Research Explorer

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Researcher

Alessio Lissoni

Awards & Distinctions

25 Results

2023

Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments

Luc LeybaertMaarten De SmetAlessio LissoniRosalie AllewaertH. Llewelyn RoderickGeert BultynckMario DelmarKarin R. SipidoKatja Witschas

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

Cx43 hemichannel and Panx1 channel modulation by Gap19 and 10Panx1 peptides

Alessio LissoniSiyu TaoRosalie AllewaertKatja WitschasLuc Leybaert

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2022

Novel modulators of connexin 43 hemichannel in the heart : from peptides to pathways

Alessio LissoniLuc LeybaertAlexander Panfilov

2021

Connexin 43 phosphorylation by casein kinase 1 is essential for the cardioprotection by ischemic preconditioning

Christine HirschhäuserAlessio LissoniPhilipp Maximilian GörgePaul D. LampeJacqueline HegerKlaus-Dieter SchlüterLuc LeybaertRainer SchulzKerstin Boengler

A1 Journal Article in BASIC RESEARCH IN CARDIOLOGY

Cx43 hemichannel microdomain signaling at the intercalated disc enhances cardiac excitability

Maarten De SmetAlessio LissoniTimur NezlobinskiiNan WangEef DriesMarta Pérez-HernándezXianming LinMatthew AmoniTim VervlietKatja Witschas et al.

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes

Alessio LissoniPaco HulpiauTânia Martins-MarquesNan WangGeert BultynckRainer SchulzKatja WitschasHenrique GiraoMaarten De SmetLuc Leybaert

A1 Journal Article in CARDIOVASCULAR RESEARCH

2020

Gap19, a Cx43 hemichannel inhibitor, acts as a gating modifier that decreases main state opening while increasing substate gating

Alessio LissoniNan WangTimur NezlobinskiiMaarten De SmetAlexander PanfilovNele VandersickelLuc LeybaertKatja Witschas

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2018

Activation of Cx43 hemichannels by TNFα in HeLa cells stably overexpressing Cx43 and in the endothelial cell line EA.hy926

Stijn VerwaerdeMaarten De SmetTinneke DelvaeyeAlessio LissoniPeter VandenabeeleLuc Leybaert

Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+

Alessio LissoniMaarten De SmetPaco HulpiauTania Martins-MarquesNan WangHenrique GiraoLuc Leybaert

RyR2 regulates Cx43 hemichannel [Ca2+]i-dependent activation in cardiomyocytes

Alessio LissoniMaarten De SmetTania Martins-MarquesNan WangHenrique GiraoPaco HulpiauLuc Leybaert

RyR2 regulates Cx43 hemichannel [Ca2+]i-dependent activation in cardiomyocytes

Alessio LissoniMaarten De SmetTania Martins-MarquesNan WangHenrique GiraoPaco HulpiauLuc Leybaert

RyR2 regulates Cx43 hemichannel [Ca2+]i-dependent activation in cardiomyocytes

Alessio LissoniMaarten De SmetTania Martins-MarquesHerique GiraoNan WangPaco HulpiauLuc Leybaert

2017

Activation, regulation and arrhythmogenic implications of Cx43 hemichannels in ventricular cardiomyocytes

Maarten De SmetAlessio LissoniNan WangEef DriesKarin SipidoLuc Leybaert

Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+

Alessio LissoniMaarten De SmetTânia Martins-MarquesNan WangHenrique GirãoLuc Leybaert

Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+, and is modulated by CaMKII and p38MAPK

Alessio LissoniMaarten De SmetNan WangLuc Leybaert

Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+, and is modulated by CaMKII and p38MAPK

Alessio LissoniMaarten De SmetNan WangLuc Leybaert

Mitochondrial Cx43 hemichannels contribute to mitochondrial calcium entry and cell death in the heart

Ashish Kumar GadicherlaNan WangMarco BulicEsperanza Agullo-PascualAlessio LissoniMaarten De SmetMario DelmarGeert BultynckDmitri KryskoAmadou Camara et al.

A1 Journal Article in BASIC RESEARCH IN CARDIOLOGY

Modulation of Cx43 hemichannels by TNFα in HeLa cells overexpressing Cx43

Stijn VerwaerdeMaarten De SmetTinneke DelvaeyeAlessio LissoniPeter VandenabeeleDmitri KryskoLuc Leybaert

Role of Cx43 hemichannels in ventricular arrhythmia associated with abnormal Ca2+ homeostasis

Maarten De SmetAlessio LissoniNan WangLuc Leybaert

The expression of the rare caveolin-3 variant T78M alters cardiac ion channels function and membrane excitability

Giulia CampostriniMattia BonzanniAlessio LissoniClaudia BazziniRaffaella MilanesiElena VezzoliMaura FrancoliniMirko BaruscottiAnnalisa BucchiIlaria Rivolta et al.

A1 Journal Article in CARDIOVASCULAR RESEARCH

2016

Activation, regulation and arrhythmogenic implications of Cx43 hemichannels in ventricular cardiomyocytes

Maarten De SmetAlessio LissoniNan WangLuc Leybaert

Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+, and is modulated by CaMKII

Alessio LissoniMaarten De SmetNan WangLuc Leybaert

Cx43 hemichannels in ventricular cardiomyocytes can be activated by an elevation of cytoplasmic Ca2+ through a CaM-dependent signaling cascade and are a potent contributor to cardiac arrhythmogenesis

Maarten De SmetAlessio LissoniNan WangLuc Leybaert

Cx43 hemichannels in ventricular cardiomyocytes can be activated by an elevation of cytoplasmic Ca2+ through a CaM-dependent signaling cascade and are a potent contributor to cardiac arrhythmogenesis

Maarten De SmetAlessio LissoniNan WangLuc Leybaert

Whole-cell patch clamp recordings of unitary connexin 43 hemichannel currents

Nan WangAlessio LissoniMaarten De SmetKarin R SipidoLuc Leybaert

Bookchapter in Gap junction channels and hemichannels