Research Explorer

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Researcher

Alexander Lamoot

Awards & Distinctions

8 Results

2024

Combinatorial screening of biscarbamate ionizable lipids identifies a low reactogenicity lipid for lipid nanoparticle mRNA delivery

Emily De LombaerdeYong ChenTingting YeJulie DeckersGiulia MencarelliKim DeswarteHeleen LauwersRuben De CoenSabah KasmiSanne Bevers et al.

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

Lipid nanoparticle composition for adjuvant formulation modulates disease after influenza virus infection in quadrivalent influenza vaccine vaccinated mice

Sonia JangraAlexander LamootGagandeep SinghGabriel LaghlaliYong ChenTingting YeAdolfo García-SastreBruno De GeestMichael Schotsaert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2023

LXR signaling controls homeostatic dendritic cell maturation

Victor BosteelsSandra MaréchalClint De NolfSofie RennenJonathan MaelfaitSimon TavernierJessica VettersEvelien Van De VeldeFarzaneh FayazpourKim Deswarte et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

Lipid nanoparticle encapsulation empowers poly(I:C) to activate cytoplasmic RLRs and thereby increases its adjuvanticity

Alexander LamootSonia JangraGabriel LaghlaliPrajakta WarangLauren A. ChangSeok‐Chan ParkGagandeep SinghKim DeswarteZifu ZhongBenoit Louage et al.

A1 Journal Article in SMALL

Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids

Alexander LamootJoris LammensEmily De LombaerdeZifu ZhongMark GontsarikYong ChenThomas De BeerBruno De Geest

A1 Journal Article in BIOMATERIALS SCIENCE

2022

Lipid nanoparticle formulation of the TLR3 agonist polyI:C as a vaccine adjuvant

Alexander LamootBruno De Geest

2021

Covalent cell surface conjugation of nanoparticles by a combination of metabolic labeling and click chemistry

Alexander LamootAnnemiek UvynSabah KasmiBruno De Geest

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lipid-polyglutamate nanoparticle vaccine platform

Dorien Van LysebettenAlessio MalfantiKim DeswarteKaloian KoynovBianka GolbaTingting YeZifu ZhongSabah KasmiAlexander LamootYong Chen et al.

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES