid DeprezLucia Paniagua-GonzalezSofie VelgheChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

From heterodimerization to new synthetic opioids : there is MORe than meets the eye in Mu Opioid Receptor signaling

Lakshmi VasudevanChristophe StoveDeepak K Saini

Fully automated therapeutic drug monitoring of anti-epileptic drugs making use of dried blood spots

Sofie VelgheSigrid DeprezChristophe Stove

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Functional evaluation of carboxy metabolites of synthetic cannabinoid receptor agonists featuring scaffolds based on L‐valine or L‐tert ‐leucine

Elise WoutersLukas MoglerAnnelies CannaertVolker AuwärterChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

Heterodimerization of mu opioid receptor protomer with dopamine D2 receptor modulates agonist-induced internalization of mu opioid receptor

Lakshmi VasudevanDasiel O Borroto-EscuelaJelle HuysentruytKjell FuxeDeepak K SainiChristophe Stove

A1 Journal Article in BIOMOLECULES

Hide and seek : overcoming the masking effect of opioid antagonists in activity-based screening tests

Annelies CannaertMarie DeventerMelissa FogartyAmanda LA MohrChristophe Stove

A1 Journal Article in CLINICAL CHEMISTRY

Insights into biased signaling at cannabinoid receptors : synthetic cannabinoid receptor agonists

Elise WoutersJolien WalraedSamuel D. BanisterChristophe Stove

Editorial material

Is the hematocrit still an issue in quantitative dried blood spot analysis?

Sofie VelgheLisa DelahayeChristophe Stove

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Luminescence- and fluorescence-based complementation assays to screen for GPCR oligomerization : current state of the art

Elise WoutersLakshmi VasudevanRené CransDeepak K SainiChristophe Stove

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Official international association for therapeutic drug monitoring and clinical toxicology guideline : development and validation of dried blood spot-based methods for therapeutic drug monitoring

Sara CapiauHerman VeenhofRemco A. KosterYngve BergqvistMichael BoettcherOtto HalminghBrian G. KeevilBirgit C.P. KochRafael LindenConstantinos Pistos et al.

A1 Journal Article in THERAPEUTIC DRUG MONITORING

Quantification of cocaine and cocaine metabolites in dried blood spots from a controlled administration study using liquid chromatography-tandem mass spectrometry

Lars AmbachEleanor MenziesMark C ParkinAndrew KicmanJohn RH ArcherDavid M WoodPaul I DarganChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

Setup of a serotonin 2A receptor (5-HT2AR) bioassay : demonstration of its applicability to functionally characterize hallucinogenic new psychoactive substances and an explanation why 5-HT2AR bioassays are not suited for universal activity-based screening of biofluids for new psychoactive substances

Eline PottieAnnelies CannaertKatleen Van UytfangheChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

The validation of Short Interspersed Nuclear Elements (SINEs) as a RT-qPCR normalization strategy in a rodent model for temporal lobe epilepsy

René CransJana JanssensSofie DaelemansElise WoutersRobrecht RaedtDebby Van DamPeter P De DeynKathleen Van CraenenbroeckChristophe Stove

A1 Journal Article in PLOS ONE

Therapeutic drug monitoring in the dried spotlight

Sofie VelgheChristophe Stove

Validation of activity-based screening for synthetic cannabinoid receptor agonists in a large set of serum samples

Annelies CannaertMarthe VandeputteSimon HudsonDavid M WoodPaul I DarganChristophe Stove

A1 Journal Article in CLINICAL CHEMISTRY

Vitamin metabolism in plants : from B-Vitamin biology towards crop biofortification

Simon StrobbeDominique Van Der StraetenChristophe Stove

Volumetric absorptive microsampling as an alternative sampling strategy for the determination of paracetamol in blood and cerebrospinal fluid

Lisa DelahayeEvelyn DhontPieter De CockPeter De PaepeChristophe Stove

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Whether it is the action of dopamine or dope : it is all about interaction

Elise WoutersChristophe Stove

2018

Activity-based concept to screen biological matrices for opiates and (synthetic) opioids

Annelies CannaertLakshmi VasudevanMelissa FrisciaAmanda LA MohrSarah MR WilleChristophe Stove

A1 Journal Article in CLINICAL CHEMISTRY

Activity-based detection and bioanalytical confirmation of a fatal carfentanil intoxication

Annelies CannaertLars AmbachPeter BlanckaertChristophe Stove

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Activity-based detection of cannabinoids in serum and plasma samples

Annelies CannaertJolien StormeCornelius HessVolker AuwärterSarah MR WilleChristophe Stove

A1 Journal Article in CLINICAL CHEMISTRY

Activity-based detection of new psychoactive substances as an alternative screening approach in forensic toxicology

Annelies CannaertChristophe StoveSarah Wille

Assessing GPCR dimerization in living cells : comparison of the NanoBiT assay with related bioluminescence- and fluorescence-based approaches

Elise WoutersLakshmi VasudevanFrancisco CiruelaDeepak SainiChristophe StoveKathleen Van Craenenbroeck

Bookchapter in Receptor-receptor interactions in the central nervous system

Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics : a systematic review

Yarmarly C Guerra ValeroSteven C WallisJeffrey LipmanChristophe StoveJason A RobertsSuzanne L Parker

A1 Journal Article in BIOANALYSIS

Correction for the hematocrit bias in dried blood spot analysis using a nondestructive, single-wavelength reflectance-based hematocrit prediction method

Sara CapiauLeah S WilkPieter De KeselMaurice CG AaldersChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

Design, synthesis, and biological evaluation of bivalent ligands targeting dopamine D2-like receptors and the μ-opioid receptor

Mingcheng QianLakshmi VasudevanJelle HuysentruytMartijn RisseeuwChristophe StovePatrick ML VanderheydenKathleen Van CraenenbroeckSerge Van Calenbergh

A1 Journal Article in CHEMMEDCHEM

Dried blood spots in therapeutic drug monitoring and toxicology

Sofie VelgheRani De TroyerChristophe Stove

Editorial material

Evaluation of the Capitainer-B microfluidic device as a new hematocrit-independent alternative for dried blood spot collection

Sofie VelgheChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

Molecular and evolutionary insights into folate metabolism in higher plants

Vera GorelovaDominique Van Der StraetenChristophe Stove

Molecular dissection of the human A3 adenosine receptor coupling with β-arrestin2

Jolien StormeAnnelies CannaertKathleen Van CraenenbroeckChristophe Stove

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

Probing structure-activity relationship in beta-arrestin2 recruitment of diversely substituted adenosine derivatives

Jolien StormeDilip K ToshZhan-Guo GaoKenneth A JacobsonChristophe Stove

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

Synthesis toward bivalent ligands for the dopamine D2 and metabotropic glutamate 5 receptors

Mingcheng QianElise WoutersJames AR DaltonMartijn RisseeuwRené CransChristophe StoveJesús GiraldoKathleen Van CraenenbroeckSerge Van Calenbergh

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Volumetric absorptive microsampling as an alternative tool for therapeutic drug monitoring of first-generation anti-epileptic drugs

Sofie VelgheChristophe Stove

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Wet absorptive microsampling at home for HbA(1c) monitoring in diabetic children

Nick VerougstraeteVeronique StoveChristophe Stove

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

β-Arrestin coupling to purinergic receptors : glo with the flow?

Jolien StormeChristophe Stove

2017

Activity-based detection of consumption of synthetic cannabinoids in authentic urine samples using a stable cannabinoid reporter system

Annelies CannaertFlorian FranzVolker AuwärterChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

Analytical confirmation of synthetic cannabinoids in a cohort of 179 presentations with acute recreational drug toxicity to an Emergency Department in London, UK in the first half of 2015

Rachelle AbouchedidSimon HudsonNatalie ThurtleTakahiro YamamotoJames H HoGeorge BaileyMichelle WoodNele SadonesChristophe StoveAlison Dines et al.

A1 Journal Article in CLINICAL TOXICOLOGY

Biomarkers in patients admitted to the emergency department after exposure to acrylonitrile in a major railway incident involving bulk chemical material

Sebastiaan ColenbieWalter BuylaertChristophe StoveEllen DeschepperKoenraad VandewoudeTom De SmedtMichael BaderThomas GöenAn Van NieuwenhuysePeter De Paepe

A1 Journal Article in INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Dihydrofolate reductase/thymidylate synthase fine-tunes the folate status and controls redox homeostasis in plants

Vera GorelovaJolien De LepeleireJeroen Van DaeleDick PluimColine MeiAnn CuypersOlivier LerouxFabrice RebeilleJan H SchellensDieter Blancquaert et al.

A1 Journal Article in PLANT CELL

Dried blood spot analysis of gabapentin as a valid alternative for serum : a bridging study

Nele SadonesElien Van BeverLucas Van BortelWilly LambertChristophe Stove

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Folates in plants : research advances and progress in crop biofortification

Vera GorelovaLars AmbachFabrice RébeilléChristophe StoveDominique Van Der Straeten

A1 Journal Article in FRONTIERS IN CHEMISTRY

Novel direct dried blood spot-based approaches for forensic toxicology and clinical applications

Nele SadonesChristophe StoveWilly Lambert

Should GM rice with nutrition benefits be deployed? : findings from biotech and socio-economic research

Hans De SteurDieter BlancquaertChristophe StoveWilly LambertDominique Van Der StraetenXavier Gellynck

Bookchapter in Genetically modified organisms in developing countries : risk analysis and governance

The (non)sense of routinely analysing beta-hydroxybutyric acid in forensic toxicology casework

Nele SadonesWilly LambertChristophe Stove

A1 Journal Article in FORENSIC SCIENCE INTERNATIONAL

Volumetric absorptive microsampling at home as an alternative tool for the monitoring of HbA1c in diabetes patients

Nick VerougstraeteBruno LapauwSara Van AkenJoris DelangheChristophe StoveVeronique Stove

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

2016

A novel, nondestructive, dried blood spot-based hematocrit prediction method using noncontact diffuse reflectance spectroscopy

Sara CapiauLeah S WilkMaurice CG AaldersChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

Alternative sampling strategies for cytochrome P450 phenotyping

Pieter De KeselWilly LambertChristophe Stove

A1 Journal Article in CLINICAL PHARMACOKINETICS

Alternative sampling strategies for the assessment of alcohol intake of living persons

Natalie KummerWilly LambertNele SamynChristophe Stove

A1 Journal Article in CLINICAL BIOCHEMISTRY

Alternative sampling strategies for therapeutic drug monitoring

Sara CapiauJan-Willem AlffenaarChristophe Stove

Bookchapter in Clinical challenges in therapeutic drug monitoring : special populations, physiological conditions and pharmacogenomics

Alternative sampling strategies to monitor alcohol consumption in case of driver's licence regranting

Natalie KummerChristophe StoveWilly LambertNele Samyn

Biological availability and efficacy of folates from bioengineered rice

Filip KiekensChristophe StoveWilly LambertDominique Van Der Straeten

Consumer acceptance and willingness-to-pay for genetically modified foods with enhanced vitamin levels

Hans De SteurDieter BlancquaertSimon StrobbeShuyi FengJeroen BuysseChristophe StoveWilly LambertDominique Van Der StraetenXavier Gellynck

Bookchapter in Genetically modified organisms in food : production, safety, regulation and public health

Degradation and interconversion of plant pteridines during sample preparation and ultra-high performance liquid chromatography-tandem mass spectrometry

Jeroen Van DaeleDieter BlancquaertFilip KiekensDominique Van Der StraetenWilly LambertChristophe Stove

A1 Journal Article in FOOD CHEMISTRY

Detection and activity profiling of synthetic cannabinoids and their metabolites with a newly developed bioassay

Annelies CannaertJolien StormeFlorian FranzVolker AuwärterChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

Disulfiram inhibition of cyanide formation after acetonitrile poisoning

Peter De PaepePieter ColinPieter DepuydtAn-Sofie DecaveleJulie De SmetKoen BousseryChristophe StoveDominique BenoitAlain VerstraeteJan Van Bocxlaer et al.

A1 Journal Article in CLINICAL TOXICOLOGY

Microwave-assisted on-spot derivatization for gas chromatography-mass spectrometry based determination of polar low molecular weight compounds in dried blood spots

Nele SadonesElien Van BeverJohn RH ArcherDavid M WoodPaul I DarganLucas Van BortelWilly LambertChristophe Stove

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Opening the toolbox of alternative sampling strategies in clinical routine : a key-role for (LC-)MS/MS

Sofie VelgheSara CapiauChristophe Stove

A1 Journal Article in TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Quantification of EtG in hair, EtG and EtS in urine and PEth species in capillary dried blood spots to assess the alcohol consumption in driver's licence regranting cases

Natalie KummerSarah MR WilleAnneleen PollWilly LambertNele SamynChristophe Stove

A1 Journal Article in DRUG AND ALCOHOL DEPENDENCE

Quantification of phosphatidylethanol 16:0/18:1, 18:1/18:1, and 16:0/16:0 in venous blood and venous and capillary dried blood spots from patients in alcohol withdrawal and control volunteers

Natalie KummerAnn-Sofie IngelsSarah MR WilleCatherine HanakPaul VerbanckWilly LambertNele SamynChristophe Stove

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Short-term health effects in the general population following a major train accident with acrylonitrile in Belgium

K SimonsT De SmedtChristophe StovePeter De PaepeM BaderB NemeryC VleminckxK De CremerI Van OvermeireS Fierens et al.

A1 Journal Article in ENVIRONMENTAL RESEARCH

2015

A caffeinated blend of alternative sampling strategies : from CYP1A2 phenotyping to issues in microsampling

Pieter De KeselChristophe StoveWilly Lambert

A validated ultra-high-performance liquid chromatography-tandem mass spectrometry method for the selective analysis of free and total folate in plasma and red blood cells

Filip KiekensJeroen Van DaeleDieter BlancquaertDominique Van Der StraetenWilly LambertChristophe Stove

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

An optimized and validated SPE-LC-MS/MS method for the determination of caffeine and paraxanthine in hair

Pieter De KeselWilly LambertChristophe Stove

A1 Journal Article in TALANTA

Application of oral fluid and dried blood spots as a matrix for roadside drug testing

Sarah WilleAnn-Sofie IngelsNele Samyn

Bookchapter in New sampling strategies in toxicology and therapeutic drug monitoring

Are capillary DBS applicable for therapeutic drug monitoring of common antipsychotics? : a proof of concept

Lisbeth PatteetKristof E MaudensChristophe StoveWilly LambertManuel MorrensBernard SabbeHugo Neels

A1 Journal Article in BIOANALYSIS

Determination of five folate monoglutamates in rodent diets

Filip KiekensJeroen Van DaeleDieter BlancquaertDominique Van Der StraetenWilly LambertChristophe Stove

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Do capillary dried blood spot concentrations of gamma-hydroxybutyric acid mirror those in venous blood? : a comparative study

Nele SadonesJohn RH ArcherAnn-Sofie IngelsPaul I DarganDavid M WoodMichelle WoodHugo NeelsWilly LambertChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

Does volumetric absorptive microsampling eliminate the hematocrit bias for caffeine and paraxanthine in dried blood samples? : a comparative study

Pieter De KeselWilly LambertChristophe Stove

A1 Journal Article in ANALYTICA CHIMICA ACTA

Folates from metabolically engineered rice: a long-term study in rats

Filip KiekensDieter BlancquaertLindsey DevisscherJeroen Van DaeleVeronique StoveJoris DelangheDominique Van Der StraetenWilly LambertChristophe Stove

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

Improving folate (vitamin B-9) stability in biofortified rice through metabolic engineering

Dieter BlancquaertJeroen Van DaeleSimon StrobbeFilip KiekensSerguei StorojenkoHans De SteurXavier GellynckWilly LambertChristophe StoveDominique Van Der Straeten

A1 Journal Article in NATURE BIOTECHNOLOGY

New sampling strategies in toxicology and therapeutic drug monitoring

Paraxanthine/caffeine concentration ratios in hair: an alternative for plasma-based phenotyping of cytochrome P450 1A2?

Pieter De KeselWilly LambertChristophe Stove

A1 Journal Article in CLINICAL PHARMACOKINETICS

Role of therapeutic drug monitoring in pulmonary infections : use and potential for expanded use of dried blood spot samples

Susan HofmanMathieu S BolhuisRemco A KosterOnno W AkkermanSander van AssenChristophe StoveJan-Willem C Alffenaar

A1 Journal Article in BIOANALYSIS

The role of (bio)markers in hair analysis

Pieter De KeselWilly LambertChristophe Stove

Bookchapter in New sampling strategies in toxicology and therapeutic drug monitoring

The use of dried blood spots for quantification of 15 antipsychotics and 7 metabolites with ultra-high performance liquid chromatography-tandem mass spectrometry

Lisbeth PatteetKristof E MaudensChristophe StoveWilly LambertManuel MorrensBernard SabbeHugo Neels

A1 Journal Article in DRUG TESTING AND ANALYSIS

2014

Acrylonitrile exposure assessment in the emergency responders of a major train accident in Belgium: a human biomonitoring study

A Van NieuwenhuyseS FierensT De SmedtK De CremerC VleminckxB MertensI Van OvermeireM BaderPeter De PaepeT Goen et al.

A1 Journal Article in TOXICOLOGY LETTERS

Acrylonitrile exposure in the general population following a major train accident in Belgium: a human biomonitoring study

T De SmedtK De CremerC VleminckxS FierensB MertensI Van OvermeireM BaderPeter De PaepeT GoenB Nemery et al.

A1 Journal Article in TOXICOLOGY LETTERS

Assessing the validity of capillary dried blood spots used for gamma-hydroxybutyrate analysis from patients suspected of toxicity attending the emergency department

John RH ArcherAnn-Sofie IngelsPaul I DarganDavid M WoodChristophe Stove

Current strategies for coping with the hematocrit problem in dried blood spot analysis

Pieter De KeselSara CapiauWilly LambertChristophe Stove

Editorial material

CYP1A2 phenotyping in dried blood spots and microvolumes of whole blood and plasma

Pieter De KeselWilly LambertChristophe Stove

A1 Journal Article in BIOANALYSIS

Derivatization techniques in dried blood spot analysis

Ann-Sofie IngelsNele SadonesPieter De KeselWilly LambertChristophe Stove

Bookchapter in Dried blood spots : applications and techniques

Development of a new haptoglobin genotyping method by direct PCR on dried blood spots

Nele SadonesLien OnderbekeAnnelies CannaertPieter De KeselJoris DelangheWilly LambertChristophe Stove

Disulfiram inhibition of cyanide formation after acetonitrile poisoning

Peter De PaepePieter ColinPieter DepuydtAn-Sofie DecaveleJulie De SmetKoen BousseryChristophe StoveDominique BenoitAlain VerstraeteJan Van Bocxlaer et al.

Drug analysis and clinical effects in patients attending the emergency department with suspected gamma-hydroxybutyrate toxicity

John RH ArcherAnn-Sofie IngelsDavid M WoodMichelle WoodPaul I DarganChristophe Stove

Folate profiling in potato (Solanum tuberosum) tubers by ultrahigh-performance liquid chromatography-tandem mass spectrometry

Jeroen Van DaeleDieter BlancquaertFilip KiekensDominique Van Der StraetenWilly LambertChristophe Stove

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Overcoming all issues associated with dried blood sampling?: the case of CYP1A2 phenotyping

Pieter De KeselWilly LambertChristophe Stove

Potassium-based algorithm allows correction for the hematocrit bias in quantitative analysis of caffeine and its major metabolite in dried blood spots

Pieter De KeselSara CapiauVeronique StoveWilly LambertChristophe Stove

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Screening and confirmation methods for GHB determination in biological fluids

Ann-Sofie IngelsSarah MR WilleNele SamynWilly LambertChristophe Stove

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Spot them in the spot : analysis of abused substances using dried blood spots

Nele SadonesSara CapiauPieter De KeselWilly LambertChristophe Stove

A1 Journal Article in BIOANALYSIS

Why dried blood spots are an ideal tool for CYP1A2 phenotyping

Pieter De KeselWilly LambertChristophe Stove

A1 Journal Article in CLINICAL PHARMACOKINETICS

2013

Biofortified rice to fight folate deficiency

Dieter BlancquaertOscar NavarreteSerguei StorojenkoHans De SteurJeroen Van DaeleWei DongCailin LeiChunyi ZhangChristophe StoveXavier Gellynck et al.

Bookchapter in Handbook of food fortification and health : from concepts to public health applications, volume 1

Determination of gamma-hydroxybutyric acid in biofluids using a one-step procedure with 'in-vial' derivatization and headspace-trap gas chromatography-mass spectrometry

Ann-Sofie IngelsHugo NeelsWilly LambertChristophe Stove

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Determination of gamma-hydroxybutyric acid in microvolumes of biological fluids following direct derivatization and gas chromatography mass spectrometry

Ann-Sofie IngelsChristophe StoveWilly Lambert

Dried blood spots as an alternative sampling strategy for CYP1A2 phenotyping

Pieter De KeselWilly LambertChristophe Stove

Enhancing pterin and para-aminobenzoate content is not sufficient to successfully biofortify potato tubers and Arabidopsis thaliana plants with folate

Dieter BlancquaertSerguei StorojenkoJeroen Van DaeleChristophe StoveRichard GF VisserWilly LambertDominique Van Der Straeten

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

Fatality following a suicidal overdose with varenicline

Christophe StoveEls De LetterMichel PietteWilly Lambert

A1 Journal Article in INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Feasibility of following up gamma-hydroxybutyric acid concentrations in sodium oxybate (Xyrem)-treated narcoleptic patients using dried blood spot sampling at home : an exploratory study

Ann-Sofie IngelsKatrien HertegonneWilly LambertChristophe Stove

Feasibility of following up gamma-hydroxybutyric acid concentrations in sodium oxybate (Xyrem®)-treated narcoleptic patients using dried blood spot sampling at home : an exploratory study

Ann-Sofie IngelsKatrien HertegonneWilly LambertChristophe Stove

A1 Journal Article in CNS DRUGS

Hemato-critical issues in quantitative analysis of dried blood spots: challenges and solutions

Pieter De KeselNele SadonesSara CapiauWilly LambertChristophe Stove

A1 Journal Article in BIOANALYSIS

Isolation and characterisation of an antifolate insensitive (afi1) mutant of Arabidopsis thaliana

Oscar NavarreteJeroen Van DaeleChristophe StoveWilly LambertSerguei StorojenkoDominique Van Der Straeten

A1 Journal Article in PLANT BIOLOGY

One for all, all in one : determination of gamma-hydroxybutyric acid in biofluids using 'in-vial' derivatization and headspace-trap gas chromatography-mass spectrometry

Ann-Sofie IngelsH NeelsWilly LambertChristophe Stove

One for all, all in one : determination of gamma-hydroxybutyric acid in biofluids using 'in-vial' derivatization and headspace-trap gas chromatography-mass spectrometry

Ann-Sofie IngelsH NeelsWilly LambertChristophe Stove

Prediction of the hematocrit of dried blood spots via potassium measurement on a routine clinical chemistry analyzer

Sara CapiauVeronique StoveWilly LambertChristophe Stove

A1 Journal Article in ANALYTICAL CHEMISTRY

Prediction of the hematocrit of dried blood spots via potassium measurement on a routine clinical chemistry analyzer

Sara CapiauVeronique StoveWilly LambertChristophe Stove

Quantitation of gamma-hydroxybutyric acid in dried blood spots in newborn screening

Christophe StoveAnn-Sofie IngelsWilly Lambert

A1 Journal Article in MOLECULAR GENETICS AND METABOLISM

Rice folate enhancement through metabolic engineering has an impact on rice seed metabolism, but does not affect the expression of the endogenous folate biosythesis genes

Dieter BlancquaertJeroen Van DaeleSerguei StorojenkoChristophe StoveWilly LambertDominique Van Der Straeten

A1 Journal Article in PLANT MOLECULAR BIOLOGY

2012

A folate independent role for cytosolic HPPK/DHPS upon stress in Arabidopsis thaliana

Oscar NavarreteJeroen Van DaeleChristophe StoveWilly LambertDominique Van Der StraetenSerguei Storojenko

A1 Journal Article in PHYTOCHEMISTRY

Dried blood spots in toxicology : from the cradle to the grave?

Christophe StoveAnn-Sofie IngelsPieter De KeselWilly Lambert

A1 Journal Article in CRITICAL REVIEWS IN TOXICOLOGY

Inhibition of p-aminobenzoate and folate syntheses in plants and apicomplexan parasites by natural product rubreserine

Djeneb CamaraCordelia BisanzCaroline BaretteJeroen Van DaeleEsmare HumanBernice BarnardDominique Van Der StraetenChristophe StoveWilly LambertRoland Douce et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of α-catulin with dystrobrevin contributes to integrity of dystrophin complex in muscle

Hyun J OhLinu S AbrahamJolanda van HengelChristophe StoveTomasz J ProszynskiKris GevaertJoseph X DiMarioJoshua R SanesFrans Van RoyHongkyun Kim

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2011

A suicidal fatality following an overdose with varenicline

Christophe StoveEls De LetterMichel PietteWilly Lambert

Determination of GHB in dried blood spots with "on spot" derivatization and GC-MS: method development, validation and application

Ann-Sofie IngelsPeter De PaepeK AnseeuwD Van SassenbroeckH NeelsWilly LambertChristophe Stove

Dried blood spot punches for confirmation of suspected γ-hydroxybutyric acid intoxications : validation of an optimized GC-MS procedure

Ann-Sofie IngelsPeter De PaepeKurt AnseeuwDiederik Van SassenbroeckHugo NeelsWilly LambertChristophe Stove

A1 Journal Article in BIOANALYSIS

P-cadherin in adhesion and invasion: opposite roles in colon and bladder carcinoma

Veerle Van MarckChristophe StoveKoen JacobsGert Van den EyndenMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Quantitative liquid chromatographic analysis of anthracyclines in biological fluids

Kristof MaudensChristophe StoveWilly Lambert

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells

Lara DeryckeChristophe StoveAnne-Sophie Vercoutter-EdouartOlivier De WeverLaurent DolléNathalie ColpaertHerman DepypereJean-Claude MichalskiMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

2010

A field study on 8 pharmaceuticals and 1 pesticide in Belgium: removal rates in waste water treatment plants and occurrence in surface water

Jet Van De SteeneChristophe StoveWilly Lambert

A1 Journal Article in SCIENCE OF THE TOTAL ENVIRONMENT

Determination of gamma-hydroxybutyric acid in dried blood spots using a simple GC-MS method with direct 'on spot' derivatization

Ann-Sofie IngelsWilly LambertChristophe Stove

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Mice in ecstasy : advanced animal models in the study of MDMA

Christophe StoveEls De LetterMichel PietteWilly Lambert

A1 Journal Article in CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Post-mortem (re)distribution of 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy') : human and animal data

Els De LetterChristophe StoveWilly LambertMichel Piette

A1 Journal Article in CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The transcriptional repressor Kaiso localizes at the mitotic spindle and is a constituent of the pericentriolar material

Adelheid SoubryKatrien StaesEef ParthoensSamuel NoppenChristophe StovePieter BogaertJolanda van HengelFrans Van Roy

A1 Journal Article in PLOS ONE

Ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) for the sensitive determination of folates in rice

Veerle De BrouwerSerguei StorojenkoChristophe StoveJeroen Van DaeleDominique Van Der StraetenWilly Lambert

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

2009

Determination of folate monoglutamates in biofortified rice with UPLC-MS/MS

Veerle De BrouwerSerguei StorojenkoChristophe StoveDominique Van Der StraetenWilly Lambert

A1 Journal Article in PTERIDINES

Development and validation of a liquid chromatographic method for the simultaneous determination of four anthracyclines and their respective 13-S-dihydro metabolites in plasma and saliva

Kristof MaudensChristophe StoveVeronique CocquytHannelore DenysWilly Lambert

A1 Journal Article in Journal of Chromatography B

2008

Optimisation and validation of a liquid chromatography-tandem mass spectrometry method for folates in rice

Veerle De BrouwerSerguei StorojenkoJet Van De SteeneSarah WilleChristophe StoveDominique Van Der StraetenWilly Lambert

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Optimization of a liquid chromatographic separation for the simultaneous determination of four anthracyclines and their respective 13-S-dihydro metabolites

Kristof MaudensChristophe StoveWilly Lambert

A1 Journal Article in JOURNAL OF SEPARATION SCIENCE

2006

E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion

Kristin StrumaneArnaud BonnometChristophe StoveRoosmarijn VandenbrouckeBeatrice Nawrocki-RabyErik BruyneelMarcus MareelPhilippe BirembautGeert BerxFrans Van Roy

A1 Journal Article in CANCER RESEARCH

2005

Bowes melanoma cells secrete heregulin, which can promote aggregation and counteract invasion of human mammary cancer cells

Christophe StoveTom BoterbergVeerle Van MarckMarcus Mareelmarc bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8 alpha beta

Veronique StoveInge Van de WalleEvelien NaessensElisabeth CoeneChristophe StoveJean PlumBruno Verhasselt

A1 Journal Article in JOURNAL OF VIROLOGY

P-cadherin promotes cell-cell adhesion and counteracts invasion in human melanoma

Veerle Van MarckChristophe StoveKarolien Van Den BosscheVeronique StoveJoana ParedesYves Vander HaeghenMarc Bracke

A1 Journal Article in CANCER RESEARCH

The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program

Bram De CraeneBarbara GilbertChristophe StoveErik BruyneelFrans Van RoyGeert Berx

A1 Journal Article in CANCER RESEARCH

2004

Melanoma cells secrete follistatin, an antagonist of activin-mediated growth inhibition

Christophe StoveFrank VanrobaeysBart DevreeseJozef Van BeeumenMarcus Mareelmarc bracke

A1 Journal Article in ONCOGENE

New regulatory molecules in growth and invasion of melanoma and breast cancer: cadherins, heregulin and follistatin

Christophe StoveM Bracke

P-cadherin is up-regulated by the antiestrogen ICI 182,780 and promotes invasion of human breast cancer cells

Joana ParedesChristophe StoveVeronique StoveFernanda MilaneziVeerle Van MarckLara DeryckeMarcus MareelMarc BrackeFernando Schmitt

A1 Journal Article in CANCER RESEARCH

Roles for neuregulins in human cancer

Christophe Stovemarc bracke

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

Soluble N-cadherin fragments: a new indicator of invasion. Vol. 59(2)

Lara DeryckeChristophe StoveMarieke GoossensVeerle Van MarckMarc Bracke

2003

New monoclonal antibodies for human N-cadherin.

Lara DeryckeChristophe StoveMarcus MareelMarc Bracke

Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development

Veronique StoveEvelien NaessensChristophe StoveT SWIGUTJean PlumBruno Verhasselt

A1 Journal Article in BLOOD

SP-06 A new clue for the resistance of malignant melanoma? Follistatin secretion overcomes activin-mediated growth inhibition

Christophe StoveFrank VanrobaeysBart DevreeseJozef Van BeeumenMarcus MareelMarc Bracke

Synthesis, characterization and in vitro anti-invasive activity screening of polyphenolic and heterocyclic compounds

VS PARMARNK SHARMAM HUSAINAC WATTERSONJ KUMARLA SAMUELSONAL CHOLLIAK PRASADS MALHOTRAN KUMAR et al.

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

The heregulin/human epidermal growth factor receptor as a new growth factor system in melanoma with multiple ways of deregulation

Christophe StoveVeronique StoveLara DeryckeVeerle Van MarckMarcus Mareelmarc bracke

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

2002

8-prenylnaringenin, the phytooestrogen in hops and beer, may influence the incidence of breast cancer.

Herman DepypereH RONGTom BoterbergR SERREYNChristophe StoveSABINE VAN SLAMBROUCKDenis De KeukeleireMarcus Mareelmarc bracke

Effects of tangeretin on human cell-cell interactions

Marc BrackeTom BoterbergHerman DepypereChristophe StoveGeorges LeclercqG VandecasteeleMarcus Mareel

Plasmin produces an E-cadherin fragment that stimulates cancer cell invasion.

F RYNIERSChristophe StoveM GOETHALSL BRACKENIERV NOEmarc brackeJoël VandekerckhoveMarcus MareelErik Bruyneel

A1 Journal Article in BIOLOGICAL CHEMISTRY

The citrus methoxyflavone tangeretin affects human cell-cell interactions

marc brackeTom BoterbergHerman DepypereChristophe StoveGeorges LeclercqMarcus Mareel

A1 Journal Article in FLAVONOIDS IN CELL FUNCTION

2001

8-Prenylnaringenin, the phytoestrogen in hops and beer, upregulates the function of the E-cadherin/catenin complex in human mammary carcinoma cells

Haojing RongTom BoterbergJulie MaubachChristophe StoveHerman DepypereSéverine Van SlambrouckRudolphe SerreynDenis De KeukeleireMarcus MareelMarc Bracke

A1 Journal Article in EUROPEAN JOURNAL OF CELL BIOLOGY

An anti-invasive factor in the conditioned medium of a melanoma cell line: signaling via the ErbB receptors?

Christophe StoveTom BoterbergLara DeryckeD VANDEKERKHOVEMarcus MareelMarc Bracke