Research Explorer

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Researcher

Ans Baeyens

Publications & Research Data

Awards & Distinctions

93 Results

2025

Fibroblast-based radiosensitivity assays as a clinically valuable tool for (severe) combined immunodeficiency syndromes

Elien BeylsSomara De BeulVictoria BordonAlina FersterFilomeen HaerynckAnne VralAns Baeyens

A1 Journal Article in MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Investigating chromosomal radiosensitivity in inborn errors of immunity : insights from DNA repair disorders and beyond

Elien BeylsEvi DuthooLynn BackersKarlien Claes[missing] RAPID CliniciansTessa KerreB. LambrechtLevi HosteB. MeertensT. Van Genechten et al.

A1 Journal Article in JOURNAL OF CLINICAL IMMUNOLOGY

Replication stress, microcephalic primordial dwarfism, and compromised immunity in ATRIP deficient patients

Evi DuthooElien BeylsLynn BackersThorkell GudjónssonPeiquan HuangLeander JonckheereSebastian RiemannBram PartonLikun DuVeronique Debacker et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2024

Expanding molecular and clinical phenotype of Seckel syndrome : ATRIP deficient patient reveals novel insights in ATR signalling pathway

Kathleen ClaesLynn BackersElien BeylsEvi DuthooBram PartonVeronique DebackerKim De LeeneerMarieke De BruyneLevi HosteAns Baeyens et al.

Peripheral blood lymphocytes differ in DNA damage response after exposure to X-rays with different physical properties

Simon SioenLouise D'hondtFien Van HouteRobin DemuynckKlaus BacherCarlos De WagterAnne VralBarbara VanderstraetenDmitri KryskoAns Baeyens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

The micronucleus assay on cryopreserved whole blood

Renu DayalElien BeylsAnne VralAns Baeyens

A1 Journal Article in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

Variability in chromosomal radiosensitivity of breast cancer patients before and after radiotherapy

Renu DayalLiv VeldemanAnne VralAns Baeyens

2023

A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment

Elly De VlieghereKoen Van de VijverEva BlondeelNathan CarpentierRouba GhobeiraJarne PauwelsSebastian RiemannManon MinsartCharlotte FieuwsJohanna Mestach et al.

A1 Journal Article in BIOMATERIALS RESEARCH

Basic concepts of radiation biology

Ans BaeyensAna Margarida AbrantesVidhula AhireElizabeth A. AinsburySarah BaatoutBjorn BaseletMaria Filomena BotelhoTom BoterbergFrancois ChevalierFabiana Da Pieve et al.

Bookchapter in Radiobiology textbook

Impact of proton therapy on the DNA damage induction and repair in hematopoietic stem and progenitor cells

Simon SioenOniecha VanhoveBarbara VanderstraetenCarlos De WagterMonique EngelbrechtCharlot VandevoordeEvan De KockMarc-Jan Van GoethemAnne VralAns Baeyens

A1 Journal Article in SCIENTIFIC REPORTS

Individual radiation sensitivity and biomarkers : molecular radiation biology

Elizabeth A. AinsburyAna Margarida AbrantesSarah BaatoutAns BaeyensMaria Filomena BotelhoBenjamin FreyNicolas ForayAlexandros G. GeorgakilasFiona M. LyngInês Alexandra Marques et al.

Bookchapter in Radiobiology textbook

International comparison exercise for biological dosimetry after exposures with neutrons performed at two irradiation facilities as part of the BALANCE project

David EndesfelderUlrike KulkaMartin BucherUlrich GiesenGuy GartyChristina BeinkeMatthias PortGaetan GruelEric GregoireGeorgia Terzoudi et al.

A1 Journal Article in CYTOGENETIC AND GENOME RESEARCH

Molecular radiation biology

Judith ReindlAna Margarida AbrantesVidhula AhireOmid AzimzadehSarah BaatoutAns BaeyensBjorn BaseletVinita ChauhanFabiana Da PieveWendy Delbart et al.

Bookchapter in Radiobiology textbook

RENEB inter-laboratory comparison 2021 : inter-assay comparison of eight dosimetry assays

M PortJ-F BarquineroD EndesfelderJ MoquetU OestreicherG TerzoudiF TrompierAnne VralY AbeL Ainsbury et al.

A1 Journal Article in RADIATION RESEARCH

RENEB inter-laboratory comparison 2021 : the cytokinesis-block micronucleus assay

Anne VralD. EndesfelderJ. BalázsC. BeinkeC. Cuceu PetrenciF. FinotG. GartyL. HadjiiskaR. HristovaI. Ivanova et al.

A1 Journal Article in RADIATION RESEARCH

RENEB inter-laboratory comparison 2021 : the dicentric chromosome assay

D. EndesfelderU. OestreicherM. BucherC. BeinkeC. SiebenwirthE. AinsburyJ. MoquetG. GruelE. GregoireJ.S. Martinez et al.

A1 Journal Article in RADIATION RESEARCH

The variability in chromosomal radiosensitivity of breast cancer patients before and after radiotherapy

Renu DayalAnne VralAns Baeyens

2022

A novel S-micronucleus assay for radiosensitivity detection

Evi DuthooFilomeen HaerynckAnne VralAns Baeyens

An updated view into the cell cycle kinetics of human T lymphocytes and the impact of irradiation

Evi DuthooAnne VralAns Baeyens

A1 Journal Article in SCIENTIFIC REPORTS

Effects of modulated electro-hyperthermia (mEHT) on two and three year survival of locally advanced cervical cancer patients

Carrie Anne MinnaarInnocent MaposaJeffrey Allan KotzenAns Baeyens

A1 Journal Article in CANCERS

Fibroblast-based radiosensitivity assessment for primary immunodeficiency patients

Elien BeylsSomara De BeulFilomeen HaerynckVictoria BordonAlina FersterAnne VralAns Baeyens

Perillaldehyde is a new ferroptosis inducer with a relevant clinical potential for acute myeloid leukemia therapy

Elena CatanzaroEleonora TurriniTessa KerreSimon SioenAns BaeyensAlessandra GuerriniMohamed Lamin Abdi BellauGianni SacchettiGuglielmo PaganettoDmitri Krysko et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

2021

An updated view into the proliferative characteristics of human T lymphocytes and the effects of irradiation

Evi DuthooAnne VralAns Baeyens

Cryopreserved whole blood and isolated peripheral blood mononuclear cells as alternative sample types for the cytokinesis-block micronucleus assay

Elien BeylsSimon SioenAns BaeyensAnne Vral

DNA damage response of haematopoietic stem and progenitor cells to high-LET neutron irradiation

Monique EngelbrechtRoya NdimbaMaryna de KockXanthene MilesShankari NairRandall FisherPeter du PlessisJulie BolcaenMatthys Hendrik BothaElbie Zwanepoel et al.

A1 Journal Article in SCIENTIFIC REPORTS

The cytokinesis-block micronucleus assay for cryopreserved whole blood

Elien BeylsAns BaeyensAnne Vral

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

The cytokinesis-block micronucleus assay on human cryopreserved whole blood and isolated peripheral blood mononuclear cells

Simon SioenElien BeylsAnne VralAns Baeyens

2020

A novel EdU-based protocol for the investigation of cell cycle kinetics of irradiated human lymphocytes

Evi DuthooAnne VralAns Baeyens

Analysis of the effects of mEHT on the treatment-related toxicity and quality of life of HIV-positive cervical cancer patients

Carrie Anne MinnaarJeffrey KotzenThanushree NaidooMariza TunmerVinay SharmaMboyo-Di-Tamba VanguAns Baeyens

A1 Journal Article in INTERNATIONAL JOURNAL OF HYPERTHERMIA

First patient with bloom syndrome caused by a deep intronic variant leading to pseudoexon activation

Lynn BackersBram PartonStephanie VermeulenMarieke De BruyneSimon TavernierKris Van Den BogaertAnne VralAns BaeyensFilomeen HaerynckBart Lambrecht et al.

First patient with bloom syndrome caused by a deep intronic variant leading to pseudoexon activation

Lynn BackersBram PartonStephanie VermeulenMarieke De BruyneKris Van Den BogaertAnne VralAns BaeyensSimon TavernierFilomeen HaerynckKathleen Claes

Potentiation of the abscopal effect by modulated electro-hyperthermia in locally advanced cervical cancer patients

Carrie Anne MinnaarJeffrey KotzenOlusegun AyeniMboyo-Di-Tamba VanguAns Baeyens

A1 Journal Article in FRONTIERS IN ONCOLOGY

Rad51 foci as biomarkers for HR efficiency and radiosensitivity in individuals with a BRCA1 or BRCA2 mutation

Stephanie VermeulenValerie De MeyEvi DuthooAnne VralAns Baeyens

Radiosensitivity assessment in fibroblasts from patients with a primary immunodeficiency

Elien BeylsAns BaeyensAnne Vral

The cytokinesis-block micronucleus assay on human isolated fresh and cryopreserved peripheral blood mononuclear cells

Simon SioenKarlien CloetAnne VralAns Baeyens

A1 Journal Article in JOURNAL OF PERSONALIZED MEDICINE

The cytokinesis-block micronucleus assay on isolated fresh and frozen peripheral blood mononuclear cells

Simon SioenKarlien CloetAnne VralAns Baeyens

2019

A phase III randomised trial investigating the benefits of the addition of Oncothermia to chemo-radiation for cervical cancer in HIV positive and negative women in South Africa

Carrie Anne MinnaarAns BaeyensJeffrey Kotzen

Absence of genotoxic impact assessed by micronucleus frequency in circulating lymphocytes of workers exposed to cadmium

D LisonG Van Maele-FabryAnne VralStephanie VermeulenP BastinV HaufroidAns Baeyens

A1 Journal Article in TOXICOLOGY LETTERS

Assessment of radiation sensitivity in patients with a primary immunodeficiency disease

Anne VralAns BaeyensKathleen ClaesCarolien BonroyVictoria BonroyElien BeylsEvi DuthooLynn BackersStephanie VermeulenFilomeen Haerynck

Chromosomal radiosensitivity of triple negative breast cancer patients

Flavia Zita FranciesOlivia HerdAlan CairnsSarah NietzMarshall MurdochJacobus SlabbertKathleen ClaesAnne VralAns Baeyens

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Comparison of the cytokinesis block micronucleus assay on full blood versus PBMCs

Evi DuthooKarlien CloetSimon SioenAnne VralAns Baeyens

Defining characteristics of nodal disease on PET/CT scans in patients with HIV-positive and -negative locally advanced cervical cancer in South Africa

Carrie Anne MinnaarAns BaeyensOlusegun Akinwale AyeniJeffrey Allan KotzenMboyo-Di-Tamba Vangu

A1 Journal Article in TOMOGRAPHY

Development of an in vitro radiosensitivity assay on fibroblasts for patients with a primary immunodeficiency

Elien BeylsAns BaeyensAnne Vral

Effects of modulated electro-hyperthermia on disease control and disease-free survival in locally advanced cervical cancer patients : preliminary results

Carrie Anne MinnaarJeffrey KotzenAns Baeyens

Fluorescence in situ hybridisation study of micronuclei in C3A cells following exposure to ELF-magnetic fields

Luc VerschaeveRoel AntonissenAns BaeyensAnne VralAnnemarie Maes

A1 Journal Article in CARYOLOGIA

Radiation-induced DNA damage response of hematopoietic stem and progenitor cells after proton irradiation

Simon SioenMarc-Jan van GoethemCharlot VandevoordeAnne VralAns Baeyens

Radiation-induced DNA damage response of hematopoietic stem and progenitor cells after proton irradiation

Simon SioenCharlot VandevoordeAnne VralAns Baeyens

Radiosensitivity analysis in patients with a primary immunodeficiency disease

Anne VralAns BaeyensKathleen ClaesCarolien BonroyVictoria BordonElien BeylsEvi DuthooLynn BackersStephanie VermeulenFilomeen Haerynck

Receptor mediated radiosensitivity and DNA repair capacity of hormone dependent breast cancer cells

Stephanie VermeulenAnne VralAns Baeyens

The effect of modulated electro-hyperthermia on local disease control in HIV-positive and -negative cervical cancer women in South Africa : early results from a phase III randomised controlled trial

Carrie Anne MinnaarJeffrey Allan KotzenOlusegun Akinwale AyeniThanushree NaidooMariza TunmerVinay SharmaMboyo-Di-Tamba VanguAns Baeyens

A1 Journal Article in PLOS ONE

2018

Chromosomal radiosensitivity and instability in triple negative and/or young breast cancer and Fanconi Anaemia patients in South Africa

Flavia Zita FranciesAns BaeyensKathleen ClaesAnne Vral

Diagnosis of Fanconi Anaemia by ionising radiation- or mitomycin C-induced micronuclei

Flavia Zita FranciesRosalind WainwrightJanet PooleKim De LeeneerIlse CoeneGreet WiemeHélène A PoirelBénédicte BrichardStephanie VermeulenAnne Vral et al.

A1 Journal Article in DNA REPAIR

Diagnosis of Fanconi Anaemia by ionising radiation- or mitomycin C-induced micronuclei

Hyperthermia (mEHT) as a radiosensitser in HIV positive cervical cancer patients : effects/toxicities

Carrie Anne MinnaarAns BaeyensJeffrey Kotzen

Hyperthermia may potentiate the abscopal effect of ionising radiation in locally advanced cervical cancer patients

Carrie Anne MinnaarJeffrey KotzenAns Baeyens

Possible potentiation of the abscopal effect of ionising radiation by modulated electro-hyperthermia in locally advanced cervical cancer patients

Carrie Anne MinnaarJeffrey KotzenAns Baeyens

Radiation-induced DNA damage response of hematopoietic stem and progenitor cells after proton irradiation

Simon SioenAnne VralAns Baeyens

Radiation-induced leukemia : response of hematopoietic stem cells and progenitor cells to clinical therapy beams

Bram VerstraeteAnne VralDmitri KryskoAns Baeyens

Receptor mediated radiosensitivity and DNA repair capacity of breast cancer cell lines

Stephanie VermeulenAns Baeyens

2017

Chromosomal radiosensitivity and genomic instability of Fanconi anaemia patients in South Africa

Flavia FranciesRosalind WainwrightJeanet PooleJacobus SlabbertAns Baeyens

Micronucleus assay for Fanconi Anaemia diagnosis with ionising radiation and mitomycin C

Flavia FranciesRosalind WainwrightJeanet PooleJacobus SlabbertAns Baeyens

Radiation-induced DNA damage response of hematopoietic stem cells after proton irradiation

Bram VerstraeteCharlot VandevoordeJacobus SlabbertAnne VralAns Baeyens

RBE variations along the Bragg curve of a 200 MeV proton beam

Charlot VandevoordeAns BaeyensAnne VralJacobus Slabbert

RENEB intercomparison exercises analyzing micronuclei (Cytokinesis-block Micronucleus Assay)

Julie DepuydtAns BaeyensStephen BarnardChristina BeinkeAnett BenedekPhilip BeukesIwona BuraczewskaFirouz DarroudiStefania De SanctisInmaculada Dominguez et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

RENEB intercomparisons applying the conventional Dicentric Chromosome Assay (DCA)

Ursula OestreicherDaniel SamagaElizabeth AinsburyAna Catarina AntunesAns BaeyensLeonardo BarriosChristina BeinkePhilip BeukesWilliam F. BlakelyAlexandra Cucu et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

2016

Chromosomal radiosensitivity and genomic instability of Fanconi Anemia Patients in South Africa

Flavia FrancisRosalind WainwrightJanet PooleJacobus SlabbertAns Baeyens

Chromosomal radiosensitivity of human immunodeficiency virus positive/negative cervical cancer patients in South Africa

Olivia HerdFlavia FranciesJeffrey KotzenTrudy SmithZwide NxumaloXanthene MullerJacobus SlabbertAnne VralAns Baeyens

A1 Journal Article in MOLECULAR MEDICINE REPORTS

Interim statistical analysis on a phase III randomised trial investigating the addition of modulated electro-hyperthermia to chemoradiation for cervical cancer in HIV positive and negative women in South Africa

Carrie Anne MinnaarJeffrey KotzenAns Baeyens

The influence of blood storage time and general anaesthesia on chromosomal radiosensitivity assessment

Ans BaeyensOlivia HerdFlavia Zita FranciesAlan CairnsGary KatzmanMarshall MurdochDineshree PadiachyMike MorfordAnne VralJacobus P Slabbert

A1 Journal Article in MUTAGENESIS

2015

Analysis of radiosensitivity in South African cervical and breast cancer patients

Olivia Jayne HerdAns BaeyensAnne Vral

BRCA1, BRCA2 and PALB2 mutations and CHEK2 c. 1100delC in different South African ethnic groups diagnosed with premenopausal and/or triple negative breast cancer

FZ FranciesT WainsteinKim De LeeneerA CairnsM MurdochS NietzH CubaschBruce PoppeTom Van MaerkenBrecht Crombez et al.

A1 Journal Article in BMC CANCER

Chromosomal radiosensitivity of in vitro HIV infected cell lines

Ans BaeyensFlavia FrancisOlivia HerdJacobus Slabbert

Chromosomal radiosensitivity of lymphocytes in South African breast cancer patients of different ethnicity : an indirect measure of cancer susceptibility

FZ FranciesO HerdX MullerA CairnsM MurdochS NietzJP SlabbertAns Baeyens

Editorial material

Ethnical differences in breast cancer characteristics in South African population

Olivia HerdFlavia Z FranciesAlan CairnsXanthene MullerJacobus P SlabbertAns Baeyens

A1 Journal Article in BREAST JOURNAL

The effect of HIV and antiretroviral therapy on chromosomal radiosensitivity

Olivia HerdFlavia FrancisJacobus SlabbertAns Baeyens

A4 Journal Article in JOURNAL OF AIDS & CLINICAL RESEARCH

2013

Oncothermia in HIV-positive and -negative locally advanced cervical cancer patients in South Africa

Carrie A. StraussJeffrey A. KotzenAns BaeyensIrma Maré

A2 Journal Article in CONFERENCE PAPERS IN SCIENCE

2011

A semi-automated micronucleus-centromere assay to assess low-dose radiation exposure in human lymphocytes

Ans BaeyensRosemary SwansonOlivia HerdElizabeth AinsburyThulani MabhenguPascale WillemHubert ThierensJacobus P SlabbertAnne Vral

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Combined effect of polymorphisms in Rad51 and XRCC3 on breast cancer risk and chromosomal radiosensitivity

Anne VralPetra WillemsKathleen ClaesBruce PoppeAns BaeyensGianpaolo PerlettiHubert Thierens

A1 Journal Article in MOLECULAR MEDICINE REPORTS

2010

Chromosomal radiosensitivity of HIV positive individuals

Ans BaeyensJacobus P SlabbertPascale WillemSibusiso JozelaDebby Van Der MerweAnne Vral

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Semi-automated micronucleus-centromere scoring in assessing cellular damage in patients exposed to low doses of ionizing radiation

Ans BaeyensJakobus P SlabbertRose SwansonHubert ThierensPetra WillemsAnne Vral

2008

Polymorphisms in nonhomologous end-joining genes associated with breast cancer risk and chromosomal radiosensitivity

Petra WillemsKathleen ClaesAns BaeyensVeerle VandersickelJoke WerbrouckKim De RuyckBruce PoppeRudy Van den BroeckeAmin MakarEmanuela Marras et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

2005

Chromosomal radio sensitivity of breast cancer with a CHEK2 mutation

Ans BaeyensKathleen ClaesPetra WillemsKim De RuyckHubert ThierensAnne Vral

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS

Chromosomal radiosensitivity in breast cancer patients : influence of age of onset of the disease

Ans BaeyensRudy Van den BroeckeAmin MakarHubert ThierensLeo De RidderAnne Vral

A1 Journal Article in ONCOLOGY REPORTS

Effects of estradiol and progesterone on the variability of the micronucleus assay

Ans BaeyensVeerle VandersickelHubert ThierensLeo De RidderAnne Vral

A1 Journal Article in MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

In vitro chromosomal radiosensitivity in breast cancer patients

Ans BaeyensAnne VralHubert Thierens

2004

Chromosomal aberrations and in vitro radiosensitivity: intra-individual versus inter-individual variability

Anne VralHubert ThierensAns BaeyensLeo De Ridder

A1 Journal Article in TOXICOLOGY LETTERS

Chromosomal radiosensitivity in BRCA1 and BRCA2 mutation carriers

Ans BaeyensHubert ThierensKathleen ClaesBruce PoppeLeo De RidderAnne Vral

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

The use of EBV-transformed cell lines of breast cancer patients to measure chromosomal radiosensitivity

Ans BaeyensHubert ThierensKatia VandenbulckeLeo De RidderAnne Vral

A1 Journal Article in MUTAGENESIS

The use of IL-2 cultures to measure chromosomal radiosensitivity in breast cancer patients

Ans BaeyensKatia VandenbulckeJan PhilippéHubert ThierensLeo De RidderAnne Vral

A1 Journal Article in MUTAGENESIS

2002

Chromosomal radiosensitivity in breast cancer patients with a known or putative genetic predisposition

Ans BaeyensHubert ThierensKathleen ClaesBruce PoppeLudwine MessiaenLeo De RidderAnne Vral

A1 Journal Article in BRITISH JOURNAL OF CANCER

Chromosomal radiosensitivity study of temporary nuclear workers and the support of the adaptive response induced by occupational exposure.

Hubert ThierensAnne VralM BARBEM MEIJLAERSAns BaeyensLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Induction and disappearance of G2 chromatid breaks in lymphocytes after low doses of low-LET gamma-rays and high-LET fast neutrons.

Anne VralHubert ThierensAns BaeyensLeo De Ridder

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

The micronucleus and G(2)-phase assays for human blood lymphocytes as biomarkers of individual sensitivity to ionizing radiation: Limitations imposed by intraindividual variability.

Anne VralHubert ThierensAns BaeyensLeo De Ridder

A1 Journal Article in RADIATION RESEARCH