Research Explorer

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Researcher

Bregje Leyman

Awards & Distinctions

39 Results

2018

Comparison of the expression kinetics and immunostimulatory activity of replicating mRNA, nonreplicating mRNA, and pDNA after intradermal electroporation in pigs

Bregje LeymanHanne HuysmansSéan Mc CaffertyFrancis CombesEric CoxBert DevriendtNiek Sanders

A1 Journal Article in MOLECULAR PHARMACEUTICS

2017

Evaluation of a xenogeneic vascular endothelial growth factor-2 vaccine in two preclinical metastatic tumor models in mice

Sofie DeniesBregje LeymanHanne HuysmansFrancis CombesSéan Mc CaffertyLaetitia CiccheleroMarjan SteppeJoyca De TemmermanNiek Sanders

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY

2016

Host stress drives Salmonella recrudescence

Elin VerbruggheMaarten DhaenensBregje LeymanFilip BoyenNeil ShearerAlexander Van ParysRoel HaesendonckWim BertHerman FavoreelDieter Deforce et al.

A1 Journal Article in SCIENTIFIC REPORTS

Host stress drives Salmonella recrudescence (vol 6, 20849, 2016)

Elin VerbruggheMaarten DhaenensBregje LeymanFilip BoyenNeil ShearerAlexander Van ParysRoel HaesendonckWim BertHerman FavoreelDieter Deforce et al.

Subtherapeutic tetracycline concentrations aggravate Salmonella Typhimurium infection by increasing bacterial virulence

Elin VerbruggheAlexander Van ParysRoel HaesendonckBregje LeymanFilip BoyenFreddy HaesebrouckFrank Pasmans

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

2015

Heat-labile enterotoxin of Escherichia coli promotes intestinal colonization of Salmonella enterica

Elin VerbruggheAlexander Van ParysBregje LeymanFilip BoyenSven ArnoutsUrban LundbergRichard DucatelleWim Van Den BroeckMaryam Atef YektaEric Cox et al.

A1 Journal Article in COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

HtpG contributes to Salmonella Typhimurium intestinal persistence in pigs

Elin VerbruggheAlexander Van ParysBregje LeymanFilip BoyenFreddy HaesebrouckFrank Pasmans

A1 Journal Article in VETERINARY RESEARCH

ScsA as a major driver for increased survival of Salmonella during a stress response

Elin VerbruggheMaarten DhaenensBregje LeymanFilip BoyenNeil ShearerAlexander Van ParysRoel HaesendonckWim BertHerman FavoreelDieter Deforce et al.

Subtherapeutic tetracycline concentrations aggravate Salmonella Typhimurium infection by increasing bacterial virulence

Elin VerbruggheAlexander Van ParysBregje LeymanFilip BoyenRoel HaesendonckFreddy HaesebrouckFrank Pasmans

2014

HtpG contributes to persistence of Salmonella in pigs

Elin VerbruggheFilip BoyenAlexander Van ParysBregje LeymanFreddy HaesebrouckFrank Pasmans

LT toxin of Escherichia coli promotes intestinal colonization of pigs with Salmonella

Elin VerbruggheFilip BoyenAlexander Van ParysBregje LeymanRichard DucatelleWim Van Den BroeckEric CoxFreddy HaesebrouckFrank Pasmans

ScsA as a major driver for increased survival of Salmonella during a stress response

Elin VerbruggheMaarten DhaenensBregje LeymanFilip BoyenNeil ShearerAlexander Van ParysRoel HaesendonckWim BertHerman FavoreelDieter Deforce et al.

2013

Effect of a DIVA vaccine with and without in-feed use of coated calcium-butyrate on transmission of Salmonella Typhimurium in pigs

Lotte De RidderDominiek MaesJeroen DewulfFrank PasmansFilip BoyenFreddy HaesebrouckEstelle MérocStefan RoelsBregje LeymanPatrick Butaye et al.

A1 Journal Article in BMC VETERINARY RESEARCH

Induction of seroconversion and persistence of Salmonella Typhimurium in pigs are strain dependent

Alexander Van ParysFilip BoyenBregje LeymanElin VerbruggheDominiek MaesFreddy HaesebrouckFrank Pasmans

A1 Journal Article in COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

2012

A modified glucomannan mycotoxin-adsorbing agent counteracts the reduced weight gain and diminishes cecal colonization of Salmonella Typhimurium in T-2 toxin exposed pigs

Elin VerbruggheSiska CroubelsVirginie VandenbrouckeJoline GoossensPatrick De BackerMia EeckhoutSarah De SaegerFilip BoyenBregje LeymanAlexander Van Parys et al.

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

Optimizing vaccination of pigs against Salmonella Typhimurium

Bregje LeymanFrank PasmansFilip BoyenFreddy Haesebrouck

Salmonella Typhimurium induces SPI-1 and SPI-2 regulated and strain dependent downregulation of MHC II expression on porcine alveolar macrophages

Alexander Van ParysFilip BoyenElin VerbruggheBregje LeymanBram FlahouFreddy HaesebrouckFrank Pasmans

A1 Journal Article in VETERINARY RESEARCH

T-2 toxin induced Salmonella Typhimurium intoxication results in decreased Salmonella numbers in the cecum contents of pigs, despite marked effects on Salmonella-host cell interactions

Elin VerbruggheVirginie VandenbrouckeMaarten DhaenensNeil ShearerJoline GoossensSarah De SaegerMia EeckhoutKatharina D'HerdeArthur ThompsonDieter Deforce et al.

A1 Journal Article in VETERINARY RESEARCH

Tackling the issue of environmental survival of live Salmonella Typhimurium vaccines: deletion of the lon gene

Bregje LeymanFilip BoyenAlexander Van ParysElin VerbruggheFreddy HaesebrouckFrank Pasmans

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

The complex interplay between stress and bacterial infections in animals

Elin VerbruggheFilip BoyenWim GaastraLeonie BekhuisBregje LeymanAlexander Van ParysFreddy HaesebrouckFrank Pasmans

A1 Journal Article in VETERINARY MICROBIOLOGY

Vaccination of pigs reduces Salmonella Typhimurium numbers in a model mimicking pre-slaughter stress

Bregje LeymanFilip BoyenElin VerbruggheAlexander Van ParysFreddy HaesebrouckFrank Pasmans

A1 Journal Article in VETERINARY JOURNAL

2011

An update on pathogenesis and control of Salmonella infections in pigs

Filip BoyenFrank PasmansAlexander Van ParysElin VerbruggheBregje LeymanFreddy Haesebrouck

Application of the DIVA principle to Salmonella Typhimurium vaccines in pigs avoids interference with serosurveillance programmes

Bregje LeymanFilip BoyenAlexander Van ParysElin VerbruggheFreddy HaesebrouckFrank Pasmans

Application of the DIVA principle to Salmonella Typhimurium vaccines in pigs avoids interference with serosurveillance programmes

Bregje LeymanFreddy HaesebrouckFilip BoyenAlexander Van ParysElin VerbruggheFrank Pasmans

Double benefit: a modified glucomannan mycotoxin-adsorbing agent counteracts T-2 toxin related reduced weight gain and limits Salmonella Typhimurium infections in pigs

Elin VerbruggheSiska CroubelsVirginie VandenbrouckeJoline GoossensPatrick De BackerMia EeckhoutSarah De SaegerFilip BoyenBregje LeymanAlexander Van Parys et al.

Een gewijzigde glucomannaan mycotoxine binder en T2-toxine in het voeder verminderen de kolonisatie van Salmonella Typhimurium in varkens

Elin VerbruggheSiska CroubelsVirginie VandenbrouckeMia EeckhoutSarah De SaegerJoline GoossensPatrick De BackerBregje LeymanAlexander Van ParysFilip Boyen et al.

Effects of the mycotoxins deoxynivalenol and T-2 toxin on the pathogenesis of a Salmonella TYphimurium infection in pigs

Virginie VandenbrouckeElin VerbruggheSiska CroubelsAn MartelJoline GoossensKim Van DeunFilip BoyenArthur ThompsonNeil ShearerSarah De Saeger et al.

Salmonella Typhimurium LPS mutations for use in vaccines allowing differentiation of infected and vaccinated pigs

Bregje LeymanFilip BoyenAlexander Van ParysElin VerbruggheFreddy HaesebrouckFrank Pasmans

A1 Journal Article in VACCINE

Salmonella Typhimurium interferes with the humoral immune response in pigs

Alexander Van ParysFilip BoyenElin VerbruggheBregje LeymanBram FlahouDominiek MaesFreddy HaesebrouckFrank Pasmans

Stress induced Salmonella Typhimurium recrudescence in pigs coincides with cortisol induced increased intracellular proliferation in macrophages

Elin VerbruggheFilip BoyenAlexander Van ParysKim Van DeunSiska CroubelsArthur ThompsonNeil ShearerBregje LeymanFreddy HaesebrouckFrank Pasmans

A1 Journal Article in VETERINARY RESEARCH

T-2 toxin causes decreased intestinal colonization of Salmonella Typhimurium in pigs associated with altered gene expression

Elin VerbruggheVirginie VandenbrouckeSiska CroubelsMia EeckhoutSarah De SaegerJoline GoossensPatrick De BackerArthur ThompsonNeil ShearerBregje Leyman et al.

Tissue-specific Salmonella Typhimurium gene expression during persistence in pigs

Alexander Van ParysFilip BoyenBregje LeymanElin VerbruggheFreddy HaesebrouckFrank Pasmans

A1 Journal Article in PLOS ONE

Vaccination of pigs reduces Salmonella Typhimurium numbers in a model mimicking pre-slaughter stress

Bregje LeymanFilip BoyenElin VerbruggheAlexander Van ParysFreddy HaesebrouckFrank Pasmans

2010

How and why Salmonella Typhimurium circumvents seroconversion in pigs

Alexander Van ParysFilip BoyenElin VerbruggheBregje LeymanFreddy HaesebrouckFrank Pasmans

HtpG and STM4067 contribute to long-term Salmonella Typhimurium persistence in pigs

Alexander Van ParysFilip BoyenElin VerbruggheBregje LeymanFreddy HaesebrouckFrank Pasmans

Salmonella Typhimurium resides largely as an extracellular pathogen in porcine tonsils, independently of biofilm-associated genes csgA, csgD and adrA

Alexander Van ParysFilip BoyenJiri VolfElin VerbruggheBregje LeymanIvan RychlikFreddy HaesebrouckFrank Pasmans

Salmonella Typhimurium resides largely as an extracellular pathogen in porcine tonsils, independently of biofilm-associated genes csgA, csgD and adrA

Alexander Van ParysFilip BoyenJiri VolfElin VerbruggheBregje LeymanIvan RychlikFreddy HaesebrouckFrank Pasmans

A1 Journal Article in VETERINARY MICROBIOLOGY

State of the art: Recent insights in the mechanism of Salmonella persistence in pigs

Bregje LeymanFilip BoyenAlexander Van ParysElin VerbruggheFreddy HaesebrouckFrank Pasmans

2009

Persistent Salmonella Typhimurium infections in pigs

Filip BoyenAlexander Van ParysJiri VolfElin VerbruggheBregje LeymanIvan RychlikFrank PasmansFreddy Haesebrouck