Research Explorer

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Researcher

Agnieszka Łątka

Publications & Research Data

Awards & Distinctions

39 Results

2025

A VersaTile approach to reprogram the specificity of the R2-type tailocin towards different serotypes of Escherichia coli and Klebsiella pneumoniae

Dorien DamsCélia PasAgnieszka ŁątkaZuzanna Drulis-KawaLars FieselerYves Briers

A1 Journal Article in ANTIBIOTICS-BASEL

RBP grafting and rebooting of engineered Klebsiella phages with an altered host range

Dorien DamsAgnieszka ŁątkaMathilde HulsensZuzanna Drulis-KawaYves Briers

RBP grafting and rebooting of engineered Klebsiella phages with an altered host range

Dorien DamsAgnieszka ŁątkaMathilde HulsensZuzanna Drulis-KawaYves Briers

2024

A VersaTile approach to reprogram and broaden the specificity of R2 tailocins towards E. coli and K. pneumoniae

Dorien DamsCélia PasAgnieszka ŁątkaZuzanna Drulis-Kawalars FieselerYves Briers

Development of a standardized plug-and-play strategy for receptor-binding protein engineering of Klebsiella pneumoniae phages

Dorien DamsAgnieszka ŁątkaMathilde HulsensZuzanna Drulis-KawaYves Briers

KlebPhaCol : a community-driven resource for Klebsiella research identified a novel gut phage order associated with the human gut

Daniela Rothschild-RodriguezKai S. LambonAgnieszka ŁątkaAna Rita CostaAnna MantzouratouClaire KingDimitri BoeckaertsElizabeth SheridanFrancesca MerrickFrancis Drobniewski et al.

Machine learning tools versus manual approach for detection of Klebsiella phage depolymerases

Ilaria De AngelisAgnieszka ŁątkaDimitri BoeckaertsBritt Van MieghemYves Briers

Meeting report of the second symposium of the Belgian Society for Viruses of Microbes and launch of the Phage Valley

Salome DesmechtAgnieszka ŁątkaPieter-Jan CeyssensAbel Garcia-PinoAnnika GillisRob LavigneGipsi Lima-MendezJelle MatthijnssensRoberto VázquezJolien Venneman et al.

A1 Journal Article in VIRUSES-BASEL

Organization of the hyperbranched receptor-binding protein system in Klebsiella jumbo phages φKp24 and FKAN

Mathilde HulsensMaria PozniakSara JablonskaAgnieszka ŁątkaZuzanna Drulis-KawaYves Briers

2023

Biology-based machine learning to predict phage-host specificity for the clinical phage therapist

Dimitri BoeckaertsCélia PasAgnieszka ŁątkaMichiel StockCelia Ferriol-GonzálezRafael SanjuanPilar Domingo-CalapLars FieselerBernard De BaetsYves Briers

Foundation of the Belgian Society for Viruses of Microbes and meeting report of its inaugural symposium

Agnieszka ŁątkaAbram AertsenDimitri BoeckaertsBob BlasdelPieter-Jan CeyssensAbel Garcia-PinoAnnika GillisRob LavigneGipsi Lima-MendezJelle Matthijnssens et al.

A1 Journal Article in VIRUSES-BASEL

Klebsiella phage KP34gp57 capsular depolymerase structure and function: from a serendipitous finding to the design of active mini-enzymes against K. pneumoniae

Barbara MaciejewskaFlavia SquegliaAgnieszka ŁątkaMario PriviteraSebastian OlejniczakPaulina SwitalaAlessia RuggieroDaniela MarascoEliza KramarskaZuzanna Drulis-Kawa et al.

A1 Journal Article in MBIO

Phage tailspike modularity and horizontal gene transfer reveals specificity towards E. coli O-antigen serogroups

Célia PasAgnieszka ŁątkaLars FieselerYves Briers

A1 Journal Article in VIROLOGY JOURNAL

Understanding the RBP modules function of KP32 as a podophage model

Agnieszka ŁątkaDorien DamsFlavia SqueqliaLennert ScholiersAleksandra OtwinowskaSebastian OlejniczakBarbara MaciejewskaDiana Gutierrez FernandezRita BerisioZuzanna Drulis-Kawa et al.

Understanding the RBP modules function of KP32 as a podophage model

Agnieszka ŁątkaDorien DamsFlavia SqueqliaLennert ScholiersAleksandra OtwinowskaSebastian OlejniczakBarbara MaciejewskaDiana Gutierrez FernandezRita BerisioZuzanna Drulis-Kawa et al.

2022

A blueprint of tail fiber modularity and its relationship with host specificity for STEC serovars

Célia PasAgnieszka ŁątkaLars FieselerYves Briers

Development of a synthetic, VersaTile strategy for receptor-binding protein engineering of Klebsiella pneumoniae phages

Dorien DamsAgnieszka ŁątkaMathilde HulsensZuzanna Drulis-KawaYves Briers

Development of a synthetic, VersaTile strategy for receptor-binding protein engineering of Klebsiella pneumoniae phages

Dorien DamsAgnieszka ŁątkaMathilde HulsensZuzanna Drulis-KawaYves Briers

High-resolution reconstruction of a Jumbo-bacteriophage infecting capsulated bacteria using hyperbranched tail fibers

Ruochen OuyangAna Rita CostaC. Keith CassidyAleksandra OtwinowskaVera C. J. WilliamsAgnieszka ŁątkaPhill J. StansfeldZuzanna Drulis-KawaYves BriersDaniel M. Pelt et al.

A1 Journal Article in NATURE COMMUNICATIONS

Insight into key structural points of capsule-targeting phage depolymerases specific to Klebsiella pneumoniae K63

Aleksandra OtwinowskaSebastian OlejniczakBarbara MaciejewskaAgnieszka ŁątkaFlavia SquegliaYves BriersTomasz KościółekRafał MostowyRita BerisioZuzanna Drulis-Kawa

Launch of the Belgian Society for Viruses of Microbes

Abram AerstenBob BlasdelDimitri BoeckaertsPieter-Jan CeyssensAbel Garcia-PinoAnnika GillisAgnieszka ŁątkaRob LavigneGipsi Lima-MendezJelle Matthijnssens et al.

Optimization of propidium monoazide qPCR (viability-qPCR) to quantify the killing by the Gardnerella-specific endolysin PM-477, directly in vaginal samples from women with bacterial vaginosis

Agnieszka ŁątkaLeen Van SimaeyMarijke ReyndersPiet CoolsTess RogierBarbara LebbeLorenzo CorsiniChristine LandlingerMario Vaneechoutte

A1 Journal Article in ANTIBIOTICS-BASEL

Synthetic phage tail-like bacteriocins targeting Shiga toxin-producing Escherichia coli

Célia PasDorien DamsAgnieszka ŁątkaLars FieselerYves Briers

The organization and evolution of receptor-binding proteins in Klebsiella phages by exploiting novel tools in synthetic biology

Agnieszka ŁątkaDorien DamsFlavia SqueqliaLennert ScholiersMathilde HulsensAleksandra OtwinowskaSebastian OlejniczakBarbara MaciejewskaRita BerisioZuzanna Drulis-Kawa et al.

The specific capsule depolymerase of phage PMK34 sensitizes Acinetobacter baumannii to serum killing

Karim Abdelkader Soufi AbdelkaderDiana Gutierrez FernandezAgnieszka ŁątkaDimitri BoeckaertsZuzanna Drulis-KawaBjorn CrielHans GerstmansAmal SafaanAhmed S. KhairallaYasser Gaber et al.

A1 Journal Article in ANTIBIOTICS-BASEL

Unravelling the function of carbohydrate binding domains in a highly specific tailspike of Klebsiella phage KP32

Agnieszka ŁątkaFlavia SqueqliaDorien DamsLennert ScholiersAleksandra OtwinowskaSebastian OlejniczakDiana Gutierrez FernandezBarbara MaciejewskaRita BerisioZuzanna Drulis-Kawa et al.

Unravelling the function of the carbohydrate binding domains in a highly specific tailspike of Klebsiella phage KP32

Agnieszka ŁątkaFlavia SqueqliaDorien DamsLennert ScholiersAleksandra OtwinowskaSebastian OlejniczakDiana Gutierrez FernandezBarbara MaciejewskaRita BerisioZuzanna Drulis-Kawa et al.

2021

Engineering the modular receptor-binding proteins of Klebsiella phages switches their capsule serotype specificity

Agnieszka ŁątkaSebastien LemireDennis GrimonDorien DamsBarbara MaciejewskaTimothy LuZuzanna Drulis-KawaYves Briers

A1 Journal Article in MBIO

2020

Structural and functional studies of a klebsiella phage capsule depolymerase tailspike : mechanistic insights into capsular degradation

Flavia SquegliaBarbara MaciejewskaAgnieszka ŁątkaAlessia RuggieroYves BriersZuzanna Drulis-KawaRita Berisio

A1 Journal Article in STRUCTURE

2019

Characterization and in vitro engineering of exopolysaccharide (EPS) depolymerases originated from Klebsiella phages

Agnieszka ŁątkaZuzanna Drulis-KawaYves Briers

Modeling the architecture of depolymerase-containing receptor binding proteins in Klebsiella phages

Agnieszka ŁątkaPetr G LeimanZuzanna Drulis-KawaYves Briers

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Modelling the architecture of depolymerase-containing receptor binding proteins in Klebsiella phages

Agnieszka ŁątkaPetr G LeimanZuzanna Drulis-KawaYves Briers

2018

Phage-borne depolymerases decrease Klebsiella pneumoniae resistance to innate defense mechanisms

Grazyna Majkowska-SkrobekAgnieszka ŁątkaRita BerisioFlavia SquegliaBarbara MaciejewskaYves BriersZuzanna Drulis-Kawa

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

2017

Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process

Agnieszka ŁątkaBarbara MaciejewskaGrazyna Majkowska-SkrobekYves BriersZuzanna Drulis-Kawa

A1 Journal Article in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Phage life cycles behind bacterial biodiversity

Tomasz OlszakAgnieszka ŁątkaBartosz RoszniowskiMiguel A ValvanoZuzanna Drulis-Kawa

A1 Journal Article in CURRENT MEDICINAL CHEMISTRY

The O-specific polysaccharide lyase from the phage LKA1 tailspike reduces Pseudomonas virulence

Tomasz OlszakMikhail M ShneiderAgnieszka ŁątkaBarbara MaciejewskaChristopher BrowningLada V SychevaAnneleen CornelissenKatarzyna Danis-WlodarczykSofya N SenchenkovaAlexander S Shashkov et al.

A1 Journal Article in SCIENTIFIC REPORTS

The temperate Burkholderia phage AP3 of the Peduovirinae shows efficient antimicrobial activity against B. cenocepacia of the IIIA lineage

Bartosz RoszniowskiAgnieszka ŁątkaBarbara MaciejewskaDieter VandenheuvelTomasz OlszakYves BriersGiles S HoltMiguel A ValvanoRob LavigneDarren L Smith et al.

A1 Journal Article in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

2016

Capsule-targeting depolymerase, derived from Klebsiella KP36 phage, as a tool for the development of anti-virulent strategy

Grażyna Majkowska-SkrobekAgnieszka ŁątkaRita BerisioBarbara MaciejewskaFlavia SquegliaMaria RomanoRob LavigneCarsten StruveZuzanna Drulis-Kawa

A1 Journal Article in VIRUSES-BASEL

2015

A suggested new bacteriophage genus, 'Kp34likevirus', within the Autographivirinae subfamily of Podoviridae

Harald ErikssonBarbara MaciejewskaAgnieszka ŁątkaGrazyna Majkowska-SkrobekMarios HellstrandÖjar MeleforsJin-Town WangAndrew KropinskiZuzanna Drulis-KawaAnders Nilsson

A1 Journal Article in VIRUSES-BASEL