Research Explorer

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Researcher

Aliasghar Farhoudi Moghadam

Awards & Distinctions

25 Results

2021

A role for B cells to transmit hepatitis C virus infection

Isabelle DesombereFreya Van HoutteAliasghar Farhoudi MoghadamLieven VerhoyeCaroline BuysschaertYvonne GijbelsSibyl CouventW SwinnenHans Van VlierbergheAndré Elewaut et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2018

Development and characterization of a human monoclonal antibody targeting the N-terminal region of hepatitis C virus envelope glycoprotein E1

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeJonathan BallJean DubuissonSteven KH FoungArvind H PatelMats AA Persson et al.

A1 Journal Article in VIROLOGY

2017

A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo

Isabelle DesombereAhmed Atef Ahmed Abouzeid MesalamRichard A UrbanowiczFreya Van HoutteLieven VerhoyeZhen-Yong KeckAliasghar Farhoudi MoghadamKoen VercauterenKarin WeeningThomas F Baumert et al.

A1 Journal Article in ANTIVIRAL RESEARCH

Characterization of a novel monoclonal antibody targeting epitope II within hepatitis C virus E2 envelope glycoprotein

Philip MeulemanAhmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczFreya Van HoutteLieven VerhoyeZhen-Yong KeckAliasghar Farhoudi MoghadamKoen VercauterenKarin Weening et al.

Development and characterization of a human monoclonal antibody for prevention of HCV recurrence in liver transplant patients

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonKoen VercauterenAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeMats PerssonJonathan Ball et al.

Effect of hepatitis E virus infection on the human hepatic innate immune response in human liver chimeric mice

Ibrahim Mahmoud Sayed IbrahimLieven VerhoyeLaurance CocquerelFlorence AbravanelLander FoquetClaire MontpellierYannick DebingAliasghar Farhoudi MoghadamCzeslaw WychowskiJean Dubuisson et al.

Impact of HEV infection on the human hepatic innate immune response in human liver chimeric mice

Ibrahim Mahmoud Sayed IbrahimLieven VerhoyeLander FoquetFlorence AbravanelAliasghar Farhoudi MoghadamGeert Leroux-RoelsJacques IzopetPhilip Meuleman

Study of hepatitis E virus infection of genotype 1 and 3 in mice with humanised liver

Ibrahim Mahmoud Sayed IbrahimLieven VerhoyeLaurence CocquerelFlorence AbravanelLander FoquetClaire MontpellierYannick DebingAliasghar Farhoudi MoghadamCzeslaw WychowskiJean Dubuisson et al.

A1 Journal Article in GUT

Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy

Tanvi KheraDaniel TodtKoen VercauterenC Patrick McClureLieven VerhoyeAliasghar Farhoudi MoghadamSabin BhujuRobert GeffersThomas F BaumertEike Steinmann et al.

A1 Journal Article in ANTIVIRAL RESEARCH

Transmission of hepatitis E virus infection to human-liver chimeric FRG mice using patient plasma

Ibrahim Mahmoud Sayed IbrahimLander FoquetLieven VerhoyeAliasghar Farhoudi MoghadamFloresence AbravanelGeert Leroux-RoelsJacques IzopetPhilip Meuleman

A1 Journal Article in ANTIVIRAL RESEARCH

2016

Characterization of a novel human monoclonal antibody targeting the hepatitis C virus envelope protein

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonKoen VercauterenAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeMats PerssonJonathan Ball et al.

Effect of hepatitis E virus infection on the human hepatic innate immune response in human liver chimeric mice

Ibrahim Mahmoud Sayed IbrahimLieven VerhoyeLaurance CocquerelFlorence AbravanelLander FoquetClaire MontpellierYannick DebingAliasghar Farhoudi MoghadamCzeslaw WychowskiJean Dubuisson et al.

HVR1-mediated antibody evasion of highly infectious in vivo adapted HCV in humanised mice

Jannick PrentoeLieven VerhoyeRodrigo Velázquez MoctezumaCaroline BuysschaertAliasghar Farhoudi MoghadamRichard WangHarvey AlterPhilip MeulemanJens Bukh

A1 Journal Article in GUT

Monoclonal anti-envelope antibody AP33 protects humanized mice against a patient-derived hepatitis C virus challenge

Isabelle DesombereSamira Fafi-KremerFreya Van HouttePatrick PessauxAliasghar Farhoudi MoghadamLaura HeydmannLieven VerhoyeSarah ColeJane A McKeatingGeert Leroux-Roels et al.

A1 Journal Article in HEPATOLOGY

Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice

Koen VercauterenRichard JP BrownAhmed Atef Ahmed Abouzeid MesalamJuliane DoerrbeckerSabin BhujuRobert GeffersNaomi Van den EedeC Patrick McClureFulvia TroiseLieven Verhoye et al.

A1 Journal Article in GUT

2015

A broadly neutralizing monoclonal antibody targeting hepatitis C virus prevents viral infection in vitro and in uPA/SCID mice with humanized liver

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeMats PerssonJonathan BallGeert Leroux-Roels et al.

A broadly neutralizing monoclonal antibody targeting hepatitis C virus prevents viral infection in vitro and in uPA/SCID mice with humanized liver

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonKoen VercauterenAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeKarin WeeningMats Persson et al.

A broadly neutralizing monoclonal antibody targeting hepatitis C virus prevents viral infection in vitro and in uPA/SCID mice with humanized liver

Ahmed Atef Ahmed Abouzeid MesalamIsabelle DesombereRichard UrbanowiczDaniel X JohanssonAliasghar Farhoudi MoghadamFreya Van HoutteLieven VerhoyeMats PerssonJonathan BallGeert Leroux-Roels et al.

Human liver chimeric mice as a novel model for the study of hepatitis E virus infections

Ibrahim Mahmoud Sayed IbrahimLieven VerhoyeAliasghar Farhoudi MoghadamYannick DebingJohan NeytsGeert Leroux-RoelsRobert PurcellSuzanne EmersonPhilip Meuleman

Human liver chimeric mice as a novel model for the study of hepatitis E virus infections

Ibrahim Mahmoud Sayed IbrahimLieven VerhoyeLaurence CocquerelFlorence AbbravanelLander FoquetYannick DebingAliasghar Farhoudi MoghadamCzeslaw WychowskiJean DubuissonGeert Leroux-Roels et al.

Human liver chimeric mice as a novel model for the study of hepatitis E virus infections

Ibrahim Mahmoud Sayed IbrahimLieven VerhoyeY DebingF AbbravanelAliasghar Farhoudi MoghadamGeert Leroux-RoelsJ NeytsJ IzopetR PurcellS Emerson et al.

2014

Human liver chimeric mice as a novel model for the study of hepatitis E virus infections

Ibrahim Mahmoud Sayed IbrahimLieven VerhoyeAliasghar Farhoudi MoghadamYannick DebingJohan NeytsGeert Leroux-RoelsRobert PurcellSuzanne EmersonPhilip Meuleman

2012

A human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo

Philip MeulemanMaria Teresa CataneseLieven VerhoyeIsabelle DesombereAliasghar Farhoudi MoghadamChristopher T JonesTimothy SheahanKatarzyna GrzybRiccardo CorteseCharles M Rice et al.

A1 Journal Article in HEPATOLOGY

2011

In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus

Philip MeulemanJens BukhLieven VerhoyeAliasghar Farhoudi MoghadamThomas VanwolleghemRichard Y WangIsabelle DesombereHarvey AlterRobert H PurcellGeert Leroux-Roels

A1 Journal Article in HEPATOLOGY

2010

Production, characterization and in vitro testing of HBcAg-specific VHH intrabodies

Benedikte SerruysFreya Van HoutteAliasghar Farhoudi MoghadamGeert Leroux-RoelsPeter Vanlandschoot

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY