Research Explorer

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Researcher

Ann Osselaere

Awards & Distinctions

29 Results

2013

Characterization of in vitro intestinal absorption of veterinary drugs and coccidiostats in the presence of mycotoxin detoxifiers using a porcine intestinal epithelial cell line: outline of the study

Thomas De MilMathias DevreeseAnn OsselaereElin VerbruggheJoline GoossensFrank PasmansPatrick De BackerSiska Croubels

Chronic exposure to the mycotoxin T-2 promotes oral absorption of chlortetracycline in pigs

Joline GoossensMathias DevreeseFrank PasmansAnn OsselaereSiegrid De BaereElin VerbruggheFreddy HaesebrouckPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Chronic exposure to the mycotoxin deoxynivalenol affects the intestinal barrier function in broilers

Gunther AntonissenFilip Van ImmerseelFrank PasmansRichard DucatelleFreddy HaesebrouckAnn OsselaereLeen TimbermontMarc VerlindenMia EeckhoutEvelyne Delezie et al.

Deoxynivalenol impairs hepatic and intestinal gene expression of selected oxidative stress, tight junction and inflammation proteins in broiler chickens, but addition of an adsorbing agent shifts the effects to the distal parts of the small intestine

Ann OsselaereRegiane SantosVeerle HautekietPatrick De BackerKoen ChiersRichard DucatelleSiska Croubels

A1 Journal Article in PLOS ONE

Development and validation of an LC-MS/MS method for the determination of DON, 3A-DON and 15A-DON in chicken plasma

Nathan BroekaertMathias DevreeseThomas De MilAnn OsselaereSophie FraeymanSarah De SaegerSiska Croubels

Hepatic and intestinal CYP3A expression and activity in broilers

Ann OsselaereLies De BockVenessa EeckhautPatrick De BackerJan Van BocxlaerKoen BousserySiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Influence of deoxynivalenol and T-2 toxin on the intestinal barrier and liver function in broiler chickens

Ann OsselaereSiska CroubelsPatrick De Backer

Quantitative determination of the Fusarium mycotoxins beauvericin, enniatin A, A1, B and B1 in pig plasma using high performance liquid chromatography-tandem mass spectrometry

Mathias DevreeseSiegrid De BaereAnn OsselaereThomas De MilNathan BroekaertPatrick De BackerSiska Croubels

The mycotoxin T-2 inhibits hepatic cytochrome P4503A activity in pigs

Joline GoossensLies De BockAnn OsselaereElin VerbruggheMathias DevreeseKoen BousseryJan Van BocxlaerPatrick De BackerSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Toxic effects of dietary exposure to T-2 toxin on intestinal and hepatic biotransformation enzymes and drug transporter systems in broiler chickens

Ann OsselaereShaoji LiLies De BockMathias DevreeseJoline GoossensVirginie VandenbrouckeJan Van BocxlaerKoen BousseryFrank PasmansAn Martel et al.

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Toxicokinetic study and absolute oral bioavailability of deoxynivalenol, T-2 toxin and zearalenone in broiler chickens

Ann OsselaereMathias DevreeseJoline GoossensVirginie VandenbrouckeSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

2012

Development of a liquid-chromatography tandem mass spectrometry and ultra-high-performance liquid chromatography high-resolution mass spectrometry method for the quantitative determination of zearalenone and its major metabolites in chicken and pig plasma

Siegrid De BaereAnn OsselaereMathias DevreeseLynn VanhaeckePatrick De BackerSiska Croubels

A1 Journal Article in ANALYTICA CHIMICA ACTA

Effect of T-2 toxin and a yeast-extract feed additive on the oral bioavailability of chlortetracycline in pigs

Joline GoossensFrank PasmansVirginie VandenbrouckeElin VerbruggheMathias DevreeseAnn OsselaereSiegrid De BaereFreddy HaesebrouckPatrick De BackerSiska Croubels

Efficacy and safety testing of mycotocoxin-detoxifying agents in broilers following the European Food Safety Authority guidelines

Ann OsselaereMathias DevreeseAnneleen WatteynVirginie VandenbrouckeJoline GoossensVeerle HautekietMia EeckhoutSarah De SaegerSiegrid De BaerePatrick De Backer et al.

A1 Journal Article in POULTRY SCIENCE

In vitro and in vivo safety testing of mycotoxin detoxifying agents

Mathias DevreeseJoline GoossensAnn OsselaereVirginie VandenbrouckeSiegrid De BaerePatrick De BackerSiska Croubels

Influence of mycotoxins and a mycotoxin adsorbing agent on the oral bioavailability of commonly used antibiotics in pigs

Joline GoossensVirginie VandenbrouckeFrank PasmansSiegrid De BaereMathias DevreeseAnn OsselaereElin VerbruggheFreddy HaesebrouckSarah De SaegerMia Eeckhout et al.

A1 Journal Article in TOXINS

Interaction between tylosin and bentonite clay from a pharmacokinetic perspective

Mathias DevreeseAnn OsselaereJoline GoossensVirginie VandenbrouckeSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in VETERINARY JOURNAL

Interaction between tylosin and bentonite clay from a pharmacokinetic perspective

Mathias DevreeseAnn OsselaereJoline GoossensSiegrid De BaerePatrick De BackerSiska Croubels

New bolus models for in vivo efficacy testing of mycotoxin detoxifying agents in relation to EFSA guidelines, assessed using deoxynivalenol in broiler chickens

Mathias DevreeseAnn OsselaereJoline GoossensVirginie VandenbrouckeSiegrid De BaereMia EeckhoutPatrick De BackerSiska Croubels

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

Quantitative determination of zearalenone and its major metabolites in animal plasma using LC-MS/MS and (U)HPLC-HR-MS detection

Siegrid De BaereAnn OsselaereMathias DevreesePatrick De BackerSiska Croubels

Toxic effects of dietary exposure to T-2 toxin on intestinal and hepatic CYP450 in broilers

Ann OsselaereShaoji LiLies De BockMathias DevreeseJoline GoossensVirginie VandenbrouckeFrank PasmansAn MartelPatrick De BackerSiska Croubels

Toxicokinetic study of deoxynivalenol, T-2 toxin and zearalenone in broiler chickens

Ann OsselaereMathias DevreeseJoline GoossensVirginie VandenbrouckeSiegrid De BaerePatrick De BackerSiska Croubels

2011

Efficacy and safety testing of mycotoxin-detoxifying agents in broilers following the EFSA guidelines

Ann OsselaereAnneleen WatteynSiegrid De BaereSarah De SaegerMia EeckhoutPatrick De BackerSiska Croubels

In vivo efficacy testing of mycoxotoxin binders in poultry by means of a toxicokinetic study according to EFSA guidelines

Mathias DevreeseAnn OsselaereSiegrid De BaerePatrick De BackerSiska Croubels

Influence of mycotoxin detoxifying agents on the plasma pharmacokinetics and tissue residues of amoxicillin and oxytetracycline in poultry

Ann OsselaereJoline GoossensSiegrid De BaereSarah De SaegerMia EeckhoutPatrick De BackerSiska Croubels

Nieuwe Europese (EFSA) richtlijnen om de efficaciteit van mycotoxine binders en modifiers aan te tonen

Mathias DevreeseAnn OsselaereJoline GoossensSiegrid De BaerePatrick De BackerSiska Croubels

Quantitative determination of T-2 toxin, HT-2 toxin, deoxynivalenol and deepoxy-deoxynivalenol in animal body fluids using LC-MS/MS detection

Siegrid De BaereJoline GoossensAnn OsselaereMathias DevreeseVirginie VandenbrouckePatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

2010

Development of a quantitative method for the determination of Fusarium mycotoxins in pig plasma using liquid chromatography tandem mass spectrometry

Siegrid De BaereJoline GoossensVirginie VandenbrouckeAnn OsselaerePatrick De BackerSiska Croubels

Quantitative determination of deoxynivalenol and related compounds in animal plasma using LC-MS/MS as part of a toxicokinetic study

Siegrid De BaereAnn OsselaereMathias DevreeseJoline GoossensVirginie VandenbrouckePatrick De BackerSiska Croubels