Research Explorer

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Researcher

Benoit Louage

Publications & Research Data

Awards & Distinctions

30 Results

2025

A genetically encoded endogenous antibody recruitment strategy for innate immune-mediated killing of cancer cells

Justine AelvoetZifu ZhongClaudia Mariela Brenis GómezHelena Catharine AegerterBenoit LouageBart LambrechtBruno De GeestMartijn Schuijs

A1 Journal Article in ADVANCED MATERIALS

Combinatorial synthesis and evaluation of trialkyl galloyl amidoamine ionizable lipids for mRNA formulation

Bianka GolbaIrene De FranceschiZifu ZhongMartijn SchuijsClaudia Mariela Brenis GómezHeleen LauwersBenoit LouageIasona SheshiNezha BadiBruno De Geest et al.

A1 Journal Article in JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhancing anti-tumor immunity through intratumoral combination therapy with amphiphilic conjugates of oxaliplatin and imidazoquinoline TLR7/8 agonist

Hanne VerschuereSabah KasmiLutz NuhnSènan Mickaël D'AlmeidaQiwen ZhuZifu ZhongSandy Adjemian CataniBenoit LouageJana De VriezeHaijun Yu et al.

A1 Journal Article in RSC ADVANCES

2024

HER2 nanobody-poly(rhamnose) conjugates efficiently recruit anti-rhamnose antibodies from serum to the surface of HER2-expressing cells

Weiwei MuYong ChenZifu ZhongBenoit LouageHeleen LauwersNick DevoogdtJurgen HaustraeteBruno De Geest

A1 Journal Article in CHEMISTRY OF MATERIALS

Lipid nanoparticle encapsulation empowers poly(I:C) to activate cytoplasmic RLRs and thereby increases its adjuvanticity

Alexander LamootSonia JangraGabriel LaghlaliPrajakta WarangLauren A. ChangSeok‐Chan ParkGagandeep SinghKim DeswarteZifu ZhongBenoit Louage et al.

A1 Journal Article in SMALL

Lysosomal trafficking and degradation of extracellular proteins via multivalent small molecule ligand display on dextran scaffolds

Benoit LouageDemi DefreyneHeleen LauwersJamie De BaereAnnemiek UvynHaixia PengYong ChenBruno De Geest

A1 Journal Article in BIOMACROMOLECULES

2023

Hapten/myristoyl functionalized poly(propyleneimine) dendrimers as potent cell surface recruiters of antibodies for mediating innate immune killing

Annemiek UvynMarle Elisabeth Jacqueline VleugelsBas de WaalAhmed Emad Ibrahim HamoudaShikha DhimanBenoit LouageLorenzo AlbertazziDamya LaouiE. W. MeijerBruno De Geest

A1 Journal Article in ADVANCED MATERIALS

2019

Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists

Jana De VriezeBenoit LouageKim DeswarteZifu ZhongRuben De CoenSimon Van HerckLutz NuhnCamilla Kaas FrichAlexander N ZelikinStefan Lienenklaus et al.

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Water-soluble Withaferin A polymer prodrugs via a drug-functionalized RAFT CTA approach

Simon Van HerckBehrouz HassanniaBenoit LouageRaquel Pita CompostizoRuben De CoenWim Vanden BergheTom Vanden BergheBruno De Geest

A1 Journal Article in EUROPEAN POLYMER JOURNAL

2018

A versatile method for the selective core-crosslinking of hyaluronic acid nanogels via ketone-hydrazide chemistry : from chemical characterization to in vivo biodistribution

Francielle Pelegrin GarciaMarlène RippeMychelle VP CompanhoniTalitha Fernandes StefanelloBenoit LouageSimon Van HerckLucie SanceyJean-Luc CollBruno De GeestCelso Vataru Nakamura et al.

A2 Journal Article in BIOMATERIALS SCIENCE

Transiently thermoresponsive acetal polymers for safe and effective administration of Amphotericin B as a vaccine adjuvant

Simon Van HerckLien Van HoeckeBenoit LouageLien LybaertRuben De CoenSabah KasmiAaron P Esser-KahnSunil A DavidLutz NuhnBert Schepens et al.

A1 Journal Article in BIOCONJUGATE CHEMISTRY

2017

Acrylamides with hydrolytically labile carbonate ester side chains as versatile building blocks for well-defined block copolymer micelles via RAFT polymerization

Sabah KasmiBenoit LouageLutz NuhnGlenn VerstraeteSimon Van HerckMies J van SteenbergenChris VervaetWim E HenninkBruno De Geest

A1 Journal Article in POLYMER CHEMISTRY

Amphiphilic ferrocene-containing PEG block copolymers as micellar nanocarriers and smart surfactants

Arda AlkanSarah WaldBenoit LouageBruno De GeestKatharina LandfesterFrederik R. Wurm

A1 Journal Article in LANGMUIR

Design, synthesis and evaluation of advanced polymeric taxane formulations

Benoit LouageBruno De Geest

Developments and future clinical outlook of taxane nanomedicines

Benoit LouageOlivier De WeverWim E HenninkBruno De Geest

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Micellar paclitaxel-initiated RAFT polymer conjugates with acid-sensitive behavior

Benoit LouageMies J. van SteenbergenLutz NuhnMartijn RisseeuwIzet KaralicJohan WinneSerge Van CalenberghWim E HenninkBruno De Geest

A1 Journal Article in ACS MACRO LETTERS

Poly(glycerol sebacate) nanoparticles for encapsulation of hydrophobic anti-cancer drugs

Benoit LouageLiesa TackYadong WangBruno De Geest

A1 Journal Article in POLYMER CHEMISTRY

2016

pH-Degradable mannosylated nanogels for dendritic cell targeting

Ruben De CoenNane VanparijsMartijn RisseeuwLien LybaertBenoit LouageStefaan De KokerVimal Kumar UdhayakumarJohan GrootenLeeanne TaylorNeil Ayres et al.

A1 Journal Article in BIOMACROMOLECULES

Transiently responsive block copolymer micelles based on N-(2-hydroxypropyl)methacrylamide engineered with hydrolyzable ethylcarbonate side chains

Sabah KasmiBenoit LouageLutz NuhnAlexandra Van DriesscheJan Van DeunIzet KaralicMartijn RisseeuwSerge Van CalenberghRichard HoogenboomRiet De Rycke et al.

A1 Journal Article in BIOMACROMOLECULES

Well-defined polymer-paclitaxel prodrugs by a grafting-from-drug approach

Benoit LouageLutz NuhnMartijn RisseeuwNane VanparijsRuben De CoenIzet KaralicSerge Van CalenberghBruno De Geest

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Wohldefinierte polymere Paclitaxel-Prodrugs über eine Grafting-From-Methode ausgehend vom Arzneistoff

Benoit LouageLutz NuhnMartijn RisseeuwNane VanparijsRuben De CoenIzet KaralicSerge Van CalenberghBRUNO DE GEEST

A2 Journal Article in ANGEWANDTE CHEMIE

2015

Acid-labile thermoresponsive copolymers that combine fast pH-triggered hydrolysis and high stability under neutral conditions

Qilu ZhangZhanyao HouBenoit LouageDingying ZhouNane VanparijsBruno De GeestRichard Hoogenboom

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Degradable ketal-based block copolymer nanoparticles for anticancer drug delivery : a systematic evaluation

Benoit LouageQilu ZhangNane VanparijsLenny VoorhaarSofie Vande CasteeleYang ShiWim E HenninkJan Van BocxlaerRichard HoogenboomBruno De Geest

A1 Journal Article in BIOMACROMOLECULES

Polymer-protein conjugation via a 'grafting to' approach: a comparative study of the performance of protein-reactive RAFT chain transfer agents

Nane VanparijsSamarendra MajiBenoit LouageLenny VoorhaarDuchan LaplaceQilu ZhangY ShiWim E HenninkRichard HoogenboomBruno De Geest

A1 Journal Article in POLYMER CHEMISTRY

Sequence-selective DNA recognition and enhanced cellular up-take by peptide–steroid conjugates

Yara Ruiz GarciaAbhishek IyerDorien Van LysebettenY Vladimir PabonBenoit LouageMalgorzata HoncharenkoBruno De GeestCI Edvard SmithRoger StrömbergAnnemieke Madder

A1 Journal Article in CHEMICAL COMMUNICATIONS

Stapling monomeric GCN4 peptides allows for DNA binding and enhanced cellular uptake

Abhishek IyerDorien Van LysebettenYara Ruiz GarciaBenoit LouageBruno De GeestAnnemieke Madder

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

Transiently responsive protein–polymer conjugates via a 'grafting-from' RAFT approach for intracellular co-delivery of proteins and immune-modulators

Nane VanparijsRuben De CoenDuchan LaplaceBenoit LouageSamarendra MajiLien LybaertRichard HoogenboomBruno De Geest

A1 Journal Article in CHEMICAL COMMUNICATIONS

2014

Dual pH- and temperature-responsive RAFT-based block co-polymer micelles and polymer-protein conjugates with transient solubility

Qilu ZhangNane VanparijsBenoit LouageBruno De GeestRichard Hoogenboom

A1 Journal Article in POLYMER CHEMISTRY

2013

Dual temperature- and pH-responsive polymers for protein conjugation and vaccine design

Bruno De GeestQilu ZhangNane VanparijsBenoit LouageZhiyue ZhangRichard Hoogenboom

Magnetically engineered microcapsules as intracellular anchors for remote control over cellular mobility

Anton M PavlovBruno De GeestBenoit LouageLien LybaertStefaan De KokerZdenek KoudelkaAndrei V SapelkinGleb B Sukhorukov

A1 Journal Article in ADVANCED MATERIALS