Research Explorer

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Researcher

Anton De Spiegeleer

Publications & Research Data

Awards & Distinctions

48 Results

2026

Navigating in the chemical space of peptides : computational strategies and molecular features to unveil their functional and drug-like properties

Ewerton Cristhian Lima de OliveiraJuliana Auzier Seixas FeioGabriel Pereira CoelhoLidiane Diniz Do NascimentoAnderson Henrique LimaCaio Marcos Flexa RodriguesAnton De SpiegeleerEvelien WynendaeleClaudomiro SalesBart De Spiegeleer et al.

A1 Journal Article in PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Potentially clinically significant drug-drug interactions in older adults with atrial fibrillation and multimorbidity : prevalence, correlates, and association with adverse clinical outcomes in a Swedish national register-based study

Cheïma AmrouchDavide Liborio VetranoDirk De BacquerNicola FerriIne SimalCecilia DamianoLu DaiAmaia Calderón-LarrañagaAstrid BrysAnton De Spiegeleer et al.

A1 Journal Article in CARDIOVASCULAR DRUGS AND THERAPY

Quorum sensing peptides in sarcopenia : insights from iAM373

Liesbeth Crombezsumaira jabeenPetar NaumovskiNele Van Den NoortgateBart De SpiegeleerEvelien WynendaeleAnton De Spiegeleer

Single- and dual-task gait assessment before and after cerebrospinal fluid drainage in suspected idiopathic normal pressure hydrocephalus: Dual-task walking identifies additional responders

Celine SuckerJan-Philipp LeibfarthMichelle RyanAaron HaslbauerAnton De SpiegeleerEthan TaubReto W. KressigRoland Rössler

U Journal Article in GAIT & POSTURE

The association between statins and gait speed reserve in older adults : effects of concomitant medication

Anton De SpiegeleerAntoon BronselaerIne MahieuDorien VreysAaron HaslbauerJan-Philipp LeibfarthLara Van SchooteAster Wakjira GaredoMirko PetrovicEvelien Wynendaele et al.

A1 Artikel in een tijdschrift in GEROSCIENCE

2025

Beyond molecular weight : peptide characteristics influencing the sensitivity of retention to changes in organic solvent in reversed-phase chromatography

Amélie DescampsHannah HirmzEwerton de OliveiraAnton De SpiegeleerJuliana FeioKaue da CostaBart De SpiegeleerEvelien Wynendaele

A1 Artikel in een tijdschrift in ACS OMEGA

Efficacy of the power centering for seniors intervention on physical functional performance in older community-dwelling adults : a secondary analysis of a randomised controlled trial

Roland RösslerMathias BirrerAaron HaslbauerJay GoldfarbAnton De SpiegeleerIrene HärdiReto W. Kressig

A1 Artikel in een tijdschrift in SCIENTIFIC REPORTS

Evaluating an integrated clinical pharmacist model in a geriatric day hospital : a prospective single-centre observational study

Ine SimalAndreas CapiauAnton De SpiegeleerAnja VelgheNele Van Den NoortgateMirko PetrovicAnnemie Somers

A1 Artikel in een tijdschrift in INTERNATIONAL JOURNAL OF CLINICAL PHARMACY

Implementation of blood flow restriction training in the acute geriatric unit

Raoul De SmetAstrid BrysPatrick CaldersEvelien WynendaeleNele Van Den NoortgateAnton De Spiegeleer

A1 Artikel in een tijdschrift in AGE AND AGEING

Quorum sensing peptidomics : 'details make perfection, and perfection is not a detail'

Amélie DescampsEvelien WynendaeleAnton De Spiegeleer

Role of peptides in skeletal muscle wasting : a scoping review

Petar NaumovskiBart De SpiegeleerAster Wakjira GaredoChristophe Van De WieleVincent MoulyKatarzyna Goljanek‐WhysallKauê Santana da CostaEwerton Cristhian Lima de OliveiraEvelien WynendaeleAnton De Spiegeleer

A1 Artikel in een tijdschrift in JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE

Sample preparation in analytical peptidomics : it's all about timing

Amélie DescampsBart De SpiegeleerEvelien WynendaelePetar NaumovskiAnton De Spiegeleer

A2 Artikel in een tijdschrift in TALANTA OPEN

2024

Geriatricians-on-the-Move for sustainable ageing

Anton De SpiegeleerBart De Spiegeleer

Redactioneel materiaal

Prostate-specific membrane antigen biology and pathophysiology in prostate carcinoma, an update : potential implications for targeted imaging and therapy

Justine MaesSimon GesquièreAnton De SpiegeleerAlex MaesChristophe Van De Wiele

A1 Artikel in een tijdschrift in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Streptococcal quorum sensing peptide CSP-7 contributes to muscle inflammation and wasting

Anton De SpiegeleerAmélie DescampsEvelien WynendaelePetar NaumovskiLiesbeth CrombezMarta PlanasLidia FeliuDaniel KnappeVincent MoulyAnne Bigot et al.

A1 Artikel in een tijdschrift in BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The conceptual definition of sarcopenia : Delphi consensus from the Global Leadership Initiative in Sarcopenia (GLIS)

Ben KirkPeggy M. CawthonHidenori AraiJose A. Avila-FunesRocco BarazzoniShalender BhasinEllen F. BinderOlivier BruyereTommy CederholmLiang-Kung Chen et al.

A1 Artikel in een tijdschrift in AGE AND AGEING

The role of the quorum sensing peptide PlnA in the gut microbiome-sarcopenia axis

Amélie DescampsAnton De SpiegeleerLiesbeth CrombezMorten KjosEvelien Wynendaele

The Saliva and Muscle Study (SaMu) : rationale and protocol for associations between salivary microbiome and accelerated muscle ageing

Liesbeth CrombezAmélie DescampsHannah HirmzMartijn LambertJonas CalewaertD. SilukM. MarkuszewskiM. BiesemansG. PetrellaD. Cicero et al.

A2 Artikel in een tijdschrift in JOURNAL OF FRAILTY & AGING

2023

Bacterial quorum-sensing peptides as immune modulators present in systemic circulation

Anton De SpiegeleerAmélie DescampsSrinath GovindarajanJulie CoudenysKevin Van der borghtHannah HirmzNele Van Den NoortgateDirk ElewautBart De SpiegeleerEvelien Wynendaele

A1 Artikel in een tijdschrift in BIOMOLECULES

Peptidomics : LC-MS operational parameters do matter

Amélie DescampsKevin Van der borghtAnton De SpiegeleerEvelien WynendaeleBart De Spiegeleer

A1 Artikel in een tijdschrift in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Potential role of statins in treatment of acute sarcopenia

Anton De SpiegeleerHasan KahyaLiesbeth CrombezAmélie DescampsRoland RösslerReto W. KressigBruno LapauwEvelien WynendaeleDirk ElewautBart De Spiegeleer et al.

A1 Artikel in een tijdschrift in MEDICAL HYPOTHESES

2022

A fit-for-purpose LC-MS/MS method for the analysis of selected Streptococcal quorum sensing peptides in human saliva

Frederick VerbekeKevin Van der borghtAnton De SpiegeleerNathan DebunneYorick JanssensEvelien WynendaeleBart De Spiegeleer

A1 Artikel in een tijdschrift in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Lebensmittelverfügbarkeit als Risikofaktor für die Prävalenz von Sarkopenie in der Akutgeriatrie : Sarcopenia EAMA 9+ Project

U. John-KoehlerH. SchmidG. DeckerU. BraischD. Sanchez-RodriguezS. HopeK. PiotrowiczJ. GasowskiM. SurquinE. Marco et al.

Sarcopenia : a gut-feeling for quorum sensing peptides and natural killer T cells

Anton De SpiegeleerNele Van Den NoortgateDirk ElewautEvelien Wynendaele

Statin intake and all-cause mortality among older nursing home residents

Anton De SpiegeleerJordi Van MigerodeAntoon BronselaerEvelien WynendaeleMilan PeelmanFilip VandaeleGeert ByttebierGuy De TréLuc BelmansChristophe Van De Wiele et al.

A1 Artikel in een tijdschrift in GERONTOLOGY

The bacterial quorum sensing peptide iAM373 is a novel inducer of sarcopenia

Anton De SpiegeleerEvelien WynendaeleAmélie DescampsNathan DebunneBart BraeckmanMarjan De MeyJulie CoudenysLiesbeth CrombezFrederick VerbekeYorick Janssens et al.

A1 Artikel in een tijdschrift in CLINICAL AND TRANSLATIONAL MEDICINE

The quorum sensing peptide EntF* promotes colorectal cancer metastasis in mice : a new factor in the host-microbiome interaction

Evelien WynendaeleNathan DebunneYorick JanssensAnton De SpiegeleerFrederick VerbekeLiesa TackSophie Van WeldenEvy GoossensDaniel KnappeRalf Hoffmann et al.

A1 Artikel in een tijdschrift in BMC BIOLOGY

2021

Acute sarcopenia changes following hospitalization : influence of pre-admission care dependency level

Anton De SpiegeleerHasan KahyaDolores Sanchez-RodriguezKarolina PiotrowiczMurielle SurquinEster MarcoCeline DetremerieDhurgham HusseinSuzy HopeDhayana Dallmeier et al.

A1 Artikel in een tijdschrift in AGE AND AGEING

Hospital mortality in COVID-19 patients in Belgium treated with statins, ACE inhibitors and/or ARBs

Geert ByttebierLuc BelmansMyriam AlexanderBo E. H. SaxbergBart De SpiegeleerAnton De SpiegeleerNick DevrekerJens Van PraetKarolien VanhoveReinhilde Reybrouck et al.

A1 Artikel in een tijdschrift in HUMAN VACCINES & IMMUNOTHERAPEUTICS

Nutritional interventions to improve muscle mass, muscle strength, and physical performance in older people : an umbrella review of systematic reviews and meta-analyses

Evelien GielenDavid BeckweeAndreas DelaereSandra De BreuckerMaurits VandewoudeIvan BautmansAnton De SpiegeleerCharlotte BeaudartIngo BeyerOlivier Bruyère et al.

A1 Journal Article in NUTRITION REVIEWS

PapRIV : a BV-2 microglial cell activating quorum sensing peptide

Yorick JanssensNathan DebunneAnton De SpiegeleerEvelien WynendaeleMarta PlanasLidia FeliuAlessandra QuartaChristel ClaesDebby Van DamPeter Paul De Deyn et al.

A1 Journal Article in SCIENTIFIC REPORTS

2020

A role for iNKT cells in sarcopenia

Anton De SpiegeleerHasan KahyaNele Van Den NoortgateEvelien WynendaeleTine DecruySrinath GovindarajanDirk Elewaut

An unexpected role for iNKT cells in skeletal muscle homeostasis

Anton De SpiegeleerHasan KahyaNele Van Den NoortgateEvelien WynendaeleTine DecruySrinath GovindarajanDirk Elewaut

Influence of blood collection methods and long-term plasma storage on quorum-sensing peptide stability

Nathan DebunneAnton De SpiegeleerDorian DepuydtYorick JanssensAmélie DescampsEvelien WynendaeleBart De Spiegeleer

A1 Journal Article in ACS OMEGA

Quorum sensing molecules as a novel microbial factor impacting muscle cells

Anton De SpiegeleerDirk ElewautNele Van Den NoortgateYorick JanssensNathan DebunneSelien Van LangenhoveSrinath GovindarajanBart De SpiegeleerEvelien Wynendaele

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Quorum sensing peptides and their interactions with the host

Evelien WynendaeleNathan DebunneFrederick VerbekeYorick JanssensAnton De SpiegeleerBart De Spiegeleer

Bookchapter in Quorum sensing : microbial rules of life

The effects of ARBs, ACEis, and statins on clinical outcomes of COVID-19 infection among nursing home residents

Anton De SpiegeleerAntoon BronselaerJames T. TeoGeert ByttebierGuy De TréLuc BelmansRichard DobsonEvelien WynendaeleChristophe Van de WieleFilip Vandaele et al.

A1 Journal Article in JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION

2019

Exercise interventions for the prevention and treatment of sarcopenia : a systematic umbrella review

D. BeckweeA. DelaereS. AelbrechtV. BaertC. BeaudartO. BruyereM. De Saint-HubertIvan BautmansIngo BeyerSandra De Breucker et al.

A1 Journal Article in JOURNAL OF NUTRITION HEALTH & AGING

Sarcopenia in acute care patients : protocol for the European collaboration of geriatric surveys : Sarcopenia 9+EAMA project

Dolores Sanchez-RodriguezSuzy HopeKarolina PiotrowiczFlorence BenoitJoanna CzesakDhayana DallmeierGenia DeckerAnton De SpiegeleerAnette Hansen HojmannDana Hrnciarikova et al.

A1 Journal Article in JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION

2018

An unusual presentation of a case of human psittacosis

Yannick Vande WeygaerdeCharlot VersteeleElke ThijsAnton De SpiegeleerJerina BoelensDaisy VanrompayEva Van BraeckelKarim Vermaelen

A2 Journal Article in RESPIRATORY MEDICINE CASE REPORTS

Pharmacological interventions to improve muscle mass, muscle strength and physical performance in older people : an umbrella review of systematic reviews and meta-analyses

Anton De SpiegeleerDavid BeckwéeIvan BautmansMirko Petrovic

A1 Journal Article in DRUGS & AGING

2016

Treating sarcopenia in clinical practice : where are we now?

Anton De SpiegeleerMirko PetrovicPauline BoeckxstaensNele Van Den Noortgate

A1 Journal Article in ACTA CLINICA BELGICA

2014

An in silico approach for modelling T-helper polarizing iNKT cell agonists

Anton De SpiegeleerEvelien WynendaeleMatthias VandekerckhoveSofie StalmansMaxime BoucartNele Van Den NoortgateKoen VenkenSerge Van CalenberghSANDRINE ASPESLAGHDirk Elewaut

A1 Journal Article in PLOS ONE

Prediction of fall rsik with six different biomarkers in mild cognitive impairment using principal component analysis

Anton De SpiegeleerTahir MasudPaul GreenhaffNele Van Den NoortgateMirko PetrovicVictoria HoodJohn GladmanVeronika van der WardtRowan HarwoodVictoria Booth

2013

A computational high-throughput screening approach of iNKT-agonists: a novel tool to find optimized iNKT cell ligands

Anton De SpiegeleerEvelien WynendaeleSofie StalmansNele Van Den NoortgateMatthias VandekerckhoveSerge Van CalenberghSANDRINE ASPESLAGHKoen VenkenDirk Elewaut

From immune senescence and insulin resistance to obesity and sarcopenia: iNKT cell as bridge?

Anton De SpiegeleerDirk ElewautPeggy JacquesGertjan De FlouNele Van Den Noortgate

2012

Adjuvantia of de queeste naar het ultieme vaccin

Anton De SpiegeleerMatthias VandekerckhoveSANDRINE ASPESLAGHDirk Elewaut

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

2009

The paradox of scored tablets: a cost-saving risk

Bart De SpiegeleerLindsay Van HoorebekeAnton De SpiegeleerPieter CasteleinLucas Van Bortel

A1 Journal Article in Pharmazie