Research Explorer

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Researcher

Alexander Ryckaert

Awards & Distinctions

11 Results

2025

Comparative analysis of tablet dissolution behavior: Batch vs. Continuous direct compression

Kensaku MatsunamiAlexander RyckaertHanne VerrecasAna Filipa Tavares da SilvaAndrew AndersonHåkan WikströmMelanie DumareyJames MannThomas De BeerValérie Vanhoorne et al.

U Journal Article in International Journal of Pharmaceutics

Mathematical models of dissolution testing : challenges and opportunities toward real-time release testing

Kensaku MatsunamiAlexander RyckaertValérie VanhoorneAshish Kumar

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

2024

Hybrid modeling of T-shaped partial least squares regression and transfer learning for formulation and manufacturing process development of new drug products

Keita YaginumaKensaku MatsunamiLaure DescampsAlexander RyckaertThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

2021

Analysis of the effects of process parameters on start-up operation in continuous wet granulation

Kensaku MatsunamiAlexander RyckaertMichiel PeetersSara BadrHirokazu SugiyamaIngmar NopensThomas De Beer

A1 Journal Article in PROCESSES

Evaluation of torque as an in-process control for granule size during twin-screw wet granulation

Alexander RyckaertFanny StaufferA. FunkeD. DjuricValérie VanhoorneChris VervaetThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

TPLS as predictive platform for twin-screw wet granulation process and formulation development

Alexander RyckaertDaan Van HauwermeirenJens DhondtAlexander De ManAdrian FunkeDejan DjuricChris VervaetIngmar NopensThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

The influence of equipment design and process parameters on granule breakage in a semi-continuous fluid bed dryer after continuous twin-screw wet granulation

Alexander RyckaertMichael GhijsChristoph PortierDejan DjuricAdrian FunkeChris VervaetThomas De Beer

A1 Journal Article in PHARMACEUTICS

Towards an enhanced process understanding for a continuous pharmaceutical manufacturing process of tablets based on twin-screw wet granulation

Alexander RyckaertThomas De Beer

2020

In-line temperature measurement to improve the understanding of the wetting phase in twin-screw wet granulation and its use in process development

Fanny StaufferAlexander RyckaertValérie VanhoorneDaan Van HauwermeirenAdrian FunkeDejan DjuricChris VervaetIngmar NopensThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

2019

A multivariate approach to predict the volumetric and gravimetric feeding behavior of a low feed rate feeder based on raw material properties

Nils BostijnJens DhondtAlexander RyckaertEdina SzabóW DhondtBernd Van SnickValérie VanhoorneChris VervaetThomas De Beer

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Heat transfer evaluation during twin-screw wet granulation in view of detailed process understanding

Fanny StaufferAlexander RyckaertDaan Van HauwermeirenAdrian FunkeDejan DjuricIngmar NopensThomas De Beer

A1 Journal Article in AAPS PHARMSCITECH