Research Explorer

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Researcher

Charlotte Debbaut

Awards & Distinctions

203 Results

2024

Branching exponents of synthetic vascular trees under different optimality principles

Etienne JessenMarc C. SteinbachCharlotte DebbautDominik Schillinger

A1 Journal Article in IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Effect of interstitial fluid pressure on shear wave elastography : an experimental and computational study

Ariana CihanKristýna HolkováLuxi WeiHendrik J VosCharlotte DebbautAnnette CaenenPatrick Segers

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

First‐in‐human real‐time AI‐assisted instrument deocclusion during augmented reality robotic surgery

Jasper HofmanPieter De BackerIlaria ManghiJente SimoensRuben De GrooteHannes Van Den BosscheMathieu D'HondtTim OosterlinckJulie LippensCharles Van Praet et al.

A2 Journal Article in HEALTHCARE TECHNOLOGY LETTERS

Hydraulic conductivity of human cancer tissue : a hybrid study

Hooman SalavatiPim PullensCharlotte DebbautWim Ceelen

A1 Journal Article in BIOENGINEERING & TRANSLATIONAL MEDICINE

Quantitative dynamic contrast-enhanced MRI : a gateway to personalized models of solid tumors

Hooman SalavatiWim CeelenCharlotte DebbautPim Pullens

Spatiotemporal analysis of particle spread to assess the hybrid particle-flow CFD model of radioembolization of HCC tumors

Tim BombernaSaar VermijsLawrence BonneChris VerslypeGeert MaleuxCharlotte Debbaut

A1 Journal Article in IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

2023

A novel three-dimensional planning tool for selective clamping during partial nephrectomy : validation of a perfusion zone algorithm

Pieter De BackerSaar VermijsCharles Van PraetPieter De VisschereSarah VandenbulckeAngelo MottaranCarlo A. BraviCamille BerquinEdward LambertStephanie Dautricourt et al.

A1 Journal Article in EUROPEAN UROLOGY

A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment

Elly De VlieghereKoen Van de VijverEva BlondeelNathan CarpentierRouba GhobeiraJarne PauwelsSebastian RiemannManon MinsartCharlotte FieuwsJohanna Mestach et al.

A1 Journal Article in BIOMATERIALS RESEARCH

Connecting the macro- and micro-scale properties in human solid tumors : hydraulic conductivity

Hooman SalavatiCharlotte DebbautPim PullensWim Ceelen

Drug transport modeling in solid tumors : a computational exploration of spatial heterogeneity of biophysical properties

Hooman SalavatiPim PullensWim CeelenCharlotte Debbaut

A1 Journal Article in COMPUTERS IN BIOLOGY AND MEDICINE

Improving augmented reality through deep learning : real-time instrument delineation in robotic renal surgery

Pieter De BackerCharles Van PraetJente SimoensMaria Peraire LoresHeleen CreemersKenzo MestdaghCharlotte AllaeysSaar VermijsPietro PiazzaAngelo Mottaran et al.

A1 Journal Article in EUROPEAN UROLOGY

Integrating DCE-MRI and IVIM-DWI in a computational simulation of interstitial fluid pressure in a pancreatic tumor

Hooman SalavatiWim CeelenCharlotte DebbautCLARISSE LECLUYSEPim Pullens

Interstitial fluid pressure in heterogenous solid tumors : a computational study

Hooman SalavatiPim PullensWim CeelenCharlotte Debbaut

Modelling lymph propulsion in a 3D model of murine collecting vessel with three lymphangions in series

Ghazal Adeli KoudehiCarlos Alejandro Silvera DelgadoMatthias Van ImpePieter CornillieChristophe CasteleynChristian VanhoveCharlotte DebbautPatrick Segers

A1 Journal Article in ARTERY RESEARCH

Patient-specific computational model of interstitial fluid flow in pancreatic cancer based on DCE- and DW-MRI

Hooman SalavatiWim CeelenCharlotte DebbautCLARISSE LECLUYSEPim Pullens

Peri-operative digital planning in robot-assisted partial nephrectomy : bridging the gap between artificial intelligence, augmented reality and surgical data science

Pieter De BackerKarel DecaesteckerCharlotte DebbautAlexandre Mottrie

Pre-operative partial nephrectomy planning : from four-phase CT-scan to 3D renal perfusion model

Saar VermijsPieter De BackerPieter De VisschereAlexandre MottrieCharles Van PraetKarel DecaesteckerCharlotte Debbaut

Robot-assisted partial nephrectomy using intra-arterial renal hypothermia for highly complex endophytic or hilar tumors : case series and description of surgical technique

Pieter De BackerJoris VangeneugdenCamille BerquinSaar VermijsPeter DekuyperAlexandre MottrieCharlotte DebbautThierry QuackelsCharles Van PraetKarel Decaestecker

A1 Journal Article in EUROPEAN UROLOGY OPEN SCIENCE

Shear wave elastography for assessing interstitial fluid pressure : an in silico study

Ariana CihanAnnette CaenenCharlotte DebbautPatrick Segers

Surgical phase duration in robot-assisted partial nephrectomy : a surgical data science exploration for clinical relevance

Pieter De BackerMaria Peraire LoresMeret DemuynckFederico PiramideJente SimoensTim OosterlinckWouter BogaertChi Victor ShanKarel Van RegemorterAube Wastyn et al.

A1 Journal Article in DIAGNOSTICS

Truncation strategies for personalized CFD models of selective liver radioembolization

Tim BombernaSaar VermijsChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

2022

A hybrid particle-flow CFD modeling approach in truncated hepatic arterial trees for liver radioembolization : a patient-specific case study

Tim BombernaSaar VermijsMaryse LejolyChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

A1 Journal Article in FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY

A personalized approach to model the interstitial fluid flow in solid tumors : the role of interstitium permeability

Hooman SalavatiWim CeelenPim PullensCharlotte Debbaut

A preoperative planning tool for lung segmentectomy procedures : a case study

Saar VermijsBram CornettePieter De BackerKarel DecaesteckerLiesbeth DesenderCharlotte Debbaut

Assessment of hepatic arterial hemodynamics with 4D flow MRI : in vitro analysis of motion and spatial resolution related error and in vivo feasibility study in 20 volunteers

Ivan P. DimovCyril TousNing LiMaxime BaratTim BombernaCharlotte DebbautNing JinGerald MoranAn TangGilles Soulez

A1 Journal Article in EUROPEAN RADIOLOGY

Biomechanical aspects of the normal and cancer-associated lymphatic system

Wim CeelenHooman SalavatiGhazal Adeli KoudehiCarlos Alejandro Silvera DelgadoPatrick SegersCharlotte Debbaut

Bookchapter in The lymphatic system in colorectal cancer : basic concepts, pathology, imaging, and treatment perspectives

Computational fluids dynamics to investigate the impact of injection timing and location on microsphere and microbubble distribution in a simplified hepatic arterial tree

Tim BombernaNathalie SaikaliRomaine KunstHadi MirgolbabaeeErik Groot JebbinkGeert MaleuxCharlotte Debbaut

Computational investigation of the effective forces on droplets during electrostatic precipitation pressurized intraperitoneal aerosol chemotherapy (ePIPAC)

Mohammad Rahimi GorjiCharlotte DebbautGhader GhorbaniaslSarah CosynsWouter WillaertWim Ceelen

Computational modelling of liver hemodynamics and intrahepatic particle transport

Charlotte DebbautTim Bomberna

Efficacy of additional electrostatic precipitation to intraperitoneal aerosolized chemotherapy in a realistically reconstructed human peritoneal cavity : a computational study

Mohammad Rahimi GorjiCharlotte DebbautGhader GhorbaniaslSarah CosynsWouter WillaertWim Ceelen

Electrostatic precipitation pressurized intraperitoneal aerosol chemotherapy in a realistically reconstructed human peritoneal cavity : computational modelling approach

Mohammad Rahimi GorjiCharlotte DebbautGhader GhorbaniaslSarah CosynsWouter WillaertWim Ceelen

Experiment-based 3D modelling of lymph uptake and transport.

Ghazal Adeli KoudehiCarlos Alejandro Silvera DelgadoMatthias Van ImpePieter CornillieChristophe CasteleynChristian VanhoveWinnok De VosMichael DavisCharlotte DebbautPatrick Segers

In silico modeling of regional droplet deposition during aerosolized intraperitoneal chemotherapy using a patient-inspired geometry

Mohammad Rahimi GorjiCharlotte DebbautGhader GhorbaniaslSarah CosynsWouter WillaertWim Ceelen

Influence of the peritoneal metastatic microenvironment on interstitial permeability

Hooman SalavatiCharlotte DebbautPim PullensWim Ceelen

Interstitial fluid pressure as an emerging biomarker in solid tumors

Hooman SalavatiCharlotte DebbautPim PullensWim Ceelen

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Interstitial permeability of human cancer tissue : an in vitro study

Hooman SalavatiCharlotte DebbautPim PullensWim Ceelen

Multicentric exploration of tool annotation in robotic surgery : lessons learned when starting a surgical artificial intelligence project

Pieter De BackerJennifer A. EckhoffJente SimoensDolores T. MuellerCharlotte AllaeysHeleen CreemersAmélie HallemeeschKenzo MestdaghCharles Van PraetCharlotte Debbaut et al.

A1 Journal Article in SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

Numerical modelling in support of locoregional drug delivery during transarterial therapies for liver cancer

Charlotte DebbautTim Bomberna

Bookchapter in Modelling of mass transport processes in biological media

Optimization of intraperitoneal aerosolized drug delivery using computational fluid dynamics (CFD) modeling

Mohammad Rahimi GorjiCharlotte DebbautGhader GhorbaniaslSarah CosynsWouter WillaertWim Ceelen

A1 Journal Article in SCIENTIFIC REPORTS

Preoperative planning of partial nephrectomy procedures based on kidney perfusion zones

Saar VermijsPieter De BackerPieter De VisschereCharles Van PraetKarel DecaesteckerCharlotte Debbaut

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) : combination of computational simulations and in vitro experiments

Mohammad Rahimi GorjiWim CeelenCharlotte DebbautGhader Ghorbaniasl

Rigorous mathematical optimization of synthetic hepatic vascular trees

Etienne JessenMarc C. SteinbachCharlotte DebbautDominik Schillinger

A1 Journal Article in JOURNAL OF THE ROYAL SOCIETY INTERFACE

Simulation of electrostatic precipitation pressurized intraperitoneal aerosol chemotherapy (ePIPAC) in a realistic human abdominal model

Mohammad Rahimi GorjiCharlotte DebbautGhader GhorbaniaslSarah CosynsWouter WillaertWim Ceelen

The future of preoperative planning for liver cancer : from CT-scan in the 20th century to computational model in the 21st century

Tim BombernaCharlotte Debbaut

The impact of catheter location on tumor dose distribution for liver cancer radioembolization

Tim BombernaSaar VermijsChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

The impact of hepatic arterial tree complexity on microparticle transport in computational fluids dynamics simulations of radioembolization for hepatocellular carcinoma

Tim BombernaSaar VermijsMaryse LejolyChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

The impact of injection timing, injection velocity and inflow waveform on microsphere transport during liver radioembolization

Tim BombernaSaar VermijsChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

The role of the microenvironment in the hydraulic conductivity of solid tumors

Hooman SalavatiCharlotte DebbautPim PullensWim Ceelen

Towards the biomimetic design of hollow fiber membrane bioreactors for bioartificial organs and tissue engineering : a micro-computed tomography (μCT) approach

Giuseppe Falvo D'Urso LabateThomas De SchryverFrancesco BainoCharlotte DebbautGionata FragomeniChiara Vitale-BrovaroneLuc Van HoorebekePatrick SegersMatthieu BooneGerardo Catapano

A1 Journal Article in JOURNAL OF MEMBRANE SCIENCE

2021

3D selective arterial clamping in robot assisted partial nephrectomy

Pieter De BackerSaar VermijsCharles Van PraetSarah VandenbulckeMaryse LejolyStefanie VanderscheldenPieter De VisschereAlexandre MottrieCharlotte DebbautKarel Decaestecker

A novel method for measuring the hydraulic conductivity of tumor tissue

Hooman SalavatiCharlotte DebbautPim PullensWim Ceelen

Aerosolization of thermosensitive hydrogels using pressurized intraperitoneal aerosol chemotherapy (PIPAC)

Mohammad Rahimi GorjiHelena BraetCharlotte DebbautGhader GhorbaniaslSarah CosynsWouter WillaertKatrien RemautWim Ceelen

Analysis of the effect of liquid viscosity on the aerosol distribution during Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) using computational modeling

Mohammad Rahimi GorjiSarah CosynsCharlotte DebbautGhader GhorbaniaslWouter WillaertWim Ceelen

Automated prediction of selective arterial clamping strategy in robot assisted partial nephrectomy

Pieter De BackerSaar VermijsRania MatthysRoberto CianiPieter De VisschereCharles Van PraetAlexandre MottrieCharlotte DebbautKarel Decaestecker

Calibration of an electrical analog model of liver hemodynamics in fontan patients

Elyar Abbasi BavilMatthew G. DoyleCharlotte DebbautRachel M. WaldLuc MertensThomas L. ForbesCristina H. Amon

A1 Journal Article in JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Comparing time-efficient particle release maps for liver tumor targeting with embolizing microparticles

Tim BombernaGeert MaleuxCharlotte Debbaut

Development of an interactive, patient-specific planning tool for partial nephrectomy procedures

Saar VermijsPieter De BackerRania MatthysRoberto CianiCharles Van PraetKarel DecaesteckerCharlotte Debbaut

Effect of fluid flow rate and droplet size on spatial aerosol distribution during pressurized intraperitoneal aerosol chemotherapy (PIPAC)

Mohammad Rahimi GorjiGhader GhorbaniaslSarah CosynsWouter WillaertWim CeelenCharlotte Debbaut

Electrostatic precipitation pressurized intraperitoneal aerosol chemotherapy (ePIPAC) : finding the optimal electrical potential

Mohammad Rahimi GorjiCharlotte DebbautGhader GhorbaniaslWouter WillaertSarah CosynsWim Ceelen

Evaluating the impact of catheter type on local hemodynamics to improve transarterial liver cancer treatments

Tim BombernaGhazal Adeli KoudehiChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

Ex-vivo renal vascular dominant region mapping using artery-selective contrast injections

Nathan SennesaelPieter De BackerKarel DecaesteckerPieter De VisschereMarijn SpeeckaertSaar VermijsGeert VilleirsCharlotte DebbautPim Pullens

Exploring high pressure nebulization of pluronic F127 hydrogels for intraperitoneal drug delivery

Helena BraetMohammad Rahimi GorjiCharlotte DebbautG GhorbaniaslThibault Van WalleghemSenne CornelisSarah CosynsChris VervaetWouter WillaertWim Ceelen et al.

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

In vitro study of aerosol droplet impact on the peritoneal surface after nebulization using the CapnoPen device

Mohammad Rahimi GorjiStéphane DorboloSarah CosynsCharlotte DebbautGhader GhorbaniaslWouter WillaertWim Ceelen

Interstitial fluid pressure and hydraulic conductivity in solid tumors : introducing an in-vitro method for measuring the hydraulic conductivity of tumor tissue

Hooman SalavatiCharlotte DebbautPim PullensWim Ceelen

Modelling lymph propulsion in a 3D reconstructed murine collecting vessel with 3 lymphangions in series

Ghazal Adeli KoudehiCarlos Alejandro Silvera DelgadoMatthias Van ImpePieter CornillieChristophe CasteleynChristian VanhoveCharlotte DebbautPatrick Segers

Modelling lymph uptake from the interstitium into the lymphatic system in the true morphology of a murine dermal network of terminal lymphatics

Ghazal Adeli KoudehiPieter CornillieChristophe CasteleynWinnok De VosCharlotte DebbautPatrick SegersMichael Davis

Numerical simulations of pressurized intraperitoneal aerosol chemotherapy (PIPAC) : effect of inertial impaction

Mohammad Rahimi GorjiCharlotte DebbautGhader GhorbaniaslWouter WillaertWim Ceelen

Parametric sensitivity analysis of lymph flow in a 3D reconstructed murine collecting vessel with 3 lymphangions in series

Ghazal Adeli KoudehiCarlos Alejandro Silvera DelgadoMatthias Van ImpePieter CornillieChristophe CasteleynChristian VanhoveCharlotte DebbautPatrick Segers

Point-of-care 3D printing : a low-cost approach to teaching carotid artery stenting

Pieter De BackerCharlotte AllaeysCharlotte DebbautRoel Beelen

A2 Journal Article in 3D PRINTING IN MEDICINE

Proof-of-concept CFD model to improve hepatic arterial tree recellularization protocols

Tim BombernaGhazal Adeli KoudehiPedro BaptistaCharlotte Debbaut

Resistance to intraperitoneal drug delivery and heterogeneity of peritoneal metastasis : the role of hydraulic conductivity

Hooman SalavatiCharlotte DebbautPim PullensWim Ceelen

The effect of a necrotic core on the interstitial fluid pressure in solid tumors

Hooman SalavatiPim PullensWim CeelenCharlotte Debbaut

The impact of injection timing and location on microparticle delivery for tumor targeting in a patient-specific liver

Tim BombernaChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

Transarterial drug delivery for liver cancer : numerical simulations and experimental validation of particle distribution in patient-specific livers

Tim BombernaGhazal Adeli KoudehiCharlotte ClaereboutChris VerslypeGeert MaleuxCharlotte Debbaut

A1 Journal Article in EXPERT OPINION ON DRUG DELIVERY

2020

A numerical simulation of pressurized intraperitoneal aerosol chemotherapy (PIPAC) : validation part

Mohammad Rahimi GorjiCharlotte DebbautWouter WillaertPatrick SegersGhader GhorbaniaslWim Ceelen

Biomechanical comparison of Thiel embalmed and fresh frozen nerve tissue

Michael StouthandelChristian VanhoveWouter DevriendtSander De BockCharlotte DebbautCarl VangestelTom Van Hoof

A1 Journal Article in ANATOMICAL SCIENCE INTERNATIONAL

Computational fluid dynamics as a tool for patient-specific injection planning of transarterial therapies for hepatocellular carcinoma

Tim BombernaChris VerslypeGeert MaleuxCharlotte Debbaut

Effects of electrostatic precipitation on IP drug distribution and tissue penetration of nanoparticles

Mohammad Rahimi GorjiLeen Van de SandeCharlotte DebbautGhader GhorbaniaslWouter WillaertSarah CosynsWim Ceelen

Electrostatic intraperitoneal aerosol delivery of nanoparticles : proof of concept and preclinical validation

Leen Van de SandeMohammad Rahimi GorjiSilvia GiordanoEnrico DavoliCristina MatteoSonke DetlefsenKatharina D'HerdeHelena BraetMolood ShariatiKatrien Remaut et al.

A1 Journal Article in ADVANCED HEALTHCARE MATERIALS

In-vitro quantification of mechanical properties of peritoneal metastases

Hooman SalavatiNecla Kurt YusufCharlotte DebbautWim Ceelen

Intraperitoneal aerosolized drug delivery : technology, recent developments, and future outlook

Mohammad Rahimi GorjiLeen Van de SandeCharlotte DebbautGhader GhorbaniaslHelena BraetSarah CosynsKatrien RemautWouter WillaertWim Ceelen

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

Locoregional drug delivery for liver cancer : the impact of tumor burden on the particle distribution in a patient-specific liver

Tim BombernaGhazal Adeli KoudehiGeert MaleuxCharlotte Debbaut

Modelling lymph propulsion in a 3D reconstructed murine collecting vessel

Ghazal Adeli KoudehiCarlos Alejandro Silvera DelgadoMatthias Van ImpePieter CornillieChristophe CasteleynChristian VanhoveCharlotte DebbautPatrick Segers

Modelling lymph propulsion in a series of contracting lymphangions : from idealized 2D to reconstructed 3D

Ghazal Adeli KoudehiMatthias Van ImpePieter CornillieChristophe CasteleynChristian VanhoveCharlotte DebbautPatrick Segers

Nebulization of thermosensitive hydrogels to treat peritoneal carcinomatosis

Helena BraetMohammad Rahimi GorjiCharlotte DebbautWim CeelenStefaan De SmedtKatrien Remaut

Numerical modeling of interstitial fluid pressure in solid tumors : the importance of the lymphatic system

Hooman SalavatiWim CeelenCharlotte Debbaut

Targeted drug delivery for liver cancer : can we steer microparticles towards tumor tissue?

Tim BombernaGhazal Adeli KoudehiPatrick SegersCharlotte Debbaut

Targeted drug delivery for liver cancer : modelling the impact of cancer burden on the particle distribution

Tim BombernaGhazal Adeli KoudehiPatrick SegersCharlotte Debbaut

Using the venous angle as a pressure reservoir to retrogradely fill the subclavian lymphatic trunk with contrast agent for lymphatic mapping

Michael StouthandelCharlotte DebbautJurgen DevicheBart TruyensLiv VeldemanTom Van Hoof

A1 Journal Article in ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

2019

A 2D axisymmetric computational model for the study of mass transport into lymphatic capillaries and pre-collector vessels

Carlos Alejandro Silvera DelgadoGhazal Adeli KoudehiMatthias Van ImpeCharlotte DebbautPatrick Segers

A 2D axisymmetric computational model for the study of mass transport into lymphatic capillaries and pre-collector vessels

Carlos Alejandro Silvera DelgadoGhazal Adeli KoudehiMatthias Van ImpeCharlotte DebbautPatrick Segers

A 3D CFD model of the interstitial fluid pressure and drug distribution in heterogeneous tumor nodules during intraperitoneal chemotherapy

Margo SteuperaertCharlotte DebbautCharlotte CarlierOlivier De WeverBenedicte DescampsChristian VanhoveWim CeelenPatrick Segers

A1 Journal Article in DRUG DELIVERY

A numerical simulation of pressurized intraperitoneal aerosol chemotherapy (PIPAC) : validation part

Mohammad Rahimi GorjiCharlotte DebbautWouter WillaertPatrick SegersGhader GhorbaniaslWim Ceelen

Acquiring 3D morphological data of the lymphatic system in healthy mice: a feasibility study

Ghazal Adeli KoudehiBenedicte DescampsChristian VanhoveCharlotte DebbautChristophe CasteleynPieter CornilliePatrick Segers

Angiopoietin-2 promotes pathological angiogenesis and is a therapeutic target in murine nonalcoholic fatty liver disease

Sander LefereFrederique Van de VeldeAnne HoorensSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytBert VandeghinsteChristian VanhoveCharlotte Debbaut et al.

A1 Journal Article in HEPATOLOGY

Computational fluid dynamics model of pressurized intraperitoneal aerosol chemotherapy : gravity matters!

Mohammad Rahimi GorjiLeen Van de SandeCharlotte DebbautPatrick SegersWouter WillaertWim Ceelen

Computational model of pressurized intraperitoneal chemotherapy (PIPAC) for carcinomatosis treatment

Mohammad Rahimi GorjiCharlotte DebbautLeen Van de SandeWouter WillaertPatrick SegersWim Ceelen

Development of a planning tool for robot-assisted partial nephrectomy surgery based on 3D reconstructions of kidneys

Sarah VandenbulckePieter De BackerDanilo BabinPatrick SegersKarel DecaesteckerCharlotte Debbaut

Development of a planning tool for robot-assisted partial nephrectomy surgery based on 3D reconstructions of kidneys

Sarah VandenbulckePieter De BackerDanilo BabinPatrick SegersKarel DecaesteckerCharlotte Debbaut

Modeling of drug delivery and transport during intraperitoneal chemotherapy

Margo SteuperaertPatrick SegersWim CeelenCharlotte Debbaut

Modelling lymph propulsion in a series of contracting lymphangions immersed in the interstitium

Ghazal Adeli KoudehiMatthias Van ImpeCarlos Alejandro Silvera DelgadoChristophe CasteleynPieter CornillieCharlotte DebbautPatrick Segers

Modelling lymph propulsion in a series of pumping lymphangions

Ghazal Adeli KoudehiMatthias Van ImpeCarlos Alejandro Silvera DelgadoCharlotte DebbautChristophe CasteleynPieter CornilliePatrick Segers

Modelling of the vascular accessibility of human brain regions using 7T MRI

Jolan HeysePieter van MierloCharlotte DebbautVincent Keereman

Targeted drug delivery for liver cancer : the impact of cancer burden on the particle distribution in a patient-specific geometry

Tim BombernaGhazal Adeli KoudehiPatrick SegersCharlotte Debbaut

The pleural mesothelium and TGF-β1 pathways in restrictive allograft syndrome : a pre-clinical investigation

Annelore SacreasJan H. von der ThüsenThierry P. P. van den BoschBirgit WeynandErik K. VerbekenCharlotte DebbautDirk E. Van RaemdonckRobin VosStijn E. Verleden

A1 Journal Article in JOURNAL OF HEART AND LUNG TRANSPLANTATION

Validation of a computational fluid dynamics model of drug delivery and interstitial fluid pressure in ovarian cancer xenografts

Mohammad Rahimi GorjiSusmita BasakCharlotte DebbautBenedicte DescampsPim PullensPatrick SegersSteven SourbronWim Ceelen

Virtual clamping tool for RAPN

Pieter De BackerSarah VandenbulckeMaryse LejolyStefanie VanderscheldenCharles Van PraetDanilo BabinCharlotte DebbautKarel Decaestecker

2018

3D COMPUTATIONAL MODEL OF THE DRUG PARTICLE TRANSPORT DURING TARGETED DRUG DELIVERY FOR LIVER CANCER

Charlotte DebbautGhazal Adeli KoudehiPatrick Segers

Angiopoietin-2 promotes pathological angiogenesis and is a novel therapeutic target in non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeAnne HoorensSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytBert VandeghinsteChristian VanhoveCharlotte Debbaut et al.

CFD model of the interstitial fluid pressure (IFP) in realistic tumor geometries of peritoneal metastases from ovarian cancer

Mohammad Rahimi GorjiCharlotte DebbautMargo SteuperaertChristian VanhovePatrick SegersWim Ceelen

Closed-loop lumped parameter modelling of hemodynamics during cirrhogenesis in rats

Chloe AudebertGeert PeetersPatrick SegersWim LalemanDiethard MonbaliuHannelie KorfJonel TrebickaIrene Vignon-ClementelCharlotte Debbaut

A1 Journal Article in IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Computational Model for Non-invasive Prediction of Portal Pressure Gradient in Fontan Patients

Elyar Abbasi BaviMatthew G. DoyleCharlotte DebbautLuc MertensCristina H. Amon

Computational model of the drug particle transport during transarterial therapy for targeted drug delivery to liver tumors

Charlotte DebbautGhazal Adeli KoudehiPatrick Segers

Modeling lymphatic transport: a computational model of a contracting lymphangion

Matthias Van ImpeGhazal Adeli KoudehiCarlos Alejandro Silvera DelgadoCharlotte DebbautPatrick Segers

Modeling the interaction between the lymphatic capillaries and the interstitium in normal and lymphedema conditions

Ghazal Adeli KoudehiCarlos Alejandro Silvera DelgadoMatthias Van ImpeCharlotte DebbautChristophe CasteleynPieter CornilliePatrick Segers

Modelling the drug particle transport during transarterial drug delivery for liver cancer : a feasibility study

Charlotte DebbautGhazal Adeli KoudehiPatrick Segers

Numerical model of the drug carrier transport during targeted drug delivery for liver cancer : a feasibility study

Charlotte DebbautGhazal Adeli KoudehiPatrick Segers

Quantitative analysis of hepatic macro- and microvascular alterations during cirrhogenesis in the rat

Geert PeetersCharlotte DebbautAdrian FriebelPieter CornillieWinnok De VosKasper FavereIngrid Vander ElstTim VandecasteeleTim JohannLuc Van Hoorebeke et al.

A1 Journal Article in JOURNAL OF ANATOMY

2017

A multilevel framework to reconstruct anatomical 3D models of the hepatic vasculature in rat livers

Geert PeetersCharlotte DebbautWim LalemanDiethard MonbaliuIngrid Vander ElstJan R. DetrezTim VandecasteeleThomas De SchryverLuc Van HoorebekeKasper Favere et al.

A1 Journal Article in JOURNAL OF ANATOMY

Computational modeling of the lymphatic uptake

Ghazal Adeli KoudehiCarlos Alejandro Silvera DelgadoCharlotte DebbautChristophe CasteleynPieter CornilliePatrick Segers

Estimation of the permeability tensor of the microvasculature of the liver through fabric tensors

Rodrigo MorenoPatrick SegersCharlotte Debbaut

Bookchapter in Computational biomechanics for medicine

Mathematical modeling of intraperitoneal drug delivery : simulation of drug distribution in a single tumor nodule

Margo SteuperaertGiuseppe Falvo D'Urso LabateCharlotte DebbautOlivier De WeverChristian VanhoveWim CeelenPatrick Segers

A1 Journal Article in DRUG DELIVERY

Modelling drug transport during intraperitoneal chemotherapy

Margo SteuperaertCharlotte DebbautPatrick SegersWim Ceelen

A2 Journal Article in PLEURA AND PERITONEUM

Modelling the degenerative adaptation of the liver vasculature and perfusion in Cirrhosis

Geert PeetersPatrick SegersCharlotte DebbautWim Laleman

Multi-level modelling of angioarchitectural alterations during liver cirrhogenesis in rats

Charlotte DebbautGeert PeetersDiethard MonbaliuWim LalemanPatrick Segers

Vascular morphology alterations during liver cirrhogenesis in rats

Geert PeetersCharlotte DebbautWinnok De VosPieter CornillieThomas De SchryverDiethard MonbaliuWim LalemanPatrick Segers

2016

2D Transport model of radial packed-bed bioreactors for bone TE predicts that radial flux uniformity controls O2 distribution in cell activity-dependent fashion

Danilo DonatoGiuseppe Falvo D'Urso LabateCharlotte DebbautPatrick SegersGerardo Catapano

A multilevel framework to reconstruct anatomical 3D models of the hepatic vasculature in rat livers

Geert PeetersCharlotte DebbautWim LalemanDiethard MonbaliuJan R DetrezTim VandecasteeleThomas De SchryverKasper FavereJonas VerbekePieter Cornillie et al.

A multilevel framework to study the adaptive vascular morphology during liver cirrhogenesis

Geert PeetersCharlotte DebbautPascal VerdonckWim LalemanPatrick Segers

A multilevel framework to study the altering hepatic circulation in cirrhotic rats

Geert PeetersCharlotte DebbautPieter CornillieWinnok De VosThomas De SchryverDiethard MonbaliuWim LalemanPatrick Segers

A multiscale framework for studying vascular morphology alterations during liver cirrhogenesis : a feasibility study

Geert PeetersCharlotte DebbautWinnok De VosPieter CornillieJan DetrezTim VandecasteeleThomas De SchryverDiethard MonbaliuWim LalemanPatrick Segers

Automated 3D reconstruction of the normal and cirrhotic rat hepatic microvasculature using confocal microscopy: a feasibility study

Geert PeetersCharlotte DebbautJan DetrezWinnok De VosDiethard MonbaliuWim LalemanPatrick Segers

CHARACTERIZATION OF CELL SCAFFOLDING PROPERTIES OF HOLLOW FIBER MEMBRANE BIOREACTORS (HFMBS) FOR BONE TISSUE ENGINEERING BY MICROCOMPUTED TOMOGRAPHY

Giuseppe Falvo D'Urso LabateCharlotte DebbautFrancesco BainoLuc Van HoorebekeThomas De SchryverChiara Vitale-BrovaronePatrick SegersGerardo Catapano

Estimation of the Permeability Tensor of the Microvasculature of the Liver through Fabric Tensors

Rodrigo MorenoPatrick SegersCharlotte Debbaut

Imaging and modeling the blood circulation through the liver and kidney

Charlotte DebbautDiethard MonbaliuGeert PeetersPatrick Segers

MODEL-PREDICTED EFFECT OF CELL PROLIFERATION AND DIFFERENTIATION ON THE DARCY PERMEABILITY AND PERFUSION PATTERN OF ANNULAR POROUS CONSTRUCTS CULTURED IN rPBBs FOR BONE TISSUE ENGINEERING

Giuseppe Falvo D'Urso LabateFrancesco TorchiaCharlotte DebbautPatrick SegersGerardo Catapano

Mathematical Modeling of Drug Transport during Intraperitoneal Chemotherapy

Margo SteuperaertGiuseppe Falve D'Urso LabateCharlotte DebbautWim CeelenPatrick Segers

Microcomputed tomography (MCT) study of hollow fiber membrane (HFM) distribution in HFM-bioreactors in shell-and-tube configuration for bone TE

Giuseppe Falvo D'Urso LabateCharlotte DebbautLuc Van HoorebekeThomas De SchryverPatrick SegersGerardo Catapano

Modeling the drug transport during intraperitoneal chemotherapy

Margo SteuperaertGiuseppe Falve D'Urso LabateCharlotte DebbautWim CeelenPatrick Segers

Multilevel Imaging and Modelling of the Blood Circulation through the Normal and Cirrhotic Liver

Charlotte Debbaut

Optimization of construct perfusion in radial-flow packed-bed bioreactors for tissue engineering with a 2D stationary fluid dynamic model

Danilo DonatoGiuseppe Falvo D'Urso LabateCharlotte DebbautPatrick SegersGerardo Catapano

A1 Journal Article in BIOCHEMICAL ENGINEERING JOURNAL

Simulation of mass transport during intraperitoneal chemotherapy : a parametrical model of single tumor nodules

Margo SteuperaertGiuseppe Falvo D'Urso LabateCharlotte DebbautWim CeelenPatrick Segers

Time evolution of oxygen concentration profiles as cells grow and differentiate in RPBBS for bone TE from a 3D transient transport model

Giuseppe Falvo D'Urso LabateFrancesco TorchiaCharlotte DebbautPatrick SegersGerardo Catapano

2015

A multilevel modeling framework to study hepatic perfusion characteristics in case of liver cirrhosis

Geert PeetersCharlotte DebbautPieter CornillieThomas De SchryverDiethard MonbaliuWim LalemanPatrick Segers

A1 Journal Article in JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Automated 3D reconstruction of the normal and cirrhotic rat hepatic microcirculation using confocal microscopy: a feasibility study

Geert PeetersCharlotte DebbautJan DetrezWinnok De VosDiethard MonbaliuWim LalemanPatrick Segers

Design criterion for radial flux uniformity in radial-flow packed bed bioreactors for bone TE based on a 2D flow model

Danilo DonatoGiuseppe Falvo D'Urso LabateCharlotte DebbautPatrick SegersGerardo Catapano

Modeling the drug transport in a single tumor nodule during intraperitoneal chemotherapy

Margo SteuperaertCharlotte DebbautWim CeelenPatrick Segers

Modelling and quantifying the fluid transport through polylactic acid scaffolds

Margo SteuperaertCharlotte DebbautPeter DubruelSandra Van VlierbergheJasper Van HoorickWim CeelenPatrick Segers

Modelling the human liver microcirculation using 3D computational fluid dynamics and a porous medium approach

Charlotte DebbautDiethard MonbaliuPatrick Segers

Multi-level modelling of hepatic perfusion using vascular corrosion casting and µCT imaging

Geert PeetersCharlotte DebbautPieter CornillieThomas De SchryverDiethard MonbaliuWim LalemanPatrick Segers

Quantifying and modelling the fluid transport through polylactic acid scaffolds

Margo SteuperaertCharlotte DebbautPeter DubruelSandra Van VlierbergheJasper Van HoorickWim CeelenPatrick Segers

Study of the effect of permeability of annular porous scaffolds seeded with osteogenic cells on radial flux uniformity in radial flow packed-bed bioreactors for bone TE with a stationary 2D flow model

Danilo DonatoGiuseppe Falvo D'Urso LabateCharlotte DebbautPatrick SegersGerardo Catapano

Theoretical framework to enhance external solute transport to cells in radial flow packed-bed bioreactors for bone tissue engineering based on a stationary 2D transport model

Danilo DonatoGiuseppe Falvo D'Urso LabateCharlotte DebbautPatrick SegersGerardo Catapano

2014

A 3D porous media liver lobule model: the importance of vascular septa and anisotropic permeability for homogeneous perfusion

Charlotte DebbautJan VierendeelsJennifer H SiggersRodolfo RepettoDiethard MonbaliuPatrick Segers

A1 Journal Article in COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING

A multi-level computational model to characterize the hepatic circulation in human cirrhosis

Geert PeetersCharlotte DebbautPieter CornillieElin PauwelsDiethard MonbaliuWim LalemanPatrick Segers

A multi-level numerical model to assess the hepatic circulation in case of human cirrhosis

Geert PeetersCharlotte DebbautPieter CornillieThomas De SchryverDiethard MonbaliuWim LalemanPatrick Segers

A multiscale model to assess the perfusion in human cirrhosis

Geert PeetersCharlotte DebbautPieter CornillieWim LalemanPatrick Segers

An electrical analog model for liver perfusion: validation and calibration

Charlotte DebbautDiethard MonbaliuPascal VerdonckPatrick Segers

Analyzing the human liver vascular architecture by combining vascular corrosion casting and micro-CT scanning: a feasibility study

Charlotte DebbautPatrick SegersPieter CornillieChristophe CasteleynManuel DierickWim LalemanDiethard Monbaliu

A1 Journal Article in JOURNAL OF ANATOMY

Computational model of the mass transport in a tumor nodule during intraperitoneal chemotherapy

Margo SteuperaertCharlotte DebbautWim CeelenPatrick Segers

Electrical analog models to simulate the impact of partial hepatectomy on hepatic hemodynamics

Charlotte DebbautDavid De WildeChristophe CasteleynPieter CornillieManuel DierickLuc Van HoorebekeDiethard MonbaliuYe-Dong FanPatrick Segers

Engineering point of view on liver transplantation strategies: multi-level modeling of hepatic perfusion

Charlotte DebbautDiethard MonbaliuPatrick Segers

A1 Journal Article in TRANSPLANTATION PROCEEDINGS

Model-based optimization of radial flow in radial-flow packed-bed bioreactors for bone tissue engineering

Danilo DonatoIlaria Ester De NapoliCharlotte DebbautGiuseppe Falvo D'Urso LabatePatrick SegersGerardo Catapano

Modeling the mass transport in a tumor nodule during intraperitoneal chemotherapy

Margo SteuperaertCharlotte DebbautWim CeelenPatrick Segers

Multi-level modelling of hepatic perfusion in support of liver transplantation strategies

Charlotte Debbaut

Multi-level modelling of the hepatic perfusion

Charlotte DebbautDiethard MonbaliuPieter CornillieChristophe CasteleynManuel DierickJan VierendeelsPatrick Segers

Numerical simulations to characterize the hepatic microcirculation in human cirrhosis

Geert PeetersCharlotte DebbautPieter CornillieManuel DierickDiethard MonbaliuPatrick Segers

Transport model of radial-flow packed-bed bioreactors simulating natural bone vascular and interstitial fluid nutrients delivery

Danilo DonatoIlaria Ester De NapoliCharlotte DebbautPatrick SegersGerardo Catapano

Transport modeling of radial flow bioreactors packed with hollow cylindrical porous construct for bone tissue engineering: effect of external resistances to transport on solutes distribution

Danilo DonatoIlaria Ester De NapoliCharlotte DebbautPatrick SegersGerardo Catapano

Validation and calibration of an electrical analog model of human liver perfusion based on hypothermic machine perfusion experiments

Charlotte DebbautDiethard MonbaliuPatrick Segers

A1 Journal Article in INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

2013

Hydraulic input impedances as a tool to capture liver graft perfusion properties

Charlotte DebbautDiethard MonbaliuPatrick Segers

Measuring liver graft properties during machine perfusion using hepatic input impedances

Charlotte DebbautLaurent MeessemanDiethard MonbaliuPatrick Segers

Multi-level modelling of hepatic perfusion in support of liver transplantation strategies

Charlotte DebbautPatrick SegersDiethard Monbaliu

Multiscale modelling of the human hepatic perfusion

Charlotte DebbautDiethard MonbaliuPieter CornillieChristophe CasteleynManuel DierickPatrick Segers

Numerical simulations to characterize the hepatic microcirculation in human cirrhosis

Geert PeetersCharlotte DebbautPieter CornillieManuel DierickDiethard MonbaliuPatrick Segers

Semi-automatic analysis of the branching topology and geometrical characteristics of hepatic vascular trees

Charlotte DebbautJohn SledDiethard MonbaliuPatrick Segers

Vascular corrosion casting in research on liver diseases and transplantation : an overview of studies

Christophe CasteleynChristophe Van SteenkisteFemke HeindryckxStephanie CoulonNoémie Van HulCharlotte DebbautPieter CornillieDiethard MonbaliuSven FrancqueBart Tambuyzer et al.

2012

3D image-based modeling of the hepatic perfusion in liver transplantation research

Charlotte DebbautDiethard MonbaliuJan VierendeelsDavid De WildePatrick Segers

Flow competition between hepatic arterial and portal venous flow during hypothermic machine perfusion preservation of porcine livers

Diethard MonbaliuCharlotte DebbautWim HillewaertWim LalemanMAURICIO SAINZ-BARRIGAJacques PirennePatrick Segers

A1 Journal Article in INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

Hepatic input impedances as a measure of liver graft perfusion properties

Charlotte DebbautDiethard MonbaliuPatrick Segers

Liver transplantation: how can computer models help to shorten the waiting list?

Charlotte Debbaut

Modeling the human hepatic terminal microcirculation using 3D computational fluid dynamics

Charlotte DebbautJan VierendeelsDenis Van LooChristophe CasteleynPieter CornillieLuc Van HoorebekeDiethard MonbaliuPatrick Segers

Modeling the impact of partial hepatectomy on the hepatic hemodynamics using a rat model

Charlotte DebbautDavid De WildeChristophe CasteleynPieter CornillieDenis Van LooLuc Van HoorebekeDiethard MonbaliuYe-Dong FanPatrick Segers

A1 Journal Article in IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Modelling of the hepatic circulation by combining vascular corrosion casting and micro-CT imaging

Charlotte DebbautChristophe CasteleynPieter CornillieDenis Van LooJan VierendeelsPatrick SegersMonbaliu Diethard

Perfusion characteristics of the human hepatic microcirculation based on three-dimensional reconstructions and computational fluid dynamic analysis

Charlotte DebbautJan VierendeelsChristophe CasteleynPieter CornillieDenis Van LooPaul SimoensLuc Van HoorebekeDiethard MonbaliuPatrick Segers

A1 Journal Article in JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Portal hypertension after combined liver and intestinal transplantation, a diagnostic and therapeutic challenge?

Diethard MonbaliuJo VandersmissenGert De HertoghGert Van AsscheIlse HoffmanNoël KnopsCharlotte DebbautSam HeyeJacques PirenneGeert Maleux

A1 Journal Article in PEDIATRIC TRANSPLANTATION

Preserving the morphology and evaluating the quality of liver grafts by hypothermic machine perfusion: a proof-of-concept study using discarded human livers

Diethard MonbaliuQiang LuiLouis LibbrechtRita De VosKatrien VekemansCharlotte DebbautOlivier DetryTania RoskamsJos Van PeltJacques Pirenne

A1 Journal Article in LIVER TRANSPLANTATION

Semi-automatic morphological analysis of vascular trees: application to the human liver

Charlotte DebbautJohn G SledDiethard MonbaliuPatrick Segers

2011

Anatomy-based modelling of the human hepatic perfusion: covering the macro- to microcirculation scale

Charlotte DebbautDiethard MonbaliuChristophe CasteleynPieter CornillieDenis Van LooPatrick Segers

From vascular corrosion cast to electrical analog model for the study of human liver hemodynamics and perfusion

Charlotte DebbautDiethard MonbaliuChristophe CasteleynPieter CornillieDenis Van LooBert MasschaeleJacques PirennePaul SimoensLuc Van HoorebekePatrick Segers

A1 Journal Article in IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Multiscale modeling of the blood circulation in the human liver using vascular corrosion casting and micro-CT imaging techniques

Charlotte Debbautdiethard monbaliuChristophe CasteleynPieter CornillieDenis Van LooLuc Van HoorebekePaul SimoensJacques PirennePatrick Segers

Multiscale modeling of the human liver blood circulation : from the hepatic macrovasculature towards the microvasculature

Charlotte DebbautDiethard MonbaliuChristophe CasteleynPieter CornillieDenis Van LooJacques PirennePaul SimoensLuc Van HoorebekePatrick Segers

2010

3D micro-CT imaging of vascular corrosion casts to create 3D digital models for flow simulation in organ macro- and microcirculation : application to the human liver

Charlotte DebbautDiethard MonbaliuChristophe CasteleynPieter CornillieDenis Van LooPatrick Segers

3D models for flow simulations of organ macro- and microcirculation : application to the human liver

Charlotte DebbautDiethard MonbaliuChristophe CasteleynPieter CornillieDenis Van LooPatrick Segers

3D reconstruction and modeling of the blood flow through the human liver

Charlotte Debbaut

Crosstalk between anatomy and medical imaging: applications of micro-CT scanning in veterinary anatomy

Christophe CasteleynPieter CornillieMarjan DoomDenis Van LooChristophe Van SteenkisteBram TrachetCharlotte DebbautWim Van Den BroeckPaul Simoens

From human liver vascular corrosion cast to electrical analog model of the hepatic blood flow

Charlotte DebbautDiethard MonbaliuChristophe CasteleynPieter CornillieDenis Van LooBert MasschaeleJacques PirennePaul SimoensLuc Van HoorebekePatrick Segers

Levertransplantatie: de race naar betere bewaring van donorlevers

Charlotte Debbaut

Measurement of liver input impedances for validation of a human hepatic circulation model

Charlotte DebbautDiethard MonbaliuJacques PirennePatrick Segers

Micro-CT three-dimensional imaging of porcine and human hepatic vascular corrosion casts: development of hemodynamic models for organ transplantation research

Charlotte DebbautPieter CornillieDenis Van LooDiethard MonbaliuChristophe CasteleynBert MasschaeleJacques PirenneLuc Van HoorebekePatrick SegersPaul Simoens

2009

3D reconstruction and modelling of the blood circulation in the natural human liver

Charlotte Debbaut

Anatomical and electrical modelling of blood flow through the human liver

Charlotte DebbautDiethard MonbaliuChristophe CasteleynDenis Van LooBert MasschaelePieter CornillieJacques PirenneLuc Van HoorebekePaul SimoensPatrick Segers

Constructing a model of the blood flow in the human liver using contrast-loaded corrosion casting and micro-CT imaging

Charlotte DebbautDiethard MonbaliuChristophe CasteleynDenis Van LooBert MasschaelePieter CornillieJacques PirenneLuc Van HoorebekePaul SimoensPatrick Segers