Research Explorer

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Researcher

Annekatrien Boel

35 Results

2021

Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells

Swati MishraJasin TaelmanMina PopovicLaurentijn TillemanEvi DuthooMargot Van der JeughtDieter DeforceFilip Van NieuwerburghBjörn MentenPetra De SutterAnnekatrien BoelSusana Marina Chuva de Sousa LopesBjörn Heindryckx

A1 Journal Article in STEM CELLS

Arterial tortuosity syndrome : an ascorbate compartmentalization disorder?

Annekatrien BoelKrisztina VeszelyiCsilla E. NemethAude BeyensAndy WillaertPaul CouckeBert CallewaertEva Margittai

A1 Journal Article in ANTIOXIDANTS & REDOX SIGNALING

Comparative analysis of mouse and human preimplantation development following POU5F1 CRISPR/Cas9 targeting reveals interspecies differences

Panagiotis StamatiadisAnnekatrien BoelGwenny CosemansMina PopovicBieke BekaertRamesh Reddy GuggillaMaoxing TangPetra De SutterFilip Van NieuwerburghBjörn MentenDominic StoopSusana Marina Chuva de Sousa LopesPaul CouckeBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION

Cutis laxa : a comprehensive overview of clinical characteristics and pathophysiology

Aude BeyensAnnekatrien BoelSofie SymoensBert Callewaert

A1 Journal Article in CLINICAL GENETICS

Digital polymerase chain reaction for assessment of mutant mitochondrial carry-over after nuclear transfer for In Vitro fertilization

Olivier TytgatMX TangWillem van SnippenbergAnnekatrien BoelRR GuggillaYannick GansemansMichiel Van HerpSofie SymoensWim TrypsteenDieter DeforceBjörn HeindryckxPaul CouckeWard De SpiegelaereFilip Van Nieuwerburgh

A1 Journal Article in CLINICAL CHEMISTRY

Lrp5 mutant and crispant zebrafish faithfully model human osteoporosis, establishing the zebrafish as a platform for CRISPR‐based functional screening of osteoporosis candidate genes

Jan Willem BekChen ShochatAdelbert De ClercqHanna De SaffelAnnekatrien BoelJuriaan MetzFrans RodenburgDavid KarasikAndy WillaertPaul Coucke

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

Prospects of germline nuclear transfer in women with diminished ovarian reserve

Antonia ChristodoulakiAnnekatrien BoelMaoxing TangChloë De RooDominic StoopBjörn Heindryckx

A1 Journal Article in FRONTIERS IN ENDOCRINOLOGY

Sex-specific isolation and propagation of human premeiotic fetal germ cells and germ cell-like cells

Swati MishraJasin TaelmanYolanda W. ChangAnnekatrien BoelPetra De SutterBjörn HeindryckxSusana Marina Chuva de Sousa Lopes

A1 Journal Article in CELLS

2020

Chromosomal mosaicism in human blastocysts : the ultimate diagnostic dilemma

Mina PopovicLien DhaenensAnnekatrien BoelBjörn MentenBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION UPDATE

Chromosomal mosaicism in human blastocysts : the ultimate diagnostic dilemma (vol 26, pg 313, 2020)

Mina PopovicLien DhaenensAnnekatrien BoelBjörn MentenBjörn Heindryckx

Comparative study of preimplantation development following distinct assisted oocyte activation protocols in a PLC-zeta knockout mouse model

Minerva Ferrer BuitragoLaurentijn TillemanVanessa ThysA HachemAnnekatrien BoelFilip Van NieuwerburghDieter DeforceLuc LeybaertPetra De SutterJ. ParringtonBjörn Heindryckx

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Correcting PLCζ mutation in the germ line to overcome transmission of hereditary infertility in mice

Bieke BekaertAnnekatrien BoelVanessa ThysPanagiotis StamatiadisSusana Marina Chuva de Sousa LopesPetra De SutterJohn ParringtonBjörn MentenDominic StoopPaul CouckeBjörn Heindryckx

Diagnosis and treatment of male infertility-related fertilization failure

Arantxa Cardona BarberánAnnekatrien BoelFrauke Vanden MeerschautDominic StoopBjörn Heindryckx

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

Germline nuclear transfer in mice may rescue poor embryo development associated with advanced maternal age and early embryo arrest

Maoxing TangMina PopovicPanagiotis StamatiadisMargot Van der JeughtRudy Van CosterDieter DeforcePetra De SutterPaul CouckeBjörn MentenDominic StoopAnnekatrien BoelBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION

Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos

Thomas NaertDieter TulkensNicole A. EdwardsMarjolein CarronNikko-Ideen ShaidaniMarcin WlizlaAnnekatrien BoelSuzan DemuynckMarko E. HorbPaul CouckeAndy WillaertAaron M. ZornKris Vleminckx

A1 Journal Article in SCIENTIFIC REPORTS

Slc2a10 knock-out mice deficient in ascorbic acid synthesis recapitulate aspects of arterial tortuosity syndrome and display mitochondrial respiration defects

Annekatrien BoelJoyce BurgerMarine VanhomwegenAude BeyensMarjolijn RenardSander BarnhoornChristophe CasteleynDieter ReinhardtBenedicte DescampsChristian VanhoveIngrid van der PluijmPaul CouckeAndy WillaertJeroen EssersBert Callewaert

A1 Journal Article in HUMAN MOLECULAR GENETICS

Vitrification negatively affects the Ca2+-releasing and activation potential of mouse oocytes, but vitrified oocytes are potentially useful for diagnostic purposes

Davina BonteVanessa ThysPetra De SutterAnnekatrien BoelLuc LeybaertBjörn Heindryckx

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

2019

Animal disease modeling of the arterial tortuosity syndrome : advancing the CRISPR/Cas9 system for improved genome editing

Annekatrien BoelPaul CouckeAndy Willaert

Arterial tortuosity syndrome : 40 new families and literature review (vol 20, pg 1236, 2017)

Aude BeyensJuliette AlbuissonAnnekatrien BoelMazen Al-EssaWaheed Al-ManeaDamien BonnetOzlem BostanOdile BouteTiffany BusaNathalie CanhamErgun CilPaul CouckeMargot A. CousinMajed DasoukiJulie De BackerAnne De PaepeSofie De SchepperDeepthi De SilvaKoenraad DevriendtInge De WandeleDavid R. DeyleHarry DietzSophie Dupuis-GirodEudice FontenotBjörn Fischer-ZirnsakAlper GezdiriciJamal GhoumidFabienne GiulianoNeus BaenaMohammed Z. HaiderJoshua S. HardinXavier JeunemaitreEric W. KleeUwe KornakManuel F. LandechoAnne LegrandBart LoeysStanislas LyonnetHelen MichaelPamela MoceriShehla MohammedLaura Muiño-MosqueraSheela NampoothiriKarin PichlerKatrina PrescottAnna RajebMaria Ramos-ArroyoMassimiliano RossiMustafa SalihMohammed Z. SeidahmedElise SchaeferElisabeth Steichen-GersdorfSehime TemelFahrettin UysalMarine VanhomwegenLut Van LaerLionel Van MaldergemDavid WarnerAndy WillaertTom R. Collins IIAndrea TaylorElaine C. DavisYuri ZarateBert Callewaert

Assisted oocyte activation significantly increases fertilization and pregnancy outcome in patients with low and total failed fertilization after intracytoplasmic sperm injection : a 17-year retrospective study

Davina BonteMinerva Ferrer BuitragoLien DhaenensMina PopovicVanessa ThysIlse De CrooStefanie De GheselleNathalie SteyaertAnnekatrien BoelFrauke Vanden MeerschautPetra De SutterBjörn Heindryckx

A1 Journal Article in FERTILITY AND STERILITY

Comparative analysis of different nuclear transfer techniques to prevent the transmission of mitochondrial DNA variants

Maoxing TangR ReddyYannick GansemansMargot Van der JeughtAnnekatrien BoelPanagiotis StamatiadisRudy Van CosterDieter DeforceFilip Van NieuwerburghPetra De SutterBjörn Heindryckx

Comparative analysis of different nuclear transfer techniques to prevent the transmission of mitochondrial DNA variants

Maoxing TangRamesh Reddy GuggillaYannick GansemansMargot Van der JeughtAnnekatrien BoelMina PopovicPanagiotis StamatiadisMinerva Ferrer BuitragoVanessa ThysRudy Van CosterDieter DeforcePetra De SutterFilip Van NieuwerburghBjörn Heindryckx

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

De novo and inherited pathogenic variants in KDM3B cause intellectual disability, short stature, and facial dysmorphism

Illja J DietsRoos van der DonkKristina BaltrunaiteEsmé WaandersMargot RF ReijndersAlexander JM DingemansRolph PfundtAnneke T Vulto-van SilfhoutLaurens WielChristian GilissenJulien ThevenonLaurence PerrinAlexandra AfenjarCaroline NavaBoris KerenSarah BartzBethany PeriGea BeundersNienke VerbeekKoen van GassenIsabelle ThiffaultMaxime Cadieux-DionLina Huerta-SaenzMatias WagnerVassiliki KonstantopoulouJulia VodopiutzMatthias GrieseAnnekatrien BoelBert CallewaertHan G BrunnerTjitske KleefstraNicoline HoogerbruggeBert BA de VriesVivian HwaAndrew DauberJayne Y Hehir-KwaRoland P KuiperMarjolijn CJ Jongmans

A1 Journal Article in AMERICAN JOURNAL OF HUMAN GENETICS

Decreased nuclear ascorbate accumulation accompanied with altered genomic methylation pattern in fibroblasts from arterial tortuosity syndrome patients

Csilla NémethZsófia NemodaPéter LőwPál SzabóErzsébet HorváthAndy WillaertAnnekatrien BoelBert CallewaertPaul CouckeMarina ColombiGábor BánhegyiÉva Margittai

A1 Journal Article in OXIDATIVE MEDICINE AND CELLULAR LONGEVITY

Increased primordial germ cell (PGC) specification from human embryonic stem cells (hESC) derived in Activin A

Swati MishraMargot Van der JeughtMina PopovicJasin TaelmanEvi DuthooKatarzyna Szymańska-VandendriesschePetra De SutterLaurentijn TillemanFilip Van NieuwerburghAnnekatrien BoelSM Chuva de Sousa LopesBjörn Heindryckx

The use of pronuclear transfer to overcome infertility disorders in mice

Björn HeindryckxAnnekatrien BoelPanagiotis StamatiadisMargot Van der JeughtRamesh Reddy GuggillaDieter DeforceRudy Van CosterPetra De Sutter

2018

Arterial tortuosity syndrome : 40 new families and literature review

Aude BeyensJuliette AlbuissonAnnekatrien BoelMazen Al-EssaWaheed Al-ManeaDamien BonnetOzlem BostanOdile BouteTiffany BusaNathalie CanhamErgun CilPaul CouckeMargot A CousinMajed DasoukiJulie De BackerAnne De PaepeSofie De SchepperDeepthi De SilvaKoenraad DevriendtInge De WandeleDavid R DeyleHarry DietzSophie Dupuis-GirodEudice FontenotBjörn Fischer-ZirnsakAlper GezdiriciJamal GhoumidFabienne GiulianoNeus BaenaMohammed Z HaiderJoshua S HardinXavier JeunemaitreEric W KleeUwe KornakManuel F LandechoAnne LegrandBart LoeysStanislas LyonnetHelen MichaelPamela MoceriShehla MohammedLaura Muiño MosqueraSheela NampoothiriKarin PichlerKatrina PrescottAnna RajebMaria Ramos-ArroyoMassimiliano RossiMustafa SalihMohammed Z SeidahmedElise SchaeferElisabeth Steichen-GersdorfSehime TemelFahrettin UysalMarine VanhomwegenLut Van LaerLionel Van MaldergemDavid WarnerAndy WillaertTom R CollinsAndrea TaylorElaine C DavisYuri ZarateBert Callewaert

A1 Journal Article in GENETICS IN MEDICINE

BATCH-GE : analysis of NGS data for genome editing assessment

Wouter SteyaertAnnekatrien BoelPaul CouckeAndy Willaert

Bookchapter in Xenopus : methods and protocols

CRISPR/Cas9-mediated homology-directed repair by ssODNs in zebrafish induces complex mutational patterns resulting from genomic integration of repair-template fragments

Annekatrien BoelHanna De SaffelWouter SteyaertBert CallewaertAnne De PaepePaul CouckeAndy Willaert

A1 Journal Article in DISEASE MODELS & MECHANISMS

2017

Arterial tortuosity syndrome : 37 new families and literature review

Aude BeyensJuliette AlbuissonT BusaN CanhamJM ChopinM DasoukiK DevriendtH DietzBjörn Fischer-ZirnsakAlper GezdiriciF GiulianoM GuitartMZ Seid AhmedE SchaeferE Steichen-GersdorfLionel Van MalderghemDavid WarnerM ZaiderAnne De PaepeLaura Muiño MosqueraJulie De BackerAnnekatrien BoelAndy WillaertPaul CouckeAndrea TaylorElaine C DavisYuri ZarateBert Callewaert

Arterial tortuosity syndrome : 40 new families and literature review

Aude BeyensJuliette AlbuissonAnnekatrien BoelMazen Al-EssaDamien BonnetO BostanOdile BouteT BusaN CanhamErgun CilPaul CouckeMargot A CousinM DasoukiJulie De BackerAnne De PaepeSofie De SchepperDeepthi De SilvaKoen DevriendtInge De WandeleDavid R DeyleH DietzS Dupuis-GirodE FontenotBjörn Fischer-ZirnsakAlper GezdiriciJ GhoumidF GiulianoM GuitartMZ HaiderJS HardinXavier JeunemaitreEric W KleeUwe KornakMF LandechoA LegrandBart LoeysS LyonnetHelen MichaelPamela MoceriS MohammedLaura Muiño MosqueraS NampoothiriK PichlerK PrescottAnna RajebM Ramos-ArroyoM RossiM SalihMZ Seid AhmedE SchaeferE Steichen-GersdorfSehime TemelFahrettin UysalMarine VanhomwegenLut Van LaerLionel Van MalderghemDavid WarnerAndy WillaertTom CollinsAndrea TaylorElaine C DavisYuri ZarateBert Callewaert

2016

Arterial tortuosity syndrome : 29 novel families

Aude BeyensJuliette AlbuissonT BusaN CanhamJM CM. DasoukiK DevriendtH DietzBjörn Fischer-ZirnsakAlper GezdiriciF GiulianoM GuitartMZ HaiderJ HardinH MichaelX JeunemaitreUwe KornakMF LandechoS LyonnetS MohammedS NampoothiriK PichlerK PrescottM RamosM RossiM SalihMZ Seid AhmedE SchaeferE Steichen-GersdorfLionel Van MalderghemDavid WarnerM ZaiderAnne De PaepeLaura Muiño MosqueraJulie De BackerAndy WillaertAnnekatrien BoelPaul CouckeAndrea TaylorElaine C DavisYuri ZarateBert Callewaert

BATCH-GE : batch analysis of next-generation sequencing data for genome editing assessment

Annekatrien BoelWouter SteyaertNina De RockerBjörn MentenBert CallewaertAnne De PaepePaul CouckeAndy Willaert

A1 Journal Article in SCIENTIFIC REPORTS

CRISPR-Cas9 modeling of cell lines and zebrafish to study the TLX1-PHF6 cooperative interrelationship in T-cell acute lymphoblastic leukemia

Siebe LoontiensKaat DurinckNina De RockerAnnekatrien BoelEls JanssensSuzanne VanhauwaertPieter RondouCharles De BockInge Van de WalleFinola MooreDavid LangenauJan CoolsTom TaghonBjörn MentenAndy WillaertPaul CouckePieter Van VlierbergheFranki Speleman

CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis

Thomas NaertRobin ColpaertTom Van NieuwenhuysenDionysia DimitrakopoulouJannick LeoenJurgen HaustraeteAnnekatrien BoelWouter SteyaertTrees LepezDieter DeforceAndy WillaertDavid CreytensKris Vleminckx

A1 Journal Article in SCIENTIFIC REPORTS