Research Explorer

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Researcher

Alexander Koch

Awards & Distinctions

12 Results

2021

Downregulation of the FTO m(6)A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors

Jana JeschkeEvelyne CollignonClemence Al WardiMohammad KrayemMartin BizetYan JiaSoizic GaraudZena WimanaEmilie CalonneBouchra Hassabi et al.

A1 Journal Article in NATURE CANCER

2020

Asynchronous carbon sink saturation in African and Amazonian tropical forests

Wannes HubauSimon L. LewisOliver L. PhillipsKofi Affum-BaffoeHans BeeckmanAida Cuní-SanchezArmandu K. DanielsCorneille E. N. EwangoSophie FausetJacques M. Mukinzi et al.

A1 Journal Article in NATURE

2017

Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD) : a prospective multicentre randomised controlled trial (HOPE ECD-DBD)

Zoltan CziganyWenzel SchoeningTom Florian UlmerJan BednarschIakovos AmygdalosThorsten CramerXavier RogiersIrinel PopescuFlorin BoteaJiri Fronek et al.

A1 Journal Article in BMJ OPEN

2016

Molecular and epigenetic features of melanomas and tumor immune microenvironment linked to durable remission to ipilimumab-based immunotherapy in metastatic patients

Teofila SeremetAlexander KochYanina JansenMax SchreuerSofie WilgenhofVéronique Del MarmolDanielle LiènardKris ThielemansKelly SchatsMark Kockx et al.

A1 Journal Article in JOURNAL OF TRANSLATIONAL MEDICINE

2015

Different approaches to measuring gene expression and DNA methylation and their application in cancer research

Alexander KochWim Van CriekingeTim De MeyerGerben Menschaert

MEXPRESS : visualizing expression, DNA methylation and clinical TCGA data

Alexander KochTim De MeyerJana JeschkeWim Van Criekinge

A1 Journal Article in BMC GENOMICS

PROTEOFORMER : deep proteome coverage through ribosome profiling and MS integration

Jeroen CrappéElvis NdahAlexander KochSandra SteyaertDaria FijalkowskaSarah De KeulenaerEllen De MeesterTim De MeyerWim Van CriekingePetra Van Damme et al.

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2014

A proteogenomics approach integrating proteomics and ribosome profiling increases the efficiency of protein identification and enables the discovery of alternative translation start sites

Alexander KochDaria FijalkowskaSandra SteyaertElvis NdahJeroen CrappéSarah De KeulenaerEllen De MeesterMing MaBen ShenKris Gevaert et al.

A1 Journal Article in PROTEOMICS

2013

Alterations of immune response of non-small lung cancer with azacytidine

John WrangleWei WangAlexander KochHariharan EaswaranHelai P MohammadFrank VendettiWim Van CriekingeTim De MeyerZhengzong DuPrincy Parsana et al.

A1 Journal Article in ONCOTARGET

Deep proteome coverage based on ribosome profiling aids mass spectrometry-based protein and peptide discovery and provides evidence of alternative translation products and near-cognate translation initiation events

Gerben MenschaertWim Van CriekingeTineke NotelaersAlexander KochJeroen CrappéKris GevaertPetra Van Damme

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Mass spectrometry and ribosome profiling, a perfect combination towards a more comprehensive identification strategy of true in vivo protein forms

Jeroen CrappéAlexander KochSandra SteyaertWim Van CriekingePetra Van DammeGerben Menschaert

2012

Biomarkers for detection and prognosis of breast cancer identified by a functional hypermethylome screen

Jana JeschkeLeander Van NesteSabine C GlöcknerMashaal DhirMarilia Freitas CalmonValerie DeregowskiWim Van CriekingeIlse VlassenbroeckAlexander KochTimothy A Chan et al.

A1 Journal Article in EPIGENETICS