Research Explorer

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Researcher

Ans De Beuckelaer

Awards & Distinctions

15 Results

2018

Hyaluronic acid conjugates of TLR7/8 agonists for targeted delivery to secondary lymphoid tissue

Euna YooAlex CD SalyerMichael JH BrushYupeng LiKathryn L TrautmanNikunj M ShuklaAns De BeuckelaerStefan LienenklausKim DeswarteBart Lambrecht et al.

A1 Journal Article in BIOCONJUGATE CHEMISTRY

Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties

Bo LouAns De BeuckelaerGeorge DakwarKatrien RemautJohan GrootenKevin BraeckmansBruno De GeestEnrico MastrobattistaStefaan De KokerWim E. Hennink

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2017

Arginine-rich peptide-based mRNA nanocomplexes efficiently instigate cytotoxic T cell immunity dependent on the amphipathic organization of the peptide

Vimal Kumar UdhayakumarAns De BeuckelaerJoanne McCaffreyCian M McCruddenJonathan L KirschmanDaryll VanoverLien Van HoeckeKenny RooseKim DeswarteBruno De Geest et al.

A1 Journal Article in ADVANCED HEALTHCARE MATERIALS

Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12

Stefaan De KokerLien Van HoeckeAns De BeuckelaerKenny RooseKim DeswarteMonique WillartPieter BogaertThomas NaessensBruno De GeestXavier Saelens et al.

A1 Journal Article in SCIENTIFIC REPORTS

Type I interferons modulate CD8⁺ T cell immunity to mRNA vaccines

Ans De BeuckelaerJohan GrootenStefaan De Koker

A1 Journal Article in TRENDS IN MOLECULAR MEDICINE

2016

Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice

Muriel SmetLien Van HoeckeAns De BeuckelaerSeppe Vander BekenThomas NaessensKarl VergoteMonique WillartBart LambrechtJan-Ake GustafssonKnut R Steffensen et al.

A2 Journal Article in IMMUNITY INFLAMMATION AND DISEASE

Coadministration of a plasmid encoding HIV-1 Gag enhances the efficacy of cancer DNA vaccines

Laure LambrichtKevin VanvarenbergAns De BeuckelaerLien Van HoeckeJohan GrootenBernard UcakarPascale LipnikNiek SandersStefan LienenklausVéronique Préat et al.

A1 Journal Article in MOLECULAR THERAPY

GM-CSF treatment prevents respiratory syncytial virus– induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation

Thomas NaessensBert SchepensMuriel SmetCharlotte PollardLien Van HoeckeAns De BeuckelaerMonique WillartBart LambrechtStefaan De KokerXavier Saelens et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mycobacterium tuberculosis-associated synthetic mycolates differentially exert immune stimulatory adjuvant activity

Muriel SmetCharlotte PollardAns De BeuckelaerLien Van HoeckeSeppe Vander BekenStefaan De KokerJuma'a R Al DulayymiKris HuygenJan VerschoorMark S Baird et al.

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

Spontaneous protein adsorption on graphene oxide nanosheets allowing efficient intracellular vaccine protein delivery

Hui LiKaat FierensZhiyue ZhangNane VanparijsMartijn SchuijsKatleen Van SteendamNatalia Feiner GraciaRiet De RyckeThomas De BeerAns De Beuckelaer et al.

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Type I interferons interfere with the capacity of mRNA lipoplex vaccines to elicit cytolytic T cell responses

Ans De BeuckelaerCharlotte PollardSandra Van LintKenny RooseLien Van HoeckeTom NaessensVimal Kumar UdhayakumarMuriel SmetNiek SandersStefan Lienenklaus et al.

A1 Journal Article in MOLECULAR THERAPY

mRNA-based vaccines to elicit CD8⁺ T cell immunity

Ans De BeuckelaerJohan GrootenStefaan De Koker

pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation

Lutz NuhnNane VanparijsAns De BeuckelaerLien LybaertGlenn VerstraeteKim DeswarteStefan LienenklausNikunj M ShuklaAlex CD SalyerBart Lambrecht et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2015

Comparison of VHH-Fc antibody production in Arabidopsis thaliana, Nicotiana benthamiana and Pichia pastoris

Thomas De MeyerBram LaukensJonah NolfEls Van LerbergeRiet De RyckeAns De BeuckelaerSylvie De BuckNico CallewaertAnna Depicker

A1 Journal Article in PLANT BIOTECHNOLOGY JOURNAL

The site of administration influences both the type and the magnitude of the immune response induced by DNA vaccine electroporation

Gaëlle VandermeulenKevin VanvarenbergAns De BeuckelaerStefaan De KokerLaure LambrichtCatherine UyttenhoveAnca ReschnerAlain VanderplasschenJohan GrootenVéronique Préat

A1 Journal Article in VACCINE