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Researcher
Bieke Bekaert
Profile
Projects
Publications
Activities
Awards & Distinctions
13
Results
2023
CRISPR/Cas9-based correction of infertility-related mutations in the germline : ready or not?
Bieke Bekaert
Björn Heindryckx
Annekatrien Boel
Björn Menten
Dissertation
2023
Retained chromosomal integrity following CRISPR-Cas9-based mutational correction in human embryos
Bieke Bekaert
Annekatrien Boel
Lisa De Witte
Winter Vandenberghe
Mina Popovic
Panagiotis Stamatiadis
Gwenny Cosemans
Lise Tordeurs
Athina-Maria De Loore
Susana Marina Chuva de Sousa Lopes
et al.
A1
Journal Article
in
MOLECULAR THERAPY
2023
2022
CRISPR/Cas gene editing in the human germline
Bieke Bekaert
Annekatrien Boel
Gwenny Cosemans
Lisa De Witte
Björn Menten
Björn Heindryckx
A1
Journal Article
in
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
2022
Distinct genetic impact of CRISPR/Cas9 gene correction in human embryos compared to induced pluripotent stem cells
Bieke Bekaert
Annekatrien Boel
Lisa De Witte
Gwenny Cosemans
Lise Tordeurs
Athina-Maria De Loore
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
Dominic Stoop
Paul Coucke
et al.
C3
Conference
2022
Evaluation of CRISPR/Cas9-induced DNA break repair outcomes in mouse and human embryos
Bieke Bekaert
Annekatrien Boel
Lisa De Witte
Gwenny Cosemans
Susana Marina Chuva de Sousa Lopes
Björn Menten
Björn Heindryckx
C3
Conference
2022
Human germline nuclear transfer to overcome mitochondrial disease and failed fertilization after ICSI
Maoxing Tang
Annekatrien Boel
Noemi Castelluccio
Arantxa Cardona Barberán
Antonia Christodoulaki
Bieke Bekaert
Mina Popovic
Frauke Vanden Meerschaut
Petra De Sutter
Björn Menten
et al.
A1
Journal Article
in
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
2022
2021
Comparative analysis of mouse and human preimplantation development following POU5F1 CRISPR/Cas9 targeting reveals interspecies differences
Panagiotis Stamatiadis
Annekatrien Boel
Gwenny Cosemans
Mina Popovic
Bieke Bekaert
Ramesh Guggilla
Maoxing Tang
Petra De Sutter
Filip Van Nieuwerburgh
Björn Menten
et al.
A1
Journal Article
in
HUMAN REPRODUCTION
2021
Correcting a PLCζ mutation in the human germ line to overcome hereditary infertility
Bieke Bekaert
Annekatrien Boel
Mina Popovic
Panagiotis Stamatiadis
S M Chuva de Sousa Lopes
Petra De Sutter
Björn Menten
Dominic Stoop
Paul Coucke
Björn Heindryckx
C3
Conference
2021
Engineering microvasculature by 3D bioprinting of prevascularized spheroids in photo-crosslinkable gelatin
Lise De Moor
Jasper Smet
Magaly Plovyt
Bieke Bekaert
Chris Vercruysse
Mahtab Asadian
Nathalie De Geyter
Sandra Van Vlierberghe
Peter Dubruel
Heidi Declercq
A1
Journal Article
in
BIOFABRICATION
2021
2020
A proof-of-concept study to investigate DNA repair mechanisms in the human embryo after the application of CRISPR/Cas9 gene editing in the germ line
Bieke Bekaert
Annekatrien Boel
Lisa De Witte
Mina Popovic
Ramesh Guggilla
Swati Mishra
Gwenny Cosemans
Lise Tordeurs
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
et al.
C3
Conference
2020
Correcting PLCζ mutation in the germ line to overcome transmission of hereditary infertility in mice
Bieke Bekaert
Annekatrien Boel
Vanessa Thys
Panagiotis Stamatiadis
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
John Parrington
Björn Menten
Dominic Stoop
Paul Coucke
et al.
C3
Conference
2020
Correcting a PLCζ mutation in the human germ line to overcome hereditary infertility
Bieke Bekaert
Annekatrien Boel
Mina Popovic
Panagiotis Stamatiadis
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
Paul Coucke
Björn Heindryckx
C3
Conference
2020
2018
Generation and bioprinting of prevascularized spheroids using a photo-crosslinkable gelatin
Lise De Moor
Idriz Merovci
Sarah Baetens
Bieke Bekaert
Julien Verstraeten
Paulina Kowalska
Sandra Van Vlierberghe
Peter Dubruel
Dmitri Krysko
Winnok De Vos
et al.
C3
Conference
2018