Research Explorer

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Researcher

Céline Van Dender

Publications & Research Data

Awards & Distinctions

10 Results

2026

Balancing metabolism and regeneration in liver diseases through HNF4α targeting

Céline Van DenderJolien VandewalleClaude Libert

A1 Journal Article in TRENDS IN ENDOCRINOLOGY AND METABOLISM

Polymicrobial sepsis-induced changes in hepatic stellate cell communication in male C57BL/6J mice

Steven TimmermansCéline Van DenderMaxime RoesElise MoensTineke VanderhaeghenJolien VandewalleClaude Libert

A1 Journal Article in CELLS

2025

A crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS

Louise NuyttensMarah HeyerickMaxime RoesElise MoensCéline Van DenderCharlotte WallaeysTino HochepiedSteven TimmermansJolien VandewalleClaude Libert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Hepatic HNF4a and CAR in sepsis : investigating the mechanisms of their loss-of-function and impact on liver metabolism

Céline Van DenderClaude LibertKarolien De Bosscher

HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis

Céline Van DenderSteven TimmermansMaxime RoesMadeleine HellemansElise MoensLouise NuyttensMaarten ClaesBart RomanKarolien De BosscherJolien Vandewalle et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Unraveling mitochondrial pyruvate dysfunction to mitigate hyperlactatemia and lethality in sepsis

Louise NuyttensMarah HeyerickGeike HeremansElise MoensMaxime RoesCéline Van DenderLiesbet De BusJohan DecruyenaereJan De WaeleJolien Vandewalle et al.

A1 Journal Article in CELL REPORTS

2024

A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death

Céline Van DenderSteven TimmermansVille PaakinahoTineke VanderhaeghenJolien VandewalleMaarten ClaesBruno GarciaBart RomanJan De WaeleSiska Croubels et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

2023

The pig as a translational animal model to explore a new concept in the treatment of sepsis, today's largest unmet medical need

Fëllanza HalimiCharlotte CuypersBruna AlonsoEline HermansDiethard ReckelbusJolien VandewalleB. GarciaA. HerpainTineke VanderhaeghenCéline Van Dender et al.

The pig as a translational animal to explore a new concept in the treatment of sepsis, today's largest unmet medical need

Fëllanza HalimiCharlotte CuypersBruna AlonsoEline HermansDiethard ReckelbusJolien VandewalleBruno GarciaAntoine HerpainTineke VanderhaeghenCéline Van Dender et al.

2022

Hepatic peroxisome proliferator-activated receptor alpha dysfunction in porcine septic shock

Jolien VandewalleBruno GarciaSteven TimmermansTineke VanderhaeghenLise Van WyngeneMelanie EggermontHester DufoorCéline Van DenderFëllanza HalimiSiska Croubels et al.

A1 Journal Article in CELLS