Research Explorer

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Researcher

Cédric Bosteels

Awards & Distinctions

29 Results

2023

A Complement Atlas identifies interleukin 6 dependent alternative pathway dysregulation as a key druggable feature of COVID-19

Karel Van DammeLevi HosteJozefien DeclercqElisabeth De LeeuwBastiaan MaesLiesbet MartensRoos ColmanRobin BrowaeysCédric BosteelsStijn Verwaerde et al.

A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19

Karel Van DammeLevi HosteJozefien DeclercqElisabeth De LeeuwBastiaan MaesLiesbet MartensRoos ColmanRobin BrowaeysCédric BosteelsStijn Verwaerde et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

LXR signaling controls homeostatic dendritic cell maturation

Victor BosteelsSandra MaréchalClint De NolfSofie RennenJonathan MaelfaitSimon TavernierJessica VettersEvelien Van De VeldeFarzaneh FayazpourKim Deswarte et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

Daniela MatuozzoEstelle TalouarnAstrid MarchalPeng ZhangJeremy ManryYoann SeeleuthnerYu ZhangAlexandre BolzeMatthieu ChaldebasBaptiste Milisavljevic et al.

A1 Journal Article in GENOME MEDICINE

2022

Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19 : an open-label randomized controlled trial

Elisabeth De LeeuwKarel Van DammeJozefien DeclercqCédric BosteelsBastiaan MaesSimon TavernierLaurent DetalleTrevor SmartSophie GlattNincy Debeuf et al.

A1 Journal Article in RESPIRATORY RESEARCH

Isolation of conventional murine lung dendritic cell subsets

Elisabeth De LeeuwCédric BosteelsBart LambrechtHamida Hammad

Bookchapter in Asthma : methods and protocols

Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment

Cédric BosteelsKarel Van DammeElisabeth De LeeuwJozefien DeclercqBastiaan MaesVictor BosteelsLevi HosteLeslie NaesensNincy DebeufJulie Deckers et al.

A1 Journal Article in CELL REPORTS MEDICINE

Prospective longitudinal evaluation of hospitalised COVID-19 survivors 3 and 12 months after discharge

Natalie LorentYannick Vande WeygaerdeEveline ClaeysIpek Guler Caamano FajardoNicolas De VosWalter De WeverBihiyga SalhiIwein GyselinckCédric BosteelsBart Lambrecht et al.

A1 Journal Article in ERJ OPEN RESEARCH

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Levi HosteLisa RoelsLeslie NaesensVictor BosteelsStijn VanheeSam DupontCédric BosteelsRobin BrowaeysNiels VandammeKevin Verstaen et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2021

Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19 : a meta-analysis

[missing] The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working GroupIsabel MurGracia María MateoMaria del Mar GutierrezVirginia PomarNatividad de BenitoNoemí CorbachoSilvia HerreraLucia MillanJessica Muñoz et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul BastardAdrian GervaisTom Le VoyerJérémie RosainQuentin PhilippotJérémy ManryEleftherios MichailidisHans-Heinrich HoffmannShohei EtoMarina Garcia-Prat et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

CCR2-and Flt3-dependent inflammatory conventional type 2 dendritic cells are necessary for the induction of adaptive immunity by the human vaccine adjuvant system AS01

Cédric BosteelsKaat FierensSofie De PrijckJustine Van MoorleghemManon VanheerswynghelsCaroline De WolfAurelie ChalonCatherine CollignonHamida HammadArnaud M. Didierlaurent et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Coronavirus disease 2019 in patients with inborn errors of immunity : an international study

Isabelle MeytsGiorgia BucciolIsabella QuintiBénédicte NevenAlain FischerElena SeoaneEduardo Lopez-GranadosCarla GianelliAngel Robles-MarhuendaPierre-Yves Jeandel et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID) : a factorial, randomised, controlled trial

Jozefien DeclercqKarel Van DammeElisabeth De LeeuwBastiaan MaesCédric BosteelsSimon TavernierStefanie De BuyserRoos ColmanMaya HitesGil Verschelden et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

Local immune response to food antigens drives meal-induced abdominal pain

Javier Aguilera-LizarragaMorgane V. FlorensMaria Francesca ViolaPiyush JainLisse DecraeckerIris AppeltansMaria Cuende-EstevezNaomi FabreKim Van BeekEluisa Perna et al.

A1 Journal Article in NATURE

The role of DC subsets in respiratory viral infections and vaccination : a case of mistaken identity

Cédric BosteelsBart LambrechtHamida Hammad

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

Takaki AsanoBertrand BoissonFanny OnodiDaniela MatuozzoMarcela Moncada-VelezMajistor Raj Luxman Maglorius RenkilarajPeng ZhangLaurent MeertensAlexandre BolzeMarie Materna et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

2020

Case report : convalescent plasma, a targeted therapy for patients with CVID and severe COVID-19

Karel Van DammeSimon TavernierNele Van RoyElisabeth De LeeuwJozefien DeclercqCédric BosteelsBastiaan MaesMarieke De BruyneDelfien BogaertVictor Bosteels et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian ZhangPaul BastardZhiyong LiuJérémie Le PenMarcela Moncada-VelezJie ChenMasato OgishiIra K. D. SabliStephanie HodeibCecilia Korol et al.

A1 Journal Article in SCIENCE

Inflammatory type 2 cDCs acquire features of cDC1s and macrophages to orchestrate immunity to respiratory virus infection

Cédric BosteelsKatrijn NeytManon VanheerswynghelsMary van HeldenDorine SichienNincy DebeufSofie De PrijckVictor BosteelsNiels VandammeLiesbet Martens et al.

A1 Journal Article in IMMUNITY

Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC) : a structured summary of a study protocol for a randomised controlled trial

Cédric BosteelsBastiaan MaesKarel Van DammeElisabeth De LeeuwJozefien DeclercqANJA DELPORTEBENEDICTE DEMEYEREStefanie VermeerschMarnik VuylstekeJoren Willaert et al.

A1 Journal Article in TRIALS

Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC) : a structured summary of a study protocol for a randomised controlled trial (vol 21, 491, 2020)

Cédric BosteelsBastiaan MaesKarel Van DammeElisabeth De LeeuwJozefien DeclercqAnja DelporteBenedicte DemeyereStefanie VermeerschMarnik VuylstekeJoren Willaert et al.

Transcriptional regulation of DC fate specification

Cédric BosteelsCharlotte Scott

A1 Journal Article in MOLECULAR IMMUNOLOGY

Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID) : a structured summary of a study protocol for a randomised controlled trial

Bastiaan MaesCédric BosteelsElisabeth De LeeuwJozefien DeclercqKarel Van DammeANJA DELPORTEBENEDICTE DEMEYEREStefanie VermeerschMarnik VuylstekeJoren Willaert et al.

A1 Journal Article in TRIALS

Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID) : a structured summary of a study protocol for a randomised controlled trial (vol 21, 468, 2020)

Bastiaan MaesCédric BosteelsElisabeth De LeeuwJozefien DeclercqKarel Van DammeAnja DelporteBenedicte DemeyereStefanie VermeerschMarnik VuylstekeJoren Willaert et al.

Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV) : a structured summary of a study protocol for a randomised controlled trial

Jozefien DeclercqCédric BosteelsKarel Van DammeElisabeth De LeeuwBastiaan MaesAns VandecauterStefanie VermeerschAnja DelporteBénédicte DemeyereMarnik Vuylsteke et al.

A1 Journal Article in TRIALS

2019

Twelve-year follow-up study after endoscopic sinus surgery in patients with chronic rhinosinusitis with nasal polyposis

Lien CalusNicholas Van BruaeneCédric BosteelsSarah DejonckheereThibaut Van ZeleGabriële HoltappelsClaus BachertPhilippe Gevaert

A1 Journal Article in CLINICAL AND TRANSLATIONAL ALLERGY

2018

Isolation of conventional murine lung dendritic cell subsets

Cédric BosteelsBart LambrechtHamida Hammad

A2 Journal Article in CURRENT PROTOCOLS IN IMMUNOLOGY

2017

Epitope mapping and kinetics of CD4 T cell immunity to pneumonia virus of mice in the C57BL/6 strain

Lana VandersarrenCédric BosteelsManon VanheerswynghelsJames J MoonAndrew J EastonGert Van IsterdaelSophie JanssensBart LambrechtMary van Helden

A1 Journal Article in SCIENTIFIC REPORTS