Research Explorer

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Researcher

Anne Sieben

Awards & Distinctions

57 Results

2022

Mutations in RNU7-1 weaken secondary RNA structure, induce MCP-1 and CXCL10 in CSF, and result in Aicardi-Goutières syndrome with severe end-organ involvement

Leslie NaesensJosephine NemegeerFilip RoelensLore VallaeysMarije MeuwissenKatrien JanssensPATRICK VERLOOBenson OgunjimiDimitri HemelsoetLevi Hoste et al.

A1 Journal Article in JOURNAL OF CLINICAL IMMUNOLOGY

Therapy-induced electrophysiological changes in primary progressive aphasia : a preliminary study

Jara StalpaertSofie StandaertLien D’HelftMarijke MiattonAnne SiebenTim Van LangenhoveWouter DuyckPieter van MierloMiet De Letter

A1 Journal Article in FRONTIERS IN HUMAN NEUROSCIENCE

2021

A case series of verbal semantic processing in primary progressive aphasia : evidence from the N400 effect

Jara StalpaertElissa-Marie CocquytMarijke MiattonAnne SiebenTim Van LangenhovePieter van MierloMiet De Letter

A1 Journal Article in INTERNATIONAL JOURNAL OF LANGUAGE & COMMUNICATION DISORDERS

Hippocampal sclerosis in frontotemporal dementia : when vascular pathology meets neurodegeneration

Anne SiebenTim Van LangenhoveYannick VermeirenHelena GossyeMarleen PraetDimitri VanhauwaertCeline CousaertSebastiaan EngelborghsRobrecht RaedtPaul Boon et al.

A1 Journal Article in JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Novel mutations in RNU7-1 weaken secondary RNA structure, induce MCP-1 and CXCL10 in CSF and result in Aicardi-Goutières syndrome with severe end-organ involvement

Leslie NaesensJosephine NemegeerFilip RoelensLore VallaeysMarije MeuwissenKatrien JanssensPATRICK VERLOOBenson OgunjimiDimitri HemelsoetProgram for Undiagnosed Rare Diseases (UD-PrOZA) et al.

Proteinopathies of frontotemporal lobar degeneration : investigating the impact of vascular contributions

Anne SiebenPaul BoonPeter De DeynPatrick Santens

The electrophysiological correlates of phoneme perception in primary progressive aphasia : a preliminary case series

Jara StalpaertMarijke MiattonAnne SiebenTim Van LangenhovePieter van MierloMiet De Letter

A1 Journal Article in FRONTIERS IN HUMAN NEUROSCIENCE

2020

A genetic answer to a neuropsychiatric challenge

Hannah DhaeneCéline CousaertHannelore TandtTim Van LangenhoveMarijke MiattonHelena GosseyeGilbert LemmensAnne Sieben

A2 Journal Article in ACTA PSYCHIATRICA BELGICA

Amyloid-β1–43 cerebrospinal fluid levels and the interpretation of APP, PSEN1 and PSEN2 mutations

Federica PerroneMaria BjerkeElisabeth HensAnne SiebenMaarten TimmersArne De RoeckRik VandenbergheKristel SleegersJean-Jacques MartinPeter P. De Deyn et al.

A1 Journal Article in ALZHEIMERS RESEARCH & THERAPY

End of dose interval symptoms in patients treated with natalizumab : a role for serum cytokines?

Cathérine DekeyserAnnelien De PueAnne SiebenLuc AlgoedLiesbeth Van HijfteSarah GerloGuy Laureys

A1 Journal Article in MULTIPLE SCLEROSIS AND RELATED DISORDERS

Homozygous and compound heterozygous rare variants in VPS13C contribute to Lewy body diseases

Stefanie SmoldersStéphanie PhiltjensDavid CrosiersAnne SiebenElisabeth HensBavo HeemanSara Van MosseveldePhilippe PalsBob AsselberghRoberto Dos Santos Dias et al.

Long lasting trigeminal neuropathy, limbic encephalitis and abdominal ganglionitis without primary cancer : an atypical case of Hu-Antibody syndrome

Elien De SchamphelaereAnne SiebenSebastien HeyndrickxMartin LammensKarel GeboesJan De Bleecker

A1 Journal Article in CLINICAL NEUROLOGY AND NEUROSURGERY

2019

Dementia, end of life, and euthanasia : a survey among dementia specialists organized by the Belgian Dementia Council

Gaëtane PicardJean-Christophe BierIsabelle CapronPeter Paul De DeynOlivier DeryckSebastiaan EngelborghsBernard HanseeuwJean-Claude LemperEric MormontMirko Petrovic et al.

A1 Journal Article in JOURNAL OF ALZHEIMERS DISEASE

Loss of DPP6 in neurodegenerative dementia : a genetic player in the dysfunction of neuronal excitability

Rita CacaceBavo HeemanSara Van MosseveldeArne De RoeckJulie HoogmartensPeter De RijkHelena GossyeKristof De VosWouter De CosterMojca Strazisar et al.

A1 Journal Article in ACTA NEUROPATHOLOGICA

2018

An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer's disease

Arne De RoeckLena DuchateauJasper Van DongenRita CacaceMaria BjerkeTobi Van den BosschePatrick CrasRik VandenberghePeter P De DeynSebastiaan Engelborghs et al.

A1 Journal Article in ACTA NEUROPATHOLOGICA

Clinical variability and onset age modifiers in an extended Belgian GRN founder family

Eline WautersSara Van MosseveldeKristel SleegersJulie van der ZeeSebastiaan EngelborghsAnne SiebenRik VandenbergheStephanie PhiltjensMarleen Van den BroeckKarin Peeters et al.

A1 Journal Article in NEUROBIOLOGY OF AGING

Common and rare TBK1 variants in early-onset Alzheimer disease in a European cohort

Jan VerheijenJulie van der ZeeIlse GijselinckTobi Van den BosscheLubina DillenBavo HeemanEstrella Gómez-TortosaAlbert LladóRaquel Sanchez-ValleCaroline Graff et al.

A1 Journal Article in NEUROBIOLOGY OF AGING

Extended FTLD pedigree segregating a Belgian GRN-null mutation : neuropathological heterogeneity in one family

Anne SiebenSara Van MosseveldeEline WautersSebastiaan EngelborghsJulie van der ZeeTim Van LangenhovePatrick SantensMarleen PraetPaul BoonMarijke Miatton et al.

A1 Journal Article in ALZHEIMERS RESEARCH & THERAPY

No supportive evidence for TIA1 gene mutations in a European cohort of ALS-FTD spectrum patients

Yalda Baradaran-HeraviLubina DillenHung Phuoc NguyenSara Van MosseveldeJonathan BaetsPeter De JongheSebastiaan EngelborghsPeter P De DeynMathieu VandenbulckeRik Vandenberghe et al.

A1 Journal Article in NEUROBIOLOGY OF AGING

Teenage-onset progressive myoclonic epilepsy due to a familial C9orf72 repeat expansion

Jelle van den AmeeleIvana JedlickovaAnna PristoupilovaAnne SiebenSara Van MosseveldeChantal Ceuterick-de GrooteHelena HůlkováRadoslav MatejAlfred MeursChristine Van Broeckhoven et al.

A1 Journal Article in NEUROLOGY

2017

Alzheimer’s disease and driving : review of the literature and consensus guideline from Belgian dementia experts and the Belgian road safety institute endorsed by the Belgian Medical Association

Jan VersijptMark TantIngo BeyerJean-Christophe BierPatrick CrasPeter P. De DeynPatrick De WitOlivier DeryckBernard HanseeuwMargareta Lambert et al.

A1 Journal Article in ACTA NEUROLOGICA BELGICA

Bilingualism and cognitive decline : a story of pride and prejudice

Evy WoumansJan VersijptAnne SiebenPatrick SantensWouter Duyck

Editorial material

Clinical evidence of disease anticipation in families segregating a C9orf72 repeat expansion

Sara Van MosseveldeJulie van der ZeeIlse GijselinckKristel SleegersJan De BleeckerAnne SiebenRik VandenbergheTim Van LangenhoveJonathan BaetsOlivier Deryck et al.

A1 Journal Article in JAMA NEUROLOGY

Impaired processing of serial order determines working memory impairments in Alzheimer’s disease

Maya De BelderPatrick SantensAnne SiebenWim Fias

A1 Journal Article in JOURNAL OF ALZHEIMERS DISEAS

Investigating the role of ALS genes CHCHD10 and TUBA4A in Belgian FTD-ALS spectrum patients

Federica PerroneHung Phuoc NguyenSara Van MosseveldeMatthieu MoisseAnne SiebenPatrick SantensJan De BleeckerMathieu VandenbulckeSebastiaan EngelborghsJonathan Baets et al.

A1 Journal Article in NEUROBIOLOGY OF AGING

2016

106 FTD cases with refined neuropathological confirmation

Anne SiebenS. Van MosseveldeJ. van der ZeeJ. GoossensP. P. De DeynP. CrasS. EngelborghsC. Van BroeckhovenJ. -J. Martin

A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer's disease

Jan VerheijenTobi Van den BosscheJulie van der ZeeSebastiaan EngelborghsRaquel Sanchez-ValleAlbert LladoCaroline GraffHakan ThonbergPau PastorSara Ortega-Cubero et al.

A1 Journal Article in ACTA NEUROPATHOLOGICA

Alzheimer's disease, apolipoprotein E and hormone replacement therapy

Herman DepypereAnne VierinSteven WeyersAnne Sieben

A1 Journal Article in MATURITAS

Clinical features of TBKI carriers compared with C9orf72, GRN and non-mutation carriers in a Belgian cohort

Sara Van MosseveldeJulie van der ZeeIlse GijselinckSebastiaan EngelborghsAnne SiebenTim Van LangenhoveJan De BleeckerJonathan BaetsMathieu VandenbulckeKoen Van Laere et al.

A1 Journal Article in BRAIN

Dementia : diagnosis, behaviour management, ethical issues

Jean-Pierre BaeyensJean-Christophe BierDaniel BrandJan De LepeleireJacques De MolEva DierckxSebastiaan EngelborghsChristian GillesLieve LemeyMirko Petrovic et al.

Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD

S BoeynaemsElke BogaertE MichielsI GijselinckAnne SiebenA JovičićG De BaetsW ScheveneelsJ SteyaertI Cuijt et al.

A1 Journal Article in SCIENTIFIC REPORTS

Mutated CTSF in adult-onset neuronal ceroid lipofuscinosis and FTD

Julie van der ZeePeter MarienRoeland CrolsSara Van MosseveldeLubina DillenFederica PerroneSebastiaan EngelborghsJo VerhoevenTine D'aesChantal Ceuterick-De Groote et al.

A2 Journal Article in NEUROLOGY-GENETICS

PSP and small vessel disease : more than occasional co-occurence?

Anne SiebenPatrick SantensDimitri HemelsoetSebastiaan EngelborghsPeter De JongheJan De BleeckerJen MaesChristina JadoulPatrick CrasPeter-Paul De Deyn et al.

Phenotypic characteristics of Alzheimer patients carrying an ABCA7 mutation

Tobi Van den BosscheKristel SleegersElise CuyversSebastiaan EngelborghsAnne SiebenArne De RoeckCaroline Van CauwenbergheSteven VermeulenMarleen Van den BroeckAnnelies Laureys et al.

A1 Journal Article in NEUROLOGY

The C9orf72 repeat size correlates with onset age of disease, DNA methylation and transcriptional downregulation of the promoter

I GijselinckS Van MosseveldeJ van der ZeeAnne SiebenS EngelborghsJan De BleeckerA IvanoiuO DeryckD EdbauerM Zhang et al.

A1 Journal Article in MOLECULAR PSYCHIATRY

2015

A 22-single nucleotide polymorphism Alzheimer's disease risk score correlates with family history, onset age, and cerebrospinal fluid Aβ42

Kristel SleegersKarolien BettensArne De RoeckCaroline Van CauwenbergheElise CuyversJan VerheijenHanne StruyfsJasper Van DongenSteven VermeulenSebastiaan Engelborghs et al.

A1 Journal Article in ALZHEIMERS & DEMENTIA

Bilingualism delays clinical manifestation of Alzheimer's disease

Evy WoumansPatrick SantensAnne SiebenJan VersijptMichaël StevensWouter Duyck

Bilingualism delays clinical manifestation of Alzheimer's disease

Evy WoumansPatrick SantensAnne SiebenJan VersijptMichaël StevensWouter Duyck

A1 Journal Article in BILINGUALISM-LANGUAGE AND COGNITION

Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains

Jonathan JanssensStephanie PhiltjensGernot KleinbergerSara Van MosseveldeJulie van der ZeeRita CacaceSebastiaan EngelborghsAnne SiebenJulia Banzhaf-StrathmannLubina Dillen et al.

A1 Journal Article in ACTA NEUROPATHOLOGICA COMMUNICATIONS

Loss of TBK1 is a frequent cause of frontotemporal dementia in a Belgian cohort

Ilse GijselinckSara Van MosseveldeJulie van der ZeeAnne SiebenStephanie PhiltjensBavo HeemanSebastiaan EngelborghsMathieu VandenbulckeGreet De BaetsVeerle Baumer et al.

A1 Journal Article in NEUROLOGY

2014

Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia

Elise CuyversKarolien BettensStéphanie PhiltjensTim Van LangenhoveIlse GijselinckJulie van der ZeeSebastiaan EngelborghsMathieu VandenbulckeJasper Van DongenNathalie Geerts et al.

A1 Journal Article in NEUROBIOLOGY OF AGING

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

Julie van der ZeeTim Van LangenhoveGabor G KovacsLubina DillenWilliam DeschampsSebastiaan EngelborghsRadoslav MatějMathieu VandenbulckeAnne SiebenBart Dermaut et al.

A1 Journal Article in ACTA NEUROPATHOLOGICA

2013

A pan-European study of the C9orf72 repeat associated with FTLD : geographic prevalence, genomic instability, and intermediate repeats

Julie van der ZeeIlse GijselinckLubina DillenTim Van LangenhoveJessie TheunsSebastiaan EngelborghsStéphanie PhiltjensMathieu VandenbulckeKristel SleegersAnne Sieben et al.

A1 Journal Article in HUMAN MUTATION

Distinct clinical characteristics of C9orf72 expansion carriers compared with GRN, MAPT, and nonmutation carriers in a Flanders-Belgian FTLD cohort

Tim Van LangenhoveJulie van der ZeeIlse GijselinckSebastiaan EngelborghsRik VandenbergheMathieu VandenbulckeJan De BleeckerAnne SiebenJan VersijptAdrian Ivanoiu et al.

A1 Journal Article in JAMA NEUROLOGY

Explorative genetic study of UBQLN2 and PFN1 in an extended Flanders-Belgian cohort of frontotemporal lobar degeneration patients

Lubina DillenTim Van LangenhoveSebastiaan EngelborghsMathieu VandenbulckeStayko SarafovIvailo TournevCeline MerlinPatrick CrasRik VandenberghePeter P De Deyn et al.

A1 Journal Article in NEUROBIOLOGY OF AGING

2012

A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum : a gene identification study

Ilse GijselinckTim Van LangenhoveJulie van der ZeeKristel SleegersStephanie PhiltjensGernot KleinbergerJonathan JanssensKarolien BettensCaroline Van CauwenbergheSandra Pereson et al.

A1 Journal Article in LANCET NEUROLOGY

Distinct clinical characteristics of C9orf72 expansion carriers compared to GRN, MAPT and non-mutation carries in a Flanders-Belgian FTLD cohort

Tim Van LangenhoveJulie van der ZeeIlse GijselinckSebastiaan EngelborghsRik VandenbergheMathieu VandenbulckeJan De BleeckerAnne SiebenAdrian IvanoiuOliver Deryck et al.

Late-onset post-irradiation vasculopathy of the posterior cerebral vasculature

Jelle van den AmeeleAnne SiebenCaroline Van den BroeckeTom BoterbergLuc DefreyneEric AchtenMartin LammensDimitri Hemelsoet

A1 Journal Article in ACTA NEUROLOGICA BELGICA

Neoplasm related encephalopathies

Lore LapeireAnne SiebenPatrick SantensSimon Van Belle

Bookchapter in Miscellanea on encephalopathies : a second look

The genetics and neuropathology of frontotemporal lobar degeneration

Anne SiebenTim Van LangenhoveSebastiaan EngelborghsJean-Jacques MartinPaul BoonPatrick CrasPeter-Paul De DeynPatrick SantensChristine Van BroeckhovenMarc Cruts

A1 Journal Article in ACTA NEUROPATHOLOGICA

2009

Repetitive transcranial magnetic stimulation in patients with progressive supranuclear palsy : a pilot study

Patrick SantensAnne SiebenMiet De Letter

A1 Journal Article in ACTA NEUROLOGICA BELGICA

2008

Characteristics and outcomes of patients with seizures according to the time of onset in relation to stroke

Jacques De ReuckAnne SiebenGEORGES VAN MAELE

A1 Journal Article in EUROPEAN NEUROLOGY

2007

A massive extradural cerebrospinal fluid collection

Koen PaemeleireAnne SiebenWOUTER BAUTERSDirk Uyttendaele

Editorial material

Preliminary screening results for fabry disease in young stroke patients reveals a new mutation

Dimitri HemelsoetBruce PoppeAnne SiebenFREDERIK VANHEEPASCAL PROOTM De ClerckBart LeroyJulie De BackerBirgit WuytsLJ De Meirleir et al.

Saccadic ping pong gaze in coma

Anne SiebenLuc CrevitsPatrick Santens

A1 Journal Article in NEUROLOGIST

2006

Deep brain stimulation of the internal pallidum in multiple system atrophy

Patrick SantensKristl VonckMiet De LetterKatya Van DriesscheAnne SiebenJacques De ReuckDirk Van RoostPaul Boon

A1 Journal Article in PARKINSONISM & RELATED DISORDERS

2004

Tic reduction in Tourette's disorder with olanzapine

K NaudtsK DhondtAnne SiebenFREDERIQUE VAN DEN EYNDEKurt AudenaertCornelis Van Heeringen