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Researcher
Bram Laukens
Profile
Projects
Publications
Activities
Awards & Distinctions
16
Results
2023
GlycoVHH : optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery
Loes van Schie
Wander Van Breedam
Charlotte Roels
Bert Schepens
Martin Frank
Ahmadreza Mehdipour
Bram Laukens
Wim Nerinckx
Francis Santens
Simon Devos
et al.
A1
Journal Article
in
MABS
2023
2022
GlycoVHH : introducing N-glycans on the camelid VHH antibody scaffold : optimal sites and use for macrophage delivery
Loes van Schie
Wander Van Breedam
Charlotte Roels
Bert Schepens
Martin Frank
Ahmadreza Mehdipour
Bram Laukens
Wim Nerinckx
Francis Santens
Simon Devos
et al.
Preprint
2022
2021
Knockout of RSN1, TVP18 or CSC1-2 causes perturbation of Golgi cisternae in Pichia pastoris
Rochelle Aw
Charlot De Wachter
Bram Laukens
Riet De Rycke
Michiel De Bruyne
David Bell
Nico Callewaert
Karen M. Polizzi
A1
Journal Article
in
TRAFFIC
2021
2020
Off-target glycans encountered along the synthetic biology route toward humanized N-glycans in Pichia pastoris
Bram Laukens
Pieter Jacobs
Katelijne Gheysen
José Martins
Charlot De Wachter
Paul Ameloot
Willy Morelle
Jurgen Haustraete
Jean-Christophe Renauld
Bart Samyn
et al.
A1
Journal Article
in
BIOTECHNOLOGY AND BIOENGINEERING
2020
2019
Yeast-secreted, dried and food-admixed monomeric IgA prevents gastrointestinal infection in a piglet model
Vikram Virdi
Jorge Palací Bataller
Bram Laukens
Stefan Ryckaert
Eric Cox
Erik Vanderbeke
Anna Depicker
Nico Callewaert
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2019
2018
Optimized expression of the Starmerella bombicola lactone esterase in Pichia pastoris through temperature adaptation, codon-optimization and co-expression with HAC1
Stijn De Waele
Isabel Vandenberghe
Bram Laukens
Sören Planckaert
Stijn Verweire
Inge Van Bogaert
Wim Soetaert
Bart Devreese
Katarzyna Ciesielska
A1
Journal Article
in
PROTEIN EXPRESSION AND PURIFICATION
2018
2017
A simple colorimetric assay for measuring fructosamine 3 kinase activity
Justin C Cikomola
Antoine S Kishabongo
Karl Vandepoele
MARIEKE DE MULDER
Philippe B Katchunga
Bram Laukens
Loes van Schie
Hendrik Grootaert
Nico Callewaert
Marijn Speeckaert
et al.
A1
Journal Article
in
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
2017
2016
A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris
Fabrice Cerini
Hubert Gaertner
Knut Madden
Ilya Tolstorukov
Scott Brown
Bram Laukens
Nico Callewaert
Jay C Harner
Anna M Oommen
John T Harms
et al.
A1
Journal Article
in
PROTEIN EXPRESSION AND PURIFICATION
2016
Modular integrated secretory system engineering in Pichia pastoris to enhance G-protein coupled receptor expression
Katrien Claes
Kristof Vandewalle
Bram Laukens
Toon Laeremans
Olivier Vosters
Ingrid Langer
Marc Parmentier
Jan Steyaert
Nico Callewaert
A1
Journal Article
in
ACS SYNTHETIC BIOLOGY
2016
N-glycosylation engineering in Pichia pastoris for protein therapeutics: advancing the GlycoSwitch and introducing GlycoDelete
Bram Laukens
Nico Callewaert
Dissertation
2016
2015
Comparison of VHH-Fc antibody production in Arabidopsis thaliana, Nicotiana benthamiana and Pichia pastoris
Thomas De Meyer
Bram Laukens
Jonah Nolf
Els Van Lerberge
Riet De Rycke
Ans De Beuckelaer
Sylvie De Buck
Nico Callewaert
Anna Depicker
A1
Journal Article
in
PLANT BIOTECHNOLOGY JOURNAL
2015
Engineering the Pichia pastoris N-glycosylation pathway using the GlycoSwitch technology
Bram Laukens
Charlot De Wachter
Nico Callewaert
Bookchapter
in
Glyco-engineering : methods and protocols
2015
Engineering yeast for producing human glycoproteins : where are we now?
Bram Laukens
Charlotte De Visscher
Nico Callewaert
A1
Journal Article
in
FUTURE MICROBIOLOGY
2015
2011
Disruption of the SapM locus in Mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis
Nele Festjens
Pieter Bogaert
Anjana Batni
Erica Houthuys
Evelyn Plets
Dieter Vanderschaeghe
Bram Laukens
Bob Asselbergh
Eef Parthoens
Riet De Rycke
et al.
A1
Journal Article
in
EMBO MOLECULAR MEDICINE
2011
Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis
Bram Laukens
Claudia Jennewein
Barbara Schenk
Nele Vanlangenakker
Alexander Schier
Silvia Cristofanon
Kerry Zobel
Kurt Deshayes
Domagoj Vucic
Irmela Jeremias
et al.
A1
Journal Article
in
NEOPLASIA
2011
cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
Nele Vanlangenakker
Tom Vanden Berghe
Pieter Bogaert
Bram Laukens
K Zobel
K Deshayes
D Vucic
S Fulda
Peter Vandenabeele
Mathieu Bertrand
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2011