Research Explorer

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Researcher

Christophe Ampe

153 Results

2023

Acid‐resistant BODIPY amino acids for peptide‐based fluorescence imaging of GPR54 receptors in pancreatic islets

Lorena Mendive-TapiaLaia Miret CasalsNicole BarthJinling WangAnne de BrayMassimiliano BeltramoVincent RobertChristophe AmpeDavid HodsonAnnemieke Madder et al.

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multisite assessment of reproducibility in high‐content cell migration imaging data

Jianjiang HuXavier Serra‐PicamalGert‐Jan BakkerMarleen Van TroysSabina Winograd‐KatzNil EgeXiaowei GongYuliia DidanInna GroshevaOmer Polansky et al.

A1 Journal Article in MOLECULAR SYSTEMS BIOLOGY

2022

Innovative mouse models for the tumor suppressor activity of protocadherin-10 isoforms

Irene KleinbergerEllen SandersKatrien StaesMarleen Van TroysShinji HiranoTino HochepiedKelly LemeireLiesbet MartensChristophe AmpeFrans Van Roy

A1 Journal Article in BMC CANCER

2021

Cancer type-specific alterations in actin genes : worth a closer look?

Christophe AmpeLaura WitjesMarleen Van Troys

Bookchapter in Actin cytoskeleton in cancer progression and metastasis : part C

Furan warheads for covalent trapping of weak protein-protein interactions : cross-linking of thymosin β4 to actin

Laia Miret CasalsWillem VanneckeKurt HoogewijsGianluca Arauz-GarofaloMarina GayMireia Diaz-LoboMarta VilasecaChristophe AmpeMarleen Van TroysAnnemieke Madder

A1 Journal Article in CHEMICAL COMMUNICATIONS

2020

Community standards for open cell migration data

Alejandra N. Gonzalez-BeltranPaola MasuzzoChristophe AmpeGert-Jan BakkerSébastien BessonRobert H EiblPeter FriedlMatthias GunzerMark KittisopikulSylvia E. Le Dévédec et al.

A1 Journal Article in GIGASCIENCE

Cytoplasmic actin mutations

Christophe AmpeLaura Witjes

Prevalence of cytoplasmic actin mutations in diffuse large B-cell lymphoma and multiple myeloma : a functional assessment based on actin three-dimensional structures

Laura WitjesMarleen Van TroysBruno VerhasseltChristophe Ampe

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Time for rethinking the different β‐actin transgenic mouse models?

Bieke VanslembrouckChristophe AmpeJolanda van Hengel

A1 Journal Article in CYTOSKELETON

Vertebrate actin evolution and the assessment of mutations in cytoplasmic actins in DLBCL and multiple myeloma

Laura WitjesChristophe AmpeBruno Verhasselt

2019

A new evolutionary model for the vertebrate actin family including two novel groups

Laura WitjesMarleen Van TroysJoël VandekerckhoveKlaas VandepoeleChristophe Ampe

A1 Journal Article in MOLECULAR PHYLOGENETICS AND EVOLUTION

Intercalated discs : specialized cytoskeletal anchors in cardiac muscle

Jolanda van HengelMaarten De SmetAnna KremerSaskia LippensMarjolijn RenardChristophe AmpeBieke Vanslembrouck

2018

An emerging link between LIM domain proteins and nuclear receptors

Stefano SalaChristophe Ampe

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Analysis of invasion dynamics of matrix-embedded cells in a multisample format

Marleen Van TroysPaola MasuzzoLynn HuyckKarima BakkaliDavy WaterschootLennart MartensChristophe Ampe

Bookchapter in Cell migration : methods and protocols

Combination of EGFR inhibitor lapatinib and MET inhibitor foretinib inhibits migration of triple negative breast cancer cell lines

Aleksandra SimiczyjewEwelina DratkiewiczMarleen Van TroysChristophe AmpeIlona StyczeńDorota Nowak

A1 Journal Article in CANCERS

Concerted biophysical and biological evaluation of Pseudomonas lipopeptides as a premise to unlock their application potential

José MartinsYentl VerleysenBenjámin KovácsVic De RooChristophe AmpeAnnemieke MadderMarleen Van TroysNiels Geudens

Exploration of CLP antitumor potential

Yentl VerleysenMatthias De VleeschouwerNiels GeudensMarleen Van TroysChristophe AmpeAnnemieke MadderJosé Martins

Influence of CLP structure on antitumor potential

Yentl VerleysenMatthias De VleeschouwerNiels GeudensTim Van KersavondArend MandelingsMarleen Van TroysChristophe AmpeAnnemieke MadderJosé Martins

Surveillance of myelodysplastic syndrome via migration analyses of blood neutrophils : a potential prognostic tool

Marc SchusterMischa MoellerLea BornemannClara BessenCharlyn SobczakSaskia SchmitzLaura WitjesKatja KruithoffChristina KohnOlga Just et al.

A1 Journal Article in JOURNAL OF IMMUNOLOGY

2017

An end-to-end software solution for the analysis of high-throughput single-cell migration data

Paola MasuzzoLynn HuyckAleksandra SimiczyjewChristophe AmpeLennart MartensMarleen Van Troys

A1 Journal Article in SCIENTIFIC REPORTS

Cross-linking furan-modified kisspeptin-10 to the KISS receptor

Willem VanneckeChristophe AmpeMarleen Van TroysMassimiliano BeltramoAnnemieke Madder

A1 Journal Article in ACS CHEMICAL BIOLOGY

Crosslinking furan-modified peptides to their target : towards a new receptor identification strategy

Willem VanneckeAnnemieke MadderChristophe Ampe

Expanding the interactome of TES by exploiting TES modules with different subcellular localizations

Stefano SalaMarleen Van TroysSandrine MedvesMarie CatillonEvy TimmermanAn StaesElisabeth Schaffner-ReckingerKris GevaertChristophe Ampe

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Structure-function study of the focal adhesion protein and tumour suppressor testin : determination of module-specific interactomes and expansion of its conformational repertoire

Stefano SalaChristophe AmpeMarleen Van Troys

The PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions

Stefano SalaMarie CatillonErmin HadzicElisabeth Schaffner-ReckingerMarleen Van TroysChristophe Ampe

A1 Journal Article in PLOS ONE

2016

An actomyosin-like cytoskeleton in the cyanobiont (Nosctoc sp.) of Peltigera canina

Eva-María DiazChristophe AmpeMarleen Van TroysMiguel Vicente-ManzanaresMaría-Estrella LegazCarlos Vicente

A1 Journal Article in PHYTOCHEMISTRY LETTERS

Furan-based crosslinking in situ : seizing ligand-receptor complexes in the act

Willem VanneckeChristophe AmpeMarleen Van TroysAnnemieke Madder

Mammalian actins : isoform-specific functions and diseases

Christophe AmpeMarleen Van Troys

Bookchapter in The actin cytoskeleton

Taking aim at moving targets in computational cell migration

Paola MasuzzoMarleen Van TroysChristophe AmpeLennart Martens

A1 Journal Article in TRENDS IN CELL BIOLOGY

The unfolded protein response underlies microenvironmental stress-induced phenotype switching leading to stemness and chemoresistance in human hepatocellular carcinoma

Yves-Paul VandewynckelO GovaereAster VandierendonckDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsSarah RaevensXavier VerhelstChristophe Van Steenkiste et al.

Towards an open data exchange ecosystem : forging a new path for cell migration data analysis and mining

Paola MasuzzoChristophe AmpeLennart MartensMarleen Van Troys

2015

Active invadopodia of mesenchymally migrating cancer cells contain both β and γ cytoplasmic actin isoforms

Aleksandra SimiczyjewAntonina Joanna MazurChristophe AmpeMaria Malicka-BłaszkiewiczMarleen Van TroysDorota Nowak

A1 Journal Article in EXPERIMENTAL CELL RESEARCH

An open data ecosystem for cell migration research

Paola MasuzzoLennart Martensthe 2014 Cell Migration workshop participantsChristophe AmpeOlivier De WeverMarleen Van Troys

Editorial material

Delineating the Tes interaction site in zyxin and studying cellular effects of its disruption

Ermin HadzicMarle CatillonAllaksandr HalavatyiSandrine MedvesMarleen Van TroysMichèle MoesMichelle A BairdMichael W DavidsonElisabeth Schaffner-ReckingerChristophe Ampe et al.

A1 Journal Article in PLOS ONE

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsXavier VerhelstAnja Van den BusscheSarah RaevensChristophe Van SteenkisteMarleen Van Troys et al.

A1 Journal Article in ONCOTARGET

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsXavier VerhelstA Van den BusscheSarah RaevensChristophe Van SteenkisteMarleen Van Troys et al.

2014

Beta-actin is required for proper mouse neural crest ontogeny

Davina TondeleirRivka NoelandersKarima BakkaliChristophe Ampe

A1 Journal Article in PLOS ONE

β-Agonists selectively modulate proinflammatory gene expression in skeletal muscle cells via non-canonical nuclear crosstalk mechanisms

Krzysztof KolmusMarleen Van TroysKarlien Van WesemaelChristophe AmpeGuy HaegemanJan TavernierSarah Gerlo

A1 Journal Article in PLOS ONE

2013

Alphaherpesviral US3 kinase induces cofilin dephosphorylation to reorganize the actin cytoskeleton

Thary JacobCeline Van den BroekeMarleen Van TroysDavy WaterschootChristophe AmpeHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

Beta-actin as a regulator of crucial developmental processes : focus on a nuclear role for beta-actin

Davina TondeleirChristophe Ampe

Beta-actin is involved in modulating erythropoiesis during development by fine-tuning Gata2 expression levels

Davina TondeleirBenjamin DrogatKarolina SlowickaKarima BakkaliSona BartunkovaSteven GoossensJody HaighChristophe Ampe

A1 Journal Article in PLOS ONE

Biophysical approaches for investigation of the cytoskeleton: a special issue stemming from research presented at the 2012 ECF meeting: a FEBS/EMBO workshop lecture course in Pécs, Hungary

Christophe AmpeLaura M MacheskyMiklós Nyitrai

Editorial material

CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASP

Andrea DisanzaSara BisiMoritz WinterhoffFrancesca MilanesiDmitry S UshakovDavid KastPaola MarighettiGuillaume Romet-LemonneHans-Michael MüllerWalter Nickel et al.

A1 Journal Article in EMBO JOURNAL

CellMissy: a tool for management, storage and analysis of cell migration data produced in wound healing-like assays

Paola MasuzzoNiels HulstaertLynn HuyckChristophe AmpeMarleen Van TroysLennart Martens

A1 Journal Article in BIOINFORMATICS

p210bcr-abl induces amoeboid motility by recruiting ADF/destrin through RhoA/ROCK1

Tristan RochelleThomas DaubonMarleen Van TroysThomas HarnoisDavy WaterschootChristophe AmpeLydia RoyNicolas BourmeysterBruno Constantin

A1 Journal Article in FASEB JOURNAL

β-actin knock-out mouse embryonic fibroblasts show increased expression of LIM-, CH-, EFh-domain containing proteins with predicted common upstream regulators

Christophe AmpeJelle LibbrechtMarleen Van Troys

A1 Journal Article in CYTOSKELETON

2012

Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity

Davina TondeleirAnja LambrechtsMatthias MüllerVeronique JonckheereThierry DollDrieke VandammeKarima BakkaliDavy WaterschootMarianne LemaistreOlivier Debeir et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Phosphosite conservation in single domain orthologs versus paralogs: a way to combine differential regulation with redundant core functions

Lynn HuyckMarleen Van TroysChristophe Ampe

A1 Journal Article in FEBS LETTERS

The US3 kinase of pseudorabies virus leads to activation of the actin regulator cofilin to induce actin cytoskeleton changes

Thary JacobCeline Van den BroekeMarleen Van TroysDavy WaterschootChristophe AmpeHerman Favoreel

The XTT cell proliferation assay applied to cell layers embedded in three-dimensional matrix

Lynn HuyckChristophe AmpeMarleen Van Troys

A1 Journal Article in ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

2011

A QUICK screen for Lrrk2 interaction partners: leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics

Andrea MeixnerKarsten BoldtMarleen Van TroysManor AskenaziChrsitian J GloecknerMatthias BauerJarrod A MartoChristophe AmpeNorbert KinklMarius Ueffing

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Actin and actin filaments

Davina TondeleirChristophe AmpeJoël Vandekerckhove

Intermolecular interaction studies using small volumes

David BourryDavy SinnaeveKatelijne GheysenBernd FritzingerGianni VandenborreEls Van DammeJean-Michel WieruszeskiGuy LippensChristophe AmpeJosé Martins

A1 Journal Article in MAGNETIC RESONANCE IN CHEMISTRY

2010

Ena/VASP proteins: focus on interaction partners and Enah splice variants

Sylvie VeniereChristophe Ampe

Identification and expression analysis of splice variants of mouse enabled homologue during development and in adult tissues

Sylvie VeniereDavy WaterschootJoël VandekerckhoveAnja LambrechtsChristophe Ampe

A1 Journal Article in BMC MOLECULAR BIOLOGY

2009

Actin isoform expression patterns during mammalian development and in pathology: insights from mouse models

Davina TondeleirDrieke VandammeJoël VandekerckhoveChristophe AmpeAnja Lambrechts

A1 Journal Article in CELL MOTILITY AND THE CYTOSKELETON

Algemene biochemie: functionele bouwstenen van het leven

Christophe AmpeBart Devreese

Alpha-actin mutations in congenital myopathies: identification of cell death as a new cellular Nemaline Myopathy phenotype and induction of similar cytoskeletal defects by mutants associated with different myopathies

Drieke VandammeChristophe Ampe

An integrative simulation model linking major biochemical reactions of actin-polymerization to structural properties of actin filaments

Aliaksandr A. HalavatyiPetr V. NazarovSandrine MedvesMarleen Van TroysChristophe AmpeMikalai YatskouEvelyne Friederich

A1 Journal Article in BIOPHYSICAL CHEMISTRY

Exploring the stability of the villin HeadPiece fold and the interaction of villin HeadPiece and profilin with polyphosphoinositides

David BourryJosé MartinsChristophe Ampe

Impaired neural crest migration contributes to midgestation lethality of beta-actin knock-out mouse

Davina TondeleirMatthias MuellerVeronique JonckheereDavy WaterschootKarima BakkaliJoël VandekerckhoveChristophe AmpeAnja Lambrechts

Phenotypes induced by NM causing α-skeletal muscle actin mutants in fibroblasts, Sol 8 myoblasts and myotubes

Drieke VandammeEllen LambertDavy WaterschootDavina TondeleirLaura M MacheskyJoël VandekerckhoveBruno ConstantinHeidi RommelaereChristophe Ampe

A2 Journal Article in BMC RESEARCH NOTES

The Interaction of Proline-Rich Ligands with Profilin Probed with an Enzyme-Linked Immunosorbent Assay

Sylvie VeniereChristophe AmpeJoël VandekerckhoveAnja Lambrechts

A1 Journal Article in JOURNAL OF BIOMOLECULAR SCREENING

The Mouse Thymosin Beta15 Gene Family Displays Unique Complexity and Encodes A Functional Thymosin Repeat

Stien DhaeseKlaas VandepoeleDavy WaterschootBerlinda VanlooJoël VandekerckhoveChristophe AmpeMarleen Van Troys

A1 Journal Article in JOURNAL OF MOLECULAR BIOLOGY

Unbalancing the phosphatidylinositol-4,5-bisphosphate-cofilin interaction impairs cell steering

Shirley LeymanMazen SidaniLaila RitsmaDavy WaterschootRobert EddyDaisy DewitteOlivier DebeirChristine DecaesteckerJoël VandekerckhoveJacco van Rheenen et al.

A1 Journal Article in MOLECULAR BIOLOGY OF THE CELL

alpha-Skeletal Muscle Actin Mutants Causing Different Congenital Myopathies Induce Similar Cytoskeletal Defects in Cell Line Cultures

Drieke VandammeHeidi RommelaereEllen LambertDavy WaterschootJoël VandekerckhoveBruno ConstantinChristophe Ampe

A1 Journal Article in CELL MOTILITY AND THE CYTOSKELETON

alpha-Skeletal muscle actin nemaline myopathy mutants cause cell death in cultured muscle cells.

Drieke VandammeEllen LambertDavy WaterschootC. CognardJoël VandekerckhoveChristophe AmpeB. ConstantinHeidi Rommelaere

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

2008

Ins and outs of ADF/cofilin activity and regulation

Marleen Van TroysLynn HuyckShirley LeymanStien DhaeseJoël VandekerckhoveChristophe Ampe

A1 Journal Article in EUROPEAN JOURNAL OF CELL BIOLOGY

Predicting the effect of a point mutation on a protein fold: The villin and advillin headpieces and their Pro62Ala mutants

S PIANAA LAIOF MARINELLIMarleen Van TroysDavid BourryChristophe AmpeJosé Martins

A1 Journal Article in JOURNAL OF MOLECULAR BIOLOGY

S100B Expression in forensic brain trauma fatalities: a valuable tool?

Els De LetterMarc EspeelFrederik BerlengeeChristophe AmpeJoél SmetRudy Van CosterMichel Piette

2007

Atomistic Prediction of the structure of the Advillin headpiece and its Pro62Ala mutant

José MartinsA LAIOF MARINELLIMarleen Van TroysChristophe AmpeDavid BourryS PIANO

Functional and profiling studies prove that prostate cancer upregulated neuroblastoma thymosin beta is the true human homologue of rat thymosin beta 15

Stien DhaeseVeronique JonckheereMarc GoethalsD WALTREGNYJoël VandekerckhoveChristophe AmpeMarleen Van Troys

A1 Journal Article in FEBS LETTERS

On the origin and evolution of vertebrate and viral profilins

Debby PoletAnja LambrechtsKlaas VandepoeleJoël VandekerckhoveChristophe Ampe

A1 Journal Article in FEBS LETTERS

Structural and Functional Implicationof the PXWK-motif in HeadPiece Domains

David BourryW VERMEULENMarleen Van TroysJoël VandekerckhoveChristophe AmpeJosé Martins

Structural and Functional Implications of the PXWK-motif in HeadPiece Domains

David BourryW VERMEULENMarleen Van TroysJoël VandekerckhoveChristophe AmpeJosé Martins

Structure-function relationship of actin binding modules studied by NMR

David BourryMarleen Van TroysM DUMOULINA MATAGNEChristophe AmpeJosé Martins

The LIM domains of WLIM1 define a new class of actin bundling modules

C THOMASF MOREAUM DIETERLEC HOFFMANNS GATTIC HOFMANNMarleen Van TroysChristophe AmpeA STEINMETZ

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2006

Actin interacts with CCT via discrete binding sites: A binding transition-release model for CCT-mediated actin folding

K NEIRYNCKDavy WaterschootJoël VandekerckhoveChristophe AmpeHeidi Rommelaere

A1 Journal Article in JOURNAL OF MOLECULAR BIOLOGY

Caenorhabditis elegans expresses three functional profilins in a tissue-specific manner

Debby PoletAnja LambrechtsK ONOA MAHFrank PeelmanJoël VandekerckhoveDL BAILLIEChristophe AmpeS ONO

A1 Journal Article in CELL MOTILITY AND THE CYTOSKELETON

Cell_motility : a cross-platform, open source application for the study of cell motion paths

Lennart MartensGeert MonsieurChristophe AmpeKris GevaertJoël Vandekerckhove

A1 Journal Article in BMC BIOINFORMATICS

Identification of the PXW sequence as a structural gatekeeper of the headpiece C-terminal subdomain fold

Wim VermeulenMarleen Van TroysDavid BourryDaisy DewitteStefaan RossenuMarc GoethalsFrans BorremansJoël VandekerckhoveJosé MartinsChristophe Ampe

A1 Journal Article in JOURNAL OF MOLECULAR BIOLOGY

Multirepeat beta-thymosins

Marleen Van TroysStien DhaeseJoël VandekerckhoveChristophe Ampe

Bookchapter in Actin-Monomer-Binding Proteins

Profilin-I-ligand interactions influence various aspects of neuronal differentiation

Anja LambrechtsVeronique JonckheereC PELEMANDebby PoletWinnok De VosJoël VandekerckhoveChristophe Ampe

A1 Journal Article in JOURNAL OF CELL SCIENCE

THE ROLE OF PRO62 AND TRP64 FOR HEADPIECE STABILITY

David BourryW VERMEULENMarleen Van TroysD DEWITTES ROSSENUMarc GoethalsFrans BorremansJoël VandekerckhoveJosé MartinsChristophe Ampe

The Role of Pro62 and Trp64 for HeadPiece Stability

David BourryW VERMEULENMarleen Van TroysMarc GoethalsFrans BorremansJoël VandekerckhoveChristophe AmpeJosé Martins

Tobacco WLIM1 is a novel F-actin binding protein involved in actin cytoskeleton remodeling

Clément ThomasCéline HoffmannMonika DieterleMarleen Van TroysChristophe AmpeAndré Steinmetz

A1 Journal Article in PLANT CELL

2005

A role for complexes of survival of motor neurons (SNM) protein with gemins and profilin in neurite-like cytoplasmic extensions of cultured nerve cells

A SHARMAAnja LambrechtsLT HAOTT LECA SEWRYChristophe AmpeAHM BURGHESGE MORRIS

A1 Journal Article in EXPERIMENTAL CELL RESEARCH

Actin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement

A GIGANTIJ PLASTINOB JANJIMarleen Van TroysD LENTZChristophe AmpeC SYKESE FRIEDERICH

A1 Journal Article in JOURNAL OF CELL SCIENCE

NMR study of the headpiece domain : structure-function and structure-stability correlations

Wim VermeulenJosé MartinsFrans BorremansChristophe Ampe

Reducing mutational bias in random protein libraries

Thomas VanherckeChristophe AmpeLuc TirryP DENOLF

A1 Journal Article in ANALYTICAL BIOCHEMISTRY

Rescue and in situ selection and evaluation (RISE): A method for high-throughput panning of phage display libraries

Thomas VanherckeChristophe AmpeLuc TirryP DENOLF

A1 Journal Article in JOURNAL OF BIOMOLECULAR SCREENING

2004

Myopathy mutations in alpha-skeletal-muscle actin cause a range of molecular defects

CF COSTAHeidi RommelaereDavy WaterschootKK SETHIKJ NOWAKNG LAINGChristophe AmpeLM MACHESKY

A1 Journal Article in JOURNAL OF CELL SCIENCE

STRUCTURE, FUNCTION AND FOLD STABILITY OF THE HEADPIECE C-TERMINAL SUBDOMAIN

W VERMEULENDavid BourryP VANHAESEBROUCKMarc GoethalsChristophe AmpeFrans BorremansJosé Martins

Selective contribution of eukaryotic prefoldin subunits to actin and tubulin binding

CT SIMONSAn StaesHeidi RommelaereChristophe AmpeSA LEWISNJ COWAN

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Solution structures of the C-terminal headpiece subdomains of human villin and advillin, evaluation of headpiece F-actin-binding requirements

Wim VermeulenPeter VanhaesebrouckMarleen Van TroysM VERSCHUERENFranky FantMarc GoethalsChristophe AmpeJosé MartinsFrans Borremans

A1 Journal Article in PROTEIN SCIENCE

Structural plasticity of functional actin: Pictures of actin binding protein and polymer interfaces (vol 11, pg 1279, 2004)

Heidi RommelaereDavy WaterschootK NEIRYNCKJoël VandekerckhoveChristophe Ampe

TetraThymosin beta is required for actin dynamics in Caenorhabditis elegans and acts via functionally different actin-binding repeats

Marleen Van TroysK ONODaisy DewitteVeronique JonckheereNatalie De RuyckJoël VandekerckhoveS ONOChristophe Ampe

A1 Journal Article in MOLECULAR BIOLOGY OF THE CELL

The actin cytoskeleton in normal and pathological cell motility

Anja LambrechtsMarleen Van TroysChristophe Ampe

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The folding pathways of actin and tubulins, mechanism of and recognition by the eukaryotic chaperones prefoldin and CCT

Katrien NeirynckHeidi RommelaereJoël VandekerckhoveChristophe Ampe

A2 Journal Article in Recent Res. Mol. Cell. Biol.

2003

A phage display-based method for determination of relative affinities of mutants - Application to the actin-binding motifs in thymosin beta 4 and the villin headpiece

S ROSSENUShirley LeymanDaisy DewitteDanny PeelaersVeronique JonckheereMarleen Van TroysJoël VandekerckhoveChristophe Ampe

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Structural plasticity of functional actin: Pictures of actin binding protein and polymer interfaces

Heidi RommelaereDavy WaterschootKatrien NeirynckJoël VandekerckhoveChristophe Ampe

A1 Journal Article in STRUCTURE

2002

Mutational analysis of human profilin I reveals a second PI(4,5)-P2 binding site neighbouring the poly(L-proline) binding site

Anja LambrechtsVeronique JonckheereDaisy DewitteJoël VandekerckhoveChristophe Ampe

A1 Journal Article in BMC BIOCHEMISTRY

Normalization of nomenclature for peptide motifs as ligands of modular protein domains.

R AASLANDC ABRAMSChristophe AmpeLJ BALLMT BEDFORDG CESARENIM GIMONAJH HURLEYT JARCHAUVP LEHTO et al.

A1 Journal Article in FEBS LETTERS

2001

Actin and actin filaments

Christophe AmpeJoël Vandekerckhove

2000

Profilin II is alternatively spliced, resulting in profilin isoforms that are differentially expressed and have distinct biochemical properties

Anja LambrechtsAttila BraunVeronique JonckheereAttila AszodiLorene M LanierJohan RobbensInge Van ColenJoël VandekerckhoveReinhard FässlerChristophe Ampe

A1 Journal Article in MOLECULAR AND CELLULAR BIOLOGY

Structural requirements for thymosin beta 4 in its contact with actin - An NMR-analysis of thymosin beta 4 mutants in solution and correlation with their biological activity.

C SIMENELMarleen Van TroysJoël VandekerckhoveChristophe AmpeM DELEPIERRE

A1 Journal Article in EUROPEAN JOURNAL OF BIOCHEMISTRY

The competitive interaction of actin and PIP2 with actophorin is based on overlapping target sites : design of a gain-of-function mutant

Marleen Van TroysDaisy DewitteJean-Luc VerscheldeMarc GoethalsJoël VandekerckhoveChristophe Ampe

A1 Journal Article in BIOCHEMISTRY

cAMP-dependent protein kinase phosphorylation of EVL, a mena/VASP relative, regulates its interaction with actin and SH3 domains.

Anja LambrechtsAV KWIATKOWSKILM LANIERJE BEARJoël VandekerckhoveChristophe AmpeFB GERTLER

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

1999

Dimerization of profilin II upon binding the (GP(5))(3) peptide from VASP overcomes the inhibition of actin nucleation by profilin II and thymosin beta 4.

V JONCKHEEREAnja LambrechtsJoël VandekerckhoveChristophe Ampe

A1 Journal Article in FEBS LETTERS

Effects of natural mutations in lecithin:cholesterol acyltransferase on the enzyme structure and activity

Frank PeelmanJean-Luc VerscheldeBerlinda VanlooChristophe AmpeChristine LabeurJan TavernierJoël VandekerckhoveMaryvonne Rosseneu

A1 Journal Article in JOURNAL OF LIPID RESEARCH

Structural modules in actin binding proteins: towards a new classification.

Marleen Van TroysJoël VandekerckhoveChristophe Ampe

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The cytosolic class II chaperonin CCT recognizes delineated hydrophobic sequences in its target proteins

Heidi RommelaereMyriam De NeveRonald MelkiJoël VandekerckhoveChristophe Ampe

A1 Journal Article in BIOCHEMISTRY

1998

Analysis of three human interleukin 5 structures suggests a possible receptor binding mechanism.

JL VERSCHELDEChristophe AmpeYves GuisezC OEFNERJoël VandekerckhoveJan Tavernier

A1 Journal Article in FEBS LETTERS

Identification of cofilin, coronin, Rac and capZ in actin tails using a Listeria affinity approach.

V DAVIDE GOUINM VAN TROYSA GROGANAW SEGALChristophe AmpeP COSSART

A1 Journal Article in JOURNAL OF CELL SCIENCE

Murine adseverin (D5), a novel member of the gelsolin family, and murine adseverin are induced by interleukin-9 in T-helper lymphocytes

Johan RobbensJamila LouahedKathleen De PestelInge Van ColenChristophe AmpeJoël VandekerckhoveJean-Christophe Renauld

A1 Journal Article in MOLECULAR AND CELLULAR BIOLOGY

Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin.

IE VAINBERGSA LEWISH ROMMELAEREChristophe AmpeJoël VandekerckhoveHL KLEINNJ COWAN

A1 Journal Article in CELL

1997

A phage display technique for a fast, sensitive, and systematic investigation of protein-protein interactions.

Stefaan RossenuD DEWITTEJoël VandekerckhoveChristophe Ampe

A1 Journal Article in JOURNAL OF PROTEIN CHEMISTRY

Analogous F-actin binding by cofilin and gelsolin segment 2 substantiates their structural relationship

Marleen Van TroysDaisy DewitteJean-Luc VerscheldeMark GoethalsJoël VandekerckhoveChristophe Ampe

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

The mammalian profilin isoforms display complementary affinities for PIP2 and proline-rich sequences.

Anja LambrechtsJean-Luc VerscheldeV JONCKHEEREM GOETHALSJoël VandekerckhoveChristophe Ampe

A1 Journal Article in EMBO JOURNAL

Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors.

GL TIANSA LEWISB FEIERBACHT STEARNSHeidi RommelaereChristophe AmpeNJ COWAN

A1 Journal Article in JOURNAL OF CELL BIOLOGY

1996

Cofactor A is a molecular chaperone required for β-tubulin folding : functional and structural characterization

Ronald MelkiHeidi RommelaereRobin LeguyJoël VandekerckhoveChristophe Ampe

A1 Journal Article in BIOCHEMISTRY

Detailed quantitative analysis of the actin-binding site of the actin-sequestering protein thymosin beta 4.

M VANTROYSD DEWITTEM GOETHALSMF CARLIERJoël VandekerckhoveChristophe Ampe

A1 Journal Article in ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Differential binding of ligands to bovine profilin isoforms.

Anja LambrechtsJL VERSCHELDEV JONCKHEEREM GOETHALSJoël VandekerckhoveChristophe Ampe

A1 Journal Article in ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Evidence for an actin binding helix in gelsolin segment 2; Have homologous sequences in segments 1 and 2 of gelsolin evolved to divergent actin binding functions?

M VANTROYSD DEWITTEM GOETHALSJoël VandekerckhoveChristophe Ampe

A1 Journal Article in FEBS LETTERS

Pathway leading to correctly folded beta-tubulin.

GL TIANY HUANGHeidi RommelaereJoël VandekerckhoveChristophe AmpeNJ COWAN

A1 Journal Article in CELL

The actin binding site of thymosin beta 4 mapped by mutational analysis

M VantroysD DewitteM GoethalsMF CarlierJoël VandekerckhoveChristophe Ampe

A1 Journal Article in EMBO JOURNAL

1995

PURIFICATION AND CHARACTERIZATION OF BOVINE PROFILIN .2. ACTIN, POLY(L-PROLINE) AND INOSITOLPHOSPHOLIPID BINDING.

Anja LambrechtsJ VANDAMMEM GOETHALSJoël VandekerckhoveChristophe Ampe

A1 Journal Article in EUROPEAN JOURNAL OF BIOCHEMISTRY

Purification and characterization of bovine profilin II. Actin, poly (L-proline) and inositolphospholipid binding

Anja LambrechtsJozef Van DammeM GOETHALSJoël VandekerckhoveChristophe Ampe

A2 Journal Article in Eur. J. Biochem., 230, 281-286

1994

A novel cochaperonin that modulates the ATPases activity of cytoplasmic chaperonin.

Y GAOPD WALDENSA LEWISChristophe AmpeHeidi RommelaereJoël VandekerckhoveNJ COWANR MELKI

A1 Journal Article in JOURNAL OF CELL BIOLOGY

Actin-actin binding protein interfaces

Christophe AmpeJoël Vandekerckhove

A2 Journal Article in SEMINARS IN CELL BIOLOGY

Purification of a cortical complex containing 2 unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose.

LM MACHESKYSJ ATKINSONChristophe AmpeJoël VandekerckhoveTD POLLARD

A1 Journal Article in JOURNAL OF CELL BIOLOGY

Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose

L MACHESKYSJ ATKINSONChristophe AmpeJoël VandekerckhoveTD POLLARD

A2 Journal Article in Journal Cell Biol., 127, 107-115

1993

EUKARYOTIC CYTOSOLIC CHAPERONIN CONTAINS T-COMPLEX POLYPEPTIDE-1 AND 7 RELATED SUBUNITS.

H ROMMELAEREM VANTROYSYJ GAOR MELKINJ COWANJoël VandekerckhoveChristophe Ampe

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eukaryotic cytosolic chaperonin contains t-complex polypeptide 1 and seven related subunits

M ROMMELAEREH VAN TROYSY GAOR MELKINJ COWANJoël VandekerckhoveChristophe Ampe

Functional and chemical characterization of Hymenoptaecin, an antibacterial polypeptide that is infection-inducible in the honeybee (Apis mellifera)

Peter CasteelsChristophe AmpeFranciscus JacobsPaul Tempst

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Primary structure of and studies on Acanthamoeba actophorin

Stephen QuirkSutherland K MaciverChristophe AmpeStephen K DobersteinDonald A KaiserJozef Van DammeJoël VandekerckhoveThomas D Pollard

A1 Journal Article in BIOCHEMISTRY

1991

DNA-induced increase in the α-helical content of C/EBP and GCN4

Karyn T O'NeilJon D ShumanChristophe AmpeWilliam F DeGrado

A1 Journal Article in BIOCHEMISTRY

1990

Fragments of the HIV-1 Tat protein specifically bind TAR RNA

Kevin M WeeksChristophe AmpeSteve C SchultzThomas A SteitzDonald M Crothers

A1 Journal Article in SCIENCE

Isolation and characterization of abaecin, a major antibacterial response peptide in the honeybee (Apis mellifera)

Peter CasteelsChristophe AmpeLise RivièreJosé Van DammeChristopher EliconeMark FlemingFranciscus JacobsPaul Tempst

A1 Journal Article in EUROPEAN JOURNAL OF BIOCHEMISTRY

Molecular characterization of the GCN4-DNA complex

Marc R GartenbergChristophe AmpeThomas A SteitzDonald M Crothers

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

1989

Apidaecins : antibacterial peptides from honeybees

Peter CasteelsChristophe AmpeFranciscus JacobsMark VaeckPaul Tempst

A1 Journal Article in EMBO JOURNAL

Single active-site histidine in D-xylose isomerase from Streptomyces violaceoruber: identification by chemical derivatization and peptide mapping

Werner VangrysperreChristophe AmpeHilda Kersters-HildersonPaul Tempst

A1 Journal Article in BIOCHEMICAL JOURNAL

1988

Gemeenschappelijke domeinen in actine-bindende eiwitten; de primaire structuur van Acanthamoeba profilin-I en -II, kalfsmilt en menselijk bloedplaatjes profilin, Physarum fragmin, CAP42(a) en CAP42(b)

Christophe AmpeJ. VandekerckhoveM. Van Montagu

The primary structure of human platelet profilin: reinvestigation of the calf spleen profilin sequence

Christophe AmpeFrancis MarkeyUno LindbergJoël Vandekerckhove

A1 Journal Article in FEBS LETTERS

The primary structure of the basic isoform of Acanthamoeba profilin

Christophe AmpeMasahiko SatoThomas D PollardJoël Vandekerckhove

A1 Journal Article in EUROPEAN JOURNAL OF BIOCHEMISTRY

1987

The F-actin capping proteins of Physarum polycephalum: cap42(a) is very similar, if not identical, to fragmin and is structurally and functionally very homologous to gelsolin ; cap42(b) is Physarum actin

Christophe AmpeJoël Vandekerckhove

A1 Journal Article in EMBO JOURNAL

The amino acid sequence of protein II and its phosphorylation site for protein kinase C; the domain structure Ca2+ modulated lipid binding proteins

Klaus WeberNils JohnssonUwe PlessmannPhuc Nguyen VanHans-Dieter SölingChristophe AmpeJoël Vandekerckhove

A1 Journal Article in EMBO JOURNAL

1986

Protein-chemical identification of the major cleavage sites of the Ca²⁺ proteinase on murine vimentin, the mesenchymal intermediate filament protein

Stefan FischerJoël VandekerckhoveChristophe AmpePeter TraubKlaus Weber

A1 Journal Article in BIOLOGICAL CHEMISTRY HOPPE-SEYLER

Structural and functional analysis of a cloned delta endotoxin of Bacillus thuringiensis berliner 1715

Herman HöfteHenri De GreveJef SeurinckStefan JansenJacques MahillonChristophe AmpeJoël VandekerckhoveHilde VanderbruggenMarc Van MontaguMarc Zabeau et al.

A1 Journal Article in EUROPEAN JOURNAL OF BIOCHEMISTRY

The amino-acid sequence of the 2S sulphur-rich proteins from seeds of Brazil nut (Bertholletia excelsa H.B.K.)

Christophe AmpeJozef Van DammeLuiz AB de CastroMaria José AM SampaioMarc Van MontaguJoël Vandekerckhove

A1 Journal Article in EUROPEAN JOURNAL OF BIOCHEMISTRY

1985

The amino acid sequence of Acanthamoeba profilin

Christophe AmpeJoël VandekerckhoveStephen L BrennerLarry TobacmanEdward D Korn

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Christophe AmpeJoël Vandekerckhove

Bookchapter in Guidebook to the Cytoskeletal and Motor Proteins, Eds. T. Kreis and R. Vale, 1999

Assaying binding and covalent modifications of cytoskeletal proteins

Christophe AmpeJoël Vandekerckhove

Bookchapter in The Cytoskeleton in Signalling and Cell Regulation : A Practical Approach / Eds. Carraway and Carraway. - 1999