Research Explorer

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Researcher

Charlotte Wallaeys

Publications & Research Data

Awards & Distinctions

18 Results

2025

A crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS

Louise NuyttensMarah HeyerickMaxime RoesElise MoensCéline Van DenderCharlotte WallaeysTino HochepiedSteven TimmermansJolien VandewalleClaude Libert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells

Steven TimmermansCharlotte WallaeysSomara De BeulNatalia Garcia GonzalezClaude Libert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line

Natalia Garcia GonzalezCharlotte WallaeysWendy ToussaintTino HochepiedSylviane DewaeleSomara De BeulRobin Van LokeJolien VandewalleSteven TimmermansRichard S. Blumberg et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2024

Identification and characterization of multiple Paneth cell types in the mouse small intestine

Steven TimmermansCharlotte WallaeysNatalia Garcia GonzalezLotte PollarisYvan SaeysClaude Libert

A1 Journal Article in CELLS

Paneth cell TNF signaling induces gut bacterial translocation and sepsis

Charlotte WallaeysNatalia Garcia GonzalezSteven TimmermansJolien VandewalleTineke VanderhaeghenSomara De BeulHester DufoorMelanie EggermontElise MoensVictor Bosteels et al.

A1 Journal Article in CELL HOST & MICROBE

2023

Exploring Paneth cells : uncovering their homeostatic diversity and role in TNF-induced SIRS

Charlotte WallaeysClaude Libert

Paneth cells as the cornerstones of intestinal and organismal health : a primer

Charlotte WallaeysNatalia Garcia GonzalezClaude Libert

A1 Journal Article in EMBO MOLECULAR MEDICINE

The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function

Tineke VanderhaeghenSteven TimmermansMelanie EggermontDeepika WattsJolien VandewalleCharlotte WallaeysLouise NuyttensJoyca De TemmermanTino HochepiedSylviane Dewaele et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2022

Reprogramming of glucocorticoid receptor function by hypoxia

Tineke VanderhaeghenSteven TimmermansDeepika WattsVille PaakinahoMelanie EggermontJolien VandewalleCharlotte WallaeysLise Van WyngeneKelly Van LooverenLouise Nuyttens et al.

A1 Journal Article in EMBO REPORTS

2021

Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis

Jolien VandewalleSteven TimmermansVille PaakinahoLies VancraeynestLiza DewyseTineke VanderhaeghenCharlotte WallaeysLise Van WyngeneKelly Van LooverenLouise Nuyttens et al.

A1 Journal Article in CELL METABOLISM

Turning a pathogen protein into a therapeutic tool for sepsis

Tineke VanderhaeghenCharlotte WallaeysClaude Libert

Editorial material

ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation

Lise Van WyngeneTineke VanderhaeghenIoanna PettaSteven TimmermansKatrien CorbeelsBart Van der SchuerenJolien VandewalleKelly Van LooverenCharlotte WallaeysMelanie Eggermont et al.

A1 Journal Article in ISCIENCE

2020

Adjuvanting allergen extracts for sublingual immunotherapy : calcitriol downregulates CXCL8 production in primary sublingual epithelial cells

Michael PelstClara HoebartCharlotte WallaeysHilde De RoosterYannick GansemansFilip Van NieuwerburghBert DevriendtEric Cox

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Glucocorticoids limit lipopolysaccharide-induced lethal inflammation by a double control system

Kelly Van LooverenSteven TimmermansTineke VanderhaeghenCharlotte WallaeysMarlies BallegeerJolien SouffriauMelanie EggermontJolien VandewalleLise Van WyngeneKarolien De Bosscher et al.

A1 Journal Article in EMBO REPORTS

Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis

Lise Van WyngeneTineke VanderhaeghenSteven TimmermansJolien VandewalleKelly Van LooverenJolien SouffriauCharlotte WallaeysMelanie EggermontSam ErnstEvelien Van Hamme et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

Potential of glucocorticoids to treat intestinal inflammation during sepsis

Kelly Van LooverenCharlotte WallaeysClaude Libert

A1 Journal Article in CURRENT OPINION IN PHARMACOLOGY

Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium

Jolien SouffriauSteven TimmermansTineke VanderhaeghenCharlotte WallaeysKelly Van LooverenLindsy AelbrechtSylviane DewaeleJolien VandewalleEvy GoossensSerge Verbanck et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

2018

Establishment of a cell culture of canine oral keratinocytes : alpha6 as a marker for positive selection

Michael PelstCharlotte WallaeysHilde De RoosterEric Cox