Research Explorer

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Researcher

Bram Bogaert

Awards & Distinctions

8 Results

2024

Combinatorial screening of biscarbamate ionizable lipids identifies a low reactogenicity lipid for lipid nanoparticle mRNA delivery

Emily De LombaerdeYong ChenTingting YeJulie DeckersGiulia MencarelliKim DeswarteHeleen LauwersRuben De CoenSabah KasmiSanne Bevers et al.

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

Selective replacement of cholesterol with cationic amphiphilic drugs enables the design of lipid nanoparticles with improved RNA delivery

Bram BogaertAliona DebisschopThomas EhouarneHannelore Van EeckhoutteJoyceline De VolderAn JacobsEline PottieRiet De RyckeAurélie CrabbéPieter Mestdagh et al.

A1 Journal Article in NANO LETTERS

2023

A lipid nanoparticle platform for RNA delivery with cationic amphiphilic drugs : merging the best of both worlds

Bram BogaertKoen RaemdonckStefaan De Smedt

Influence of the size and charge of carbon quantum dots on their corneal penetration and permeation enhancing properties

Inès De HoonAlexandre BarrasTomasz SwebockiBernd VanmeerhaegheBram BogaertCristina MunteanAmar AbderrahmaniRabah BoukherroubStefaan De SmedtFélix Sauvage et al.

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Mammalian target of rapamycin inhibition enhances delivery and activity of antisense oligonucleotides in uveal melanoma cells

Shanna DewaeleLouis DelhayeBoel De PaepeBram BogaertRamiro MartinezJasper AnckaertNurten YigitJustine NuytensRudy Van CosterSven Eyckerman et al.

A1 Journal Article in NUCLEIC ACID THERAPEUTICS

2022

A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs

Bram BogaertFelix SauvageRoberta GuagliardoCristina Muntean[missing] Van Phuc NguyenEline PottieMike WelsAn-Katrien MinnaertRiet De RyckeQiangbing Yang et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2020

Cationic amphiphilic drugs boost the lysosomal escape of small nucleic acid therapeutics in a nanocarrier-dependent manner

Thijs Van de VyverBram BogaertLynn De BackerFreya JorisRoberta GuagliardoJelter Van HoeckPieterjan MerckxSerge Van CalenberghSrinivas RamishettiDan Peer et al.

A1 Journal Article in ACS NANO

Lyophilization and nebulization of pulmonary surfactant-coated nanogels for siRNA inhalation therapy

Pieterjan MerckxJoris LammensGust NuyttenBram BogaertRoberta GuagliardoTania MaesChris VervaetThomas De BeerStefaan De SmedtKoen Raemdonck

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS