Research Explorer

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Researcher

Bruno Verhasselt

Awards & Distinctions

155 Results

2024

A cGAS-mediated type I interferon response in human CD4+T cells depends on productive infection and is conserved over HIV types and strains

Marija JanevskaTimothy CammaertEvelien NaessensBruno Verhasselt

A1 Journal Article in JOURNAL OF VIROLOGY

Antibiofilm activity of Prevotella species from the cystic fibrosis lung microbiota against Pseudomonas aeruginosa

Lucia GrassiKyle L. AsfahlSara Van den BosscheIne MaenhoutAndrea SassYannick Vande WeygaerdeEva Van BraeckelBruno VerhasseltJerina BoelensMichael M. Tunney et al.

A2 Journal Article in BIOFILM

Expansion of MALDI-TOF MS database as a strategy for identification of Haemophilus species other than H. influenzae

Eva WillemsHannelore HamerlinckAnne-Sophie MessiaenPetra SchelstraeteEva Van BraeckelYannick Vande WeygaerdeBruno VerhasseltJerina BoelensStien Vandendriessche

A1 Journal Article in ACTA CLINICA BELGICA

Nationwide quality assurance of high-throughput diagnostic molecular testing during the SARS-CoV-2 pandemic : role of the Belgian National Reference Centre

Reile JanssenLize CuypersLies LaenenEls KeyaertsKurt BeuselinckSunita JanssenswillenBram SlechtenJannes BodeElke WollantsKristel Van Laethem et al.

A1 Journal Article in VIROLOGY JOURNAL

Rapid detection of S. pyogenes and S. pneumoniae in pleural fluid for diagnosis of parapneumonic empyema

Kelly De SchuyterJerina BoelensAnne-Sophie MessiaenPetra SchelstraeteBruno VerhasseltDIANA HUIS IN 'T VELDSteven CallensErica SermijnYannick Vande WeygaerdeStien Vandendriesche

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Safety and efficacy of faecal microbiota transplantation in patients with mild to moderate Parkinson's disease (GUT-PARFECT) : a double-blind, placebo-controlled, randomised, phase 2 trial

Arnout BruggemanCharysse VandendriesscheHannelore HamerlinckDanny De LoozeDavid J. TateMarnik VuylstekeLindsey De CommerLindsay DevolderJeroen RaesBruno Verhasselt et al.

A1 Journal Article in ECLINICALMEDICINE

2023

EUCAST rapid antimicrobial susceptibility testing (RAST) compared to conventional susceptibility testing : implementation and potential added value in a tertiary hospital in Belgium

Gregory StrubbeAnne-Sophie MessiaenStien VandendriesscheBruno VerhasseltJerina Boelens

A1 Journal Article in ACTA CLINICA BELGICA

Pooling isolates to address the diversity in antimicrobial susceptibility of Pseudomonas aeruginosa in cystic fibrosis

Sara Van den BosscheEmmanuel AbatihLucia GrassiEmma De BroePetra RigoleJerina BoelensJORIS VAN CAENEGEMBruno VerhasseltIris JanssensEva Van Braeckel et al.

A1 Journal Article in MICROBIOLOGY SPECTRUM

Sanitary installations and wastewater plumbing as reservoir for the long-term circulation and transmission of carbapenemase producing Citrobacter freundii clones in a hospital setting

Hannelore HamerlinckAnnelies AerssensJerina BoelensAndrea DehaeneMichael McMahonAnne-Sophie MessiaenStien VandendriesscheAnja VelgheIsabel Leroux-RoelsBruno Verhasselt

A1 Journal Article in ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL

2022

Different long-term avidity maturation for IgG anti-spike and anti-nucleocapsid SARS-CoV-2 in hospitalized COVID-19 patients

Laura HeiremanJerina BoelensLiselotte CoorevitsBruno VerhasseltStien VandendriesscheElizaveta Padalko

A1 Journal Article in ACTA CLINICA BELGICA

Effects of cascade reporting of susceptibility profiles for Enterobacterales on broad-spectrum antibiotics use and resistance

Laura HeiremanStien VandendriesscheLiselotte CoorevitsFranky BuyleJan De WaeleDirk VogelaersBruno VerhasseltJerina Boelens

A1 Journal Article in EUROPEAN JOURNAL OF HOSPITAL PHARMACY

Evaluation of humoral and cellular responses in SARS-CoV-2 mRNA vaccinated immunocompromised patients

Matthijs OyaertMarie-Angélique De ScheerderSophie Van HerrewegeGuy LaureysSofie Van AsscheMelissa CambronLeslie NaesensLevi HosteKarlien ClaesFilomeen Haerynck et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Functional analysis of human and feline coronavirus cross-reactive antibodies directed against the SARS-CoV-2 fusion peptide

Nathalie VanderheijdenAnnelies StevaertJiexiong XieXiaolei RenCyril BarbezangeSam NoppenIsabelle DesombereBruno VerhasseltPeter GeldhofNick Vereecke et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Impact of the introduction of EUCAST’s concept of “area of technical uncertainty”

Eveline Van HonackerStien VandendriesscheLiselotte CoorevitsBruno VerhasseltJerina Boelens

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Sensitivity and specificity of 14 SARS-CoV-2 serological assays and their diagnostic potential in RT-PCR negative COVID-19 infections

Eveline Van HonackerLiselotte CoorevitsJerina BoelensBruno VerhasseltEva Van BraeckelFré BautersLiesbet De BusPetra SchelstraeteJef WillemsStien Vandendriessche et al.

A1 Journal Article in ACTA CLINICA BELGICA

Solid medical hospital waste in times of corona : increased volume but no increased biohazard risk

Norbert FraeymanEva Van BraeckelBruno VerhasseltPascal De WaegemaekerSusanne MahnikMarc HoffmannPaul GemmelKristof EecklooEric Mortier

A2 Journal Article in DETRITUS

Two years of genomic surveillance in Belgium during the SARS-CoV-2 pandemic to attain country-wide coverage and monitor the introduction and spread of emerging variants

Lize CuypersSimon DellicourSamuel L. HongBarney I. PotterBruno VerhasseltNick VereeckeLaurens LambrechtsKeith DurkinVincent BoursSofieke Klamer et al.

A1 Journal Article in VIRUSES-BASEL

2021

A rare but devastating cause of twin loss in a near-term pregnancy highlighting the features of severe SARS-CoV-2 placentitis

Sasha LibbrechtJolien Van CleemputLinos VandekerckhoveSofie ColmanElizaveta PadalkoBruno VerhasseltKoen Van de VijverAmélie DendoovenIsabelle DehaeneJo Van Dorpe

Editorial material

Combined oropharyngeal/nasal swab is equivalent to nasopharyngeal sampling for SARS-CoV-2 diagnostic PCR

Tania DesmetPeter De PaepeJerina BoelensLiselotte CoorevitsElizaveta PadalkoStien VandendriesscheIsabel Leroux-RoelsAnnelies AerssensSteven CallensEva Van Braeckel et al.

A1 Journal Article in BMC MICROBIOLOGY

Diagnosing COVID-19 : towards a feasible COVID-19 rule-out protocol

Jozefien De ClercqThomas MalfaitSimon MalfaitJerina BoelensLiselotte CoorevitsElizaveta PadalkoStien VandendriesscheBruno VerhasseltLieve MorbéeFré Bauters et al.

A1 Journal Article in ACTA CLINICA BELGICA

Fecal microbiota transplantation reduces symptoms in some patients with irritable bowel syndrome with predominant abdominal bloating : short- and long-term results from a placebo-controlled randomized trial

Tom HolvoetMarie JoossensJorge F. Vazquez-CastellanosEvelien ChristiaensLander HeyerickJerina BoelensBruno VerhasseltHans Van VlierbergheMartine De VosJeroen Raes et al.

A1 Journal Article in GASTROENTEROLOGY

2020

Evaluation of QuantiFERON-TB Gold Plus on Liaison XL in a Low-Tuberculosis-Incidence setting

E. De MaertelaereStien VandendriesscheBruno VerhasseltL. CoorevitsE. AndreElizaveta PadalkoJerina Boelens

A1 Journal Article in JOURNAL OF CLINICAL MICROBIOLOGY

How to handle phenotypic diversity of pseudomonas aeruginosa for antibiotic susceptibility testing in cystic fibrosis patients?

Stéphanie Van Den BosscheEmma De BroeEmmanuel AbatihJoris Van CaenegemBruno VerhasseltGINA VAN DAMMEEva Van BraeckelAnthony CrabbeTom Coenye

Prevalence of cytoplasmic actin mutations in diffuse large B-cell lymphoma and multiple myeloma : a functional assessment based on actin three-dimensional structures

Laura WitjesMarleen Van TroysBruno VerhasseltChristophe Ampe

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tackling diagnostic challenges during the first wave of COVID-19

Jozefien De ClercqThomas MalfaitSimon MalfaitLiselotte CoorevitsElizaveta PadalkoStien VandendriesscheBruno VerhasseltLieve MorbéeFré BautersKatrien Hertegonne et al.

Toilet drain water as a potential source of hospital room-to-room transmission of carbapenemase-producing Klebsiella pneumoniae

Laura HeiremanHannelore HamerlinckStien VandendriesscheJerina BoelensLiselotte CoorevitsEls De BrabanderePascal De WaegemaekerSaskia VerhofstedeK. ClausM. A. Chlebowicz-Flissikowska et al.

A1 Journal Article in JOURNAL OF HOSPITAL INFECTION

Vertebrate actin evolution and the assessment of mutations in cytoplasmic actins in DLBCL and multiple myeloma

Laura WitjesChristophe AmpeBruno Verhasselt

2019

A recurrent and transesophageal echocardiography-associated outbreak of extended-spectrum β-lactamase-producing Enterobacter cloacae complex in cardiac surgery patients

Tom Van MaerkenEls De BrabandereAudrey NoëlLiselotte CoorevitsPascal De WaegemaekerRaina AblorhStefaan BouchezINGRID HERCKHarlinde PeperstraetePierre Bogaerts et al.

A1 Journal Article in ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL

Evaluation of the Seegene Allplex™ Respiratory Panel for diagnosis of acute respiratory tract infections

Stien VandendriesscheElizaveta PadalkoElke WollantsCharlotte VerfaillieBruno VerhasseltLiselotte Coorevits

A1 Journal Article in ACTA CLINICA BELGICA

Methicillin-resistant staphylococcus aureus pneumonia in older people : a diagnostic and therapeutic challenge

Maja KiselinovaAnja VelgheRuth PiersBruno VerhasseltNele Van Den Noortgate

A1 Journal Article in ACTA CLINICA BELGICA

Silencing gene expression in dendritic cells as a platform for identification of novel HIV-related factors

Wojciech WitkowskiBruno Verhasselt

2018

Coumarin reduces virulence and biofilm formation in Pseudomonas aeruginosa by affecting quorum sensing, type III secretion and C-di-GMP levels

Yunhui ZhangAndrea SassHeleen Van AckerJasper WilleBruno VerhasseltFilip Van NieuwerburghVolkhard KaeverAurélie CrabbéTom Coenye

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Fecal microbiota transplantation in irritable bowel syndrome with predominant abdominal bloating : results from a double blind, placebo-controlled clinical trial

Tom HolvoetMarie JoossensJerina BoelensEvelien ChristiaensLander HeyerickBruno VerhasseltMartine De VosPieter HindryckxJeroen RaesDanny De Looze

Impact of AST meetings on antimicrobial therapy decisions in the ICU

Sofie DhaeseLiesbet De BusJerina BoelensLiselotte CoorevitsBruno VerhasseltPieter DepuydtJan De Waele

Improving timelines in reporting results from positive blood cultures : simulation of impact of rapid identification on therapy on a real-life cohort

Lien CattoirLiselotte CoorevitsIsabel Leroux-RoelsGeert ClaeysBruno VerhasseltJerina Boelens

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

The light chain IgLV3-21 defines a new poor prognostic subgroup in chronic lymphocytic leukemia : results of a multicenter study

Basile StamatopoulosThomas SmithEmerence CrompotKarlien PietersRuth CliffordMarek MrazPauline RobbeAdam BurnsAdele TimbsDavid Bruce et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

2017

Assessment of faecal microbial transfer in irritable bowel syndrome with severe bloating

Tom HolvoetMarie JoossensJun WangJerina BoelensBruno VerhasseltDebby LaukensHans Van VlierberghePieter HindryckxMartine De VosDanny De Looze et al.

A1 Journal Article in GUT

Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis

Sophie Van WeldenMartine De VosBen WielockxSimon TavernierMelissa DullaersSara NeytBenedicte DescampsLindsey DevisscherSarah DevrieseLien Van den Bossche et al.

A1 Journal Article in JOURNAL OF PATHOLOGY

Surveillance of endoscopes : comparison of different sampling techniques

Lien CattoirThomas VanzieleghemLISA FLORINTania HelleputteMartine De VosBruno VerhasseltJerina BoelensIsabel Leroux-Roels

A1 Journal Article in INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

2016

Entry of equid herpesvirus 1 into CD172a+ monocytic cells

Kathlyn LavalHerman FavoreelJolien Van CleemputKatrien PoelaertIvy BrownBruno VerhasseltHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

HIV triggers a cGAS-dependent, Vpu- and Vpr-regulated type I interferon response in CD4+ T cells

Jolien VermeireFerdinand RoeschDaniel SauterRéjane RuaDominik HotterAnouk Van NuffelHanne VanderstraetenEvelien NaessensVeronica IannucciAlessia Landi et al.

A1 Journal Article in CELL REPORTS

HIV-1 Vpr N-terminal tagging affects alternative splicing of the viral genome

Ann BaeyensEvelien NaessensAnouk Van NuffelKarin WeeningAnne-Marie ReillyEva ClaeysWim TrypsteenLinos VandekerckhoveSven EyckermanKris Gevaert et al.

A1 Journal Article in SCIENTIFIC REPORTS

Lipoprotein lipase in chronic lymphocytic leukemia : function and prognostic implications

Ans RomboutBruno VerhasseltJan Philippé

A1 Journal Article in EUROPEAN JOURNAL OF HAEMATOLOGY

Mimicking the tumour microenvironment of chronic lymphocytic leukaemia in vitro critically depends on the type of B-cell receptor stimulation

Ans RomboutSofie LustFritz OffnerEvelien NaessensBruno VerhasseltJan Philippé

A1 Journal Article in BRITISH JOURNAL OF CANCER

Pseudorabies virus glycoprotein gE triggers ERK1/2 phosphorylation and degradation of the pro-apoptotic protein Bim in epithelial cells

Maria Setas Lopes PontesCliff Van WaesbergheHans NauwynckBruno VerhasseltHerman Favoreel

A1 Journal Article in VIRUS RESEARCH

The human immunodeficiency virus (HIV) Rev-binding protein (HRB) is a co-factor for HIV-1 Nef-mediated CD4 downregulation

Alessia LandiCristina García TimermansEvelien NaessensHanne VanderstraetenVeronique StoveBruno Verhasselt

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection

Kristin HöhneRamona BusingerAnouk Van NuffelSebastian BolduanHerwig KoppensteinerAnn BaeyensJolien VermeireEva MalatinkováBruno VerhasseltMichael Schindler

A1 Journal Article in OPEN BIOLOGY

2015

Accurate quantification of episomal HIV-1 two-long terminal repeat circles by use of optimized DNA isolation and droplet digital PCR

Eva MalatinkováMaja KiselinovaPawel BonczkowskiWim TrypsteenPeter MessiaenJolien VermeireBruno VerhasseltKAREN VERVISCHLinos VandekerckhoveWard De Spiegelaere

A1 Journal Article in JOURNAL OF CLINICAL MICROBIOLOGY

Evaluation of type I interferon responses to HIV infection in CD4+ T cells

Jolien VermeireBruno Verhasselt

Functional exploration of ZAP70 and LPL in chronic lymphocytic leukemia

Ans RomboutJan PhilippéBruno Verhasselt

Identification of host factors and pathways involved in HIV-1-induced CD4 down-regulation

Alessia LandiBruno Verhasselt

Lipoprotein lipase SNPs rs13702 and rs301 correlate with clinical outcome in chronic lymphocytic leukemia patients

Ans RomboutBasile StamatopoulosLaurence LagneauxSofie LustFritz OffnerEvelien NaessensHanne VanderstraetenBruno VerhasseltJan Philippé

A1 Journal Article in PLOS ONE

Mimicking the tumor microenvironment of chronic lymphocytic leukemia in vitro critically depends on the type of B cell receptor stimulation

Ans RomboutSofie LustFritz OffnerEvelien NaessensBruno VerhasseltJan Philippé

SAMHD1's protein expression profile in humans

Sarah SchmidtKristina SchenkovaTarek AdamElina EriksonJudith Lehmann-KochSerkan SertelBruno VerhasseltOliver T FacklerFelix LasitschkaOliver T Keppler

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

Joni Van der MeulenViraj SanghviKonstantinos MavrakisKaat DurinckFang FangFilip MatthijssensPieter RondouMonica RosenTim PietersPeter Vandenberghe et al.

A1 Journal Article in BLOOD

Vpx-independent lentiviral transduction and shRNA-mediated protein knock-down in monocyte-derived dendritic cells

Wojciech WitkowskiJolien VermeireAlessia LandiEvelien NaessensHanne VanderstraetenHans NauwynckHerman FavoreelBruno Verhasselt

A1 Journal Article in PLOS ONE

2014

Accurate episomal HIV 2-LTR circles quantification using optimized DNA isolation and droplet digital PCR

Eva MalatinkováMaja KiselinovaPawel BonczkowskiWim TrypsteenPeter MessiaenJolien VermeireBruno VerhasseltKaren VervischLinos VandekerckhoveWard De Spiegelaere

Age-associated differential microRNA levels in human follicular fluid reveal pathways potentially determining fertility and success of in vitro fertilization

Araceli Diez FraileTim LammensKelly TillemanWojciech WitkowskiBruno VerhasseltPetra De SutterYves BenoitMarc EspeelKatharina D'Herde

A1 Journal Article in HUMAN FERTILITY

Genome-wide shRNA screening identifies host factors involved in early endocytic events for HIV-1-induced CD4 down-regulation

Alessia LandiJolien VermeireVeronica IannucciHanne VanderstraetenEvelien NaessensMostafa BentahirBruno Verhasselt

A1 Journal Article in RETROVIROLOGY

Replication competent virus as an important source of bias in HIV latency models utilizing single round viral constructs

Pawel BonczkowskiWard De SpiegelaereAlberto BosqueCory H WhiteAnouk Van NuffelEva MalatinkováMaja KiselinovaWim TrypsteenWojciech WitkowskiJolien Vermeire et al.

A1 Journal Article in RETROVIROLOGY

2013

CLL cells respond to B-cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progression

Valerie PedeAns RomboutJolien VermeireEvelien NaessensPieter MestdaghNore RobberechtHanne VanderstraetenNadine Van RoyJo VandesompeleFranki Speleman et al.

A1 Journal Article in PLOS ONE

Contributions of HIV-1 Nef to immune dysregulation in HIV-infected patients: a therapeutic target?

Wojciech WitkowskiBruno Verhasselt

A1 Journal Article in EXPERT OPINION ON THERAPEUTIC TARGETS

Efficient, Vpx independent shRNA transduction of monocyte derived dendritic cells as a tool for studying HIV transmission to primary T-cells

Wojciech WitkowskiVeronica IannucciEvelien NaessensHanne VanderstraetenBruno Verhasselt

Elevated soluble triggering receptor expressed on myeloid cells (sTREM)-1 levels in maternal serum during term and preterm labor

Inge TencyHans VerstraelenBart SaerensBruno VerhasseltMario VaneechoutteOlivier DegommeRita VerhelstMarleen Temmerman

A1 Journal Article in PLOS ONE

Expression of ZAP70 in chronic lymphocytic leukaemia activates NF-κB signalling

Valerie PedeAns RomboutJolien VermeireEvelien NaessensHanne VanderstraetenJan PhilippéBruno Verhasselt

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

HIV-1 infection induces a type I IFN response in primary CD4(+) T cells

Jolien VermeireVeronica IannucciEvelien NaessensKathleen Van LandeghemHanne VanderstraetenJo Van DammeBruno Verhasselt

New host factors and pathways involved in CD4 downregulation in HIV-1 infected cells

Alessia LandiJolien VermeireVeronica IannucciHanne VanderstraetenEvelien NaessensMostafa BentahirBruno Verhasselt

Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms

Anouk Van NuffelKevin AriënVeronique StoveMichael SchindlerEduardo O'NeillJan SchmökelInge Van de WalleEvelien NaessensHanne VanderstraetenKathleen Van Landeghem et al.

A1 Journal Article in RETROVIROLOGY

Vpr content of HIV-1 virions determines infection of resting peripheral blood CD4⁺ lymphocytes

Anouk Van NuffelFrancis ImpensAnn BaeyensStijn VanheeWojciech WitkowskiElien VandermarliereHanne VanderstraetenEvelien NaessensKathleen Van LandeghemSophie Vermaut et al.

2012

A catalogue of putative HIV-1 protease host cell substrates

Francis ImpensEvy TimmermanAn StaesKathleen MoensKevin AriënBruno VerhasseltJoël VandekerckhoveKris Gevaert

A1 Journal Article in BIOLOGICAL CHEMISTRY

Characterization of LEDGF/p75 genetic variants and association with HIV-1 disease progression

Peter MessiaenWard De SpiegelaereJose AlcamiKaren VervischPetra Van AckerBruno VerhasseltPieter MeuwissenEsther CalongeNuria GonzalezFelix Gutierrez-Rodero et al.

A1 Journal Article in PLOS ONE

Comprehensive characterization of LEDGF/p75 in a HIV-1 infected patient cohort

Peter MessiaenWard De SpiegelaereJose AlcamiPaul CouckePetra Van AckerKaren VervischBruno VerhasseltPieter MeeuwissenBruce PoppeDirk Vogelaers et al.

Function and prognostic relevance of ZAP-70 and LPL in chronic lymphocytic leukemia

Valerie PedeBruno VerhasseltJan Philippé

Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function

Pieter MeuwissenBettina StolpVeronica IannucciJolien VermeireEvelien NaessensKalle SakselaMatthias GeyerGuido VanhamKevin AriënOliver T Fackler et al.

A1 Journal Article in RETROVIROLOGY

Imbalances between matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) in maternal serum during preterm labor

Inge TencyHans VerstraelenIvo KroesGabriële HoltappelsBruno VerhasseltMario VaneechoutteRita VerhelstMarleen Temmerman

A1 Journal Article in PLOS ONE

Quantification of reverse transcriptase activity by real-time PCR as a fast and accurate method for titration of HIV, lenti- and retroviral vectors

Jolien VermeireEvelien NaessensHanne VanderstraetenAlessia LandiVeronica IannucciAnouk Van NuffelTom TaghonMassimo PizzatoBruno Verhasselt

A1 Journal Article in PLOS ONE

sTREM-1 levels are elevated in maternal serum during term and preterm labour

Inge TencyHans VerstraelenOlivier DegommeRita VerhelstBart SaerensBruno VerhasseltMario VaneechoutteMarleen Temmerman

2011

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells

An De WeerJoni Van der MeulenPieter RondouTom TaghonTorsten A KonradKatleen De PreterPieter MestdaghTom Van MaerkenNadine Van RoyMarta Jeison et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Nef: a notorious enigmatic factor in HIV biology

Bruno Verhasselt

Editorial material

One protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef

Alessia LandiVeronica IannucciAnouk Van NuffelPieter MeuwissenBruno Verhasselt

A1 Journal Article in CURRENT HIV RESEARCH

Porcine sialoadhesin (CD169/Siglec-1) is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages

Peter DelputteHanne Van GorpHerman FavoreelInge HoebekeIris DelrueHannah DewerchinFrederik VerdonckBruno VerhasseltEric CoxHans Nauwynck

A1 Journal Article in PLOS ONE

The Nef-infectivity enigma : mechanisms of enhanced lentiviral infection

Jolien VermeireGriet VanbillemontWojciech WitkowskiBruno Verhasselt

A1 Journal Article in CURRENT HIV RESEARCH

2010

A real-time polymerase chain reaction assay for rapid, sensitive, and specific quantification of the JAK2V617F mutation using a locked nucleic acid-modified oligonucleotide

Barbara DenysHakim El HousniFriedel NolletBruno VerhasseltJan Philippé

A1 Journal Article in JOURNAL OF MOLECULAR DIAGNOSTICS

Microrna expression in pediatric precursor-B acute lymphoblastic leukemia: biology, classification and prognosis

Tim LammensBarbara De MoerlooseJonas Van BaelenJoni Van der MeulenPieter MestdaghBruno VerhasseltJan PhilippéFranki SpelemanYves Benoit

Rho GTPase Cdc42 is essential for human T-cell development

Kaatje SmitsVeronica IannucciVeronique StovePeter Van HauweEvelien NaessensPieter MeuwissenKevin AriënMostafa BentahirJean PlumBruno Verhasselt

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

2009

A RAPID, SENSITIVE AND SPECIFIC REAL-TIME POLYMERASE CHAIN REACTION ASSAY FOR QUANTIFICATION OF THE JAK2V617F ALLELE BURDEN

B. DenysH El HousniF NolletBruno VerhasseltJan Philippé

Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs

Pieter Van VlierbergheAn De WeerPieter MestdaghTom FeysKatleen De PreterAnne De PaepeKathleen LambeinJo VandesompeleNadine Van RoyBruno Verhasselt et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Downregulation of miR-449a is essential for the survival of EVI1 positive leukemic cells through modulation of NOTCH1 and BCL2

An De WeerPieter MestdaghKatleen De PreterJoni Van der MeulenPieter Van VlierbergheTom Van MaerkenNadine Van RoyMarta JeisonIsaac YanivBarbara Cauwelier et al.

EFFECT OF ZAP-70 ON MIRNA EXPRESSION PROFILE IN CHRONIC LYMPHOCYTIC LEUKEMIA

Valerie PedeJan PhilippéPieter MestdaghJo VandesompeleBruno Verhasselt

MODULATION OF MIR-449A EXPRESSION DECREASES CELL VIABILITY, INCREASES APOPTOSIS AND INDUCES DIFFERENTIATION IN EVI1 DEREGULATED LEUKEMIA CELLS

An De WeerBruce PoppePieter MestdaghKatleen De PreterPieter Van VlierbergheNadine Van RoyM JeisonB CauwelierBruno VerhasseltJan Philippé et al.

2008

Characterization of putative immune evasion mechanisms of feline infectious peritonitis virus

Hannah DewerchinHans NauwynckBruno VerhasseltHerman Favoreel

Clathrin- and caveolae-independent entry of feline infectious peritonitis virus in monocytes depends on dynamin

Evelien Van HammeHannah DewerchinEls CornelissenBruno VerhasseltHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22

An De WeerFranki SpelemanBarbara CauwelierNadine Van RoyNurten YigitBruno VerhasseltBarbara De MoerlooseYves BenoitLucien NoensDominik Selleslag et al.

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

EVII activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22)

An De WeerBruce PoppeBarbara CauwelierA CARLIERJ DIERICKBruno VerhasseltJan PhilippéNadine Van RoyFranki Speleman

A1 Journal Article in BMC CANCER

Efficient gene transfer in CLL by mRNA electroporation

Femke Van BockstaeleValerie PedeEvelien NaessensStefanie Van CoppernolleV VAN TENDELOOBruno VerhasseltJan Philippé

A1 Journal Article in LEUKEMIA

HIV Nef: Role in pathogenesis and viral fitness

Kevin AriënBruno Verhasselt

A1 Journal Article in CURRENT HIV RESEARCH

MICRORNA PROFILING OF EVI1 DEREGULATED MYELOID LEUKEMIA

An De WeerBruce PoppePieter MestdaghPieter Van VlierbergheNadine Van RoyAnne De PaepeBruno VerhasseltJo VandesompeleFranki Speleman

Minimal residual disease detection at day 35 in childhood acute lymphoblastic leukemia: Which technique(s) to use?

Katrien SwertsBarbara De MoerlooseB DENYSM BAKKUSBruno VerhasseltYves BenoitJan Philippé

Prognostic markers in chronic lymphocytic leukemia: A comprehensive review

Femke Van BockstaeleBruno VerhasseltJan Philippé

A1 Journal Article in Blood Reviews

Surface-expressed viral proteins in feline infectious peritonitis virus-infected monocytes are internalized through a clathrin- and caveolae-independent pathway

Hannah DewerchinEls CornelissenEvelien Van HammeKaatje SmitsBruno VerhasseltHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Which technique(s) to use when studying minimal residual disease at day 35 in childhood acute lymphoblastic leukemia: a multicenter approach.

Barbara De MoerlooseKatrien SwertsM BakkusA UyttebroeckN BoeckxP VandenbergheBruno VerhasseltA Van DammeC DemanetYves Benoit et al.

Which technique(s) to use when studying minimal residual disease at day 35 in childhood acute lymphoblastic leukemia: a multicenter approach.

Barbara De MoerlooseKatrien SwertsM BAKKUSA UYTTEBROECKN BOECKXP VANDENBERGHEBruno VerhasseltA VAN DAMMEC DEMANETJan Philippé et al.

2007

A detailed inventory of DNA copy number alterations in four commonly used Hodgkin lymphoma cell lines

Tom FeysBruce PoppeKatleen De PreterNadine Van RoyBruno VerhasseltPascale De PaepeAnne De PaepeFranki Speleman

A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines

Tom FeysBruce PoppeKatleen De PreterNadine Van RoyBruno VerhasseltPascale De PaepeAnne De PaepeFranki Speleman

A1 Journal Article in HAEMATOLOGICA

Array CGH analysis of subnanogram quantities of DNA using whole genome amplification: opportunities for detection of copy number alterations in Hodgkin's lymphoma

Tom FeysBart PoppeBruno VerhasseltPascale De PaepeBjörn MentenJo VandesompeleNadine Van RoyAnne De PaepeFranki Speleman

Characterization of reemerging chikungunya virus

M SOURISSEAUC SCHILTEN CASARTELLIC TROUILLETF GUIVEL-BENHASSINED RUDNICKAN SOL-FOULONK LE ROUXMC PREVOSTH FSIHI et al.

A1 Journal Article in PLOS PATHOGENS

Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCR β-HOXA rearrangement : a study of the Groupe Francophone de Cytogénétique Hématologique

Barbara CauwelierH CavéC GervaisM LessardC BarinC PerotJ Van den AkkerF MugneretC CharrinMP Pagès et al.

A1 Journal Article in LEUKEMIA

Identification of EVI1 transcriptional target genes using RNAI

An De WeerBruce PoppeB CAUWEUERNadine Van RoyBruno VerhasseltFranki Speleman

Lipoprotein lipase mRNA expression in whole blood is a prognostic marker in B cell chronic lymphocytic leukemia

Femke Van BockstaeleValerie PedeA JANSSENSF CALLEWAERTFritz OffnerBruno VerhasseltJan Philippé

A1 Journal Article in CLINICAL CHEMISTRY

MicroRNA profiling of EVI1 deregulated myeloid leukemia

An De WeerBruce PoppePieter MestdaghNadine Van RoyAnne De PaepeBruno VerhasseltJo VandesompeleFranki Speleman

Prognostic significance of lipoprotein lipase expression in B-cell chronic lymphocytic leukemia

Femke Van BockstaeleValerie PedeAnn JanssensFilip CallewaertFritz OffnerBruno VerhasseltJan Philippé

Tumor necrosis factor promotes T-cell at the expense of B-cell lymphoid development from cultured human CD34(+) cord blood cells

K SMITSMagda De SmedtEvelien NaessensGreet De SmetVeronique StoveTom TaghonJean PlumBruno Verhasselt

A1 Journal Article in EXPERIMENTAL HEMATOLOGY

2006

EBV negative Richter's syndrome from a coexistent clone after salvage treatment with alemtuzumab in a CLL patient

A JANSSENSM BERTHP DE PAEPEBruno VerhasseltNadine Van RoyLucien NoensJan PhilippéFritz Offner

A1 Journal Article in AMERICAN JOURNAL OF HEMATOLOGY

Generation of embryonic stem cell lines from mouse blastocysts developed in vivo and in vitro: relation to Oct-4 expression

S TIELENSBruno VerhasseltJ LIUMarc DhontJosiane Van der ElstMaria Cornelissen

A1 Journal Article in REPRODUCTION

Human transferrin G277S mutation and iron deficiency in pregnancy.

Joris DelangheHans VerstraelenIlse PynaertL DEBELSYouri TaesBruno VerhasseltStefaan De HenauwMarleen Temmerman

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Kolmogorov-Smirnov statistical test for analysis of ZAP-70 expression in B-CLL, compared with quantitative PCR and IgVH mutation status

Femke Van BockstaeleAnn JanssensAnne PietteFilip CallewaertValerie PedeFritz OffnerBruno VerhasseltJan Philippé

A1 Journal Article in CYTOMETRY PART B-CLINICAL CYTOMETRY

Modelling thymic HIV-1 Nef effects

Veronique StoveBruno Verhasselt

A1 Journal Article in CURRENT HIV RESEARCH

Multiple gene knock-down by a single lentiviral vector expressing an array of short hairpin RNAs

Veronique StoveKaatje SmitsEvelien NaessensJean PlumBruno Verhasselt

A1 Journal Article in ELECTRONIC JOURNAL OF BIOTECHNOLOGY

The TCRB-HOXA rearrangement in T-ALL leads to a specific increase of the alternative HOXA10b transcript

B CauwelierH CAVÉN DASTUGUEP HEIMANNH ANTOINE-POIRELBruno VerhasseltYves BenoitBarbara De MoerlooseNadine Van RoyA HAGEMEIJER et al.

Vitamin D binding protein, bone status and body composition in community-dwelling elderly men.

Youri TaesStefan GoemaereGM HUANGI VAN POTTELBERGHDirk De BacquerBruno VerhasseltCeline Van den BroekeJoris DelangheJean Kaufman

A1 Journal Article in BONE

2005

A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias

Franki SpelemanBarbara CauwelierN DASTUGUEJ COOLSBruno VerhasseltBruce PoppeNadine Van RoyJo VandesompeleC GRAUXA UYTTEBROECK et al.

A1 Journal Article in LEUKEMIA

Correlation of ZAP-70 analysed by RT-PCR with ZAP-70 determined by flow cytometry and with IgVH mutational status in B-CLL

Jan PhilippéFemke Van BockstaeleFilip CallewaertA JANSSENSFritz OffnerBruno Verhasselt

Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8 alpha beta

Veronique StoveInge Van de WalleEvelien NaessensElisabeth CoeneChristophe StoveJean PlumBruno Verhasselt

A1 Journal Article in JOURNAL OF VIROLOGY

Nasal polyps in patients with and without cystic fibrosis: a differentiation by innate markers and inflammatory mediators

Sofie ClaeysHelen Van HoeckeGabriële HoltappelsPhilippe GevaertTine De BelderBruno VerhasseltPaul Van CauwenbergeClaus Bachert

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Novel cryptic chromosomal rearrangements in childhood acute lymphoblastic leukemia detected by multiple color fluorescent in situ hybridization

Bruce PoppeBarbara CauwelierH VAN LIMBERGENNurten YigitJan PhilippéBruno VerhasseltAnne De PaepeYves BenoitFranki Speleman

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

VH-gene usage is of prognostic value in B-cell chronic lymphocytic leukemia

Femke Van BockstaeleKaatje SmitsFritz OffnerAnne JanssensJan PhilippéBruno Verhasselt

2004

Macrophage mannose receptor in chronic sinus disease

Sofie ClaeysT DE BELDERGabriële HoltappelsPhilippe GevaertBruno VerhasseltPaul Van CauwenbergeClaus Bachert

A1 Journal Article in ALLERGY

The restricted V-H-gene usage is of prognostic value in B-cell chronic lymphocytic leukemia

Jan PhilippéFemke Van BockstaeleKaatje SmitsFritz OffnerBruno VerhasseltANN JANSSENS

2003

ALK activation by the CLTC-ALK fusion is a recurrent event in large B-cell lymphoma

P DE PAEPEM BAENSH VAN KRIEKENBruno VerhasseltM STULANN SIMONSBruce PoppeGenevieve LaureysP BRONSPieter Vandenberghe et al.

A1 Journal Article in BLOOD

Generation of transgenic T cells from human CD34+ cord blood cells

Bruno VerhasseltEvelien NaessensVeronique Stove

Bookchapter in Cytokines and Colony Stimulating Factors.

Human beta-defensins and toll-like receptors in the upper airway

Sofie ClaeysT DE BELDERGabriële HoltappelsPhilippe GevaertBruno VerhasseltPaul Van CauwenbergeClaus Bachert

A1 Journal Article in ALLERGY

Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development

Veronique StoveEvelien NaessensChristophe StoveT SWIGUTJean PlumBruno Verhasselt

A1 Journal Article in BLOOD

The quantification of MDR1 transcripts by real-time RT-PCR does not predict drug resistance in childhood acute lymphoblastic leukemia

Katrien SwertsBarbara De MoerlooseB LEUSCatharina DhoogeGenevieve LaureysBruno VerhasseltYves BenoitJan Philippé

2002

Active form of notch imposes T cell fate in human progenitor cells

Magda De SmedtKatia ReynvoetTessa KerreTom TaghonBruno VerhasseltBart VandekerckhoveGeorges LeclercqJean Plum

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Enforced expression of HOX-A10 drives human hematopoietic precursor cells toward the monocytic lineage

Tom TaghonF StolzMagda De SmedtM CnockaertBruno VerhasseltJean PlumGeorges Leclercq

HOX-A10 regulates hematopoietic lineage commitment: evidence for a monocyte-specific transcription factor

Tom TaghonFrank StolzMagda De SmedtM CNOCKAERTBruno VerhasseltJean PlumGeorges Leclercq

A1 Journal Article in BLOOD

Identification of biologically active chemokine isoforms from ascitic fluid and elevated levels of CCL18/pulmonary and activation-regulated chemokine in ovarian carcinoma.

E SCHUTYSERS STRUYFP PROOSTG OPDENAKKERGenevieve LaureysBruno VerhasseltL PEPERSTRAETEI VAN DE PUTTEA SACCANIP ALLAVENA et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2000

Efficiency of transgenic T cell generation from gene-marked cultured human CD34(+) cord blood cells is determined by their maturity and the cytokines present in the culture medium.

Bruno VerhasseltE NAESSENSM DE SMEDTJean Plum

A1 Journal Article in GENE THERAPY

Human T lymphopoiesis - In vitro and in vivo study models.

Jean PlumM DE SMEDTBruno VerhasseltTessa KerreDominique VanheckeBart VandekerckhoveGeorges Leclercq

A1 Journal Article in NEUROIMMUNOMODULATION

Signals from the IL-9 receptor are critical for the early stages of human intrathymic T cell development.

M DE SMEDTBruno VerhasseltTessa KerreDominique VanheckeE NAESSENSGeorges LeclercqJC RENAULDJ VAN SNICKJean Plum

A1 Journal Article in JOURNAL OF IMMUNOLOGY

1999

Human immunodeficiency virus nef gene expression affects generation and function of human T cells, but not dendritic cells

Bruno VerhasseltEvelien NaessensChris VerhofstedeMagda De SmedtSigrid SchollenTessa KerreDominique VanheckeJean Plum

A1 Journal Article in BLOOD

In vitro intrathymic differentiation kinetics of human fetal liver CD34(+)CD38(-) progenitors reveals a phenotypically defined dendritic/T-NK precursor split

Jean PlumMagda De SmedtBruno VerhasseltFritz OffnerTessa KerreD VANHECKEGeorges LeclercqBart Vandekerckhove

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Thymic repopulation by CD34+ human cord blood cells after expansion in stroma-free culture

Bruno VerhasseltTessa KerreEvelien NaessensDominique VanheckeMagda De SmedtBart VandekerckhoveJean Plum

A1 Journal Article in BLOOD

1998

Retrovirally transduced CD34(++) human cord blood cells generate T cells expressing high levels of the retroviral encoded green fluorescent protein marker in vitro.

Bruno VerhasseltM DE SMEDTR VERHELSTE NAESSENSJean Plum

A1 Journal Article in BLOOD

1997

Human thymocytes become lineage committed at an early postselection CD69(+) stage, before the onset of functional maturation.

Dominique VanheckeBruno VerhasseltM DE SMEDTGeorges LeclercqJean PlumBart Vandekerckhove

A1 Journal Article in JOURNAL OF IMMUNOLOGY

MHC class II molecules are required for initiation of positive selection but not during terminal differentiation of human CD4 single positive thymocytes

Dominique VanheckeBruno VerhasseltM DESMEDTB DEPAEPEGeorges LeclercqJean PlumBart Vandekerckhove

A1 Journal Article in JOURNAL OF IMMUNOLOGY

1996

Interleukin-7 is a critical growth factor in early human T-cell development.

Jean PlumM DESMEDTGeorges LeclercqBruno VerhasseltBart Vandekerckhove

A1 Journal Article in BLOOD

1995

Case of recurrent Flavimonas oryzihabitans bacteremia associated with an implanted central venous catheter (Port-A-Cath) : assessment of clonality by arbitrarily primed PCR

Bruno VerhasseltGeert ClaeysA ElaichouniGerda VerschraegenGenevieve LaureysMario Vaneechoutte

A1 Journal Article in JOURNAL OF CLINICAL MICROBIOLOGY

Differentiation to T helper cells in the thymus : gradual acquisition of T helper cell function by CD3⁺CD4⁺ cells

Dominique VanheckeBruno VerhasseltVeronique DebackerGeorges LeclercqJean PlumBart Vandekerckhove

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Mogelijkheden en obstakels voor toepassing van DNA en RNA amplificatie en hybridisatietechnieken in de diagnostiek van infecties.

Mario VaneechoutteBruno VerhasseltChris VerhofstedeGeert ClaeysGerda VerschraegenJean Plum

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

1994

COLORIMETRIC QUANTIFICATION OF URINARY IRON DURING DEFEROXAMINE THERAPY.

Bruno VerhasseltJoris DelangheAlain VerstraeteGeert Leroux-Roels

A1 Journal Article in CLINICAL CHEMISTRY

1992

Interleukin-1 is a motility factor for human breast carcinoma cells in vitro : additive effect with interleukin-6

Bruno VerhasseltJozef Van DammeNicolas Van LarebekeW PutMarc BrackeC De PotterMarcus Mareel

A1 Journal Article in EUROPEAN JOURNAL OF CELL BIOLOGY

1991

Arrest of MCF-7 cell migration by laminin in vitro: possible mechanisms

P CoopmanBruno VerhasseltMarc BrackeGeorges De BruyneV CastronovoM SobelJM FoidartFrans Van RoyMarcus Mareel

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

1990

Effects of serotonin and ketanserin on the functional morphology of chick down feather bulbi in vitro

Hilde BeeleHubert ThierensBruno VerhasseltLeo De Ridder

A1 Journal Article in EXPERIENTIA

In vitro culture of chick down feather bulbi: a tool to obtain proliferating and differentiating keratinocytes in an organotypic structure

Hilde BeeleBruno VerhasseltHubert ThierensLeo De Ridder

A1 Journal Article in EXPERIENTIA