Research Explorer

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Researcher

Annick Verhee

Awards & Distinctions

24 Results

2024

Selective modulation of the human glucocorticoid receptor compromises GR chromatin occupancy and recruitment of p300/CBP and the Mediator complex

Laura Van MoortelAnnick VerheeJonathan ThommisRené HoutmanDiana MelchersLouis DelhayeChloé Van LeeneMadeleine HellemansKris GevaertSven Eyckerman et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

2023

A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state

Sandra Van LintAlexander Van ParysBram Van Den EeckhoutNiels VandammeStephane PlaisanceAnnick VerheeDominiek CatteeuwElke RoggeJennifer De GeestNele Vanderroost et al.

A1 Journal Article in MOLECULAR CANCER

2021

Targeting IFN activity to both B cells and plasmacytoid dendritic cells induces a robust tolerogenic response and protection against EAE

Anje CauwelsSandra Van LintElke RoggeAnnick VerheeBram Van Den EeckhoutShengru PangMarco PrinzNiko KleyGilles UzeJan Tavernier

A1 Journal Article in SCIENTIFIC REPORTS

2020

Rapid and effective generation of nanobody based CARs using PCR and Gibson Assembly

Stijn De MunterAlexander Van ParysLayla BralJoline IngelsGlenn GoetgelukSarah BonteMelissa PilleLore BillietKarin WeeningAnnick Verhee et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Safe eradication of large established tumors using neovasculature-targeted tumor necrosis factor-based therapies

Leander HuygheAlexander Van ParysAnje CauwelsSandra Van LintStijn De MunterJennyfer BultinckLennart ZabeauJeroen HostensAn GoethalsNele Vanderroost et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

2019

Targeting interferon activity to dendritic cells enables in vivo tolerization and protection against EAE in mice

Anje CauwelsSandra Van LintDominiek CatteeuwShengru PangFranciane PaulElke RoggeAnnick VerheeMarco PrinzNiko KleyGilles Uzé et al.

A1 Journal Article in JOURNAL OF AUTOIMMUNITY

2018

Delivering type I interferon to dendritic cells empowers tumor eradication and immune combination treatments

Anje CauwelsSandra Van LintFranciane PaulGenevieve GarcinStefaan De KokerAlexander Van ParysThomas WüestSarah GerloJosé Van Der HeydenYan Bordat et al.

A1 Journal Article in CANCER RESEARCH

2017

A safe and highly efficient tumor-targeted type I interferon immunotherapy depends on the tumor microenvironment

Anje CauwelsSandra Van LintGeneviève GarcinJennyfer BultinckFranciane PaulSarah GerloJosé Van Der HeydenYann BordatDominiek CatteeuwLode De Cauwer et al.

A1 Journal Article in ONCOIMMUNOLOGY

Analyzing trapped protein complexes by Virotrap and SFINX

Kevin TitecaEmmy Van QuickelbergheNoortje SamynDelphine De SutterAnnick VerheeKris GevaertJan TavernierSven Eyckerman

A1 Journal Article in NATURE PROTOCOLS

2016

Trapping mammalian protein complexes in viral particles

Sven EyckermanKevin TitecaEmmy Van QuickelbergheEva ClootsAnnick VerheeNoortje SamynLeentje De CeuninckEvy TimmermanDelphine De SutterSam Lievens et al.

A1 Journal Article in NATURE COMMUNICATIONS

2015

Leptin's metabolic and immune functions can be uncoupled at the ligand/receptor interaction level

Lennart ZabeauCathy J JensenSylvie SeeuwsKoen VenkenAnnick VerheeDominiek CatteeuwGeert van LooHui ChenKen WalderJacob Hollis et al.

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

2012

Selection of non-competitive leptin antagonists using a random nanobody-based approach

Lennart ZabeauAnnick VerheeDominiek CatteeuwLiesbeth FaesSylvie SeeuwsTine DecruyDirk ElewautFrank PeelmanJan Tavernier

A1 Journal Article in BIOCHEMICAL JOURNAL

2010

Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis

Delphine LavensFrank PeelmanJosé Van Der HeydenIsabel UyttendaeleDominiek CatteeuwAnnick VerheeB Van SchoubroeckJ KurthS HallenbergerR Clayton et al.

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2008

HyperISGylation of old world monkey ISG15 in human cells

Els PattynAnnick VerheeIsabel UyttendaeleJulie PiessevauxEvy TimmermanKris GevaertJoël VandekerckhoveFrank PeelmanJan Tavernier

A1 Journal Article in PLOS ONE

MAPPIT (MAmmalian Protein-Protein Interaction Trap) as a tool to study HIV reverse transcriptase dimerization in intact human cells

Els PattynDelphine LavensJosé Van Der HeydenAnnick VerheeSam LievensIrma LemmensS HALLENBERGERD JOCHMANSJan Tavernier

A1 Journal Article in JOURNAL OF VIROLOGICAL METHODS

2007

Mammalian protein-protein interaction trap (MAPPIT) analysis of STAT5, CIS, and SOCS2 interactions with the growth hormone receptor

Isabel UyttendaeleIrma LemmensAnnick VerheeAnne-Sophie De SmetJoël VandekerckhoveDelphine LavensFrank PeelmanJan Tavernier

A1 Journal Article in MOLECULAR ENDOCRINOLOGY

2005

Reverse MAPPIT: screening for protein-protein interaction modifiers in mammalian cells

Sven EyckermanIrma LemmensDominiek CatteeuwAnnick VerheeJoël VandekerckhoveSam LievensJan Tavernier

A1 Journal Article in NATURE METHODS

2004

Mapping of the leptin binding sites and design of a leptin antagonist

Frank PeelmanKatrien Van BenedenLennart ZabeauHannes IserentantPeter UlrichtsDelphine DefeauAnnick VerheeDominiek CatteeuwDirk ElewautJan Tavernier

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation by protein kinase CK2 modulates the activity of the ATP binding cassette A1 transporter

Stein RoosbeekFrank PeelmanAnnick VerheeChristine LabeurH CASTERMarc LensinkC CIRULLIJohan GrootenC COCHETJoël Vandekerckhove et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2002

Comparison of leptin- and interleukin-6-regulated expression of the rPAP gene family: evidence for differential co-regulatory signals

Daniël BroekaertSven EyckermanDelphine LavensAnnick VerheeWim WaelputJoël VandekerckhoveJan Tavernier

A1 Journal Article in EUROPEAN CYTOKINE NETWORK

2000

A sensitive and versatile bioassay for ligands that signal through receptor clustering

Xaveer Van OstadeLiesbeth SchauvliegeEls PattynAnnick VerheeJoël VandekerckhoveJan Tavernier

A1 Journal Article in JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Identification and expression analysis of leptin-regulated immediate early response and late target genes

Wim WaelputAnnick VerheeDaniël BroekaertSven EyckermanJoël VandekerckhoveJH BeattieJan Tavernier

A1 Journal Article in BIOCHEMICAL JOURNAL

1999

Analysis of Tyr to Phe and the fa/fa leptin receptor mutations in the PC12 cell line

Sven EyckermanWim WaelputAnnick VerheeDaniël BroekaertJoël VandekerckhoveJan Tavernier

A1 Journal Article in EUROPEAN CYTOKINE NETWORK

1998

Identification and regulation of expression of leptin induced genes in PC12 cells

Wim WaelputAnnick VerheeDaniël BroekaertSven EyckermanJoël VandekerckhoveJan Tavernier