Research Explorer

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Researcher

Anna Kuchmiy

Publications & Research Data

Awards & Distinctions

27 Results

2022

Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development

Juliette RoelsJolien Van HulleMarieke LavaertAnna KuchmiySteven StrubbeTom PuttemanBart VandekerckhoveGeorges LeclercqFilip Van NieuwerburghLena Boehme et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2021

A tumor suppressor enhancer of PTEN in T-cell development and leukemia

L TottoneO LanchoJW LohA SinghS KimuraJuliette RoelsAnna KuchmiySteven StrubbeMA LawlorV da Silva-Diz et al.

A2 Journal Article in BLOOD CANCER DISCOVERY

2020

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

Juliette RoelsMorgan ThénozBronislawa SzarzynskaMattias LandforsStien De ConinckLisa DemoenLien ProvezAnna KuchmiySteven StrubbeLindy Reunes et al.

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

Juliette RoelsMorgan ThénozB SzarzyńskaM LandforsStien De ConinckLisa DemoenLien ProvezAnna KuchmiySteven StrubbeLindy Reunes et al.

A2 Journal Article in BLOOD CANCER DISCOVERY

Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development

Juliette RoelsAnna KuchmiyMatthias De DeckerSteven StrubbeMarieke LavaertKai Ling LiangGeorges LeclercqBart VandekerckhoveFilip Van NieuwerburghPieter Van Vlierberghe et al.

A1 Journal Article in NATURE IMMUNOLOGY

hsa-miR-20b-5p and hsa-miR-363-3p affect expression of PTEN and BIM tumor suppressor genes and modulate survival of T-ALL cells in vitro

Monika DrobnaBronisława SzarzyńskaRoman JaksikŁukasz SędekAnna KuchmiyTom TaghonPieter Van VlierbergheTomasz SzczepańskiMichał WittMałgorzata Dawidowska

A1 Journal Article in CELLS

Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia

Yalu ZhouCuijuan HanEric WangAdam H. LorchValentina SerafinByoung-Kyu ChoBlanca T. Guttierrez DiazJulien CalvoCelestia FangAlireza Khodadadi-Jamayran et al.

A1 Journal Article in CANCER DISCOVERY

2018

SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival

Hexiu SuJuncheng HuLiang HuangYang YangMorgan ThénozAnna KuchmiyYufeng HuPeng LiHui FengYu Zhou et al.

A1 Journal Article in NATURE COMMUNICATIONS

2017

Highly variable frequencies of donor antigen-specific naive cells may dictate the immunogenicity of minor histocompatibility antigens after hematopoietic stem cell transplantation

Anna KuchmiySavely SheetikovDmitrii RomaniukAnna PostovskayaSergey FilkinNadia BykovaGrigory EfimovValeriy G. Savchenko

Immunogenicity of minor histocompatibility antigens may be dependent on the frequencies of naive precursor cells in the donor repertoire

Anna KuchmiySavely SheetikovDmitrii RomaniukAnna PostovskayaSergey FilkinNadezhda BykovaGrigory Efimov

PD-1 is highly expressed on memory T-cell subsets residing in bone marrow but not in peripheral blood in healthy individuals

N PopovaM DrokovAnna KuchmiyA VdovinJ DavydovaL KuzminaD DubnyakE MikhalcovaV VasilyevaO Koroleva et al.

2016

Inactivation of inflammasomes by pathogens regulates inflammation

FYu GaribAP RizopuluAnna KuchmiyVF Garib

A1 Journal Article in BIOCHEMISTRY-MOSCOW

NLRP2 controls age-associated maternal fertility

Anna KuchmiyJinke D'HontTino HochepiedMohamed Lamkanfi

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

NOD-like receptor Nlrp2 is dispensable for immune signaling, but critical for efficient early embryonic development in aged oocytes

Anna KuchmiyJinke D’HontTino HochepiedMohamed Lamkanfi

2014

Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulfate-induced colitis

Dieter DemonAnna KuchmiyAmelie FossoulQ ZhuT-D KannegantiMohamed Lamkanfi

A1 Journal Article in MUCOSAL IMMUNOLOGY

Clusterin is a potential lymphotoxin beta receptor target that is upregulated and accumulates in germinal centers of mouse spleen during immune response

Marina A. AfanasyevaLiudmila V. BritanovaKirill V. KorneevNikita A. MitkinAnna KuchmiyDmitry V Kuprash

A1 Journal Article in PLOS ONE

Experimental applications of TNF-reporter mice with far-red fluorescent label

Yury V ShebzukhovAnna KuchmiyAndrei A KruglovFrauke ZippVolker SiffrinSergei A Nedospasov

Bookchapter in The TNF superfamily : methods and protocols

Inflammasomes in respiratory disease: from bench to bedside

Guy BrusselleSharen ProvoostKen BrackeAnna KuchmiyMohamed Lamkanfi

A1 Journal Article in CHEST

NOD-like receptors interfacing the immune and reproductive systems

Hanne Van GorpAnna KuchmiyFilip Van HauwermeirenMohamed Lamkanfi

A1 Journal Article in FEBS JOURNAL

2013

Dynamic changes in chromatin conformation at the TNF transcription start site in T helper lymphocyte subsets

Yury V ShebzukhovKatharina HornKristina I BrazhnikMarina S DrutskayaAnna KuchmiyDmitry V KuprashSergei A Nedospasov

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

2012

Analysis of a novel 8.9kb cryptic plasmid from Bacteroides uniformis, its long-term stability and spread within human microbiota

Andrei N ShkoporovEkaterina V KhokhlovaElena V KulaginaVladimir V SmeianovAnna KuchmiyLyudmila I KafarskayaBoris A Efimov

A1 Journal Article in PLASMID

Methods for in vivo molecular imaging

Anna KuchmiyGA EfimovSA Nedospasov

A1 Journal Article in BIOCHEMISTRY-MOSCOW

2011

Modalities of experimental TNF blockade in vivo : mouse models

AA KruglovAV TumanovSI GrivennikovYuV ShebzukhovAnna KuchmiyGA EfimovMS DrutskayaJ SchellerDV KuprashSergei A Nedospasov

A1 Journal Article in Advances in Experimental Medicine and Biology

New TNF reporter mouse with red fluorescent protein Katushka

Anna KuchmiyAA KruglovDV KuprashDM ChudakovSA LukyanovSA Nedospasov

2009

Accelerated thymic atrophy as a result of elevated homeostatic expression of the genes encoded by the TNF/lymphotoxin cytokine locus

Dmitry J LiepinshAndrei A KruglovArthur R GalimovAlexander N ShakhovYuriy V ShebzukhovAnna KuchmiySergei I GrivennikovAlexei V TumanovMarina S DrutskayaLionel Feigenbaum et al.

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

2008

Mice in which human TNF is mediating both beneficial and deleterious functions : a model comparison of different blockade strategies

AA KruglovYuV ShebzukhovAnna KuchmiyAR GalimovG EfimovSI GrivennikovDV KuprashSV KozlovSA Nedospasov

Physiological functions of tumor necrosis factor and the consequences of its pathologic overexpression or blockade : mouse models

Andrei A KruglovAnna KuchmiySergei I GrivennikovAlexei V TumanovDmitry V KuprashSergei A Nedospasov

A1 Journal Article in CYTOKINE & GROWTH FACTOR REVIEWS