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Researcher
Bruce Poppe
Profile
Projects
Publications
Activities
Awards & Distinctions
200
Results
2023
A Solve-RD ClinVar-based reanalysis of 1522 index cases from ERN-ITHACA reveals common pitfalls and misinterpretations in exome sequencing
Anne-Sophie Denommé-Pichon
Leslie Matalonga
Elke de Boer
Adam Jackson
Elisa Benetti
Siddharth Banka
Ange-Line Bruel
Andrea Ciolfi
Jill Clayton-Smith
Bruno Dallapiccola
et al.
A1
Journal Article
in
GENETICS IN MEDICINE
2023
Exome sequencing and multigene panel testing in 1,411 patients with adult-onset neurologic disorders
Nika Schuermans
Hannah Verdin
Jody Ghijsels
Madeleine Hellemans
Elke Debackere
Elke Bogaert
Sofie Symoens
Leslie Naesens
Elien Lecomte
David Crosiers
et al.
A1
Journal Article
in
NEUROLOGY-GENETICS
2023
Loss of phospholipase PLAAT3 causes a mixed lipodystrophic and neurological syndrome due to impaired PPARγ signaling
Nika Schuermans
Salima El Chehadeh
Dimitri Hemelsoet
Jérémie Gautheron
Marie-Christine Vantyghem
Sonia Nouioua
Meriem Tazir
Corinne Vigouroux
Martine Auclair
Elke Bogaert
et al.
A1
Journal Article
in
NATURE GENETICS
2023
Twist exome capture allows for lower average sequence coverage in clinical exome sequencing
Burcu Yaldiz
Erdi Kucuk
Juliet Hampstead
Tom Hofste
Rolph Pfundt
Jordi Corominas Galbany
Tuula Rinne
Helger G. Yntema
Alexander Hoischen
Marcel Nelen
et al.
A1
Journal Article
in
HUMAN GENOMICS
2023
2022
Lipodystrophy due to genetic deficiency of picornavirus host factor and obesity regulator PLAAT3
Nika Schuermans
Salima El Chehadeh
Dimitri Hemelsoet
Elke Bogaert
Elke Debackere
Pascale Hilbert
Nike Van Doninck
Marie-Caroline Taquet
Toon Rosseel
Griet De Clercq
et al.
C3
Conference
2022
Shortcutting the diagnostic odyssey : the multidisciplinary program for undiagnosed rare diseases in adults (UD-PrOZA)
Nika Schuermans
Dimitri Hemelsoet
Wim Terryn
Sanne Steyaert
Rudy Van Coster
Paul Coucke
Wouter Steyaert
Bert Callewaert
Elke Bogaert
Patrick Verloo
et al.
A1
Journal Article
in
ORPHANET JOURNAL OF RARE DISEASES
2022
2021
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers
Juliette Coignard
Michael Lush
Jonathan Beesley
Tracy A. O'Mara
Joe Dennis
Jonathan P. Tyrer
Daniel R. Barnes
Lesley McGuffog
Goska Leslie
Manjeet K. Bolla
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2021
Prevalence of germline pathogenic variants in cancer predisposing genes in Czech and Belgian pancreatic cancer patients
Greet Wieme
Jan Kral
Toon Rosseel
Petra Zemankova
Bram Parton
Michal Vocka
Mattias Van Heetvelde
Petra Kleiblova
Bettina Blaumeiser
Jana Soukupova
et al.
C3
Conference
2021
Prevalence of germline pathogenic variants in cancer predisposing genes in Czech and Belgian pancreatic cancer patients
Greet Wieme
Jan Kral
Toon Rosseel
Petra Zemankova
Bram Parton
Michal Vocka
Mattias Van Heetvelde
Petra Kleiblova
Bettina Blaumeiser
Jana Soukupova
et al.
A1
Journal Article
in
CANCERS
2021
Prolonged recombinant pregnancy hormone use in BRCA1 and BRCA2 mutation carriers
Herman Depypere
Yanrong Su
Nhi Dang
Bruce Poppe
Frank Stanczyk
Jaak Janssens
Jose Russo
A1
Journal Article
in
EUROPEAN JOURNAL OF CANCER PREVENTION
2021
Tissue is the issue : when a second biopsy reveals the true diagnosis
Anne-Marie Bogaert
Anne Hoorens
Marleen Praet
Jo Van Dorpe
Bruce Poppe
Marie-Angélique De Scheerder
Editorial material
2021
2020
Cancer Surveillance Guideline for individuals with PTEN hamartoma tumour syndrome
Marc Tischkowitz
Chrystelle Colas
Sjaak Pouwels
Nicoline Hoogerbrugge
on behalf of European Reference Network GENTURI
on behalf of PHTS Guideline Dev Grp
Kathleen Claes
Bruce Poppe
Robin de Putter
A1
Journal Article
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2020
Guidelines for the Li-Fraumeni and heritable TP53-related cancer syndromes
Thierry Frebourg
Svetlana Bajalica Lagercrantz
Carla Oliveira
Rita Magenheim
D. Gareth Evans
on behalf of European Reference Network GENTURI
Kathleen Claes
Bruce Poppe
Robin de Putter
A1
Journal Article
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2020
2019
Analysis of patients with a personal and/or family history of pancreatic cancer with a custom designed broad cancer predisposition gene panel
Greet Wieme
Toon Rosseel
Bram Parton
Bettina Blaumeiser
Sabine Tejpar
Bruce Poppe
Kim De Leeneer
Kathleen Claes
C3
Conference
2019
Analysis of patients with a personal and/or family history of pancreatic cancer with a custom designed broad cancer predisposition gene panel
Greet Wieme
Toon Rosseel
Bram Parton
Bettina Blaumeiser
Jenneke van den Ende
Sabine Tejpar
Bruce Poppe
Kim De Leeneer
Kathleen Claes
C3
Conference
2019
Application of a custom designed broad cancer predisposition gene panel for the analysis of patients with a personal and/or family history of pancreatic cancer
Greet Wieme
Toon Rosseel
Bram Parton
Bettina Blaumeiser
Jenneke van den Ende
Sabine Tejpar
Bruce Poppe
Kim De Leeneer
Kathleen Claes
C3
Conference
2019
Boosting care and knowledge about hereditary cancer : European Reference Network on Genetic Tumour Risk Syndromes
Janet R Vos
Lisette Giepmans
Claas Röhl
Nicoline Geverink
Nicoline Hoogerbrugge
on behalf of ERN Genturis
Bruce Poppe
Kathleen Claes
A1
Journal Article
in
FAMILIAL CANCER
2019
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
Manuel A Ferreira
Eric R Gamazon
Fares Al-Ejeh
Kristiina Aittomaki
Irene L Andrulis
Hoda Anton-Culver
Adalgeir Arason
Volker Arndt
Kristan J Aronson
Banu K Arun
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2019
Non-invasive prenatal testing (NIPT) : how to handle secondary findings of maternal chromosomal abnormalities
Machteld Baetens
Tom Sante
Sarah Vergult
M. De Smet
S. Janssens
Olivier Vanakker
Bert Callewaert
Bruce Poppe
Annelies Dheedene
Björn Menten
C3
Conference
2019
2018
Accurate detection and quantification of epigenetic and genetic second hits in BRCA1 and BRCA2-associated hereditary breast and ovarian cancer reveals multiple co-acting second hits
Mattias Van Heetvelde
Mieke Van Bockstal
Bruce Poppe
Kathleen Lambein
Toon Rosseel
Lilit Atanesyan
Dieter Deforce
Ivo Van Den Berghe
Kim De Leeneer
Jo Van Dorpe
et al.
A1
Journal Article
in
CANCER LETTERS
2018
Future perspectives of genome-scale sequencing
Wouter Steyaert
Steven Callens
Paul Coucke
Bart Dermaut
Dimitri Hemelsoet
Wim Terryn
Bruce Poppe
A1
Journal Article
in
ACTA CLINICA BELGICA
2018
IRF2BPL is associated with neurological phenotypes
Paul C Marcogliese
Vandana Shashi
Rebecca C Spillmann
Nicholas Stong
Jill A Rosenfeld
Mary Kay Koenig
Julian A Martínez-Agosto
Matthew Herzog
Agnes H Chen
Patricia I Dickson
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF HUMAN GENETICS
2018
Identification of germline mutations in cancer predisposition genes in patients with a personal and/or family history of pancreatic cancer
Greet Wieme
Toon Rosseel
Bettina Blaumeiser
Jenneke van den Ende
Sabine Tejpar
Bruce Poppe
Kim De Leeneer
Kathleen Claes
C3
Conference
2018
Identification of germline mutations in cancer predisposition genes in patients with a personal and/or family history of pancreatic cancer
Greet Wieme
Bruce Poppe
Toon Rosseel
Kim De Leeneer
Kathleen Claes
C3
Conference
2018
Identification of germline mutations in cancer predisposition genes in patients with a personal and/or family history of pancreatic cancer
Greet Wieme
Toon Rosseel
Bettina Blaumeiser
Jenneke van den Ende
Sabine Tejpar
Bruce Poppe
Kim De Leeneer
Kathleen Claes
C3
Conference
2018
Identification of germline mutations in cancer predisposition genes in patients with a personal and/or family history of pancreatic cancer
Greet Wieme
Toon Rosseel
Bettina Blaumeiser
Jenneke van den Ende
Sabine Tejpar
Bruce Poppe
Kim De Leeneer
Kathleen Claes
C3
Conference
2018
Thorough in silico and in vitro cDNA analysis of 21 putative BRCA1 and BRCA2 splice variants and a complex tandem duplication in BRCA2 allowing the identification of activated cryptic splice donor sites in BRCA2 exon 11
Annelot Baert
Eva Machackova
Ilse Coene
Carol Cremin
Kristin Turner
Cheryl Portigal-Todd
Marie Jill Asrat
Jennifer Nuk
Allison Mindlin
Sean Young
et al.
A1
Journal Article
in
HUMAN MUTATION
2018
Tissue is the issue : when a second biopsy reveals the true diagnosis
Anne-Marie Bogaert
Anne Hoorens
Marleen Praet
Jo Van Dorpe
Bruce Poppe
Marie-Angélique De Scheerder
C3
Conference
2018
2017
Analysis of chromosomal radiosensitivity of healthy BRCA2 mutation carriers and non-carriers in BRCA families with the G2 micronucleus assay
Annelot Baert
Julie Depuydt
Tom Van Maerken
Bruce Poppe
Fransiska Malfait
Tim Van Damme
Sylvia De Nobele
Gianpaolo Perletti
Kim De Leeneer
Kathleen Claes
et al.
A1
Journal Article
in
ONCOLOGY REPORTS
2017
Evaluation of polygenic risk scores for breast and ovarian cancer risk prediction in BRCA1 and BRCA2 mutation carriers
Karoline B Kuchenbaecker
Lesley McGuffog
Daniel Barrowdale
Andrew Lee
Penny Soucy
Sue Healey
Joe Dennis
Michael Lush
Mark Robson
Amanda B Spurdle
et al.
A1
Journal Article
in
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
2017
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
Catherine M Phelan
Karoline B Kuchenbaecker
Jonathan P Tyrer
Siddhartha P Kar
Kate Lawrenson
Stacey J Winham
Joe Dennis
Ailith Pirie
Marjorie J Riggan
Ganna Chornokur
et al.
A1
Journal Article
in
NATURE GENETICS
2017
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
Roger L Milne
Karoline B Kuchenbaecker
Kyriaki Michailidou
Jonathan Beesley
Siddhartha Kar
Sara Lindström
Shirley Hui
Audrey Lemaçon
Penny Soucy
Joe Dennis
et al.
A1
Journal Article
in
NATURE GENETICS
2017
In-house developed 15-gene sequencing panel for acute myeloid leukemia and myelodysplasia allows robust detection of genetic defects including FLT3-ITD and CEBPA mutations
Joni Van der Meulen
Barbara Denys
Elien De Latter
Steve Lefever
Toon Rosseel
Wouter Steyaert
GRETA VAN DER CRUYSSEN
Isabelle Rottiers
David Creytens
Jo Van Dorpe
et al.
C3
Conference
2017
In-house developed 15-gene sequencing panel for acute myeloid leukemia and myelodysplasia allows robust detection of genetic defects including FLT3-ITD and CEBPA mutations
Joni Van der Meulen
Barbara Denys
Elien De Latter
Steve Lefever
Toon Rosseel
Wouter Steyaert
GRETA VAN DER CRUYSSEN
Isabelle Rottiers
David Creytens
Jo Van Dorpe
et al.
C3
Conference
2017
Novel molecular insights and targeted therapies in T-cell acute lymphoblastic leukemia
Sofie Peirs
Bruce Poppe
Pieter Van Vlierberghe
Dissertation
2017
Prediction of breast and prostate cancer risks in male BRCA1 and BRCA2 mutation carriers using polygenic risk scores
Julie Lecarpentier
Valentina Silvestri
Karoline B Kuchenbaecker
Daniel Barrowdale
Joe Dennis
Lesley McGuffog
Penny Soucy
Goska Leslie
Piera Rizzolo
Anna Sara Navazio
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2017
Second hit landscape in BRCA-associated breast cancer
Mattias Van Heetvelde
Mieke Van Bockstal
Trees Lepez
Steve Lefever
Leen Pieters
Kathleen Lambein
Marleen Praet
Ivo Van Den Berghe
Frauke Coppieters
Nadine Van Roy
et al.
C3
Conference
2017
Second hit landscape in BRCA1/2-associated breast cancer
Mattias Van Heetvelde
Mieke Van Bockstal
Trees Lepez
Kathleen Lambein
Dieter Deforce
Anne Vral
Bruce Poppe
Kim De Leeneer
Jo Van Dorpe
Kathleen Claes
C3
Conference
2017
Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia
Sofie Peirs
V Frismantas
Filip Matthijssens
W Van Loocke
Tim Pieters
Niels Vandamme
Béatrice Lintermans
MP Dobay
Geert Berx
Bruce Poppe
et al.
A1
Journal Article
in
LEUKEMIA
2017
2016
BRD4 inhibition improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Tim Pieters
Niels Vandamme
Geert Berx
Bruce Poppe
Pieter Van Vlierberghe
C3
Conference
2016
BRD4 inhibition improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Tim Pieters
Niels Vandamme
Geert Berx
Bruce Poppe
Pieter Van Vlierberghe
C3
Conference
2016
Evaluation of the role of germline RECQL variants in Belgian patients referred for genetic testing in the context of familial breast/ovarian cancer
Greet Wieme
Ilse Coene
Liselotte Vergote
Bruce Poppe
Fransiska Malfait
Tom Van Maerken
Kim De Leeneer
Kathleen Claes
C3
Conference
2016
Expanding the TLX1 regulome in T-cell acute lymphoblastic leukemia towards long noncoding RNAs
Kaat Durinck
Wouter Van Loocke
Inge Van de Walle
Joni Van der Meulen
Pieter-Jan Volders
Nadine Van Roy
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
et al.
C3
Conference
2016
Fine-scale mapping at 9p22.2 identifies candidate causal variants that modify ovarian cancer risk in BRCA1 and BRCA2 mutation carriers
E Vigorito
KB Kuchenbaecker
J Beesley
J Adlard
BA Agnarsson
IL Andrulis
BK Arun
L Barjhoux
M Belotti
J Benitez
et al.
A1
Journal Article
in
PLOS ONE
2016
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
FJ Couch
KB Kuchenbaecker
K Michailidou
GA Mendoza-Fandino
S Nord
J Lilyquist
C Olswold
E Hallberg
S Agata
H Ahsan
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2016
Increased chromosomal radiosensitivity in asymptomatic carriers of a heterozygous BRCA1 mutation
Annelot Baert
Julie Depuydt
Tom Van Maerken
Bruce Poppe
Fransiska Malfait
Katrien Storm
Jenneke van den Ende
Tim Van Damme
Sylvia De Nobele
Gianpaolo Perletti
et al.
A1
Journal Article
in
BREAST CANCER RESEARCH
2016
Long noncoding RNA signatures define oncogenic subtypes in T-cell acute lymphoblastic leukemia
Annelynn Wallaert
Kaat Durinck
Wouter Van Loocke
Inge Van de Walle
Filip Matthijssens
Pieter-Jan Volders
Francisco Avila Cobos
Dries Rombaut
Pieter Rondou
Pieter Mestdagh
et al.
A1
Journal Article
in
LEUKEMIA
2016
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2
Valentina Silvestri
Daniel Barrowdale
Anna Marie Mulligan
Susan L Neuhausen
Stephen Fox
Beth Y Karlan
Gillian Mitchell
Paul James
Darcy L Thull
Kristin K Zorn
et al.
A1
Journal Article
in
BREAST CANCER RESEARCH
2016
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer
Antoinette Hollestelle
Frederieke H van der Baan
Andrew Berchuck
Sharon E Johnatty
Katja K Aben
Bjarni A Agnarsson
Kristiina Aittomäki
Elisa Alducci
Irene L Andrulis
Hoda Anton-Culver
et al.
A1
Journal Article
in
GYNECOLOGIC ONCOLOGY
2016
Targeting BET family proteins improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Béatrice Lintermans
Tim Pieters
Niels Vandamme
Geert Berx
Bruce Poppe
Pieter Van Vlierberghe
C3
Conference
2016
Targeting BET family proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia
Sofie Peirs
Viktoras Frismantas
Filip Matthijssens
Béatrice Lintermans
Tim Pieters
Niels Vandamme
Wouter Van Loocke
Geert Berx
Bruce Poppe
Jean-Pierre Bourquin
et al.
C3
Conference
2016
The T-ALL oncogene TLX1 controls enhancer lncRNA expression
Karen Verboom
Kaat Durinck
Wouter Van Loocke
Filip Matthijssens
Inge Van de Walle
Annelynn Wallaert
Pieter-Jan Volders
Nadine Van Roy
Yves Benoit
Bruce Poppe
et al.
C3
Conference
2016
The combination of ABT-199 and JQ1 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Tim Pieters
Niels Vandamme
Béatrice Lintermans
Lindy Reunes
Geert Berx
Bruce Poppe
Pieter Van Vlierberghe
C3
Conference
2016
2015
Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer
Timothy R Rebbeck
Nandita Mitra
Fei Wan
Olga M Sinilnikova
Sue Healey
Lesley McGuffog
Sylvie Mazoyer
Georgia Chenevix-Trench
Douglas F Easton
Antonis C Antoniou
et al.
A1
Journal Article
in
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
2015
BRCA1, BRCA2 and PALB2 mutations and CHEK2 c. 1100delC in different South African ethnic groups diagnosed with premenopausal and/or triple negative breast cancer
FZ Francies
T Wainstein
Kim De Leeneer
A Cairns
M Murdoch
S Nietz
H Cubasch
Bruce Poppe
Tom Van Maerken
Brecht Crombez
et al.
A1
Journal Article
in
BMC CANCER
2015
Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia
Kaat Durinck
Wouter Van Loocke
Joni Van der Meulen
Inge Van de Walle
Maté Ongenaert
Pieter Rondou
Annelynn Wallaert
CE de Bock
Nadine Van Roy
Bruce Poppe
et al.
A1
Journal Article
in
LEUKEMIA
2015
Epigenetics in T-cell acute lymphoblastic leukemia
Sofie Peirs
Joni Van der Meulen
Inge Van de Walle
Tom Taghon
Franki Speleman
Bruce Poppe
Pieter Van Vlierberghe
A1
Journal Article
in
IMMUNOLOGICAL REVIEWS
2015
MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia
Evelien Mets
Joni Van der Meulen
Gert Van Peer
Michael Boice
Pieter Mestdagh
Inge Van de Walle
Tim Lammens
Steven Goossens
Barbara De Moerloose
Yves Benoit
et al.
A1
Journal Article
in
LEUKEMIA
2015
Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia
Farzaneh Ghazavi
Tim Lammens
Nadine Van Roy
Bruce Poppe
Franki Speleman
Yves Benoit
Pieter Van Vlierberghe
Barbara De Moerloose
A1
Journal Article
in
EXPERIMENTAL HEMATOLOGY
2015
Nevoid basal cell carcinoma syndrome and dysgerminoma : an incidental association?
Isabelle Hoorens
Maya Van de Kerckhove
Bruce Poppe
Katrien Vossaert
A1
Journal Article
in
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
2015
Novel biological insights in T-cell acute lymphoblastic leukemia
Kaat Durinck
Steven Goossens
Sofie Peirs
Annelynn Wallaert
Wouter Van Loocke
Filip Matthijssens
Tim Pieters
Gloria Milani
Tim Lammens
Pieter Rondou
et al.
A1
Journal Article
in
EXPERIMENTAL HEMATOLOGY
2015
Oncogenetic testing and follow-up for women with familial breast/ovarian cancer, Li-Fraumeni syndrome and Cowden syndrome
Jo Robays
Sabine Stordeur
Frank Hulstaert
Tom Van Maerken
Kathleen Claes
Nicolas Janin
Gert Matthijs
Daphné 't Kint de Roodenbeke
Martine Berlière
Hans Wildiers
et al.
Report
2015
Oncogenetic testing for persons with hereditary endocrine cancer syndromes
Joan Vlayen
Marie Bex
Bert Bravenboer
Kathleen Claes
Bruno Lapauw
Alexandre Persu
Kris Poppe
Urielle Ullman
Tom Van Maerken
Laurent Vroonen
et al.
Report
2015
Oncogenetic testing, diagnosis and follow-up in Birt-Hogg-Dubé syndrome, familial atypical multiple mole melanoma syndrome and neurofibromatosis 1 and 2
Jo Robays
Sabine Stordeur
Frank Hulstaert
Jean-François Baurain
Lieve Brochez
Teofila Caplanusi
Kathleen Claes
Eric Legius
Sylvie Rottey
Dirk Schrijvers
et al.
Report
2015
The G2 micronucleus-assay for the analysis of in vitro chromosomal radiosensitivity in individuals carrying a BRCA1 mutation
Annelot Baert
Julie Depuydt
Bruce Poppe
Tom Van Maerken
Fransiska Malfait
Tim Van Damme
Sylvia De Nobele
Kim De Leeneer
Kathleen Claes
Anne Vral
C3
Conference
2015
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia
Joni Van der Meulen
Viraj Sanghvi
Konstantinos Mavrakis
Kaat Durinck
Fang Fang
Filip Matthijssens
Pieter Rondou
Monica Rosen
Tim Pieters
Peter Vandenberghe
et al.
A1
Journal Article
in
BLOOD
2015
Transcriptional antagonism between the cooperative oncogenes TLX1 and NOTCH1 in T-cell acute lymphoblastic leukemia.
Kaat Durinck
Wouter Van Loocke
Joni Van der Meulen
Inge Van de Walle
Pieter Rondou
Charles E De Bock
Bruce Poppe
Jan Cools
Jean Soulier
Tom Taghon
et al.
C3
Conference
2015
2014
ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Steven Goossens
Inge Van de Walle
Katia Ruggero
Charles E de Bock
Sandrine Degryse
Kirsten Canté-Barrett
Delphine Briot
Emmanuelle Clappier
et al.
A1
Journal Article
in
BLOOD
2014
ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in early immature T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Steven Goossens
Kirsten Canté-Barrett
Tim Lammens
Barbara De Moerloose
Yves Benoit
Jean Soulier
Bruce Poppe
Tom Taghon
et al.
C3
Conference
2014
ABT-199 mediated inhibition of BCL2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Steven Goossens
Charles De Bock
Kirsten Canté-Barrett
Tim Lammens
Inge Van de Walle
Barbara De Moerloose
Yves Benoit
Bruce Poppe
et al.
C3
Conference
2014
Breast-cancer risk in families with mutations in PALB2
AC Antoniou
S Casadei
T Heikkinen
D Barrowdale
K Pylkäs
J Roberts
A Lee
D Subramanian
Kim De Leeneer
F Fostira
et al.
A1
Journal Article
in
NEW ENGLAND JOURNAL OF MEDICINE
2014
DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers
Ana Osorio
Roger L Milne
Karoline Kuchenbaecker
Tereza Vaclová
Guillermo Pita
Rosario Alonso
Paolo Peterlongo
Ignacio Blanco
Miguel de la Hoya
Mercedes Duran
et al.
A1
Journal Article
in
PLOS GENETICS
2014
Integrative analysis of the NOTCH1 regulatory network identifies key downstream lncRNAs in acute T-cell lymphoblastic leukemia and normal T-cell development
Annelynn Wallaert
Kaat Durinck
Pieter Rondou
Inge Van de Walle
Wouter Van Loocke
Pieter-Jan Volders
Maté Ongenaert
Nadine Van Roy
Bruce Poppe
Yves Benoit
et al.
C3
Conference
2014
LncRNA profiling in T-cell acute lymphoblastic leukemia predicts a functional connection between lncRNAs and the major T-ALL genetic subgroups
Annelynn Wallaert
Kaat Durinck
Wouter Van Loocke
Pieter-Jan Volders
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
Jean Soulier
Jan Cools
et al.
C3
Conference
2014
Mate pair sequencing for the detection of chromosomal aberrations in patients with intellectual disability and congenital malformations
Sarah Vergult
Ellen Van Binsbergen
Tom Sante
Silke Nowak
Olivier Vanakker
Kathleen Claes
Bruce Poppe
Nathalie Van der Aa
Markus J van Roosmalen
Karen Duran
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2014
MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia
Evelien Mets
Gert Van Peer
Joni Van der Meulen
Michael Boice
Tom Taghon
Steven Goossens
Pieter Mestdagh
Yves Benoit
Barbara De Moerloose
Nadine Van Roy
et al.
A1
Journal Article
in
HAEMATOLOGICA
2014
The G2 micronucleus assay for the analysis of in vitro chromosomal radiosensitivity in individuals carrying a BRCA1 or BRCA2 mutation
Annelot Baert
Julie Depuydt
Bruce Poppe
Tom Van Maerken
Fransiska Malfait
Tim Van Damme
Sylvia De Nobele
Kim De Leeneer
Kathleen Claes
Anne Vral
C3
Conference
2014
The G2-micronucleus assay for the detection of in vitro chromosomal radiosensitivity in BRCA1 and BRCA2 mutation carriers
Annelot Baert
Julie Depuydt
Bruce Poppe
Tom Van Maerken
Fransiska Malfait
Tim Van Damme
Kim De Leeneer
Kathleen Claes
Anne Vral
C3
Conference
2014
The NOTCH1 driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia
Annelynn Wallaert
Kaat Durinck
Pieter Rondou
Inge Van de Walle
Wouter Vanloocke
Pieter-Jan Volders
Suzanne Vanhauwaert
Ellen Geerdens
Maté Ongenaert
Nadine Van Roy
et al.
C3
Conference
2014
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia
Kaat Durinck
Annelynn Wallaert
Inge Van de Walle
Wouter Van Loocke
Pieter-Jan Volders
Suzanne Vanhauwaert
Ellen Geerdens
Yves Benoit
Nadine Van Roy
Bruce Poppe
et al.
A1
Journal Article
in
HAEMATOLOGICA
2014
The first lncRNA landscape of major genetic T-ALL subsets and guilt-by-association analysis for ETP-ALL specific lncRNAs
Annelynn Wallaert
Kaat Durinck
Wouter Van Loocke
Pieter-Jan Volders
Inge Van de Walle
Yves Benoit
Bruce Poppe
Jo Vandesompele
Tom Taghon
Jean Soulier
et al.
C3
Conference
2014
Uncovering the microRNA landscape in T-cell acute lymphoblastic leukemia
Evelien Mets
Franki Speleman
Bruce Poppe
Dissertation
2014
Unique lncRNA signatures mark the major T-ALL genetic subgroups
Annelynn Wallaert
Kaat Durinck
Wouter Van Loocke
Pieter-Jan Volders
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
Jean Soulier
Jan Cools
et al.
C3
Conference
2014
2013
Analysis of the novel Fanconi anemia gene SLX4/FANCP in familial breast cancer cases
Janine L Bakker
Saskia van Mil
Gerry Crossan
Nelly Sabbaghian
Kim De Leeneer
Bruce Poppe
Muriel Adank
Hans Gille
Henk Vergeul
Hanne Meijers-Heijboer
et al.
A1
Journal Article
in
HUMAN MUTATION
2013
Development of an S-G2 micronucleus assay for the detection of in vitro chromosomal radiosensitivity in high-risk women subjected to early mammography screening for breast cancer
Anne Vral
Julie Depuydt
Annelot Baert
Bruce Poppe
Tom Van Maerken
Fransiska Malfait
Kim De Leeneer
Marc D'Hooghe
Kathleen Claes
C3
Conference
2013
Expanding the TLX1 regulate in T-cell acute lymphoblastic leukemia towards long non-coding RNAs
Kaat Durinck
Joni Van der Meulen
Maté Ongenaert
Pieter-Jan Volders
Annelynn Wallaert
Nadine Van Roy
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
et al.
C3
Conference
2013
Expanding the TLX1-regulome in T cell acute lymphoblastic leukemia towards long non-coding RNAs
Kaat Durinck
Joni Van der Meulen
Maté Ongenaert
Pieter-Jan Volders
Annelynn Wallaert
Nadine Van Roy
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
et al.
C3
Conference
2013
Fabry nephropathy: indications for screening and guidance for diagnosis and treatment by the European Renal Best Practice
Wim Terryn
Pierre Cochat
Roseline Froissart
Alberto Ortiz
Yves Pirson
Bruce Poppe
Andreas Serra
Wim Van Biesen
Raymond Vanholder
Christoph Wanner
A1
Journal Article
in
NEPHROLOGY DIALYSIS TRANSPLANTATION
2013
Matepair sequencing for the detection of chromosomal aberrations in patients with intellectual disability and congenital malformations
Sarah Vergult
Ellen Van Binsbergen
Tom Sante
Silke Nowak
Olivier Vanakker
Kathleen Claes
Bruce Poppe
Nathalie Van der Aa
MJ Van Roosmalen
K Duran
et al.
C3
Conference
2013
MiR-128 is a novel PHF6 targeting regulatory non-coding RNA acting as a T-ALL oncogene
Evelien Mets
Joni Van der Meulen
Gert Van Peer
Michael Boice
Pieter Mestdagh
Tom Taghon
David Avran
Barbara De Moerloose
Yves Benoit
Bruce Poppe
et al.
C3
Conference
2013
Prevalence of Fabry disease in a predominantly hypertensive population with left ventricular hypertrophy
Wim Terryn
Gert Deschoenmakere
Jan De Keyser
Wouter Meersseman
Wim Van Biesen
Brigitte Wuyts
Dimitri Hemelsoet
Hilbert Pascale
Julie De Backer
Anne De Paepe
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CARDIOLOGY
2013
Questioning the pathogenic role of the GLA p.Ala143Thr 'mutation' in Fabry disease: implications for screening studies and ERT
Wim Terryn
Raymond Vanholder
Dimitri Hemelsoet
Bart Leroy
Wim Van Biesen
G De Schoenmakere
Brigitte Wuyts
Kathleen Claes
Julie De Backer
Anne De Paepe
et al.
Bookchapter
in
JIMD reports : case and research reports 2012/5
2013
Screening for Fabry disease: indications, methods and implications
Wim Terryn
Raymond Vanholder
Bruce Poppe
Dissertation
2013
Variant ataxia telangiectasia: clinical and molecular findings and evaluation of radiosensitive phenotypes in a patient and relatives
Kathleen Claes
Julie Depuydt
A Malcolm R Taylor
James I Last
Annelot Baert
Peter Schietecatte
Veerle Vandersickel
Bruce Poppe
Kim De Leeneer
Marc D'Hooghe
et al.
A1
Journal Article
in
NEUROMOLECULAR MEDICINE
2013
2012
Adults with Down syndrome: health/care considerations for health professionals
Barbara Delle Chiaie
S Van den Braembussche
C Elsing
S van den Ent
Roos Leroy
Bert Callewaert
M Wojciechowski
Bruce Poppe
G Van Buggenhout
G Van Goethem
A2
Journal Article
in
TIJDSCHRIFT VAN DE BELGISCHE KINDERARTS = JOURNAL DU PEDIATRE BELGE
2012
Association of PHB 1630 C > T and MTHFR 677 C > T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study
A Jakubowska
D Rozkrut
A Antoniou
U Hamann
RJ Scott
L McGuffog
S Healy
OM Sinilnikova
G Rennert
F Lejbkowicz
et al.
A1
Journal Article
in
BRITISH JOURNAL OF CANCER
2012
Characterization of LEDGF/p75 genetic variants and association with HIV-1 disease progression
Peter Messiaen
Ward De Spiegelaere
Jose Alcami
Karen Vervisch
Petra Van Acker
Bruno Verhasselt
Pieter Meuwissen
Esther Calonge
Nuria Gonzalez
Felix Gutierrez-Rodero
et al.
A1
Journal Article
in
PLOS ONE
2012
Comprehensive characterization of LEDGF/p75 in a HIV-1 infected patient cohort
Peter Messiaen
Ward De Spiegelaere
Jose Alcami
Paul Coucke
Petra Van Acker
Karen Vervisch
Bruno Verhasselt
Pieter Meeuwissen
Bruce Poppe
Dirk Vogelaers
et al.
C3
Conference
2012
Evaluation of RAD51C as cancer susceptibility gene in a large breast-ovarian cancer patient population referred for genetic testing
Kim De Leeneer
Mieke Van Bockstal
Sara De Brouwer
NATALIA SWIETEK
Peter Schietecatte
N Sabbaghian
J Van den Ende
S Willocx
K Storm
B Blaumeiser
et al.
A1
Journal Article
in
BREAST CANCER RESEARCH AND TREATMENT
2012
High-risk clonal evolution in chronic B-lymphocytic leukemia: single-center interphase fluorescence in situ hybridization study and review of the literature
Ann Janssens
Nadine Van Roy
Bruce Poppe
Lucien Noens
Jan Philippé
Franki Speleman
Fritz Offner
A1
Journal Article
in
EUROPEAN JOURNAL OF HAEMATOLOGY
2012
Matepair sequencing for the detection of chromosomal aberrations in patients with intellectual disability and congenital malformations
Sarah Vergult
Ellen Van Binsbergen
Tom Sante
Silke Nowak
Olivier Vanakker
Kathleen Claes
Bruce Poppe
Nathalie Van der Aa
MJ Van Roosmalen
K Duran
et al.
C3
Conference
2012
Mutation analysis of RAD51D in non-BRCA1/2 ovarian and breast cancer families
DJ Osher
Kim De Leeneer
G Michils
N Hamel
E Tomiak
Bruce Poppe
K Leunen
E Legius
A Shuen
E Smith
et al.
A1
Journal Article
in
BRITISH JOURNAL OF CANCER
2012
Prevalence of BRCA1/2 mutations in sporadic breast/ovarian cancer patients and identification of a novel de novo BRCA1 mutation in a patient diagnosed with late onset breast and ovarian cancer: implications for genetic testing
Kim De Leeneer
Ilse Coene
Brecht Crombez
Justine Simkens
Rudy Van den Broecke
Alain Bols
Barbara Stragier
Ilse Vanhoutte
Anne De Paepe
Bruce Poppe
et al.
A1
Journal Article
in
BREAST CANCER RESEARCH AND TREATMENT
2012
2011
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)
Evelien Mets
Joni Van der Meulen
Konstantinos J Mavrakis
Andrew L Wolfe
Tom Taghon
Aly A Khan
Manu Setty
Xiaoping Liu
Pieter Rondou
Peter Vandenberghe
et al.
C3
Conference
2011
Combined effect of polymorphisms in Rad51 and XRCC3 on breast cancer risk and chromosomal radiosensitivity
Anne Vral
Petra Willems
Kathleen Claes
Bruce Poppe
Ans Baeyens
Gianpaolo Perletti
Hubert Thierens
A1
Journal Article
in
MOLECULAR MEDICINE REPORTS
2011
Comprehensive characterization of LEDGF/p75 in a HIV-1-infected patient cohort
Peter Messiaen
Ward De Spiegelaere
Chris Verhofstede
Paul Coucke
Petra Van Acker
Philip Vlummens
KAREN VERVISCH
Dirk Vogelaers
Bruce Poppe
Jose Alcami
et al.
C3
Conference
2011
EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells
An De Weer
Joni Van der Meulen
Pieter Rondou
Tom Taghon
Torsten A Konrad
Katleen De Preter
Pieter Mestdagh
Tom Van Maerken
Nadine Van Roy
Marta Jeison
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2011
Evaluation of RAD51C as a new breast cancer suceptibility gene in Belgian/Dutch population
Kim De Leeneer
M Van Bockstael
NATALIA SWIETEK
J Van den Ende
K Storm
B Blaumeiser
K Leunens
CJ van Asperen
JT Wijnen
E Legius
et al.
C3
Conference
2011
Familial adenomatous polyposis: clinical presentation, detection and surveillance
Stéphanie Laurent
D Franchimont
JP Coppens
K Leunen
L Macken
Marc Peeters
O Plomteux
M Polus
Bruce Poppe
C Sempoux
et al.
A1
Journal Article
in
ACTA GASTRO-ENTEROLOGICA BELGICA
2011
Massive parallel amplicon sequencing of the breast cancer genes BRCA1 and BRCA2: opportunities, challenges, and limitations
Kim De Leeneer
Jan Hellemans
Joachim De Schrijver
Machteld Baetens
Bruce Poppe
Wim Van Criekinge
Anne De Paepe
Paul Coucke
Kathleen Claes
A1
Journal Article
in
HUMAN MUTATION
2011
Regulatory networks governed by microRNAs in T-ALL oncogenesis and normal T-cell development
Joni Van der Meulen
Evelien Mets
Pieter Mestdagh
Peter Pipelers
Tom Taghon
David Camacho Trujillo
David Avran
Gert Van Peer
Nadine Van Roy
Olivier Thas
et al.
C3
Conference
2011
The relationship between genetic testing, psychological well-being and surveillance behavior: a questionnaire study in presymptomatic female and male BRCA carriers and non-carriers
Katrien Verhoeven
Philippe De Wilde
Bruce Poppe
Anne De Paepe
Geert Crombez
A1
Journal Article
in
PSYCHOLOGIE & GEZONDHEID
2011
2010
Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction
Antonio C Antoniou
Jonathan Beesley
Lesley McGuffog
Olga M Sinilnikova
Sue Healey
Susan L Neuhausen
Yuan Chung Ding
Timothy R Rebbeck
Jeffrey N Weitzel
Henry T Lynch
et al.
A1
Journal Article
in
CANCER RESEARCH
2010
Identification of two critically deleted regions within chromosome segment 7q35-q36 in EVI1 deregulated myeloid leukemia cell lines
An De Weer
Bruce Poppe
Sarah Vergult
Pieter Van Vlierberghe
Marjan Petrick
Robrecht De Bock
Yves Benoit
Lucien Noens
Anne De Paepe
Nadine Van Roy
et al.
A1
Journal Article
in
PLOS ONE
2010
Kanker en erfelijkheid : van moleculaire diagnostiek tot psychologische begeleiding
Philippe De Wilde
Kathleen Claes
Kim De Leeneer
Bruce Poppe
Anne De Paepe
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2010
PHF6 mutations in T-cell acute lymphoblastic leukemia
Pieter Van Vlierberghe
Teresa Palomero
Hossein Khiabanian
Joni Van der Meulen
Mireia Castillo
Nadine Van Roy
Barbara De Moerloose
Jan Philippé
Sara Gonzalez-Garcia
Maria L Toribio
et al.
A1
Journal Article
in
NATURE GENETICS
2010
Wide diversity of PAX5 alterations in B-ALL: a Groupe Francophone de Cytogénétique Hématologique study
Etienne Coyaud
Stephanie Struski
Nais Prade
Julien Familiades
Ruth Eichner
Cathy Quelen
Marina Bousquet
Francine Mugneret
Pascaline Talmant
Marie-Pierre Pages
et al.
A1
Journal Article
in
BLOOD
2010
2009
Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs
Pieter Van Vlierberghe
An De Weer
Pieter Mestdagh
Tom Feys
Katleen De Preter
Anne De Paepe
Kathleen Lambein
Jo Vandesompele
Nadine Van Roy
Bruno Verhasselt
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2009
Downregulation of miR-449a is essential for the survival of EVI1 positive leukemic cells through modulation of NOTCH1 and BCL2
An De Weer
Pieter Mestdagh
Katleen De Preter
Joni Van der Meulen
Pieter Van Vlierberghe
Tom Van Maerken
Nadine Van Roy
Marta Jeison
Isaac Yaniv
Barbara Cauwelier
et al.
C3
Conference
2009
Genome profiling of acute myelomonocytic leukemia: alteration of the MYB locus in MYST3-linked cases
A Murati
C Gervais
N Carbuccia
P Finetti
N Cervera
J Adelaide
S Struski
E Lippert
F Mugneret
I Tigaud
et al.
A1
Journal Article
in
LEUKEMIA
2009
Genotyping of Frequent BRCA1/2 SNPs with Unlabeled Probes A Supplement to HRMCA Mutation Scanning, Allowing the Strong Reduction of Sequencing Burden
Kim De Leeneer
Ilse Coene
Bruce Poppe
Anne De Paepe
Kathleen Claes
A1
Journal Article
in
JOURNAL OF MOLECULAR DIAGNOSTICS
2009
MICRORNA SIGNATURES IN GENETIC SUBTYPES OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Joni Van der Meulen
Pieter Van Vlierberghe
Pieter Mestdagh
Jo Vandesompele
Bruce Poppe
Nadine Van Roy
Tom Taghon
Jean Plum
B. Cauwelier
DLD Selleslag
et al.
C3
Conference
2009
MODULATION OF MIR-449A EXPRESSION DECREASES CELL VIABILITY, INCREASES APOPTOSIS AND INDUCES DIFFERENTIATION IN EVI1 DEREGULATED LEUKEMIA CELLS
An De Weer
Bruce Poppe
Pieter Mestdagh
Katleen De Preter
Pieter Van Vlierberghe
Nadine Van Roy
M Jeison
B Cauwelier
Bruno Verhasselt
Jan Philippé
et al.
C3
Conference
2009
2008
Acute myeloid leukaemia with 8p11 (MYST3) rearrangement: an integrated cytologic, cytogenetic and molecular study by the groupe francophone de cytogenetique de hematologique
C GERVAIS
A MURATI
C HELIAS
S STRUSKI
A EISCHEN
E LIPPERT
I TIGAUD
D PENTHER
C BASTARD
F MUGNERET
et al.
A1
Journal Article
in
LEUKEMIA
2008
Copy number alterations and copy number variation in cancer: close encounters of the bad kind
Franki Speleman
Candy Kumps
Karen Buysse
Bruce Poppe
Björn Menten
Katleen De Preter
A1
Journal Article
in
CYTOGENETIC AND GENOME RESEARCH
2008
EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22
An De Weer
Franki Speleman
Barbara Cauwelier
Nadine Van Roy
Nurten Yigit
Bruno Verhasselt
Barbara De Moerloose
Yves Benoit
Lucien Noens
Dominik Selleslag
et al.
A1
Journal Article
in
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL
2008
EVII activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22)
An De Weer
Bruce Poppe
Barbara Cauwelier
A CARLIER
J DIERICK
Bruno Verhasselt
Jan Philippé
Nadine Van Roy
Franki Speleman
A1
Journal Article
in
BMC CANCER
2008
MICRORNA PROFILING OF EVI1 DEREGULATED MYELOID LEUKEMIA
An De Weer
Bruce Poppe
Pieter Mestdagh
Pieter Van Vlierberghe
Nadine Van Roy
Anne De Paepe
Bruno Verhasselt
Jo Vandesompele
Franki Speleman
C3
Conference
2008
MicroRNA signatures in genetic subtypes of T-cell acute lymphoblastic leukemia.
Pieter Van Vlierberghe
Bruce Poppe
Nadine Van Roy
Tom Taghon
Jean Plum
B Cauwelier
D Selleslag
P Heimann
P Vandenberghe
N Dastugue
et al.
C3
Conference
2008
Polymorphisms in nonhomologous end-joining genes associated with breast cancer risk and chromosomal radiosensitivity
Petra Willems
Kathleen Claes
Ans Baeyens
Veerle Vandersickel
Joke Werbrouck
Kim De Ruyck
Bruce Poppe
Rudy Van den Broecke
Amin Makar
Emanuela Marras
et al.
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2008
Rapid and sensitive detection of BRCA1/2 mutations in a diagnostic setting: Comparison of two high-resolution melting platforms
Kim De Leeneer
Ilse Coene
Bruce Poppe
Anne De Paepe
Kathleen Claes
A1
Journal Article
in
CLINICAL CHEMISTRY
2008
Two-tier approach for the detection of alpha-galactosidase A deficiency in a predominantly female haemodialysis population
W TERRYN
Bruce Poppe
B WUYTS
Kathleen Claes
B MAES
D VERBEELEN
Raymond Vanholder
K DE BOECK
Norbert Lameire
Anne De Paepe
et al.
A1
Journal Article
in
NEPHROLOGY DIALYSIS TRANSPLANTATION
2008
Two-tier approach for the detection of alpha-galactosidase A deficiency in kidney transplant recipients
Gert De Schoenmakere
Bruce Poppe
Birgitte Wuyts
Kathleen Claes
David Cassiman
Bart Maes
Dierik Verbeelen
Raymond Vanholder
Dirk R. Kuypers
Norbert Lameire
et al.
A1
Journal Article
in
NEPHROLOGY DIALYSIS TRANSPLANTATION
2008
2007
A detailed inventory of DNA copy number alterations in four commonly used Hodgkin lymphoma cell lines
Tom Feys
Bruce Poppe
Katleen De Preter
Nadine Van Roy
Bruno Verhasselt
Pascale De Paepe
Anne De Paepe
Franki Speleman
C3
Conference
2007
A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines
Tom Feys
Bruce Poppe
Katleen De Preter
Nadine Van Roy
Bruno Verhasselt
Pascale De Paepe
Anne De Paepe
Franki Speleman
A1
Journal Article
in
HAEMATOLOGICA
2007
Acquired chromosomal rearrangements targeting selected transcription factors: contribution of molecular cytogenetic and expression analyses to the identification of clinically and biologically relevant subgroups in hematological malignancies
Bruce Poppe
Anne De Paepe
Franki Speleman
A4
Journal Article
in
VERHANDELINGEN VAN DE KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIË
2007
Borstkanker en erfelijkheid
Bruce Poppe
Philippe De Wilde
Anne De Paepe
Bookchapter
in
Mijn borst : alles over borstchirurgie
2007
Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCR β-HOXA rearrangement : a study of the Groupe Francophone de Cytogénétique Hématologique
Barbara Cauwelier
H Cavé
C Gervais
M Lessard
C Barin
C Perot
J Van den Akker
F Mugneret
C Charrin
MP Pagès
et al.
A1
Journal Article
in
LEUKEMIA
2007
De bijdrage van M-FISH aan de moleculaire diagnostiek in de hemato-oncologie
Bruce Poppe
Nadine Van Roy
Nurten Yigit
Anne De Paepe
Franki Speleman
A2
Journal Article
in
Ned Tijdschr Hematol
2007
Identification of EVI1 transcriptional target genes using RNAI
An De Weer
Bruce Poppe
B CAUWEUER
Nadine Van Roy
Bruno Verhasselt
Franki Speleman
C3
Conference
2007
MicroRNA profiling of EVI1 deregulated myeloid leukemia
An De Weer
Bruce Poppe
Pieter Mestdagh
Nadine Van Roy
Anne De Paepe
Bruno Verhasselt
Jo Vandesompele
Franki Speleman
C3
Conference
2007
Preliminary screening results for fabry disease in young stroke patients reveals a new mutation
Dimitri Hemelsoet
Bruce Poppe
Anne Sieben
FREDERIK VANHEE
PASCAL PROOT
M De Clerck
Bart Leroy
Julie De Backer
Birgit Wuyts
LJ De Meirleir
et al.
C3
Conference
2007
Report of an unusual translocation t(3;14)(q26;q32) involving both EVI1 and IGH in an unclassified acute myeloid leukaemia (AML)
V HAVELANGE
G AMEYE
A DEWEER
K BAHLOULA
C MULLIER
JM LIBOUTON
M DETRAIT
P SAUSSOYS
Bruce Poppe
Franki Speleman
et al.
C3
Conference
2007
2006
EVII is consistently expressed as principal transcript in common and rare recurrent 3q26 rearrangements
Bruce Poppe
N DASTUGUE
Jo Vandesompele
Barbara Cauwelier
B DE SMET
Nurten Yigit
Anne De Paepe
J CERVERA
C RECHER
V DE MAS
et al.
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2006
GAB2 is a novel target of 11q amplification in AML/MDS
A ZATKOVA
C SCHOCH
Franki Speleman
Bruce Poppe
C MANNHALTER
C FONATSCH
K WIMMER
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2006
Molecular cytogenetic study of 126 unselected T-ALL cases reveals high incidence of TCR beta locus rearrangements and putative new T-cell oncogenes
Barbara Cauwelier
N DASTUGUE
J COOLS
Bruce Poppe
C HERENS
Anne De Paepe
A HAGEMEIJER
Franki Speleman
A1
Journal Article
in
LEUKEMIA
2006
Recurrent T(3;17)translocations in AML with EVI1 rearrangement
An De Weer
Bruce Poppe
B Cauwelier
Nadine Van Roy
N DASTUGUE
Barbara De Moerloose
Yves Benoit
Lucien Noens
Anne De Paepe
Franki Speleman
C3
Conference
2006
Recurrent t(3;17) translocations in AML with EVII rearrangement.
A De Weer
Bruce Poppe
B Cauwelier
Nadine Van Roy
N Dastugue
Barbara De Moerloose
Yves Benoit
Lucien Noens
Anne De Paepe
Franki Speleman
C3
Conference
2006
Screening for EVII: ectopic expression absent in T-cell acute lymphoblastic leukemia patients and cell lines
An De Weer
Bruce Poppe
B Cauwelier
Nadine Van Roy
N DASTUGUE
A HAGEMEIJER
Anne De Paepe
Franki Speleman
A1
Journal Article
in
CANCER GENETICS AND CYTOGENETICS
2006
2005
A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias
Franki Speleman
Barbara Cauwelier
N DASTUGUE
J COOLS
Bruno Verhasselt
Bruce Poppe
Nadine Van Roy
Jo Vandesompele
C GRAUX
A UYTTEBROECK
et al.
A1
Journal Article
in
LEUKEMIA
2005
Acquired chromosomal rearrangements targeting selected transcription factors: contribution of molecular cytogenetic and expression analyses to the identification of clinically and biologically relevant subgroups in hematological malignancies
Bruce Poppe
Franki Speleman
Anne De Paepe
Dissertation
2005
HOYA gene cluster rearrangement in a t(7;9)(p15;q34) in a child with MDS
Bruce Poppe
Nurten Yigit
Barbara De Moerloose
Anne De Paepe
Yves Benoit
Franki Speleman
A1
Journal Article
in
CANCER GENETICS AND CYTOGENETICS
2005
Novel cryptic chromosomal rearrangements in childhood acute lymphoblastic leukemia detected by multiple color fluorescent in situ hybridization
Bruce Poppe
Barbara Cauwelier
H VAN LIMBERGEN
Nurten Yigit
Jan Philippé
Bruno Verhasselt
Anne De Paepe
Yves Benoit
Franki Speleman
A1
Journal Article
in
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL
2005
PAX5/IGH rearrangement is a recurrent finding in a subset of aggressive B-NHL with complex chromosomal rearrangements
Bruce Poppe
P DE PAEPE
L MICHAUX
N DASTUGUE
C BASTARD
C HERENS
ELS MOREAU
F CAVAZZINI
Nurten Yigit
H VAN LIMBERGEN
et al.
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2005
Rapid detection of VHL exon deletions using real-time quantitative PCR
Jasmien Hoebeeck
R VAN DER LUIJT
Bruce Poppe
Els De Smet
Nurten Yigit
Kathleen Claes
R ZEWALD
GJ DE JONG
Anne De Paepe
Franki Speleman
et al.
A1
Journal Article
in
LABORATORY INVESTIGATION
2005
Recente moleculaire inzichten in erfelijke borst- en ovariumkanker in België
Kathleen Claes
Bruce Poppe
Ilse Coene
L MESSIAEN
Anne De Paepe
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2005
2004
BRCA1 and BRCA2 germline mutation spectrum and frequencies in Belgian breast/ovarian cancer families
Kathleen Claes
Bruce Poppe
Ilse Coene
Anne De Paepe
Ludwine Messiaen
A1
Journal Article
in
BRITISH JOURNAL OF CANCER
2004
Chromosomal radiosensitivity in BRCA1 and BRCA2 mutation carriers
Ans Baeyens
Hubert Thierens
Kathleen Claes
Bruce Poppe
Leo De Ridder
Anne Vral
A1
Journal Article
in
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
2004
Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951
H CAVÉ
S SUCIU
C PREUDHOMME
Bruce Poppe
A ROBERT
A UYTTEBROECK
M MALET
P BOUTARD
Yves Benoit
L MAUVIEUX
et al.
A1
Journal Article
in
BLOOD
2004
Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies
Bruce Poppe
Jo Vandesompele
C SCHOCH
C LINDVALL
K MROZEK
CD BLOOMFIELD
HB BEVERLOO
L MICHAUX
N DASTUGUE
C HERENS
et al.
A1
Journal Article
in
BLOOD
2004
Recommendations for the cytogenetic management of acute myeloblastic leukemia (AML) proposed by the Groupe Francais de Cytogenetique Hematologique (GFCH)
C BASTARD
L BARANGER
C BILHOU-NABERA
C CHARRIN
N DASTUGUE
V ECLACHE
M LAFAGE-POCHITALOFF
JL LAI
D LEROUX
M LESSARD
et al.
A1
Journal Article
in
PATHOLOGIE BIOLOGIE
2004
Recommendations for the cytogenetic management of adult and chidhoodacute lymphoblastic leukemia (ALL) proposed by the Groupe Francais de Cytogenetique Hematologique (GFCH)
L BARANGER
C BARI
C CHARRIN
P CORNILLET-LEFEBVRE
N DASTUGUE
M LAFAGE-POCHITALOFF
C PEROT
Bruce Poppe
S ROMANA
Franki Speleman
et al.
A1
Journal Article
in
PATHOLOGIE BIOLOGIE
2004
Recommendations for the cytogenetic management of myelodysplastic syndromes proposed by the Groupe Francais de Cytogenetique Hematologique (GFCH)
C BASTARD
I LUCQUET
MJ MOZZICONACCI
Bruce Poppe
S RAYNAUD
Franki Speleman
A1
Journal Article
in
PATHOLOGIE BIOLOGIE
2004
Routine microsatellite instability testing in sporadic colorectal tumours
Nancy Van Damme
Pieter Demetter
Kathleen Claes
Bruce Poppe
F BAERT
J ROELENS
Anne De Paepe
Claude Cuvelier
Marc Peeters
C3
Conference
2004
The impact of proband mediated information dissemination in families with a BRCA1/2 gene mutation
E SERMIJN
G GOELEN
E TEUGELS
L KAUFMAN
M BONDUELLE
B NEYNS
Bruce Poppe
Anne De Paepe
J DE GREVE
A1
Journal Article
in
JOURNAL OF MEDICAL GENETICS
2004
Translocation t(2;3)(p15-23;q26-27) in myeloid malignancies: report of 21 new cases, clinical, cytogenetic and molecular genetic features
M STEVENS-KROEF
Bruce Poppe
S VAN ZELDEREN-BHOLA
E VAN DEN BERG
M VAN DER BLIJ-PHILIPSEN
AG VAN KESSEL
R SLATER
G HAMERS
L MICHAUX
Franki Speleman
et al.
A1
Journal Article
in
LEUKEMIA
2004
2003
3q rearrangements in myeloid malignancies
Bruce Poppe
Nicole Dastugue
Franki Speleman
A2
Journal Article
in
ATLAS OF GENETICS AND CYTOGENETICS IN ONCOLOGY AND HAEMATOLOGY
2003
ALK activation by the CLTC-ALK fusion is a recurrent event in large B-cell lymphoma
P DE PAEPE
M BAENS
H VAN KRIEKEN
Bruno Verhasselt
M STUL
ANN SIMONS
Bruce Poppe
Genevieve Laureys
P BRONS
Pieter Vandenberghe
et al.
A1
Journal Article
in
BLOOD
2003
BRCA-genmutaties bij borstkanker
Bruce Poppe
Rudy Van den Broecke
Anne De Paepe
A2
Journal Article
in
PATIENT CARE (BELGIE NEDERLANDSE ED.)
2003
BRCA1/2 mutation spectrum and frequencies in Belgian breast/ovarian cancer families
Kathleen Claes
Bruce Poppe
Ilse Coene
Anne De Paepe
Ludwine Messiaen
C3
Conference
2003
Differentiating pathogenic mutations from polymorphic alterations in the splice sites of BRCA1 and BRCA2
Kathleen Claes
Bruce Poppe
E MACHACKOVA
Ilse Coene
L FORETOVA
Anne De Paepe
Ludwine Messiaen
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2003
Soft tissue tumors : clear cell sarcoma
Bruce Poppe
Ramses Forsyth
Karl Dhaene
Franki Speleman
A2
Journal Article
in
ATLAS OF GENETICS AND CYTOGENETICS IN ONCOLOGY AND HAEMATOLOGY
2003
Therapie van het colorectaal carcinoom : kunnen biologische merkers het beleid beïnvloeden?
B Sierens
Marc Peeters
Bruce Poppe
Anne De Paepe
Pieter Demetter
Claude Cuvelier
Martine De Vos
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2003
t(5;14)/HOX11L2-positive T-cell acute lymphoblastic leukemia. A collaborative study of the Groupe Francais de Cytogenetique Hematologique (GFCH)
R BERGER
N DASTUGUE
M BUSSON
J VAN DEN AKKER
C PEROT
P BALLERINI
A HAGEMEIJER
L MICHAUX
C CHARRIN
MP PAGES
et al.
A1
Journal Article
in
LEUKEMIA
2003
t(9;14)(p13;q32)
Bruce Poppe
Pascale De Paepe
Franki Speleman
A2
Journal Article
in
ATLAS OF GENETICS AND CYTOGENETICS IN ONCOLOGY AND HAEMATOLOGY
2003
2002
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
Jo Vandesompele
Katleen De Preter
Filip Pattyn
Bruce Poppe
Nadine Van Roy
Anne De Paepe
Franki Speleman
A1
Journal Article
in
GENOME BIOLOGY
2002
Chromosomal radiosensitivity in breast cancer patients with a known or putative genetic predisposition
Ans Baeyens
Hubert Thierens
Kathleen Claes
Bruce Poppe
Ludwine Messiaen
Leo De Ridder
Anne Vral
A1
Journal Article
in
BRITISH JOURNAL OF CANCER
2002
HOX11L2 expression linked to t(5;14)(q35;q32) is not associated with poor prognosis in childhood T-ALL treated in EORTC trials 58 881 and 58 951
H CAVÉ
S SUCIU
C PREUDHOMME
Bruce Poppe
A ROBERT
A UYTTEBROEK
M MALET
P BOUTARD
Yves Benoit
L MAUVIEUX
et al.
C3
Conference
2002
Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with complex karyotypes using M-FISH.
Heidi Van Limbergen
Bruce Poppe
L MICHAUX
C HERENS
J BROWN
Lucien Noens
Z BERNEMAN
R DE BOCK
Anne De Paepe
Franki Speleman
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2002
Meerkleuren fluorescentie in situ hybridisatie: methodologie en toepassingen in diagnostiek en onderzoek
Heidi Van Limbergen
Bruce Poppe
Stefan Vermeulen
Nadine Van Roy
Anne De Paepe
Franki Speleman
A4
Journal Article
in
TIJDSCHRIFT VAN DE BELGISCHE VERENIGING VAN LABORATORIUM-TECHNOLOGEN = REVUE DE L'ASSOCIATION BELGE DES TECHNOLOGUES DE LABORATOIRE
2002
Molecular cytogenetic analysis of 10;11 rearrangements in acute myeloid leukemia.
Heidi Van Limbergen
Bruce Poppe
A JANSSENS
R DE BOCK
Anne De Paepe
L NOENS
Franki Speleman
A1
Journal Article
in
LEUKEMIA
2002
Pathological splice mutations outside the invariant AG/GT splice sites of BRCA1 exon 5 increase alternative transcript levels in the 5 ' end of the BRCA1 gene.
Kathleen Claes
Jo Vandesompele
Bruce Poppe
K DAHAN
I COENE
Anne De Paepe
Ludwine Messiaen
A1
Journal Article
in
ONCOGENE
2002
Wanneer speelt erfelijkheid een rol
Anne De Paepe
Bruce Poppe
Bookchapter
in
Omgaan met darmkanker
2002
2001
Chromosomal aberrations in Bloom syndrome patients with myeloid malignancies.
Bruce Poppe
Heidi Van Limbergen
Nadine Van Roy
E VANDECRUYS
Anne De Paepe
Yves Benoit
Franki Speleman
A1
Journal Article
in
CANCER GENETICS AND CYTOGENETICS
2001
Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in neuroblastoma cell lines.
Nadine Van Roy
Heidi Van Limbergen
Jo Vandesompele
Mireille Van Gele
Bruce Poppe
H SALWEN
Genevieve Laureys
N MANOEL
Anne De Paepe
Franki Speleman
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2001
Genetisch advies bij het familiaal voorkomen van borstkanker
Bruce Poppe
I MEIRE
I DELVAUX
Kathleen Claes
L MESSIAEN
Anne De Paepe
A4
Journal Article
in
Guneikeïa
2001
Molecular characterization of a t(2;3)(p23;q26): A recurrent translocation involving the EVI1 gene
Bruce Poppe
Nurten Yigit
P MARYNEN
A HAGEMEIJER
H VAN LIMBERGEN
B DE SMET
Anne De Paepe
Franki Speleman
C3
Conference
2001
Molecular cytogenetic and clinical findings in ETV6/ABL1-positive leukemia.
Heidi Van Limbergen
HB BEVERLOO
E VAN DRUNEN
Ann Janssens
K HAHLEN
Bruce Poppe
Nadine Van Roy
P MARYNEN
Anne De Paepe
R SLATER
et al.
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2001
2000
Chromosome 2 short arm translocations revealed by M-FISH analysis of neuroblastoma cell lines.
Nadine Van Roy
Heidi Van Limbergen
Jo Vandesompele
Mireille Van Gele
Bruce Poppe
Genevieve Laureys
Anne De Paepe
Franki Speleman
A1
Journal Article
in
MEDICAL AND PEDIATRIC ONCOLOGY
2000
Familiale borst- en/of ovariumkanker: diagnostisch en predictief genetisch onderzoek
Isabelle Delvaux
M De Vos
Bruce Poppe
Geert Mortier
Anne De Paepe
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2000
Genetica en kanker: perspectieven voor diagnose en behandeling.
Franki Speleman
Bruce Poppe
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2000
Identification and characterisation of a founder mutation in the Belgian breast/ovarian cancer population
Kathleen Claes
Bruce Poppe
PETRA SCHEIR
M De Vos
I Delveaux
Ilse Coene
Anne De Paepe
Ludwine Messiaen
C3
Conference
2000
Repetitive analyses of P-glycoprotein in chronic myeloid leukaemia
Barbara De Moerloose
A Muylaert
F Gemmel
Anne Janssens
Bruce Poppe
Catharina Dhooge
Werner Van Hove
Jan Philippé
A1
Journal Article
in
ACTA CLINICA BELGICA
2000
1999
A single step real-time quantitative RT-PCR reaction for detection of the BCR/ABL fusion product
H VAN LIMBEREN
L VAN DE LOCHT
Bruce Poppe
Anne De Paepe
Fritz Offner
E MENSINK
Franki Speleman
C3
Conference
1999
Chromosome 7 short arm deletions and disease progression in CML
Bruce Poppe
H VAN LIMBERGEN
ANN JANSSENS
Nadine Van Roy
Barbara De Moerloose
J PHILLIPE
Anne De Paepe
Fritz Offner
Franki Speleman
C3
Conference
1999
Cytogenetic findings in bloom syndrome patients with myeloid malignancies
Bruce Poppe
Yves Benoit
H VAN LIMBERGEN
Nadine Van Roy
Els Vandecruys
A JAUCH
Anne De Paepe
J GERMAN
Franki Speleman
C3
Conference
1999
Genetic counselling and testing for hereditary breast and ovarian cancer: the gent(le) approach
M De Vos
Bruce Poppe
Isabelle Delvaux
Geert Mortier
Kathleen Claes
Ludwine Messiaen
Anne De Paepe
A1
Journal Article
in
DISEASE MARKERS
1999
Identification of a novel CBFB/MYH11 fusion in a patient with AML-M1 and a t(16;16)(p13;q22)
H VAN LIMBERGEN
B VAN DER REIJDEN
Bruce Poppe
Fritz Offner
Nadine Van Roy
H DAUWERSE
Anne De Paepe
Franki Speleman
C3
Conference
1999
Mutation analysis of the BRCA1 and BRCA2 genes in the Belgian patient population and identification of a Belgian founder mutation BRCA1 IVS5+3A > G
Kathleen Claes
E Machackova
Martine De Vos
Bruce Poppe
Anne De Paepe
Ludwine Messiaen
A1
Journal Article
in
DISEASE MARKERS
1999
Unusual chromosome 16 rearrangement with absence of classical CBFB/MYH11 fusion transcripts
H VAN LIMBERGEN
BA VAN DER REIJDEN
Bruce Poppe
Nadine Van Roy
H DAUWERSE
Anne De Paepe
Franki Speleman
C3
Conference
1999