Research Explorer

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Researcher

An Staes

Awards & Distinctions

74 Results

2023

CysQuant : simultaneous quantification of cysteine oxidation and protein abundance using data dependent or independent acquisition mass spectrometry

Jingjing HuangAn StaesFrancis ImpensVadim DemichevFrank Van BreusegemKris GevaertPatrick Willems

A1 Journal Article in REDOX BIOLOGY

N-terminal proteoforms may engage in different protein complexes

Annelies BogaertDaria FijalkowskaAn StaesTessa Van de SteeneMarnik VuylstekeCharlotte StadlerSven EyckermanKerstin SpirohnTong HaoMichael A Calderwood et al.

A1 Journal Article in LIFE SCIENCE ALLIANCE

Protein interactors of 3-O sulfated heparan sulfates in human MCI and age-matched control cerebrospinal fluid

Andreia Sofia da Costa de Monica FerreiraEvy TimmermanAn StaesMarnik VuylstekeLouis De MuynckKris Gevaert

A1 Journal Article in SCIENTIFIC DATA

α-1,6-fucosyltransferase plays a critical role during embryogenesis of the hemimetabolous insect Nilaparvata lugens

Qun YangGuy SmaggheAn StaesKris GevaertKristof De Schutter

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

2022

A strong cation exchange chromatography protocol for examining N-terminal proteoforms

Esperanza FernándezAnnelies BogaertEvy TimmermanAn StaesFrancis ImpensKris Gevaert

Bookchapter in Yeast functional genomics : methods and protocols

Limited evidence for protein products of non-coding transcripts in the HEK293T cellular cytosol

Annelies BogaertDaria FijalkowskaAn StaesTessa Van de SteeneHans DemolKris Gevaert

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets

Laura Van MoortelJonathan ThommisBrecht MaertensAn StaesDorien ClarisseDelphine De SutterClaude LibertOnno C. MeijerSven EyckermanKris Gevaert et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

RNAi of Mannosidase‐Ia in the Colorado potato beetle and changes in the midgut and peritrophic membrane

Dongdong LiuKristof De SchutterJohann FarAn StaesKoen DewettinckLoic QuintonKris GevaertGuy Smagghe

A1 Journal Article in PEST MANAGEMENT SCIENCE

Triazolinedione protein modification : from an overlooked off-target effect to a tryptophan-based bioconjugation strategy

Klaas DecoeneKamil ÜnalAn StaesOlivier ZwaenepoelJan GettemansKris GevaertJohan WinneAnnemieke Madder

A1 Journal Article in CHEMICAL SCIENCE

2021

Use of hybrid data-dependent and -independent acquisition spectral libraries empowers dual-proteome profiling

Patrick WillemsUrsula FelsAn StaesKris GevaertPetra Van Damme

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

2020

N-glycosylation site analysis reveals sex-related differences in protein N-glycosylation in the rice brown planthopper (Nilaparvata lugens)

Freja ScheysEls Van DammeJarne PauwelsAn StaesKris GevaertGuy Smagghe

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Removing the hidden data dependency of DIA with predicted spectral libraries

Bart Van PuyveldeSander WillemsRalf GabrielsSimon DaledLaura De ClerckSofie Vande CasteeleAn StaesFrancis ImpensDieter DeforceLennart Martens et al.

A1 Journal Article in PROTEOMICS

Simple peptide quantification approach for MS-based proteomics quality control

Teresa MaiaAn StaesKim PlasmanJarne PauwelsKatie BoucherAndrea ArgentiniLennart MartensTony MontoyeKris GevaertFrancis Impens

A1 Journal Article in ACS OMEGA

2019

An update on the moFF algorithm for label-free quantitative proteomics

Andrea ArgentiniAn StaesBjörn Andreas GrüningSubina MehtaCaleb EasterlyTimothy GriffinPratik JagtapFrancis ImpensLennart Martens

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides

Tim HanderÁlvaro Daniel Fernández FernándezRobert KumpfPatrick WillemsHendrik SchatowitzDebbie RombautAn StaesJonah NolfRobin PottiePanfeng Yao et al.

A1 Journal Article in SCIENCE

Disruption of endocytosis through chemical inhibition of clathrin heavy chain function

Wim DejongheIsha SharmaBram DenooSteven De MunckQing LuKiril MishevHaydar BulutEvelien MylleRiet De RyckeMina Vasileva et al.

A1 Journal Article in NATURE CHEMICAL BIOLOGY

Salmonella Typhi, Paratyphi A, Enteritidis and Typhimurium core proteomes reveal differentially expressed proteins linked to the cell surface and pathogenicity

Sara SalehSandra Van PuyveldeAn StaesEvy TimmermanBarbara BarbéJan JacobsKris GevaertStijn Deborggraeve

A1 Journal Article in PLOS NEGLECTED TROPICAL DISEASES

Targeted proteomics for studying pathogenic bacteria

Sara SalehAn StaesStijn DeborggraeveKris Gevaert

A1 Journal Article in PROTEOMICS

2018

Chronic kidney disease circulating calciprotein particles and extracellular vesicles promote vascular calcification : a role for GRP (Gla-rich protein)

Carla SB ViegasLúcia SantosAnjos L MacedoAntónio A MatosAna P SilvaPedro L NevesAn StaesKris GevaertRute MoraisCees Vermeer et al.

A1 Journal Article in ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Evolutionarily conserved and species-specific glycoproteins in the N-glycoproteomes of diverse insect species

Freja ScheysEls Van DammeKristof De SchutterAn StaesKris GevaertGuy Smagghe

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Impairment of angiogenesis by fatty acid synthase inhibition involves mTOR malonylation

Ulrike BruningFrancisco Morales-RodriguezJoanna KaluckaJermaine GoveiaFederico TavernaKarla CS QueirozCharlotte DuboisAnna Rita CantelmoRongyuan ChenStefan Loroch et al.

A1 Journal Article in CELL METABOLISM

2017

Expanding the interactome of TES by exploiting TES modules with different subcellular localizations

Stefano SalaMarleen Van TroysSandrine MedvesMarie CatillonEvy TimmermanAn StaesElisabeth Schaffner-ReckingerKris GevaertChristophe Ampe

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Protease substrate profiling by N-terminal COFRADIC

An StaesPetra Van DammeEvy TimmermanBart RuttensElisabeth StesKris GevaertFrancis Impens

Bookchapter in Protein terminal profiling : methods and protocols

Quality control in mass spectrometry-based proteomics

Wout BittremieuxDavid L TabbFrancis ImpensAn StaesEvy TimmermanLennart MartensKris Laukens

A1 Journal Article in MASS SPECTROMETRY REVIEWS

2016

An extra dimension in protein tagging by quantifying universal proteotypic peptides using targeted proteomics

Giel VandemoorteleAn StaesGiulia GonnelliNoortje SamynDelphine De SutterElien VandermarliereEvy TimmermanKris GevaertLennart MartensSven Eyckerman

A1 Journal Article in SCIENTIFIC REPORTS

CEP5 and XIP1/CEPR1 regulate lateral root initiation in Arabidopsis

Ianto RobertsStephanie SmithElisabeth StesBert De RybelAn StaesBrigitte Van De CotteMaria NjoLise DedeyneHans DemolJulien Lavenus et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

De novo design of a biologically active amyloid

Rodrigo GallardoMeine RamakersFrederik De SmetFilip ClaesLadan KhodaparastLaleh KhodaparastJosé R CouceiroTobias LangenbergMaxime SiemonsSofie Nyström et al.

A1 Journal Article in SCIENCE

Protein aggregation as an antibiotic design strategy

Natalia G BednarskaJohan van EldereRodrigo GallardoAshok GanesanMeine RamakersIsabel VogelPieter BaatsenAn StaesMarc GoethalsPer Hammarström et al.

A1 Journal Article in MOLECULAR MICROBIOLOGY

The Arabidopsis iron-sulfur protein GRXS17 is a target of the ubiquitin E3 ligases RGLG3 and RGLG4

Astrid Nagels DurandSabrina IñigoAndrés Ritter TraubElisa IniestoRebecca De ClercqAn StaesJelle Van LeeneVicente RubioKris GevaertGeert De Jaeger et al.

A1 Journal Article in PLANT AND CELL PHYSIOLOGY

The response of the root proteome to the synthetic strigolactone GR24 in Arabidopsis

Alan WaltonElisabeth StesGeert GoeminneLukas BraemMarnik VuylstekeCedrick MatthysCarolien De CuyperAn StaesJonathan VandenbusscheFrançois-Didier Boyer et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Zebrafish collagen type I: molecular and biochemical characterization of the major structural protein in bone and skin

Charlotte GistelinckR GioiaA GagliardiF TonelliL MarcheseL BianchiC LandiL BiniAnn HuysseunePaul Witten et al.

A1 Journal Article in SCIENTIFIC REPORTS

moFF : a robust and automated approach to extract peptide ion intensities

Andrea ArgentiniLudger GoeminneKenneth VerheggenNiels HulstaertAn StaesLieven ClementLennart Martens

A1 Journal Article in NATURE METHODS

2015

GRIM REAPER peptide binds to receptor kinase PRK5 to trigger cell death in Arabidopsis

Michael WrzaczekJulia P VainonenSimon StaelStyliani TsiatsianiHanna Help-Rinta-RahkoAdrien GauthierDavid KaufholdtBenjamin BollhönerAiri LamminmäkiAn Staes et al.

A1 Journal Article in EMBO JOURNAL

Open-source, platform-independent library and online scripting environment for accessing thermo scientific RAW files

Pieter KelchtermansAna Sílvia Ferreira Diamantino Coelho e SilvaAndrea ArgentiniAn StaesJonathan VandenbusscheKris LaukensDirk ValkenborgLennart Martens

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Study of protein expresion [sic] in peri-infarct tissue after cerebral ischemia

David BreaJesús AgullaAn StaesKris GevaertFrancisco CamposTomás SobrinoMiguel BlancoAntoni DávalosJosé CastilloPedro Ramos-Cabrer

A1 Journal Article in SCIENTIFIC REPORTS

2014

qcML: an exchange format for quality control metrics from mass spectrometry experiments

Mathias WalzerLucia Espona PernasSara NassoWout BittremieuxSven NahnsenPieter KelchtermansPeter PichlerHenk WP van den ToornAn StaesJonathan Vandenbussche et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

2013

Asn₃, a reliable, robust, and universal lock mass for improved accuracy in LC-MS and LC-MS/MS

An StaesJonathan VandenbusscheHans DemolMarc GoethalsSule Yilmaz-RumpfNiels HulstaertSven DegroevePieter KelchtermansLennart MartensKris Gevaert

A1 Journal Article in ANALYTICAL CHEMISTRY

Early targets of MIR-34A in neuroblastoma

P De AntonellisM CarotenutoG De VitaJonathan VandenbusscheC MedagliaJ VandesopeleP MestdaghLennart MartensAn StaesKathleen Moens et al.

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF

Roosmarijn VandenbrouckeEline DejonckheereFilip Van HauwermeirenSofie LodensRiet De RyckeElien Van WonterghemAn StaesKris GevaertCarlos López-OtinClaude Libert

A1 Journal Article in EMBO MOLECULAR MEDICINE

Proteomic and metabolomic responses to connexin43 silencing in primary hepatocyte cultures

Mathieu VinkenMichaël MaesRachel CavillDirk ValkenborgJames K EllisElke DecrockLuc LeybaertAn StaesKris GevaertAndré G Oliveira et al.

A1 Journal Article in ARCHIVES OF TOXICOLOGY

SCX charge state selective separation of tryptic peptides combined with 2D-RP-HPLC allows for detailed proteome mapping

Lazaro H BetancourtPieter-Jan De BockAn StaesEvy TimmermanYasset Perez-RiverolAniel SanchezVladimir BesadaLuis Javier GonzalezJoël VandekerckhoveKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOMICS

The Arabidopsis METACASPASE9 degradome

Styliani TsiatsianiEvy TimmermanPieter-Jan De BockDominique VercammenSimon StaelBrigitte Van De CotteAn StaesMarc GoethalsTine BeunensPetra Van Damme et al.

A1 Journal Article in PLANT CELL

2012

A catalogue of putative HIV-1 protease host cell substrates

Francis ImpensEvy TimmermanAn StaesKathleen MoensKevin AriënBruno VerhasseltJoël VandekerckhoveKris Gevaert

A1 Journal Article in BIOLOGICAL CHEMISTRY

Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity

Davina TondeleirAnja LambrechtsMatthias MüllerVeronique JonckheereThierry DollDrieke VandammeKarima BakkaliDavy WaterschootMarianne LemaistreOlivier Debeir et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Chromatographic retention time prediction for posttranslationally modified peptides

Luminita MoruzAn StaesJoseph M FosterMaria HatzouEvy TimmermanLennart MartensLukas Käll

A1 Journal Article in PROTEOMICS

How many spots with missing values can be tolerated in quantitative two-dimensional gel electrophoresis when applying univariate statistics?

Maria ZellnerAlexandra GrafSonja ZehetmayerWolfgang WinklerAn StaesKris GevaertJoël VandekerckhoveMartina Marchetti-DeschmannIngrid MillerPeter Bauer et al.

A1 Journal Article in JOURNAL OF PROTEOMICS

The effect of peptide identification search algorithms on MS2-based label-free protein quantification

Sven DegroeveAn StaesPieter-Jan De BockLennart Martens

A1 Journal Article in OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

2011

Combining quantitative proteomics data processing workflows for greater sensitivity

Niklaas ColaertChristophe Van HueleSven DegroeveAn StaesJoël VandekerckhoveKris GevaertLennart Martens

A1 Journal Article in NATURE METHODS

Selecting protein N-terminal peptides by combined fractional diagonal chromatography

An StaesFrancis ImpensPetra Van DammeBart RuttensMarc GoethalsHans DemolEvy TimmermanJoël VandekerckhoveKris Gevaert

A1 Journal Article in NATURE PROTOCOLS

cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)

Mathieu BertrandSaskia LippensAn StaesBarbara GilbertRia RoelandtJelle De MedtsKris GevaertWim DeclercqPeter Vandenabeele

A1 Journal Article in PLOS ONE

2010

Complementary positional proteomics for screening substrates of endo- and exoproteases

Petra Van DammeAn StaesSilvia BronsomsKenny HelsensNiklaas ColaertEvy TimmermanFrancesc X AvilesJoël VandekerckhoveKris Gevaert

A1 Journal Article in NATURE METHODS

ms_lims, a simple yet powerful open source laboratory information management system for MS-driven proteomics

Kenny HelsensNiklaas ColaertHarald BarsnesThilo MuthKristian FlikkaAn StaesEvy TimmermanSteffi WortelkampAlbert SickmannJoël Vandekerckhove et al.

A1 Journal Article in PROTEOMICS

2009

A review of COFRADIC techniques targeting protein N-terminal acetylation

Petra Van DammeJozef Van DammeHans DemolAn StaesJoël VandekerckhoveKris Gevaert

Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains

T WakabayashiK CraessaertsL BammensM BentahirF BorgionsP HerdewijnAn StaesEvy TimmermanJoël VandekerckhoveE Rubinstein et al.

A1 Journal Article in NATURE CELL BIOLOGY

Identification and Functional Characterization of N-Terminally Acetylated Proteins in Drosophila melanogaster

S GoetzeE QeliC MosimannAn StaesB GerritsB RoschitzkiS MohantyEM NiedererE LaczkoEvy Timmerman et al.

A1 Journal Article in PLOS BIOLOGY

2008

Improved recovery of proteome-informative, protein N-terminal peptides by combined fractional diagonal chromatography (COFRADIC)

An StaesPetra Van DammeKenny HelsensHans DemolJoël VandekerckhoveKris Gevaert

A1 Journal Article in PROTEOMICS

Multiple isoforms of the tumor suppressor myopodin are simultaneously transcribed in cancer cells

Ariane De GanckVeerle De CorteAn StaesKris GevaertJoël VandekerckhoveJan Gettemans

A1 Journal Article in BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Tandem PDZ Protein Syntenin Interacts with the Aminoacyl tRNA Synthetase Complex in a Lysyl-tRNA Synthetase-Dependent Manner

Kris MeerschaertEline RemueAriane De GanckAn StaesCiska BoucherieKris GevaertJoël VandekerckhoveLawrence KleimanJan Gettemans

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

2007

A new approach for mapping sialylated N-glycosites in serum proteomes

Bart GhesquièreLien BuylHans DemolJozef Van DammeAn StaesEvy TimmermanJoël VandekerckhoveKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Assessing a novel microfluidic interface for shotgun proteome analyses

An StaesEvy TimmermanI VAN DAMMEKenny HelsensJoël VandekerckhoveM VOLLMERKris Gevaert

A1 Journal Article in JOURNAL OF SEPARATION SCIENCE

Large-scale identification of N-terminal peptides in the halophilic archaea Halobacterium salinarum and Natronomonas pharaonis

Michalis AivaliotisKris GevaertMichaela FalbAndreas TebbeKosta KonstantinidisBirgit BisleChristian KleinLennart MartensAn StaesEvy Timmerman et al.

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

2006

A new functional, chemical proteomics technology to identify purine nucleotide binding sites in complex proteomes

Xavier HanoulleJozef Van DammeAn StaesLennart MartensMarc GoethalsJoël VandekerckhoveKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Four stage liquid chromatographic selection of methionyl peptides for peptide-centric proteome analysis: the proteome of human multipotent adult progenitor cells

Kris GevaertJozef PinxterenHans DemolKoen HugelierAn StaesJozef Van DammeLennart MartensJoël Vandekerckhove

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Improved tandem mass spectrometric characterization of 3-nitrotyrosine sites in peptides

Bart GhesquièreMarc GoethalsJozef Van DammeAn StaesEvy TimmermanJoël VandekerckhoveKris Gevaert

A1 Journal Article in RAPID COMMUNICATIONS IN MASS SPECTROMETRY

2005

Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis

Petra Van DammeLennart MartensJozef Van DammeKoen HugelierAn StaesJoël VandekerckhoveKris Gevaert

A1 Journal Article in NATURE METHODS

Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC

Kris GevaertAn StaesJozef Van DammeSara De GrootKoen HugelierHans DemolLennart MartensMarc GoethalsJoël Vandekerckhove

A1 Journal Article in PROTEOMICS

The human platelet proteome mapped by peptide-centric proteomics: a functional protein profile

Lennart MartensPetra Van DammeJozef Van DammeAn StaesEvy TimmermanBart GhesquièreGrégoire R ThomasJoël VandekerckhoveKris Gevaert

A1 Journal Article in PROTEOMICS

2004

Global differential non-gel proteomics by quantitative and stable labeling of tryptic peptides with oxygen-18

An StaesHans DemolJozef Van DammeLennart MartensJoël VandekerckhoveKris Gevaert

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Reversible labeling of cysteine-containing peptides allows their specific chromatographic isolation for non-gel proteome studies

Kris GevaertBart GhesquièreAn StaesLennart MartensJozef Van DammeGrégoire ThomasJoël Vandekerckhove

A1 Journal Article in PROTEOMICS

Selective contribution of eukaryotic prefoldin subunits to actin and tubulin binding

CT SIMONSAn StaesHeidi RommelaereChristophe AmpeSA LEWISNJ COWAN

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2003

Activation-associated secreted proteins are the most abundant antigens in a host protective fraction from Ostertagia ostertagi

Peter GeldhofIsabel VercauterenKris GevaertAn StaesDP KNOXJoël VandekerckhoveJozef VercruysseEdwin Claerebout

A1 Journal Article in MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides

Kris GevaertMarc GoethalsLennart MartensJozef Van DammeAn StaesGrégoire ThomasJoël Vandekerckhove

A1 Journal Article in NATURE BIOTECHNOLOGY

IL-29 Is proteomics heading towards medicine?

Joël VandekerckhoveJozef Van DammeLennart MartensGrégoire ThomasAn StaesMarc GoethalsBart GhesquièreMagda PuypeHans DemolKris Gevaert

A2 Journal Article in PIGMENT CELL RESEARCH

2002

Chromatographic isolation of methionine-containing peptides for gel-free proteome analysis: identification of more than 800 Escherichia coli proteins

Kris GevaertJozef Van DammeMarc GoethalsGrégoire ThomasBart HoorelbekeHans DemolLennart MartensMagda PuypeAn StaesJoël Vandekerckhove

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS