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Researcher
Ashish Kumar
Profile
Projects
Publications
Activities
Awards & Distinctions
45
Results
2023
Identification of continuous twin-screw melt granulation mechanisms for different screw configurations, process settings and formulation
Shana Van de Steene
Jeroen Van Renterghem
Valérie Vanhoorne
Chris Vervaet
Ashish Kumar
Thomas De Beer
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2023
Linking material properties to 1D-PBM parameters towards a generic model for twin-screw wet granulation
Ana Alejandra Barrera Jiménez
Kensaku Matsunami
Daan Van Hauwermeiren
Michiel Peeters
Fanny Stauffer
Eduardo dos Santos Schultz
Ashish Kumar
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
CHEMICAL ENGINEERING RESEARCH & DESIGN
2023
Partial least squares regression to calculate population balance model parameters from material properties in continuous twin-screw wet granulation
Ana Alejandra Barrera Jiménez
Kensaku Matsunami
Daan Van Hauwermeiren
Michiel Peeters
Fanny Stauffer
Eduardo dos Santos Schultz
Ashish Kumar
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2023
2022
Advances in twin-screw granulation
Valérie Vanhoorne
Ashish Kumar
Editorial material
2022
Finite element modeling of powder compaction : mini-tablets in comparison with conventionally sized tablets
Luz Naranjo Gómez
Thomas De Beer
Ashish Kumar
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2022
2021
Development and application of a mechanistic cooling and freezing model of the spin freezing step within the framework of continuous freeze-drying
Gust Nuytten
Susan Ríos Revatta
Pieter-Jan Van Bockstal
Ashish Kumar
Joris Lammens
Laurens Leys
Brecht Vanbillemont
Jos Corver
Chris Vervaet
Thomas De Beer
A1
Journal Article
in
PHARMACEUTICS
2021
Particle-scale modeling to understand liquid distribution in twin-screw wet granulation
Ashish Kumar
Stefan Radl
Krist V. Gernaey
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
PHARMACEUTICS
2021
2020
Characterization of simultaneous evolution of size and composition distributions using generalized aggregation population balance equation
Mehakpreet Singh
Ashish Kumar
Saeed Shirazian
Vivek Ranade
Gavin Walker
A1
Journal Article
in
PHARMACEUTICS
2020
Prediction of tablet weight variability in continuous manufacturing
Sonia M. Razavi
James Scicolone
Ronald D. Snee
Ashish Kumar
Johny Bertels
Philippe Cappuyns
Ivo Van Assche
Alberto M. Cuitiño
Fernando Muzzio
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2020
Why is batch processing still dominating the biologics landscape? Towards an integrated continuous bioprocessing alternative
Ashish Kumar
Isuru A. Udugama
Carina L. Gargalo
Krist V. Gernaey
A1
Journal Article
in
PROCESSES
2020
2019
Evaluation of an in-line NIR spectroscopic method for the determination of the residence time in a tablet press
Fien De Leersnyder
Valérie Vanhoorne
Ashish Kumar
Chris Vervaet
Thomas De Beer
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2019
Impact of material properties and process variables on the residence time distribution in twin screw feeding equipment
Bernd Van Snick
Ashish Kumar
Maxim Verstraeten
Kenny Pandelaere
Jens Dhondt
G Di Pretoro
Thomas De Beer
Chris Vervaet
Valérie Vanhoorne
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2019
Model-based approach to the design of pharmaceutical roller-compaction processes
Peter Toson
Diogo G. Lopes
Raphael Paus
Ashish Kumar
Jeroen Geens
Sandy Stibale
Julian Quodbach
Peter Kleinebudde
Wen-Kai Hsiao
Johannes Khinast
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS-X
2019
2017
Continuous direct compression as manufacturing platform for sustained release tablets
Bernd Van Snick
J. Holman
C. Cunningham
Ashish Kumar
Jurgen Vercruysse
Thomas De Beer
Jean Paul Remon
Chris Vervaet
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2017
Development of a continuous direct compression platform for low-dose drug products
Bernd Van Snick
J. Holman
Valérie Vanhoorne
Ashish Kumar
Thomas De Beer
Jean Paul Remon
Chris Vervaet
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2017
Twin-screw granulation process development: present approaches, understanding and needs
Ashish Kumar
K.V. Gernaey
Ingmar Nopens
Thomas De Beer
Bookchapter
in
Continuous manufacturing of pharmaceuticals
2017
Visualization of compaction behavior of pharmaceutical powders in solid-dosage manufacturing using finite element analysis
Ashish Kumar
Jens Dhondt
Jhony Bertels
Didier Klingeleers
Krist V Gernaey
Ingmar Nopens
Thomas De Beer
C3
Conference
2017
2016
Characterization of compaction behaviour of powders in solid-dosage manufacturing using finite element analysis
Ashish Kumar
Jens Dhondt
Johny Bertels
Didier Klingeleers
Krist V Gernaey
Ingmar Nopens
Thomas De Beer
C3
Conference
2016
Development of a process map : a step towards a regime map for steady-state high shear wet twin screw granulation
Ashish Kumar
Jens Dhondt
Jurgen Vercruysse
Fien De Leersnyder
Valérie Vanhoorne
Chris Vervaet
Jean Paul Remon
Krist V. Gernaey
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
POWDER TECHNOLOGY
2016
Linking granulation performance with residence time and granulation liquid distributions in twin-screw granulation : an experimental investigation
Ashish Kumar
Maija Alakarjula
Valérie Vanhoorne
Maunu Toiviainen
Fien De Leersnyder
Jurgen Vercruysse
Mikko Juuti
Jarkko Ketolainen
Chris Vervaet
Jean Paul Remon
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
2016
Methodology and pitfalls when calibrating a PBM : the case of twin-screw wet granulation
Daan Van Hauwermeiren
Thomas De Beer
Michael Ghijs
Maxim Verstraeten
Ashish Kumar
Krist V Gernaey
Kai Lee
Mary T am Ende
Pankaj Doshi
Ingmar Nopens
C3
Conference
2016
Model-based analysis of a twin-screw wet granulation system for continuous solid dosage manufacturing
Ashish Kumar
Jurgen Vercruysse
Séverine Mortier
Chris Vervaet
Jean Paul Remon
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
COMPUTERS & CHEMICAL ENGINEERING
2016
2015
Analysis of a twin-screw granulation process using a combined experimental and computational approach
Ashish Kumar
Jurgen Vercruysse
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2015
Combined experimental and computational approach to elucidate the twin-screw granulation process
Ashish Kumar
Jurgen Vercruysse
Chris Vervaet
Jean Paul Remon
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2015
Conceptual framework for model-based analysis of residence time distribution in twin-screw granulation
Ashish Kumar
Jurgen Vercruysse
Valérie Vanhoorne
Maunu Toiviainen
Pierre-Emmanuel Panouillot
Mikko Juuti
Chris Vervaet
Jean Paul Remon
Krist V Gernaey
Thomas De Beer
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
2015
Detailed simulation of particle and liquid distribution in the mixing zone of a TwinScrew granulator
Ashish Kumar
Stefan Radl
Johannes G Khinast
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2015
Development of regime map for steady-state high shear wet twin-screw granulation
Ashish Kumar
Jens Dhondt
Jurgen Vercruysse
Fien De Leersnyder
Valérie Vanhoorne
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2015
Evaluation of an in-line particle imaging tool for monitoring twin-screw granulation performance
Ashish Kumar
Jens Dhondt
Fien De Leersnyder
Jurgen Vercruysse
Valérie Vanhoorne
Chris Vervaet
Jean Paul Remon
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
POWDER TECHNOLOGY
2015
Experimental and model-based analysis of twin-screw wet granulation in pharmaceutical processes
Ashish Kumar
Ingmar Nopens
Thomas De Beer
Krist V Gernaey
Dissertation
2015
Experimental investigation linking granulation performance with Residence time and granulation liquid distributions in TwinScrew granulation
Ashish Kumar
Maija Alkarjula
Valérie Vanhoorne
Maunu Toiviainen
Mikko Juuti
Chris Vervaet
Jarkko Ketolainen
Krist V Gernaey
Ingmar Nopens
Thomas De Beer
C3
Conference
2015
Experimental investigation of residence time, granulation liquid and granule size distributions in twin-screw granulation
Ashish Kumar
Maija Alakarjula
Valérie Vanhoorne
Maunu Toiviainen
Mikko Juuti
Chris Vervaet
Jarkko Ketolainen
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2015
Experimental investigation of the link between granulation performance, residence time and granulation liquid distribution in twin-screw granulation
Ashish Kumar
Maija Alakarjula
Valérie Vanhoorne
Maunu Toiviainen
Mikko Juuti
Chris Vervaet
Jarkko Ketolainen
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2015
Investigation of twin screw granulation : integrating experimental and computational approaches
Ashish Kumar
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2015
Model-based characterisation of twin-screw granulation system for continuous solid dosage manufacturing
Ashish Kumar
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
P1
Conference
2015
2014
Development of a population balance model for continuous twin-screw granulation in pharmaceutical manufacturing
Ashish Kumar
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2014
Experimental and model-based investigation of twin screw granulation: towards more profound process knowledge
Ashish Kumar
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2014
Experimental investigation of granule shape and size dynamics in twin-screw granulation
Ashish Kumar
Jurgen Vercruysse
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2014
Experimental investigation of granule size and shape dynamics in twin-screw granulation
Ashish Kumar
Jurgen Vercruysse
Giacomo Bellandi
Krist V Gernaey
Chris Vervaet
Jean Paul Remon
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2014
Experimental investigation of residence time distribution in twin-screw granulation
Ashish Kumar
Jurgen Vercruysse
Maunu Toiviainen
Pierre-Emmanuel Panouillot
Mikko Juuti
Valérie Vanhoorne
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2014
Mixing and transport during pharmaceutical twin-screw wet granulation : experimental analysis via chemical imaging
Ashish Kumar
Jurgen Vercruysse
Maunu Toiviainen
Pierre-Emmanuel Panouillot
Mikko Juuti
Valérie Vanhoorne
Chris Vervaet
Jean Paul Remon
Krist V Gernaey
Thomas De Beer
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2014
Model-based analysis and experimental validation of residence time distribution in twin-screw granulation
Ashish Kumar
Jurgen Vercruysse
Maunu Toiviainen
Pierre-Emmanuel Panouillot
Mikko Juuti
Valérie Vanhoorne
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2014
2013
An experimental study on effect of screw configuration in twin screw wet granulation
Ashish Kumar
Jurgen Vercruysse
Krist V Gernaey
Ingmar Nopens
Thomas De Beer
C3
Conference
2013
Evaluation of particle shape and size evolution during high-shear wet granulatoin using twin-screw granulator
Ashish Kumar
Jurgen Vercruysse
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2013
Model-based analysis of high shear wet granulation from batch to continuous processes in pharmaceutical production: a critical review
Ashish Kumar
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2013
One dimensional model of the prediction of residence time distribution granulation in a twin-screw granulator
Ashish Kumar
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2013