Research Explorer

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Researcher

Arne Heyerick

Awards & Distinctions

81 Results

2015

8-prenylnaringenin and tamoxifen inhibit the shedding of irradiated epithelial cells and increase the latency period of radiation-induced oral mucositis

Tine De RyckAnnouchka Van ImpeBarbara VanhoeckeArne HeyerickLuc VakaetWilfried De NeveDoreen MüllerMargret SchmidtWolfgang DörrMarc Bracke

A1 Journal Article in STRAHLENTHERAPIE UND ONKOLOGIE

Novel anti-inflammatory daucane esters from Laserpitium zernyi Hayek (Apiaceae)

Visnja PopovicJan GoemanNadia BougarneArne HeyerickKarolien De BosscherJohan Van der Eycken

Twelve-month consumption of a polyphenol extract from olive (Olea europaea) in a double blind, randomized trial increases serum total osteocalcin levels and improves serum lipid profiles in postmenopausal women with osteopenia

R FilipSam PossemiersArne HeyerickI PinheiroG RaszewskiMJ DaviccoV Coxam

A1 Journal Article in JOURNAL OF NUTRITION HEALTH & AGING

2014

An immunogen synthesis strategy for the development of specific anti-deoxynivalenol monoclonal antibodies

Melanie SandersYirong GuoAbhishek IyerYara Ruiz GarciaAnastasia GalvitaArne HeyerickDieter DeforceMartijn RisseeuwSerge Van CalenberghMarc Bracke et al.

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

Feeding soybean meal increases the blood level of isoflavones and reduces the steroidogenic capacity in bovine corpora lutea, without affecting peripheral progesterone concentrations

Steven CoolsWim Van Den BroeckLynn VanhaeckeArne HeyerickPhilippe BossaertMiel HostensGeert Opsomer

A1 Journal Article in ANIMAL REPRODUCTION SCIENCE

Heterologous screening of hybridomas for the development of broad-specific monoclonal antibodies against deoxynivalenol and its analogues

Yirong GuoMelanie SandersAnastasia GalvitaArne HeyerickDieter DeforceMarc BrackeS EreminSarah De Saeger

A1 Journal Article in WORLD MYCOTOXIN JOURNAL

In vitro inhibition of the transcription factor NF-κB and cyclooxygenase by bamboo extracts

Laura Van HoyweghenKarolien De BosscherGuy HaegemanDieter DeforceArne Heyerick

A1 Journal Article in PHYTOTHERAPY RESEARCH

Sesquiterpenes from selected Laserpitium L. species as antimicrobial agents

Visnja PopovicDejan StojkovicMilos NikolicNadia BougarneJan GoemanArne HeyerickKarolien De BosscherMarina SokovicJohan Van der Eycken

2013

Consumption of an olive polyphenolic extract for 12 months prevents bone loss and improves serum lipid profiles in postmenopausal women

Véronique CoxamSam PossemiersArne HeyerickGrzegorz RaszewskiMarie-Jeanne DaviccoFilip Rafal

Cytotoxic activity of Laserpitium latifolium L. extract and its daucane and phenylpropanoid constituents

Višnja PopovićArne HeyerickSilvana PetrovićSerge Van CalenberghIzet KaralicMarjan NiketićDieter Deforce

A1 Journal Article in RECORDS OF NATURAL PRODUCTS

Metabolism of hop-derived bitter acids

Ko CattoorMichael DreselLies De BockKoen BousseryJan Van BocxlaerJean Paul RemonDenis De KeukeleireDieter DeforceThomas HofmannArne Heyerick

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Sesquiterpene lactones from the extracts of two Balkan endemic Laserpitium species and their cytotoxic activity

Visnja PopovicArne HeyerickSilvana PetrovićSerge Van CalenberghIzet KaralićMarjan NiketićDieter Deforce

A1 Journal Article in PHYTOCHEMISTRY

2012

Absorption, translocation and metabolism of metamitron in Chenopodium album

Jonas AperEls MechantBaruch RubinArne HeyerickGert CallebautSven MangelinckxDieter DeforceNorbert De KimpeRobert BulckeDirk Reheul

A1 Journal Article in PEST MANAGEMENT SCIENCE

Phenolic compounds and anti-oxidant capacity of twelve morphologically heterogeneous bamboo species

Laura Van HoyweghenThomas De BeerDieter DeforceArne Heyerick

A1 Journal Article in PHYTOCHEMICAL ANALYSIS

Prenylated chalcone xanthohumol associates with histones in breast cancer cells: a novel target identified by a monoclonal antibody

Ciska WynsKatleen Van SteendamBarbara VanhoeckeDieter DeforceMarc BrackeArne Heyerick

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

2011

Bioavailability of hop-derived iso-α-acids and reduced derivatives

Ko CattoorJean Paul RemonKoen BousseryJan Van BocxlaerMarc BrackeDenis De KeukeleireDieter DeforceArne Heyerick

A1 Journal Article in FOOD & FUNCTION

Production of monoclonal antibodies against hop-derived (Humulus lupulus L.) prenylflavonoids and the development of immunoassays

Ciska WynsLara DeryckeBram SoenenSelin BolcaDieter DeforceMarc BrackeArne Heyerick

A1 Journal Article in TALANTA

The intestinal microbiome: a separate organ inside the body with the metabolic potential to influence the bioactivity of botanicals

Sam PossemiersSelin BolcaWilly VerstraeteArne Heyerick

A1 Journal Article in FITOTERAPIA

2010

A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts

R ErkkolaS VervarckeStijn VansteelandtP RompottiDenis De KeukeleireArne Heyerick

A1 Journal Article in PHYTOMEDICINE

Antioxidant flavone glycosides from the leaves of Fargesia robusta

Laura Van HoyweghenIzet KaralicSerge Van CalenberghDieter DeforceArne Heyerick

A1 Journal Article in JOURNAL OF NATURAL PRODUCTS

Cloning and molecular analysis of HlbZip1 and HlbZip2 transcription factors putatively involved in the regulation of the lupulin metabolome in hop (Humulus lupulus L.)

Jaroslav MatouśekTomáś KocábekJosef PatzakJan StehlikZoltan FůssyKarel KroftaArne HeyerickIsabel Roldán-RuizLina MaloukhDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Development of a high-throughput LC/APCI-MS method for the determination of thirteen phytoestrogens including gut microbial metabolites in human urine and serum

Ciska WynsSelin BolcaDenis De KeukeleireArne Heyerick

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Disposition of hop prenylflavonoids in human breast tissue

Selin BolcaJinghu LiDejan NikolicNathalie RochePhillip BlondeelSam PossemiersDenis De KeukeleireMarc BrackeArne HeyerickRichard B Van Breemen et al.

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

Disposition of soy isoflavones in normal human breast tissue

Selin BolcaMireia Urpi-SardaPhillip BlondeelNathalie RocheLynn VanhaeckeSam PossemiersNawaf Al-MaharikNigel BottingDenis De KeukeleireMarc Bracke et al.

A1 Journal Article in AMERICAN JOURNAL OF CLINICAL NUTRITION

Radical scavenging capacity of hop-derived products

Laura Van HoyweghenMartin BiendlArne Heyerick

A2 Journal Article in BREWING SCIENCE

Transport of hop bitter acids across intestinal Caco-2 cell monolayers

Ko CattoorMarc BrackeDieter DeforceDenis De KeukeleireArne Heyerick

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

2009

A prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts

Alvin IbarraSophie LafayArne HeyerickStefaan VervarckeHerman Depyperemarc brackeDenis De Keukeleire

Cloning and molecular analyses of hop transcription factors

Jaroslav MatoušekThomas KocábekJosef ŠkopekL OrctováJ StehlikZoltan FüssyJosef PatzakKarel KroftaLina MaloukhIsabel Roldán-Ruiz et al.

Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17beta-estradiol equivalents

Selin BolcaCiska WynsSam PossemiersHerman DepypereDenis De KeukeleireMarc BrackeWilly VerstraeteArne Heyerick

A1 Journal Article in JOURNAL OF NUTRITION

Hop (Humulus lupulus)-Derived Bitter Acids as Multipotent Bioactive Compounds

Marjan Van CleemputKo CattoorKarolien De BosscherGuy HaegemanDenis De KeukeleireArne Heyerick

A1 Journal Article in Journal of Natural Products

Hop bitter acids efficiently block inflammation independent of GRα, PPARα, or PPARγ

Marjan Van CleemputArne HeyerickClaude LibertKatrien SwertsJan PhilippéDenis De KeukeleireGuy HaegemanKarolien De Bosscher

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

Identification of full-length cDNA sequences of hop (Humulus lupulus L.) candidate genes of the prenylflavonid pathway

Lina MaloukhJelle De KeukeleireJaroslav MatousekPaul D MatthewsAxel SchwekendiekArne HeyerickDenis De KeukeleireErik Van BockstaeleIsabel Roldán-Ruiz

Microbial activation of mixtures of isoflavones, prenylflavonoids and lignans

Selin BolcaEllen EeckhautArne HeyerickDenis De KeukeleireHerman DepypereMarc BrackeTom Van de WieleWilly Verstraete

Microbial and dietary factors associated with the Equol and 8-prenylnaringenin producer phenotypes

Selin BolcaSam PossemiersWilly VerstraeteTom Van de WieleArne HeyerickDenis De KeukeleireInge HuybrechtsStefaan De HenauwHerman DepypereMarc Bracke

2008

Cellular uptake of soy-derived phytoestrogens in vitro and in human whole blood

Julie Maubachmarc brackeHerman DepypereDenis De KeukeleireArne Heyerick

A2 Journal Article in Journal of Pre-Clinical and Clinical Research

Development of a high-throughput LC-APCI-MS method for the determination of 13 phytoestrogens (including gut microbial metabolites) in human urine and serum

Ciska WynsSelin BolcaDenis De KeukeleireArne Heyerick

Eubacterium limosum activates isoxanthohumol from hops (Humulus lupulus L.) into the potent phytoestrogen 8-prenylnaringenin in vitro and in rat intestine

Sam PossemiersSylvie RABOTJuan carlos ESPINAurelia BRUNEAUCatherine PHILIPPEAntonio GONZALEZ-SARRIASArne HeyerickFrancisco TOMAS-BARBERANDenis De KeukeleireWilly Verstraete

A1 Journal Article in JOURNAL OF NUTRITION

In-vitro and in-vivo evidence for the anti-inflammatory activity of hop bitter acids in mouse

Marjan Van CleemputArne HeyerickClaude LibertDenis De KeukeleireGuy HaegemanKarolien De Bosscher

Plant polyphenolics as anti-invasive cancer agents

Marc BrackeBarbara VanhoeckeLara DeryckeSelin BolcaSam PossemiersArne HeyerickChristian StevensDenis De KeukeleireHerman DepypereWilly Verstraete et al.

A1 Journal Article in ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY

2007

Constitutive expression of a grapevine stilbene synthase gene in transgenic hop (Humulus lupulus L.) yields resveratrol and its derivatives in substantial quantities

A SCHWEKENDIEKO SPRINGArne HeyerickB PICKELNT PITSCHF PESCHKEDenis De KeukeleireG WEBER

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

HIMyb3, a putative regulatory factor in hop (Humulus lupulus L.), shows diverse biological effects in heterologous transgenotes

J MATOUSEKT KOCABEKJ PATZAKJ SKOPEKL MALOUKHArne HeyerickZ FUSSYIsabel Roldán-RuizDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Microbial and dietary factors are associated with the equol producer phenotype in healthy postmenopausal women

Selin BolcaSam PossemiersAnnelies HerregatInge HuybrechtsArne HeyerickStephanie De VrieseMarian VerbruggenHerman DepypereDenis De KeukeleireMarc Bracke et al.

A1 Journal Article in JOURNAL OF NUTRITION

Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women

Selin BolcaSam PossemiersVeerle MaervoetInge HuybrechtsArne HeyerickStefaan VervaeckeHerman DepypereDenis De KeukeleireMarc BrackeStefaan De Henauw et al.

A1 Journal Article in BRITISH JOURNAL OF NUTRITION

Microbial and dietary factors associated with the equaol and 8-prenylnaringenin poducer phenotypes

Selin BolcaSam PossemiersArne HeyerickInge HuybrechtsHerman DepypereDenis De KeukeleireMarc BrackeStefaan De HenauwWilly VerstraeteTom Van de Wiele

Relevance of organic farming and effect of climatological conditions on the formation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol in hop (Humulus lupulus L.)

Jelle De KeukeleireI JANSSENSArne HeyerickG GHEKIEREJ CAMBIEIsabel Roldán-RuizErik Van BockstaeleDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Resveratrol in beer to increase life span of brewing yeast under stressed conditions

Anita Van LandschootDana VanderputtenLeen De GelderArne Heyerick

Withaferin A strongly elicits I kappa B kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity

Mary KailehWim Vanden BergheArne HeyerickJ HORIONJ PIETTEClaude LibertDenis De KeukeleireT ESSAWIGuy Haegeman

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2006

A first prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts

Arne HeyerickS VERVARCKEHerman Depyperemarc brackeDenis De Keukeleire

A1 Journal Article in MATURITAS

ARE PHYTOESTROGENS OF ANY HELP

Herman DepypereMarc BrackeBarbara VanhoeckeDenis De KeukeleireArne HeyerickSelin BolcaWilly Verstraete

Anti-proliferative properties of prenylated flavonoids from hops (Humulus lupulus L.) in human prostate cancer cell lines

L DELMULLEA BELLAHCENEW DHOOGEFrank ComhaireF ROELENSK HUVAEREArne HeyerickV CASTRONOVODenis De Keukeleire

A1 Journal Article in PHYTOMEDICINE

Bioavailability of phytoestrogens from soy and hops

Selin BolcaSam PossemiersArne HeyerickDenis De KeukeleireHerman DepypereMarc BrackeInge HuybrechtsStefaan De HenauwWilly Verstraete

Efficient extraction of High-Quality total RNA from various hop tissues (Humulus lupulus L.)

Jelle De KeukeleireIsabel Roldán-RuizErik Van BockstaeleArne HeyerickDenis De Keukeleire

A1 Journal Article in PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

Exploring the 8-PN producer phenotype: an intervention trial with 50 healthy post-menopausal Caucasian women

Selin BolcaSam PossemiersVeerle MaervoetArne HeyerickDenis De KeukeleireHerman DepypereMarc BrackeInge HuybrechtsTom Van de WieleWilly Verstraete

Exploring the equol producer phenotype: an intervention trial with 100 healthy post-menoapausal Caucasian women

Selin BolcaSam PossemiersAnnelies HerregatArne HeyerickDenis De KeukeleireHerman DepypereMarc BrackeInge HuybrechtsStefaan De HenauwTom Van de Wiele et al.

Metabolism of the food-associated carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine by human intestinal microbiota

Lynn VanhaeckeNathalie Van HoofW VAN BRABANDTBram SoenenArne HeyerickNorbert De KimpeDenis De KeukeleireWilly VerstraeteTom Van de Wiele

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Sequence analysis of a "true" chalcone synthase (chs_H1) oligofamily from hop (Humulus lupulus L.) and PAP1 activation of chs_H1 in heterologous systems

J MATOUSEKL VRBAJ SKOPEKL ORCTOVAK PESINAArne HeyerickD BAULCOMBEDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The hop phytoestrogen, 8-prenylnaringenin, reverses the ovariectomy-induced rise in skin temperature in an animal model of menopausal hot flushes

J BOWEXF LIJ KINSEY-JONESArne HeyerickS BRAINS MILLIGANK O'BYRNE

A1 Journal Article in JOURNAL OF ENDOCRINOLOGY

The prenylflavonoid isoxanthohumol from hops (Humulus lupulus L.) is activated into the potent phytoestrogen 8-prenylnaringenin in vitro and in the human intestine

Sam PossemiersSelin BolcaCharlotte GrootaertArne HeyerickKarel DecroosWillem DhoogeDenis De KeukeleireS RABOTWilly VerstraeteTom Van de Wiele

A1 Journal Article in JOURNAL OF NUTRITION

2005

A safety study of oral tangeretin and xanthohumol administration to laboratory mice

Barbara VanhoeckeFEMKE DELPORTEEva Van BraeckelArne HeyerickHerman DepypereM NUYTINCKDenis De Keukeleiremarc bracke

A1 Journal Article in IN VIVO

Activation of proestrogens from hops (Humulus lupulus L.) by intestinal microbiota; Conversion of isoxanthohumol into 8-prenylnaringenin

Sam PossemiersArne HeyerickVeerle RobbensDenis De KeukeleireWilly Verstraete

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cloning and molecular analysis of the regulatory factor HiMyb1 in hop (Humulus lupulus L.) and the potential of hop to produce bioactive prenylated flavonoids

J MATOUSEKL VRBAP NOVAKJ PATZAKJelle De KeukeleireJ SKOPEKArne HeyerickIsabel Roldán-RuizDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Fate of flavins in sensitized photodegradation of isohumulones and reduced derivatives: studies on formation of radicals via EPR combined with detailed product analyses

Arne HeyerickKevin HuvaereDenis De KeukeleireMDE FORBES

A1 Journal Article in PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Photooxidative degradation of beer bittering principles: A key step on the route to lightstruck flavor formation in beer

Kevin HuvaereML ANDERSENLH SKIBSTEDArne HeyerickDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Prenylflavonoids account for intriguing biological activities of hops

Denis De KeukeleireArne Heyerick

Screening for genes involved in the biosynthesis of prenylated chalcones in hops (Humulus lupulus L.).

Jelle De KeukeleireIsabel Roldán-RuizErik Van BockstaeleArne HeyerickDenis De Keukeleire

2004

Distribution of soy-derived phytoestrogens in human breast tissue and biological fluids

J MAUBACHHerman DepypereJan GoemanJohan Van der EyckenArne Heyerickmarc brackePhillip BlondeelDenis De Keukeleire

A1 Journal Article in OBSTETRICS AND GYNECOLOGY

Riboflavin-sensitized photooxidation of isohumulones and derivatives

Kevin HuvaereK OLSENML ANDERSENLH SKIBSTEDArne HeyerickDenis De Keukeleire

A1 Journal Article in PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

2003

3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase

Veerle VanheusdenHélène Munier-LehmannMatheus FroeyenLaurence DuguéArne HeyerickDenis De KeukeleireSylvie PochetRoger BussonPiet HerdewijnSerge Van Calenbergh

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Formation and accumulation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol during flowering of hops (Humulus lupulus L.)

Jelle De KeukeleireG OOMSArne HeyerickIsabel Roldán-RuizErik Van BockstaeleDenis De Keukeleire

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Photolysis of hop-derived trans-iso-alpha-acids and trans-tetrahydroiso-alpha-acids: product identification in relation to the lightstruck flavour of beer

Arne HeyerickYN ZHAOPatrick SandraKevin HuvaereFrederik RoelensDenis De Keukeleire

A1 Journal Article in PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Quantitation of soy-derived phytoestrogens in human breast tissue and biological fluids by high-performance liquid chromatography

J MAUBACHmarc brackeArne HeyerickHerman DepypereRudolphe SerreynMarcus MareelDenis De Keukeleire

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Radicaloid-type oxidative decomposition of beer bittering agents revealed

Kevin HuvaereML ANDERSENK OLSENLH SKIBSTEDArne HeyerickDenis De Keukeleire

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

2002

Modulation of the phytoestrogenicity of beer by monoterpene alcohols present in various hop oil fractions

Arne HeyerickDenis De KeukeleireCarlos Van PeteghemSarah De Saeger

A1 Journal Article in JOURNAL OF THE INSTITUTE OF BREWING

Oestrogenic activity of the hop phyto-oestrogen, 8-prenylnaringenin.

S MILLIGANJ KALITAV POCOCKArne HeyerickL DE COOMANHaojing RongDenis De Keukeleire

A1 Journal Article in REPRODUCTION

2001

Mechanism for the lightstruck flavor in beer revealed by time-resolved electron paramagnetic resonance.

CS BURNSArne HeyerickDenis De KeukeleireMDE FORBES

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

Prenylated hop flavonoids are key agents in relation to health-beneficial properties of beer

Denis De KeukeleireSR MILLIGANJC KALITAV POCOCKL DE COOMANArne HeyerickHaojing Rong

Unraveling the mechanism of the lightstruck flavor of beer

Arne HeyerickDenis De Keukeleire

2000

Functional properties of hop polyphenols

Denis De KeukeleireLuc De CoomanHJ RONGArne HeyerickJ KALITASR MILLIGAN

1999

Identification of a potent phytoestrogen in hops (Humulus lupulus L.) and beer.

SR MILLIGANJC KALITAArne HeyerickHaojing RongL DE COOMANDenis De Keukeleire

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM

1997

Hop-derived phytoestrogens in beer?

Denis De KeukeleireLuc De CoomanArne HeyerickSR MILLIGAN

The oestrogen ic activity of hops (Humulus lupulus L.) revisited

Denis De KeukeleireSR MILLIGANLuc De CoomanArne Heyerick

A4 Journal Article in Pharm. Pharmacol. Lett., 7e jg