Research Explorer

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Researcher

Anneleen Heldens

Awards & Distinctions

12 Results

2025

Mitochondrial dysfunction characterizes the multigenerational effects of maternal obesity on MASLD

Anneleen HeldensMilton Boaheng AntwiLouis OnghenaTim MeeseYannick GansemansJoél SmetEllen DupontXavier VerhelstSarah RaevensHans Van Vlierberghe et al.

U Journal Article in JHEP Reports

PPARα-ERRα crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression

Milton Boaheng AntwiSander LefereDorien ClarisseLisa KoorneefAnneleen HeldensLouis OnghenaKylian DecroixDaria FijalkowskaJonathan ThommisMadeleine Hellemans et al.

A1 Journal Article in METABOLISM-CLINICAL AND EXPERIMENTAL

Pathophysiology and complications of metabolic dysfunction-associated steatotic liver disease

Anneleen HeldensAnja GeertsRuth De BruyneSander Lefere

The pan-PPAR agonist lanifibranor reduces portal pressure independent of fibrosis reduction through the splanchnic vasculature

Anneleen HeldensChristophe CasteleynLouis OnghenaMilton Boaheng AntwiSara NeytBenedicte DescampsChristian VanhoveXavier VerhelstSarah RaevensHans Van Vlierberghe et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

2024

Adipose tissue insulin resistance correlates with disease severity in pediatric metabolic dysfunction-associated steatotic liver disease : a prospective cohort study

Anneleen HeldensEllen DupontLindsey DevisscherMaarten BuytaertXavier VerhelstSarah RaevensHans Van VlierbergheAnja GeertsRuth De BruyneSander Lefere

A1 Journal Article in JOURNAL OF PEDIATRICS

The double-edged sword of bariatric surgery : extending the excluded limb can trigger bacterial translocation, liver inflammation and death

Louis OnghenaAnneleen HeldensMilton Boaheng AntwiLindsey DevisscherHans Van VlierbergheSarah RaevensXavier VerhelstAnne HoorensYves Van NieuwenhoveAnja Geerts et al.

Transgenerational maternal obesity induces mitochondrial dysfunction and aggravates MASLD, which can be reversed by metabolic drug candidates

Anneleen HeldensMilton Boaheng AntwiLouis OnghenaLindsey DevisscherXavier VerhelstSarah RaevensHans Van VlierbergheRuth De BruyneAnja GeertsSander Lefere

2023

Novel bariatric surgery models in mice-differential effects on body weight loss and fatty liver disease

Louis OnghenaAnneleen HeldensMilton Boaheng AntwiHans Van VlierbergheXavier VerhelstLindsey DevisscherYves Van NieuwenhoveAnja GeertsSander Lefere

The pan-PPAR agonist lanifibranor decreases portal pressure in models of both hepatic and prehepatic portal hypertension

Anneleen HeldensChristophe CasteleynLouis OnghenaMilton Boaheng AntwiBenedicte DescampsChristian VanhoveXavier VerhelstHans Van VlierbergheLindsey DevisscherJean-Louis Junien et al.

2022

Adipose tissue insulin resistance is a determinant of disease severity in pediatric nonalcoholic fatty liver disease

Anneleen HeldensEllen DupontLindsey DevisscherAnja GeertsRuth De BruyneXavier VerhelstHans Van VlierbergheSander Lefere

MD2 AMP(K)s up the link between lipid accumulation and inflammation in NAFLD COMMENT

Anneleen HeldensSander Lefere

Editorial material

2020

Anesthesie bij de obese hond en kat = Anesthesia of obese dogs and cats

Anneleen HeldensTom RoggemanIngeborgh Polis

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT