Research Explorer

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Researcher

Anja Geerts

Publications & Research Data

Awards & Distinctions

314 Results

2025

A larger decline of IgG after initiation of treatment in patients with AIH is associated with complete biochemical response despite having normal baseline IgG levels

Lorenz GrossarSarah RaevensAnja GeertsChristophe Van SteenkisteIsabelle ColleCharlotte De VlooHans OrlentJeoffrey SchoutenMarie GallantAnnelien Van Driessche et al.

A repository of the salivary metabolome and its key drivers in 1436 European children

Ellen De PaepeEmile CallemeynKimberly De WindtKathleen WijnantVera PlekhovaBeata PomianPablo VangeenderhuysenStefaan De HenauwNathalie MichelsHeli Viljakainen et al.

A1 Journal Article in EBIOMEDICINE

Co-existing regeneration mechanisms in severe alcohol-related steatohepatitis

Adrienne LejeunePeter StaerkelAlexandre LouvetAxel HitteletCeline BazilleBoris BastensHans OrlentLuc LasserXavier DekoninckSergio Negrin Dastis et al.

A2 Journal Article in TRANSLATIONAL GASTROENTEROLOGY AND HEPATOLOGY

Development and validation of pFIB scores for exclusion of significant liver fibrosis in pediatric MASLD

Sander LefereAntonella MoscaChristian HudertEllen DupontEmer FitzpatrickEirini KyranaAnil DhawanLaura KalveramAndrea PietrobattistaAnja Geerts et al.

A1 Journal Article in HEPATOLOGY

Diastolic dysfunction : prevalence and outcome in liver transplantation candidates

Francis VoetMaxim KhalenkowMichel De PauwXavier VerhelstSander LefereAnja GeertsHans Van VlierbergheSarah Raevens

A1 Journal Article in ANNALS OF HEPATOLOGY

Early plasmapheresis in type 2 benign recurrent intrahepatic cholestasis : a case report and review of literature

Lander HeyerickAnnemieke DhondtHans Van VlierbergheXavier VerhelstSarah RaevensAnja Geerts

A2 Journal Article in WORLD JOURNAL OF HEPATOLOGY

Exploring the salivary metabolome : key drivers and insights from 1,436 European children

Emile CallemeynEllen De PaepeLynn VanhaeckeVera PlekhovaKimberly De WindtMatthijs VynckPablo VangeenderhuysenNathalie MichelsAnja Geerts

Glycomics as prognostic biomarkers of hepatocellular carcinoma : a systematic review

Nicky SomersEmma ButayeLorenz GrossarNele PauwelsAnja GeertsSarah RaevensSander LefereLindsey DevisscherLeander MeurisNico Callewaert et al.

A1 Journal Article in ONCOLOGY LETTERS

Harnessing human immune system mouse models to validate NADPH oxidase 1 inhibition as a treatment for hepatocellular carcinoma

Zenzi De VosLander HeyerickHannah StocksAndy WullaertAnne HoorensSander LefereSarah RaevensAnja GeertsXavier VerhelstHans Van Vlierberghe et al.

Mitochondrial dysfunction characterises the multigenerational effects of maternal obesity on MASLD

Anneleen HeldensMilton Boaheng AntwiLouis OnghenaTim MeeseYannick GansemansJoél SmetEllen DupontXavier VerhelstSarah RaevensHans Van Vlierberghe et al.

A1 Journal Article in JHEP REPORTS

Pathophysiology and complications of metabolic dysfunction-associated steatotic liver disease

Anneleen HeldensAnja GeertsRuth De BruyneSander Lefere

PPARα-ERRα crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression

Milton Boaheng AntwiSander LefereDorien ClarisseLisa KoorneefAnneleen HeldensLouis OnghenaKylian DecroixDaria FijalkowskaJonathan ThommisMadeleine Hellemans et al.

A1 Journal Article in METABOLISM-CLINICAL AND EXPERIMENTAL

Reassessing the prevalence of portopulmonary hypertension : insights from a prospective study in cirrhotic patients

Andreas MeertElise WulfranckeAnja GeertsXavier VerhelstEls VandecasteeleHans Van VlierbergheMichel De PauwSarah Raevens

A1 Journal Article in MAYO CLINIC PROCEEDINGS

Reply : can pFIB scores reliably exclude significant liver fibrosis in pediatric MASLD?

Sander LefereAntonella MoscaChristian HudertEllen DupontEmer FitzpatrickEirini KyranaAnil DhawanLaura KalveramAndrea PietrobattistaAnja Geerts et al.

A1 Journal Article in HEPATOLOGY

Reply : development and validation of pFIB scores for exclusion of significant liver fibrosis in pediatric MASLD

Sander LefereAntonella MoscaChristian HudertEllen DupontEmer FitzpatrickEirini KyranaAnil DhawanLaura KalveramAndrea PietrobattistaAnja Geerts et al.

A1 Journal Article in HEPATOLOGY

Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease : lessons from animal studies

Wouter ClaeysAnja GeertsLien Van HoeckeChristophe Van SteenkisteRoosmarijn Vandenbroucke

A1 Journal Article in NEURAL REGENERATION RESEARCH

The association of ultra‐processed food intake with adolescent metabolic dysfunction‐associated steatotic liver disease in the NHANES

Maarten BuytaertDimitri DeclercqFleur DepoorterZerlina CosijnLindsey DevisscherSarah RaevensXavier VerhelstHans Van VlierbergheAnja GeertsRuth De Bruyne et al.

A1 Journal Article in PEDIATRIC OBESITY

The burden of ascites in cirrhosis

Jeanne BekaertM. AertsS. FrancoisSarah RaevensHelena DegrooteAnja GeertsXavier VerhelstHans Van VlierbergheH. Reynaert

A1 Journal Article in ACTA CLINICA BELGICA

The clinical relevance of prior metabolic and bariatric surgery in alcohol-related liver disease in a nationwide Belgian liver transplant population

Sander LefereRoberto Ivan TroisiVincent KaramConstantino FondevilaFrederik NevensJef VerbeekOlivier DetryNicolas LanthierMatteo SerenariLeke Wiering et al.

A1 Journal Article in LIVER INTERNATIONAL

The double-edged sword of metabolic and bariatric surgery : extending the biliary limb can trigger bacterial translocation, sepsis, and liver inflammation : an experimental study

Louis OnghenaAnneleen HeldensKim De PaepeMilton Boaheng AntwiHans Van VlierbergheSarah RaevensXavier VerhelstAnne HoorensLindsey DevisscherYves Van Nieuwenhove et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF SURGERY

The pan-PPAR agonist lanifibranor reduces portal pressure independent of fibrosis reduction through the splanchnic vasculature

Anneleen HeldensChristophe CasteleynLouis OnghenaMilton Boaheng AntwiSara NeytBenedicte DescampsChristian VanhoveXavier VerhelstSarah RaevensHans Van Vlierberghe et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

The pediatric salivary metabolome : non-invasive insights into key drivers across 1,436 children

Emile CallemeynEllen De PaepeKimberly De WindtVera PlekhovaPablo VangeenderhuysenNathalie MichelsAnja GeertsMatthijs VynckLynn Vanhaecke

Therapeutic plasma exchange improves outcomes in Amanita phalloides induced acute liver failure-results from an interim analysis of the Amanita-PEX study

Klaus StahlBahar NalbantAlejandro Campos MurguiaHeiner WedemeyerIsaure BreteauEric LevesqueValentin CoirierFlorent ArtruHugo Pinto MarquesFilipe Sousa Cardoso et al.

2024

Adipose tissue insulin resistance correlates with disease severity in pediatric metabolic dysfunction-associated steatotic liver disease : a prospective cohort study

Anneleen HeldensEllen DupontLindsey DevisscherMaarten BuytaertXavier VerhelstSarah RaevensHans Van VlierbergheAnja GeertsRuth De BruyneSander Lefere

A1 Journal Article in JOURNAL OF PEDIATRICS

Bariatric surgery is a major independent factor of disease progression in cirrhotic patients with alcohol-related liver disease

Louis OnghenaLindsey DevisscherHans Van VlierbergheSarah RaevensXavier VerhelstYves Van NieuwenhoveSander LefereAnja Geerts

Bariatric surgery post-liver transplantation : a Belgian nationwide study

Louis OnghenaAnja GeertsFrederik BerrevoetJacques PirenneJef VerbeekEliano Bonaccorsi-RianiGeraldine DahlqvistLuisa VonghiaOlivier DetryJean Delwaide et al.

A1 Journal Article in LIVER TRANSPLANTATION

Determining the drivers of pediatric overweight and obesity : how does the salivary metabolome reflect children’s anthropometrics and dietary intake?

Emile CallemeynEllen De PaepePablo VangeenderhuysenNathalie MichelsStefaan De HenauwAnja GeertsLynn Vanhaecke

Evolution of health-related quality of life in liver transplantation patients in relation to acceptance and metabolic liver disease

Janne SuykensLouis OnghenaFrederik BerrevoetHans Van VlierbergheXavier VerhelstSarah RaevensEric HosteSander LefereAnja GeertsProf dr Carine Poppe

External validation of the IAIHG autoimmune hepatitis response criteria in a multicentric real-world cohort

Lorenz GrossarSarah RaevensChristophe Van SteenkisteIsabelle ColleCharlotte De VlooHans OrlentJeoffrey SchoutenMarie GallantAnnelien Van DriesscheSander Lefere et al.

A1 Journal Article in JHEP REPORTS

External validation of the international autoimmune hepatitis group response criteria in a multicentric real-world cohort

Lorenz GrossarSarah RaevensChristophe Van SteenkisteIsabelle ColleCharlotte De VlooHans OrlentJeoffrey SchoutenMarie GallantAnnelien Van DriesscheSander Lefere et al.

Fatal acute pulmonary embolism following endoscopic cyanoacrylate injection for gastric fundal varices

Charlotte HarthP. De MulderSarah RaevensKymentie FerdinandePieter HindryckxAnja GeertsHans Van VlierberghePeter VanlangenhoveXavier Verhelst

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

NADPH oxidase 1 inhibition as therapeutic strategy in hepatocellular carcinoma : insights from human-relevant models

Zenzi De VosLander HeyerickLUIS ABREU DE CARVALHOHasan EkerFilip GryspeerdtFrederik BerrevoetSander LefereAnja GeertsSarah RaevensXavier Verhelst et al.

Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis

Kevin De MuynckLander HeyerickFederico Francesco De PontiBart VanderborghtTim MeeseSanne Van CampenhoutLeen BaudonckEva GijbelsPedro M. RodriguesJesus M. Banales et al.

A1 Journal Article in HEPATOLOGY

Pre-treatment serum N-glycans predict poor immunotherapy response and survival in hepatocellular carcinoma

Nicky SomersTheresa HoltmannFabian ArtusaEmma ButayeLorenz GrossarSarah RaevensAnja GeertsSander LefereLindsey DevisscherLeander Meuris et al.

Prior metabolic and bariatric surgery is an independent determinant of severity of decompensation in alcohol-associated liver disease

Louis OnghenaYves Van NieuwenhoveHans Van VlierbergheLindsey DevisscherSarah RaevensXavier VerhelstSander LefereAnja Geerts

A1 Journal Article in UNITED EUROPEAN GASTROENTEROLOGY JOURNAL

Recurrent rejections after liver transplantation for hepatocellular carcinoma with stem cell features in an adult patient

Simon MeganckSarah RaevensKymentie FerdinandeXavier VerhelstAnne HoorensHelena DegrooteAnja GeertsHans Van Vlierberghe

A1 Journal Article in ACTA CLINICA BELGICA

Specific glycomic profiles can identify patients at risk of poor transplant-free survival in primary biliary cholangitis

Nicky SomersNikolaos GatselisMaria C. van HooffVasiliki LygouraEmma ButayeLorenz GrossarSarah RaevensAnja GeertsSander LefereLindsey Devisscher et al.

Structured peer-support for people with rare diseases on the example of the international project Q.RARE.LI

Natalie UhlenbuschArpinder BalBoglarka BalogAnnika BraunAnja GeertsGideon HirschfieldMaciej JanikAnsgar LohsePiotr MilkiewiczMaria Papp et al.

Systematic review : glycomics as diagnostic markers for hepatocellular carcinoma

Emma ButayeNicky SomersLorenz GrossarNele PauwelsSander LefereLindsey DevisscherSarah RaevensAnja GeertsLeander MeurisNico Callewaert et al.

A1 Journal Article in ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The double-edged sword of bariatric surgery : extending the excluded limb can trigger bacterial translocation, liver inflammation and death

Louis OnghenaAnneleen HeldensMilton Boaheng AntwiLindsey DevisscherHans Van VlierbergheSarah RaevensXavier VerhelstAnne HoorensYves Van NieuwenhoveAnja Geerts et al.

The role of interleukin-8 in primary sclerosing cholangitis-associated immune cell dysregulation

Lander HeyerickKevin De MuynckZenzi De VosSander LefereJana RoelsNiels VandammeAnja GeertsSarah RaevensXavier VerhelstHans Van Vlierberghe et al.

Therapeutic plasma exchange in Amatoxin associated acute liver failure-results from an interim analysis of the Amanita-PEX study

Klaus StahlBahar NalbantTobias LaueFilipe Sousa CardosoJoao MadalenoPetra StoeckertDaniel TegtmeyerAngelo Di GiorgioKarsten GrosseUta Merle et al.

Transgenerational maternal obesity induces mitochondrial dysfunction and aggravates MASLD, which can be reversed by metabolic drug candidates

Anneleen HeldensMilton Boaheng AntwiLouis OnghenaLindsey DevisscherXavier VerhelstSarah RaevensHans Van VlierbergheRuth De BruyneAnja GeertsSander Lefere

Ultra-processed food intake does not correlate with pediatric MASLD in the National Health and Nutrition Examination Survey

Maarten BuytaertDimitri DeclercqFleur DepoorterZerlina CosijnLindsey DevisscherAnja GeertsXavier VerhelstHans Van VlierbergheSarah RaevensRuth De Bruyne et al.

Unlocking therapeutic potential : exploring cross-talk among emerging nuclear receptors to combat metabolic dysfunction in steatotic liver disease

Milton Boaheng AntwiAriann JenningsSander LefereDorien ClarisseAnja GeertsLindsey DevisscherKarolien De Bosscher

A2 Journal Article in NPJ METABOLIC HEALTH AND DISEASE

Unravelling the coagulation paradox in liver cirrhosis : challenges and insights

Kymentie FerdinandeSarah RaevensJ. DecaesteckerC. De VlooL. SeynhaeveLore HoofXavier VerhelstAnja GeertsKatrien DevreeseH. Degroote et al.

A1 Journal Article in ACTA CLINICA BELGICA

2023

A remarkable presentation of a massive Budd-Chiari syndrome

Kymentie FerdinandeHelena DegrooteAnja GeertsHans Van VlierbergheXavier VerhelstSarah Raevens

Editorial material

An unusual cause of portal hypertension

Kymentie FerdinandeThibaud LamiroyAnne HoorensXavier VerhelstHelena DegrooteSarah RaevensHans Van VlierbergheAnja Geerts

Editorial material

Application of updated diagnostic criteria for cirrhotic cardiomyopathy : evaluation of its clinical impact in liver transplantation candidates

Maxim KhalenkowFrancis VoetMichel De PauwSander LefereHelena DegrooteXavier VerhelstAnja GeertsHans Van VlierbergheSarah Raevens

Bariatric surgery for NAFLD : indications and post-operative management

Anja GeertsSander Lefere

A1 Journal Article in CLINICAL AND MOLECULAR HEPATOLOGY

Experimental hepatic encephalopathy causes early but sustained glial transcriptional changes

Wouter ClaeysLien Van HoeckeHannah LernoutClint De NolfGriet Van ImschootElien Van WonterghemDaan VerhaegeJonas CasteleinAnja GeertsChristophe Van Steenkiste et al.

A1 Journal Article in JOURNAL OF NEUROINFLAMMATION

FibroScan-aspartate aminotransferase (FAST) score for monitoring histological improvement in non-alcoholic steatohepatitis activity during semaglutide treatment : post-hoc analysis of a randomised, double-blind, placebo-controlled, phase 2b trial

Vincent Wai-Sun WongQuentin M. AnsteeLouise M. NitzeAnja GeertsJacob GeorgeVictor NolascoMette S. KjaerSteen LadelundPhilip N. NewsomeVlad Ratziu

A1 Journal Article in ECLINICALMEDICINE

Glycomics-based serum markers as reliable tool for assessment of viral response after treatment with direct-acting antiviral drugs in hepatitis C virus infection

Nicky SomersElisabeth VandekerckhoveAnja GeertsHelena DegrooteSander LefereLindsey DevisscherLeander MeurisNico CallewaertHans Van VlierbergheXavier Verhelst

A1 Journal Article in ACTA CLINICA BELGICA

Hepatic safety and efficacy of immunomodulatory drugs used in patients with autoimmune hepatitis

Benedetta Terziroli Beretta-PiccoliGustav BuescherGeorge DalekosKalliopi ZachouAnja GeertsNasser SemmoMirjam KolevEleonora De MartinMaciej K. JanikJoao Madaleno et al.

A1 Journal Article in JOURNAL OF AUTOIMMUNITY

Intensive lifestyle management improves steatosis and fibrosis in pediatric nonalcoholic fatty liver disease : reply

Sander LefereAnja GeertsRuth De Bruyne

A1 Journal Article in CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

Kupffer cells contested as early drivers in the pathogenesis of primary sclerosing cholangitis

Kevin De MuynckBart VanderborghtFederico Francesco De PontiEva GijbelsSophie Van WeldenMartin GuilliamsCharlotte ScottAlain BeschinMathieu VinkenSander Lefere et al.

A1 Journal Article in AMERICAN JOURNAL OF PATHOLOGY

Limitations of PLX3397 as a microglial investigational tool : peripheral and off-target effects dictate the response to inflammation

Wouter ClaeysDaan VerhaegeGriet Van ImschootElien Van WonterghemLore Van AckerLaura AmelinckFederico Francesco De PontiCharlotte ScottAnja GeertsChristophe Van Steenkiste et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Meta-analysis : the impact of light-to-moderate alcohol consumption on progressive non-alcoholic fatty liver disease

Louise MaghermanRobbe Van ParysNele PauwelsXavier VerhelstLindsey DevisscherHans Van VlierbergheAnja GeertsSander Lefere

A1 Journal Article in ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Novel a-1,3-glucosyltransferase variants and their broad clinical polycystic liver disease spectrum

Melissa M. BoerrigterRene H. M. te MorscheHanka VenselaarNikki PastoorsAnja GeertsAnne HoorensJoost P. H. Drenth

A1 Journal Article in GENES

Novel bariatric surgery models in mice-differential effects on body weight loss and fatty liver disease

Louis OnghenaAnneleen HeldensMilton Boaheng AntwiHans Van VlierbergheXavier VerhelstLindsey DevisscherYves Van NieuwenhoveAnja GeertsSander Lefere

Novel pathogenic ALG8 variants and evidence for somatic loss of heterozygosity in 542 autosomal dominant polycystic liver disease patients

Melissa M. BoerrigterRene H. M. te MorscheAnja GeertsAnne HoorensJ. P. H. Drenth

Overview of liver organ allocation policies in Europe and the impact on outcome after liver transplantation

Chloë CallantHelena DegrooteSarah RaevensAnja GeertsE. HosteFrederik BerrevoetLuc ColenbieHans Van VlierbergheXavier Verhelst

Patients hospitalized with alcohol-related liver disease and prior bariatric surgery are more prone to develop acute-on-chronic liver failure

Louis OnghenaYves Van NieuwenhoveLaurissa DemeulenaereLindsey DevisscherXavier VerhelstHelena DegrooteSarah RaevensHans Van VlierbergheSander LefereAnja Geerts

A1 Journal Article in LIVER INTERNATIONAL

Studying microglia and astrocytes in the liver-brain axis during chronic experimental hepatic encephalopathy

Wouter ClaeysRoosmarijn VandenbrouckeChristophe Van SteenkisteAnja Geerts

The pan-PPAR agonist lanifibranor decreases portal pressure in models of both hepatic and prehepatic portal hypertension

Anneleen HeldensChristophe CasteleynLouis OnghenaMilton Boaheng AntwiBenedicte DescampsChristian VanhoveXavier VerhelstHans Van VlierbergheLindsey DevisscherJean-Louis Junien et al.

Transient Kupffer cell depletion and subsequent replacement by infiltrating monocyte-derived cells does not alter the induction or progression of hepatocellular carcinoma

Bart VanderborghtKevin De MuynckEva GijbelsSander LefereCharlotte ScottMartin GuilliamsAlain BeschinMathieu VinkenXavier VerhelstAnja Geerts et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

2022

A mouse model of hepatic encephalopathy : bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation.

Wouter ClaeysLien Van HoeckeAnja GeertsHans Van VlierbergheSander LefereGriet Van ImschootElien Van WonterghemBart GhesquièreRoosmarijn VandenbrouckeChristophe Van Steenkiste

A1 Journal Article in SCIENTIFIC REPORTS

Adipose tissue insulin resistance is a determinant of disease severity in pediatric nonalcoholic fatty liver disease

Anneleen HeldensEllen DupontLindsey DevisscherAnja GeertsRuth De BruyneXavier VerhelstHans Van VlierbergheSander Lefere

Combined therapy with a CCR2/CCR5 antagonist and FGF21 analogue synergizes in ameliorating steatohepatitis and fibrosis

Tobias PuengelSander LefereJana HundertmarkMarlene KohlheppChristian PennersFrederique Van de VeldeBruno LapauwAnne HoorensLindsey DevisscherAnja Geerts et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Different models to predict the risk of recurrent hepatocellular carcinoma in the setting of liver transplantation

Helena DegrooteAnja GeertsXavier VerhelstHans Van Vlierberghe

A1 Journal Article in CANCERS

Glycomics-based serum marker as reliable tool for assessment of viral response after treatment with direct-acting antiviral drugs in hepatitis C virus infection

Nicky SomersElisabeth VandekerckhoveAnja GeertsHelena DegrooteSander LefereLindsey DevisscherLeander MeurisNico CallewaertHans Van VlierbergheXavier Verhelst

Intensive lifestyle management improves steatosis and fibrosis in pediatric non-alcoholic fatty liver disease

Sander LefereEllen DupontAnn De GuchtenaereStephanie Van BiervlietSaskia Vande VeldeXavier VerhelstLindsey DevisscherHans Van VlierbergheAnja GeertsRuth De Bruyne

A1 Journal Article in CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

Maternal and perinatal risk factors for pediatric nonalcoholic fatty liver disease : a systematic review

Ilya QuerterNele PauwelsRuth De BruyneEllen DupontXavier VerhelstLindsey DevisscherHans Van VlierbergheAnja GeertsSander Lefere

A1 Journal Article in CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

Metallothioneins alter macrophage phenotype and represent novel therapeutic targets for acetaminophen-induced liver injury

Lindsey DevisscherSanne Van CampenhoutSander LefereSarah RaevensLaurentijn TillemanFilip Van NieuwerburghHannelore P. Van EeckhoutteAnne HoorensMichael A. LynesAnja Geerts et al.

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

Neurometabolic and gliovascular changes in murine hepatic encephalopathy

Wouter ClaeysLien Van HoeckeAnja GeertsHans Van VlierbergheXavier VerhelstSander LefereHelena DegrooteGriet Van ImschootElien Van WonterghemRoosmarijn Vandenbroucke et al.

Perinatal risk factors for pediatric nonalcoholic fatty liver disease : impact of inborn errors of metabolism : reply

Ilya QuerterRuth De BruyneAnja GeertsSander Lefere

A1 Journal Article in CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

Pretransplant changes in serum protein glycosylation relate to risk of HCC recurrence after liver transplantation and provide a potential prognostic biomarker : a proof-of-concept study

Xavier VerhelstHeleen EngelsAnja GeertsAude VanlanderLuis Abreu De CarvalhoHelena DegrooteLeander MeurisFrederik BerrevoetNico CallewaertHans Van Vlierberghe

Rare case of ascites several years after liver transplantation

Liesbeth DerooAnne HoorensXavier VerhelstHelena DegrooteHans Van VlierbergheAnja Geerts

Editorial material

Validation of a glycomics-based test associated with risk of HCC development in cirrhosis

Xavier VerhelstLeander MeurisRoos ColmanAnnelies Van HeckeAnja GeertsNico CallewaertHans Van Vlierberghe

Y-90 radioembolization versus drug-eluting bead chemoembolization for unresectable hepatocellular carcinoma : results from the TRACE phase II randomized controlled trial

Elisabeth DhondtBieke LambertLaurens HermieLynn HuyckPeter VanlangenhoveAnja GeertsXavier VerhelstMaridi AertsAude VanlanderFrederik Berrevoet et al.

A1 Journal Article in RADIOLOGY

Yttrium-90 radioembolization versus drug-eluting beads chemoembolization for unresectable hepatocellular carcinoma : results from the TRACE phase 2 randomized controlled trial

Elisabeth DhondtBieke LambertLaurens HermieLynn HuyckPeter VanlangenhoveAnja GeertsXavier VerhelstMaridi AertsAude VanlanderFrederik Berrevoet et al.

2021

A placebo-controlled trial of subcutaneous semaglutide in nonalcoholic steatohepatitis

Philip NewsomeKristine BuchholtzKenneth CusiMartin LinderTakeshi OkanoueVlad RatziuArun SanyalAnne-Sophie SejlingStephen HarrisonAnja Geerts et al.

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE

A randomized, controlled trial of the pan-PPAR agonist lanifibranor in NASH

Sven M. FrancquePierre BedossaVlad RatziuQuentin M. AnsteeElisabetta BugianesiArun J. SanyalRohit LoombaStephen A. HarrisonRozalina BalabanskaLyudmila Mateva et al.

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE

Bariatric surgery and the liver : mechanisms, benefits, and risks

Sander LefereLouis OnghenaAude VanlanderYves Van NieuwenhoveLindsey DevisscherAnja Geerts

A1 Journal Article in OBESITY REVIEWS

Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models

Helena DegrooteSander LefereAstrid VandierendonckBart VanderborghtTim MeeseFilip Van NieuwerburghXavier VerhelstAnja GeertsHans Van VlierbergheLindsey Devisscher

A2 Journal Article in ONCOTARGET

Focal eosinophilic infiltration of the liver, benign or malignant?

Wouter ClaeysAnke DeliePeter SmeetsMarie-Angélique De ScheerderHelena DegrooteXavier VerhelstHans Van VlierbergheAnja Geerts

A2 Journal Article in CLINICAL CASE REPORTS

Health status of patients with autoimmune hepatitis is not affected by the SARS-CoV-2 outbreak in Flanders, Belgium

Xavier VerhelstNicky SomersAnja GeertsHelena DegrooteHans Van Vlierberghe

A1 Journal Article in JOURNAL OF HEPATOLOGY

Intensive lifestyle management improves steatosis and fibrosis in pediatric metabolic-associated fatty liver disease

Sander LefereEllen DupontAnn De GuchtenaereStephanie Van BiervlietSaskia Vande VeldeXavier VerhelstLindsey DevisscherHans Van VlierbergheAnja GeertsRuth De Bruyne

NOX1 inhibition attenuates the development of a pro‐tumorigenic environment in experimental hepatocellular carcinoma

Aster VandierendonckHelena DegrooteBart VanderborghtXavier VerhelstAnja GeertsLindsey DevisscherHans Van Vlierberghe

A1 Journal Article in JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Serum glycomics 7 days after liver transplantation relate to graft loss 3 months after liver transplantation independently of early allograft dysfunction

Xavier VerhelstAnja GeertsRachel ColmanAude VanlanderLuis Filipe Abreu de CarvalhoRoberto TroisiFrederik BerrevoetXavier RogiersNadine CallewaertHans Van Vlierberghe et al.

Serum glycomics on postoperative day 7 are associated with graft loss within 3 months after liver transplantation regardless of early allograft dysfunction

Xavier VerhelstAnja GeertsRoos ColmanAude VanlanderHelena DegrooteLuis Abreu De CarvalhoLeander MeurisFrederik BerrevoetXavier RogiersNico Callewaert et al.

A1 Journal Article in TRANSPLANTATION

The neurogliovascular unit in hepatic encephalopathy

Wouter ClaeysLien Van HoeckeSander LefereAnja GeertsXavier VerhelstHans Van VlierbergheHelena DegrooteLindsey DevisscherRoosmarijn VandenbrouckeChristophe Van Steenkiste

A1 Journal Article in JHEP REPORTS

The utility of biomarkers in prognosis assessment of patients with acute liver failure

Pauline De ClercqAnja GeertsHans Van VlierbergheXavier Verhelst

A1 Journal Article in HEPATOLOGY RESEARCH

2020

A murine model of hepatic encephalopathy : validation and neurobehavioral testing

Wouter ClaeysAnja GeertsSander LefereHans Van VlierbergheGriet Van ImschootElien Van WonterghemRoosmarijn VandenbrouckeChristophe Van Steenkiste

Angiogenesis in the progression of non-alcoholic fatty liver disease

Sander LefereLindsey DevisscherAnja Geerts

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Bariatric surgery patients are at risk for alcoholic liver disease with need for liver transplantation

Sander LefereLenka StroobantXavier VerhelstAude VanlanderFrederik BerrevoetRoberto TroisiYves Van NieuwenhoveXavier RogiersHans Van VlierbergheAnja Geerts

A1 Journal Article in OBESITY SURGERY

Charting extracellular transcriptomes in the human biofluid RNA atlas

Eva HulstaertAnnelien MorlionFrancisco Avila CobosKimberly VerniersJustine NuytensEveline Vanden EyndeNurten YigitJasper AnckaertAnja GeertsPieter Hindryckx et al.

A1 Journal Article in CELL REPORTS

Combination of sivelestat and N-acetylcysteine alleviates the inflammatory response and exceeds standard treatment for acetaminophen-induced liver injury

Sarah RaevensSanne Van CampenhoutPieter-Jan DebackerSander LefereXavier VerhelstAnja GeertsHans Van VlierbergheIsabelle ColleLindsey Devisscher

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

Combination therapy with a dual CCR2/CCR5 antagonist and a FGF21 analogue synergizes in ameliorating steatohepatitis and fibrosis

Tobias PuengelSander LefereJana HundertmarkChristian PennersFrederique Van de VeldeBruno LapauwLindsey DevisscherAnja GeertsStephanie BoehmZhao Qihong Zhao Qihong et al.

Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages

Sander LefereTobias PuengelJana HundertmarkChristian PennersAnna Katharina FrankAdrien GuillotKevin De MuynckFelix HeymannVanessa AdarbesEvelyne Defrene et al.

A1 Journal Article in JOURNAL OF HEPATOLOGY

Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model

Bart VanderborghtKevin De MuynckSander LefereAnja GeertsHelena DegrooteXavier VerhelstHans Van VlierbergheLindsey Devisscher

A2 Journal Article in ONCOTARGET

Histologically proven hepatic steatosis associates with lower testosterone levels in men with obesity

Frederique Van de VeldeMarlies BekaertAnne HoorensAnja GeertsGuy T'SjoenTom FiersJean KaufmanYves Van NieuwenhoveBruno Lapauw

A1 Journal Article in ASIAN JOURNAL OF ANDROLOGY

Myeloid IRE1a deletion alters hepatic macrophage phenotype and attenuates experimental non-alcoholic steatohepatitis-related hepatocellular carcinoma

Sanne Van CampenhoutLaurentijn TillemanSander LefereAstrid VandierendonckAnja GeertsXavier VerhelstFilip Van NieuwerburghHans Van VlierbergheLindsey Devisscher

Myeloid-specific IRE1alpha deletion reduces tumour development in a diabetic, non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model

Sanne Van CampenhoutLaurentijn TillemanSander LefereAster VandierendonckSarah RaevensXavier VerhelstAnja GeertsFilip Van NieuwerburghHans Van VlierbergheLindsey Devisscher

A1 Journal Article in METABOLISM-CLINICAL AND EXPERIMENTAL

Patients with chronic hepatitis C virus infection are at high risk of being lost to follow-up : focused interventions can increase linkage to care

Hannah KeymeulenHannah Van de VeldeHelena DegrooteAnja GeertsHans Van VlierbergheXavier Verhelst

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Up to 50% of portal vein thrombosis remains undiagnosed until liver transplantation

Josephine BertAnja GeertsAude VanlanderLUIS ABREU DE CARVALHOHelena DegrooteFrederik BerrevoetXavier RogiersHans Van VlierbergheXavier Verhelst

A1 Journal Article in CLINICAL TRANSPLANTATION

Vasomodulators and liver transplantation for portopulmonary hypertension : evidence from a systematic review and meta-analysis

Rebecca DerooEric TrepoTom HolvoetMichel De PauwAnja GeertsXavier VerhelstIsabelle ColleHans Van VlierbergheMichael B. FallonSarah Raevens

A1 Journal Article in HEPATOLOGY

2019

Angiogenesis and macrophages as diagnostic and therapeutic targets in non-alcoholic fatty liver disease

Sander LefereAnja GeertsLindsey DevisscherChristophe Van Steenkiste

Angiopoietin-2 promotes pathological angiogenesis and is a therapeutic target in murine nonalcoholic fatty liver disease

Sander LefereFrederique Van de VeldeAnne HoorensSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytBert VandeghinsteChristian VanhoveCharlotte Debbaut et al.

A1 Journal Article in HEPATOLOGY

Insulin resistance associates with hepatic lobular inflammation in subjects with obesity

Frederique Van de VeldeMarlies BekaertAnja GeertsAnne HoorensArsène-Hélène BatensSamiah ShadidMargriet OuwensYves Van NieuwenhoveBruno Lapauw

A1 Journal Article in ENDOCRINE CONNECTIONS

Myeloid-specific IRE1 alpha deletion reduces tumour development in a non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model

Sanne Van CampenhoutSander LefereAster VandierendonckXavier VerhelstAnja GeertsHans Van VlierbergheLindsey Devisscher

Obeticholic acid for the treatment of non-alcoholic steatohepatitis : interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial

Zobair M YounossiVlad RatziuRohit LoombaMary RinellaQuentin M AnsteeZachary GoodmanPierre BedossaAndreas GeierSusanne BeckebaumPhilip N Newsome et al.

A1 Journal Article in LANCET

Oral vasodilator treatment and liver transplantation for portopulmonary hypertension : systematic review and meta-analysis of hemodynamic response and prognosis

Rebecca DerooMichel De PauwEric TrepoTom HolvoetAnja GeertsXavier VerhelstIsabelle ColleHans Van VlierbergheSarah Raevens

Outcome of liver transplantation for hepatopulmonary syndrome : a Eurotransplant experience

Sarah RaevensXavier RogiersAnja GeertsXavier VerhelstUndine SamuelMarieke van RosmalenGabriela BerlakovichJean DelwaideOlivier DetryFrank Lehner et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Portal vein thrombosis in patients on the waiting list for liver transplantation : a single center cohort study

Josephine BertAnja GeertsAude VanlanderLUIS ABREU DE CARVALHOFrederik BerrevoetRoberto TroisiXavier RogiersHans Van VlierbergheXavier Verhelst

Portal vein thrombosis on the waiting list for liver transplantation : a single center cohort study

Josephine BertAnja GeertsAude VanlanderLUIS ABREU DE CARVALHOFrederik BerrevoetRoberto TroisiXavier RogiersHans Van VlierbergheXavier Verhelst

Screening for hepatitis C viral infection in a non-urban primary care facility in Flanders

Xavier VerhelstG. DevolderM. De WildeL. GoderisA. De BelEmiel SpillebeenAnja GeertsAnselme DereseHans Van Vlierberghe

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Serum glycomics on postoperative day 7 are associated with graft loss 3 months after liver transplantation

Xavier VerhelstAnja GeertsRoos ColmanAude VanlanderLUIS ABREU DE CARVALHOFrederik BerrevoetRoberto TroisiXavier RogiersNico CallewaertHans Van Vlierberghe

The human biofluid RNA atlas : expanding the liquid biopsy field beyond the blood stream

Eva HulstaertKimberly VerniersJustine NuytensEveline Vanden EyndeNurten YigitJasper AnckaertAnja GeertsPeggy JacquesGuy BrusselleTHIERRY DERVEAUX et al.

The potential of glycomics as prognostic biomarkers in liver disease and liver transplantation

Xavier VerhelstAnja GeertsNico CallewaertHans Van Vlierberghe

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Update on liver transplantation for cholangiocarcinoma : a review of the recent literature

Stéphanie LaurentXavier VerhelstAnja GeertsKaren GeboesMarc De ManRoberto TroisiAude VanlanderXavier RogiersFrederik BerrevoetHans Van Vlierberghe

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Why pulse oximetry is inaccurate in liver cirrhosis : ancient knowledge

Sarah RaevensIsabelle ColleAnja GeertsHans Van Vlierberghe

A1 Journal Article in HEPATOLOGY

2018

A new 'treatment-response score' for AUTO immune hepatitis is predictive of LONG-TERM event-free survival and overall survival : a multicenter Belgian cohort study

Cedric SimoenJeoffrey SchoutenIsabelle ColleChristophe van SteenkisteFilip SermonAnne HoorensAnja GeertsHans Van VlierbergheXavier Verhelst

Advances in the approach to pulmonary vascular complications of liver disease

Sarah RaevensIsabelle ColleAnja Geerts

Angiopoietin-2 as therapeutic target for pathological angiogenesis and inflammation in non-alcoholic steatohepatitis

Sander LefereF Van de VeldeSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytChristian VanhoveAnne HoorensCHRISTINE CASTELEYNXavier Verhelst et al.

Angiopoietin-2 as therapeutic target for pathological angiogenesis and inflammation in non-alcoholic steatohepatitis

Sander LefereFrederique Van de VeldeSarah RaevensSanne Van CampenhoutAster VandierendonckS NeytChristian VanhoveAnne HoorensChristophe CasteleynXavier Verhelst et al.

Angiopoietin-2 promotes pathological angiogenesis and is a novel therapeutic target in non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeAnne HoorensSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytBert VandeghinsteChristian VanhoveCharlotte Debbaut et al.

Clinical burden of hepatitis E virus infection in a tertiary care center in Flanders, Belgium

Lien CattoirFREDERIK VAN HOECKETom Van MaerkenEline NysINGE RYCKAERTMatthias De BoulleAnja GeertsXavier VerhelstIsabelle ColleVeronik Hutse et al.

A1 Journal Article in JOURNAL OF CLINICAL VIROLOGY

Cu isotope ratio shifts in common bile duct ligated mice and correlates with the degree of cholestatic-induced liver disease

Sanne Van CampenhoutMarta Costas RodriguezAgustina Ari Murti Budi HastutiSarah RaevensAnja GeertsXavier VerhelstFrank VanhaeckeHans Van VlierbergheLindsey Devisscher

Evaluation of compliance in young transplant patients

Anja GeertsRuth De BruyneXavier RogiersArnaud VanlanderProf dr Carine Poppe

Glycome patterns of perfusate in livers before transplantation associate with primary non-function

Xavier VerhelstAnja GeertsIna JochmansDieter VanderschaegheAgnes ParadissisAude VanlanderFrederik BerrevoetGéraldine DahlqvuistFrederik NevensJacques Pirenne et al.

A1 Journal Article in GASTROENTEROLOGY

Hepatic changes in the fontan circulation : identification of liver dysfunction and an attempt to streamline follow-up screening

Thomas AckermanAnja GeertsHans Van VlierbergheJulie De BackerKatrien Francois

A1 Journal Article in PEDIATRIC CARDIOLOGY

Model for end-stage liver disease score and hemodynamic instability as a predictor of poor outcome in early transjugular intrahepatic portosystemic shunt treatment for acute variceal hemorrhage

Laurens HermieElisabeth DhondtPeter VanlangenhoveEric HosteAnja GeertsLuc Defreyne

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Placental growth factor inhibition targets pulmonary angiogenesis and represents a therapy for hepatopulmonary syndrome in mice

Sarah RaevensAnja GeertsAnnelies ParidaensSander LefereXavier VerhelstAnne HoorensJo Van DorpeTania MaesKen BrackeChristophe Casteleyn et al.

A1 Journal Article in HEPATOLOGY

Preclinical and clinical therapeutic strategies affecting tumor-associated macrophages in hepatocellular carcinoma

Helena DegrooteAlex van DierendonckAnja GeertsHans Van VlierbergheLindsey Devisscher

A1 Journal Article in JOURNAL OF IMMUNOLOGY RESEARCH

Secondary adrenal insufficiency after treatment with budesonide for autoimmune hepatitis

Filip De MaeyerBruno LapauwAnne HoorensAnja GeertsHans Van VlierbergheXavier Verhelst

A2 Journal Article in CASE REPORTS IN GASTROENTEROLOGY

Severe hepatic and pulmonary involvement in Rendu-Osler-Weber syndrome

Xavier VerhelstAnja GeertsHans Van VlierberghePeter SmeetsCLARISSE LECLUYSE

A2 Journal Article in CASE REPORTS IN GASTROENTEROLOGY

The combination of N-acetylcysteine and anti-MT antibodies as novel therapy for acetaminophen-induced liver injury

Lindsey DevisscherDebby LaukensHannelore Van EeckhoutteSarah RaevensSander LefereAnne HoorensXavier VerhelstM LynesAnja GeertsHans Van Vlierberghe

2017

A glycomic based serum marker analysed on postoperative day 7 after liver transplantation is an independent predictor of graft and patient survival during the first year after liver transplantation

Xavier VerhelstAnja GeertsXavier RogiersAude VanlanderFrederik BerrevoetNico CallewaertRoberto TroisiHans Van Vlierberghe

A glycomic serum marker analysed at one week after liver transplantation is an independent predictor of graft loss during the first year after liver transplantation

Xavier VerhelstAnja GeertsXavier RogiersAude VanlanderFrederik BerrevoetNico CallewaertRoberto TroisiHans Van Vlierberghe

A glycomic serum marker analysed at one week after liver transplantation is an independent predictor of graft loss during the first year after liver transplantation

Xavier VerhelstAnja GeertsXavier RogiersAude VanlanderFrederik BerrevoetNico CallewaertHans Van Vlierberghe

A glycomics-based test predicts the development of hepatocellular carcinoma in cirrhosis

Xavier VerhelstDieter VanderschaegheLaurent CasteraTom RaesAnja GeertsClaire FrancozRoos ColmanFrançois DurandNico CallewaertHans Van Vlierberghe

A1 Journal Article in CLINICAL CANCER RESEARCH

A pretransplant glycomic signature in perfusate is predictive of primary non function after liver transplantation

Xavier VerhelstAnja GeertsXavier RogiersAude VanlanderFrederik BerrevoetNico CallewaertRoberto TroisiHans Van Vlierberghe

Anti-placental growth factor therapy attenuates experimental hepatopulmonary syndrome

Sarah RaevensAnnelies ParidaensSander LefereChristophe CasteleynB JonckxXavier VerhelstHans Van VlierbergheChristophe Van SteenkisteAnja GeertsLindsey Devisscher et al.

Combination of tauroursodeoxycholic acid and N-acetylcysteine exceeds standard treatment for acetaminophen intoxication

Annelies ParidaensSarah RaevensIsabelle ColleEliene BogaertsYves-Paul VandewynckelXavier VerhelstAnne HoorensLeo A van GrunsvenHans Van VlierbergheAnja Geerts et al.

A1 Journal Article in LIVER INTERNATIONAL

Early TIPS placement as a feasible and safe strategy for variceal bleeding in high risk liver patients : a 5-year monocentre experience

Ewout VerlyXavier VerhelstHans Van VlierbergheAnja Geerts

Een jonge vrouw met necrotiserende granulomen in de lever

Joris RötgensHelena DegrooteAnne HoorensPeter SmeetsAnja Geerts

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Ernstige icterische hepatitis na eenmalig gebruik van 'ecstasy'

Ruth BottermanXavier VerhelstAnja GeertsHans Van Vlierberghe

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Hepatitis E virus serology and PCR : does the methodology matter?

Lien CattoirFREDERIK VAN HOECKETom Van MaerkenEVELINE NYSINGE RYCKAERTMatthias De BoulleAnja GeertsXavier VerhelstIsabelle ColleVeronik Hutse et al.

A1 Journal Article in ARCHIVES OF VIROLOGY

Koorts, keelpijn en leverfalen

Marie De GrooteJeroen GeldofAnne HoorensXavier VerhelstRoberto TroisiHarald PeetersHans Van VlierbergheAnja Geerts

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Kupffer cell pool is maintained by local proliferation and the differentiation of bone marrow monocytes into short-lived monocyte-derived Kupffer cells during non-alcoholic steatohepatitis and recovery

Lindsey DevisscherCharlotte ScottSander LefereSarah RaevensEliene BogaertsAnnelies ParidaensXavier VerhelstAnja GeertsMartin GuilliamsHans Van Vlierberghe

Modulation of endoplasmic reticulum stress induced tissue damage in acute and chronic liver failure

Annelies ParidaensIsabelle ColleAnja Geerts

Modulation of the unfolded protein response by tauroursodeoxycholic acid counteracts apoptotic cell death and fibrosis in a mouse model for secondary biliary liver fibrosis

Annelies ParidaensSarah RaevensLindsey DevisscherEliene BogaertsXavier VerhelstAnne HoorensHans Van VlierbergheLeo van GrunsvenAnja GeertsIsabelle Colle

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Non-alcoholic steatohepatitis induces transient changes within the liver macrophage pool

Lindsey DevisscherCharlotte ScottSander LefereSarah RaevensEliene BogaertsAnnelies ParidaensXavier VerhelstAnja GeertsMartin GuilliamsHans Van Vlierberghe

A1 Journal Article in CELLULAR IMMUNOLOGY

Pretransplant glycomic analysis of perfusate is predictive of primary non function after liver transplantation

Xavier VerhelstAnja GeertsDieter VanderschaegheXavier RogiersAude VanlanderFrederik BerrevoetNico CallewaertRoberto TroisiHans Van Vlierberghe

Pretransplant glycomic analysis of perfusate is predictive of primary non function after liver transplantation : a proof of concept

Xavier VerhelstAnja GeertsXavier RogiersAude VanlanderFrederik BerrevoetNico CallewaertRoberto TroisiHans Van Vlierberghe

Refractory subacute steatohepatitis after biliopancreatic diversion

Sander LefereAnne HoorensSarah RaevensRoberto TroisiXavier VerhelstHans Van VlierbergheAnja Geerts

Editorial material

Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeLindsey DevisscherMarlies BekaertSarah RaevensXavier VerhelstYves Van NieuwenhoveMarleen PraetAnne HoorensChristophe Van Steenkiste et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF OBESITY

Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in obese patients with non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeLindsey DevisscherMarlies BekaertSarah RaevensXavier VerhelstYves Van NieuwenhoveMarleen PraetAnne HoorensChristophe Van Steenkiste et al.

Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in obese patients with non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeLindsey DevisscherMarlies BekaertSarah RaevensXavier VerhelstYves Van NieuwenhoveMarleen PraetAnne HoorensChristophe Van Steenkiste et al.

2016

Association of recently described adipokines with liver histology in biopsy-proven non-alcoholic fatty liver disease: a systematic review

Marlies BekaertXavier VerhelstAnja GeertsBruno LapauwPatrick Calders

A1 Journal Article in OBESITY REVIEWS

Cirrhosis : reviewing the literature and future perspectives

Xavier VerhelstAnja GeertsHans Van Vlierberghe

A2 Journal Article in EUROPEAN MEDICAL JOURNAL. HEPATOLOGY

Comments on the impact of genotyping method on the subtype distribution of HCV genotype 1

Celien Van den BorreWIM SCHUERMANSHans Van VlierbergheAnja GeertsXavier VerhelstElizaveta Padalko

A1 Journal Article in JOURNAL OF CLINICAL VIROLOGY

Effect of prolyl hydroxylase domain 2 haplodeficiency on liver progenitor cell characteristics in early mouse hepatocarcinogenesis

Eliene BogaertsAnnelies ParidaensXavier VerhelstPeter CarmelietAnja GeertsHans Van VlierbergheLindsey Devisscher

A1 Journal Article in EXCLI JOURNAL

Elafibranor, an agonist of the peroxisome proliferator−activated receptor−α and −δ, induces resolution of nonalcoholic steatohepatitis without fibrosis worsening

Vlad RatziuStephen A. HarrisonSven FrancquePierre BedossaPhilippe LehertLawrence SerfatyManuel Romero-GomezJérôme BoursierManal AbdelmalekSteve Caldwell et al.

A1 Journal Article in GASTROENTEROLOGY

Enuresis nocturna : a malignant symptom?

K VlaemynckBram De WildeRoberto TroisiXavier RogiersAnja GeertsXavier VerhelstHans Van VlierbergheRuth De Bruyne

Fototoxiciteit na de inname van simeprevir voor de behandeling van hepatitis C

Hendrik ThoenFlorence DesmidtAnja GeertsIsabelle HoorensHans Van VlierbergheXavier Verhelst

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Heads or tails : genotyping of hepatitis C virus concerning the 2k/1b circulating recombinant form

WIM SCHUERMANSHans OrlentIsabelle DesomberePatrick DescheemaekerHans Van VlierbergheAnja GeertsXavier VerhelstMarijke ReyndersElizaveta Padalko

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Health-related quality of life improves further after liver transplantation and is influenced by length of stay

Louis OnghenaWouter DeveltereXavier RogiersRoberto TroisiFrederik BerrevoetAude VanlanderAnja GeertsHans Van VlierbergheXavier VerhelstProf dr Carine Poppe

Health-related quality of life is improved after liver transplantation and is related to disease acceptance, helplessness and perceived disease benefits

Louis OnghenaWouter DeveltereXavier RogiersRoberto TroisiFrederik BerrevoetAude VanlanderAnja GeertsHans Van VlierbergheProf dr Carine PoppeXavier Verhelst

Hepatitis E virus seroprevalence in East- and West Flanders, Belgium : comparison between 2011 and 2016

L CattoirE NysHans Van VlierbergheAnja GeertsXavier VerhelstElizaveta Padalko

Hypoxia-regulated mechanisms in the pathogenesis of obesity and non-alcoholic fatty liver disease

Sander LefereChristophe Van SteenkisteXavier VerhelstHans Van VlierbergheLindsey DevisscherAnja Geerts

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Impact of the genotyping method on the distribution of hepatitis C virus subtypes of genotype 1

C Van den BorreW SchuermansHans Van VlierbergheAnja GeertsXavier VerhelstE Padalko

Kinetics of pulmonary angiogenesis in mouse common bile duct ligation-induced liver fibrosis

Sarah RaevensLindsey DevisscherAnnelies ParidaensEliene BogaertsSander LefereYves-Paul VandewynckelCHRISTINE CASTELEYNKen BrackeTania MaesXavier Verhelst et al.

Longitudinal transient elastography measurements used in follow-up for patients with cystic fibrosis

Stephanie Van BiervlietHUGO VERDIEVELStefanie Vande VeldeRuth De BruyneDanny De LoozeXavier VerhelstAnja GeertsEddy RobberechtHans Van Vlierberghe

A1 Journal Article in ULTRASOUND IN MEDICINE AND BIOLOGY

Massief subcapsulair leverhematoom in een zwangerschap verwikkeld met het HELLP-syndroom

Hendrik ThoenSaartje ThijsHans Van VlierbergheXavier VerhelstAnja Geerts

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Next-generation proteasome inhibitor oprozomib synergizes with modulators of the unfolded protein response to suppress hepatocellular carcinoma

Yves-Paul VandewynckelCéline CouckeDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsAster VandierendonckSarah RaevensXavier VerhelstChristophe Van Steenkiste et al.

A1 Journal Article in ONCOTARGET

Next-generation proteasome inhibitor oprozomib synergizes with modulators of the unfolded protein response to suppress hepatocellular carcinoma

Yves-Paul VandewynckelCéline CouckeDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsAster VandierendonckSarah RaevensXavier VerhelstChristophe Van Steenkiste et al.

Placental growth factor inhibition alleviates hepatopulmonary syndrome in mice

Sarah RaevensAnnelies ParidaensSander LefereBart JonckxXavier VerhelstHans Van VlierbergheChristophe Van SteenkisteAnja GeertsLindsey DevisscherIsabelle Colle

Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherEliene BogaertsAnnelies ParidaensAnja Van den BusscheSarah RaevensXavier VerhelstChristophe Van SteenkisteBart Jonckx et al.

A1 Journal Article in BMC CANCER

Quality of life after liver transplantation : state of the art

Louis OnghenaWouter DeveltereProf dr Carine PoppeAnja GeertsRoberto TroisiAude VanlanderFrederik BerrevoetXavier RogiersHans Van VlierbergheXavier Verhelst

A2 Journal Article in WORLD JOURNAL OF HEPATOLOGY

Reduced expression of chemerin in visceral adipose tissue associates with hepatic steatosis in patients with obesity

Marlies BekaertMargriet OuwensTina HörbeltFrederique Van de VeldePia FahlbuschDaniella Herzfeld de WizaYves Van NieuwenhovePatrick CaldersMarleen PraetAnne Hoorens et al.

A1 Journal Article in OBESITY

Serum N-glycans show distinct alterations during acetaminophen-induced acute liver failure and are predictive of transplant free survival : a proof-of-concept

Xavier VerhelstAnja GeertsXavier RogiersAude VanlanderFrederik BerrevoetFrançois DurandRoberto TroisiHans Van Vlierberghe

Successful treatment of HCV-associated B-cell non-Hodgkin lymphomas with direct-acting antiviral agents

FREDERIK DE CLERCKAnja GeertsLieve BrochezReinhart SpeeckaertTom BoterbergHans Van VlierbergheXavier Verhelst

A1 Journal Article in JOURNAL OF CLINICAL GASTROENTEROLOGY

The bile acid tauroursodeoxycholic acid cooperates with N-acetylcysteine in the treatment of experimental acetaminophen-induced hepatotoxicity

Annelies ParidaensLindsey DevisscherSarah RaevensEliene BogaertsYves-Paul VandewynckelXavier VerhelstI MannaertsL Van GrunsvenHans Van VlierbergheIsabelle Colle et al.

The role of macrophages in obesity-driven chronic liver disease

Lindsey DevisscherXavier VerhelstIsabelle ColleHans Van VlierbergheAnja Geerts

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

The unfolded protein response underlies microenvironmental stress-induced phenotype switching leading to stemness and chemoresistance in human hepatocellular carcinoma

Yves-Paul VandewynckelO GovaereAster VandierendonckDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsSarah RaevensXavier VerhelstChristophe Van Steenkiste et al.

2015

Assesment of serum glycomics (GlycoCirrhoTest) for risk prediction of hepatocellular carcinoma development in patients with cirrhosis

Xavier VerhelstDieter VanderschaegheLaurent CasteraAnja GeertsNathalie GoutteClaire FrancozFrançois DurandNico CallewaertHans Van Vlierberghe

Assesment of serum glycomics (GlycoCirrhoTest) for risk prediction of hepatocellular carcinoma development in patients with cirrhosis

Xavier VerhelstDieter VanderschaegheLaurent CasteraAnja GeertsNathalie GoutteClaire FrancozFrançois DurandNico CallewaertHans Van Vlierberghe

Evaluation of the value of serum glycomics (GlycoCirrhoTest) for risk prediction of hepatocellular carcinoma in compensated cirrhosis

Xavier VerhelstDieter VanderschaegheLaurent CasteraAnja GeertsNathalie GoutteClaire FrancozFrançois DurandNico CallewaertHans Van Vlierberghe

Health-related quality of life is improved after liver transplantation and is related to disease acceptance, helplessness and perceived disease benefits

Wouter DeveltereLouis OnghenaXavier RogiersRoberto TroisiFrederik BerrevoetAude VanlanderAnja GeertsHans Van VlierbergheXavier VerhelstProf dr Carine Poppe

Health-related quality of life is improved after liver transplantation and is related to disease acceptance, helplessness and perceived disease benefits

Louis OnghenaWouter DeveltereXavier RogiersRoberto TroisiFrederik BerrevoetAude VanlanderAnja GeertsHans Van VlierbergheXavier VerhelstProf dr Carine Poppe

Hepatitis E virus serology and PCR : does the methodology matter?

Lien CattoirFREDERIK VAN HOECKETom Van MaerkenEVELINE NYSINGE RYCKAERTMatthias De BoulleAnja GeertsXavier VerhelstHans Van VlierbergheElizaveta Padalko

Hepatopulmonary syndrome and portopulmonary hypertension : recent knowledge in pathogenesis and overview of clinical assessment

Sarah RaevensAnja GeertsChristophe Van SteenkisteXavier VerhelstHans Van VlierbergheIsabelle Colle

A1 Journal Article in LIVER INTERNATIONAL

IgG4-related cholangitis : case report and literature review

ANNELEEN DE BOTHHans Van VlierbergheAnja GeertsLouis LibbrechtXavier Verhelst

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Impact on angiogenesis and ER stress and its effect on chemoresistance through PlGF inhibition in a mouse model of hepatocellular carcinoma

Yves-Paul VandewynckelHans Van VlierbergheAnja Geerts

Intramuscular hepatitis B immunoglobulins for reinfection control after liver transplantation: a cost-saving alternative

Eva HulstaertXavier VerhelstAnja GeertsHans Van Vlierberghe

A1 Journal Article in JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH

Liver transplantation for hepatocellular carcinoma comparing the Milan, UCSF, and Asan criteria: long-term follow-up of a Western single institutional experience

Italo BonadioIsabelle ColleAnja GeertsPeter SmeetsGiammauro BerardiMarleen PraetXavier RogiersBernard de HemptinneHans Van VlierbergheRoberto Troisi

A1 Journal Article in CLINICAL TRANSPLANTATION

Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy

Yves-Paul VandewynckelDebby LaukensEliene BogaertsAnnelies ParidaensAnja Van den BusscheXavier VerhelstChristophe Van SteenkisteBenedicte DescampsChristian VanhoveLouis Libbrecht et al.

A1 Journal Article in HEPATOLOGY INTERNATIONAL

Phase I dose-escalation study evaluating the safety and pharmacokinetics of oral artesunate in patients with advanced hepatocullular carcinoma (DESPARTH trial)

Yves-Paul VandewynckelK RombautsXavier VerhelstLucas Van BortelBart De SpiegeleerAnja GeertsHans Van Vlierberghe

Placental growth factor inhibition modulates the interplay between hypoxia and the unfolded protein response in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsXavier VerhelstAnja Van den BusscheSarah RaevensChristophe Van SteenkisteB Jonckx et al.

Role of angiogenic factors/cell adhesion markers in serum of cirrhotic patients with hepatopulmonary syndrome

Sarah RaevensStephanie CoulonChristophe Van SteenkisteRoos ColmanXavier VerhelstHans Van VlierbergheAnja GeertsThomas PerkmannThomas HorvatitsValentin Fuhrmann et al.

A1 Journal Article in LIVER INTERNATIONAL

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsXavier VerhelstAnja Van den BusscheSarah RaevensChristophe Van SteenkisteMarleen Van Troys et al.

A1 Journal Article in ONCOTARGET

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsXavier VerhelstA Van den BusscheSarah RaevensChristophe Van SteenkisteMarleen Van Troys et al.

Time-dependent effect of hypoxia on tumor progression and liver progenitor cell markers in primary liver tumors

Eliene BogaertsFemke HeindryckxLindsey DevisscherAnnelies ParidaensYves-Paul VandewynckelAnja Van den BusscheXavier VerhelstLouis LibbrechtLeo A van GrunsvenAnja Geerts et al.

A1 Journal Article in PLOS ONE

Varices, portal hypertensive gastropathy and GAVE

Isabelle ColleXavier VerhelstAnja GeertsHans Van Vlierberghe

Bookchapter in Cirrhosis : a practical guide to management

2014

Clinical burden of hepatitis E infections in Belgium

Elizaveta PadalkoFREDERIK VAN HOECKETom Van MaerkenLien CattoirEVELINE NYSINGE RYCKAERTMatthias De BoulleAnja GeertsXavier VerhelstIsabelle Colle et al.

Cutaneous infection by Alternaria infectoria in a liver transplant recipient: a case report

E CoussensS RoggeMarc HaspeslaghAnja GeertsXavier VerhelstHans Van VlierbergheRoberto TroisiIsabelle Colle

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Endoplasmic reticulum stress and angiogenesis: is there an interaction between them?

Annelies ParidaensDebby LaukensYves-Paul VandewynckelStephanie CoulonHans Van VlierbergheAnja GeertsIsabelle Colle

A1 Journal Article in LIVER INTERNATIONAL

Hepatitis mouse models : from acute-to-chronic autoimmune hepatitis

Muhammed YükselDebby LaukensFemke HeindrickxHans Van VlierbergheAnja GeertsF Susan WongLi WenIsabelle Colle

A1 Journal Article in INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Intramuscular hepatitis B immunoglobulines for reinfection control, a single centre experience

Eva HulstaertAnja GeertsXavier VerhelstAude VanlanderVINCENZO SCUDERIDavid LamFrederik BerrevoetXavier RogiersRoberto TroisiHans Van Vlierberghe

Living donor versus deceased donor liver transplantation for hepatocellular carcinoma comparing the Milan, UCSF and Asan criteria: long-term follow-up

Italo BonadioIsabelle ColleAnja GeertsPeter SmeetsMarleen PraetGiammauro BerardiBernard de HemptinneHans Van VlierbergheRoberto Troisi

Prevalence and outcome of diastolic dysfunction in liver transplantation recipients

Sarah RaevensMichel De PauwAnja GeertsFrederik BerrevoetXavier RogiersRoberto TroisiHans Van VlierbergheIsabelle Colle

A1 Journal Article in ACTA CARDIOLOGICA

Temporal dynamics and therapeutic potential of the unfolded protein espouse in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensAnja GeertsEliene BogaertsAnnelies ParidaensXavier VerhelstChristophe Van SteenkisteBenedicte DescampsChristian VanhoveLouis Libbrecht et al.

Temporal dynamics and therapeutic potential of the unfolded protein response in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensAnja GeertsEliene BogaertsAnnelies ParidaensXavier VerhelstChristophe Van SteenkisteBenedicte DescampsChristian VanhoveLouis Libbrecht et al.

Therapeutic effects of artesunate in hepatocellular carcinoma : repurposing an ancient antimalarial agent

Yves-Paul VandewynckelDebby LaukensAnja GeertsChristian VanhoveBenedicte DescampsLindsey DevisscherEliene BogaertsAnnelies ParidaensXavier VerhelstChristophe Van Steenkiste et al.

Therapeutic effects of artesunate in hepatocellular carcinoma: repurposing an ancient antimalarial agent

Yves-Paul VandewynckelDebby LaukensAnja GeertsChristian VanhoveBenedicte DescampsIsabelle ColleLindsey DevisscherEliene BogaertsAnnelies ParidaensXavier Verhelst et al.

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Treatment of HCC with intra-arterial yttrium-90 microspheres for downstaging patients to transplantation

Kathia De ManLuc DefreyneElisabeth DhondtELLEN DELANGHEXavier VerhelstPeter SmeetsHans Van VlierbergheAnja GeertsRoberto TroisiXavier Rogiers et al.

2013

Biomarkers for the diagnosis of acute cellular rejection in liver transplant recipients: a review

Xavier VerhelstRoberto TroisiIsabelle ColleAnja GeertsHans Van Vlierberghe

A1 Journal Article in HEPATOLOGY RESEARCH

Echocardiography for the detection of portopulmonary hypertension in liver transplant candidates: an analysis of cutoff values

Sarah RaevensIsabelle ColleKOEN REYNTJENSAnja GeertsFrederik BerrevoetXavier RogiersRoberto TroisiHans Van VlierbergheMichel De Pauw

A1 Journal Article in LIVER TRANSPLANTATION

Hepatocellular carcinoma (HCC) treatment with intra-arterial radiolabelled lipiodol versus Yttrium-90-microspheres: a retrospective survival analysis.

Kathia De ManLuc DefreyneELLEN DELANGHEElisabeth DhondtHans Van VlierbergheAnja GeertsXavier VerhelstRoberto TroisiBieke Lambert

Invasive aspergillosis in patients with cirrhosis, a case report and review of the last 10 years

Sarah JeurissenDirk VogelaersERICA SERMIJNK Van DyckeAnja GeertsHans Van VlierbergheIsabelle Colle

A1 Journal Article in ACTA CLINICA BELGICA

Liver transplantation for alcoholic liver disease: a retrospective analysis of recidivism, survival and risk factors predisposing to alcohol relapse

Elise DeruytterChristophe Van SteenkisteEric TrepoAnja GeertsHans Van VlierbergheFrederik BerrevoetBernard de HemptinneXavier RogiersRoberto TroisiIsabelle Colle

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Living related liver transplantation in an adult patient with hepatocellular adenoma and carcinoma 13 years after bone marrow transplantation for Fanconi anemia: a case report

Isabelle ColleGenevieve LaureysSarah RaevensLouis LibbrechtJuliaan LeroyKOEN REYNTJENSAnja GeertsXavier RogiersRoberto TroisiHolger Hoehn et al.

A1 Journal Article in HEPATOLOGY RESEARCH

Oral vasodilator therapy in patients with moderate to severe portopulmonary hypertension as a bridge to liver transplantation

Sarah RaevensMichel De PauwKOEN REYNTJENSAnja GeertsXavier VerhelstFrederik BerrevoetXavier RogiersRoberto TroisiHans Van VlierbergheIsabelle Colle

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Pathophysiology and management of post resection liver failure

Isabelle ColleXavier VerhelstAude VanlanderAnja GeertsHans Van VlierbergheFrederik BerrevoetXavier RogiersRoberto Troisi

A1 Journal Article in ACTA CHIRURGICA BELGICA

Role of vascular endothelial growth factor in the pathophysiology of nonalcoholic steatohepatitis in two rodent models

Stephanie CoulonVanessa LegryFemke HeindryckxChristophe Van SteenkisteChristophe CasteleynKim OlievierLouis LibbrechtPeter CarmelietBart JonckxJean-Marie Stassen et al.

A1 Journal Article in HEPATOLOGY

Serum protein N-glycan alterations of diethylnitrosamine-induced hepatocellular carcinoma mice and their evolution after inhibition of the placental growth factor

BRAM BLOMMEFemke HeindryckxJean Marie StassenAnja GeertsIsabelle ColleHans Van Vlierberghe

A1 Journal Article in MOLECULAR AND CELLULAR BIOCHEMISTRY

The paradox of the unfolded protein response in cancer

Yves-Paul VandewynckelDebby LaukensAnja GeertsEliene BogaertsAnnelies ParidaensXavier VerhelstSophie JanssensFemke HeindryckxHans Van Vlierberghe

A1 Journal Article in ANTICANCER RESEARCH

The placental growth factor as a target against hepatocellular carcinoma in a diethylnitrosamine induced mouse model

Femke HeindryckxStephanie CoulonEllen TerrieChristophe CasteleynJean-Marie StassenAnja GeertsLouis LibbrechtJoke AllemeerschPeter CarmelietIsabelle Colle et al.

A1 Journal Article in JOURNAL OF HEPATOLOGY

The role of vascular endothelial growth factor in non-alcoholic steatohepatitis

Stephanie CoulonAnja GeertsIsabelle Colle

The therapeutic potential of artesunate in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensAnja GeertsIsabelle ColleLouis LibbrechtEliene BogaertsLindsey DevisscherAnnelies ParidaensXavier VerhelstChristian Vanhove et al.

Treatment of hepatocellular carcinoma (HCC) with intraarterial yttrium-90 microspheres for downstaging patients to transplantation

Kathia De ManLuc DefreyneELLEN DELANGHEPeter SmeetsXavier VerhelstAnja GeertsHans Van VlierbergheXavier RogiersRoberto TroisiBieke Lambert

2012

Ascites: not always the usual suspects

CHRISTOPHE SNAUWAERTAnja GeertsIsabelle ColleHans Van Vlierberghe

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Effect of prolyl hydroxylase domain-2 haplodeficiency on the hepatocarcinogenesis in mice

Femke HeindryckxAnna KuchnioChristophe CasteleynStephanie CoulonKim OlievierIsabelle ColleAnja GeertsLouis LibbrechtPeter CarmelietHans Van Vlierberghe

A1 Journal Article in JOURNAL OF HEPATOLOGY

Evaluation of inflammatory and angiogenic factors in patients with non-alcoholic fatty liver disease

Stephanie CoulonSven FrancqueIsabelle ColleAn VerrijkenBRAM BLOMMEFemke HeindryckxSteffi De MunterJanne PrawittSandrine CaronBart Staels et al.

A1 Journal Article in CYTOKINE

Hepatitis E seroprevalence in Belgium

FREDERIK VAN HOECKETom Van MaerkenMatthias De BoulleAnja GeertsHans Van VlierbergheIsabelle ColleElizaveta Padalko

Hepatitis E seroprevalence in East and West Flanders, Belgium

FREDERIK VAN HOECKETom Van MaerkenMatthias De BoulleAnja GeertsHans Van VlierbergheIsabelle ColleElizaveta Padalko

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Inhibition of the placental growth factor decreases burden of cholangiocarcinoma and hepatocellular carcinoma in a transgenic mouse model

Femke HeindryckxEliene BogaertsStephanie CoulonHilde DevliesAnja GeertsLouis LibbrechtJean Marie StassenPeter CarmelietIsabelle ColleHans Van Vlierberghe

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

N-glycan based biomarker distinguishing non-alcoholic steatohepatitis from steatosis independently of fibrosis

BRAM BLOMMESven FrancqueEric TrépoLouis LibbrechtDieter VanderschaegheAn VerrijkenPiet PattynYves Van NieuwenhoveDirk Van de PutteAnja Geerts et al.

A1 Journal Article in DIGESTIVE AND LIVER DISEASE

Progressive familial intrahepatic cholestasis and benign recurrent intrahepatic cholestasis : a review

BEATRIJS STRUBBEAnja GeertsHans Van VlierbergheIsabelle Colle

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

2011

Angiogenesis in chronic liver disease and its complications

Stephanie CoulonFemke HeindryckxAnja GeertsChristophe Van SteenkisteIsabelle ColleHans Van Vlierberghe

A1 Journal Article in LIVER INTERNATIONAL

Inhibition of placental growth factor activity reduces the severity of fibrosis, inflammation, and portal hypertension in cirrhotic mice

Christophe Van SteenkisteJordi RiberaAnja GeertsMontse PautaSonia TuguesChristophe CasteleynLouis LibbrechtKim OlievierBen SchroyenHendrik Reynaert et al.

A1 Journal Article in HEPATOLOGY

Moyamoya disease as a possible cause of neurological impairment following liver transplantation for Wilson's disease

Frederico DesideriMassimo MarignaniOlivier VanovermeireIsabelle ColleGianfranco Delle FaveDimitri HemelsoetAnja GeertsHans Van Vlierberghe

A1 Journal Article in HEPATOLOGY RESEARCH

2010

Angiogenic changes in a new mouse model for hepatocellular carcinoma

Femke HeindryckxBert VandeghinsteLouis LibbrechtChristophe CasteleynSteven StaelensAnja GeertsIsabelle ColleHans Van Vlierberghe

Angiogenic changes in a new mouse model for hepatocellular carcinoma

Femke HeindryckxBert VandeghinsteLouis LibbrechtChristophe CasteleynSteven StaelensIsabelle ColleHans Van VlierbergheAnja Geerts

Angiogenic changes in a new mouse model for hepatocellular carcinoma assessed with state-of-the-art imaging technology

Femke HeindryckxBert VandeghinsteDominique SlaetsKoen MertensLouis LibbrechtChristophe CasteleynSteven StaelensAnja GeertsIsabelle ColleHans Van Vlierberghe

Angiogenic changes in a new mouse model for hepatocellular carcinoma assessed with state-of-the-art imaging technology

Femke HeindryckxBert VandeghinsteN CharetteDominique SlaetsLouis LibbrechtChristophe CasteleynSteven StaelensP StarkelAnja GeertsIsabelle Colle et al.

Angiogenic changes in a new mouse model for hepatocellular carcinoma assessed with state-of-the-art imaging technology

Femke HeindryckxBert VandeghinsteChristophe CasteleynNicolas CharetteDominique SlaetsLouis LibbrechtSteven StaelensPeter StärkelAnja GeertsIsabelle Colle et al.

Blockage of PLGF improves inflammation, fibrosis, and portal pressure in cirrhotic mice

Christophe Van SteenkisteJordi RiberaAnja GeertsSonia TuguesPeter CarmelietEkhart VerdegemLouis LibbrechtMartine De VosHans Van VlierbergheManuel Morales-Ruiz et al.

Early arterial revascularization after hepatic artery thrombosis may avoid graft loss and improve outcomes in adult liver transplantation

Andrea ScarinciMAURICIO SAINZ-BARRIGAFrederik BerrevoetB van den BosscheIsabelle ColleAnja GeertsXavier RogiersHans Van VlierbergheBernard de HemptinneRoberto Troisi

A1 Journal Article in TRANSPLANTATION PROCEEDINGS

Effect of PlGF-inhibition on survival in mice with hepatocellular carcinoma

Femke HeindryckxAnja GeertsPeter CarmelietIsabelle ColleHans Van Vlierberghe

Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease

Sara Van de VeireIngeborg StalmansFemke HeindryckxHajimu OuraAnnemilai Tijeras-RaballandThomas SchmidtSonja LogesImke AlbrechtBart JonckxStefan Vinckier et al.

A1 Journal Article in CELL

Graft loss is significantly decreased and long-term survival advantages are improved after urgent early (<= 15 days) arterial revascularization in adult liver transplantation

Andrea ScarinciMauricio Sainz-BarrigaIsabelle ColleAnja GeertsHans Van VlierbergheBERT VAN DEN BOSSCHEFrederik BerrevoetXavier RogiersRoberto TroisiBernard de Hemptinne

Hypomagnesemia and the risk of new onset diabetes after liver transplantation

Federico DesideriSTEVEN VAN LAECKEAnja GeertsHans Van VlierbergheFrederik BerrevoetXavier RogiersRoberto TroisiBernard de HemptinneRaymond VanholderIsabelle Colle

Hypomagnesemia and the risk of new-onset diabetes after liver transplantation

STEVEN VAN LAECKEFederico DesideriAnja GeertsHans Van VlierbergheFrederik BerrevoetXavier RogiersRoberto TroisiBernard de HemptinneRaymond VanholderIsabelle Colle

A1 Journal Article in LIVER TRANSPLANTATION

Improved results for adult split liver transplantation with extended right lobe grafts: could we enhance its application (vol 41, pg 3485, 2009)

EVA-LINE DECOSTERRoberto TroisiMAURICIO SAINZ-BARRIGAIVO HAENTJENSLUC COLENBIEAnja GeertsIsabelle ColleHans Van VlierbergheBernard de HemptinneXavier Rogiers

Kinetics of angiogenic changes in a new mouse model for hepatocellular carcinoma

Femke HeindryckxKoen MertensNicolas CharetteBert VandeghinsteChristophe CasteleynChristophe Van SteenkisteDominique SlaetsLouis LibbrechtSteven StaelensPeter Starkel et al.

A1 Journal Article in MOLECULAR CANCER

Liver transplantation for alcoholic liver disease: a retrospective analysis of recidivism, survival and risk factors predicting to alcohol relapse

Elise DeruytterChristophe Van SteenkisteAnja GeertsHans Van VlierbergheFrederik BerrevoetBernard de HemptinneXavier RogiersRoberto TroisiIsabelle Colle

LTx for alcoholic liver disease: a retrospective analysis of recidivism, survival and risk factors predisposing to alcohol relapse

Elise DeruytterChristophe Van SteenkisteAnja GeertsHans Van VlierbergheFrederik BerrevoetBernard de HemptinneXavier RogiersRoberto TroisiIsabelle Colle

Measurement of porto-systemic shunting in mice by novel three-dimensional micro-single photon emission computed tomography imaging enabling longitudinal follow-up

Christophe Van SteenkisteSteven StaelensSteven DeleyeFilip De VosStefaan VandenbergheAnja GeertsChristophe Van De WieleMartine De VosHans Van VlierbergheIsabelle Colle

A1 Journal Article in LIVER INTERNATIONAL

Multicenter Belgian survey on liver transplantation for hepatocellular failure after bilio-pancreatic diversion (Scopinaro operation) for weight loss

Anja GeertsTom DariusThiery ChapelleGeert RoeyenRaymond AertsSven FrancqueTania RoskamsLouis LibbrechtFrederik NevensJacques Pirenne et al.

N-Glycosylation patterns of serum proteins to make the distinction between steatosis of the liver and non-alcoholic steatohepatitis in obese patients scheduled for bariatric surgery

BRAM BLOMMELouis LibbrechtPiet PattynYves Van NieuwenhoveDirk Van de PutteAnja GeertsIsabelle ColleN CallewaertHans Van Vlierberghe

Presence of liver angiogenesis and upregulation of the vascular endothelial growth factor (VEGF) in a mice model of non-alcoholic steatohepatitis (NASH)

Stephanie CoulonAnja GeertsBram BrouwersDennis VlaeminckLouis LibbrechtChristophe Van SteenkisteFemke HeindryckxHans Van VlierbergheIsabelle Colle

Presence of liver angiogenesis and upregulation of VEGF in a mouse mice of non-alkoholic steatohepatitis (NASH)

Stephanie CoulonAnja GeertsChristophe CasteleynFemke HeindryckxChristophe Van SteenkisteLouis LibbrechtHans Van VlierbergheIsabelle Colle

Subfulminant hepatitis B during treatment with adalimumab in a patient with rheumatoid arthritis and chronic hepatitis B

Xavier VerhelstHans OrlentIsabelle ColleAnja GeertsMartine De VosHans Van Vlierberghe

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

The multicenter Belgian survey on liver transplantation for hepatocellular failure after Bariatric surgery

Anja GeertsT DariusT ChapelleG RoeyenS FrancqueLouis LibbrechtF NevensJ PirenneRoberto Troisi

A1 Journal Article in TRANSPLANTATION PROCEEDINGS

Vascular corrosion casting: analyzing wall shear stress in the portal vein and vascular abnormalities in portal hypertensive and cirrhotic rodents

Christophe Van SteenkisteBram TrachetChristophe CasteleynDenis Van LooLuc Van HoorebekePatrick SegersAnja GeertsHans Van VlierbergheIsabelle Colle

A1 Journal Article in LABORATORY INVESTIGATION

2009

ADULT SPLIT LIVER TRANSPLANTATION WITH eRLG FROM EXTENDED CRITERIA DONORS UNDER MELD PATIENT ALLOCATION

MAURICIO SAINZ-BARRIGAEVA-LINE DECOSTERIVO HAENTJENSLUC COLENBIEAnja GeertsIsabelle ColleHans Van VlierbergheFrederik BerrevoetBernard de HemptinneRoberto Troisi et al.

Deficiency in Placental Growth Factor improves inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic mice

Christophe Van SteenkisteAnja GeertsJordi RiberaSonia TuguesManuel Morales-RuizJean Marie StassenPeter CarmelietEkhart VerdegemLouis LibbrechtMartine De Vos et al.

Development of the hepatopulmonary syndrome in mice is accompanied with pulmonary angiogenesis

Christophe Van SteenkisteMarjan WaterloosAnja GeertsChristophe CasteleynFilip De VosMartine De VosHans Van VlierbergheIsabelle Colle

MELD ALLOCATION SYSTEM IN BELGIUM-ET AND OUTCOME

MAURICIO SAINZ-BARRIGAIVO HAENTJENSEVA-LINE DECOSTERLUC COLENBIEBERT VAN DEN BOSSCHEFrederik BerrevoetAnja GeertsIsabelle ColleHans Van VlierbergheXavier Rogiers et al.

Role of Placental Growth Factor in Mesenteric Neoangiogenesis in a Mouse Model of Portal Hypertension

Christophe Van SteenkisteAnja GeertsEline VanheuleHans Van VlierbergheFilip De VosKim OlievierChristophe CasteleynDebby LaukensMartine De VosJean-Marie Stassen et al.

A1 Journal Article in GASTROENTEROLOGY

2008

An intravital microscopic study of the hepatic microcirculation in cirrhotic mice models: relationship between fibrosis and angiogenesis

Eline VanheuleAnja GeertsJacques Van HuysseDaphné SchelfhoutMarleen PraetHans Van VlierbergheMartine De VosIsabelle Colle

A1 Journal Article in INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Comparison of three research models of portal hypertension in mice: macroscopic, histological and portal pressure evaluation

Anja GeertsEline VanheuleMarleen PraetHans Van VlierbergheMartine De VosIsabelle Colle

A1 Journal Article in INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Deficiency in placental growth factor causes a decreased porto-systemic collateral vessel formation in portal hypertensive mice

Christophe Van SteenkisteAnja GeertsEline VanheuleHans Van VlierbergheFilip De VosPeter CarmelietMartine De VosIsabelle Colle

Deficiency in placental growth factor causes a decreased porto-systemic collateral vessel formation in portal hypertensive mice

Christophe Van SteenkisteAnja GeertsEline VanheuleHans Van VlierbergheFilip De VosMartine De VosIsabelle Colle

Deficiency in placental growth factor causes a decreased portosystemic collateral vessel information in portal hypertensive mice

Christophe Van SteenkisteAnja GeertsEline VanheuleHans Van VlierbergheFilip De VosPeter CarmelietMartine De VosIsabelle Colle

Development of cirrhosis is associated with increased levels of placental growth factor

Christophe Van SteenkisteBen SchroyenAnja GeertsEline VanheuleHans Van VlierbergheDebby LaukensKim OlievierHendrik ReynaertMartine De VosIsabelle Colle

Development of cirrhosis is associated with increased levels of placental growth factor: a descriptive study

Christophe Van SteenkisteBen SchroyenAnja GeertsEline VanheuleHans Van VlierbergheDebby LaukensKim OlievierHendrik ReynaertAlbert GeertsPeter Carmeliet et al.

Development of cirrhosis is associated with increased levels of placental growth factor: a descriptive study

Christophe Van SteenkisteBen SchroyenAnja GeertsEline VanheuleHans Van VlierbergheDebby LaukensKim OlievierHendrik ReynaertAlbert GeertsPeter Carmeliet et al.

Hemodynamic changes in splanchnic blood vessels in portal hypertension

Isabelle ColleAnja GeertsChristophe Van SteenkisteHans Van Vlierberghe

A1 Journal Article in ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY

Influence of bosentan on liver microcirculation in an experimental mouse model of cirrhosis studied by intravital microscopy

Eline VanheuleFREDERIK DE CLERCKChristophe Van SteenkisteAnja GeertsHans Van VlierbergheMartine De VosIsabelle Colle

Influence of bosentan on liver microcirculation in an experimental mouse model of cirrhosis studied by intravital microscopy

Eline VanheuleFREDERIK DE CLERCKChristophe Van SteenkisteAnja GeertsHans Van VlierbergheMartine De VosIsabelle Colle

Influence of non-selective and selective endothelin - 1 receptor antagonists on liver microcirculation in an experimental mouse model of cirrhosis studied by intravital fluorescence microscopy

Eline VanheuleChristophe Van SteenkisteAnja GeertsHans Van VlierbergheMartine De VosIsabelle Colle

Influence of non-selective and selective endothelin-1 receptor antagonists on liver microcirculation in an experimental mouse model of cirrhosis studied by intravital microscopy

Eline VanheuleChristophe Van SteenkisteAnja GeertsHans Van VlierbergheMartine De VosIsabelle Colle

Influence of somatostatin and octreotide on liver microcirculation in an experimental mouse model of cirrhosis studied by intravital fluorescence microscopy

Eline VanheuleAnja GeertsHendrik ReynaertHans Van VlierbergheAlbert GeertsMartine De VosIsabelle Colle

A1 Journal Article in LIVER INTERNATIONAL

Influence of somatostatin and octreotide on liver microcirculation in an experimental mouse model of cirrhosis studied by intravital fluorescence microscopy (vol 28, pg 107, 2008)

Eline VanheuleAnja GeertsHendrik ReynaertHans Van VlierbergheAlbert GeertsMartine De VosIsabelle Colle

Proteomic analysis to identify the pathophysiological role of placental growth factor (Plgf) in hepatic stellate cell function and cirrhosis

Jordi RiberaSonia TuguesMontserrat PautaAnja GeertsChristophe Van SteenkisteIsabelle CollePeter CarmelietVicente ArroyoWladimiro JiménezManuel Morales-Ruiz

Rapamycin prevents mesenteric neo-angiogenesis and reduces splanchnic blood flow in portal hypertensive mice

Anja GeertsEline VanheuleHans Van VlierbergheLuc LeybaertChristophe Van SteenkisteMartine De VosIsabelle Colle

A1 Journal Article in HEPATOLOGY RESEARCH

The use of antibodies against the placental growth factor as a new therapeutic target in the pathophysiology of portal hypertensive mice

Christophe Van SteenkisteAnja GeertsEline VanheuleHans Van VlierbergheFilip De VosPeter CarmelietMartine De VosJean-Marie StassenDésiré CollenIsabelle Colle

The use of antibodies against the placental growth factor in the prophylactic and therapeutic setting in portal hypertensive mice

Christophe Van SteenkisteAnja GeertsEline VanheuleHans Van VlierbergheFilip De VosPeter CarmelietMartine De VosJean-Marie StassenDésiré CollenIsabelle Colle

The use of antibodies against the placental growth factor in the prophylactic setting in the pathophysiology of portal hypertensive mice

Christophe Van SteenkisteAnja GeertsEline VanheuleHans Van VlierbergheFilip De VosPeter CarmelietMartine De VosJean-Marie StassenDésiré CollenIsabelle Colle

2007

Angiogenesis in portal hypertension: Involvement in increased splanchnic blood flow and collaterals?

Anja GeertsIsabelle Colle

Editorial material

Decreased leukocyte recruitment in the mesenteric microcirculation of rats with cirrhosis is partially restored by treatment with peginterferon: an in vivo study

Anja GeertsKin Jip CheungHans Van VlierbergheAn De VrieseSiska MortierEline VanheuleNorbert LameireMartine De VosIsabelle Colle

A1 Journal Article in JOURNAL OF HEPATOLOGY

Development of cirrhosis is associated with increased angiogenesis in the liver

Anja GeertsEline VanheuleChristophe Van SteenkisteHans Van VlierbergheMartine De VosIsabelle Colle

Development of cirrhosis is associated with increased angiogenesis in the liver

Anja GeertsEline VanheuleChristophe Van SteenkisteHans Van VlierbergheMartine De VosIsabelle Colle

Development of cirrhosis is associated with increased angiogenesis in the liver: study of the expression of vascular endothelial growth factors

Eline VanheuleChristophe Van SteenkisteAnja GeertsKOEN DECUYPEREHans Van VlierbergheMartine De VosIsabelle Colle

Hepatopulmonary syndrome and portopulmonary hypertension : what's new?

Isabelle ColleChristophe Van SteenkisteAnja GeertsHans Van Vlierberghe

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Intravital microscopy study of the development of cirrhosis in CBDL and CCl4 mice models

Eline VanheuleAnja GeertsMarleen PraetChristophe Van SteenkisteHans Van VlierbergheMartine De VosIsabelle Colle

One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus

M Van OnnaAnja GeertsHans Van VlierbergheR BerrevoetBernard de HemptinneRoberto TroisiIsabelle Colle

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

The role of splanchnic microcirculatory disturbances in portal hypertension and cirrhosis

Anja GeertsIsabelle ColleMartine De Vos

The time-dependent release of angiogenetic factors in the splanchnic microvasculature in portal hypertension

Christophe Van SteenkisteAnja GeertsEline VanheuleHans Van VlierbergheMartine De VosIsabelle Colle

2006

Increased angiogenesis and permeability in the mesenteric microvasculature of rats with cirrhosis and portal hypertension: an in vivo study

Anja GeertsAn De VrieseEline VanheuleHans Van VlierbergheSiska MortierKin Jip CheungPieter DemetterNorbert LameireMartine De VosIsabelle Colle

A1 Journal Article in LIVER INTERNATIONAL

Influence of somatostatin and octreotide on liver microcirculation in an experimental mouse model of cirrhosis studied by intravital fluorescence microscopy

Eline VanheuleAnja GeertsHendrik ReynaertHans Van VlierbergheAlbert GeertsMartine De VosIsabelle Colle

Influence of somatostatin and octreotide on liver microcirculation in an experimental mouse model of cirrhosis studied by intravital microscopy

Eline VanheuleAnja GeertsHendrik ReynaertHans Van VlierbergheAlbert GeertsMartine De VosIsabelle Colle

Placental growth factor plays a role in the mesenteric neo-angiogenesis of portal hypertensive mice

Anja GeertsEline VanheuleP CARMELIETHans Van VlierbergheLuc LeybaertMartine De VosIsabelle Colle

Placental growth factor plays a role in the mesenteric neo-angiogenesis of portal hypertensive mice

Anja GeertsEline VanheuleP CARMELIETHans Van VlierbergheLuc LeybaertMartine De VosIsabelle Colle

2005

In vivo vascular hyporeactivity in the mesenteric artery of rats with cirrhosis: reversed by chronic octreotide LAR administration

Isabelle ColleAnja GeertsAn De VrieseHans Van VlierbergheNorbert LameireJohan Van de VoordeMartine De Vos

2004

Decreased leukocyte recruitment in the peritoneal microcirculation of rats with portal hypertension: role of L-selectin?

Anja GeertsIsabelle ColleAn De VrieseSiska MortierHans Van VlierbergheNorbert LameireMartine De Vos

Increased angiogenesis and permeabiliy in the peritoneal microcirculation of rats with portal hypertension and cirrhosis

Anja GeertsIsabelle ColleAn De VrieseSiska MortierHans Van VlierbergheNorbert LameireMartine De Vos

Metastatic follicular dendritic cell sarcoma of the stomach: A case report and review of the literature

Anja GeertsE LAGAEK DHAENEMarc PeetersAnouk WaeytensPieter DemetterClaude CuvelierLuc DefreyneMartine De VosPiet Pattyn

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

2003

Een enterovaginale fistel secundair aan een geperforeerd Meckel's diverticulitis

Anja GeertsIsabelle ColleHans Van VlierbergheMartine De Vos

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Follicular dendritic cell sarcoma of the stomach: case report and review of the literature

Pieter DemetterAnja GeertsE LAGAEK DHAENEMarc PeetersAnouk WaeytensLuc DefreyneMartine De VosPiet PattynClaude Cuvelier