Research Explorer

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Researcher

Adelbert De Clercq

Publications & Research Data

Awards & Distinctions

61 Results

2026

Decoding phenotypic variability in osteogenesis imperfecta : zebrafish as a model for molecular and (ultra)structural insights

Paul CouckAndy WillaertAdelbert De Clercq

2025

Scale ring formation and mineralization reflect events in the life of farmed Atlantic salmon

Adelbert De ClercqJOANA HUGUETLucia DrábikováPaul Eckhard Witten

2024

Early mechanisms of aortic failure in a zebrafish model for thoracic aortic dissection and rupture

Michiel VanhooydonckMaxim VerleeMarta Guerreiro Santana Ramos Da SilvaLore PottieAnnekatrien BoelMatthias Van ImpeHanna De SaffelLisa CaboorPiyanoot TapaneeyaphanAnne Bonnin et al.

Early mechanisms of aortic failure in a zebrafish model for thoracic aortic dissection and rupture

Michiel VanhooydonckMaxim VerleeMarta Guerreiro Santana Ramos Da SilvaLore PottieAnnekatrien BoelMatthias Van ImpeHanna De SaffelLisa CaboorPiyanoot TapaneeyaphanAnne Bonnin et al.

Socio-economic data dynamics of the fish processing sector over time, a Belgian case study.

Adelbert De ClercqMattias VermeerschWim AllegaertEls Torreele

2023

A tapt1 knock-out zebrafish line with aberrant lens development and impaired vision models human early-onset cataract

Tamara JaraysehBrecht GuillemynHanna De SaffelJan Willem BekDelfien SyxSofie SymoensYannick GansemansFilip Van NieuwerburghSujatha JagadeeshJayarekha Raja et al.

A1 Journal Article in HUMAN GENETICS

Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for Osteogenesis Imperfecta

Sophie DebaenstHanna De SaffelJan Willem BekAdelbert De ClercqTamara JaraysehLauren SahdPaul CouckeAndy Willaert

Elevated water CO2 can prevent dietary-induced osteomalacia in post-smolt Atlantic salmon (Salmo salar, L.)

Lucia DrábikováPer Gunnar FjelldalMuhammad Naveed YousafThea MorkenAdelbert De ClercqCharles McGurkPaul Eckhard Witten

A1 Journal Article in BIOMOLECULES

Identification of modifier genes underlying intra-familial phenotypic variability in zebrafish OI models using whole exome sequencing and linkage analysis

Tamara JaraysehAdelbert De ClercqToon RosseelMauro Alessio MilazzoAndy WillaertPaul Coucke

Syntaxin 18 defects in human and zebrafish unravel key roles in early cartilage and bone development

Brecht GuillemynHanna De SaffelJan Willem BekPiyanoot TapaneeyaphanAdelbert De ClercqTamara JaraysehSophie DebaenstAndy WillaertRiet De RyckePeter H. Byers et al.

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

Syntaxin-18 defects in human and zebrafish cause traffic jams and unravel key roles in early bone development

Brecht GuillemynHanna De SaffelJan Willem BekPiyanoot TapaneeyaphanAdelbert De ClercqTamara JaraysehSophie DebaenstAndy WillaertPeter ByersPaul Coucke et al.

The establishment of the first reported zebrafish model for thoracic aortic dissection and rupture

Michiel VanhooydonckMaxim VerleeLore PottieAnnekatrien BoelPiyanoot TapaneeyaphanMarta Guerreiro Santana Ramos Da SilvaAdelbert De ClercqLisa CaboorMatthias Van ImpeDelfien Syx et al.

The establishment of the first reported zebrafish model for thoracic aortic dissection and rupture

Michiel VanhooydonckMaxim VerleeLore PottieAnnekatrien BoelPiyanoot TapaneeyaphanMarta Guerreiro Santana Ramos Da SilvaAdelbert De ClercqLisa CaboorMatthias Van ImpeDelfien Syx et al.

The establishment of the first reported zebrafish model for thoracic aortic dissection and rupture

Michiel VanhooydonckLore PottieAnnekatrien BoelPiyanoot TapaneeyaphanMarta Guerreiro Santana Ramos Da SilvaAdelbert De ClercqMatthias Van ImpeDelfien SyxAndy WillaertLisa Caboor et al.

Unraveling of the ultrastructural features that determine the variability in phenotypic severity in different dominant forms of OI, using the zebrafish as a model

Lauren SahdCaitlin DebaeneSophie DebaenstTamara JaraysehHanna De SaffelMyriam ClaeysJan Willem BekCharlotte GistelinckFrans RodenburgPhil Salmon et al.

Zebrafish : a model for developmental biology

Adelbert De Clercq

2022

A tapt1 knockout zebrafish line with aberrant lens development and impaired vision models human pediatric cataract

Tamara JaraysehBrecht GuillemynHanna De SaffelJan Willem BekSujatha JagadeeshSofie SymoensFransiska MalfaitDelfien SyxFilip Van NieuwerburghYannick Gansemans et al.

A tapt1 knockout zebrafish line with aberrant lens development and impaired vision models human pediatric cataract

Tamara JaraysehBrecht GuillemynHanna De SaffelJan Willem BekSujatha JagadeeshSofie SymoensFransiska MalfaitDelfien SyxFilip Van NieuwerburghYannick Gansemans et al.

Alterations in glycosaminoglycan biosynthesis associated with the Ehlers-Danlos syndromes

Delfien SyxSarah DelbaereCatherine BuiAdelbert De ClercqGöran LarsonShuji MizumotoTomoki KoshoSylvie Fournel-GigleuxFransiska Malfait

A1 Journal Article in AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Bi-allelic loss-of-function variants in LTBP1cause autosomal recessive cutis laxa syndrome

Lore PottieChristin S. AdamoAude BeyensSteffen LuetkePiyanoot TapaneeyaphanAdelbert De ClercqPhil SalmonRiet De RyckeAlper GezdiriciElif Yilmaz Gulec et al.

Crispant screening in zebrafish as a promising approach for rapid functional screening of osteoporosis candidate genes and known genes for Osteogenesis Imperfecta

Sophie DebaenstHanna De SaffelJan Willem BekAdelbert De ClercqTamara JaraysehLauren SahdPaul CouckeAndy Willaert

The establishment of the first reported zebrafish model for thoracic aortic dissection and rupture

Michiel VanhooydonckLore PottieAnnekatrien BoelPiyanoot TapaneeyaphanMarta Guerreiro Santana Ramos Da SilvaAdelbert De ClercqLisa CaboorMatthias Van ImpeAndy WillaertPatrick Sips et al.

The establishment of the first reported zebrafish model for thoracic aortic dissection and rupture

Michiel VanhooydonckLore PottieAnnekatrien BoelPiyanoot TapaneeyaphanMarta Guerreiro Santana Ramos Da SilvaLisa CaboorAdelbert De ClercqMatthias Van ImpeAndy WillaertPatrick Sips et al.

What will happen to my smolt at harvest? Individually tagged Atlantic salmon help to understand possible progression and regression of vertebral deformities

Lucia DrábikováPer Gunnar FjelldalAdelbert De ClercqM. Naveed YousafThea MorkenCharles McGurkPaul Eckhard Witten

A1 Journal Article in AQUACULTURE

2021

An overview of investigational and experimental drug treatment strategies for Marfan syndrome

Violette DeleeuwAdelbert De ClercqJulie De BackerPatrick Sips

A2 Journal Article in JOURNAL OF EXPERIMENTAL PHARMACOLOGY

Bi-allelic premature truncating variants in LTBP1 cause cutis laxa syndrome

Lore PottieChristin S. AdamoAude BeyensSteffen LütkePiyanoot TapaneeyaphanAdelbert De ClercqPhil L. SalmonRiet De RyckeAlper GezdiriciElif Yilmaz Gulec et al.

A1 Journal Article in AMERICAN JOURNAL OF HUMAN GENETICS

Identification of modifier genes underlying intra-familial phenotypic variability in zebrafish OI models using whole exome sequencing (WES) and linkage analysis

Tamara JaraysehAdelbert De ClercqToon RosseelMauro Alessio MilazzoAndy WillaertPaul Coucke

Identification of skeletal deformities towards deep phenotyping of zebrafish (Danio rerio) connective tissue disease models

Caitlin DebaeneAdelbert De ClercqAndy WillaertPaul Coucke

Lrp5 mutant and crispant zebrafish faithfully model human osteoporosis, establishing the zebrafish as a platform for CRISPR‐based functional screening of osteoporosis candidate genes

Jan Willem BekChen ShochatAdelbert De ClercqHanna De SaffelAnnekatrien BoelJuriaan MetzFrans RodenburgDavid KarasikAndy WillaertPaul Coucke

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

Photoconvertible fluorescent proteins : a versatile tool in zebrafish skeletal imaging

Jan Willem BekAdelbert De ClercqHanna De SaffelMieke SoenensAnn HuysseunePaul Eckhard WittenPaul CouckeAndy Willaert

A1 Journal Article in JOURNAL OF FISH BIOLOGY

The ZE-Tunnel : an affordable, easy-to-assemble, and user-friendly benchtop zebrafish swim tunnel

Jan Willem BekAdelbert De ClercqPaul CouckeAndy Willaert

A1 Journal Article in ZEBRAFISH

Vertebral column adaptations in juvenile Atlantic salmon Salmo salar, L. as a response to dietary phosphorus

Lucia DrábikováPer Gunnar FjelldalAdelbert De ClercqM. Naveed YousafThea MorkenCharles McGurkPaul Eckhard Witten

A1 Journal Article in AQUACULTURE

2020

b3galt6 Knock-out zebrafish recapitulate β3GalT6-deficiency disorders in human and reveal a trisaccharide proteoglycan linkage region

Sarah DelbaereAdelbert De ClercqShuji MizumotoFredrik NobornJan Willem BekLien AlluynCharlotte GistelinckDelfien SyxPhil L. SalmonPaul Coucke et al.

A1 Journal Article in FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

b3galt6 knock-out zebrafish recapitulate β3GalT6-deficiency disorders in human and reveal a trisaccharide proteoglycan linkage region

Sarah DelbaereAdelbert De ClercqShuji MizumotoFredrik NobornJan Willem BekLien AlluynCharlotte GistelinckDelfien SyxPhil L. SalmonPaul Coucke et al.

Type I collagen differences in farmed Chinook salmon (Oncorhynchus tshawytscha) in New Zealand

Matthew R. PerrottBailey A. LovettAdelbert De ClercqPeter S. DavieJohn S. MundayPatrick C.H. MorelMark A. PreeceJane E. SymondsSeumas P. WalkerTrevor Loo et al.

A1 Journal Article in AQUACULTURE

Zebrafish : a resourceful vertebrate model to investigate skeletal disorders

Francesca TonelliJan Willem BekRoberta BesioAdelbert De ClercqLaura LeoniPhil SalmonPaul CouckeAndy WillaertAntonella Forlino

A1 Journal Article in FRONTIERS IN ENDOCRINOLOGY

2019

In-depth characterization of the ultrastructural variability of the vertebral column in a severe, medium and mildly affected Osteogenesis Imperfecta zebrafish model

Adelbert De ClercqHanna De SaffelJan Willem BekMyriam ClaeysPetra VermassenPaul CouckeAndy Willaert

The zebrafish as a model for fragile bone disorders

Jan Willem BekHanna De SaffelOsama EssawiAdelbert De ClercqPaul Eckhard WittenAnn HuysseuneJuriaan MetzPhil SalmonPaul CouckeAndy Willaert

The zebrafish as a model for recessive types of osteogenesis imperfecta

Jan Willem BekHanna De SaffelOsama EssawiAdelbert De ClercqPaul Eckhard WittenAnn HuysseunePhil SalmonPaul CouckeAndy Willaert

The zebrafish as a model for recessive types of Osteogenesis Imperfecta.

Jan Willem BekHanna De SaffelOsama EssawiAdelbert De ClercqPaul Eckhard WittenAnn HuysseunePhil SalmonPaul CouckeAndy Willaert

2018

Collagen type-1 differences in farmed Chinook salmon (Oncorhynchus tshawytscha) in New Zealand

Matthew R PerrottAdelbert De ClercqBailey A LovettPeter S DavieJohn S MundayMark A PreeceJane E SymondsSeumas P WalkerTrevor LooGillian Norris et al.

Supernumerary teeth in the pharyngeal dentition of slow-developing zebrafish (Danio rerio, Hamilton, 1822)

Iris WoltmannF ShkilAdelbert De ClercqAnn HuysseunePaul Eckhard Witten

A1 Journal Article in JOURNAL OF APPLIED ICHTHYOLOGY

Temperature sensitive regions of the Chinook salmon vertebral column : vestiges and meristic variation

Adelbert De ClercqMatthew R PerrottPeter S DavieMark A PreeceMatthew AG OwenAnn HuysseunePaul Eckhard Witten

A1 Journal Article in JOURNAL OF MORPHOLOGY

The external phenotype-skeleton link in post-hatch farmed Chinook salmon (Oncorhynchus tshawytscha)

Adelbert De ClercqMatthew R PerrottPeter S DavieMark A PreeceAnn HuysseuneEckhard Witten

The external phenotype-skeleton link in post-hatch farmed Chinook salmon (Oncorhynchus tshawytscha)

Adelbert De ClercqMR PerrottPS DavieMA PreeceAnn HuysseunePaul Eckhard Witten

A1 Journal Article in JOURNAL OF FISH DISEASES

Vertebral abnormalities in free-living Chinook salmon (Oncorhynchus tshawytscha, Walbaum) in New Zealand

Peter S. DavieSeumas P. WalkerMatthew R. PerrottJane E. SymondsMark PreeceAdelbert De ClercqJohn S. Munday

A1 Journal Article in NEW ZEALAND JOURNAL OF MARINE AND FRESHWATER RESEARCH

Vertebral column regionalisation in Chinook salmon, Oncorhynchus tshawytscha

Adelbert De ClercqMatthew R PerrottPeter S DavieMark A PreeceBen WybourneNicole RuffAnn HuysseuneEckhard Witten

2017

Linking external and internal skeletal malformations in early life stages of Chinook Salmon : diagnosis, pathologies and prevention Strategies

Adelbert De ClercqMatthew R. PerrottPeter S. DavieMark A. PreeceBen WybourneNicole RuffAnn HuysseunePaul Eckhard Witten

Linking external and internal skeletal malformations in early life stages of Chinook salmon : diagnosis, pathologies and recommendations

Adelbert De Clercq

Vertebral column regionalisation in Chinook salmon, Oncorhynchus tshawytscha

Adelbert De ClercqMR PerrottPS DavieMA PreeceB WybourneN RuffAnn HuysseunePaul Eckhard Witten

A1 Journal Article in JOURNAL OF ANATOMY

2016

A refined system of vertebral column subdivision in Chinook salmon, Oncorhynchus tshawytscha (Actinopterygii : Salmonidae)

Adelbert De ClercqMatthew R PerrottPeter S. DavieMark A. PreeceBen WybourneNicole RuffAnn HuysseunePaul Eckhard Witten

A refined system of vertebral column subdivision in Chinook salmon, Oncorhynchus tshawytscha (Actinopterygii : Salmonidae)

Adelbert De ClercqMatthew R. PerrottPeter S. DavieMark A. PreeceBen WybourneNicole RuffAnn HuysseunePaul Eckhard Witten

Vertebral deformities in 'wild' Chinook salmon Oncorhynchus tshawytscha in New Zealand

Adelbert De ClercqPeter S DavieSeumas P WalkerMatthew R PerrottJane E SymondsMark A PreeceJohn S Munday

2015

AquaScience New Zealand project update

Adelbert De ClercqMatthew R. PerrottPeter S. DavieMark A. PreeceBen WybourneNicole RuffSolenne MetayerAnn HuysseunePaul Eckhard Witten

Cryptic vertebral column deformities in fast growing larval Chinook salmon (O. tshawytscha)

Adelbert De ClercqMatthew R PerrottPeter S DavieAnn HuysseuneEckhard Witten

Extra teeth in the pharyngeal dentition of slow developing zebrafish

Iris WoltmannFedor ShkilAdelbert De ClercqAnn HuysseuneEckhard Witten

Implications of meristic variation in the vertebral column of zebrafish

Adelbert De ClercqAnn HuysseuneFedor ShkilMatthew R PerrottPeter S DavieIris WoltmannEckhard Witten

2014

A comparison of the larval and juvenile dentition in Polypterus senegalus

Adelbert De ClercqSam VandenplasAnn Huysseune

A1 Journal Article in JOURNAL OF APPLIED ICHTHYOLOGY

Tooth replacement without a dental lamina: the search for epithelial stem cells in Polypterus senegalus

Sam VandenplasAdelbert De ClercqAnn Huysseune

A1 Journal Article in JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

2013

Aspects of tooth replacement in a basal actinopterygian, Polypterus senegalus

Sam VandenplasAdelbert De ClercqAnn Huysseune

2012

Identification of potential epithelial stem cells responsible for continuous tooth replacement in the African bichir (Polypterus senegalus), a basal Osteichtyan

Adelbert De ClercqSam VandenplasAnn Huysseune