Research Explorer

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Researcher

Cai Lin

Awards & Distinctions

10 Results

2024

N6-methyltubercidin gives sterile cure in a cutaneous Leishmania amazonensis mouse model

Cassandra PresentRoberson Donola GirãoCai LinGuy CaljonSerge Van CalenberghOtacilio MoreiraLeonardo Alexandre de Souza RuivoMarcos Meuser BatistaRaquel AzevedoDenise da Gama Jaen Batista et al.

A1 Journal Article in PARASITOLOGY

2022

Enrichment of a purine nucleoside analog library towards activity against Leishmania and Trypanosoma cruzi species

Cai LinSerge Van CalenberghMartijn Risseeuw

Exploration of 6-methyl-7-(hetero)aryl-7-deazapurine ribonucleosides as antileishmanial agents

Cai LinIzet KaralicAn MatheeussenPim-Bart FeijensFabian HulpiaLouis MaesGuy CaljonSerge Van Calenbergh

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

N6-modification of 7-deazapurine nucleoside analogues as anti-Trypanosoma cruzi and anti-Leishmania agents : structure-activity relationship exploration and in vivo evaluation

Cai LinDenise da Gama Jaén BatistaAna Lia MazzetiRoberson Donola GirãoGabriel Melo de OliveiraIzet KaralicFabian HulpiaMaria de Nazaré C. SoeiroLouis MaesGuy Caljon et al.

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Nucleoside analogues for the treatment of animal trypanosomiasis

Dorien MabilleKayhan IlbeigiSarah HendrickxMarzuq A. UngogoFabian HulpiaCai LinLouis MaesHarry P. de KoningSerge Van CalenberghGuy Caljon

A1 Journal Article in INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

2021

6-Methyl-7-deazapurine nucleoside analogues as broad-spectrum antikinetoplastid agents

Cai LinFabian HulpiaIzet KaralicLaurens De SchepperLouis MaesGuy CaljonSerge Van Calenbergh

A1 Journal Article in INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

6‐methyl‐7‐aryl‐7‐deazapurine nucleosides as anti‐trypanosoma cruzi agents : structure‐activity relationship and in vivo efficacy

Cai LinLudmila Ferreira de Almeida FiuzaCamila Cardoso SantosDaniela Ferreira NunesOtacílio Cruz MoreiraJakob BoutonIzet KaralicLouis MaesGuy CaljonFabian Hulpia et al.

A1 Journal Article in CHEMMEDCHEM

2020

Deazapurine nucleoside analogues as potent anti-Trypanosoma cruzi agents

Fabian HulpiaCai LinChristiane França da SilvaDenise da Gama Jean BatistaCamilla Cardoso-SantosLouis MaesGuy CaljonMaria de Nazaré C. SoeiroSerge Van Calenbergh

2019

Discovery of pyrrolo[2,3-b]pyridine (1,7-dideazapurine) nucleoside analogues as anti-Trypanosoma cruzi agents

Cai LinFabian HulpiaCristiane França da SilvaDenise da Gama Jaén BatistaKristof Van HeckeLouis MaesGuy CaljonMaria de Nazaré Correia SoeiroSerge Van Calenbergh

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Discovery of pyrrolo[2,3-b]pyridine nucleoside analogues as anti-Trypanosoma cruzi agents

Cai LinFabian HulpiaKristof Van HeckeLouis MaesGuy CaljonMaria de Nazaré C. SoeiroSerge Van Calenbergh