Research Explorer

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Researcher

Caroline Merckx

Awards & Distinctions

15 Results

2025

Changes to the autophagy-related muscle proteome following short-term treatment with ectoine in the Duchenne muscular dystrophy mouse model mdx

Eulàlia Gómez ArmengolCaroline MerckxHanne De SutterJan De BleeckerBoel De Paepe

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2024

Ectoine treatment stimulates protein markers of autophagy efficiency in the Duchenne muscular dystrophy mouse model mdx

Eulàlia Gómez ArmengolCaroline MerckxJan De BleeckerBoel De Paepe

2023

Organic osmolytes and Duchenne muscular dystrophy : from homeostasis, inflammation and skeletal muscle regeneration to therapeutic target

Sandrine HerbeletCaroline MerckxBoel De Paepe

Bookchapter in Novel Research Aspects in Medicine and Medical Science Vol. 7

Osmolytes and their therapeutic applicability in the mdx mouse

Caroline MerckxJan De BleeckerBoel De Paepe

2022

Description of osmolyte pathways in maturing MDX mice reveals altered taurine and sodium/myo-inositol co-transporter levels

Caroline MerckxGwenny CosemansJana ZschuentzschJens SchmidtBoel De PaepeJan De Bleecker

Description of osmolyte pathways in maturing mdx mice reveals altered levels of taurine and sodium/myo-inositol co-transporters

Caroline MerckxGwenny CosemansJana ZschüntzschRobrecht RaedtJens SchmidtBoel De PaepeJan De Bleecker

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exploring the therapeutic potential of ectoine in Duchenne Muscular Dystrophy : comparison with taurine, a supplement with known beneficial effects in the mdx mouse

Caroline MerckxJana ZschüntzschStefanie MeyerRobrecht RaedtHanne VerschuereJens SchmidtBoel De PaepeJan De Bleecker

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inducible heat shock protein 70 levels in patients and the mdx mouse affirm regulation during skeletal muscle regeneration in muscular dystrophy

Gwenny CosemansCaroline MerckxJan De BleeckerBoel De Paepe

A2 Journal Article in FRONTIERS IN BIOSCIENCE (SCHOLAR ED.)

Osmotic stress-associated sodium/myo-inositol co-transporter is upregulated in skeletal muscle of the mdx mouse

Caroline MerckxGwenny CosemansJana ZschuentzschJens SchmidtJan De BleeckerBoel De Paepe

The role of taurine in skeletal muscle functioning and its potential as a supportive treatment for Duchenne Muscular Dystrophy

Caroline MerckxBoel De Paepe

A1 Journal Article in METABOLITES

2021

The PKA-p38MAPK-NFAT5-organic osmolytes pathway in Duchenne muscular dystrophy : from essential player in osmotic homeostasis, inflammation and skeletal muscle regeneration to therapeutic target

Sandrine HerbeletCaroline MerckxBoel De Paepe

A1 Journal Article in BIOMEDICINES

2020

Myo-inositol transporter SLC5A3 associates with degenerative changes and inflammation in sporadic inclusion body myositis

Boel De PaepeCaroline MerckxJana JarosovaMiryam CannizzaroJan De Bleecker

A1 Journal Article in BIOMOLECULES

2019

Effect of chemogenetic modulation of hippocampal neurons on depression and spatial memory impairment in a rat model for temporal lobe epilepsy

Erine CraeyMarie-Gabrielle GoossensJana DesloovereCaroline MerckxChris Van Den HauteVeerle BaekelandtDimitri De BundelIlse SmoldersKristl VonckPaul Boon et al.

Effect of chemogenetic modulation of hippocampal neurons on depression and spatial memory impairment in a rat model for temporal lobe epilepsy

Erine CraeyMarie-Gabrielle GoossensJana DesloovereCaroline MerckxChris Van Den HauteVeerle BaekelandtDimitri De BundelIlse SmoldersKristl VonckPaul Boon et al.

Long-term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy.

Jana DeslooverePaul BoonLars Emil LarsenCaroline MerckxMarie-Gabrielle GoossensC Van den HauteV BaekelandtD De BundelEvelien CarretteJean Delbeke et al.

A1 Journal Article in EPILEPSIA