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Researcher
Brecht De Paepe
Profile
Projects
Publications & Research Data
Activities
Awards & Distinctions
Patents
57
Results
2026
A scaffoldomics platform for modular in vivo enzyme colocalisation and its application to naringenin biosynthesis
Marte Elias
Brecht De Paepe
Julie Vanderstraeten
Babette Lamote
Marjan De Mey
Yves Briers
A1
Journal Article
in
MICROBIAL BIOTECHNOLOGY
2026
From natural modularity to full programmability : AI-shaped design principles for customizable transcription factor biosensors
Brecht De Paepe
Wouter Demeester
Jasmine De Baets
Marjan De Mey
C3
Conference
2026
2025
Biological switches : past and future milestones of transcription factor-based biosensors
Brecht De Paepe
Marjan De Mey
A1
Journal Article
in
ACS SYNTHETIC BIOLOGY
2025
Characterization and orthogonality assessment of two quorum sensing systems for synthetic biology applications
Jasmine De Baets
Brecht De Paepe
Marjan De Mey
A1
Journal Article
in
NEW BIOTECHNOLOGY
2025
Expanding the quorum sensing toolbox : promoter libraries and hybrid promoter for dynamic genetic circuits
Jasmine De Baets
Iréne Parmentier
Brecht De Paepe
Marjan De Mey
A1
Journal Article
in
NEW BIOTECHNOLOGY
2025
Expanding the toolbox of quorum sensing switches toward the creation of two-stage fermentation processes
Jasmine De Baets
Marjan De Mey
Brecht De Paepe
Dissertation
2025
To transcription and beyond : development and application of transcriptional tools for yeasts and archaea
Andries Peeters
Marjan De Mey
Brecht De Paepe
Eveline Peeters
Dissertation
2025
Unravelling the regulatory network behind chitin degradation in Serratia marcescens
Wouter Demeester
Brecht De Paepe
Chiara Guidi
Marjan De Mey
A1
Journal Article
in
BIOLOGICAL REVIEWS
2025
2024
A cross-bacterial gene expression toolbox : engineering orthogonal transcription to enable predictable genetic engineering in diverse bacterial hosts
Cara Deal
Daniel Ariza Calvo
Brecht De Paepe
Antoni Planas
Lien De Wannemaeker
Marjan De Mey
C3
Conference
2024
Delaying production with prokaryotic inducible expression systems
Jasmine De Baets
Brecht De Paepe
Marjan De Mey
A1
Journal Article
in
MICROBIAL CELL FACTORIES
2024
Domain swapping of LysR-type transcriptional regulators for the development of orthogonal biosensors
Wouter Demeester
Brecht De Paepe
Luna Declerck
Antoni Sauter Planas
Marjan De Mey
C3
Conference
2024
Fundamentals and exceptions of the LysR-type transcriptional regulators
Wouter Demeester
Brecht De Paepe
Marjan De Mey
A1
Journal Article
in
ACS SYNTHETIC BIOLOGY
2024
Harnessing quorum sensing systems for complex genetic circuitry
Jasmine De Baets
Iréne Parmentier
Brecht De Paepe
Marjan De Mey
C3
Conference
2024
Standardization and expansion of microbial cell sensors : harnessing the power of LysR-type transcriptional regulators
Wouter Demeester
Marjan De Mey
Brecht De Paepe
Antoni Planas
Dissertation
2024
Standardized and computer-aided design-build-test-learn for custom biosensor development
Brecht De Paepe
C3
Conference
2024
Towards a universal, predictable and tuneable gene expression toolbox : strategies for engineering orthogonal transcription in bacteria
Cara Deal
Daniel Ariza Calvo
Brecht De Paepe
Antoni Planas
Lien De Wannemaeker
Marjan De Mey
C3
Conference
2024
Unlocking the potential of quorum sensing systems for synthetic biology applications
Jasmine De Baets
Iréne Parmentier
Brecht De Paepe
Marjan De Mey
C3
Conference
2024
2023
Computational design of new-to-nature biological sensors : unlocking the full potential of transcriptional regulation for custom biosensor development
Brecht De Paepe
Wouter Demeester
Jasmine De Baets
Dries Duchi
Marjan De Mey
C3
Conference
2023
Engineering orthogonal transcription for the development of a cross-bacterial, orthogonal and tuneable gene expression toolbox
Cara Deal
Lien De Wannemaeker
Brecht De Paepe
Antoni Planas
Marjan De Mey
C3
Conference
2023
High-throughput in vivo screening of novel prokaryotic, metabolite-responsive transcription factors for biosensor development
Amber Bernauw
Indra Bervoets
Andries Peeters
Brecht De Paepe
Marjan De Mey
Eveline Peeters
C3
Conference
2023
MoBioS : modular platform technology for high-throughput construction and characterization of tunable transcriptional biological sensors
Wouter Demeester
Jasmine De Baets
Dries Duchi
Marjan De Mey
Brecht De Paepe
A1
Journal Article
in
BIOSENSORS-BASEL
2023
Promoter engineering to create quorum sensing-based genetic circuits
Jasmine De Baets
Brecht De Paepe
Marjan De Mey
C3
Conference
2023
Unlocking transcription factor-based biosensors for industrial biotechnology
Wouter Demeester
Brecht De Paepe
Antoni Planas
Marjan De Mey
C3
Conference
2023
2022
A cross-bacterial, orthogonal and tuneable gene expression toolbox for development of microbial cell factories in diverse bacterial hosts
Cara Deal
Lien De Wannemaeker
Brecht De Paepe
Antoni Planas
Marjan De Mey
C3
Conference
2022
Biosensor-driven, model-based optimization of the orthogonally expressed naringenin biosynthesis pathway
Maarten Van Brempt
Andries Peeters
Dries Duchi
Lien De Wannemaeker
Jo Maertens
Brecht De Paepe
Marjan De Mey
A1
Journal Article
in
MICROBIAL CELL FACTORIES
2022
Dynamic feedback regulation for efficient membrane protein production using a small RNA-based genetic circuit in Escherichia coli
Chiara Guidi
Lien De Wannemaeker
Jasmine De Baets
Wouter Demeester
Jo Maertens
Brecht De Paepe
Marjan De Mey
A1
Journal Article
in
MICROBIAL CELL FACTORIES
2022
Expanding the synthetic biology toolbox of Sulfolobus acidocaldarius, a thermoacidophilic Crenarchaeon
Andries Peeters
Pauline Pijpstra
David Sybers
Brecht De Paepe
Eveline Peeters
Marjan De Mey
C3
Conference
2022
Filling the void : high-throughput development and characterization of transcription-factor based biosensors
Wouter Demeester
Brecht De Paepe
Antoni Planas
Marjan De Mey
C3
Conference
2022
High-throughput development and characterization of transcription-factor based biosensors
Wouter Demeester
Brecht De Paepe
Antoni Planas
Marjan De Mey
C3
Conference
2022
In vivo screening for the identification and characterization of prokaryotic, metabolite-responsive transcription factors
Amber Bernauw
Indra Bervoets
Andries Peeters
Brecht De Paepe
Marjan De Mey
Eveline Peeters
C3
Conference
2022
New synthetic biology tools for the thermoacidophilic Archaeon Sulfolobus acidocaldarius
Andries Peeters
Pauline Pijpstra
David Sybers
Brecht De Paepe
Eveline Peeters
Marjan De Mey
C3
Conference
2022
New-to-nature biological sensors : unlocking the full potential of biological sensors beyond nature
Brecht De Paepe
C3
Conference
2022
Quorum sensing-based genetic circuits for the automated delay of microbial production
Jasmine De Baets
Brecht De Paepe
Marjan De Mey
C3
Conference
2022
Quorum sensing-based switches to bypass the growth-production trade-off in microbial cell factories
Jasmine De Baets
Brecht De Paepe
Marjan De Mey
C3
Conference
2022
Scaffolding for product yield maximization of fine chemicals in microbial cell factories
Marte Elias
Babette Lamote
Julie Vanderstraeten
Brecht De Paepe
Marjan De Mey
Yves Briers
C3
Conference
2022
Scaffolding for product yield maximization of fine chemicals in microbial cell factories
Marte Elias
Babette Lamote
Julie Vanderstraeten
Brecht De Paepe
Marjan De Mey
Yves Briers
C3
Conference
2022
SynBio extreme : expanding the synthetic biology toolbox of Sulfolobus acidocaldarius, a thermoacidophilic Crenarchaeon
Andries Peeters
Pauline Pijpstra
David Sybers
Brecht De Paepe
Eveline Peeters
Marjan De Mey
C3
Conference
2022
Unlocking the potential of non-model bacteria : a cross-bacterial gene expression toolbox
Cara Deal
Lien De Wannemaeker
Brecht De Paepe
Antoni Planas
Marjan De Mey
C3
Conference
2022
2021
Expanding the transcriptional toolbox of the Crenarchaeon Sulfolobus acidocaldarius
Andries Peeters
Pauline Pijpstra
David Sybers
Brecht De Paepe
Eveline Peeters
Marjan De Mey
C3
Conference
2021
Tuning automated switches to uncouple growth and production in Escherichia coli
Jasmine De Baets
Brecht De Paepe
Marjan De Mey
C3
Conference
2021
2020
Expanding the biosensor horizon
Wouter Demeester
Brecht De Paepe
Antoni Planas
Marjan De Mey
C3
Conference
2020
2019
Chimeric LysR-type transcriptional biosensors for customizing ligand specificity profiles toward flavonoids
Brecht De Paepe
Jo Maertens
Bartel Vanholme
Marjan De Mey
A1
Journal Article
in
ACS SYNTHETIC BIOLOGY
2019
Development of microbial cell factories for the production of chito-oligosaccharides
David Bauwens
Sofie Snoeck
Chiara Guidi
Dries Duchi
Brecht De Paepe
Jo Maertens
Marjan De Mey
C3
Conference
2019
2018
Development of N-acetylneuraminic acid responsive biosensors based on the transcriptional regulator NanR
Gert Peters
Brecht De Paepe
Lien De Wannemaeker
Dries Duchi
Jo Maertens
Jeroen Lammertyn
Marjan De Mey
A1
Journal Article
in
BIOTECHNOLOGY AND BIOENGINEERING
2018
Modularization and response curve engineering of a naringenin-responsive transcriptional biosensor
Brecht De Paepe
Jo Maertens
Bartel Vanholme
Marjan De Mey
A1
Journal Article
in
ACS SYNTHETIC BIOLOGY
2018
Standardization in synthetic biology : an engineering discipline coming of age
Thomas Decoene
Brecht De Paepe
Jo Maertens
Pieter Coussement
Gert Peters
Sofie De Maeseneire
Marjan De Mey
A1
Journal Article
in
CRITICAL REVIEWS IN BIOTECHNOLOGY
2018
Tailor-made transcriptional biosensors for optimising microbial production of specialised plant metabolites in Escherichia coli
Brecht De Paepe
Marjan De Mey
Bartel Vanholme
Dissertation
2018
Tailor-made transcriptional biosensors for optimizing microbial cell factories
Brecht De Paepe
C3
Conference
2018
2017
Microbial cell factories for the production of specialised plant metabolites
Frederik De Bruyn
Maarten Van Brempt
Brecht De Paepe
Jo Maertens
David Bauwens
Pieter Coussement
Chin Giaw Lim
Bradley Walter Biggs
Ryan Philippe
Parayil Kumaran Ajikumar
et al.
C3
Conference
2017
Tailor-made transcriptional biosensors for optimizing microbial cell factories
Brecht De Paepe
Jo Maertens
Bartel Vanholme
Marjan De Mey
C3
Conference
2017
Tailor-made transcriptional biosensors for optimizing microbial cell factories
Brecht De Paepe
Gert Peters
Pieter Coussement
Jo Maertens
Marjan De Mey
A1
Journal Article
in
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
2017
2016
Tailor-made transcriptional biosensors
Brecht De Paepe
Jo Maertens
Bartel Vanholme
Marjan De Mey
C3
Conference
2016
2015
Development of an in vivo glucosylation platform by coupling production to growth: production of phenolic glucosides by a glycosyltransferase of Vitis vinifera
Frederik De Bruyn
Brecht De Paepe
Jo Maertens
Joeri Beauprez
Pieter De Cocker
Stein Mincke
Christian Stevens
Marjan De Mey
A1
Journal Article
in
BIOTECHNOLOGY AND BIOENGINEERING
2015
2014
Biosensors and high throughput metabolic engineering for the production of specialized plant metabolites in E. coli
Brecht De Paepe
Bartel Vanholme
Marjan De Mey
C3
Conference
2014
Creating a novel and versatile glycosylation platform in E. coli
Frederik De Bruyn
Brecht De Paepe
Maarten Van Brempt
Pieter De Cocker
Jo Maertens
Joeri Beauprez
Wim Soetaert
Marjan De Mey
C3
Conference
2014
Multivariate modular metabolic engineering for pathway and strain optimization
Bradley Walters Biggs
Brecht De Paepe
Christine Nicole S Santos
Marjan De Mey
Parayil Kumaran Ajikumar
A1
Journal Article
in
CURRENT OPINION IN BIOTECHNOLOGY
2014
2013
Building a glucosylation platform in E. coli through Metabolic Engineering
Frederik De Bruyn
Brecht De Paepe
Joeri Beauprez
Jo Maertens
Wim Soetaert
Marjan De Mey
C3
Conference
2013