Research Explorer

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Researcher

Ana Alejandra Barrera Jiménez

Awards & Distinctions

13 Results

2024

Analysis of the effect of formulation properties and process parameters on granule formation in twin-screw wet granulation

Michiel PeetersAna Alejandra Barrera JiménezKensaku MatsunamiMichael GhijsEduardo dos Santos SchultzMina RoudgarTamas VighFanny StaufferIngmar NopensThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

2023

Evaluation of the influence of material properties and process parameters on granule porosity in twin-screw wet granulation

Michiel PeetersAna Alejandra Barrera JiménezKensaku MatsunamiFanny StaufferIngmar NopensThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Exploring the effect of raw material properties on continuous twin-screw wet granulation manufacturability

Michiel PeetersAna Alejandra Barrera JiménezKensaku MatsunamiDaan Van HauwermeirenFanny StaufferLærke ArnfastTamas VighIngmar NopensThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Linking material properties to 1D-PBM parameters towards a generic model for twin-screw wet granulation

Ana Alejandra Barrera JiménezKensaku MatsunamiDaan Van HauwermeirenMichiel PeetersFanny StaufferEduardo dos Santos SchultzAshish KumarThomas De BeerIngmar Nopens

A1 Journal Article in CHEMICAL ENGINEERING RESEARCH & DESIGN

Model development and calibration of two-dimensional population balance model for twin-screw wet granulation based on particle size distribution and porosity

Ana Alejandra Barrera JiménezKensaku MatsunamiMichael GhijsDaan Van HauwermeirenMichiel PeetersFanny StaufferThomas De BeerIngmar Nopens

A1 Journal Article in POWDER TECHNOLOGY

Partial least squares regression to calculate population balance model parameters from material properties in continuous twin-screw wet granulation

Ana Alejandra Barrera JiménezKensaku MatsunamiDaan Van HauwermeirenMichiel PeetersFanny StaufferEduardo dos Santos SchultzAshish KumarThomas De BeerIngmar Nopens

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Validation of model-based design of experiments for continuous wet granulation and drying

Kensaku MatsunamiTuur VandeputteAna Alejandra Barrera JiménezMichiel PeetersMichael GhijsDaan Van HauwermeirenFanny StaufferEduardo dos Santos SchultzIngmar NopensThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

2022

In-depth analysis of the impacts of material properties on size distributions in continuous twin-screw wet granulation to construct a generic 1D population balance model

Kensaku MatsunamiAna Alejandra Barrera JiménezMichiel PeetersDaan Van HauwermeirenThomas De BeerIngmar Nopens

Increasing the applicability of population balance models in continuous pharmaceutical twin-screw wet granulation

Ana Alejandra Barrera JiménezIngmar NopensThomas De BeerDaan Van Hauwermeiren

Model-based design of experiments in drug product development in continuous manufacturing

Tuur VandeputteAna Alejandra Barrera JiménezKensaku MatsunamiMichiel PeetersMichael GhijsDaan Van HauwermeirenIngmar NopensThomas De Beer

Towards a generic population balance model for twin-screw wet granulation : from material properties to particle size distribution

Ana Alejandra Barrera JiménezDaan Van HauwermeirenKensaku MatsunamiMichiel PeetersThomas De BeerIngmar Nopens

Two-dimensional population balance model for twin-screw wet granulation : model development and calibration based on particle size distribution and porosity

Kensaku MatsunamiAna Alejandra Barrera JiménezMichiel PeetersMichael GhijsDaan Van HauwermeirenThomas De BeerIngmar Nopens

2021

Improvement of a 1D population balance model for twin-screw wet granulation by using identifiability analysis

Ana Alejandra Barrera JiménezDaan Van HauwermeirenMichiel PeetersThomas De BeerIngmar Nopens

A1 Journal Article in PHARMACEUTICS