Research Explorer

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Researcher

Bart Vanhaesebroeck

Awards & Distinctions

13 Results

1995

Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells

Peter VandenabeeleWim DeclercqBart VanhaesebroeckJohan GrootenWalther Fiers

A2 Journal Article in J. Immunol.. 154, pp. 2904-2913

Casein kinase-1 phosphorylates the p75 tumor-necrosis-factor receptor and negatively regulates tumor-necrosis-factor signaling for apoptosis.

Rudi BeyaertBart VanhaesebroeckWim DeclercqJ VANLINTPeter VandenabeeleP AGOSTINISJR VANDENHEEDEWalther Fiers

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Generation and biological characterization of membrane-bound, uncleavable murine tumor-necrosis factor.

Els DecosterBart VanhaesebroeckPeter VandenabeeleJohan GrootenWalther Fiers

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

POLAR AGENTS WITH DIFFERENTIATION-INDUCING CAPACITY POTENTIATE TUMOR NECROSIS FACTOR-MEDIATED CYTOTOXICITY IN HUMAN MYELOID CELL-LINES.

S DEPRAETEREBart VanhaesebroeckWalther FiersJan WillemsM JONIAU

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

1993

Effect of bcl-2-proto-oncogene expression on cellular sensitivity to tumor necrosis factor-mediated cytotoxicity.

Bart VanhaesebroeckJC REEDD DEVALCKJohan GrootenT MIYASHITAS TANAKARudi BeyaertFrans Van RoyWalther Fiers

A1 Journal Article in ONCOGENE

Sensitization of tumor cells to tumor necrosis factor action by the protein kinase inhibitor staurosporine

Rudi BeyaertBart VanhaesebroeckKaren HeyninckElke BooneDirk De ValckKlaus Schulze-OsthoffGuy HaegemanFrans Van RoyWalther Fiers

A1 Journal Article in CANCER RESEARCH

Two pathways of tumor necrosis factor signal transduction: in vitro and in vivo implications

Walther FiersRudi BeyaertPeter BrouckaertAnje CauwelsWim DeclercqDirk De ValckB EveraerdtVera GoossensJohan GrootenGuy Haegeman et al.

1992

Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation.

K SCHULZEOSTHOFFAC BAKKERBart VanhaesebroeckRudi BeyaertWA JACOBWalther Fiers

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of an exogenous tumor-necrosis-factor (TNF) gene in TNF-sensitive cell-lines confers resistance to TNF-mediated cell-lysis.

Bart VanhaesebroeckEls DecosterXaveer VAN OSTADES VANBLADELAnne LenaertsFrans Van RoyWalther Fiers

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Tumor necrosis factor : mechanism of action and its potential for anticancer therapy

W HersRudi BeyaertPeter BrouckaertEls DecosterDirk De ValckB EveraerdtJohan GrootenAnne LenaertsClaude LibertK Schulze-Osthoff et al.

Tumor-necrosis-factor : mechanism of action at the molecular, cellular and in vivo level

Walther FiersRudi BeyaertPeter BrouckaertEls DecosterDirk De ValckBart EveraerdtJohan GrootenAnne LenaertsClaude LibertK. Schulzeosthoff et al.

1990

Onderzoek naar de mechanismen van cytokine-gemedieerde anti-tumorale aktiviteit

Bart VanhaesebroeckWalther Fiers

Tumor-necrosis-factor : mechanism of action at the molecular, cellular and in vivo level

Walther FiersRudi BeyaertPeter BrouckaertBart EveraerdtJohan GrootenAnne LenaertsClaude LibertP. SuffysNozomi TakahashiJan Tavernier et al.

A1 Journal Article in SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION