Research Explorer

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Researcher

An De Weer

14 Results

2011

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells

An De WeerJoni Van der MeulenPieter RondouTom TaghonTorsten A KonradKatleen De PreterPieter MestdaghTom Van MaerkenNadine Van RoyMarta JeisonIsaac YanivBarbara CauwelierLucien NoensHélène-Antoine PoirelPeter VandenbergheFrédéric LambertAnne De PaepeMaria García SánchezMaria OderoBruno VerhasseltJan PhilippéJo VandesompeleRotraud WieserNicole DastuguePieter Van VlierbergheBruce PoppeFranki Speleman

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Refinement of 1p36 alterations not involving PRDM16 in myeloid and lymphoid malignancies

François P DuhouxGeneviève AmeyeVirginie LambotChristian HerensFrédéric LambertSophie RaynaudIwona WlodarskaLucienne MichauxCatherine Roche-LestienneElise LabisSylvie TaviauxElise ChapiroFlorence Nguyen-KhacStéphanie StruskiSophie DobbelsteinNicole DastugueEric LippertFranki SpelemanNadine Van RoyAn De WeerKatrina RackPascaline TalmantSteven RichebourgFrancine MugneretIsabelle TigaudMarie-Joëlle MozziconacciSophy LaibeNathalie NadalChristine TerréJeanne-Marie LiboutonAnabelle DecottigniesMiikka VikkulaHélène A Poirel

A1 Journal Article in PLOS ONE

2010

Identification of two critically deleted regions within chromosome segment 7q35-q36 in EVI1 deregulated myeloid leukemia cell lines

An De WeerBruce PoppeSarah VergultPieter Van VlierbergheMarjan PetrickRobrecht De BockYves BenoitLucien NoensAnne De PaepeNadine Van RoyBjörn MentenFranki Speleman

A1 Journal Article in PLOS ONE

2009

A novel and universal method for microRNA RT-qPCR data normalization

Pieter MestdaghPieter Van VlierbergheAn De WeerDaniel MuthFrank WestermannFranki SpelemanJo Vandesompele

A1 Journal Article in GENOME BIOLOGY

Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs

Pieter Van VlierbergheAn De WeerPieter MestdaghTom FeysKatleen De PreterAnne De PaepeKathleen LambeinJo VandesompeleNadine Van RoyBruno VerhasseltBruce PoppeFranki Speleman

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Downregulation of miR-449a is essential for the survival of EVI1 positive leukemic cells through modulation of NOTCH1 and BCL2

An De WeerPieter MestdaghKatleen De PreterJoni Van der MeulenPieter Van VlierbergheTom Van MaerkenNadine Van RoyMarta JeisonIsaac YanivBarbara CauwelierLucien NoensHélène-Antoine PoirelPeter VandenbergheFrédéric LambertAnne De PaepeTorsten KonradRotraud WieserMaria Garcia SanchezMaria OderoBruno VerhasseltJan PhilippéJo VandesompeleNicole DastugueBruce PoppeFranki Speleman

MODULATION OF MIR-449A EXPRESSION DECREASES CELL VIABILITY, INCREASES APOPTOSIS AND INDUCES DIFFERENTIATION IN EVI1 DEREGULATED LEUKEMIA CELLS

An De WeerBruce PoppePieter MestdaghKatleen De PreterPieter Van VlierbergheNadine Van RoyM JeisonB CauwelierBruno VerhasseltJan PhilippéLucien NoensHA PoirelPieter VandenbergheF LambertAnne De PaepeN DastugueJo VandesompeleFranki Speleman

2008

EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22

An De WeerFranki SpelemanBarbara CauwelierNadine Van RoyNurten YigitBruno VerhasseltBarbara De MoerlooseYves BenoitLucien NoensDominik SelleslagEric LippertStephanie StruskiChristian BastardAnne De PaepePeter VandenbergheAnne HagemeijerNicole DastugueBruce Poppe

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

EVII activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22)

An De WeerBruce PoppeBarbara CauwelierA CARLIERJ DIERICKBruno VerhasseltJan PhilippéNadine Van RoyFranki Speleman

A1 Journal Article in BMC CANCER

MICRORNA PROFILING OF EVI1 DEREGULATED MYELOID LEUKEMIA

An De WeerBruce PoppePieter MestdaghPieter Van VlierbergheNadine Van RoyAnne De PaepeBruno VerhasseltJo VandesompeleFranki Speleman

2007

Identification of EVI1 transcriptional target genes using RNAI

An De WeerBruce PoppeB CAUWEUERNadine Van RoyBruno VerhasseltFranki Speleman

MicroRNA profiling of EVI1 deregulated myeloid leukemia

An De WeerBruce PoppePieter MestdaghNadine Van RoyAnne De PaepeBruno VerhasseltJo VandesompeleFranki Speleman

2006

Recurrent T(3;17)translocations in AML with EVI1 rearrangement

An De WeerBruce PoppeBarbara CauwelierNadine Van RoyN DASTUGUEBarbara De MoerlooseYves BenoitLucien NoensAnne De PaepeFranki Speleman

Screening for EVII: ectopic expression absent in T-cell acute lymphoblastic leukemia patients and cell lines

An De WeerBruce PoppeBarbara CauwelierNadine Van RoyN DASTUGUEA HAGEMEIJERAnne De PaepeFranki Speleman

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS